Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" A1BG ENSG00000121410 "Alpha-1-B glycoprotein" P04217 19 58345178-58353492 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1513 "liver: 1194.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 18.2;Oligodendrocytes: 8.1;Plasma cells: 8.2" "Cancer enriched" "Detected in single" 85 "liver cancer: 22.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB016673, HPA044252" Supported "Secreted to blood" "No annotated function" NA NA 200000000000 51000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 17: Choroid plexus - Cilium" "Cluster 18: Liver cancer - Metabolism" "Cluster 7: T-cells - T-cell receptor" "CAB016673: AB_1611892, HPA044252: AB_2678876" "unprognostic (9.95e-2)" "unprognostic (5.31e-2)" "unprognostic (3.67e-2)" "unprognostic (3.44e-2)" "unprognostic (1.18e-1)" "unprognostic (1.66e-2)" "prognostic favorable (3.97e-4)" "unprognostic (1.09e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-1)" "unprognostic (1.47e-2)" "unprognostic (1.37e-2)" "unprognostic (4.19e-5)" "unprognostic (2.37e-2)" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (6.72e-2)" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1212.9;lung: 1626.5" "Cell type enhanced" "Detected in many" "Adipocytes: 1247.2;Cardiomyocytes: 393.1;Endothelial cells: 861.7;Hepatocytes: 654.0;Microglial cells: 339.1;Smooth muscle cells: 471.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Brain cancer: 48.1;liver cancer: 106.6;skin cancer: 72.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" "Enzyme inhibitor" NA NA 1630000000000 170000000000 "Cluster 1: T-cells - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 47: Endothelial cells - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 51 "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" A2ML1 "CPAMD9, FLJ25179, p170" ENSG00000166535 "Alpha-2-macroglobulin like 1" A8K2U0 12 8822621-8887001 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 540.7;vagina: 198.6" "Group enriched" "Detected in some" 5 "Squamous epithelial cells: 157.1;Suprabasal keratinocytes: 477.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 39.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 13.2" "Testis - Sertoli cells" "Low region specificity" "Detected in many" "HPA038847, HPA038848" Enhanced "Secreted in other tissues" "Enzyme inhibitor" NA NA 10000000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA038847: AB_2676236, HPA038848: AB_10672654" "unprognostic (1.13e-2)" "unprognostic (7.64e-2)" "unprognostic (1.04e-2)" "unprognostic (9.46e-3)" "unprognostic (2.14e-1)" "unprognostic (5.54e-3)" "unprognostic (4.59e-2)" "unprognostic (7.58e-3)" "unprognostic (2.63e-1)" "unprognostic (1.57e-1)" "unprognostic (1.15e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-9)" "unprognostic (2.28e-1)" "unprognostic (3.07e-1)" "unprognostic (5.88e-2)" "unprognostic (2.42e-2)" A4GNT alpha4GnT ENSG00000118017 Alpha-1,4-N-acetylglucosaminyltransferase Q9UNA3 3 138123713-138132390 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "stomach 1: 23.0" "Group enriched" "Detected in some" 75 "Cholangiocytes: 3.8;Gastric mucus-secreting cells: 14.1" "Group enriched" "Detected in some" 6 "pancreatic cancer: 2.5;stomach cancer: 3.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008017 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 3: Choroid plexus - Cilium" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" "HPA008017: AB_1078073" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (2.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.48e-2)" "unprognostic (8.79e-2)" "unprognostic (9.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.81e-1)" "unprognostic (1.85e-1)" "unprognostic (4.03e-2)" "unprognostic (1.03e-1)" "unprognostic (7.79e-2)" "unprognostic (2.55e-2)" "unprognostic (6.48e-3)" AADACL2 MGC72001 ENSG00000197953 "Arylacetamide deacetylase like 2" Q6P093 3 151733916-151761339 "Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 34.5" "Cell type enriched" "Detected in some" 12 "Suprabasal keratinocytes: 32.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Colon - Fibroblasts, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA "Cluster 13: Skin - Cornification" "Cluster 59: Suprabasal keratinocytes - Cornification" "unprognostic (2.20e-2)" "unprognostic (3.10e-3)" "unprognostic (2.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (3.00e-1)" "unprognostic (2.91e-4)" AANAT SNAT ENSG00000129673 "Aralkylamine N-acetyltransferase" Q16613 17 76453351-76470117 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Melatonin biosynthesis" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 10.6;testis: 4.5" "Cell type enriched" "Detected in some" 12 "Bipolar cells: 227.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054321 Supported Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" 3 Cytosol "HPA054321: AB_2682449" "unprognostic (7.89e-2)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.83e-2)" "unprognostic (2.03e-2)" "unprognostic (1.05e-2)" "unprognostic (3.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.61e-1)" "unprognostic (9.30e-2)" "unprognostic (4.19e-1)" "unprognostic (2.81e-7)" "unprognostic (1.04e-1)" "unprognostic (6.00e-2)" "unprognostic (4.47e-2)" "unprognostic (1.34e-2)" ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 13.9;Excitatory neurons: 12.5;Gastric mucus-secreting cells: 4.7;Inhibitory neurons: 10.4;Oligodendrocyte precursor cells: 12.7;Oligodendrocytes: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" Transport NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol" "HPA046723: AB_10960288, HPA058011: AB_2683578" "unprognostic (8.04e-2)" "unprognostic (3.22e-2)" "unprognostic (4.53e-3)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (9.45e-7)" "unprognostic (2.26e-1)" "unprognostic (3.62e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-4)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.51e-1)" "unprognostic (9.55e-2)" "unprognostic (7.75e-2)" "unprognostic (2.30e-1)" ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10, depalmitoylase" Q9NUJ1 3 111979010-111993368 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria "Intracellular and membrane" Enzyme No No 71000 "Cluster 32: Basophils - Transcription" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA036991: AB_2675420, HPA036992: AB_10672345, HPA066081: AB_2685610" "unprognostic (1.65e-1)" "prognostic favorable (7.57e-4)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (1.14e-1)" "unprognostic (8.50e-2)" "unprognostic (1.69e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-2)" "prognostic favorable (4.72e-9)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (4.18e-3)" "unprognostic (2.76e-2)" ABHD15 ENSG00000168792 "Abhydrolase domain containing 15" Q6UXT9 17 29560547-29567037 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 25.4" "Cell type enriched" "Detected in many" 6 "dendritic cells: 175.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.2;MAIT T-cell: 6.6;NK-cell: 10.8;plasmacytoid DC: 23.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA014470 Approved Approved Nucleoplasm,Cytosol "Secreted to blood" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 11: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 28: Dendritic cells - Antigen presentation" 4 "Nucleoplasm, Cytosol" "HPA014470: AB_1852993" "unprognostic (1.79e-1)" "unprognostic (4.00e-2)" "unprognostic (1.38e-1)" "unprognostic (8.60e-3)" "unprognostic (1.91e-1)" "unprognostic (1.62e-1)" "unprognostic (4.61e-1)" "unprognostic (1.87e-1)" "unprognostic (1.85e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-3)" "unprognostic (3.00e-2)" "unprognostic (3.58e-2)" "unprognostic (1.70e-1)" "unprognostic (1.71e-1)" "unprognostic (3.46e-1)" "unprognostic (5.45e-2)" ABHD18 "C4orf29, FLJ21106" ENSG00000164074 "Abhydrolase domain containing 18" Q0P651 4 127965306-128039953 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 71.1;Inhibitory neurons: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050168, HPA051676" Approved Approved "Nuclear membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 35: Non-specific - Mitochondria" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 8: Neurons - Neuronal signaling" "Nuclear membrane" "HPA050168: AB_2681040, HPA051676: AB_2681571" "unprognostic (1.91e-1)" "unprognostic (8.66e-2)" "prognostic favorable (5.35e-4)" "unprognostic (1.74e-2)" "unprognostic (4.99e-2)" "unprognostic (2.52e-2)" "unprognostic (1.82e-1)" "unprognostic (1.51e-2)" "unprognostic (5.60e-2)" "unprognostic (3.34e-1)" "unprognostic (1.14e-2)" "unprognostic (1.76e-3)" "unprognostic (2.17e-3)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" "unprognostic (7.32e-2)" "prognostic favorable (9.13e-4)" ABI3BP "DKFZP586L2024, NESHBP, TARSH" ENSG00000154175 "ABI family member 3 binding protein" Q7Z7G0 3 100749156-100993515 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 211.2;Leydig cells: 97.9;Lymphatic endothelial cells: 155.1;Muller glia cells: 78.9" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 43.0;thyroid cancer: 49.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 15.9;cerebellum: 5.5;cerebral cortex: 13.9;olfactory bulb: 12.0" "Low region specificity" "Detected in all" HPA044127 Uncertain "Secreted in other tissues" "No annotated function" NA NA 550000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA044127: AB_2678823" "unprognostic (4.32e-2)" "unprognostic (3.32e-2)" "unprognostic (6.36e-2)" "unprognostic (3.41e-1)" "unprognostic (1.70e-1)" "unprognostic (7.20e-2)" "unprognostic (7.58e-2)" "unprognostic (6.25e-2)" "unprognostic (1.61e-1)" "unprognostic (2.36e-1)" "unprognostic (1.08e-1)" "unprognostic (9.46e-2)" "prognostic favorable (6.14e-4)" "unprognostic (2.27e-2)" "unprognostic (2.69e-2)" "unprognostic (6.59e-2)" "unprognostic (1.07e-3)" ABO "A3GALNT, A3GALT1" ENSG00000175164 "ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase" 9 133233278-133276024 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 12.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 89.9;Enteroendocrine cells: 72.7;Intestinal goblet cells: 83.7;Proximal enterocytes: 189.2;Undifferentiated cells: 66.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.1;naive B-cell: 2.1" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Gallbladder cancer: 91.2" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 45: Intestine - Digestion" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (2.78e-3)" "unprognostic (2.56e-3)" "unprognostic (1.38e-1)" "unprognostic (1.87e-3)" "unprognostic (1.39e-1)" "unprognostic (3.10e-2)" "unprognostic (1.84e-3)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" "unprognostic (8.51e-2)" "unprognostic (9.30e-3)" "unprognostic (7.23e-2)" "unprognostic (2.67e-2)" "unprognostic (4.57e-3)" "unprognostic (1.50e-1)" "unprognostic (2.34e-1)" "unprognostic (9.04e-2)" ACACB "ACACbeta, ACC-beta, ACC2, ACCB, ACCbeta, HACC275" ENSG00000076555 "Acetyl-CoA carboxylase beta" O00763 12 109116587-109268226 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Allosteric enzyme, Ligase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 176.9;skeletal muscle: 167.0" "Cell type enhanced" "Detected in many" "Adipocytes: 120.0;Astrocytes: 129.7;Hepatocytes: 166.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 17.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 17.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006554 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 17: Breast glandular cells - Lactation" 1 "HPA006554: AB_1844495" "unprognostic (2.24e-1)" "unprognostic (4.66e-1)" "unprognostic (3.97e-2)" "unprognostic (4.54e-6)" "unprognostic (2.82e-1)" "unprognostic (1.59e-2)" "unprognostic (8.62e-3)" "unprognostic (5.81e-2)" "unprognostic (2.86e-1)" "unprognostic (1.63e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.63e-2)" "prognostic favorable (1.15e-5)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.21e-3)" "unprognostic (2.58e-2)" ACAN "AGC1, CSPG1, CSPGCP, MSK16" ENSG00000157766 Aggrecan P16112 15 88803436-88875353 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "seminal vesicle: 3.0" "Cell type enriched" "Detected in some" 16 "Extravillous trophoblasts: 152.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 7.5;skin cancer: 8.0" "Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB016377, HPA038241, HPA038242" Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 17000000 "Cluster 64: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "CAB016377: AB_626650, HPA038241: AB_2675909, HPA038242: AB_2675910" "unprognostic (2.69e-3)" "unprognostic (4.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.43e-2)" "unprognostic (2.13e-2)" "unprognostic (1.40e-2)" "unprognostic (1.15e-1)" "unprognostic (7.12e-2)" "unprognostic (8.57e-2)" "unprognostic (2.34e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (7.79e-2)" "unprognostic (1.53e-1)" "unprognostic (7.71e-2)" "unprognostic (7.27e-2)" ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Calmodulin-binding, Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 257.7;testis: 99.0" "Group enriched" "Detected in many" 20 "Early spermatids: 373.5;Late spermatids: 1317.0;Proximal enterocytes: 1039.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.2" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Fibroblast_1, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" Enzyme NA NA 104000000 170000000 "Cluster 14: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" ACE2 ACEH ENSG00000130234 "Angiotensin converting enzyme 2" Q9BYF1 X 15494566-15607236 "Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Carboxypeptidase, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 64.1;intestine: 237.9;kidney: 85.2" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 201.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 13.9;renal cancer: 26.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA000288, CAB026174, CAB026213, CAB080024, CAB080025, CAB080027, CAB080028" Enhanced "Secreted to blood" Receptor NA NA 4530000 400000 "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" 13 "CAB026174: , CAB026213: , CAB080024: AB_10864415, CAB080025: AB_2809589, CAB080027: AB_2665870, CAB080028: AB_2665871, HPA000288: AB_1078160" "unprognostic (1.40e-1)" "unprognostic (7.26e-2)" "unprognostic (2.76e-2)" "unprognostic (5.71e-2)" "unprognostic (2.51e-1)" "unprognostic (5.26e-2)" "prognostic favorable (4.21e-4)" "unprognostic (2.34e-2)" "unprognostic (6.74e-3)" "unprognostic (2.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "prognostic favorable (2.12e-5)" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (2.11e-1)" "unprognostic (7.10e-2)" ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 104.5;skeletal muscle: 157.4;tongue: 46.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.1;Erythroid cells: 33.0;Exocrine glandular cells: 63.2;Horizontal cells: 59.2;Paneth cells: 39.8;Proximal enterocytes: 39.3;Skeletal myocytes: 80.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 990000 "Cluster 79: Non-specific - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 3 "Golgi apparatus" Vesicles "HPA027098: AB_2672111" "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" ACP3 "ACP-3, ACPP, PAP, TM-PAP" ENSG00000014257 "Acid phosphatase 3" P15309 3 132317369-132368302 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 76 "prostate: 3512.4" "Cell type enriched" "Detected in many" 443 "Prostatic glandular cells: 16688.0" "Cancer enriched" "Detected in many" 275 "prostate cancer: 1227.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 139.9" "Lineage enhanced" "Detected in many" "granulocytes: 139.9" "Cancer enriched" "Detected in many" 36 "prostate cancer: 250.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000071, HPA004335, HPA063916" Enhanced "Secreted to blood" Enzyme NA NA 460000 480000 "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Neuronal - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "CAB000071: , HPA004335: AB_1079684, HPA063916: AB_2685152" "unprognostic (6.67e-2)" "unprognostic (4.70e-2)" "unprognostic (1.76e-1)" "unprognostic (7.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.58e-2)" "unprognostic (2.46e-1)" "unprognostic (7.41e-2)" "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (2.14e-1)" "unprognostic (5.95e-2)" "unprognostic (9.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-1)" "unprognostic (3.91e-2)" "unprognostic (1.71e-1)" ACP5 "HPAP, TRAcP, TRAP" ENSG00000102575 "Acid phosphatase 5, tartrate resistant" P13686 19 11574653-11579993 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 159.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 391.8;Macrophages: 293.4;Proximal tubular cells: 109.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 27.0" "Immune cell enhanced" "Detected in many" "memory B-cell: 172.5" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 7 "skin cancer: 80.1" "Adipose subcutaneous - Macrophages, Kidney - Proximal tubular cells, Liver - Sinusoid Endothelial cells, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002584, HPA057655, HPA059463" Enhanced Uncertain Cytosol "Intracellular and membrane" Enzyme NA NA 4000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Macrophages - Innate immune response" Cytosol "CAB002584: AB_564039, HPA057655: AB_2683490, HPA059463: AB_2684028" "unprognostic (4.27e-2)" "unprognostic (2.05e-2)" "unprognostic (2.93e-1)" "unprognostic (8.60e-3)" "unprognostic (2.96e-1)" "unprognostic (1.95e-2)" "unprognostic (5.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.13e-2)" "unprognostic (3.80e-1)" "unprognostic (3.66e-3)" "unprognostic (9.09e-2)" "unprognostic (1.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" ACP6 "ACPL1, LPAP" ENSG00000162836 "Acid phosphatase 6, lysophosphatidic" Q9NPH0 1 147629652-147670524 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028560 Uncertain "Intracellular and membrane" Enzyme NA NA 64000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Astrocytes - Unknown function" "HPA028560: AB_10602427" "unprognostic (3.17e-2)" "unprognostic (3.01e-2)" "unprognostic (3.50e-1)" "unprognostic (1.87e-2)" "unprognostic (3.85e-1)" "unprognostic (8.50e-3)" "unprognostic (3.36e-3)" "unprognostic (1.00e-1)" "unprognostic (6.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (3.94e-1)" "unprognostic (8.07e-2)" "unprognostic (1.26e-1)" "prognostic favorable (6.44e-4)" ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.2;skin 1: 5.8" "Cell type enriched" "Detected in some" 5 "Oligodendrocytes: 10.0" "Group enriched" "Detected in some" 5 "cervical cancer: 0.8;head and neck cancer: 2.6;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Oligodendrocytes - Unknown function" "HPA042613: AB_10963214" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-3)" "unprognostic (1.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (4.94e-3)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" "unprognostic (1.51e-5)" "unprognostic (4.36e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-2)" "unprognostic (2.42e-1)" ACR ENSG00000100312 Acrosin P10323 22 50738196-50745339 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "testis: 84.3" "Group enriched" "Detected in some" 33 "Early spermatids: 278.9;Late spermatids: 93.1;Spermatocytes: 76.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "choroid plexus: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA048687 Enhanced "Secreted in male reproductive system" Enzyme NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA048687: AB_2680494" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "unprognostic (6.27e-3)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (3.30e-3)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (1.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" ACRBP "CT23, OY-TES-1, SP32" ENSG00000111644 "Acrosin binding protein" Q8NEB7 12 6638075-6647433 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "testis: 275.6" "Group enriched" "Detected in many" 68 "Early spermatids: 1140.3;Late spermatids: 787.6;Spermatocytes: 310.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 12.5;intermediate monocyte: 15.8;myeloid DC: 17.7;non-classical monocyte: 31.2" "Group enriched" "Detected in many" 9 "dendritic cells: 17.7;monocytes: 31.2" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039081, HPA039082" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 42: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 57: Platelets - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "HPA039081: AB_10670920, HPA039082: AB_10671036" "unprognostic (7.76e-3)" "unprognostic (2.27e-1)" "unprognostic (3.41e-3)" "unprognostic (2.31e-2)" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (2.42e-1)" "unprognostic (3.40e-3)" "unprognostic (2.85e-1)" "unprognostic (5.47e-3)" "unprognostic (1.17e-2)" "unprognostic (1.43e-1)" "unprognostic (9.41e-3)" "unprognostic (1.25e-1)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-4)" ACRV1 "D11S4365, SP-10, SPACA2" ENSG00000134940 "Acrosomal vesicle protein 1" P26436 11 125671522-125680874 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 113.4" "Group enriched" "Detected in some" 69 "Early spermatids: 1033.1;Late spermatids: 374.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038718, HPA038719" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" 3 "HPA038718: AB_2676171, HPA038719: AB_10670787" "unprognostic (3.58e-2)" "unprognostic (8.68e-3)" "unprognostic (1.46e-1)" "unprognostic (6.18e-2)" "unprognostic (4.58e-2)" "unprognostic (7.91e-3)" "unprognostic (6.73e-4)" "unprognostic (1.76e-1)" "unprognostic (2.12e-3)" "unprognostic (8.39e-2)" "unprognostic (7.09e-2)" "unprognostic (2.90e-3)" "unprognostic (1.80e-8)" "unprognostic (5.26e-3)" "unprognostic (2.52e-1)" "unprognostic (1.95e-1)" "unprognostic (3.75e-1)" ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157628864 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 25.3;Leydig cells: 34.1;Oligodendrocytes: 51.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 6.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 38.9" "HPA007982, HPA011933" Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" ACVRL1 "ACVRLK1, ALK1, HHT, HHT2, ORW2" ENSG00000139567 "Activin A receptor like type 1" P37023 12 51906908-51923361 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 93.3" "Cell type enhanced" "Detected in many" "Adipocytes: 98.8;Distal enterocytes: 137.5;Endothelial cells: 95.6;Extravillous trophoblasts: 44.0;Fibroblasts: 58.0;Lymphatic endothelial cells: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 19 "classical monocyte: 1.5;myeloid DC: 2.1" "Group enriched" "Detected in many" 19 "dendritic cells: 2.1;monocytes: 1.5" "Cancer enhanced" "Detected in some" "Neuroblastoma: 8.0" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007041 Approved "Intracellular and membrane" Receptor NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 57: Lung - Lung function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "HPA007041: AB_1078097" "unprognostic (2.50e-1)" "unprognostic (4.83e-1)" "unprognostic (3.79e-2)" "unprognostic (3.61e-2)" "unprognostic (4.98e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (5.10e-2)" "unprognostic (4.60e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-3)" "unprognostic (1.39e-1)" "unprognostic (7.98e-3)" "unprognostic (2.79e-1)" "unprognostic (1.10e-1)" ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17258235 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.0" "Cell type enhanced" "Detected in many" "dendritic cells: 117.0;Hofbauer cells: 91.6;Kupffer cells: 215.4;Langerhans cells: 133.1;Macrophages: 139.4;monocytes: 190.8;Plasma cells: 74.8;Schwann cells: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 15.1;lymphoma: 7.8;Myeloma: 23.5;Rhabdoid: 7.1;testis cancer: 17.4" "Lung - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" Enzyme NA NA 58000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" "HPA007888: AB_1078495" "unprognostic (1.03e-3)" "unprognostic (2.00e-3)" "unprognostic (6.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (4.48e-2)" "unprognostic (3.09e-3)" "unprognostic (3.80e-2)" "prognostic favorable (9.26e-4)" "prognostic favorable (8.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (4.86e-3)" "unprognostic (1.96e-2)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" ADAM10 "CD156C, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588809-58749791 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 351.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA 690000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 16: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 51: Oligodendrocytes - Unknown function" 17 "Vesicles, Plasma membrane" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavorable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388477 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 130.4" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 479.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 4.5" "Lineage enriched" "Detected in single" 45 "T-cells: 4.5" "Cancer enhanced" "Detected in many" "Brain cancer: 41.1;Kidney cancer: 31.8" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" "Cell adhesion" NA NA 14000000 "Cluster 1: T-cells - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" 5 "Plasma membrane" "HPA030866: AB_2673636, HPA030867: AB_10602428, HPA030868: AB_2673638" "unprognostic (3.35e-1)" "unprognostic (1.05e-3)" "unprognostic (3.52e-2)" "unprognostic (2.47e-2)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.91e-6)" "unprognostic (2.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.39e-14)" "unprognostic (3.11e-3)" "unprognostic (9.06e-3)" "unprognostic (4.70e-3)" "unprognostic (3.47e-3)" ADAM18 "ADAM27, tMDCIII" ENSG00000168619 "ADAM metallopeptidase domain 18" Q9Y3Q7 8 39584489-39730065 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 74 "testis: 8.9" "Group enriched" "Detected in some" 4 "Early spermatids: 81.0;Spermatocytes: 115.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 31: Spermatocytes - Spermatogenesis" "unprognostic (2.10e-4)" "unprognostic (1.18e-1)" ADAM23 MDC3 ENSG00000114948 "ADAM metallopeptidase domain 23" O75077 2 206443532-206621127 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.6;parathyroid gland: 80.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 81.1;Excitatory neurons: 396.2;Inhibitory neurons: 227.1;Late spermatids: 59.9;Oligodendrocyte precursor cells: 119.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "memory CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 16 "T-cells: 2.1" "Cancer enhanced" "Detected in many" "Myeloma: 47.8" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033276 Approved "Secreted in brain" "Cell adhesion" NA NA 890000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" "CAB033276: AB_2305247" "unprognostic (7.33e-2)" "unprognostic (7.80e-2)" "unprognostic (4.60e-1)" "unprognostic (5.77e-2)" "unprognostic (1.58e-1)" "unprognostic (3.59e-2)" "unprognostic (4.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" "unprognostic (6.84e-2)" "unprognostic (1.09e-2)" "unprognostic (2.64e-2)" "unprognostic (9.75e-6)" "unprognostic (3.32e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-3)" "unprognostic (1.03e-3)" ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 347.9;stomach 1: 107.1" "Cell type enhanced" "Detected in many" "B-cells: 223.9;Gastric mucus-secreting cells: 131.5;Ionocytes: 76.2;Microglial cells: 222.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 72.0;naive B-cell: 87.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" Enzyme NA NA "Cluster 32: Basophils - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 73: B-cells - B-cell function" 1 "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" ADAM7 "EAPI, GP-83" ENSG00000069206 "ADAM metallopeptidase domain 7" Q9H2U9 8 24440930-24526970 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 239 "epididymis: 3638.5" "Cell type enriched" "Detected in some" 11 "Early spermatids: 128.4" "Group enriched" "Detected in some" 16 "prostate cancer: 1.0;renal cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "prostate cancer: 2.5" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008879 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" "HPA008879: AB_10601789" "unprognostic (1.03e-3)" "unprognostic (3.96e-4)" ADAM8 "CD156, CD156A, MS2" ENSG00000151651 "ADAM metallopeptidase domain 8" P78325 10 133262420-133276868 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 67.8;lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 105.8;Langerhans cells: 163.3;NK-cells: 68.3;T-cells: 36.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 44.4" "Group enriched" "Detected in many" 5 "basophil: 107.8;eosinophil: 259.4;neutrophil: 139.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 259.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 53.8" "Adipose visceral - Neutrophils, Breast - T-cells, Heart muscle - Neutrophils, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA064637 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 14: Langerhans cells - Innate immune response" 4 "HPA064637: AB_2685306" "unprognostic (8.24e-2)" "unprognostic (6.07e-3)" "unprognostic (1.27e-3)" "unprognostic (5.18e-2)" "unprognostic (8.26e-2)" "unprognostic (6.47e-2)" "unprognostic (5.59e-2)" "unprognostic (2.22e-1)" "unprognostic (2.57e-1)" "unprognostic (1.94e-3)" "unprognostic (3.37e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (3.99e-10)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.28e-1)" "unprognostic (9.32e-2)" ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 172.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" Enzyme NA NA 740000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 4 Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" ADAMDEC1 M12.219 ENSG00000134028 "ADAM like decysin 1" O15204 8 24384285-24406013 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 413.0" "Group enriched" "Detected in some" 4 "Hofbauer cells: 13.0;Kupffer cells: 11.2;Macrophages: 28.4" "Cancer enhanced" "Detected in all" "testis cancer: 16.7" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Adipose visceral - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted in other tissues" Enzyme NA NA 28000000 "Cluster 45: Intestine - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" "unprognostic (1.17e-2)" "unprognostic (1.80e-2)" "unprognostic (4.15e-3)" "unprognostic (3.60e-1)" "unprognostic (6.21e-2)" "unprognostic (3.84e-3)" "unprognostic (2.12e-1)" "unprognostic (2.90e-1)" "unprognostic (1.61e-1)" "unprognostic (5.99e-3)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (1.74e-2)" "unprognostic (2.06e-1)" "unprognostic (1.35e-2)" "unprognostic (3.66e-2)" "unprognostic (8.23e-2)" ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 300.2" "Cell type enhanced" "Detected in many" "Adipocytes: 338.6;Endothelial cells: 410.5;Extravillous trophoblasts: 257.2;Fibroblasts: 251.9;Smooth muscle cells: 574.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 41.6" "CAB016394, HPA031498" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" Enzyme NA NA 4100000 "Cluster 15: NK-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 3 "Plasma membrane" "CAB016394: AB_626637, HPA031498: AB_2673907" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (9.70e-3)" "unprognostic (8.27e-3)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (1.57e-1)" ADAMTS10 ADAM-TS10 ENSG00000142303 "ADAM metallopeptidase with thrombospondin type 1 motif 10" Q9H324 19 8580240-8610735 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 17.3;Excitatory neurons: 20.7;Inhibitory neurons: 19.1;Microglial cells: 29.5;Smooth muscle cells: 14.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 7.5" "Region enriched" "Detected in many" 5 "cerebellum: 8.8" "Low region specificity" "Detected in all" HPA040223 Uncertain "Secreted to extracellular matrix" Enzyme NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA040223: AB_10795376" "unprognostic (2.60e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (1.14e-1)" "unprognostic (8.16e-2)" "unprognostic (1.91e-4)" "unprognostic (4.98e-3)" "unprognostic (4.06e-2)" "unprognostic (2.24e-2)" "unprognostic (6.52e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (6.86e-3)" "unprognostic (1.71e-1)" "unprognostic (2.33e-1)" "unprognostic (4.12e-2)" ADAMTS12 ENSG00000151388 "ADAM metallopeptidase with thrombospondin type 1 motif 12" P58397 5 33523535-33892019 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 24.3;Fibroblasts: 18.2;Leydig cells: 23.6;Microglial cells: 69.8;Peritubular cells: 17.5;Sertoli cells: 24.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 70.1;testis cancer: 34.0" "Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035973, HPA075079" Uncertain Approved Nucleoli,Mitochondria "Secreted to extracellular matrix" Enzyme NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 50: Connective tissue cells - ECM organization" 3 Nucleoli Mitochondria "HPA035973: AB_10669663, HPA075079: AB_2732278" "unprognostic (6.18e-3)" "unprognostic (3.12e-4)" "unprognostic (1.05e-1)" "unprognostic (8.37e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-1)" "unprognostic (2.60e-2)" "unprognostic (3.49e-3)" "unprognostic (3.78e-3)" "unprognostic (3.39e-2)" "unprognostic (5.63e-3)" "unprognostic (1.45e-1)" "unprognostic (4.27e-7)" "unprognostic (4.45e-3)" "unprognostic (1.47e-1)" "unprognostic (5.85e-2)" "prognostic unfavorable (6.78e-4)" ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 62.2" "Cell type enhanced" "Detected in many" "Astrocytes: 15.2;Early spermatids: 12.2;Excitatory neurons: 12.0;Inhibitory neurons: 11.9;Late spermatids: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 1300000000 120000000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 13: Spermatids - Transcription" 1 Vesicles "HPA042014: AB_2677798, HPA042844: AB_2678200, HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" ADAMTS14 ENSG00000138316 "ADAM metallopeptidase with thrombospondin type 1 motif 14" Q8WXS8 10 70672506-70762441 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 6.5;placenta: 7.3" "Group enriched" "Detected in some" 10 "Oligodendrocytes: 41.7;Paneth cells: 17.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 51: Oligodendrocytes - Unknown function" "unprognostic (1.30e-1)" "unprognostic (1.04e-2)" "unprognostic (5.98e-3)" "unprognostic (3.54e-3)" "unprognostic (2.17e-3)" "unprognostic (2.40e-1)" "unprognostic (5.33e-3)" "unprognostic (2.35e-1)" "unprognostic (1.06e-1)" "unprognostic (3.28e-2)" "unprognostic (3.98e-2)" "unprognostic (6.81e-2)" "unprognostic (3.84e-13)" "unprognostic (3.90e-2)" "unprognostic (1.14e-1)" "unprognostic (1.81e-1)" "unprognostic (2.16e-2)" ADAMTS15 ENSG00000166106 "ADAM metallopeptidase with thrombospondin type 1 motif 15" Q8TE58 11 130448645-130476645 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.5" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Endometrial stromal cells: 14.4;Fibroblasts: 6.2;Glandular and luminal cells: 6.3;Lymphatic endothelial cells: 7.7;Mesothelial cells: 16.7" "Cancer enhanced" "Detected in many" "breast cancer: 13.2" "Region enhanced" "Detected in many" "medulla oblongata: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042867 Uncertain Approved Cytosol "Secreted to extracellular matrix" Enzyme NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" Cytosol "HPA042867: AB_10794535" "unprognostic (7.64e-2)" "unprognostic (1.49e-3)" "unprognostic (7.15e-2)" "unprognostic (1.34e-3)" "unprognostic (1.07e-3)" "unprognostic (7.07e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.72e-4)" "unprognostic (6.18e-2)" "unprognostic (4.37e-2)" "unprognostic (2.56e-1)" "unprognostic (7.40e-2)" "unprognostic (1.29e-2)" "unprognostic (5.95e-3)" "unprognostic (6.68e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.63e-5)" ADAMTS16 ADAMTS16s ENSG00000145536 "ADAM metallopeptidase with thrombospondin type 1 motif 16" Q8TE57 5 5140330-5320304 "Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.0;ovary: 23.4" "Group enriched" "Detected in some" 4 "Excitatory neurons: 43.2;Ovarian stromal cells: 15.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Fibroblasts, Lung - Fibroblast_2, Skin - Fibroblast_1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA061013 Approved Vesicles "Secreted to extracellular matrix" Enzyme NA No "Cluster 64: Neuronal - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA061013: " "unprognostic (8.48e-2)" "unprognostic (1.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.98e-4)" "unprognostic (1.91e-2)" "unprognostic (5.04e-2)" "unprognostic (7.64e-2)" "unprognostic (7.80e-3)" "unprognostic (2.12e-2)" "unprognostic (5.44e-2)" "unprognostic (1.51e-2)" "unprognostic (2.18e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.20e-4)" "unprognostic (1.46e-1)" "unprognostic (4.59e-3)" "unprognostic (2.86e-3)" ADAMTS17 "FLJ16363, FLJ32769" ENSG00000140470 "ADAM metallopeptidase with thrombospondin type 1 motif 17" Q8TE56 15 99971437-100342005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Deafness, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Cell type enhanced" "Detected in many" "Astrocytes: 110.8;Early spermatids: 75.3;Inhibitory neurons: 266.3;Late spermatids: 113.2;Oligodendrocyte precursor cells: 316.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.0" "Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062487 Approved Nucleoplasm "Secreted to extracellular matrix" Enzyme NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 8: Neurons - Neuronal signaling" Nucleoplasm "HPA062487: AB_2684780" "unprognostic (7.73e-2)" "unprognostic (2.38e-2)" "unprognostic (1.79e-2)" "unprognostic (9.03e-3)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (5.78e-2)" "unprognostic (1.18e-3)" "unprognostic (5.03e-3)" "unprognostic (4.70e-2)" "unprognostic (2.93e-1)" "unprognostic (1.27e-1)" "unprognostic (3.35e-2)" "unprognostic (8.48e-2)" "unprognostic (1.21e-1)" "unprognostic (7.43e-3)" "unprognostic (6.43e-2)" ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.3;placenta: 19.9" "Cell type enhanced" "Detected in some" "Adipocytes: 35.8;Muller glia cells: 10.3;Oligodendrocytes: 15.6;Oocytes: 15.4;Rod photoreceptor cells: 8.3;Serous glandular cells: 8.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "liver cancer: 2.6;testis cancer: 9.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Enzyme Yes NA "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" "Midbody, Mitotic spindle" "HPA044326: AB_10961006" "unprognostic (1.10e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (8.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.20e-2)" "unprognostic (8.17e-4)" "unprognostic (1.77e-5)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.47e-4)" ADAMTS19 ENSG00000145808 "ADAM metallopeptidase with thrombospondin type 1 motif 19" 5 129460281-129738683 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "cervix: 9.8;endometrium 1: 9.5;placenta: 3.6;smooth muscle: 5.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 79.5;Inhibitory neurons: 75.8;Oligodendrocytes: 29.5" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.7;testis cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 7.7" "Kidney - Podocytes" "Region enriched" "Detected in single" 5 "olfactory bulb: 2.6" "Low region specificity" "Detected in all" "HPA056171, HPA058438" Uncertain Approved Vesicles,Midbody "Secreted to extracellular matrix" Yes NA "Cluster 62: Connective tissue - ECM organization" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" "Vesicles, Midbody" "HPA056171: AB_2683054, HPA058438: AB_2683718" "unprognostic (1.14e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-3)" "unprognostic (1.09e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-2)" "unprognostic (4.17e-2)" "unprognostic (5.99e-3)" "unprognostic (5.17e-1)" "unprognostic (1.14e-1)" "unprognostic (5.88e-2)" "unprognostic (3.06e-2)" ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 29.6;Fibroblasts: 35.1;Kupffer cells: 74.2;Macrophages: 19.6;Mesothelial cells: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" Enzyme NA NA 2000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" ADAMTS20 GON-1 ENSG00000173157 "ADAM metallopeptidase with thrombospondin type 1 motif 20" P59510 12 43353866-43552203 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bipolar cells: 4.6;Inhibitory neurons: 15.4;Oligodendrocyte precursor cells: 10.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "medulla oblongata: 3.6;pons: 6.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 9.4" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027608, HPA027609" Uncertain "Secreted to extracellular matrix" Enzyme NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 65: Neurons - Synaptic function" "HPA027608: AB_10600098, HPA027609: AB_10599024" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (1.91e-2)" "unprognostic (2.04e-1)" "unprognostic (9.61e-2)" "unprognostic (3.29e-1)" "unprognostic (6.67e-2)" "unprognostic (2.26e-1)" "unprognostic (1.05e-4)" "unprognostic (7.42e-2)" "unprognostic (2.02e-1)" "unprognostic (9.81e-3)" "unprognostic (2.57e-1)" ADAMTS3 "ADAMTS-4, KIAA0366" ENSG00000156140 "ADAM metallopeptidase with thrombospondin type 1 motif 3" O15072 4 72280969-72569221 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.1" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 32.3;Excitatory neurons: 48.5;Leydig cells: 23.6;Mesothelial cells: 14.7;Rod photoreceptor cells: 28.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 20.4" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021368, HPA021369" Uncertain Approved "Intermediate filaments" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 40: Non-specific - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 1 "Intermediate filaments" "HPA021368: AB_2670681, HPA021369: AB_2670682" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-3)" "unprognostic (6.11e-2)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (1.60e-3)" "unprognostic (5.92e-4)" "unprognostic (3.11e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (8.63e-3)" "unprognostic (1.65e-3)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" "unprognostic (1.50e-4)" ADAMTS4 "ADAMTS-2, ADMP-1, KIAA0688" ENSG00000158859 "ADAM metallopeptidase with thrombospondin type 1 motif 4" O75173 1 161184302-161199054 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 113.0;ovary: 92.8" "Cell type enhanced" "Detected in many" "Adipocytes: 76.5;Endothelial cells: 119.2;Fibroblasts: 76.3;Lymphatic endothelial cells: 41.4;Oligodendrocytes: 52.1;Smooth muscle cells: 203.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.4" "Cancer enhanced" "Detected in some" "Bone cancer: 8.1;skin cancer: 5.6" "Breast - Endothelial cells, Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025876, HPA051296, HPA068374" Uncertain Supported "Nuclear speckles" "Secreted to extracellular matrix" Enzyme NA NA 11000 "Cluster 30: Non-specific - DNA binding" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "Nuclear speckles" "CAB025876: , HPA051296: AB_2681426, HPA068374: AB_2685978" "unprognostic (2.70e-2)" "unprognostic (8.10e-3)" "unprognostic (3.00e-3)" "unprognostic (2.75e-1)" "unprognostic (9.95e-3)" "unprognostic (1.19e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.20e-2)" "unprognostic (9.59e-3)" "unprognostic (2.48e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.27e-7)" "unprognostic (1.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-3)" "unprognostic (3.13e-2)" ADAMTS5 "ADAMTS11, ADMP-2" ENSG00000154736 "ADAM metallopeptidase with thrombospondin type 1 motif 5" Q9UNA0 21 26917922-26967088 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 24.6;placenta: 25.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 48.3;Endometrial stromal cells: 86.2;Fibroblasts: 82.8;Leydig cells: 61.8;Ovarian stromal cells: 57.3;Smooth muscle cells: 51.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 6.8;thyroid cancer: 4.9" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA005661, CAB025996, HPA030906, HPA030908" Approved Supported Nucleoplasm "Secreted to extracellular matrix" Enzyme NA NA 28000 "Cluster 62: Connective tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm "CAB025996: , HPA005661: AB_1078101, HPA030906: AB_2673654, HPA030908: AB_2673655" "unprognostic (1.97e-1)" "unprognostic (2.88e-3)" "unprognostic (2.69e-2)" "unprognostic (4.01e-2)" "unprognostic (4.67e-1)" "unprognostic (2.10e-2)" "unprognostic (4.38e-8)" "unprognostic (1.11e-3)" "unprognostic (7.66e-2)" "unprognostic (6.17e-2)" "unprognostic (8.13e-2)" "unprognostic (7.76e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (6.69e-3)" "unprognostic (3.01e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.15e-1)" ADAMTS6 ADAM-TS6 ENSG00000049192 "ADAM metallopeptidase with thrombospondin type 1 motif 6" Q9UKP5 5 65148738-65481920 "Cancer-related genes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.9;Inhibitory neurons: 60.6;Lymphatic endothelial cells: 73.5;Oligodendrocyte precursor cells: 131.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043441 Enhanced "Secreted to extracellular matrix" Enzyme NA Yes "Cluster 62: Connective tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" "HPA043441: AB_2678484" "unprognostic (1.53e-1)" "unprognostic (1.40e-1)" "unprognostic (2.70e-3)" "unprognostic (4.33e-2)" "unprognostic (1.03e-2)" "unprognostic (2.39e-2)" "unprognostic (8.24e-2)" "unprognostic (1.65e-2)" "unprognostic (4.77e-2)" "unprognostic (8.04e-2)" "unprognostic (1.56e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-6)" "unprognostic (3.23e-5)" "unprognostic (2.09e-1)" "unprognostic (3.02e-4)" "unprognostic (4.18e-3)" ADAMTS7 "ADAM-TS7, DKFZp434H204" ENSG00000136378 "ADAM metallopeptidase with thrombospondin type 1 motif 7" Q9UKP4 15 78759206-78811464 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 29.6" "Cell type enhanced" "Detected in some" "Adipocytes: 6.1;Endometrial stromal cells: 6.5;granulocytes: 10.4;Mesothelial cells: 7.3;Oligodendrocyte precursor cells: 9.0;Schwann cells: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.4" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA045284, HPA048453" Uncertain Supported Vesicles "Secreted to extracellular matrix" Enzyme NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 49: HMC-1 - Innate immune response" "Cluster 50: Connective tissue cells - ECM organization" Vesicles "HPA045284: AB_2679285, HPA048453: AB_2680399" "unprognostic (5.94e-3)" "unprognostic (9.94e-3)" "unprognostic (2.76e-2)" "unprognostic (7.09e-2)" "unprognostic (3.38e-1)" "unprognostic (1.93e-1)" "unprognostic (5.88e-4)" "unprognostic (3.34e-3)" "unprognostic (2.89e-2)" "unprognostic (3.31e-2)" "unprognostic (1.83e-2)" "unprognostic (3.79e-1)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (8.86e-2)" ADAMTS8 "ADAM-TS8, FLJ41712, METH2" ENSG00000134917 "ADAM metallopeptidase with thrombospondin type 1 motif 8" Q9UP79 11 130404923-130428609 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 26.7" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 32.0;Fibroblasts: 18.0;Glandular and luminal cells: 27.0;Schwann cells: 9.6;Smooth muscle cells: 11.9" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Adrenocortical cancer: 6.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066349 Approved "Secreted to extracellular matrix" Enzyme NA NA 3600000 "Cluster 57: Lung - Lung function" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA066349: AB_2685662" "unprognostic (4.76e-6)" "unprognostic (3.92e-2)" "unprognostic (6.13e-2)" "prognostic favorable (1.38e-4)" "unprognostic (2.41e-1)" "unprognostic (7.81e-2)" "unprognostic (3.09e-2)" "unprognostic (9.83e-2)" "unprognostic (1.09e-4)" "unprognostic (3.05e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (4.66e-3)" "unprognostic (4.03e-3)" "unprognostic (5.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-1)" ADAMTS9 KIAA1312 ENSG00000163638 "ADAM metallopeptidase with thrombospondin type 1 motif 9" Q9P2N4 3 64515654-64688000 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 39.8" "Cell type enhanced" "Detected in many" "Adipocytes: 159.7;Astrocytes: 79.9;Endometrial stromal cells: 165.1;Endothelial cells: 174.4;Mesothelial cells: 119.2;Smooth muscle cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 45.5;testis cancer: 37.3" "Breast - Endothelial cells, Heart muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028567, HPA028577, HPA028601" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" Transport No NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Vesicles "Endoplasmic reticulum" "HPA028567: AB_10599275, HPA028577: AB_10600330, HPA028601: AB_2672694" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (4.83e-2)" "unprognostic (3.08e-1)" "unprognostic (1.37e-2)" "unprognostic (7.80e-3)" "unprognostic (5.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (7.67e-2)" "unprognostic (3.16e-3)" "unprognostic (1.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-3)" "unprognostic (5.00e-3)" ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 12.9;smooth muscle: 10.8" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 237.1" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 15.5;Sarcoma: 18.9" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" Enzyme NA NA 28000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 70.8;liver: 35.0" "Cell type enhanced" "Detected in many" "Distal tubular cells: 9.2;Fibroblasts: 9.2;Microglial cells: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.5" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA 170000000 "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 82.1;Excitatory neurons: 30.1;Inhibitory neurons: 87.4;Leydig cells: 47.3;Oligodendrocytes: 70.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 7.5" "Kidney - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA 270000 "Cluster 62: Connective tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" 13 Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" ADAMTSL4 "DKFZP434K1772, TSRC1" ENSG00000143382 "ADAMTS like 4" Q6UY14 1 150549369-150560937 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 143.9;Endometrial stromal cells: 36.6;Extravillous trophoblasts: 44.7;Skeletal myocytes: 50.7;Syncytiotrophoblasts: 93.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Bladder cancer: 39.1" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006279 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Other NA NA 110000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 7 "Plasma membrane, Cytosol" "HPA006279: AB_1078102" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (8.09e-4)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.68e-2)" "unprognostic (1.28e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-2)" "unprognostic (7.40e-3)" ADAMTSL5 THSD6 ENSG00000185761 "ADAMTS like 5" 19 1505022-1513604 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 8.9;Leydig cells: 19.9;Peritubular cells: 17.9;Proximal enterocytes: 11.3;Sertoli cells: 10.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Skeletal muscle - Skeletal myocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044050 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" "Golgi apparatus" "HPA044050: AB_10962625" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (5.85e-2)" "unprognostic (2.45e-1)" "unprognostic (1.10e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (1.77e-2)" "unprognostic (1.89e-1)" "unprognostic (2.79e-2)" "unprognostic (2.89e-3)" "unprognostic (1.52e-1)" "unprognostic (5.03e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-3)" ADCK1 FLJ39600 ENSG00000063761 "AarF domain containing kinase 1" Q86TW2 14 77800109-77935014 "Enzymes, Predicted secreted proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 27.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051012, HPA055014" Uncertain Uncertain Nucleoplasm "Secreted - unknown location" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Oligodendrocytes - Unknown function" Nucleoplasm "HPA051012: AB_2681310, HPA055014: AB_2682672" "unprognostic (6.36e-2)" "unprognostic (7.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.24e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.70e-4)" "prognostic favorable (4.11e-5)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (4.57e-3)" "unprognostic (1.38e-1)" "prognostic favorable (5.82e-6)" "unprognostic (6.30e-3)" "unprognostic (2.06e-1)" "unprognostic (9.57e-2)" "unprognostic (4.06e-1)" ADCYAP1 PACAP ENSG00000141433 "Adenylate cyclase activating polypeptide 1" P18509 18 904871-912172 "Predicted secreted proteins" Neurogenesis Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.0;lymphoid tissue: 10.6" "Group enriched" "Detected in some" 15 "granulocytes: 324.1;Pancreatic endocrine cells: 91.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 17.8;Rhabdoid: 20.7;thyroid cancer: 10.7" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065887 Supported Supported "Secreted in other tissues" Hormone NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 43: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 30: Granulocytes - Unknown function" 2 "HPA065887: " "unprognostic (2.68e-1)" "unprognostic (1.83e-2)" "unprognostic (7.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.87e-4)" "unprognostic (9.58e-3)" "unprognostic (1.00e-1)" "unprognostic (2.34e-1)" "unprognostic (6.86e-2)" "unprognostic (4.16e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.91e-6)" "unprognostic (2.24e-3)" "unprognostic (9.22e-2)" "unprognostic (1.74e-1)" "unprognostic (5.74e-4)" ADGRA3 "FLJ38547, GPR125, PGR21" ENSG00000152990 "Adhesion G protein-coupled receptor A3" Q8IWK6 4 22345071-22516066 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.5" "Cell type enhanced" "Detected in many" "Astrocytes: 210.2;Hepatocytes: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008904 Uncertain "Intracellular and membrane" Receptor NA NA 280000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 39: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 47: Astrocytes - Unknown function" "HPA008904: AB_1849258" "unprognostic (3.70e-1)" "unprognostic (9.01e-2)" "unprognostic (5.32e-3)" "unprognostic (8.27e-3)" "unprognostic (4.58e-2)" "unprognostic (1.55e-1)" "unprognostic (8.15e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (3.91e-2)" "unprognostic (8.77e-2)" "unprognostic (1.88e-1)" "unprognostic (1.78e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-3)" ADGRB1 BAI1 ENSG00000181790 "Adhesion G protein-coupled receptor B1" O14514 8 142449430-142545009 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity, Myogenesis, Neurogenesis, Phagocytosis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 46.9" "Cell type enhanced" "Detected in some" "Astrocytes: 55.7;Bipolar cells: 24.0;Excitatory neurons: 45.9;Horizontal cells: 46.6;Inhibitory neurons: 36.4;Oligodendrocyte precursor cells: 66.5" "Cancer enriched" "Detected in many" 5 "glioma: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" Receptor NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 70: DU4475 - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "unprognostic (9.57e-4)" "unprognostic (1.28e-1)" "unprognostic (3.87e-3)" "unprognostic (8.50e-3)" "unprognostic (9.98e-2)" "unprognostic (5.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.14e-2)" "unprognostic (2.76e-1)" "unprognostic (2.55e-1)" "unprognostic (6.48e-2)" "unprognostic (3.43e-1)" "unprognostic (7.30e-11)" "unprognostic (6.27e-2)" "unprognostic (7.42e-2)" "unprognostic (4.52e-3)" "unprognostic (3.29e-2)" ADGRE3 EMR3 ENSG00000131355 "Adhesion G protein-coupled receptor E3" Q9BY15 19 14619117-14690027 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.1;lymphoid tissue: 5.9" "Cell type enhanced" "Detected in some" "Macrophages: 7.7;Microglial cells: 3.6;monocytes: 21.0;Mucus glandular cells: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Group enriched" "Detected in many" 7 "basophil: 282.8;eosinophil: 510.3;neutrophil: 491.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 510.3" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.0" "Adipose visceral - Neutrophils, Stomach - Neutrophils" "Not detected" "Not detected" HPA015638 Uncertain "Secreted to blood" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "HPA015638: AB_1848039" "unprognostic (2.11e-4)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (5.69e-2)" "unprognostic (5.63e-2)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (8.07e-2)" "unprognostic (9.61e-2)" "unprognostic (9.11e-4)" "unprognostic (4.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.13e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" ADGRE5 "CD97, TM7LN1" ENSG00000123146 "Adhesion G protein-coupled receptor E5" P48960 19 14380501-14408725 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 209.5" "Cell type enhanced" "Detected in many" "dendritic cells: 152.0;monocytes: 445.8;NK-cells: 300.7;T-cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013707 Enhanced Approved Cytosol "Secreted to blood" Receptor NA Yes 10000000 2400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Cytosol "HPA013707: AB_1846345" "unprognostic (3.16e-1)" "unprognostic (1.80e-1)" "unprognostic (5.10e-2)" "unprognostic (2.30e-1)" "unprognostic (2.85e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (7.51e-2)" "unprognostic (6.06e-3)" "unprognostic (3.14e-2)" "unprognostic (1.08e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (2.08e-2)" "unprognostic (4.14e-2)" "unprognostic (2.44e-2)" "unprognostic (6.41e-2)" ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.0;kidney: 19.7;urinary bladder: 41.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 62.2;Ciliated cells: 66.8;Club cells: 124.5;Collecting duct cells: 101.1;Glandular and luminal cells: 55.9;Ionocytes: 157.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 62.2" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" Receptor NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 209.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 220.3;Melanocytes: 140.9;NK-cells: 180.6;Syncytiotrophoblasts: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.5" "Lineage enriched" "Detected in many" 5 "T-cells: 160.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Prostate basal glandular cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" Receptor NA NA 32000 "Cluster 24: Non-specific - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 19: NK-cells - Adaptive immune response" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" ADIPOQ "ACDC, ACRP30, adiponectin, apM1, GBP28" ENSG00000181092 "Adiponectin, C1Q and collagen domain containing" Q15848 3 186842704-186858463 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hormone "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 28 "adipose tissue: 866.9;breast: 241.0" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.5;Cone photoreceptor cells: 1.7;Smooth muscle cells: 1.5" "Group enriched" "Detected in some" 8 "breast cancer: 6.5;pancreatic cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB046467, HPA051767" Uncertain "Secreted to blood" Hormone NA NA 8360000000 910000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 46 "CAB046467: AB_1078104, HPA051767: AB_2681598" "unprognostic (1.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.20e-2)" "unprognostic (6.99e-3)" "unprognostic (1.87e-1)" ADM AM ENSG00000148926 Adrenomedullin P35318 11 10305073-10307397 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 329.3" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 1411.0;Syncytiotrophoblasts: 1281.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "neutrophil: 243.4" "Lineage enriched" "Detected in many" 18 "granulocytes: 243.4" "Low cancer specificity" "Detected in all" "Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016075, HPA068955" Approved "Secreted to blood" Hormone NA NA 31000 340000 "Cluster 4: Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" "CAB016075: AB_628693, HPA068955: " "unprognostic (1.67e-1)" "unprognostic (2.89e-2)" "unprognostic (1.78e-1)" "unprognostic (5.22e-2)" "unprognostic (1.55e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.78e-3)" "unprognostic (1.06e-1)" "unprognostic (2.83e-1)" "unprognostic (8.13e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (6.33e-4)" "unprognostic (9.70e-3)" "unprognostic (2.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.62e-2)" ADM2 "AM2, FLJ21135" ENSG00000128165 "Adrenomedullin 2" Q7Z4H4 22 50481543-50486440 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.1;pancreas: 15.0;thyroid gland: 11.2" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 12.4;Intestinal goblet cells: 7.4;Plasma cells: 9.1;Proximal enterocytes: 5.8;Proximal tubular cells: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Myeloma: 22.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Hormone NA NA 61300 "Cluster 68: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 38: Proximal tubular cells - Transmembrane transport" "unprognostic (1.30e-2)" "unprognostic (4.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-1)" "unprognostic (3.15e-1)" "unprognostic (4.62e-3)" "unprognostic (7.26e-3)" "unprognostic (1.50e-1)" "unprognostic (3.44e-1)" "unprognostic (7.20e-2)" "unprognostic (9.41e-2)" "unprognostic (7.30e-3)" "unprognostic (1.17e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.06e-2)" ADM5 "AM5, C19orf76" ENSG00000224420 "Adrenomedullin 5 (putative)" C9JUS6 19 49689594-49690575 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 37.1;Endothelial cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells" "Secreted to blood" "No annotated function" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "unprognostic (2.34e-2)" "unprognostic (2.56e-1)" "unprognostic (3.08e-3)" "unprognostic (5.62e-2)" "unprognostic (2.18e-2)" "unprognostic (2.64e-2)" "unprognostic (1.28e-1)" "unprognostic (2.39e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (1.47e-2)" "unprognostic (8.94e-2)" "unprognostic (4.21e-11)" "unprognostic (2.39e-2)" "unprognostic (9.25e-2)" "unprognostic (9.92e-3)" "prognostic favorable (6.74e-4)" ADPGK "ADP-GK, DKFZp434B195" ENSG00000159322 "ADP dependent glucokinase" Q9BRR6 15 72751294-72785846 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045194, HPA058525" Approved Approved Centrosome "Intracellular and membrane" Enzyme NA NA 66000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 58: Macrophages - Innate immune response" Centrosome "HPA045194: AB_10964638, HPA058525: AB_2683742" "unprognostic (5.96e-3)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.82e-1)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.45e-1)" "unprognostic (8.50e-2)" "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.22e-4)" "prognostic unfavorable (4.52e-7)" "unprognostic (1.92e-1)" "unprognostic (6.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.07e-2)" ADPRS "ADPRHL2, ARH3, FLJ20446" ENSG00000116863 "ADP-ribosylserine hydrolase" Q9NX46 1 36088892-36093932 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" Hydrolase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026641, HPA027104, HPA027141" Approved Enhanced Nucleoplasm "Intracellular and membrane" Enzyme NA NA 54000 "Cluster 29: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 1 Nucleoplasm "HPA026641: , HPA027104: AB_10601330, HPA027141: AB_1844619" "unprognostic (3.22e-3)" "unprognostic (5.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.61e-2)" "unprognostic (5.98e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.10e-7)" "unprognostic (3.71e-2)" "unprognostic (2.63e-1)" "unprognostic (5.34e-2)" "unprognostic (3.17e-2)" "unprognostic (7.80e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.37e-2)" "unprognostic (9.31e-2)" "unprognostic (3.65e-2)" "unprognostic (4.74e-2)" AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 277.4;Leydig cells: 148.2;Melanocytes: 115.1;Mesothelial cells: 112.7;Ovarian stromal cells: 158.2;Peritubular cells: 480.3;Smooth muscle cells: 212.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cancer enhanced" "Detected in many" "skin cancer: 76.4" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 77.4" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" Transcription NA NA 2700000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Smooth muscle cells - Muscle contraction" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" AFG1L "AFG1, LACE1" ENSG00000135537 "AFG1 like ATPase" Q8WV93 6 108294991-108526796 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 745.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030154, HPA030155, HPA030659" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 18: Non-specific - Translation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 18: Early spermatids - Unknown function" 2 "HPA030154: AB_10600769, HPA030155: AB_10601232, HPA030659: AB_10602415" "unprognostic (9.76e-5)" "unprognostic (1.72e-1)" "unprognostic (1.68e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-1)" "unprognostic (7.04e-2)" "unprognostic (2.57e-1)" "unprognostic (5.53e-2)" "unprognostic (2.35e-3)" "unprognostic (1.48e-1)" "unprognostic (2.73e-2)" "unprognostic (9.61e-2)" "unprognostic (8.40e-8)" "unprognostic (2.03e-2)" "unprognostic (2.03e-1)" "unprognostic (1.41e-1)" "unprognostic (1.23e-1)" AFM "ALB2, ALBA" ENSG00000079557 Afamin P43652 4 73481745-73504001 "Plasma proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 932.0" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 294.0" "Cancer enriched" "Detected in single" 167 "liver cancer: 62.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA017006, HPA052437" Enhanced Uncertain "Plasma membrane" "Secreted to blood" Transport NA NA 54900000000 8700000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 55: Lymphoma - Immune response" "Cluster 43: Hepatocytes - Metabolism" 1 "Plasma membrane" "HPA017006: AB_1844635, HPA052437: AB_2732575" "prognostic favorable (1.80e-4)" "unprognostic (5.73e-2)" "unprognostic (4.24e-2)" AFP "FETA, HPAFP" ENSG00000081051 "Alpha fetoprotein" P02771 4 73431138-73456174 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "liver: 3.6" "Group enriched" "Detected in some" 7 "Extravillous trophoblasts: 87.4;Hepatocytes: 131.6;Proximal tubular cells: 124.1" "Cancer enriched" "Detected in some" 4 "liver cancer: 208.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "liver cancer: 642.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010607, HPA023600, CAB024283, CAB025339, CAB080122" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" "No annotated function" NA NA 3010000 150000000 "Cluster 83: Liver - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Golgi apparatus" Cytosol "CAB024283: AB_2650473, CAB025339: , CAB080122: , HPA010607: AB_1078141, HPA023600: AB_1844769" "unprognostic (4.69e-1)" "unprognostic (1.87e-1)" "unprognostic (3.34e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-3)" "unprognostic (2.95e-2)" "unprognostic (3.35e-1)" "unprognostic (1.54e-1)" "unprognostic (3.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.63e-6)" "unprognostic (1.98e-2)" "unprognostic (5.80e-2)" "unprognostic (1.14e-1)" AGA ASRG ENSG00000038002 Aspartylglucosaminidase P20933 4 177430774-177442437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031415, HPA031417" Enhanced "Intracellular and membrane" Enzyme NA NA 36000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 53: Non-specific - Glycosylation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 3 "HPA031415: AB_10603578, HPA031417: AB_10670967" "unprognostic (8.76e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-3)" "unprognostic (2.11e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (8.61e-4)" "prognostic unfavorable (1.99e-4)" "unprognostic (3.79e-1)" "unprognostic (6.44e-2)" "unprognostic (4.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.09e-1)" "unprognostic (7.49e-2)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (7.42e-2)" "unprognostic (1.47e-2)" AGER "RAGE, SCARJ1, sRAGE" ENSG00000204305 "Advanced glycosylation end-product specific receptor" Q15109 6 32180968-32184322 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lung: 704.7" "Cell type enriched" "Detected in many" 21 "Alveolar cells type 1: 2481.0" "Cancer enhanced" "Detected in all" "lung cancer: 27.2;thyroid cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.2" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB011682, HPA064436, HPA069474" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cell Junctions" "Secreted in other tissues" Other NA NA 5360000 100000 "Cluster 57: Lung - Lung function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" 12 "Plasma membrane, Cell Junctions" "Nucleoli fibrillar center" "CAB011682: AB_2258049, HPA064436: AB_2685264, HPA069474: " "unprognostic (9.37e-2)" "unprognostic (3.70e-1)" "unprognostic (2.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.55e-2)" "unprognostic (1.59e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (4.38e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.01e-7)" "unprognostic (3.57e-1)" "unprognostic (3.70e-2)" "unprognostic (4.44e-2)" "prognostic favorable (2.74e-6)" AGGF1 "FLJ10283, GPATC7, GPATCH7, HSU84971, VG5Q" ENSG00000164252 "Angiogenic factor with G-patch and FHA domains 1" Q8N302 5 77029251-77065234 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" "Developmental protein" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 49: Non-specific - Transcription" 4 "unprognostic (7.13e-2)" "unprognostic (1.04e-1)" "prognostic favorable (2.87e-4)" "unprognostic (1.67e-1)" "unprognostic (1.82e-1)" "unprognostic (6.52e-2)" "unprognostic (1.12e-3)" "unprognostic (4.27e-2)" "unprognostic (2.02e-2)" "unprognostic (4.03e-2)" "unprognostic (1.82e-2)" "unprognostic (4.04e-1)" "unprognostic (1.58e-3)" "unprognostic (2.10e-1)" "unprognostic (1.35e-1)" "unprognostic (3.30e-1)" "unprognostic (8.21e-2)" AGK "FLJ10842, MULK" ENSG00000006530 "Acylglycerol kinase" Q53H12 7 141551278-141655244 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Cardiomyopathy, Cataract, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 69.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 97.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020959, HPA053471" Supported Supported Vesicles,Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 19: NK-cells - Adaptive immune response" 1 Mitochondria Vesicles "HPA020959: AB_1854206, HPA053471: AB_2682164" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.28e-2)" "unprognostic (9.47e-3)" "unprognostic (5.43e-2)" "unprognostic (2.15e-2)" "unprognostic (3.68e-2)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (6.24e-3)" "unprognostic (7.90e-2)" "unprognostic (9.29e-2)" "unprognostic (9.65e-2)" "unprognostic (3.30e-1)" "unprognostic (1.18e-1)" AGPS "ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY" ENSG00000018510 "Alkylglycerone phosphate synthase" O00116 2 177392746-177567024 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cataract, Disease variant, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030209, HPA030210, HPA030211" Supported Enhanced Peroxisomes "Intracellular and membrane" Enzyme NA NA 69000 "Cluster 25: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 30: White matter - Myelination" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 18: Early spermatids - Unknown function" 1 Peroxisomes "HPA030209: AB_10600634, HPA030210: AB_10600202, HPA030211: AB_10602195" "unprognostic (7.10e-2)" "unprognostic (1.20e-2)" "unprognostic (1.76e-3)" "unprognostic (3.79e-2)" "unprognostic (8.34e-2)" "unprognostic (3.78e-2)" "prognostic unfavorable (8.62e-6)" "unprognostic (1.23e-2)" "unprognostic (7.23e-2)" "unprognostic (5.41e-2)" "prognostic unfavorable (8.35e-4)" "unprognostic (7.74e-2)" "prognostic favorable (9.45e-4)" "unprognostic (7.18e-2)" "unprognostic (3.46e-1)" "unprognostic (4.94e-3)" "unprognostic (1.92e-2)" AGR2 "AG2, HAG-2, PDIA17, XAG-2" ENSG00000106541 "Anterior gradient 2, protein disulphide isomerase family member" O95994 7 16791811-16833433 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 615.9;intestine: 1184.3;stomach 1: 1365.8" "Cell type enhanced" "Detected in many" "Club cells: 1768.3;Distal enterocytes: 1389.8;Enteroendocrine cells: 1388.6;Gastric mucus-secreting cells: 2597.0;Intestinal goblet cells: 7831.2;Undifferentiated cells: 1511.5" "Cancer enhanced" "Detected in many" "stomach cancer: 475.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 605.6;Gastric cancer: 837.5" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007912 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 38000 "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 62 "Endoplasmic reticulum" "HPA007912: AB_1844879" "unprognostic (6.19e-2)" "unprognostic (1.91e-1)" "unprognostic (9.05e-2)" "unprognostic (2.59e-2)" "unprognostic (2.23e-1)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.49e-2)" "unprognostic (1.84e-1)" "unprognostic (1.08e-2)" "unprognostic (3.24e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (8.79e-5)" "unprognostic (6.98e-2)" "unprognostic (2.38e-1)" "unprognostic (2.38e-1)" "unprognostic (3.22e-3)" AGR3 "BCMP11, hAG-3, HAG3, PDIA18" ENSG00000173467 "Anterior gradient 3, protein disulphide isomerase family member" Q8TD06 7 16859412-16881987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 217.5;intestine: 230.7;lung: 147.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 316.3;Ciliated cells: 1021.0;Distal enterocytes: 365.9;Enteroendocrine cells: 327.6;Intestinal goblet cells: 689.4;Ionocytes: 347.5;Paneth cells: 692.8;Proximal enterocytes: 1057.5;Undifferentiated cells: 404.6" "Cancer enhanced" "Detected in many" "breast cancer: 104.5" "Region enhanced" "Detected in some" "midbrain: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "breast cancer: 51.8;colorectal cancer: 65.3;Gastric cancer: 151.5" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enriched" "Detected in some" 5 "olfactory bulb: 4.6" HPA053942 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 67000 "Cluster 45: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 21 "Endoplasmic reticulum" Vesicles "HPA053942: AB_2682317" "unprognostic (2.18e-2)" "unprognostic (2.02e-1)" "unprognostic (2.13e-1)" "unprognostic (9.59e-2)" "unprognostic (3.32e-3)" "unprognostic (3.08e-2)" "unprognostic (1.49e-1)" "unprognostic (1.46e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-1)" "unprognostic (8.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.96e-1)" "unprognostic (6.66e-2)" "unprognostic (1.57e-1)" AGRN AGRIN ENSG00000188157 Agrin O00468 1 1020120-1056118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Differentiation "Developmental protein" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.7;Collecting duct cells: 89.5;Ductal cells: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040090 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Developmental protein" NA NA 20000000 "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 1 Cytosol "Plasma membrane" "HPA040090: AB_10805603" "unprognostic (8.04e-2)" "unprognostic (8.25e-3)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.82e-3)" "unprognostic (1.32e-1)" "unprognostic (3.33e-2)" "unprognostic (9.49e-3)" "unprognostic (1.06e-1)" "unprognostic (8.46e-2)" "unprognostic (8.49e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-1)" "unprognostic (1.31e-2)" AGRP "Agrt, ART, ASIP2" ENSG00000159723 "Agouti related neuropeptide" O00253 16 67482571-67483547 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 12.0;brain: 23.0;epididymis: 36.2" "Group enriched" "Detected in some" 4 "Distal tubular cells: 6.1;Hofbauer cells: 8.0;Leydig cells: 3.0;Macrophages: 5.4;Peritubular cells: 2.8" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in all" 30 "hypothalamus: 255.7" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Leukemia: 1.1;lymphoma: 1.3" "Lung - Macrophages" "Region enriched" "Detected in single" 16 "hypothalamus: 16.0" "Region enhanced" "Detected in single" "hypothalamus: 2.0" HPA041017 Enhanced Supported "Secreted in brain" "No annotated function" NA NA 255000 "Cluster 21: Neutrophils - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 35: RS4;11 - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA041017: AB_10795498" "unprognostic (1.32e-1)" "unprognostic (6.26e-2)" "unprognostic (1.13e-1)" "unprognostic (4.16e-1)" "unprognostic (3.15e-1)" "unprognostic (1.10e-1)" "unprognostic (3.61e-1)" "unprognostic (3.34e-1)" "unprognostic (4.68e-1)" "unprognostic (1.29e-1)" "unprognostic (6.74e-2)" "unprognostic (3.17e-1)" "unprognostic (2.80e-1)" "unprognostic (1.72e-1)" "unprognostic (5.63e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-2)" AGT SERPINA8 ENSG00000135744 Angiotensinogen P01019 1 230690776-230745576 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 1563.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 984.4;Hepatocytes: 1899.1" "Cancer enriched" "Detected in all" 4 "liver cancer: 1163.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "liver cancer: 204.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025798 Supported "Secreted to blood" Other NA NA 5940000 65000000000 "Cluster 83: Liver - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 8 "CAB025798: " "unprognostic (7.77e-2)" "unprognostic (4.46e-1)" "unprognostic (2.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.67e-1)" "unprognostic (3.61e-2)" "unprognostic (5.75e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (4.46e-2)" "unprognostic (4.32e-3)" "unprognostic (6.70e-2)" "unprognostic (9.28e-2)" "unprognostic (4.42e-3)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (1.38e-1)" AHSG "A2HS, FETUA, HSGA" ENSG00000145192 "Alpha 2-HS glycoprotein" P02765 3 186613060-186621318 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Mineral balance" "Cancer-related genes, Disease variant, Hypotrichosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4328 "liver: 5638.7" "Cell type enriched" "Detected in some" 14 "Hepatocytes: 1120.0" "Cancer enriched" "Detected in some" 284 "liver cancer: 1231.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "liver cancer: 479.5" "Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001524, HPA001525, CAB026209" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" Other NA NA 864000000000 110000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "Golgi apparatus" "CAB026209: , HPA001524: AB_1078851, HPA001525: AB_1078849" "unprognostic (6.40e-2)" "unprognostic (1.31e-1)" "unprognostic (2.03e-2)" "unprognostic (3.20e-2)" "unprognostic (1.07e-2)" "unprognostic (1.16e-2)" "unprognostic (7.47e-3)" "unprognostic (3.05e-1)" "unprognostic (5.27e-2)" "unprognostic (8.64e-2)" "unprognostic (3.99e-7)" "unprognostic (5.21e-2)" "unprognostic (5.21e-2)" "unprognostic (1.04e-1)" AIMP1 "EMAP-2, EMAPII, p43, SCYE1" ENSG00000164022 "Aminoacyl tRNA synthetase complex interacting multifunctional protein 1" Q12904 4 106315544-106349456 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Inflammatory response, Protein biosynthesis" "Cytokine, RNA-binding, tRNA-binding" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017618, HPA018476" Supported Enhanced Cytosol "Secreted to blood" Cytokine NA NA 6500000 35000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 56: Non-specific - Unknown function" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Mixed function" 2 Cytosol "CAB017618: AB_2285445, HPA018476: AB_1848137" "unprognostic (1.17e-3)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.29e-3)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "unprognostic (1.23e-2)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "unprognostic (7.13e-2)" "unprognostic (1.73e-1)" "unprognostic (2.27e-2)" AK4 "AK3, AK3L1" ENSG00000162433 "Adenylate kinase 4" P27144 1 65147549-65232145 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 174.9;liver: 99.2" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 149.3;Hepatocytes: 227.4;Proximal tubular cells: 514.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 3.1;myeloid DC: 2.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.7;monocytes: 3.1" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "HPA042753, HPA049461" Supported Supported Mitochondria "Intracellular and membrane" Enzyme NA Yes 39000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria "HPA042753: AB_2678146, HPA049461: AB_2680776" "unprognostic (3.73e-2)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.25e-1)" "unprognostic (3.05e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.83e-4)" "unprognostic (1.16e-3)" "unprognostic (3.89e-2)" "unprognostic (4.03e-1)" "unprognostic (5.39e-2)" "prognostic unfavorable (4.34e-5)" "unprognostic (6.71e-2)" "prognostic unfavorable (4.36e-4)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.69e-1)" "unprognostic (7.07e-2)" "unprognostic (7.57e-2)" AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 218.2;intestine: 597.0;stomach 1: 421.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 383.9;Cholangiocytes: 194.6;Distal enterocytes: 223.5;Gastric mucus-secreting cells: 493.5;Proximal enterocytes: 367.6;Suprabasal keratinocytes: 535.7" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Gallbladder cancer: 2714.5" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" Enzyme NA NA 67000000 "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" 2 Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" ALB ENSG00000163631 Albumin P02768 4 73397114-73421482 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 136 "liver: 205952.1" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 59612.0" "Cancer enriched" "Detected in many" 384 "liver cancer: 14213.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 24 "liver cancer: 1846.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB006262, HPA031024, HPA031025" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" Transport NA NA 40000000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 33: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "Golgi apparatus" "Endoplasmic reticulum" "CAB006262: AB_425297, HPA031024: AB_2673703, HPA031025: AB_2673704" "unprognostic (1.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.73e-1)" "unprognostic (2.60e-1)" "unprognostic (4.44e-1)" "unprognostic (2.46e-1)" "unprognostic (9.53e-3)" "unprognostic (2.16e-2)" "unprognostic (2.40e-1)" "unprognostic (6.43e-2)" "unprognostic (3.84e-2)" "unprognostic (5.37e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.87e-4)" "unprognostic (7.23e-2)" "unprognostic (1.05e-3)" "unprognostic (1.02e-2)" ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 424.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 292.6;Oligodendrocyte precursor cells: 638.2;Oligodendrocytes: 913.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Enteric glia cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" Immunity NA NA 1600000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 3 Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698562 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 282.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Breast glandular cells - Lactation" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" ALG1 "CDG1K, HMAT1, HMT-1, Mat-1" ENSG00000033011 "ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase" Q9BT22 16 5033702-5087379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060392 Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 46: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 54: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA060392: AB_2684273" "unprognostic (1.66e-2)" "unprognostic (5.18e-1)" "prognostic favorable (5.79e-4)" "unprognostic (1.55e-2)" "unprognostic (2.10e-2)" "unprognostic (3.22e-2)" "unprognostic (2.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (5.27e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (2.58e-3)" "unprognostic (3.86e-2)" ALKAL1 "AUGB, FAM150A, UNQ9433" ENSG00000196711 "ALK and LTK ligand 1" Q6UXT8 8 52534037-52565430 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.3;thyroid gland: 2.3;urinary bladder: 1.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 13.4;Distal tubular cells: 3.1;Mucus glandular cells: 3.4;Oocytes: 5.1;Paneth cells: 3.0;Salivary duct cells: 3.7;Secretory cells: 2.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 2.0" "Liver - Cholangiocyte, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027368 Uncertain "Secreted to blood" Cytokine NA NA "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 2 "HPA027368: AB_10602317" "unprognostic (1.18e-1)" "unprognostic (1.13e-4)" "unprognostic (9.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.52e-1)" "unprognostic (6.60e-2)" "unprognostic (1.70e-4)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (9.58e-3)" ALKAL2 "AUGA, FAM150B" ENSG00000189292 "ALK and LTK ligand 2" Q6UX46 2 279558-288851 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 198.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 122.1;Glandular and luminal cells: 49.5;Granulosa cells: 154.5;Ovarian stromal cells: 60.3;Spermatocytes: 52.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 5.7;lymphoma: 14.9" "Kidney - Proximal tubular cells, Liver - Cholangiocyte, Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "amygdala: 3.3;basal ganglia: 2.1;cerebral cortex: 1.7;hippocampal formation: 2.3;spinal cord: 1.0" "Secreted to blood" Cytokine NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "unprognostic (1.39e-3)" "unprognostic (1.44e-2)" "unprognostic (2.41e-2)" "unprognostic (2.03e-3)" "unprognostic (2.88e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.35e-1)" "unprognostic (9.29e-3)" "unprognostic (5.19e-2)" "unprognostic (3.68e-1)" ALKBH1 "ABH, alkB, ALKBH, hABH" ENSG00000100601 "AlkB homolog 1, histone H2A dioxygenase" Q13686 14 77672404-77708023 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, RNA repair, Translation regulation" "Dioxygenase, Lyase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044087, HPA060061" Approved Supported "Nucleoplasm,Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 44: Oocytes - Unknown function" Nucleoplasm "Endoplasmic reticulum" "HPA044087: AB_2678803, HPA060061: " "unprognostic (1.92e-2)" "unprognostic (8.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.37e-3)" "unprognostic (3.41e-2)" "unprognostic (5.03e-2)" "unprognostic (3.74e-3)" "unprognostic (7.45e-3)" "unprognostic (2.68e-2)" "unprognostic (3.95e-2)" "unprognostic (5.05e-3)" "unprognostic (2.16e-2)" "prognostic favorable (1.80e-4)" "unprognostic (1.65e-3)" "unprognostic (1.46e-1)" "unprognostic (2.63e-1)" "unprognostic (2.44e-2)" ALPG "ALPPL2, GCAP" ENSG00000163286 "Alkaline phosphatase, germ cell" P10696 2 232406844-232410714 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal enterocytes: 2.3;Spermatogonia: 1.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 49.1;testis cancer: 64.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 20.0;testis cancer: 35.3" "CAB020698, HPA038764, HPA038765, HPA051699" Approved Approved "Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" "CAB020698: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.39e-1)" "unprognostic (6.63e-3)" "unprognostic (1.27e-2)" "unprognostic (2.89e-1)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.69e-3)" "unprognostic (1.65e-1)" "unprognostic (2.67e-1)" "unprognostic (6.72e-3)" ALPI IAP ENSG00000163295 "Alkaline phosphatase, intestinal" P09923 2 232456125-232460753 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 139 "intestine: 137.3" "Cell type enriched" "Detected in some" 9 "Proximal enterocytes: 291.6" "Cancer enhanced" "Detected in many" "liver cancer: 4.7;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes" "HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" Enzyme NA NA 130000 "Cluster 25: Small intestine - Absorption" "Cluster 34: Testis cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 3 "Plasma membrane" "HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.01e-1)" "unprognostic (7.71e-2)" "unprognostic (4.14e-2)" "unprognostic (1.47e-1)" "unprognostic (9.57e-4)" "unprognostic (8.07e-2)" "unprognostic (1.71e-1)" "unprognostic (9.99e-2)" ALPL "HOPS, TNALP, TNAP, TNSALP" ENSG00000162551 "Alkaline phosphatase, biomineralization associated" P05186 1 21509397-21578410 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 58.8" "Cell type enriched" "Detected in many" 7 "Alveolar cells type 2: 315.4" "Cancer enhanced" "Detected in all" "testis cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 90 "neutrophil: 381.2" "Lineage enriched" "Detected in many" 139 "granulocytes: 381.2" "Cancer enhanced" "Detected in many" "Bone cancer: 75.0;testis cancer: 44.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Neutrophils, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" Enzyme NA NA 13000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 72: Alveolar cells - Lung function" 1 Cytosol "CAB020829: , HPA007105: AB_1078137, HPA008765: AB_1078138" "unprognostic (3.89e-2)" "unprognostic (1.27e-1)" "unprognostic (5.57e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.05e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (7.08e-4)" "unprognostic (1.17e-2)" "unprognostic (2.48e-3)" "unprognostic (1.74e-1)" "unprognostic (7.28e-2)" "unprognostic (1.73e-2)" "unprognostic (2.27e-1)" "unprognostic (9.70e-3)" "unprognostic (2.58e-1)" ALPP "PALP, PLAP" ENSG00000163283 "Alkaline phosphatase, placental" P05187 2 232378724-232382889 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 17.2;placenta: 33.6" "Cell type enriched" "Detected in some" 9 "Alveolar cells type 1: 57.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 48.0;Gastric cancer: 52.3" "CAB026327, HPA038764, HPA038765, HPA051699" Enhanced Approved "Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 30 "Plasma membrane" "CAB026327: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (4.86e-2)" "unprognostic (5.19e-3)" "unprognostic (6.67e-3)" "unprognostic (2.60e-1)" "unprognostic (2.44e-3)" "unprognostic (1.26e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-2)" AMBN ENSG00000178522 Ameloblastin Q9NP70 4 70592256-70607288 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.8" "Cell type enhanced" "Detected in single" "Microglial cells: 1.8" "Group enriched" "Detected in some" 7 "cervical cancer: 2.6;endometrial cancer: 2.9" "Region enhanced" "Detected in single" "basal ganglia: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 2.5;Rhabdoid: 7.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036099 Uncertain Nucleoplasm,Vesicles "Secreted in other tissues" Other NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 5 Vesicles Nucleoplasm "HPA036099: " "unprognostic (3.22e-1)" AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Oxidoreductase, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10607.0" "Group enriched" "Detected in many" 23 "Cholangiocytes: 2459.2;Hepatocytes: 9092.4" "Cancer enriched" "Detected in many" 115 "liver cancer: 2620.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "liver cancer: 556.5" "Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" Enzyme NA NA 47000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 2 Vesicles "Golgi apparatus, Cytosol" "CAB069436: AB_1611916, HPA001497: AB_1078144, HPA075585: " "unprognostic (6.92e-2)" "unprognostic (3.61e-1)" "unprognostic (4.95e-3)" "prognostic favorable (1.20e-4)" "unprognostic (9.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-3)" "unprognostic (7.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (7.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.89e-3)" "unprognostic (4.66e-2)" "unprognostic (2.97e-3)" "unprognostic (9.45e-3)" AMELX "AIH1, AMG" ENSG00000125363 "Amelogenin X-linked" Q99217 X 11293413-11300761 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "urothelial cancer: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Other NA NA "Cluster 44: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "unprognostic (1.76e-1)" "unprognostic (1.00e-1)" "unprognostic (2.00e-1)" AMELY AMGL ENSG00000099721 "Amelogenin Y-linked" Q99218 Y 6865918-6911752 "Predicted secreted proteins" Biomineralization "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" Other NA NA "Cluster 24: Cytotrophoblasts - Mitochondria" "unprognostic (1.62e-1)" AMH "MIF, MIS" ENSG00000104899 "Anti-Mullerian hormone" P03971 19 2249309-2252073 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Gonadal differentiation" "Growth factor" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.4;pituitary gland: 3.8;testis: 10.2" "Group enriched" "Detected in some" 29 "Granulosa cells: 368.4;Sertoli cells: 345.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA066973 Approved Vesicles,Aggresome "Secreted to blood" "Growth factor" NA NA 1580000 280000 "Cluster 78: Testis - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 6: Ovarian stromal cells - Transcription" "Vesicles, Aggresome" "HPA066973: AB_2732754" "unprognostic (8.10e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.21e-5)" "unprognostic (8.73e-3)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "unprognostic (8.03e-2)" "unprognostic (8.99e-2)" "unprognostic (2.55e-1)" "unprognostic (3.53e-1)" "unprognostic (5.95e-3)" "unprognostic (1.34e-2)" "unprognostic (8.73e-8)" "unprognostic (4.64e-2)" "unprognostic (4.14e-2)" "unprognostic (2.15e-1)" "unprognostic (2.76e-1)" AMN amnionless ENSG00000166126 "Amnion associated transmembrane protein" Q9BXJ7 14 102922663-102933596 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protein transport, Transport" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 81.3;kidney: 38.7;liver: 36.9" "Group enriched" "Detected in many" 4 "Distal enterocytes: 671.4;Proximal enterocytes: 1890.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.1;Gastric cancer: 6.2;liver cancer: 6.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA000817 Approved "Secreted in other tissues" Transport NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA000817: AB_1078146" "unprognostic (2.02e-2)" "unprognostic (1.67e-1)" "unprognostic (3.94e-3)" "unprognostic (7.39e-3)" "unprognostic (9.32e-2)" "unprognostic (1.88e-3)" "unprognostic (8.68e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (2.97e-2)" "unprognostic (7.57e-2)" "unprognostic (2.43e-2)" "prognostic favorable (9.62e-5)" "unprognostic (8.02e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" AMTN "RSTI689, UNQ689" ENSG00000187689 Amelotin Q6UX39 4 70518569-70532743 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 27.5;salivary gland: 6.6;stomach 1: 7.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 11.1;Mucus glandular cells: 32.7;Salivary duct cells: 46.6" "Group enriched" "Detected in many" 11 "cervical cancer: 13.9;head and neck cancer: 38.3;lung cancer: 12.7" "Region enhanced" "Detected in single" "white matter: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.6;liver cancer: 11.1;Uterine cancer: 15.5" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036136, HPA036137" Uncertain "Secreted in other tissues" "Cell adhesion" NA NA "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA036136: AB_2674963, HPA036137: AB_10673614" "unprognostic (1.72e-1)" "unprognostic (2.47e-1)" "unprognostic (2.04e-1)" "unprognostic (2.36e-1)" "unprognostic (3.80e-1)" "unprognostic (1.52e-1)" "unprognostic (1.86e-2)" "unprognostic (7.35e-2)" "unprognostic (2.55e-2)" AMY1A AMY1 ENSG00000237763 "Amylase alpha 1A" P0DUB6 1 103655760-103664554 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 308 "salivary gland: 8032.9" "Cell type enriched" "Detected in some" 40 "Serous glandular cells: 53.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "CAB004310, HPA045394, HPA045399, HPA046980" Enhanced "Secreted to digestive system" Enzyme NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 75: Serous glandular cells - Salivary secretion" "CAB004310: AB_626668, HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" AMY1B AMY1 ENSG00000174876 "Amylase alpha 1B" P0DTE7 1 103687415-103696454 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 97 "salivary gland: 10157.7" "Cell type enriched" "Detected in some" 33 "Serous glandular cells: 70.0" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" Enzyme NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (7.34e-2)" "unprognostic (2.59e-1)" "unprognostic (6.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.96e-1)" AMY1C AMY1 ENSG00000187733 "Amylase alpha 1C" P0DTE8 1 103745323-103758726 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 66 "salivary gland: 8146.9" "Cell type enriched" "Detected in single" 33 "Serous glandular cells: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" Enzyme NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" AMY2A AMY2 ENSG00000243480 "Amylase alpha 2A" P04746 1 103617427-103625780 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4638 "pancreas: 148982.6" "Cell type enriched" "Detected in some" 135 "Exocrine glandular cells: 251.1" "Cancer enriched" "Detected in single" 2010 "pancreatic cancer: 200.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, CAB045960, HPA046980" Enhanced "Secreted to digestive system" Enzyme NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "CAB045960: AB_2226891, HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (3.27e-1)" "unprognostic (1.78e-3)" "unprognostic (3.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.13e-2)" AMY2B AMY2 ENSG00000240038 "Amylase alpha 2B" P19961 1 103553815-103579534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 128 "pancreas: 33913.0" "Cell type enriched" "Detected in many" 7 "Serous glandular cells: 471.9" "Cancer enriched" "Detected in many" 15 "pancreatic cancer: 25.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 5.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Pancreas - Exocrine glandular cells" "HPA045394, HPA045399, HPA046980" Supported "Secreted to digestive system" Enzyme NA NA 77000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 15: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA045394: AB_2679311, HPA045399: AB_2679313, HPA046980: AB_2679889" "unprognostic (8.69e-4)" "unprognostic (3.71e-3)" "unprognostic (6.41e-2)" "unprognostic (9.75e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-4)" "unprognostic (1.21e-2)" "unprognostic (1.63e-2)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-2)" "unprognostic (7.41e-3)" "unprognostic (1.55e-2)" "unprognostic (5.74e-2)" "unprognostic (4.22e-1)" "unprognostic (3.12e-4)" ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 2920.4" "Cell type enriched" "Detected in many" 25 "Hepatocytes: 5169.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.6;myeloid DC: 14.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" "Developmental protein" Yes No 308000000 410000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 31: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 5 "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" ANGEL1 "Ccr4e, KIAA0759" ENSG00000013523 "Angel homolog 1" Q9UNK9 14 76786009-76826246 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 65.5;Late spermatids: 74.5;Oligodendrocyte precursor cells: 60.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000948 Uncertain Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 46: Testis - Spermatogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoplasm "HPA000948: AB_2227189" "unprognostic (4.81e-2)" "unprognostic (2.37e-2)" "unprognostic (2.67e-1)" "unprognostic (2.46e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-1)" "unprognostic (7.33e-2)" "prognostic favorable (3.43e-4)" "unprognostic (9.24e-2)" "unprognostic (1.01e-1)" "prognostic favorable (5.46e-4)" "unprognostic (3.03e-1)" "unprognostic (6.92e-3)" "unprognostic (1.42e-1)" "unprognostic (2.22e-1)" "unprognostic (1.53e-1)" "unprognostic (6.32e-2)" ANGPT1 "AGPT-1, Ang1, KIAA0003" ENSG00000154188 "Angiopoietin 1" Q15389 8 107249482-107498055 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 32.5" "Cell type enhanced" "Detected in many" "Astrocytes: 57.3;Fibroblasts: 29.7;Inhibitory neurons: 36.1;Serous glandular cells: 36.7;Smooth muscle cells: 51.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.8" "Cancer enhanced" "Detected in many" "Rhabdoid: 45.3" "Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017815, HPA018793, HPA018816" Approved "Secreted to blood" "Developmental protein" NA NA 32000000 110000 "Cluster 28: Neutrophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "CAB017815: , HPA018793: AB_1844820, HPA018816: AB_1844821" "unprognostic (7.71e-2)" "unprognostic (2.13e-1)" "unprognostic (6.37e-2)" "unprognostic (4.11e-3)" "unprognostic (7.36e-2)" "unprognostic (3.80e-2)" "unprognostic (2.22e-3)" "unprognostic (3.29e-2)" "unprognostic (1.07e-2)" "unprognostic (5.54e-2)" "unprognostic (2.62e-1)" "unprognostic (1.44e-1)" "prognostic favorable (4.40e-4)" "unprognostic (4.56e-3)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Lymphatic endothelial cells: 498.2" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.4" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" "Developmental protein" NA NA 3780000 110000 "Cluster 34: B-cells - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 1 "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" ANGPT4 ENSG00000101280 "Angiopoietin 4" Q9Y264 20 869900-916334 "Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.9;breast: 6.3" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 61.2;Late spermatids: 17.5;Smooth muscle cells: 14.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013260, CAB013305" Uncertain "Secreted to blood" "Developmental protein" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" "CAB013260: , CAB013305: " "unprognostic (1.77e-1)" "unprognostic (3.25e-1)" "unprognostic (4.30e-2)" "unprognostic (1.04e-3)" "unprognostic (6.37e-2)" "unprognostic (3.41e-1)" "unprognostic (5.82e-4)" "unprognostic (1.25e-1)" "unprognostic (7.10e-2)" "unprognostic (3.66e-4)" "unprognostic (9.01e-2)" "unprognostic (1.71e-1)" "unprognostic (5.25e-2)" "unprognostic (1.23e-2)" "unprognostic (1.55e-1)" "unprognostic (2.95e-4)" "unprognostic (9.14e-2)" ANGPTL1 "ANG3, ANGPT3, AngY, ARP1" ENSG00000116194 "Angiopoietin like 1" O95841 1 178849535-178871077 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 129.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 88.6;Leydig cells: 421.9;Ovarian stromal cells: 91.9;Peritubular cells: 205.9;Schwann cells: 92.9;Smooth muscle cells: 81.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.1" "Kidney - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009976 Approved "Secreted to blood" "No annotated function" NA NA 380000 "Cluster 34: B-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA009976: AB_1844822" "unprognostic (2.59e-2)" "unprognostic (1.31e-1)" "unprognostic (5.80e-3)" "unprognostic (2.63e-2)" "unprognostic (3.60e-1)" "unprognostic (1.71e-2)" "prognostic favorable (8.73e-4)" "unprognostic (3.81e-2)" "unprognostic (5.78e-3)" "unprognostic (1.47e-1)" "unprognostic (1.39e-1)" "unprognostic (5.31e-2)" "prognostic favorable (5.11e-4)" "unprognostic (1.49e-2)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.61e-3)" ANGPTL2 "ARP2, HARP" ENSG00000136859 "Angiopoietin like 2" Q9UKU9 9 127087348-127122635 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 38.0;Fibroblasts: 77.1;Mesothelial cells: 30.7;Oligodendrocyte precursor cells: 33.0;Skeletal myocytes: 35.1;Smooth muscle cells: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 24.6" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040933, HPA041299" Approved Approved "Golgi apparatus" "Secreted to blood" "No annotated function" NA NA 2510000 2200000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Golgi apparatus" "HPA040933: AB_10795530, HPA041299: AB_10794552" "unprognostic (5.46e-2)" "unprognostic (4.96e-3)" "unprognostic (1.11e-2)" "unprognostic (2.07e-2)" "unprognostic (8.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.79e-2)" "unprognostic (2.04e-2)" "unprognostic (3.31e-1)" "unprognostic (1.17e-3)" "unprognostic (2.34e-2)" "unprognostic (1.80e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-2)" "unprognostic (4.15e-2)" ANGPTL3 ANGPT5 ENSG00000132855 "Angiopoietin like 3" Q9Y5C1 1 62597520-62606313 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Lipid metabolism" Heparin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 655.3" "Group enriched" "Detected in some" 22 "Hepatocytes: 694.2;Proximal tubular cells: 210.2" "Cancer enriched" "Detected in some" 39 "liver cancer: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 39 "liver cancer: 9.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038097 Approved "Secreted to blood" "Cell adhesion" NA NA 225000000 120000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "HPA038097: AB_10675628" "unprognostic (2.29e-1)" "unprognostic (8.01e-2)" "unprognostic (2.51e-1)" "unprognostic (4.06e-2)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (4.06e-2)" "unprognostic (1.56e-2)" "unprognostic (8.11e-3)" "unprognostic (6.85e-3)" "unprognostic (2.89e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.09e-2)" "unprognostic (5.38e-2)" "unprognostic (7.62e-2)" ANGPTL4 "ARP4, FIAF, HFARP, NL2, PGAR, pp1158" ENSG00000167772 "Angiopoietin like 4" Q9BY76 19 8363289-8374370 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 189.6;breast: 159.7;liver: 179.2" "Cell type enhanced" "Detected in many" "Astrocytes: 121.4;Basal respiratory cells: 282.3;Extravillous trophoblasts: 132.6;Hepatocytes: 116.3;Peritubular cells: 127.0" "Cancer enriched" "Detected in all" 4 "renal cancer: 212.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 3.3" "Lineage enriched" "Detected in single" 11 "granulocytes: 3.3" "Cancer enhanced" "Detected in many" "Kidney cancer: 78.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA007879, CAB033770" Approved Approved Nucleoplasm,Vesicles "Secreted to blood" "Developmental protein" NA NA 7750000 3100000 "Cluster 11: Liver - Plasma proteins" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 2 "Nucleoplasm, Vesicles" "CAB033770: AB_2057427, HPA007879: AB_1078158" "unprognostic (1.26e-1)" "unprognostic (5.29e-3)" "prognostic unfavorable (7.53e-4)" "unprognostic (1.88e-2)" "unprognostic (7.68e-3)" "unprognostic (3.58e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (3.18e-1)" "unprognostic (3.90e-3)" "unprognostic (9.69e-3)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.34e-5)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.00e-2)" ANGPTL5 ENSG00000187151 "Angiopoietin like 5" Q86XS5 11 101890674-101916522 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.3;ovary: 19.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 16.1;Leydig cells: 26.3;Ovarian stromal cells: 70.8;Peritubular cells: 15.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Fibroblasts, Heart muscle - Fibroblasts, Thyroid - Fibroblasts" "Region enhanced" "Detected in some" "spinal cord: 4.3" HPA038516 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 6: Ovarian stromal cells - Transcription" 1 "HPA038516: AB_10672749" "unprognostic (8.28e-3)" "unprognostic (3.08e-2)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (3.23e-2)" "unprognostic (2.18e-1)" "unprognostic (4.88e-2)" "unprognostic (6.74e-4)" "unprognostic (1.96e-1)" "unprognostic (1.53e-8)" "unprognostic (3.40e-2)" "unprognostic (1.95e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-3)" ANGPTL6 "AGF, ARP5" ENSG00000130812 "Angiopoietin like 6" Q8NI99 19 10092338-10102678 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 29.4" "Cell type enriched" "Detected in some" 10 "Granulosa cells: 109.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Leukemia: 13.2;lymphoma: 6.5" "Liver - Hepatic stellate cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" "Developmental protein" NA NA 450000 23000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 83: Liver - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 15: Non-specific - Mixed function" "unprognostic (1.28e-1)" "unprognostic (2.18e-6)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-1)" "unprognostic (1.02e-2)" "unprognostic (8.77e-2)" "unprognostic (5.25e-2)" "unprognostic (1.00e-1)" "unprognostic (2.99e-2)" "unprognostic (1.23e-2)" "unprognostic (1.85e-1)" "unprognostic (2.26e-10)" "unprognostic (8.96e-2)" "unprognostic (4.41e-2)" "unprognostic (1.25e-2)" "unprognostic (1.32e-1)" ANGPTL7 "AngX, CDT6" ENSG00000171819 "Angiopoietin like 7" O43827 1 11189355-11195981 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.4" "Cell type enriched" "Detected in some" 4 "Schwann cells: 74.5" "Cancer enriched" "Detected in some" 14 "melanoma: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Enteric glia cells" "Not detected" "Not detected" "Region enriched" "Detected in all" 13 "spinal cord: 82.5" "Secreted in other tissues" "No annotated function" NA NA 1100000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 1 "unprognostic (3.23e-2)" "unprognostic (6.95e-2)" "unprognostic (1.22e-1)" "unprognostic (2.67e-3)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.89e-2)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (3.97e-1)" "unprognostic (1.10e-1)" "unprognostic (1.58e-2)" "unprognostic (3.41e-3)" "unprognostic (1.92e-1)" "unprognostic (1.19e-3)" "unprognostic (2.49e-2)" ANGPTL8 "C19orf80, RIFL, TD26" ENSG00000130173 "Angiopoietin like 8" Q6UXH0 19 11237450-11241943 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Hormone "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "liver: 399.9" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 124.8" "Cancer enriched" "Detected in some" 37 "liver cancer: 84.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "liver cancer: 9.6" "Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Not detected" "Not detected" HPA042131 Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" Hormone NA NA 836000 350000 "Cluster 83: Liver - Metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 1 "Golgi apparatus" Nucleoplasm "HPA042131: AB_10794413" "unprognostic (2.37e-2)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (1.31e-2)" "unprognostic (1.17e-1)" "unprognostic (1.00e-1)" "unprognostic (3.73e-1)" "unprognostic (2.80e-1)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" "unprognostic (9.67e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (4.57e-1)" "unprognostic (1.75e-2)" ANK1 "ANK, SPH1" ENSG00000029534 "Ankyrin 1" P16157 8 41653220-41896741 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 950.3;tongue: 609.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 193.0;Cone photoreceptor cells: 54.4;Erythroid cells: 167.2;Horizontal cells: 84.3;Inhibitory neurons: 170.0;Skeletal myocytes: 220.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 9.5;naive B-cell: 7.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 44.6" "Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Erythroid cells, Pancreas - Beta cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004842, HPA056953" Supported Supported "Intracellular and membrane" "No annotated function" NA NA 4200000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA004842: AB_1844827, HPA056953: AB_2683284" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (4.22e-3)" "unprognostic (2.31e-3)" "unprognostic (1.76e-7)" "unprognostic (2.03e-1)" "unprognostic (2.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.95e-1)" "unprognostic (3.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (3.86e-1)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" ANKDD1A FLJ25870 ENSG00000166839 "Ankyrin repeat and death domain containing 1A" Q495B1 15 64911902-64958691 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 8.6" "Cell type enhanced" "Detected in many" "Astrocytes: 198.8;Leydig cells: 60.8;Peritubular cells: 77.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 10.0" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in some" "Region enriched" "Detected in all" 5 "cerebellum: 16.2" HPA040757 Approved Approved Nucleoplasm "Secreted - unknown location" "No annotated function" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 47: Astrocytes - Unknown function" Nucleoplasm "HPA040757: AB_10960566" "unprognostic (3.72e-4)" "unprognostic (1.86e-1)" "unprognostic (6.07e-3)" "unprognostic (3.25e-2)" "unprognostic (4.78e-1)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-3)" "unprognostic (5.11e-3)" "unprognostic (5.57e-2)" "unprognostic (4.37e-2)" "unprognostic (1.60e-1)" "unprognostic (3.15e-7)" "unprognostic (1.06e-1)" "unprognostic (1.98e-1)" "unprognostic (8.04e-3)" "unprognostic (1.64e-2)" ANOS1 "ADMLX, KAL, KAL1, KALIG-1, WFDC19" ENSG00000011201 "Anosmin 1" P23352 X 8528874-8732137 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 41.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 107.0;Astrocytes: 62.2;Inhibitory neurons: 26.9;Microglial cells: 25.9;Oligodendrocyte precursor cells: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 15.1" "Colon - Enteric glia cells, Lung - Alveolar cells type 1, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Secreted in brain" "Cell adhesion" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 22: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 25: Bipolar cells - Visual perception" 3 "unprognostic (2.93e-1)" "unprognostic (5.33e-2)" "unprognostic (9.54e-2)" "unprognostic (4.16e-3)" "unprognostic (7.77e-3)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" "unprognostic (1.17e-3)" "unprognostic (4.53e-2)" "unprognostic (6.43e-2)" "unprognostic (2.09e-2)" "unprognostic (6.24e-2)" "unprognostic (1.71e-2)" "unprognostic (9.38e-3)" "unprognostic (6.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.56e-2)" ANTXR1 "ATR, FLJ10601, FLJ21776, TEM8" ENSG00000169604 "ANTXR cell adhesion molecule 1" Q9H6X2 2 69013176-69249327 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor Hypotrichosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 123.9;Endometrial stromal cells: 81.6;Oligodendrocyte precursor cells: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 349.2" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054785 Uncertain Vesicles "Intracellular and membrane" Receptor NA NA 11000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" Vesicles "HPA054785: " "unprognostic (1.44e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (8.49e-2)" "unprognostic (4.77e-2)" "unprognostic (3.61e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (4.15e-3)" "unprognostic (9.05e-3)" "unprognostic (1.15e-1)" "unprognostic (3.48e-3)" "unprognostic (2.26e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (1.22e-5)" "unprognostic (2.09e-2)" ANTXR2 "CMG-2, CMG2, FLJ31074" ENSG00000163297 "ANTXR cell adhesion molecule 2" P58335 4 79901146-80125454 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 78.8;Schwann cells: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Kidney - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA 13000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 53: Fibroblasts - ECM organization" 2 "unprognostic (3.01e-1)" "unprognostic (1.79e-2)" "unprognostic (1.95e-2)" "unprognostic (4.87e-2)" "unprognostic (5.63e-2)" "unprognostic (2.30e-2)" "unprognostic (6.75e-2)" "unprognostic (3.77e-2)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (1.27e-1)" "prognostic unfavorable (3.34e-6)" "unprognostic (1.03e-3)" "unprognostic (2.98e-2)" "unprognostic (1.10e-2)" "unprognostic (1.78e-1)" ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7281.3" "Cell type enhanced" "Detected in many" "granulocytes: 3470.5;Squamous epithelial cells: 3652.5;Suprabasal keratinocytes: 8372.3;Syncytiotrophoblasts: 8404.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2824.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693, CAB080415" Enhanced Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA Yes 3000000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" 6 "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear membrane" "CAB013023: AB_2533983, CAB035987: , CAB058693: AB_2665585, CAB080415: , HPA011271: AB_1844883, HPA011272: AB_1844884" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.08e-2)" "prognostic favorable (5.71e-5)" "unprognostic (1.53e-2)" "unprognostic (4.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-3)" "unprognostic (1.47e-1)" "unprognostic (9.82e-3)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "prognostic favorable (4.57e-5)" "prognostic unfavorable (6.19e-6)" ANXA2 "ANX2, ANX2L4, CAL1H, LIP2, LPC2D" ENSG00000182718 "Annexin A2" P07355 15 60347134-60402883 "Cancer-related genes, Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2124.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5295.0;Ductal cells: 3448.7;Pancreatic endocrine cells: 3363.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 4446.3;classical monocyte: 2767.4;intermediate monocyte: 2404.9;myeloid DC: 4023.2;non-classical monocyte: 2699.3;T-reg: 1686.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 213.0" "CAB004311, HPA046964, HPA061798" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" Other NA NA 19000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 9 "Plasma membrane" Cytosol "CAB004311: AB_626677, HPA046964: AB_2732537, HPA061798: AB_2732671" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "prognostic favorable (6.88e-5)" "unprognostic (4.06e-3)" "unprognostic (5.42e-3)" "prognostic unfavorable (2.54e-5)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.94e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (7.74e-2)" "unprognostic (2.55e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.59e-5)" AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.8;lymphoid tissue: 63.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 59.6;Kupffer cells: 109.7;Macrophages: 73.5;Microglial cells: 222.8;monocytes: 91.5;NK-cells: 99.3;T-cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "colorectal cancer: 4.5;Leukemia: 5.7;lymphoma: 5.7" "Breast - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Stomach - Macrophages, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021666, HPA026716" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" 1 Vesicles "Endoplasmic reticulum" "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" AOC1 "ABP, ABP1, DAO" ENSG00000002726 "Amine oxidase copper containing 1" P19801 7 150824627-150861504 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 221.1;kidney: 131.7;placenta: 479.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 241.2;Distal enterocytes: 377.7;Intestinal goblet cells: 116.8;Paneth cells: 304.1;Proximal enterocytes: 876.3" "Group enriched" "Detected in many" 5 "colorectal cancer: 61.3;endometrial cancer: 39.1;pancreatic cancer: 26.9;renal cancer: 69.4;stomach cancer: 43.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 12 "eosinophil: 31.3" "Lineage enriched" "Detected in many" 22 "granulocytes: 31.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 48.4" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031032, HPA031033" Approved "Secreted in other tissues" Enzyme NA NA 2500000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 45: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 8 "HPA031032: AB_10670150, HPA031033: AB_10669670" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.84e-2)" "unprognostic (6.31e-3)" "unprognostic (8.31e-3)" "unprognostic (9.07e-3)" "unprognostic (6.42e-2)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (3.11e-1)" "prognostic favorable (1.71e-4)" "unprognostic (5.32e-3)" "unprognostic (3.62e-2)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" AOC2 "DAO2, RAO" ENSG00000131480 "Amine oxidase copper containing 2" O75106 17 42844580-42850707 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Early spermatids: 12.3;Late spermatids: 18.5" "Cancer enhanced" "Detected in some" "testis cancer: 3.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057779 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 78: Testis - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 21: Early spermatids - Spermatogenesis" 2 "HPA057779: " "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (5.10e-4)" "unprognostic (1.90e-2)" "unprognostic (1.48e-2)" "unprognostic (2.42e-1)" "unprognostic (4.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.39e-1)" "unprognostic (3.64e-2)" "unprognostic (2.16e-2)" "unprognostic (8.27e-3)" "unprognostic (4.55e-5)" "unprognostic (3.55e-2)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.47e-4)" AOC3 "HPAO, VAP-1, VAP1" ENSG00000131471 "Amine oxidase copper containing 3" Q16853 17 42851184-42858130 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 408.1" "Cell type enhanced" "Detected in many" "Adipocytes: 56.3;Fibroblasts: 24.1;Peritubular cells: 69.7;Sertoli cells: 54.4;Smooth muscle cells: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000980, CAB025797" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted - unknown location" "Cell adhesion" NA NA 240000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 10 Cytosol "Golgi apparatus" "CAB025797: , HPA000980: AB_1078170" "unprognostic (2.20e-1)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (2.64e-1)" "unprognostic (2.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (4.00e-2)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.79e-5)" "unprognostic (5.61e-2)" "unprognostic (1.67e-1)" "unprognostic (8.39e-2)" "prognostic unfavorable (6.98e-4)" APCS "MGC88159, PTX2, SAP" ENSG00000132703 "Amyloid P component, serum" P02743 1 159587826-159588865 "Disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "liver: 3515.6" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 4133.8" "Cancer enriched" "Detected in some" 25 "liver cancer: 826.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "liver cancer: 14.2" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB007817, HPA053294" Supported "Secreted to blood" "No annotated function" NA NA 27700000000 39000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 3 "CAB007817: AB_598185, HPA053294: AB_2682104" "unprognostic (3.19e-3)" "unprognostic (2.30e-2)" APELA "ELA, Ende, tdl" ENSG00000248329 "Apelin receptor early endogenous ligand" P0DMC3 4 164877178-164898965 "Predicted secreted proteins" "Angiogenesis, Differentiation, Gastrulation" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.1;prostate: 4.1" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 28.3;Prostatic glandular cells: 11.1;Proximal tubular cells: 37.3;Syncytiotrophoblasts: 33.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 7.7;testis cancer: 23.1" "Kidney - Ascending Loop of Henle cells" "Secreted in other tissues" Hormone NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "unprognostic (2.97e-2)" "unprognostic (6.97e-2)" "unprognostic (9.83e-4)" "unprognostic (8.92e-3)" "unprognostic (1.43e-3)" "unprognostic (4.50e-2)" "unprognostic (2.21e-1)" "unprognostic (1.71e-1)" "unprognostic (3.38e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-2)" "unprognostic (1.89e-1)" "unprognostic (4.34e-1)" "unprognostic (8.35e-2)" "unprognostic (1.95e-4)" APLN "apelin, XNPEP2" ENSG00000171388 Apelin Q9ULZ1 X 129645259-129654956 "Predicted secreted proteins" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.3;placenta: 52.2" "Cell type enhanced" "Detected in some" "Astrocytes: 7.7;Breast myoepithelial cells: 8.1;Cardiomyocytes: 14.0;Endothelial cells: 20.9;Mesothelial cells: 4.0" "Group enriched" "Detected in all" 6 "glioma: 44.2;renal cancer: 21.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Kidney cancer: 18.8;prostate cancer: 64.5" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" Hormone NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Non-specific - Mixed function" 1 "unprognostic (1.50e-1)" "prognostic unfavorable (2.92e-4)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.50e-2)" "unprognostic (5.94e-2)" "prognostic unfavorable (9.32e-4)" "prognostic unfavorable (6.09e-4)" "unprognostic (4.71e-2)" "unprognostic (2.25e-1)" "unprognostic (3.30e-1)" "unprognostic (9.12e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (1.55e-1)" "unprognostic (1.15e-1)" "unprognostic (2.26e-1)" "unprognostic (8.42e-2)" APOA1 ENSG00000118137 "Apolipoprotein A1" P02647 11 116835751-116837622 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Amyloidosis, Atherosclerosis, Cancer-related genes, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 18779.1" "Group enriched" "Detected in many" 13 "Hepatocytes: 24174.5;Proximal enterocytes: 12804.9" "Cancer enriched" "Detected in many" 48 "liver cancer: 4515.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 14 "Gastric cancer: 176.6;liver cancer: 494.9" "Liver - Hepatocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016778, HPA046715" Supported Approved Vesicles,Cytosol "Secreted to blood" Apolipoprotein NA NA 1450000000000 110000000000 "Cluster 83: Liver - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 10 Vesicles Cytosol "CAB016778: , HPA046715: AB_2679768" "unprognostic (1.88e-3)" "unprognostic (4.53e-2)" "unprognostic (7.46e-2)" "unprognostic (4.00e-3)" "unprognostic (3.70e-2)" "unprognostic (1.41e-1)" "prognostic favorable (5.05e-4)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (9.60e-3)" "unprognostic (1.59e-3)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.67e-8)" "unprognostic (3.46e-3)" "unprognostic (1.15e-1)" "unprognostic (6.24e-2)" "unprognostic (9.54e-2)" APOA2 ENSG00000158874 "Apolipoprotein A2" P02652 1 161222292-161223631 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction, Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1343 "liver: 34742.6" "Cell type enriched" "Detected in some" 78 "Hepatocytes: 51864.9" "Cancer enriched" "Detected in many" 329 "liver cancer: 11230.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "liver cancer: 2178.7" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025885, HPA072575" Supported "Secreted to blood" Apolipoprotein NA NA 115000000000 92000000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 31: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 15 "CAB025885: , HPA072575: " "unprognostic (2.05e-1)" "unprognostic (4.70e-2)" "unprognostic (1.12e-1)" "unprognostic (2.99e-1)" "unprognostic (9.82e-2)" "unprognostic (1.92e-1)" "unprognostic (3.16e-1)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (4.40e-3)" "unprognostic (3.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.60e-1)" "unprognostic (6.09e-2)" APOA4 ENSG00000110244 "Apolipoprotein A4" P06727 11 116820700-116823304 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 3023.3" "Cell type enriched" "Detected in some" 29 "Proximal enterocytes: 7501.7" "Cancer enriched" "Detected in some" 29 "liver cancer: 291.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "liver cancer: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001352, HPA002549, CAB068250, CAB068251, CAB068252" Enhanced Approved Vesicles "Secreted to blood" Apolipoprotein NA NA 61200000000 74000000000 "Cluster 25: Small intestine - Absorption" "Cluster 34: Testis cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 4 Vesicles "CAB068250: AB_2665657, CAB068251: AB_2665659, CAB068252: AB_2665658, HPA001352: AB_1078179, HPA002549: AB_1078177" "unprognostic (8.81e-2)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (7.91e-2)" APOA5 "APOA-V, RAP3" ENSG00000110243 "Apolipoprotein A5" Q6Q788 11 116789367-116792420 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 218 "liver: 567.7" "Cell type enriched" "Detected in some" 59 "Hepatocytes: 1096.0" "Cancer enriched" "Detected in single" 489 "liver cancer: 112.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "liver cancer: 2.7" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Apolipoprotein NA NA 114000000 21000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 12 "unprognostic (1.57e-4)" "unprognostic (4.67e-3)" "unprognostic (5.57e-2)" "unprognostic (2.60e-3)" "unprognostic (2.40e-1)" "unprognostic (2.31e-4)" APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 296.0;liver: 1155.6" "Group enriched" "Detected in some" 7 "Hepatocytes: 2290.4;Proximal enterocytes: 1342.2" "Cancer enriched" "Detected in some" 99 "liver cancer: 295.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "liver cancer: 178.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016070, HPA049793, CAB080297, CAB080298, CAB080299" Supported Supported Vesicles,Cytosol "Secreted to blood" Apolipoprotein NA NA 1490000000000 100000000000 "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 2 "Vesicles, Cytosol" "CAB016070: AB_626690, CAB080297: , CAB080298: , CAB080299: , HPA049793: AB_2680885" "unprognostic (1.63e-2)" "unprognostic (2.71e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-2)" "unprognostic (7.31e-2)" "unprognostic (1.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.43e-2)" "unprognostic (8.89e-3)" "unprognostic (3.01e-1)" "unprognostic (4.59e-3)" "unprognostic (3.60e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (2.99e-1)" "unprognostic (6.23e-2)" APOC1 ENSG00000130208 "Apolipoprotein C1" P02654 19 44914247-44919349 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "liver: 17322.1" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 34314.8" "Cancer enriched" "Detected in all" 21 "liver cancer: 3253.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 5.9" "Lineage enriched" "Detected in single" 14 "dendritic cells: 5.9" "Cancer enhanced" "Detected in all" "Leukemia: 273.6;liver cancer: 289.3" "Liver - Hepatocytes, Lung - Macrophages, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" HPA051518 Supported "Secreted to blood" Apolipoprotein NA NA 20300000000 15000000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 43: Hepatocytes - Metabolism" 23 "HPA051518: AB_2681519" "unprognostic (3.51e-2)" "unprognostic (3.31e-3)" "unprognostic (1.14e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.15e-7)" "unprognostic (9.51e-3)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (1.11e-1)" "unprognostic (2.52e-1)" "unprognostic (7.13e-3)" "unprognostic (3.48e-3)" "unprognostic (1.65e-1)" "unprognostic (2.01e-3)" "unprognostic (1.65e-1)" APOC2 ENSG00000234906 "Apolipoprotein C2" P02655 19 44946035-44949565 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Disease variant, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 130 "liver: 9320.5" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 820.6" "Cancer enriched" "Detected in some" 17 "liver cancer: 49.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 29 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 29 "NK-cells: 3.2" "Cancer enhanced" "Detected in many" "Brain cancer: 55.3;Leukemia: 80.3;liver cancer: 81.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" HPA055877 Supported "Secreted to blood" Apolipoprotein NA NA 43000000000 49000000000 "Cluster 14: Non-specific - Unknown function" "Cluster 31: Liver - Plasma proteins" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 1 "HPA055877: AB_2682953" "unprognostic (4.28e-2)" "unprognostic (7.73e-3)" "unprognostic (1.33e-1)" "unprognostic (3.66e-2)" "unprognostic (8.91e-2)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (1.96e-2)" "unprognostic (2.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.14e-8)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (1.77e-2)" "unprognostic (9.80e-3)" APOC3 "Apo-C3, Apo-CIII, ApoC-3, ApoC-III, APOCIII" ENSG00000110245 "Apolipoprotein C3" P02656 11 116829706-116833072 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 26980.2" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 87587.5" "Cancer enriched" "Detected in many" 643 "liver cancer: 4021.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "liver cancer: 40.4" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA065365, HPA073918" Supported Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Secreted to blood" Apolipoprotein NA NA 106000000000 45000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 3 Nucleoplasm "Nucleoli, Cell Junctions" "HPA065365: AB_2732733, HPA073918: " "prognostic favorable (3.77e-4)" "unprognostic (2.33e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.60e-2)" "unprognostic (5.21e-2)" APOC4 ENSG00000267467 "Apolipoprotein C4" P55056 19 44942237-44945496 "Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 505 "liver: 607.5" "Cell type enriched" "Detected in single" 40 "Hepatocytes: 15.2" "Cancer enriched" "Detected in single" 15 "liver cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062671 Approved "Secreted to blood" Apolipoprotein NA NA 1000000000 980000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 31: Liver - Plasma proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 43: Hepatocytes - Metabolism" 22 "HPA062671: AB_2684828" "unprognostic (1.82e-3)" APOD Apo-D ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 4898.1;choroid plexus: 4317.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 4290.5;Leydig cells: 1994.7;Melanocytes: 1348.5;Peritubular cells: 1105.2;Serous glandular cells: 920.5" "Cancer enriched" "Detected in all" 4 "melanoma: 925.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 4 "breast cancer: 117.8;prostate cancer: 92.2;skin cancer: 170.8" "Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" Apolipoprotein NA NA 98900000000 90000000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 38 "Plasma membrane" "HPA040520: AB_2677020" "prognostic favorable (5.51e-4)" "unprognostic (7.62e-3)" "unprognostic (7.85e-3)" "unprognostic (3.34e-3)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.71e-3)" APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3346.3;brain: 2687.4;liver: 6430.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 8279.7;Hofbauer cells: 5560.9;Leydig cells: 2605.0;Melanocytes: 3267.4;Muller glia cells: 8388.3;Peritubular cells: 4712.6;Proximal tubular cells: 6121.1" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "liver cancer: 501.2;Rhabdoid: 348.5" "Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" Apolipoprotein NA NA 51800000000 29000000000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Macrophages - Innate immune response" 30 Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" APOF ENSG00000175336 "Apolipoprotein F" Q13790 12 56360568-56362857 "Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 346 "liver: 404.0" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 299.3" "Cancer enriched" "Detected in some" 6 "liver cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.0" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Secreted to blood" Apolipoprotein NA NA 18000000000 2200000000 "Cluster 31: Liver - Plasma proteins" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 62: Hepatocytes - Metabolism" "unprognostic (3.55e-2)" "unprognostic (1.13e-1)" "unprognostic (1.48e-2)" "unprognostic (8.99e-3)" "unprognostic (9.84e-2)" "unprognostic (3.29e-2)" "unprognostic (2.08e-3)" "unprognostic (7.84e-2)" "unprognostic (4.22e-1)" "unprognostic (5.69e-2)" "unprognostic (2.68e-3)" "unprognostic (8.55e-2)" "unprognostic (2.42e-2)" "unprognostic (2.77e-1)" "unprognostic (5.57e-2)" "unprognostic (2.87e-1)" "unprognostic (4.43e-2)" APOH "B2G1, BG" ENSG00000091583 "Apolipoprotein H" P02749 17 66212033-66256525 "Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 567 "liver: 17409.3" "Cell type enriched" "Detected in some" 29 "Hepatocytes: 7848.6" "Cancer enriched" "Detected in many" 232 "liver cancer: 2878.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 46 "liver cancer: 154.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Pancreas - Alpha cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA001654, HPA003732, CAB022214" Enhanced Supported "Golgi apparatus" "Secreted to blood" Apolipoprotein NA NA 247000000000 41000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 5 "Golgi apparatus" "CAB022214: , HPA001654: AB_1078181, HPA003732: AB_1078183" "unprognostic (2.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.39e-7)" "unprognostic (1.26e-1)" "unprognostic (5.99e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.26e-2)" "unprognostic (5.76e-2)" APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 174.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 107.3;Glandular and luminal cells: 219.4;Hepatocytes: 97.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 244.0" "Heart muscle - Endothelial cells, Kidney - Endothelial cells" "HPA018885, CAB056156" Supported "Secreted to blood" Apolipoprotein NA NA 1640000000 9200000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Liver - Plasma proteins" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "CAB056156: AB_2665576, HPA018885: AB_1844953" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.98e-3)" "unprognostic (1.67e-1)" "unprognostic (8.28e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (7.43e-6)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-3)" "prognostic favorable (2.01e-5)" APOL3 "APOLIII, CG12-1" ENSG00000128284 "Apolipoprotein L3" O95236 22 36140329-36166177 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 54.9;Endothelial cells: 64.6;Kupffer cells: 35.3;Lymphatic endothelial cells: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Testis - Endothelial cells" "Intracellular and membrane" Apolipoprotein NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "prognostic favorable (6.82e-4)" "unprognostic (5.93e-3)" "unprognostic (6.79e-2)" "unprognostic (2.70e-2)" "unprognostic (2.22e-1)" "unprognostic (7.05e-2)" "unprognostic (6.30e-2)" "unprognostic (2.67e-1)" "unprognostic (8.94e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (7.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" APOL4 APOLIV ENSG00000100336 "Apolipoprotein L4" Q9BPW4 22 36189124-36204840 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 15.6;Glandular and luminal cells: 53.1;Prostatic glandular cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leukemia: 15.5;lymphoma: 4.5" "HPA049797, HPA055435" Uncertain Supported Vesicles "Secreted to blood" Apolipoprotein NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Glandular & Luminal cells - Unknown function" Vesicles "HPA049797: AB_2680887, HPA055435: AB_2682816" "unprognostic (2.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.51e-1)" "unprognostic (5.31e-1)" "unprognostic (3.39e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "prognostic favorable (3.45e-4)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (2.00e-5)" "unprognostic (4.26e-2)" "unprognostic (3.69e-1)" "unprognostic (4.18e-2)" "prognostic favorable (2.40e-6)" APOM "Apo-M, G3a, NG20" ENSG00000204444 "Apolipoprotein M" O95445 6 31652416-31658210 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 381.2" "Group enriched" "Detected in many" 7 "Hepatocytes: 703.0;Proximal tubular cells: 402.9" "Cancer enriched" "Detected in all" 13 "liver cancer: 185.9" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "liver cancer: 6.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034086, HPA051006" Approved Approved "Golgi apparatus" "Secreted to blood" Apolipoprotein NA NA 7400000000 8200000000 "Cluster 32: Basophils - Transcription" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Golgi apparatus" "CAB034086: AB_1119033, HPA051006: AB_2681307" "unprognostic (2.76e-3)" "unprognostic (1.69e-2)" "unprognostic (8.66e-2)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (5.28e-2)" "unprognostic (3.78e-1)" "unprognostic (1.97e-2)" "unprognostic (1.80e-1)" "unprognostic (6.04e-3)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (7.28e-2)" "unprognostic (5.71e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-1)" "unprognostic (3.20e-2)" APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 105.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 110.6;Oocytes: 124.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Approved Mitochondria,Cytosol "Secreted to blood" Apolipoprotein NA NA 2210000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA003187: AB_1079375" "unprognostic (2.53e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.86e-2)" "unprognostic (6.38e-3)" "unprognostic (3.45e-1)" "unprognostic (2.42e-1)" "unprognostic (6.18e-2)" "unprognostic (2.95e-1)" "unprognostic (6.45e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "prognostic favorable (2.56e-6)" "unprognostic (2.53e-2)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (5.88e-3)" APOOL "AAIR8193, CXorf33, FAM121A, Mic27, MICOS27, UNQ8193" ENSG00000155008 "Apolipoprotein O like" Q6UXV4 X 85003877-85093315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000612, HPA076210" Approved Enhanced Mitochondria "Intracellular and membrane" Apolipoprotein NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 32: Smooth muscle cells - Muscle contraction" Mitochondria "HPA000612: AB_1078594, HPA076210: " "prognostic unfavorable (2.68e-5)" "unprognostic (2.72e-2)" "unprognostic (6.16e-2)" "unprognostic (5.71e-3)" "unprognostic (4.27e-3)" "unprognostic (1.47e-1)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (8.35e-2)" "unprognostic (1.10e-1)" "unprognostic (2.77e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.35e-12)" "unprognostic (2.67e-2)" "unprognostic (5.65e-2)" "unprognostic (7.11e-2)" "unprognostic (7.51e-2)" APP "AD1, alpha-sAPP" ENSG00000142192 "Amyloid beta precursor protein" P05067 21 25880535-26171128 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Apoptosis, Cell adhesion, Endocytosis, Notch signaling pathway" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Alzheimer disease, Amyloidosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 810.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 36.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 36.4" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000157, HPA001462" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Cell adhesion" NA NA 26000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 312 "Golgi apparatus" Vesicles "CAB000157: AB_323833, HPA001462: AB_1078185" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (1.92e-1)" "unprognostic (3.69e-3)" "unprognostic (2.54e-1)" "unprognostic (8.22e-2)" "unprognostic (1.28e-1)" "unprognostic (9.45e-2)" "unprognostic (4.28e-2)" "unprognostic (5.35e-2)" "prognostic favorable (2.79e-6)" "unprognostic (3.77e-2)" "unprognostic (2.46e-1)" "unprognostic (5.23e-2)" "unprognostic (2.08e-3)" ARHGAP6 rhoGAPX-1 ENSG00000047648 "Rho GTPase activating protein 6" O43182 X 11117651-11665920 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 141.4;Mesothelial cells: 61.5;Microglial cells: 121.7;Oligodendrocyte precursor cells: 56.6;Prostatic glandular cells: 177.5" "Cancer enhanced" "Detected in many" "prostate cancer: 12.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 22.1" "Liver - Hepatic stellate cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001798, HPA036779, HPA064390" Enhanced Supported Cytosol "Intracellular and membrane" Other NA NA 350000 "Cluster 62: Connective tissue - ECM organization" "Cluster 21: Non-specific - Metabolism" "Cluster 60: Prostate cancer - Unknown function" "Cluster 57: Platelets - Hemostasis" Cytosol "HPA001798: , HPA036779: AB_10672229, HPA064390: AB_2685253" "unprognostic (2.36e-1)" "unprognostic (1.68e-2)" "unprognostic (3.49e-2)" "unprognostic (7.31e-2)" "unprognostic (6.34e-2)" "unprognostic (1.69e-2)" "unprognostic (4.70e-2)" "unprognostic (2.79e-1)" "unprognostic (1.70e-1)" "unprognostic (7.46e-4)" "unprognostic (1.53e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.55e-8)" "unprognostic (1.60e-2)" "unprognostic (5.96e-2)" "unprognostic (1.28e-2)" "unprognostic (7.99e-4)" ARMC5 FLJ13063 ENSG00000140691 "Armadillo repeat containing 5" Q96C12 16 31458080-31467166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041524, HPA063706" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" "Intracellular and membrane" "No annotated function" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 56: Non-specific - Unknown function" "Cluster 49: Hindbrain - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 80: Non-specific - Transcription" 8 "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA041524: AB_10796676, HPA063706: AB_2685098" "unprognostic (1.37e-1)" "unprognostic (1.68e-3)" "unprognostic (8.22e-3)" "unprognostic (9.96e-2)" "unprognostic (2.59e-1)" "unprognostic (2.94e-3)" "unprognostic (4.09e-2)" "unprognostic (6.14e-3)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" "prognostic favorable (1.97e-6)" "unprognostic (4.70e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-2)" "unprognostic (2.34e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" ARSA ASA ENSG00000100299 "Arylsulfatase A" P15289 22 50622754-50628173 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 125.6;Plasma cells: 119.7;Proximal enterocytes: 95.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005554, CAB025183" Enhanced Uncertain "Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA 5600000 "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 66: Non-specific - Mitochondria" "Cluster 77: Plasma cells - Protein processing" 11 "Golgi apparatus" Cytosol "CAB025183: , HPA005554: AB_1078220" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (4.07e-2)" "prognostic favorable (2.96e-5)" "unprognostic (4.66e-2)" "unprognostic (4.40e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-2)" "unprognostic (2.16e-1)" "unprognostic (4.47e-2)" "unprognostic (2.76e-1)" "unprognostic (9.90e-2)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (7.73e-3)" ARSB ASB ENSG00000113273 "Arylsulfatase B" P15848 5 78777209-78986087 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 38.7;Excitatory neurons: 36.1;Inhibitory neurons: 40.7;Microglial cells: 38.5;Oligodendrocyte precursor cells: 67.0;Oligodendrocytes: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 25.5" "Group enriched" "Detected in many" 7 "dendritic cells: 7.8;granulocytes: 25.5;monocytes: 8.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037770, HPA037771" Approved Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Liver - Plasma proteins" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Golgi apparatus" "HPA037770: AB_10671719, HPA037771: AB_10671720" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "unprognostic (1.97e-2)" "unprognostic (1.09e-2)" "unprognostic (7.34e-2)" "unprognostic (2.65e-1)" "unprognostic (8.69e-3)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (7.20e-2)" "unprognostic (1.74e-1)" "unprognostic (3.59e-2)" "unprognostic (2.48e-2)" "unprognostic (9.57e-3)" "unprognostic (9.88e-2)" "unprognostic (6.54e-3)" "prognostic unfavorable (3.42e-4)" ARSF ASF ENSG00000062096 "Arylsulfatase F" P54793 X 3041471-3112727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.7;kidney: 7.3;skin 1: 5.5" "Cell type enhanced" "Detected in some" "Astrocytes: 9.0;Inhibitory neurons: 4.4;Oligodendrocyte precursor cells: 2.4;Proximal tubular cells: 7.1;Serous glandular cells: 4.4" "Cancer enhanced" "Detected in some" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" HPA000549 Approved Vesicles,Cytosol "Secreted in other tissues" Enzyme NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Vesicles, Cytosol" "HPA000549: AB_1845055" "unprognostic (2.19e-2)" "unprognostic (8.88e-2)" "unprognostic (2.87e-1)" "unprognostic (5.41e-3)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (9.72e-2)" "unprognostic (4.70e-1)" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (3.05e-2)" "unprognostic (3.59e-1)" "unprognostic (1.23e-1)" "unprognostic (9.76e-2)" "unprognostic (1.48e-1)" ARSG KIAA1001 ENSG00000141337 "Arylsulfatase G" Q96EG1 17 68259182-68422731 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 29.5" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023245, HPA023285" Enhanced "Intracellular and membrane" Enzyme NA NA 4400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 55: Non-specific - Transcription" "HPA023245: AB_1845056, HPA023285: AB_1845057" "unprognostic (3.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" "unprognostic (1.61e-1)" "unprognostic (9.02e-2)" "unprognostic (3.67e-3)" "unprognostic (4.11e-1)" "unprognostic (1.14e-3)" "unprognostic (5.18e-2)" "unprognostic (5.47e-2)" "unprognostic (6.11e-7)" "unprognostic (4.24e-3)" "prognostic favorable (7.04e-4)" "unprognostic (1.87e-2)" "unprognostic (3.68e-2)" "unprognostic (3.18e-2)" "unprognostic (1.49e-1)" ARSI "FLJ16069, SPG66" ENSG00000183876 "Arylsulfatase family member I" Q5FYB1 5 150296343-150339307 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 15.4;Fibroblasts: 10.4;granulocytes: 11.5;Melanocytes: 24.0;Mesothelial cells: 7.3;Pancreatic endocrine cells: 17.0;Suprabasal keratinocytes: 14.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 10.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 33.8" "Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "HPA038386, HPA038398, HPA077833" Uncertain Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" Enzyme NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Connective tissue cells - ECM organization" 1 "Golgi apparatus" Vesicles "HPA038386: AB_10669781, HPA038398: AB_2675995, HPA077833: " "unprognostic (6.08e-2)" "unprognostic (1.70e-2)" "unprognostic (9.41e-3)" "unprognostic (4.77e-3)" "unprognostic (1.54e-3)" "unprognostic (2.83e-3)" "unprognostic (2.76e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.06e-1)" "unprognostic (5.81e-3)" "unprognostic (4.85e-2)" "unprognostic (1.26e-1)" "unprognostic (3.39e-7)" "unprognostic (7.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.19e-4)" ARSJ FLJ23548 ENSG00000180801 "Arylsulfatase family member J" Q5FYB0 4 113900284-113979727 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 49.7;Astrocytes: 41.8;Collecting duct cells: 23.3;Excitatory neurons: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA036481, HPA036482" Uncertain Enhanced "Actin filaments" "Secreted in other tissues" Enzyme NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" "Actin filaments" "HPA036481: AB_2675146, HPA036482: AB_10672356" "unprognostic (1.98e-1)" "unprognostic (1.55e-2)" "unprognostic (4.23e-1)" "unprognostic (5.31e-1)" "unprognostic (6.23e-2)" "prognostic unfavorable (6.08e-4)" "unprognostic (2.54e-2)" "unprognostic (2.49e-2)" "unprognostic (1.60e-1)" "unprognostic (1.04e-1)" "unprognostic (5.31e-2)" "unprognostic (2.20e-1)" "prognostic favorable (2.97e-6)" "unprognostic (2.26e-1)" "unprognostic (8.37e-2)" "unprognostic (1.30e-1)" "unprognostic (2.07e-2)" ARSK "DKFZp313G1735, TSULF" ENSG00000164291 "Arylsulfatase family member K" Q6UWY0 5 95555101-95605102 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 18.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042384 Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 31: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA042384: AB_10795703" "unprognostic (9.50e-2)" "unprognostic (1.37e-1)" "unprognostic (2.03e-3)" "unprognostic (2.39e-1)" "unprognostic (3.33e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (2.59e-4)" "unprognostic (3.39e-1)" "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (7.61e-2)" "unprognostic (2.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.91e-2)" "unprognostic (2.32e-1)" "unprognostic (8.20e-2)" "unprognostic (1.06e-2)" ART3 ARTC3 ENSG00000156219 "ADP-ribosyltransferase 3 (inactive)" Q13508 4 76011184-76114048 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 65.2;skeletal muscle: 191.5;testis: 89.6;tongue: 72.9" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 75.1;Skeletal myocytes: 247.9;Spermatocytes: 253.1" "Cancer enhanced" "Detected in some" "breast cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "breast cancer: 6.9;skin cancer: 17.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA011268 Enhanced "Intracellular and membrane" Enzyme NA NA 48000000 "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 31: Spermatocytes - Spermatogenesis" "HPA011268: AB_1845059" "unprognostic (2.45e-1)" "unprognostic (2.84e-2)" "unprognostic (3.12e-2)" "unprognostic (2.77e-3)" "unprognostic (4.53e-2)" "unprognostic (1.34e-1)" "unprognostic (3.34e-1)" "unprognostic (9.85e-4)" "unprognostic (2.35e-1)" "unprognostic (5.10e-2)" "unprognostic (1.64e-2)" "unprognostic (2.95e-1)" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.48e-1)" "unprognostic (2.58e-2)" "unprognostic (6.61e-3)" ART4 "ARTC4, CD297, DO, DOK1" ENSG00000111339 "ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)" Q93070 12 14825569-14843526 "Blood group antigen proteins, CD markers, Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood group antigen, Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 51.6;lymphoid tissue: 18.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 11.4;Endothelial cells: 15.2;Erythroid cells: 36.2;Hepatocytes: 27.2;Lymphatic endothelial cells: 52.6;Rod photoreceptor cells: 12.6" "Group enriched" "Detected in some" 5 "liver cancer: 3.8;pancreatic cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 11.7" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Low region specificity" "Detected in all" HPA075664 Approved "Rods & Rings" "Secreted to blood" Enzyme NA NA 17000000 "Cluster 83: Liver - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Rods & Rings" "HPA075664: " "unprognostic (2.50e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-1)" "unprognostic (1.18e-2)" "unprognostic (1.55e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-1)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.62e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-3)" "unprognostic (1.05e-1)" "unprognostic (1.71e-1)" ART5 ARTC5 ENSG00000167311 "ADP-ribosyltransferase 5" Q96L15 11 3638512-3642316 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 11.4;skeletal muscle: 13.0;testis: 28.6" "Cell type enhanced" "Detected in some" "Early spermatids: 19.8;Late spermatids: 16.6;Oocytes: 14.0;Ovarian stromal cells: 9.7;Skeletal myocytes: 15.6;Spermatocytes: 55.1" "Cancer enriched" "Detected in some" 4 "testis cancer: 4.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 12.7" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041637, HPA044099" Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA041637: AB_2677589, HPA044099: AB_2678808" "unprognostic (6.32e-2)" "unprognostic (3.26e-5)" "unprognostic (4.09e-3)" "unprognostic (2.06e-4)" "unprognostic (1.53e-2)" "unprognostic (1.47e-2)" "unprognostic (2.22e-2)" "unprognostic (1.21e-2)" "unprognostic (5.65e-2)" "unprognostic (2.59e-2)" "unprognostic (1.17e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.85e-4)" "unprognostic (3.10e-3)" "unprognostic (3.46e-2)" "unprognostic (1.96e-1)" "unprognostic (3.18e-1)" ARTN "ENOVIN, EVN, NBN" ENSG00000117407 Artemin Q5T4W7 1 43933320-43937240 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Club cells: 4.3;Early spermatids: 10.1;Granulosa cells: 8.3;Ionocytes: 4.4;Rod photoreceptor cells: 5.3;Smooth muscle cells: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 47.6;head and neck cancer: 57.7" "Region enriched" "Detected in single" 9 "olfactory bulb: 3.3" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.5" "Secreted in other tissues" "Growth factor" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (3.07e-3)" "unprognostic (1.18e-1)" "unprognostic (3.08e-1)" "prognostic favorable (8.18e-4)" "unprognostic (2.34e-1)" "unprognostic (1.70e-1)" "unprognostic (9.59e-6)" "unprognostic (2.35e-2)" "unprognostic (3.04e-2)" "unprognostic (1.48e-3)" "unprognostic (1.53e-1)" ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 553.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 870.4;Hofbauer cells: 938.2;monocytes: 1587.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 270.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" Enzyme NA NA 400000 "Cluster 40: Monocytes - Innate immune response" "Cluster 30: Heart muscle - Heart development" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 29: Monocytes - Innate immune response" 1 "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" ASAH2 ENSG00000188611 "N-acylsphingosine amidohydrolase 2" Q9NR71 10 50182778-50279720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 76.1" "Group enriched" "Detected in some" 4 "Early spermatids: 2.9;Late spermatids: 11.3;Muller glia cells: 6.4;Proximal enterocytes: 11.5" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "cerebellum: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061171 Supported Approved "Focal adhesion sites" "Intracellular and membrane" Enzyme NA NA 2200000 "Cluster 25: Small intestine - Absorption" "Cluster 45: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 11: Late spermatids - Unknown function" "Focal adhesion sites" "HPA061171: AB_2684442" "unprognostic (3.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.66e-1)" "unprognostic (3.84e-2)" "unprognostic (3.66e-1)" "unprognostic (4.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-2)" "unprognostic (4.33e-2)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.86e-2)" "unprognostic (5.64e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" ASCL1 "ASH1, bHLHa46, HASH1" ENSG00000139352 "Achaete-scute family bHLH transcription factor 1" P50553 12 102957674-102960513 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.5;liver: 10.7;pituitary gland: 29.3" "Group enriched" "Detected in some" 4 "Astrocytes: 16.1;Enteroendocrine cells: 10.7;Oligodendrocyte precursor cells: 40.1;Pancreatic endocrine cells: 11.9" "Group enriched" "Detected in many" 6 "glioma: 21.4;lung cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "lung cancer: 99.1;Neuroblastoma: 67.5;prostate cancer: 57.5" "Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029217, HPA076307" Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" "Developmental protein" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Oligodendrocyte precursor - Unknown function" 6 Nucleoplasm Cytosol "HPA029217: AB_10669595, HPA076307: " "unprognostic (7.92e-2)" "unprognostic (4.37e-3)" "unprognostic (4.55e-2)" "unprognostic (5.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.22e-2)" "unprognostic (1.56e-1)" "unprognostic (2.09e-1)" "unprognostic (4.84e-2)" "unprognostic (1.31e-2)" "unprognostic (1.31e-1)" "unprognostic (7.10e-6)" "unprognostic (3.40e-1)" "unprognostic (2.17e-1)" "unprognostic (3.76e-1)" "unprognostic (5.52e-2)" ASGR1 CLEC4H1 ENSG00000141505 "Asialoglycoprotein receptor 1" P07306 17 7173431-7179564 "Predicted intracellular proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1065.6" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 976.9" "Cancer enriched" "Detected in many" 90 "liver cancer: 131.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 115.4;intermediate monocyte: 55.6;myeloid DC: 41.2" "Group enriched" "Detected in many" 8 "dendritic cells: 41.2;monocytes: 115.4" "Cancer enriched" "Detected in many" 11 "liver cancer: 80.4" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 9 "cerebellum: 44.1" "Not detected" "Not detected" "HPA011954, HPA012852" Enhanced Supported "Vesicles,Cell Junctions" "Secreted to blood" Receptor NA NA 10000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 31: Liver - Plasma proteins" "Cluster 2: Neurons - Nucleosome" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 27 Vesicles "Cell Junctions" "HPA011954: AB_1845079, HPA012852: AB_1845080" "unprognostic (3.56e-3)" "unprognostic (3.57e-1)" "unprognostic (8.76e-2)" "unprognostic (4.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (5.37e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (8.55e-5)" "unprognostic (1.55e-1)" "unprognostic (8.33e-11)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-3)" "unprognostic (4.46e-3)" ASIP "AGTIL, ASP" ENSG00000101440 "Agouti signaling protein" P42127 20 34194569-34269344 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 11.9;heart muscle: 27.1;ovary: 40.4" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 26.2;dendritic cells: 81.0;Ovarian stromal cells: 103.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 340 "plasmacytoid DC: 125.9" "Lineage enriched" "Detected in single" 340 "dendritic cells: 125.9" "Cancer enhanced" "Detected in many" "Bone cancer: 4.5" "Heart muscle - Cardiomyocytes, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048636 Uncertain Supported Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 62: Connective tissue - ECM organization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 6: Ovarian stromal cells - Transcription" Vesicles "HPA048636: AB_2680471" "unprognostic (4.81e-2)" "unprognostic (7.46e-2)" "unprognostic (1.97e-3)" "unprognostic (3.26e-2)" "unprognostic (2.24e-1)" "unprognostic (3.07e-2)" "unprognostic (5.13e-2)" "unprognostic (4.57e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (5.53e-6)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" ASPN "FLJ20129, PLAP-1, SLRR1C" ENSG00000106819 Asporin Q9BXN1 9 92456205-92482506 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 92.0;smooth muscle: 106.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 40.4;Fibroblasts: 71.3;Microglial cells: 23.3;Ovarian stromal cells: 17.3;Sertoli cells: 21.8;Smooth muscle cells: 62.8" "Cancer enhanced" "Detected in all" "breast cancer: 51.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.8" "Cancer enhanced" "Detected in single" "Brain cancer: 1.0" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007894, HPA008435, HPA024230" Approved Uncertain Nucleoplasm,Cytosol "Secreted to extracellular matrix" Other NA NA 2100000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA007894: , HPA008435: AB_1845112, HPA024230: AB_1845113" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (8.13e-3)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.01e-2)" "unprognostic (9.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-3)" "unprognostic (6.38e-2)" "unprognostic (3.70e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (1.64e-7)" "unprognostic (1.42e-3)" "unprognostic (3.04e-2)" "unprognostic (6.27e-3)" "unprognostic (2.48e-2)" ASTL "ovastacin, SAS1B" ENSG00000188886 "Astacin like metalloendopeptidase" Q6HA08 2 96122818-96138502 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Fertilization "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.8" "Cell type enhanced" "Detected in some" "Macrophages: 1.1;T-cells: 1.8" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Region enriched" "Detected in some" 5 "cerebral cortex: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA015620 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 7: T-cells - T-cell receptor" 1 "HPA015620: AB_1845121" "unprognostic (3.21e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-2)" "unprognostic (3.45e-4)" "unprognostic (1.00e-2)" "unprognostic (3.03e-2)" "unprognostic (3.53e-2)" "unprognostic (5.12e-2)" "unprognostic (3.62e-1)" "unprognostic (3.40e-1)" "unprognostic (1.95e-1)" "unprognostic (2.61e-5)" "unprognostic (3.41e-3)" "unprognostic (1.08e-1)" "unprognostic (1.67e-1)" "unprognostic (9.93e-3)" ATAD5 "C17orf41, ELG1, FLJ12735, FRAG1" ENSG00000176208 "ATPase family AAA domain containing 5" Q96QE3 17 30831966-30895869 "Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 54.5;Spermatocytes: 72.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA066823 Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol" "Intracellular and membrane" Other Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 52: Non-specific - Cell proliferation" Nucleoplasm "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA066823: " "unprognostic (3.12e-1)" "unprognostic (7.36e-2)" "unprognostic (1.12e-2)" "unprognostic (1.36e-3)" "unprognostic (3.33e-1)" "unprognostic (1.05e-2)" "unprognostic (1.28e-4)" "unprognostic (1.77e-1)" "unprognostic (1.79e-3)" "unprognostic (7.24e-2)" "unprognostic (2.78e-1)" "unprognostic (3.19e-3)" "unprognostic (6.30e-10)" "unprognostic (3.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.42e-1)" "unprognostic (1.38e-1)" ATAT1 "C6orf134, Em:AB023049.7, FLJ13158, MEC17" ENSG00000137343 "Alpha tubulin acetyltransferase 1" Q5SQI0 6 30626842-30646823 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.1" "Cell type enhanced" "Detected in all" "Early spermatids: 95.6;Late spermatids: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046816, HPA050999" Approved Supported "Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 34: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 10: Muller glia cells - Visual perception" Cytosol "Golgi apparatus" "HPA046816: AB_2679822, HPA050999: AB_2681303" "unprognostic (3.98e-1)" "unprognostic (3.18e-1)" "unprognostic (4.30e-2)" "unprognostic (2.67e-2)" "unprognostic (8.86e-2)" "unprognostic (8.18e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (1.49e-2)" "unprognostic (5.39e-2)" "unprognostic (2.37e-2)" "unprognostic (1.29e-3)" "unprognostic (1.25e-2)" "prognostic unfavorable (7.78e-5)" "unprognostic (2.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.02e-1)" "prognostic favorable (1.35e-4)" ATG2A "BLTP4A, KIAA0404" ENSG00000110046 "Autophagy related 2A" Q2TAZ0 11 64894546-64917211 "Predicted intracellular proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 67.6;Syncytiotrophoblasts: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 17.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 17.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038715 Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" Transport NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 56: Non-specific - Unknown function" "Cluster 12: Non-specific - Vasculature" "Cluster 24: Non-specific - Unknown function" "Cluster 74: Neutrophils - Degranulation" 7 Vesicles Nucleoplasm "HPA038715: AB_10673474" "unprognostic (3.05e-2)" "unprognostic (2.33e-1)" "unprognostic (7.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.42e-1)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.79e-5)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (3.37e-1)" "unprognostic (1.15e-1)" ATG5 "APG5, APG5L, ASP, hAPG5" ENSG00000057663 "Autophagy related 5" Q9H1Y0 6 106045423-106325791 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Host-virus interaction, Immunity" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034432, CAB037309, HPA042973" Approved Approved Centrosome "Intracellular and membrane" Immunity NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Plasma cells - Humoral immune response" 18 Centrosome "CAB034432: AB_2243288, CAB037309: AB_796188, HPA042973: AB_2678246" "unprognostic (1.21e-3)" "unprognostic (6.53e-3)" "unprognostic (2.68e-3)" "unprognostic (4.14e-1)" "unprognostic (1.13e-1)" "unprognostic (6.35e-3)" "prognostic unfavorable (8.84e-4)" "unprognostic (1.60e-1)" "unprognostic (1.34e-1)" "unprognostic (3.34e-1)" "unprognostic (9.60e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.86e-1)" "unprognostic (2.37e-1)" "unprognostic (2.51e-1)" "unprognostic (6.42e-2)" ATMIN "ASCIZ, KIAA0431, ZNF822" ENSG00000166454 "ATM interactor" O43313 16 81035842-81047350 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 154.4;Late spermatids: 296.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054967, HPA066900" Approved Supported "Nuclear bodies" "Intracellular and membrane" Transcription NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 11: Late spermatids - Unknown function" 1 "Nuclear bodies" "HPA054967: AB_2682654, HPA066900: AB_2685744" "unprognostic (9.92e-2)" "unprognostic (3.31e-1)" "unprognostic (4.47e-2)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (9.32e-2)" "unprognostic (4.69e-2)" "unprognostic (1.31e-1)" "unprognostic (1.46e-1)" "unprognostic (6.51e-3)" "unprognostic (1.48e-1)" "unprognostic (4.26e-2)" "prognostic favorable (6.80e-4)" "unprognostic (1.08e-1)" "unprognostic (5.94e-2)" "unprognostic (1.24e-1)" "unprognostic (4.60e-1)" ATP5PB ATP5F1 ENSG00000116459 "ATP synthase peripheral stalk-membrane subunit b" P24539 1 111448864-111462773 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 131.3;tongue: 126.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 768.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046067, HPA057347" Enhanced Supported Mitochondria "Intracellular and membrane" Transport NA NA 170000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mitochondria" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 12 Mitochondria "HPA046067: AB_10960850, HPA057347: AB_2683416" "unprognostic (4.18e-1)" "unprognostic (6.83e-2)" "unprognostic (1.10e-3)" "unprognostic (1.73e-2)" "unprognostic (3.56e-2)" "unprognostic (8.18e-2)" "unprognostic (8.52e-3)" "unprognostic (8.82e-2)" "unprognostic (3.67e-2)" "unprognostic (7.18e-3)" "unprognostic (3.29e-1)" "unprognostic (2.92e-1)" "prognostic favorable (3.26e-9)" "prognostic favorable (8.07e-4)" "unprognostic (1.60e-1)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" ATPAF1 "ATP11, Atp11p, FLJ22351" ENSG00000123472 "ATP synthase mitochondrial F1 complex assembly factor 1" Q5TC12 1 46632737-46673867 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 304.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 290.0;Distal tubular cells: 172.1;Early spermatids: 218.6;Late spermatids: 407.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028382, HPA044950" Approved Approved Mitochondria "Intracellular and membrane" "No annotated function" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA028382: AB_2672574, HPA044950: AB_2679151" "unprognostic (1.34e-1)" "unprognostic (2.97e-3)" "unprognostic (1.18e-2)" "unprognostic (5.96e-2)" "unprognostic (1.20e-1)" "unprognostic (5.97e-2)" "unprognostic (3.53e-1)" "unprognostic (1.72e-2)" "unprognostic (1.70e-2)" "unprognostic (1.19e-2)" "unprognostic (5.15e-2)" "unprognostic (1.05e-1)" "prognostic favorable (5.33e-7)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.44e-1)" "unprognostic (2.62e-1)" ATRN "DPPT-L, MGCA" ENSG00000088812 Attractin O75882 20 3471018-3651118 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 98.2;Inhibitory neurons: 96.8;Oligodendrocyte precursor cells: 84.0;Oligodendrocytes: 79.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008853 Approved Approved Cytosol "Secreted to blood" Receptor NA NA 27000000000 "Cluster 22: Eosinophils - Transcription" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 62: Hepatocytes - Metabolism" Cytosol "HPA008853: AB_1078248" "unprognostic (6.42e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-1)" "unprognostic (5.27e-2)" "unprognostic (1.65e-1)" "unprognostic (3.99e-2)" "unprognostic (4.28e-1)" "unprognostic (3.40e-2)" "unprognostic (4.61e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.19e-6)" "unprognostic (3.71e-2)" "unprognostic (9.49e-2)" "unprognostic (2.77e-1)" "unprognostic (3.91e-2)" AUH ENSG00000148090 "AU RNA binding methylglutaconyl-CoA hydratase" Q13825 9 91213815-91361918 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" "Lyase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 131.5;Oligodendrocytes: 128.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004171 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 8: Neurons - Neuronal signaling" "HPA004171: AB_1845215" "unprognostic (4.10e-2)" "unprognostic (8.95e-2)" "unprognostic (5.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (3.24e-2)" "unprognostic (3.05e-2)" "unprognostic (3.57e-1)" "unprognostic (1.11e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.23e-3)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" AVP "ADH, ARVP" ENSG00000101200 "Arginine vasopressin" P01185 20 3082556-3084724 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Host-virus interaction" "Hormone, Vasoactive, Vasoconstrictor" "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 748 "brain: 4430.7" "Group enriched" "Detected in some" 6 "dendritic cells: 13.8;Late spermatids: 25.6;Proximal tubular cells: 44.6" "Not detected" "Not detected" "Region enriched" "Detected in many" 76 "hypothalamus: 15977.0" "Immune cell enriched" "Detected in single" 6 "eosinophil: 2.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.8" "Cancer enriched" "Detected in single" 108 "Leukemia: 13.5" "Kidney - Proximal tubular cells, Testis - Late spermatids" "Region enriched" "Detected in many" 10 "hypothalamus: 232.8" "Group enriched" "Detected in many" 489 "basal ganglia: 2270.2;hypothalamus: 2082.9" "CAB025318, HPA071892" Enhanced Supported "Secreted to blood" Hormone NA NA 19300 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 "CAB025318: , HPA071892: AB_2732190" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2718.3;salivary gland: 3732.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1494.4;Hepatocytes: 4213.4;Mucus glandular cells: 2188.5;Prostatic glandular cells: 4198.4;Serous glandular cells: 4020.8" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 226.3;prostate cancer: 78.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" "No annotated function" NA NA 55200000000 74000000000 "Cluster 68: Non-specific - Protein processing" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 2 Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 49 "bone marrow: 1577.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.5;Breast myoepithelial cells: 5.3;Ciliated cells: 8.9;Erythroid cells: 6.4;Hofbauer cells: 4.8;Kupffer cells: 3.9;Spermatogonia: 7.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.3" "Cancer enriched" "Detected in single" 40 "Leukemia: 39.1" "Liver - Erythroid cells, Lung - Neutrophil_1" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" Defense NA NA 320000 "Cluster 4: Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" Vesicles "HPA055851: AB_2682943, HPA075964: " "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (4.44e-2)" "unprognostic (8.85e-3)" "unprognostic (1.62e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-3)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-6)" "unprognostic (1.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" "unprognostic (3.04e-2)" B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711358-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 20023.7;Proximal enterocytes: 18472.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA NA 1790000000 2100000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 11 "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" B3GALNT2 MGC39558 ENSG00000162885 "Beta-1,3-N-acetylgalactosaminyltransferase 2" Q8NCR0 1 235447190-235504452 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 127.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007846, HPA050662" Approved Uncertain "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 45: Non-specific - Nuclear processes" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "Golgi apparatus" "HPA007846: , HPA050662: AB_2681209" "unprognostic (5.50e-2)" "unprognostic (3.16e-3)" "unprognostic (6.60e-2)" "unprognostic (1.63e-1)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (7.59e-3)" "unprognostic (1.96e-2)" "unprognostic (3.39e-2)" "unprognostic (3.38e-1)" "unprognostic (7.19e-3)" "unprognostic (2.89e-1)" "unprognostic (1.99e-1)" "unprognostic (5.52e-2)" "unprognostic (3.40e-1)" "unprognostic (3.53e-3)" "unprognostic (8.34e-3)" B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "intestine: 44.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 144.4;Enteroendocrine cells: 35.4;Intestinal goblet cells: 62.6;Paneth cells: 62.1;Proximal enterocytes: 82.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 11.1;pancreatic cancer: 14.9" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 11.4" "HPA054092, HPA054684" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "HPA054092: AB_2682375, HPA054684: AB_2682573" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "prognostic favorable (6.36e-4)" "unprognostic (9.23e-2)" "unprognostic (4.62e-2)" "unprognostic (4.06e-2)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.86e-3)" "unprognostic (1.67e-1)" "unprognostic (6.09e-4)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" B3GAT1 "CD57, GlcAT-P, HNK-1, LEU7, NK-1" ENSG00000109956 "Beta-1,3-glucuronyltransferase 1" Q9P2W7 11 134378504-134412242 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 193.4" "Cell type enhanced" "Detected in some" "Astrocytes: 26.0;Bipolar cells: 30.4;Excitatory neurons: 35.9;Horizontal cells: 40.9;Inhibitory neurons: 29.0;Muller glia cells: 95.7;Oligodendrocyte precursor cells: 31.1;Oligodendrocytes: 72.4" "Group enriched" "Detected in some" 11 "glioma: 10.8;prostate cancer: 3.5;thyroid cancer: 4.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Lineage enriched" "Detected in single" 12 "T-cells: 1.1" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.1" "Heart muscle - T-cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002500, CAB010893, HPA069468, HPA074314" Enhanced Enhanced Vesicles "Secreted in brain" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 10: Muller glia cells - Visual perception" 1 Vesicles "CAB002500: AB_563601, CAB010893: AB_1078474, HPA069468: AB_2686138, HPA074314: " "unprognostic (6.72e-2)" "unprognostic (3.97e-4)" "unprognostic (2.13e-2)" "unprognostic (1.40e-3)" "unprognostic (5.52e-2)" "unprognostic (2.60e-3)" "unprognostic (6.30e-2)" "unprognostic (1.96e-2)" "unprognostic (8.74e-2)" "unprognostic (2.72e-1)" "unprognostic (1.57e-3)" "unprognostic (1.58e-1)" "unprognostic (9.34e-3)" "unprognostic (3.87e-3)" "unprognostic (2.42e-1)" "unprognostic (4.07e-2)" "unprognostic (2.26e-2)" B3GAT3 GlcAT-I ENSG00000149541 "Beta-1,3-glucuronyltransferase 3" O94766 11 62615296-62622154 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051328 Approved "Intracellular and membrane" Enzyme NA NA 990000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Non-specific - Basic cellular processes" 1 "HPA051328: AB_2681444" "unprognostic (1.55e-1)" "unprognostic (3.93e-2)" "unprognostic (8.45e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.11e-6)" "unprognostic (4.94e-2)" "unprognostic (2.42e-1)" "unprognostic (3.66e-2)" "unprognostic (1.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.58e-3)" "unprognostic (1.46e-3)" "unprognostic (6.00e-2)" "unprognostic (4.48e-2)" "unprognostic (2.58e-2)" B3GLCT "B3GALTL, B3Glc-T, B3GTL" ENSG00000187676 "Beta 3-glucosyltransferase" Q6Y288 13 31199975-31332276 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 51.4;Cardiomyocytes: 30.3;Excitatory neurons: 60.5;Inhibitory neurons: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (3.31e-2)" "unprognostic (2.53e-1)" "unprognostic (4.71e-2)" "unprognostic (6.17e-3)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.00e-1)" "unprognostic (2.91e-1)" "unprognostic (3.28e-3)" "unprognostic (6.74e-2)" "unprognostic (5.51e-3)" "unprognostic (2.26e-1)" "unprognostic (5.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.51e-1)" B3GNT3 "B3GN-T3, B3GNT-3, beta3Gn-T3, HP10328, TMEM3" ENSG00000179913 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3" Q9Y2A9 19 17794828-17813576 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.6;salivary gland: 30.4;stomach 1: 42.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 80.1;Cytotrophoblasts: 83.2;Distal enterocytes: 96.8;Intestinal goblet cells: 43.4;Paneth cells: 75.2;Proximal enterocytes: 58.0;Syncytiotrophoblasts: 70.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 64.9" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024298 Enhanced "Intracellular and membrane" Enzyme NA NA 74000 "Cluster 39: T-cells - T-cell receptor" "Cluster 45: Intestine - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA024298: AB_1845236" "unprognostic (1.10e-1)" "unprognostic (5.19e-2)" "unprognostic (1.84e-1)" "unprognostic (4.84e-3)" "unprognostic (1.10e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (3.26e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (7.38e-2)" "unprognostic (1.26e-1)" "unprognostic (7.10e-2)" "unprognostic (2.57e-2)" B3GNT6 B3Gn-T6 ENSG00000198488 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6" Q6ZMB0 11 77034398-77041973 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 21.0;salivary gland: 6.2;stomach 1: 24.2" "Group enriched" "Detected in some" 9 "Gastric mucus-secreting cells: 25.4;Intestinal goblet cells: 57.3" "Group enriched" "Detected in some" 14 "colorectal cancer: 6.3;lung cancer: 3.9;pancreatic cancer: 5.1;prostate cancer: 5.0;stomach cancer: 4.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.3;lung cancer: 1.8" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039805 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA039805: AB_2676690" "unprognostic (1.71e-1)" "prognostic favorable (2.31e-4)" "unprognostic (4.79e-2)" "unprognostic (5.42e-2)" "unprognostic (7.64e-2)" "unprognostic (1.95e-1)" "unprognostic (2.72e-1)" "unprognostic (1.23e-2)" "unprognostic (7.77e-2)" "unprognostic (2.19e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-1)" B3GNT7 beta3GnT7 ENSG00000156966 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" Q8NFL0 2 231395710-231401164 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 69.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 95.4;Distal enterocytes: 409.2;Enteroendocrine cells: 89.9;Intestinal goblet cells: 97.3;Paneth cells: 103.0;Undifferentiated cells: 149.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 32.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Fibroblast_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA013881, HPA035625, HPA035626" Enhanced Approved "Golgi apparatus,Mitotic spindle,Cytosol" "Intracellular and membrane" Enzyme Yes NA 3600000 "Cluster 14: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Golgi apparatus" "Mitotic spindle, Cytosol" "HPA013881: , HPA035625: AB_10601118, HPA035626: AB_2674707" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-3)" "unprognostic (1.46e-2)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "unprognostic (1.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.18e-2)" "unprognostic (5.82e-2)" "unprognostic (2.17e-2)" "unprognostic (7.77e-2)" "unprognostic (4.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.18e-1)" "prognostic favorable (6.00e-4)" "unprognostic (3.57e-1)" B3GNT8 "B3GALT7, beta3Gn-T8, BGALT15" ENSG00000177191 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8" Q7Z7M8 19 41425359-41428730 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 43.3;intestine: 19.2;vagina: 18.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 51.8;Distal enterocytes: 59.2;Intestinal goblet cells: 29.1;Paneth cells: 44.8;Proximal enterocytes: 63.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 117.8;eosinophil: 146.9;neutrophil: 198.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 198.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.3;Leukemia: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043669 Enhanced "Intracellular and membrane" Enzyme NA NA 57000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "HPA043669: AB_2678608" "unprognostic (6.89e-2)" "unprognostic (2.46e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (4.11e-4)" "unprognostic (6.44e-3)" "unprognostic (6.51e-3)" "unprognostic (1.84e-2)" "unprognostic (9.92e-3)" "unprognostic (7.30e-2)" "unprognostic (2.56e-2)" "prognostic favorable (9.31e-6)" "unprognostic (5.04e-2)" "unprognostic (2.62e-3)" "unprognostic (2.07e-1)" "unprognostic (6.16e-2)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" B3GNT9 MGC4655 ENSG00000237172 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9" Q6UX72 16 67148104-67150998 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 11.3;Peritubular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052743, HPA062734" Approved Approved "Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 1 "Golgi apparatus" "Nucleoli fibrillar center" "HPA052743: AB_2681934, HPA062734: AB_2684854" "unprognostic (2.56e-2)" "unprognostic (2.22e-1)" "unprognostic (2.34e-2)" "unprognostic (1.07e-1)" "unprognostic (6.58e-2)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.28e-2)" "unprognostic (3.01e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.51e-2)" "unprognostic (1.15e-1)" "unprognostic (4.96e-3)" "unprognostic (7.56e-3)" B4GALNT1 "beta1-4GalNAc-T, GALGT, SPG26" ENSG00000135454 "Beta-1,4-N-acetyl-galactosaminyltransferase 1" Q00973 12 57623409-57633239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 45.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.7;Excitatory neurons: 21.3;Horizontal cells: 23.3;Inhibitory neurons: 12.8;Schwann cells: 31.3" "Cancer enriched" "Detected in many" 6 "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 96.0" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008968 Enhanced "Intracellular and membrane" Enzyme NA NA 35000 "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "HPA008968: AB_1078253" "unprognostic (3.18e-1)" "unprognostic (8.34e-2)" "unprognostic (2.05e-2)" "unprognostic (3.33e-3)" "unprognostic (2.54e-1)" "unprognostic (2.70e-3)" "unprognostic (3.73e-5)" "unprognostic (1.26e-2)" "unprognostic (1.72e-1)" "unprognostic (2.66e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.18e-14)" "unprognostic (2.52e-2)" "unprognostic (1.81e-1)" "unprognostic (1.44e-2)" "unprognostic (4.92e-4)" B4GALNT3 "B4GalNac-T3, FLJ16224, FLJ40362" ENSG00000139044 "Beta-1,4-N-acetyl-galactosaminyltransferase 3" Q6L9W6 12 459939-563509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 59.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 49.7;Excitatory neurons: 31.4;Gastric mucus-secreting cells: 130.3;Glandular and luminal cells: 48.8;Late spermatids: 86.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011404 Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" "Golgi apparatus" Vesicles "HPA011404: AB_1845242" "unprognostic (2.38e-2)" "unprognostic (9.59e-3)" "unprognostic (1.38e-1)" "prognostic favorable (1.69e-10)" "unprognostic (4.22e-2)" "unprognostic (4.63e-2)" "unprognostic (1.46e-2)" "unprognostic (9.53e-3)" "unprognostic (3.29e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (9.99e-3)" "unprognostic (2.82e-1)" "unprognostic (2.48e-2)" "unprognostic (2.98e-1)" B4GALNT4 "FLJ25045, NGalNAc-T1" ENSG00000182272 "Beta-1,4-N-acetyl-galactosaminyltransferase 4" Q76KP1 11 369499-382117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.0;ovary: 26.9" "Cell type enhanced" "Detected in many" "Astrocytes: 126.3;Excitatory neurons: 30.2;Horizontal cells: 38.4;Inhibitory neurons: 31.0;Muller glia cells: 41.2;Oligodendrocyte precursor cells: 26.4;Oligodendrocytes: 30.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043276, HPA053126" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" Enzyme NA No "Cluster 22: Brain - Synaptic signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 47: Astrocytes - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA043276: , HPA053126: AB_2682049" "unprognostic (6.11e-2)" "unprognostic (7.82e-2)" "unprognostic (1.79e-1)" "unprognostic (6.92e-3)" "unprognostic (5.36e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-1)" "unprognostic (1.53e-1)" "unprognostic (1.69e-3)" "unprognostic (4.99e-3)" "unprognostic (1.52e-10)" "unprognostic (9.01e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-4)" "unprognostic (1.25e-1)" B4GALT1 "beta4Gal-T1, GGTB2" ENSG00000086062 "Beta-1,4-galactosyltransferase 1" P15291 9 33104082-33167356 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 310.7;Langerhans cells: 357.0;monocytes: 409.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 215.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010806, HPA010807" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 97000000 "Cluster 30: Non-specific - DNA binding" "Cluster 51: Thyroid gland - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus" "HPA010806: AB_1078255, HPA010807: AB_1078254" "unprognostic (7.57e-2)" "unprognostic (1.24e-2)" "unprognostic (2.09e-1)" "prognostic favorable (6.85e-7)" "unprognostic (1.83e-2)" "unprognostic (9.94e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.68e-3)" "unprognostic (2.78e-1)" "unprognostic (7.93e-3)" "unprognostic (4.98e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.46e-2)" B4GALT4 beta4Gal-T4 ENSG00000121578 "Beta-1,4-galactosyltransferase 4" O60513 3 119211732-119240946 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 74.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 141.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046819, HPA063546" Approved Supported "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Golgi apparatus" "HPA046819: AB_2679824, HPA063546: AB_2685036" "unprognostic (4.07e-2)" "unprognostic (1.78e-2)" "unprognostic (3.27e-2)" "unprognostic (1.14e-3)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (6.30e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-1)" "unprognostic (6.10e-3)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (2.37e-1)" "unprognostic (1.11e-1)" B4GALT5 beta4GalT-V ENSG00000158470 "Beta-1,4-galactosyltransferase 5" O43286 20 49632945-49713878 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 133.9;monocytes: 214.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077777 Approved Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 56: Non-specific - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Monocytes - Innate immune response" Vesicles "HPA077777: " "unprognostic (7.98e-2)" "unprognostic (5.27e-2)" "unprognostic (2.62e-1)" "unprognostic (1.88e-2)" "unprognostic (2.76e-1)" "unprognostic (1.61e-2)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (3.30e-2)" "unprognostic (5.41e-1)" "unprognostic (2.07e-1)" "unprognostic (2.69e-2)" B4GALT6 beta4GalT-VI ENSG00000118276 "Beta-1,4-galactosyltransferase 6" Q9UBX8 18 31622246-31685836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 25.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 90.8;Excitatory neurons: 69.1;Horizontal cells: 34.0;Inhibitory neurons: 99.3;Oligodendrocyte precursor cells: 76.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.4" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.4" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020701, HPA058284" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 25: Bipolar cells - Visual perception" "CAB020701: , HPA058284: AB_2683668" "unprognostic (3.79e-1)" "unprognostic (4.52e-1)" "unprognostic (6.54e-3)" "unprognostic (2.23e-4)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.31e-2)" "unprognostic (4.50e-2)" "unprognostic (5.18e-1)" "unprognostic (1.13e-1)" "prognostic favorable (5.65e-4)" "unprognostic (2.77e-1)" "prognostic favorable (6.40e-5)" "unprognostic (5.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.10e-2)" "unprognostic (4.00e-1)" B4GAT1 "B3GN-T1, B3GNT1, B3GNT6, BETA3GNTI, iGAT, IGnT" ENSG00000174684 "Beta-1,4-glucuronyltransferase 1" O43505 11 66345374-66347629 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 199.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 117.2;Horizontal cells: 81.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015484 Uncertain "Intracellular and membrane" Enzyme NA NA 57000000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "HPA015484: AB_1845235" "unprognostic (1.80e-1)" "unprognostic (7.20e-2)" "unprognostic (1.70e-1)" "unprognostic (3.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.45e-1)" "unprognostic (9.23e-2)" "unprognostic (1.59e-1)" "unprognostic (2.65e-2)" "unprognostic (3.43e-3)" "prognostic favorable (3.55e-5)" "unprognostic (2.20e-1)" "unprognostic (3.50e-1)" "unprognostic (1.23e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-1)" "unprognostic (2.76e-3)" B9D1 "B9, EPPB9, MKS9, MKSR-1" ENSG00000108641 "B9 domain containing 1" Q9UPM9 17 19334308-19378193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 89.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 132.0;Early spermatids: 265.0;Late spermatids: 179.0;Spermatocytes: 124.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022957 Approved "Intracellular and membrane" Other NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" 3 "HPA022957: AB_1848220" "unprognostic (3.13e-2)" "unprognostic (3.78e-2)" "unprognostic (2.16e-1)" "unprognostic (3.66e-3)" "unprognostic (9.82e-3)" "unprognostic (1.37e-2)" "unprognostic (6.57e-3)" "unprognostic (1.32e-1)" "unprognostic (1.29e-1)" "unprognostic (1.46e-2)" "unprognostic (1.83e-2)" "unprognostic (2.21e-1)" "prognostic favorable (4.14e-4)" "unprognostic (3.21e-2)" "unprognostic (1.27e-1)" "unprognostic (1.23e-1)" "unprognostic (1.18e-3)" BACE2 "AEPLC, ALP56, CEAP1, DRAP" ENSG00000182240 "Beta-secretase 2" Q9Y5Z0 21 41167801-41282530 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 26.0" "Cell type enhanced" "Detected in many" "Melanocytes: 261.1;Mucus glandular cells: 248.8;Syncytiotrophoblasts: 521.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.9;eosinophil: 5.2" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.2" "Cancer enhanced" "Detected in many" "skin cancer: 55.9" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblast_2, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035416 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 48: Stomach - Proteolysis" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 14 "HPA035416: AB_2732467" "unprognostic (1.71e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (5.23e-2)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.86e-4)" "unprognostic (1.52e-2)" "unprognostic (2.58e-2)" "unprognostic (2.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.49e-1)" "unprognostic (3.46e-2)" "unprognostic (8.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.04e-1)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (5.83e-2)" BAG6 "BAT3, D6S52E, G3, Scythe" ENSG00000204463 "BAG cochaperone 6" P46379 6 31639028-31652705 "Predicted intracellular proteins" "Apoptosis, Differentiation, Immunity, Spermatogenesis, Transport" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 215.2;Late spermatids: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020704, HPA045116, HPA053291" Enhanced Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" Transport NA NA 26000 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" 11 "Nucleoplasm, Cytosol" "CAB020704: , HPA045116: AB_2679220, HPA053291: AB_2682103" "unprognostic (7.32e-2)" "unprognostic (2.96e-2)" "unprognostic (3.43e-1)" "unprognostic (7.67e-3)" "unprognostic (2.61e-1)" "unprognostic (6.00e-2)" "unprognostic (1.07e-3)" "unprognostic (2.14e-1)" "unprognostic (4.46e-1)" "unprognostic (1.34e-1)" "unprognostic (2.88e-2)" "unprognostic (9.98e-2)" "unprognostic (1.08e-3)" "unprognostic (2.04e-1)" "unprognostic (1.82e-2)" "unprognostic (6.05e-2)" "unprognostic (8.16e-2)" BCAN "BEHAB, CSPG7, MGC13038" ENSG00000132692 Brevican Q96GW7 1 156641390-156659532 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "brain: 245.5" "Group enriched" "Detected in some" 4 "Astrocytes: 129.1;Melanocytes: 271.4;Oligodendrocyte precursor cells: 270.3" "Cancer enriched" "Detected in many" 5 "glioma: 348.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "basophil: 7.8" "Lineage enriched" "Detected in single" 24 "granulocytes: 7.8" "Low cancer specificity" "Detected in all" "Skin - Melanocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007865, CAB025862" Enhanced Supported "Secreted in brain" "No annotated function" NA NA 120000 "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "CAB025862: , HPA007865: AB_1078299" "unprognostic (7.14e-2)" "unprognostic (3.14e-1)" "unprognostic (1.95e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (9.03e-2)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (4.80e-2)" "unprognostic (6.87e-2)" "unprognostic (1.65e-1)" "unprognostic (1.30e-2)" "unprognostic (9.47e-3)" "unprognostic (2.76e-2)" "unprognostic (8.54e-2)" "unprognostic (5.40e-1)" "unprognostic (1.90e-1)" BCHE "CHE1, CHE2, E1" ENSG00000114200 Butyrylcholinesterase P06276 3 165772904-165837462 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 508.2" "Group enriched" "Detected in many" 7 "Hepatocytes: 505.6;Mesothelial cells: 169.6;Oligodendrocyte precursor cells: 197.2" "Group enriched" "Detected in many" 6 "glioma: 24.0;liver cancer: 13.7;melanoma: 18.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" HPA001560 Approved "Secreted to blood" Enzyme NA NA 9400000000 "Cluster 83: Liver - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 43: Hepatocytes - Metabolism" 5 "HPA001560: AB_1078271" "unprognostic (4.74e-2)" "unprognostic (2.00e-1)" "unprognostic (9.21e-4)" "unprognostic (8.19e-8)" "unprognostic (2.66e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.44e-1)" "unprognostic (5.04e-2)" "unprognostic (6.15e-2)" "unprognostic (9.59e-2)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" "unprognostic (3.18e-3)" "unprognostic (4.46e-5)" "unprognostic (2.17e-2)" "unprognostic (5.92e-2)" "unprognostic (4.26e-4)" BCKDHB ENSG00000083123 "Branched chain keto acid dehydrogenase E1 subunit beta" P21953 6 80106647-80346270 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 75.9" "Cell type enhanced" "Detected in all" "Astrocytes: 281.1;Early spermatids: 164.4;Oligodendrocytes: 94.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031580, HPA031956" Approved Supported Nucleoplasm,Nucleoli,Mitochondria "Intracellular and membrane" Enzyme Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 47: Astrocytes - Unknown function" 2 Mitochondria "Nucleoplasm, Nucleoli" "HPA031580: AB_10696054, HPA031956: " "unprognostic (4.23e-1)" "unprognostic (1.61e-1)" "unprognostic (9.50e-3)" "unprognostic (9.37e-3)" "unprognostic (1.66e-1)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (2.30e-2)" "unprognostic (1.94e-1)" "unprognostic (7.32e-3)" "unprognostic (2.67e-1)" "unprognostic (4.65e-2)" "prognostic favorable (5.54e-9)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (1.49e-2)" BDNF ENSG00000176697 "Brain derived neurotrophic factor" P23560 11 27654893-27722058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 20.5;Bipolar cells: 9.6;Cardiomyocytes: 11.4;Excitatory neurons: 21.5;Granulosa cells: 20.8;Oocytes: 11.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 27.6" "Lung - Alveolar cells type 1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB009564 Enhanced "Secreted to blood" "Growth factor" NA Yes 16000000 24000 "Cluster 30: Heart muscle - Heart development" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 15: Non-specific - Mixed function" 1 "CAB009564: AB_2064213" "unprognostic (1.25e-2)" "unprognostic (2.84e-1)" "unprognostic (4.35e-2)" "unprognostic (2.54e-2)" "unprognostic (1.01e-2)" "unprognostic (6.82e-2)" "unprognostic (2.39e-2)" "unprognostic (2.21e-1)" "unprognostic (3.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (3.22e-2)" "unprognostic (3.88e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (2.84e-3)" BGLAP OCN ENSG00000242252 "Bone gamma-carboxyglutamate protein" P02818 1 156242184-156243317 "FDA approved drug targets, Predicted secreted proteins" Biomineralization "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 7.1;intestine: 8.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.1;Serous glandular cells: 2.3;Sertoli cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "NK-cell: 1.8;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 17 "dendritic cells: 1.6;NK-cells: 1.8" "Cancer enhanced" "Detected in some" "Leukemia: 5.8;Myeloma: 14.4" "Colon - Enteric glia cells" "Region enriched" "Detected in single" 7 "olfactory bulb: 5.3" "Low region specificity" "Detected in all" "Secreted to blood" Other NA NA 15500000 2200000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "unprognostic (2.50e-2)" "unprognostic (4.49e-2)" "unprognostic (3.82e-4)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (8.44e-5)" "unprognostic (2.63e-2)" "unprognostic (6.54e-2)" "unprognostic (5.64e-2)" "unprognostic (2.00e-1)" "unprognostic (1.53e-3)" "unprognostic (4.70e-2)" "unprognostic (9.67e-6)" "unprognostic (3.02e-2)" "unprognostic (1.72e-1)" "unprognostic (4.34e-2)" "unprognostic (8.64e-3)" BGN "DSPG1, SLRR1A" ENSG00000182492 Biglycan P21810 X 153494980-153509546 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 769.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 239.9;Pancreatic endocrine cells: 161.3;Peritubular cells: 649.2;Sertoli cells: 508.6;Smooth muscle cells: 445.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 147.9;thyroid cancer: 165.4" "Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003157, CAB003678" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" "No annotated function" NA NA 3300000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 3 "Golgi apparatus" "Endoplasmic reticulum" "CAB003678: AB_425325, HPA003157: AB_1078282" "unprognostic (1.74e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-3)" "unprognostic (3.60e-1)" "unprognostic (5.42e-2)" "unprognostic (3.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.22e-2)" "unprognostic (1.76e-3)" "unprognostic (1.30e-2)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (6.00e-8)" "unprognostic (7.05e-3)" "unprognostic (2.40e-2)" "unprognostic (5.66e-2)" "unprognostic (2.57e-3)" BLTP2 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, Hob, KIAA0100, MGC111488" ENSG00000007202 "Bridge-like lipid transfer protein family member 2" Q14667 17 28614446-28645454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" "Intracellular and membrane" "No annotated function" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Non-specific - DNA binding" "Nuclear speckles, Cytosol" "HPA042781: AB_10797020" "unprognostic (1.91e-1)" "unprognostic (1.03e-2)" "unprognostic (3.47e-2)" "unprognostic (5.26e-3)" "unprognostic (2.43e-1)" "unprognostic (6.89e-2)" "prognostic unfavorable (3.47e-5)" "unprognostic (4.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-3)" "unprognostic (2.40e-2)" "unprognostic (2.53e-1)" "unprognostic (4.24e-3)" "unprognostic (7.58e-2)" "unprognostic (5.84e-2)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" BMAL1 "ARNTL, ARNTL1, bHLHe5, JAP3, MOP3, PASD3" ENSG00000133794 "Basic helix-loop-helix ARNT like 1" O00327 11 13276652-13387266 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 61.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045962, HPA050938" Supported Supported Nucleoplasm,Vesicles "Intracellular and membrane" Transcription NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 Nucleoplasm Vesicles "CAB045962: AB_11124144, HPA050938: AB_2681282" "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (9.00e-2)" "unprognostic (1.77e-1)" "unprognostic (3.72e-1)" "unprognostic (3.76e-2)" "unprognostic (8.92e-2)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "unprognostic (7.80e-2)" "unprognostic (1.34e-2)" "unprognostic (2.10e-1)" "unprognostic (2.77e-2)" "unprognostic (3.11e-2)" "unprognostic (7.08e-2)" BMP1 "BMP-1, PCOLC" ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22165140-22212326 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 36.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" Cytokine NA NA 9200000 "Cluster 33: Non-specific - ATP binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 54: Immune cells - T cell receptor" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 4 "HPA014572: AB_1845390" "unprognostic (1.24e-1)" "unprognostic (8.01e-2)" "unprognostic (3.75e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-2)" "unprognostic (6.76e-2)" "unprognostic (9.53e-2)" "unprognostic (2.64e-3)" "unprognostic (1.66e-1)" "unprognostic (9.75e-3)" "unprognostic (7.05e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.37e-9)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-3)" "unprognostic (3.34e-2)" BMP10 ENSG00000163217 "Bone morphogenetic protein 10" O95393 2 68860909-68871397 "Predicted secreted proteins" "Cell adhesion" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 67 "heart muscle: 432.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.4;Kupffer cells: 1.7;Late spermatids: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 27 "Gastric cancer: 9.4;Rhabdoid: 2.9" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" Cytokine NA NA 230000 "Cluster 30: Heart muscle - Heart development" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 51 "unprognostic (1.74e-1)" BMP15 GDF9B ENSG00000130385 "Bone morphogenetic protein 15" O95972 X 50910735-50916641 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant, Premature ovarian failure" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 15 "Early spermatids: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Cytokine NA NA "Cluster 18: Early spermatids - Unknown function" BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.9;Alveolar cells type 2: 127.0;Basal keratinocytes: 109.2;Distal enterocytes: 80.0;Lymphatic endothelial cells: 116.5;Suprabasal keratinocytes: 71.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 30.7" "Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" Cytokine NA NA 24400 21000 "Cluster 57: Lung - Lung function" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 4 Vesicles "CAB078457: AB_2532532, HPA058610: AB_2683777" "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" BMP3 ENSG00000152785 "Bone morphogenetic protein 3" P12645 4 81030708-81057627 "Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.0;lung: 5.3;ovary: 5.2;urinary bladder: 9.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 18.1;Club cells: 13.3;Distal enterocytes: 39.7;Mucus glandular cells: 15.7;Paneth cells: 37.3;Proximal enterocytes: 25.0;Salivary duct cells: 15.2;Undifferentiated cells: 14.7" "Group enriched" "Detected in some" 4 "lung cancer: 4.2;urothelial cancer: 7.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.9;lymphoma: 6.6" "Lung - Alveolar cells type 2, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" Cytokine NA NA "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 5: Enterocytes - Absorption" "unprognostic (5.21e-3)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (3.36e-2)" "unprognostic (2.73e-3)" "unprognostic (9.11e-2)" "unprognostic (2.35e-1)" "unprognostic (1.94e-1)" "unprognostic (1.16e-4)" "unprognostic (2.26e-2)" "unprognostic (3.86e-1)" "unprognostic (1.11e-1)" "unprognostic (4.22e-2)" BMP4 BMP2B ENSG00000125378 "Bone morphogenetic protein 4" P12644 14 53949736-53958761 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 76.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 30.4;Cytotrophoblasts: 29.5;Fibroblasts: 44.8;Syncytiotrophoblasts: 39.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 28.9" "Region enriched" "Detected in all" 6 "choroid plexus: 65.3" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.9" "Group enriched" "Detected in many" 12 "monocytes: 1.9;T-cells: 1.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 279.2" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006863, HPA066235" Uncertain "Secreted to blood" Cytokine NA NA 162000000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 53: Fibroblasts - ECM organization" 1 "CAB006863: , HPA066235: AB_2685641" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "unprognostic (3.39e-2)" "unprognostic (3.32e-1)" "unprognostic (2.78e-2)" "unprognostic (3.11e-1)" "unprognostic (3.45e-3)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (7.06e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-3)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (1.24e-1)" BMP5 ENSG00000112175 "Bone morphogenetic protein 5" P22003 6 55753653-55875590 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 68.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 15.2;Fibroblasts: 11.1;Microglial cells: 25.0;Pancreatic endocrine cells: 39.1;Skeletal myocytes: 8.8;Smooth muscle cells: 21.7" "Cancer enhanced" "Detected in many" "lung cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 15.3" "Liver - Hepatic stellate cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" Cytokine NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" "unprognostic (2.84e-4)" "unprognostic (9.07e-4)" "unprognostic (3.50e-1)" "unprognostic (1.27e-1)" "unprognostic (6.21e-2)" "unprognostic (1.58e-1)" "unprognostic (2.39e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (6.76e-2)" "unprognostic (4.43e-3)" "unprognostic (3.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.30e-1)" "unprognostic (4.76e-2)" BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 19.7" "Cell type enhanced" "Detected in some" "Adipocytes: 42.9;Endothelial cells: 21.6;Inhibitory neurons: 21.7;Microglial cells: 70.7;Oocytes: 110.3;Plasma cells: 30.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "Myeloma: 42.2;Rhabdoid: 30.5" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Skin - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Uncertain Mitochondria "Secreted to blood" Cytokine No No 4970000 46000 "Cluster 46: Basophils - Proteolysis" "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" BMP7 OP-1 ENSG00000101144 "Bone morphogenetic protein 7" P18075 20 57168753-57266641 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 35.2;thyroid gland: 44.6" "Cell type enhanced" "Detected in many" "Astrocytes: 70.3;Basal keratinocytes: 47.8;Basal squamous epithelial cells: 41.9;Cytotrophoblasts: 137.6;Oligodendrocyte precursor cells: 69.8;Squamous epithelial cells: 43.8;Syncytiotrophoblasts: 55.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061339 Approved Nucleoplasm,Vesicles "Secreted to blood" Cytokine NA NA 248000 "Cluster 34: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Cytotrophoblasts - Mitochondria" 13 Vesicles Nucleoplasm "HPA061339: " "unprognostic (1.67e-1)" "unprognostic (9.72e-3)" "unprognostic (9.67e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.62e-1)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (4.63e-3)" "unprognostic (4.03e-2)" "unprognostic (1.09e-2)" "unprognostic (3.82e-2)" "unprognostic (4.30e-2)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (1.59e-1)" BMP8A OP-2 ENSG00000183682 "Bone morphogenetic protein 8a" Q7Z5Y6 1 39491636-39529869 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 16 "thyroid gland: 89.1" "Cell type enriched" "Detected in some" 7 "Late spermatids: 169.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 8.2;prostate cancer: 7.3" "Testis - Late spermatids" HPA047254 Approved Vesicles "Secreted to blood" Cytokine NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Late spermatids - Unknown function" Vesicles "HPA047254: " "unprognostic (9.62e-3)" "unprognostic (2.11e-2)" "unprognostic (7.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.91e-3)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (2.95e-9)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" BMP8B "BMP8, OP-2" ENSG00000116985 "Bone morphogenetic protein 8b" P34820 1 39757182-39788865 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Early spermatids: 36.2;Late spermatids: 96.3;Plasma cells: 38.6;Schwann cells: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 38.6" HPA047254 Approved Vesicles "Secreted to blood" Cytokine NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" Vesicles "HPA047254: " "unprognostic (1.53e-3)" "unprognostic (7.29e-2)" "unprognostic (2.18e-1)" "unprognostic (6.64e-3)" "unprognostic (8.79e-2)" "unprognostic (3.44e-2)" "unprognostic (7.27e-2)" "unprognostic (7.56e-2)" "unprognostic (1.88e-1)" "unprognostic (7.41e-2)" "unprognostic (2.68e-1)" "unprognostic (4.72e-4)" "unprognostic (1.79e-2)" "unprognostic (3.15e-1)" "unprognostic (9.67e-2)" "unprognostic (8.68e-3)" "unprognostic (4.82e-1)" BMPER "CRIM3, Cv2" ENSG00000164619 "BMP binding endothelial regulator" Q8N8U9 7 33904308-34156427 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 277.1;Inhibitory neurons: 86.2;Oligodendrocyte precursor cells: 98.6" "Cancer enhanced" "Detected in some" "glioma: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 11.5" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (4.50e-2)" "unprognostic (2.68e-1)" "unprognostic (2.83e-2)" "unprognostic (3.19e-2)" "unprognostic (1.93e-1)" "unprognostic (1.96e-4)" "unprognostic (5.34e-3)" "unprognostic (3.10e-1)" "unprognostic (9.98e-3)" "unprognostic (3.50e-3)" "unprognostic (8.01e-4)" "unprognostic (1.96e-1)" "unprognostic (5.67e-5)" "unprognostic (2.54e-1)" "unprognostic (2.62e-1)" "unprognostic (2.06e-2)" "unprognostic (3.47e-3)" BOC "Boi, CDON2" ENSG00000144857 "BOC cell adhesion associated, oncogene regulated" Q9BWV1 3 113211003-113287459 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 68.1;Basal squamous epithelial cells: 58.7;Fibroblasts: 59.9;Leydig cells: 82.7;Peritubular cells: 44.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025806 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA No 7900000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "Nuclear bodies, Plasma membrane" Nucleoplasm "CAB025806: " "unprognostic (6.89e-3)" "unprognostic (1.34e-2)" "unprognostic (2.62e-3)" "unprognostic (1.03e-2)" "unprognostic (5.03e-3)" "prognostic favorable (4.89e-4)" "unprognostic (8.66e-5)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (4.78e-3)" "unprognostic (3.42e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-3)" "unprognostic (4.94e-3)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.18e-5)" BOLA1 CGI-143 ENSG00000178096 "BolA family member 1" Q9Y3E2 1 149887890-149900798 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007005 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 7 "HPA007005: AB_1078294" "unprognostic (5.73e-2)" "unprognostic (9.86e-3)" "unprognostic (8.84e-2)" "unprognostic (8.18e-2)" "unprognostic (9.33e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.67e-2)" "unprognostic (2.19e-1)" "prognostic favorable (6.41e-4)" "unprognostic (3.14e-3)" "unprognostic (3.36e-2)" "unprognostic (2.22e-1)" "unprognostic (8.73e-2)" "unprognostic (1.31e-1)" "unprognostic (9.58e-2)" "unprognostic (1.93e-3)" BPI BPIFD1 ENSG00000101425 "Bactericidal permeability increasing protein" P17213 20 38304150-38337505 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 89 "bone marrow: 1486.2" "Group enriched" "Detected in some" 54 "Early spermatids: 180.0;Late spermatids: 236.2;Proximal tubular cells: 87.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "classical monocyte: 14.5;neutrophil: 7.1" "Group enriched" "Detected in many" 17 "granulocytes: 7.1;monocytes: 14.5" "Cancer enriched" "Detected in some" 4 "Leukemia: 20.4" "Liver - Erythroid cells, Lung - Neutrophil_1, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA061284 Enhanced "Secreted to blood" Immunity NA NA 7290000 78000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 11: Late spermatids - Unknown function" "HPA061284: AB_2684465" "unprognostic (9.30e-4)" "unprognostic (5.49e-2)" "unprognostic (1.97e-1)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (1.56e-1)" "unprognostic (4.50e-2)" "unprognostic (1.98e-1)" "unprognostic (3.07e-2)" "unprognostic (1.14e-1)" "unprognostic (2.60e-2)" "unprognostic (1.50e-1)" "unprognostic (8.83e-6)" "unprognostic (2.66e-4)" "unprognostic (9.29e-2)" "unprognostic (2.32e-2)" "unprognostic (9.47e-3)" BPIFA1 "bA49G10.5, LUNX, PLUNC, SPLUNC1" ENSG00000198183 "BPI fold containing family A member 1" Q9NP55 20 33235995-33243311 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 6.0;lung: 17.7;pituitary gland: 11.8" "Group enriched" "Detected in some" 5 "Club cells: 960.0;Ionocytes: 617.4;Serous glandular cells: 535.7" "Cancer enriched" "Detected in many" 27 "lung cancer: 262.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 28 "pancreatic cancer: 28.5" "Lung - Respiratory ciliated cells" "Region enriched" "Detected in single" 10 "cerebellum: 2.0" "Not detected" "Not detected" CAB025669 Supported "Secreted in other tissues" Immunity NA NA 1200000 "Cluster 57: Lung - Lung function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Respiratory epithelial cells - Unknown function" 38 "CAB025669: " "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (3.65e-1)" "unprognostic (1.80e-1)" BPIFA2 "bA49G10.1, C20orf70, PSP, SPLUNC2" ENSG00000131050 "BPI fold containing family A member 2" Q96DR5 20 33161768-33181412 "Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1611 "salivary gland: 6665.1" "Cell type enriched" "Detected in some" 19 "Serous glandular cells: 5236.8" "Group enriched" "Detected in some" 4 "lung cancer: 2.6;pancreatic cancer: 2.9;stomach cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.6;lung cancer: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA044006 Enhanced "Secreted to digestive system" Defense NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 7: Liver cancer - Metabolism" "Cluster 75: Serous glandular cells - Salivary secretion" 2 "HPA044006: AB_10963580" "unprognostic (9.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (3.56e-2)" "unprognostic (3.03e-2)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (1.04e-1)" "unprognostic (6.14e-4)" BPIFA3 "bA49G10.4, C20orf71, SPLUNC3" ENSG00000131059 "BPI fold containing family A member 3" Q9BQP9 20 33217310-33227806 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 522 "testis: 52.2" "Cell type enriched" "Detected in some" 5 "Late spermatids: 3086.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA062708 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 36: Late spermatids - Unknown function" "HPA062708: AB_2684843" BPIFB1 "bA49G10.6, C20orf114, dJ1187J4.1, LPLUNC1, MGC14597, VEMSGP" ENSG00000125999 "BPI fold containing family B member 1" Q8TDL5 20 33273480-33309871 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 546.4;salivary gland: 264.3;stomach 1: 499.1" "Group enriched" "Detected in some" 7 "Club cells: 7690.7;Ionocytes: 4098.2" "Cancer enhanced" "Detected in many" "stomach cancer: 75.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "breast cancer: 122.7" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 6 "olfactory bulb: 4.8" "Low region specificity" "Detected in many" HPA024256 Enhanced "Secreted in other tissues" Immunity NA NA 2700000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA024256: AB_1845664" "unprognostic (2.42e-1)" "unprognostic (5.41e-2)" "unprognostic (3.67e-2)" "unprognostic (3.09e-1)" "unprognostic (6.72e-2)" "unprognostic (3.43e-2)" "unprognostic (9.37e-3)" "unprognostic (1.14e-1)" "unprognostic (2.82e-1)" "unprognostic (4.00e-2)" "unprognostic (9.01e-2)" "unprognostic (1.36e-7)" "unprognostic (3.30e-1)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" BPIFB2 "BPIL1, C20orf184, dJ726C3.2, LPLUNC2" ENSG00000078898 "BPI fold containing family B member 2" Q8N4F0 20 33007704-33023703 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "salivary gland: 2226.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 6.3;Breast myoepithelial cells: 14.1;Club cells: 9.2;Early spermatids: 5.6;Late spermatids: 9.4;Prostatic glandular cells: 4.5;Serous glandular cells: 14.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "breast cancer: 13.5;liver cancer: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049491, HPA060121" Enhanced Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA 36000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" Vesicles "HPA049491: AB_2680792, HPA060121: AB_2684207" "unprognostic (1.94e-1)" "prognostic favorable (1.97e-5)" "unprognostic (2.24e-4)" "unprognostic (9.48e-2)" "unprognostic (9.81e-2)" "unprognostic (2.02e-3)" "unprognostic (1.72e-2)" "unprognostic (2.71e-1)" "unprognostic (9.28e-2)" "unprognostic (5.35e-1)" "unprognostic (8.19e-2)" BPIFB3 "C20orf185, dJ726C3.4, LPLUNC3, RYA3" ENSG00000186190 "BPI fold containing family B member 3" P59826 20 33053903-33073847 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Late spermatids: 1.9" "Cancer enriched" "Detected in single" 7 "ovarian cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045741 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 5: Rhabdoid - Unknown function" "Cluster 57: Platelets - Hemostasis" 2 "HPA045741: AB_2679439" "unprognostic (4.33e-2)" "unprognostic (1.06e-3)" BPIFB4 "C20orf186, dJ726C3.5, LPLUNC4" ENSG00000186191 "BPI fold containing family B member 4" P59827 20 33079643-33111751 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "pituitary gland: 8.2" "Group enriched" "Detected in some" 5 "Basal respiratory cells: 2.6;Ionocytes: 1.8;Oocytes: 3.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "choroid plexus: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA047388 Approved "Actin filaments,Cytosol" "Secreted - unknown location" "No annotated function" NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Respiratory epithelial cells - Unknown function" "Actin filaments, Cytosol" "HPA047388: " "unprognostic (1.32e-1)" "unprognostic (1.16e-1)" "unprognostic (1.61e-1)" "unprognostic (2.75e-2)" "unprognostic (1.31e-3)" "unprognostic (4.70e-2)" "unprognostic (3.42e-2)" "unprognostic (2.03e-1)" "unprognostic (3.98e-4)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (8.97e-2)" BPIFB6 "BPIL3, LPLUNC6" ENSG00000167104 "BPI fold containing family B member 6" Q8NFQ5 20 33031648-33044047 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 32 "salivary gland: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043057 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 27: Breast cancer - Unknown function" "HPA043057: AB_10796683" BPIFC "BPIL2, dJ149A16.7" ENSG00000184459 "BPI fold containing family C" Q8NFQ6 22 32413845-32464484 "Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skin 1: 44.2" "Group enriched" "Detected in some" 6 "Early spermatids: 25.4;Late spermatids: 11.5;Suprabasal keratinocytes: 7.2" "Group enriched" "Detected in some" 11 "head and neck cancer: 1.6;melanoma: 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "basophil: 1.5" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.5" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted in other tissues" Immunity NA NA "Cluster 13: Skin - Cornification" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 18: Early spermatids - Unknown function" "unprognostic (2.74e-1)" "unprognostic (3.48e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (2.58e-1)" "unprognostic (3.48e-2)" "unprognostic (2.74e-1)" "unprognostic (2.58e-1)" "unprognostic (2.76e-3)" "unprognostic (1.41e-2)" "unprognostic (2.80e-1)" BRINP1 "DBC1, DBCCR1, FAM5A" ENSG00000078725 "BMP/retinoic acid inducible neural specific 1" O60477 9 119153458-119369435 "Predicted intracellular proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 38.8" "Group enriched" "Detected in some" 6 "Astrocytes: 169.7;Excitatory neurons: 276.1;Inhibitory neurons: 156.0;Oligodendrocyte precursor cells: 192.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 5.5" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038828 Approved Uncertain Microtubules "Intracellular and membrane" Other NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 1 Microtubules "HPA038828: AB_10670909" "unprognostic (8.60e-5)" "unprognostic (2.31e-2)" "unprognostic (1.24e-1)" "unprognostic (5.09e-5)" "unprognostic (1.12e-1)" "unprognostic (1.14e-2)" "unprognostic (1.37e-1)" "unprognostic (2.98e-1)" "unprognostic (1.76e-1)" "unprognostic (1.02e-1)" "unprognostic (2.28e-4)" "unprognostic (1.51e-2)" "unprognostic (5.06e-3)" "unprognostic (1.39e-3)" "unprognostic (1.56e-1)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" BRINP2 "DBCCR1L2, FAM5B" ENSG00000198797 "BMP/retinoic acid inducible neural specific 2" Q9C0B6 1 177170958-177282422 "Predicted secreted proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 9.3;brain: 31.1" "Group enriched" "Detected in some" 4 "Astrocytes: 114.9;Excitatory neurons: 112.9;Inhibitory neurons: 142.1;Oligodendrocyte precursor cells: 90.6" "Cancer enriched" "Detected in some" 5 "glioma: 11.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050681 Uncertain "Secreted in other tissues" Other NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 65: Neurons - Synaptic function" "HPA050681: " "unprognostic (7.78e-2)" "unprognostic (4.49e-1)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.43e-2)" "unprognostic (1.77e-1)" "unprognostic (5.77e-2)" "unprognostic (1.23e-2)" "unprognostic (1.95e-2)" "unprognostic (2.20e-4)" "unprognostic (8.95e-2)" "unprognostic (1.78e-2)" "unprognostic (2.60e-3)" "unprognostic (1.17e-1)" "unprognostic (2.60e-2)" "unprognostic (4.82e-3)" BRINP3 "DBCCR1L, DBCCR1L1, FAM5C" ENSG00000162670 "BMP/retinoic acid inducible neural specific 3" Q76B58 1 190097658-190478404 "Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8;intestine: 17.4" "Cell type enhanced" "Detected in some" "Astrocytes: 253.0;Excitatory neurons: 322.5;Inhibitory neurons: 124.1;Oligodendrocyte precursor cells: 1012.7" "Group enriched" "Detected in some" 14 "breast cancer: 3.4;glioma: 8.6;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 11.2;Rhabdoid: 20.8" "Lung - Fibroblast_2, Prostate - Prostate glandular cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054693 Uncertain "Secreted in other tissues" Other NA NA "Cluster 25: Small intestine - Absorption" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA054693: AB_2682575" "unprognostic (3.18e-2)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" "unprognostic (8.25e-2)" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (9.84e-2)" "unprognostic (4.58e-3)" BSPH1 "BSP1, ELSPBP2" ENSG00000188334 "Binder of sperm protein homolog 1" Q075Z2 19 47968046-47992170 "Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "epididymis: 373.6" "Cell type enhanced" "Detected in single" "Bipolar cells: 2.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048335 Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 2: Neurons - Nucleosome" "Cluster 38: Non-specific - Transcription" "Cluster 25: Bipolar cells - Visual perception" "HPA048335: AB_2732546" BST1 "BST-1, cADPR2, CD157" ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 138.1;intestine: 47.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 61.4;Kupffer cells: 31.0;Proximal enterocytes: 79.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 258.3;neutrophil: 294.2" "Group enriched" "Detected in many" 94 "dendritic cells: 79.0;granulocytes: 294.2;monocytes: 258.3" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" Enzyme NA NA 190000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 29: Monocytes - Innate immune response" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" BTBD17 "BTBD17A, LGALS3BPL, TANGO10A" ENSG00000204347 "BTB domain containing 17" A6NE02 17 74356416-74361868 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "brain: 7.4" "Cell type enhanced" "Detected in some" "Astrocytes: 4.0;Bipolar cells: 1.3;Gastric mucus-secreting cells: 1.8;Horizontal cells: 6.3;Late spermatids: 3.7;Muller glia cells: 1.6;Oligodendrocyte precursor cells: 3.3" "Cancer enriched" "Detected in some" 5 "glioma: 9.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 10.9;lung cancer: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA025022 Approved "Secreted in brain" "No annotated function" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Late spermatids - Unknown function" "HPA025022: AB_2067352" "unprognostic (2.63e-1)" "unprognostic (2.77e-1)" "unprognostic (4.82e-5)" "unprognostic (3.89e-2)" "unprognostic (2.55e-1)" "unprognostic (9.89e-3)" BTBD6 BDPL ENSG00000184887 "BTB domain containing 6" Q96KE9 14 105248533-105251093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 158.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031355 Approved Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 33: Non-specific - DNA binding" 1 Nucleoplasm "HPA031355: AB_10611812" "prognostic favorable (1.11e-4)" "unprognostic (2.01e-2)" "unprognostic (2.65e-1)" "unprognostic (1.97e-2)" "unprognostic (2.69e-1)" "unprognostic (2.58e-1)" "unprognostic (2.23e-2)" "unprognostic (4.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-1)" "prognostic favorable (2.25e-4)" "unprognostic (8.48e-3)" "prognostic favorable (6.51e-5)" "unprognostic (6.55e-2)" "unprognostic (3.22e-1)" "unprognostic (6.86e-2)" "unprognostic (9.85e-2)" BTC ENSG00000174808 Betacellulin P35070 4 74744759-74794523 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 22.1;Granulosa cells: 17.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.7" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" "Growth factor" NA NA 314000 "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Ciliated cells - Cilium assembly" 7 "unprognostic (7.36e-2)" "unprognostic (4.99e-2)" "unprognostic (7.04e-2)" "unprognostic (7.76e-3)" "unprognostic (3.87e-3)" "unprognostic (1.01e-3)" "unprognostic (1.05e-1)" "unprognostic (7.17e-3)" "unprognostic (2.68e-2)" "unprognostic (8.81e-2)" "unprognostic (1.50e-2)" "unprognostic (5.35e-1)" "prognostic favorable (6.10e-5)" "unprognostic (2.33e-1)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (2.31e-3)" BTD ENSG00000169814 Biotinidase P43251 3 15601341-15722311 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 97.0" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052275 Uncertain "Secreted to blood" Enzyme NA NA 2800000000 "Cluster 41: Basophils - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" "HPA052275: AB_2681782" "unprognostic (6.04e-2)" "unprognostic (2.42e-1)" "unprognostic (9.37e-3)" "unprognostic (5.84e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-2)" "unprognostic (6.37e-3)" "unprognostic (4.26e-2)" "unprognostic (3.29e-2)" "unprognostic (1.23e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "prognostic favorable (2.60e-9)" "unprognostic (2.44e-2)" "unprognostic (4.90e-2)" "unprognostic (1.67e-3)" "unprognostic (3.73e-2)" BTN1A1 "BT, BTN, BTN1" ENSG00000124557 "Butyrophilin subfamily 1 member A1" Q13410 6 26500303-26510425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 39 "breast: 31.0" "Cell type enriched" "Detected in some" 52 "Breast glandular cells: 108.0" "Cancer enhanced" "Detected in single" "breast cancer: 0.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.2;naive B-cell: 1.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011126, CAB037340" Supported "Intracellular and membrane" "No annotated function" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 73: Breast - Lactation" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 17: Breast glandular cells - Lactation" 1 "CAB037340: , HPA011126: AB_1845491" "unprognostic (4.07e-2)" "unprognostic (1.40e-1)" "unprognostic (1.90e-2)" "unprognostic (1.67e-1)" "unprognostic (2.32e-1)" "unprognostic (1.77e-2)" "unprognostic (5.50e-2)" "unprognostic (1.04e-1)" "unprognostic (3.24e-3)" "unprognostic (2.85e-1)" "unprognostic (1.88e-1)" "unprognostic (5.35e-10)" "unprognostic (4.62e-2)" "unprognostic (1.38e-1)" "unprognostic (4.14e-2)" "unprognostic (5.31e-4)" C10orf95 FLJ14280 ENSG00000120055 "Chromosome 10 open reading frame 95" 10 102449837-102451543 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 9.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 35.4;Oocytes: 29.4;Rod photoreceptor cells: 15.2;Syncytiotrophoblasts: 36.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in single" "Secreted - unknown location" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 39: Retina & Testis - Cilium" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" "unprognostic (2.31e-1)" "unprognostic (7.76e-3)" "unprognostic (3.19e-1)" "unprognostic (5.62e-3)" "unprognostic (4.02e-1)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (5.98e-2)" "unprognostic (1.50e-2)" "unprognostic (1.01e-1)" "unprognostic (4.42e-2)" "unprognostic (2.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (2.14e-1)" "unprognostic (1.22e-2)" "unprognostic (4.80e-3)" C12orf73 "BRAWNIN, DKFZp547P055, FLJ13975" ENSG00000204954 "Chromosome 12 open reading frame 73" Q69YU5 12 103940763-103965708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.0" "Cell type enhanced" "Detected in all" "Early spermatids: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038883 Uncertain Approved "Plasma membrane,Centrosome,Mitochondria" "Intracellular and membrane" "No annotated function" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 21: Early spermatids - Spermatogenesis" "Centrosome, Mitochondria" "Plasma membrane" "HPA038883: AB_10794735" "unprognostic (9.24e-2)" "unprognostic (3.26e-3)" "unprognostic (3.66e-3)" "unprognostic (7.20e-2)" "unprognostic (3.28e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.98e-4)" "unprognostic (8.96e-2)" "unprognostic (1.86e-2)" "unprognostic (3.79e-2)" "unprognostic (3.03e-3)" "unprognostic (2.07e-1)" "unprognostic (1.33e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (6.27e-2)" "prognostic favorable (1.61e-4)" C14orf93 "FLJ12154, RTFC" ENSG00000100802 "Chromosome 14 open reading frame 93" Q9H972 14 22985894-23010166 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002569 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" "No annotated function" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 18: Non-specific - Ribosome" "Cluster 46: Brainstem - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 "Nucleoplasm, Plasma membrane" "HPA002569: AB_1078334" "prognostic favorable (5.05e-4)" "unprognostic (1.31e-2)" "unprognostic (2.97e-2)" "unprognostic (2.23e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (4.86e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (2.14e-1)" "unprognostic (7.11e-2)" C15orf61 LOC145853 ENSG00000189227 "Chromosome 15 open reading frame 61" A6NNL5 15 67521131-67530146 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 22.9" "Cell type enhanced" "Detected in all" "Early spermatids: 302.3;Oocytes: 359.5;Spermatocytes: 215.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062820 Approved Nucleoli,Vesicles,Cytosol "Secreted - unknown location" "No annotated function" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 3: Non-specific - Unknown function" "Cluster 15: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "Nucleoli, Vesicles" Cytosol "HPA062820: AB_2684874" "unprognostic (1.35e-1)" "unprognostic (9.42e-3)" "unprognostic (2.11e-1)" "unprognostic (5.41e-2)" "unprognostic (2.40e-1)" "unprognostic (2.49e-1)" "unprognostic (1.49e-1)" "unprognostic (3.87e-3)" "unprognostic (8.95e-2)" "unprognostic (4.01e-2)" "unprognostic (1.04e-2)" "unprognostic (8.45e-2)" "prognostic favorable (5.31e-5)" "unprognostic (2.42e-2)" "unprognostic (9.78e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" C16orf89 MGC45438 ENSG00000153446 "Chromosome 16 open reading frame 89" Q6UX73 16 5044122-5066110 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.9;thyroid gland: 221.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 268.4;Club cells: 65.2;Distal tubular cells: 76.8;Fibroblasts: 33.6" "Group enriched" "Detected in many" 14 "lung cancer: 64.7;thyroid cancer: 145.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "thyroid cancer: 14.2" "Colon - Fibroblasts, Lung - Alveolar cells type 2, Prostate - Fibroblasts, Stomach - Chief cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013613, HPA016934" Enhanced "Secreted to blood" "No annotated function" NA NA 1400000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 72: Alveolar cells - Lung function" "HPA013613: AB_1845584, HPA016934: AB_2732417" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.97e-1)" "unprognostic (6.29e-2)" "unprognostic (3.79e-2)" "unprognostic (1.48e-1)" "unprognostic (2.67e-2)" "unprognostic (1.01e-2)" "unprognostic (9.23e-2)" "unprognostic (2.65e-1)" "unprognostic (6.39e-2)" "unprognostic (3.25e-2)" "unprognostic (6.64e-3)" "unprognostic (3.53e-2)" "unprognostic (1.25e-1)" "unprognostic (5.54e-2)" "unprognostic (8.48e-3)" C17orf67 ENSG00000214226 "Chromosome 17 open reading frame 67" Q0P5P2 17 56791913-56838773 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 35.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.1" "Region enhanced" "Detected in many" "spinal cord: 29.1" HPA043479 Approved "Secreted to blood" "No annotated function" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 2 "HPA043479: AB_10964083" "unprognostic (2.78e-2)" "unprognostic (5.24e-2)" "unprognostic (1.83e-1)" "unprognostic (3.54e-3)" "unprognostic (1.69e-3)" "unprognostic (1.59e-2)" "unprognostic (2.10e-2)" "unprognostic (2.47e-1)" "unprognostic (4.63e-2)" "unprognostic (2.82e-3)" "unprognostic (9.64e-2)" "unprognostic (2.99e-2)" "unprognostic (1.68e-5)" "unprognostic (2.49e-1)" "unprognostic (3.27e-1)" "unprognostic (2.20e-2)" "unprognostic (1.43e-3)" C17orf99 "GLPG464, UNQ464" ENSG00000187997 "Chromosome 17 open reading frame 99" Q6UX52 17 78146385-78166297 "Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "bone marrow: 8.6" "Group enriched" "Detected in some" 7 "Erythroid cells: 20.7;Oocytes: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 1.1;lymphoma: 2.6" "Not detected" "Not detected" HPA029655 Uncertain "Secreted to blood" Cytokine NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 1: Erythroid cells - Oxygen transport" "HPA029655: AB_10601691" "unprognostic (3.55e-5)" "unprognostic (1.87e-2)" "unprognostic (2.06e-1)" "unprognostic (1.22e-1)" "unprognostic (1.88e-1)" "unprognostic (1.45e-3)" "unprognostic (1.47e-3)" "unprognostic (2.39e-1)" "unprognostic (3.86e-1)" "unprognostic (9.77e-2)" "unprognostic (2.05e-2)" "unprognostic (5.13e-2)" "unprognostic (1.38e-4)" "unprognostic (6.58e-2)" "unprognostic (4.72e-2)" "unprognostic (2.66e-1)" "unprognostic (5.78e-3)" C18orf54 "LAS2, MGC33382" ENSG00000166845 "Chromosome 18 open reading frame 54" Q8IYD9 18 54357906-54385218 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 16.8" "Cell type enhanced" "Detected in many" "Early spermatids: 123.2;Extravillous trophoblasts: 26.6;Late spermatids: 32.9;Oligodendrocytes: 21.4;Spermatocytes: 35.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040704 Approved Nucleoplasm "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Testis - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 21: Early spermatids - Spermatogenesis" 7 Nucleoplasm "HPA040704: AB_10959454" "unprognostic (2.96e-1)" "unprognostic (5.58e-2)" "unprognostic (5.29e-2)" "unprognostic (8.63e-3)" "unprognostic (2.40e-1)" "unprognostic (1.05e-1)" "unprognostic (5.60e-6)" "unprognostic (1.11e-2)" "unprognostic (7.85e-3)" "unprognostic (2.55e-2)" "unprognostic (5.91e-3)" "unprognostic (1.13e-2)" "unprognostic (3.06e-5)" "unprognostic (2.29e-1)" "unprognostic (4.21e-1)" "unprognostic (1.28e-2)" "unprognostic (7.05e-2)" C19orf47 FLJ36888 ENSG00000160392 "Chromosome 19 open reading frame 47" Q8N9M1 19 40319536-40348527 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 87.1;skeletal muscle: 251.0;tongue: 132.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.6;Late spermatids: 25.8;Skeletal myocytes: 45.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 29.3" "Lineage enriched" "Detected in all" 10 "granulocytes: 29.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041843, HPA046309" Enhanced Enhanced Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 Nucleoplasm "HPA041843: AB_10959886, HPA046309: AB_10960266" "prognostic favorable (6.50e-4)" "unprognostic (1.35e-3)" "unprognostic (1.80e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (2.75e-1)" "unprognostic (4.73e-2)" "prognostic unfavorable (1.41e-4)" "unprognostic (2.26e-1)" "unprognostic (1.59e-1)" "unprognostic (1.63e-1)" "unprognostic (1.47e-2)" "unprognostic (3.25e-2)" "unprognostic (6.23e-2)" "unprognostic (1.62e-2)" "unprognostic (5.28e-2)" "unprognostic (2.77e-1)" "unprognostic (3.28e-2)" C1orf198 "DKFZp667D152, FLJ14525, FLJ16283, FLJ38847, MGC10710" ENSG00000119280 "Chromosome 1 open reading frame 198" Q9H425 1 230837119-230869589 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 138.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 115.2;Melanocytes: 85.9;Schwann cells: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 13.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 13.1" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004798 Approved Supported Cytosol "Intracellular and membrane" "No annotated function" NA NA 80000 "Cluster 14: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" Cytosol "HPA004798: AB_1848722" "unprognostic (7.44e-2)" "unprognostic (1.89e-1)" "unprognostic (1.17e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-2)" "unprognostic (2.46e-1)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (2.32e-1)" "unprognostic (3.75e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (4.50e-5)" "unprognostic (3.53e-2)" "unprognostic (4.95e-2)" "unprognostic (1.38e-1)" "unprognostic (3.77e-2)" C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 103.8;B-cells: 97.8;Kupffer cells: 106.8;Langerhans cells: 172.2;Peritubular cells: 102.8;Schwann cells: 464.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.8" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.8" "Cancer enhanced" "Detected in all" "Rhabdoid: 36.3" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" "No annotated function" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" "Plasma membrane" "HPA026518: AB_1845647, HPA043874: AB_2732511" "unprognostic (4.64e-3)" "unprognostic (6.81e-3)" "unprognostic (4.01e-3)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.16e-2)" "unprognostic (8.06e-2)" "unprognostic (1.33e-2)" "unprognostic (4.48e-2)" C1orf56 "FLJ20519, MENT" ENSG00000143443 "Chromosome 1 open reading frame 56" Q9BUN1 1 151047751-151051986 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 74.4" "Cell type enhanced" "Detected in all" "Early spermatids: 548.8;Langerhans cells: 291.7;NK-cells: 242.7;Spermatocytes: 258.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037429, HPA037430" Enhanced "Secreted to blood" "No annotated function" NA NA 87000000 "Cluster 32: Basophils - Transcription" "Cluster 44: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 3 "HPA037429: AB_10671755, HPA037430: AB_2675473" "unprognostic (7.60e-2)" "unprognostic (8.26e-2)" "unprognostic (1.09e-2)" "unprognostic (3.83e-1)" "unprognostic (4.31e-2)" "unprognostic (2.83e-2)" "unprognostic (1.11e-2)" "unprognostic (3.81e-3)" "unprognostic (1.59e-2)" "unprognostic (2.70e-3)" "unprognostic (3.28e-3)" "unprognostic (5.29e-2)" "unprognostic (3.61e-2)" "unprognostic (3.61e-2)" "unprognostic (6.16e-2)" "unprognostic (2.26e-1)" "unprognostic (4.79e-2)" C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22635077-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 621.7;lymphoid tissue: 1066.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 1545.9;Kupffer cells: 3931.0;Macrophages: 1776.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 38 "intermediate monocyte: 227.9;non-classical monocyte: 184.6" "Lineage enriched" "Detected in many" 59 "monocytes: 227.9" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" "Complement pathway" NA NA 2700000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 58: Macrophages - Innate immune response" 3 "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 973.1" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1340.6;Kupffer cells: 3907.0;Macrophages: 1814.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 142.5;non-classical monocyte: 103.0" "Lineage enriched" "Detected in many" 83 "monocytes: 142.5" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" "Complement pathway" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" C1QBP "gC1Q-R, gC1qR, HABP1, p32, SF2p32" ENSG00000108561 "Complement C1q binding protein" Q07021 17 5432777-5448830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Apoptosis, Complement pathway, Host-virus interaction, Immunity, Innate immunity, mRNA processing, mRNA splicing, Ribosome biogenesis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026483 Supported Approved "Plasma membrane,Mitochondria" "Secreted to blood" "Complement pathway" NA NA 410000 "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 16 "Plasma membrane" Mitochondria "HPA026483: AB_1847108" "unprognostic (2.18e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (6.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.76e-2)" "unprognostic (7.47e-2)" "unprognostic (4.62e-2)" "unprognostic (2.40e-3)" "unprognostic (6.03e-2)" "unprognostic (4.60e-3)" "unprognostic (3.08e-2)" "unprognostic (7.80e-3)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-1)" "unprognostic (3.97e-1)" C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643014-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 923.4" "Group enriched" "Detected in many" 5 "Hofbauer cells: 1156.0;Kupffer cells: 1255.6;Macrophages: 969.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "intermediate monocyte: 56.5" "Lineage enriched" "Detected in single" 559 "monocytes: 56.5" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" "Complement pathway" NA NA 513000000 2100000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 3 "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" C1QL1 "C1QRF, C1QTNF14, CRF, CTRP14" ENSG00000131094 "Complement C1q like 1" O75973 17 44959693-44968303 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.7;kidney: 20.4" "Group enriched" "Detected in some" 6 "Horizontal cells: 288.3;Mesothelial cells: 112.1;Oligodendrocyte precursor cells: 79.2" "Cancer enriched" "Detected in all" 7 "glioma: 116.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 91.1" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Liver - Cholangiocyte, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071349 Approved Vesicles,Cytosol "Secreted in brain" "Complement pathway" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Vesicles Cytosol "HPA071349: " "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (3.63e-3)" "unprognostic (3.15e-2)" "unprognostic (2.05e-2)" "unprognostic (7.65e-2)" "unprognostic (3.40e-3)" "unprognostic (2.34e-1)" "unprognostic (6.64e-3)" "unprognostic (1.49e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.31e-8)" "unprognostic (2.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.61e-2)" "unprognostic (3.04e-1)" C1QL2 "C1QTNF10, CTRP10" ENSG00000144119 "Complement C1q like 2" Q7Z5L3 2 119156243-119158751 "Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 24.5" "Group enriched" "Detected in some" 13 "Horizontal cells: 122.7;Oligodendrocyte precursor cells: 34.9" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Bone cancer: 1.5" "Region enhanced" "Detected in many" "hippocampal formation: 22.7" "Low region specificity" "Detected in many" "HPA057934, HPA071349" Uncertain Approved Vesicles,Cytosol "Secreted in brain" "Complement pathway" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Vesicles Cytosol "HPA057934: AB_2683558, HPA071349: " "unprognostic (6.95e-2)" "unprognostic (9.74e-2)" "unprognostic (4.48e-3)" "unprognostic (1.08e-1)" "unprognostic (9.91e-4)" "unprognostic (2.60e-5)" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" C1QL3 "C1ql, C1QTNF13, CTRP13, K100" ENSG00000165985 "Complement C1q like 3" Q5VWW1 10 16513734-16521879 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 26.9;retina: 7.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.6;Horizontal cells: 1.3;Rod photoreceptor cells: 4.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 5.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 95.8;cerebral cortex: 76.5;hippocampal formation: 68.7" HPA071349 Approved Vesicles,Cytosol "Secreted in brain" "Complement pathway" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Neurons - Neuronal signaling" Vesicles Cytosol "HPA071349: " "unprognostic (7.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (8.19e-3)" "unprognostic (6.31e-2)" "unprognostic (5.12e-2)" "unprognostic (3.89e-2)" "unprognostic (2.76e-2)" "unprognostic (2.00e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "prognostic favorable (6.29e-5)" "unprognostic (3.27e-2)" "unprognostic (1.66e-1)" "unprognostic (8.59e-2)" "unprognostic (6.12e-2)" C1QL4 "C1QTNF11, CTRP11" ENSG00000186897 "Complement C1q like 4" Q86Z23 12 49332409-49337188 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.1" "Cell type enriched" "Detected in some" 4 "Late spermatids: 92.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "pons: 16.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 19.0" "Adipose visceral - Mesothelial cells, Testis - Late spermatids" "Region enhanced" "Detected in some" "midbrain: 6.2" "Region enhanced" "Detected in many" "pons: 11.2" HPA071349 Approved Vesicles,Cytosol "Secreted in brain" "Complement pathway" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 36: Late spermatids - Unknown function" 16 Vesicles Cytosol "HPA071349: " "unprognostic (1.97e-2)" "unprognostic (2.77e-2)" "unprognostic (4.87e-2)" "unprognostic (7.37e-2)" "unprognostic (4.48e-1)" "unprognostic (1.86e-2)" "unprognostic (2.49e-3)" "unprognostic (8.64e-3)" "unprognostic (2.89e-1)" "unprognostic (5.11e-3)" "unprognostic (7.62e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (9.73e-2)" "unprognostic (2.85e-2)" "unprognostic (9.40e-2)" "unprognostic (3.72e-2)" C1QTNF1 "CTRP1, FLJ90694, GIP, ZSIG37" ENSG00000173918 "C1q and TNF related 1" Q9BXJ1 17 79022814-79049788 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 207.3;heart muscle: 308.6" "Cell type enhanced" "Detected in many" "Adipocytes: 37.4;Fibroblasts: 36.5;Mesothelial cells: 48.2;Sertoli cells: 35.4;Smooth muscle cells: 127.7;Syncytiotrophoblasts: 45.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025429, HPA051101" Uncertain Approved Nucleoplasm,Cytosol "Secreted to blood" "Complement pathway" NA NA 314000000 40000 "Cluster 30: Heart muscle - Heart development" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 3 "Nucleoplasm, Cytosol" "CAB025429: , HPA051101: AB_2681343" "unprognostic (2.58e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (1.20e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" "unprognostic (7.11e-2)" "unprognostic (3.18e-1)" "unprognostic (1.07e-2)" "unprognostic (1.23e-2)" "unprognostic (7.48e-2)" "unprognostic (9.81e-3)" "unprognostic (5.83e-2)" "prognostic unfavorable (9.09e-9)" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (1.95e-2)" C1QTNF12 "ADIPOLIN, C1QDC2, CTRP12, FAM132A, MGC105127" ENSG00000184163 "C1q and TNF related 12" Q5T7M4 1 1242446-1246722 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.6;skin 1: 6.4" "Group enriched" "Detected in many" 4 "Distal enterocytes: 146.5;Proximal enterocytes: 213.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.5" "Adipose visceral - Endothelial cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024107 Uncertain Approved Vesicles "Secreted to blood" "Complement pathway" NA NA 38200000 "Cluster 45: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA024107: AB_2101207" "unprognostic (1.10e-2)" "unprognostic (5.68e-3)" "unprognostic (3.45e-1)" "unprognostic (1.24e-2)" "unprognostic (6.60e-3)" "unprognostic (2.43e-1)" "unprognostic (2.67e-3)" "unprognostic (1.01e-2)" "unprognostic (2.58e-1)" "unprognostic (1.05e-2)" "unprognostic (8.02e-3)" "unprognostic (1.10e-2)" "unprognostic (9.68e-3)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 17.2;Leydig cells: 21.6;Lymphatic endothelial cells: 8.1;Peritubular cells: 30.3;Smooth muscle cells: 24.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.2" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.2" "Cancer enhanced" "Detected in some" "Sarcoma: 7.0" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" "Complement pathway" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 53: Fibroblasts - ECM organization" 17 "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" C1QTNF3 "2310005P21Rik, Corcs, Cors, Cors-26, CTRP3" ENSG00000082196 "C1q and TNF related 3" Q9BXJ4 5 34017858-34043213 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.1;salivary gland: 50.7" "Group enriched" "Detected in many" 4 "Early spermatids: 91.3;Late spermatids: 332.0;Muller glia cells: 197.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 23.9;skin cancer: 12.0" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA064996, HPA066011" Uncertain Approved "Golgi apparatus" "Secreted to blood" "Complement pathway" NA NA 44100000 24000000 "Cluster 39: Retina & Testis - Cilium" "Cluster 25: Non-specific - Transcription" "Cluster 20: Myeloma - Immune response" "Cluster 53: Fibroblasts - ECM organization" 1 "Golgi apparatus" "HPA064996: AB_2685399, HPA066011: AB_2685597" "unprognostic (7.71e-2)" "unprognostic (2.81e-3)" "unprognostic (5.83e-2)" "unprognostic (6.58e-2)" "unprognostic (3.14e-2)" "unprognostic (1.98e-1)" "unprognostic (2.21e-1)" "unprognostic (2.09e-3)" "unprognostic (5.18e-2)" "unprognostic (1.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (4.89e-3)" "unprognostic (1.80e-1)" "unprognostic (9.38e-3)" "unprognostic (2.35e-1)" C1QTNF4 "CTRP4, ZACRP4" ENSG00000172247 "C1q and TNF related 4" Q9BXJ3 11 47589667-47594411 "Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 117.6" "Cell type enhanced" "Detected in many" "Granulosa cells: 66.3;Late spermatids: 50.6;Leydig cells: 44.9;Muller glia cells: 43.4;Ovarian stromal cells: 98.2;Peritubular cells: 41.4;Spermatogonia: 51.0" "Group enriched" "Detected in some" 4 "glioma: 1.7;ovarian cancer: 2.5;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 2.5" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041032 Approved Uncertain "Golgi apparatus,Vesicles" "Secreted in brain" Cytokine NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 6: Ovarian stromal cells - Transcription" 3 "Golgi apparatus, Vesicles" "HPA041032: AB_10671170" "unprognostic (1.84e-3)" "unprognostic (1.58e-1)" "unprognostic (8.98e-4)" "unprognostic (8.19e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-3)" "unprognostic (6.78e-2)" "unprognostic (6.11e-2)" "unprognostic (6.35e-2)" "unprognostic (4.00e-1)" "unprognostic (4.91e-4)" "unprognostic (1.22e-1)" "unprognostic (8.22e-6)" "unprognostic (6.02e-3)" "unprognostic (1.00e-1)" "unprognostic (2.80e-2)" "unprognostic (6.28e-2)" C1QTNF5 "CTRP5, DKFZp586B0621, LORD" ENSG00000223953 "C1q and TNF related 5" Q9BXJ0 11 119338942-119340940 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "choroid plexus: 571.0" "Cell type enhanced" "Detected in some" "Endothelial cells: 1.4;Fibroblasts: 2.9;Gastric mucus-secreting cells: 1.8;Smooth muscle cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 6.7;Sarcoma: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025607, HPA038604" Uncertain "Secreted to blood" "Complement pathway" NA NA 219000000 1500000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 49: Non-specific - Transcription" 5 "CAB025607: , HPA038604: AB_2676110" C1QTNF6 "CTRP6, ZACRP6" ENSG00000133466 "C1q and TNF related 6" Q9BXI9 22 37180166-37199385 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 30.7;placenta: 28.6" "Cell type enriched" "Detected in many" 15 "Extravillous trophoblasts: 477.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002042 Enhanced Approved Nucleoplasm "Secreted to blood" "Complement pathway" No No 354000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" 2 Nucleoplasm "HPA002042: AB_1078342" "unprognostic (9.65e-2)" "unprognostic (1.21e-2)" "unprognostic (2.32e-1)" "unprognostic (2.23e-3)" "unprognostic (1.25e-3)" "unprognostic (3.01e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.60e-6)" "unprognostic (6.96e-2)" "unprognostic (5.11e-2)" "unprognostic (2.61e-2)" "unprognostic (1.72e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.61e-2)" "unprognostic (5.36e-2)" "unprognostic (1.08e-3)" "unprognostic (1.52e-2)" C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 19.4;Fibroblasts: 28.8;Leydig cells: 20.9;Ovarian stromal cells: 18.9;Peritubular cells: 33.5;Smooth muscle cells: 14.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" "Complement pathway" NA NA 238000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" C1QTNF8 "CTRP8, UNQ5829" ENSG00000184471 "C1q and TNF related 8" P60827 16 1088226-1096244 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 1.7;pituitary gland: 1.7" "Cell type enhanced" "Detected in single" "Ciliated cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" HPA056438 Uncertain "Secreted - unknown location" "Complement pathway" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 42: Ciliated cells - Cilium assembly" "HPA056438: AB_2683134" "unprognostic (8.65e-2)" "unprognostic (2.56e-2)" "unprognostic (5.46e-2)" C1QTNF9 "AQL1, C1QTNF9A, CTRP9, MGC48915" ENSG00000240654 "C1q and TNF related 9" P0C862 13 24307166-24322535 "Predicted secreted proteins, Transporters" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 8.1" "Group enriched" "Detected in some" 7 "Adipocytes: 33.7;Endothelial cells: 12.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056632 Uncertain "Secreted to blood" "Complement pathway" NA NA 210000000 "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "HPA056632: AB_2683197" "unprognostic (1.18e-2)" "unprognostic (3.22e-2)" "unprognostic (2.44e-2)" "unprognostic (3.14e-3)" "unprognostic (9.22e-2)" "unprognostic (1.48e-1)" "unprognostic (1.96e-2)" "unprognostic (3.63e-2)" "unprognostic (1.03e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-2)" "unprognostic (4.16e-2)" "unprognostic (3.29e-4)" "unprognostic (1.38e-2)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (2.22e-1)" C1QTNF9B CTRP9B ENSG00000205863 "C1q and TNF related 9B" B2RNN3 13 23891099-23897502 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.4;testis: 8.6" "Cell type enhanced" "Detected in some" "Adipocytes: 3.6;Early spermatids: 1.9;Late spermatids: 2.1" "Cancer enhanced" "Detected in single" "prostate cancer: 0.8" "Region enriched" "Detected in many" 4 "hippocampal formation: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA056632 Uncertain "Secreted - unknown location" "Complement pathway" NA NA "Cluster 13: Skin - Cornification" "Cluster 29: Forebrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "HPA056632: AB_2683197" "unprognostic (3.43e-1)" "unprognostic (3.42e-1)" "unprognostic (2.18e-2)" "unprognostic (9.51e-2)" "unprognostic (2.18e-1)" "unprognostic (4.10e-2)" "unprognostic (2.43e-1)" "unprognostic (3.32e-3)" "unprognostic (1.52e-2)" "unprognostic (7.26e-2)" "unprognostic (3.01e-3)" "unprognostic (7.04e-2)" "unprognostic (5.56e-3)" "unprognostic (3.89e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (1.34e-1)" C1RL "C1r-LP, C1RL1" ENSG00000139178 "Complement C1r subcomponent like" Q9NZP8 12 7089587-7109238 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011338, CAB026172" Supported "Secreted to blood" "Complement pathway" NA NA 5500000000 15000000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 53: Fibroblasts - ECM organization" "CAB026172: , HPA011338: AB_1847111" "prognostic favorable (7.92e-4)" "unprognostic (7.76e-2)" "unprognostic (3.91e-3)" "unprognostic (5.25e-3)" "unprognostic (2.92e-3)" "unprognostic (9.60e-2)" "unprognostic (2.75e-3)" "unprognostic (7.76e-2)" "unprognostic (1.22e-1)" "unprognostic (4.34e-1)" "unprognostic (9.58e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.75e-1)" "unprognostic (5.74e-2)" "unprognostic (2.52e-1)" "unprognostic (2.26e-3)" C1S ENSG00000182326 "Complement C1s" P09871 12 6988259-7071032 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 2762.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 717.8;Hepatocytes: 2248.0;Leydig cells: 1204.3;Mesothelial cells: 578.3;Ovarian stromal cells: 401.7;Peritubular cells: 631.2" "Cancer enhanced" "Detected in all" "liver cancer: 276.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB016722, HPA018852" Supported Approved Nucleoplasm,Cytosol "Secreted to blood" "Complement pathway" NA NA 93000000000 14000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 Nucleoplasm Cytosol "CAB016722: , HPA018852: AB_1847112" "unprognostic (2.72e-3)" "unprognostic (7.31e-2)" "unprognostic (9.37e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-2)" "unprognostic (9.63e-2)" "prognostic favorable (7.73e-4)" "unprognostic (6.38e-2)" "unprognostic (1.16e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (7.44e-15)" "unprognostic (2.02e-2)" "unprognostic (5.68e-3)" "unprognostic (1.19e-2)" "unprognostic (5.39e-2)" C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945673 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 466.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 194.1;Hepatocytes: 323.8;Hofbauer cells: 241.9;Kupffer cells: 141.5" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.7;non-classical monocyte: 26.1" "Lineage enriched" "Detected in single" 33 "monocytes: 26.1" "Group enriched" "Detected in many" 4 "liver cancer: 11.4;Myeloma: 14.9;thyroid cancer: 5.1" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB016775 Supported "Secreted to blood" "Complement pathway" NA NA 34000000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 62: Hepatocytes - Metabolism" 6 "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" C21orf62 "B37, C21orf120, PRED81" ENSG00000205929 "Chromosome 21 open reading frame 62" Q9NYP8 21 32790673-32813743 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 22.6;epididymis: 8.2;ovary: 8.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 38.2;Mesothelial cells: 31.6;Ovarian stromal cells: 17.9" "Cancer enriched" "Detected in some" 6 "glioma: 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016899 Enhanced "Secreted - unknown location" "No annotated function" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Ovarian stromal cells - Transcription" "HPA016899: AB_1845704" "unprognostic (1.31e-1)" "unprognostic (3.84e-2)" "unprognostic (1.23e-1)" "unprognostic (4.37e-3)" "unprognostic (9.56e-2)" "unprognostic (3.05e-3)" "unprognostic (2.95e-2)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.85e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.59e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" C22orf15 "FLJ36561, N27C7-3" ENSG00000169314 "Chromosome 22 open reading frame 15" Q8WYQ4 22 23762990-23765863 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "fallopian tube: 17.7" "Group enriched" "Detected in some" 7 "Ciliated cells: 109.4;Ionocytes: 29.1" "Cancer enriched" "Detected in single" 4 "endometrial cancer: 1.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Bone cancer: 1.1" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted in female reproductive system" "No annotated function" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 59: Fallopian tube - Tissue development" "Cluster 46: Brainstem - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" "unprognostic (2.37e-2)" "unprognostic (3.28e-3)" "unprognostic (1.28e-1)" "prognostic favorable (8.53e-5)" "unprognostic (1.86e-2)" "unprognostic (2.07e-2)" "unprognostic (4.38e-2)" "unprognostic (6.14e-2)" "unprognostic (3.60e-2)" "unprognostic (7.70e-2)" "unprognostic (4.58e-2)" "unprognostic (2.60e-1)" "unprognostic (9.79e-2)" "unprognostic (2.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.28e-2)" "unprognostic (3.08e-3)" C2CD2 "C21orf25, C21orf258, DKFZP586F0422, TMEM24L" ENSG00000157617 "C2 calcium dependent domain containing 2" Q9Y426 21 41885112-41954018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 122.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 50.4;Cone photoreceptor cells: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030922, HPA030924" Enhanced Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 25: Bipolar cells - Visual perception" Nucleoplasm "HPA030922: AB_2673660, HPA030924: AB_10669873" "unprognostic (3.02e-3)" "unprognostic (3.69e-2)" "unprognostic (2.21e-2)" "unprognostic (9.63e-2)" "unprognostic (3.15e-3)" "unprognostic (2.93e-2)" "unprognostic (2.39e-2)" "unprognostic (3.44e-2)" "unprognostic (3.00e-2)" "unprognostic (4.39e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.68e-5)" "unprognostic (1.99e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-2)" "unprognostic (1.48e-1)" C2orf66 UNQ6411 ENSG00000187944 "Chromosome 2 open reading frame 66" 2 196804417-196809355 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adipose tissue: 2.7;adrenal gland: 3.8;pituitary gland: 3.6" "Cell type enriched" "Detected in some" 6 "Early spermatids: 50.7" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020869 Uncertain Uncertain Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 21: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA020869: AB_1851545" "unprognostic (1.19e-1)" "unprognostic (4.85e-2)" "unprognostic (6.95e-2)" "unprognostic (1.19e-1)" "unprognostic (3.48e-2)" "unprognostic (1.61e-2)" "unprognostic (6.80e-3)" "unprognostic (3.05e-2)" "unprognostic (1.95e-1)" "unprognostic (4.10e-3)" "unprognostic (4.54e-4)" "unprognostic (1.98e-1)" "unprognostic (1.75e-5)" "unprognostic (1.84e-1)" "unprognostic (2.30e-1)" "unprognostic (1.38e-2)" "unprognostic (1.86e-2)" C2orf69 FLJ38973 ENSG00000178074 "Chromosome 2 open reading frame 69" Q8N8R5 2 199911293-199955935 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 148.5;Late spermatids: 80.1;Spermatocytes: 118.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045225 Approved "Intracellular and membrane" Transport NA Yes "Cluster 24: Non-specific - Transcription" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA045225: AB_10960841" "unprognostic (6.94e-3)" "unprognostic (1.09e-1)" "unprognostic (7.17e-2)" "unprognostic (3.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (4.39e-3)" "unprognostic (1.92e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.33e-3)" "unprognostic (1.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.41e-3)" "unprognostic (8.87e-2)" "unprognostic (1.03e-2)" "unprognostic (5.86e-2)" C3 "ARMD9, C3a, C3b, CPAMD1" ENSG00000125730 "Complement C3" P01024 19 6677704-6730562 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Fatty acid metabolism, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Age-related macular degeneration, Disease variant, FDA approved drug targets, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "liver: 5250.9" "Cell type enhanced" "Detected in many" "Ductal cells: 657.6;Exocrine glandular cells: 845.2;Hepatocytes: 3158.4;Mesothelial cells: 2220.5" "Cancer enriched" "Detected in all" 5 "liver cancer: 1213.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "non-classical monocyte: 14.5" "Lineage enriched" "Detected in many" 5 "monocytes: 14.5" "Cancer enhanced" "Detected in many" "liver cancer: 255.0" "Liver - Hepatocytes, Lung - Fibroblast_2, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003563, CAB004209, HPA020432" Enhanced "Secreted to blood" "Complement pathway" NA NA 1260000000000 200000000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Hepatocytes - Metabolism" 9 "CAB004209: AB_627277, HPA003563: AB_1847117, HPA020432: AB_1847118" "unprognostic (3.26e-3)" "unprognostic (3.91e-1)" "unprognostic (3.92e-1)" "unprognostic (5.98e-3)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "prognostic favorable (8.11e-4)" "unprognostic (1.99e-1)" "unprognostic (9.26e-2)" "unprognostic (5.80e-2)" "unprognostic (8.12e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.63e-2)" "unprognostic (2.49e-2)" "unprognostic (6.03e-3)" "unprognostic (3.88e-1)" C3orf33 "AC3-33, FLJ31139" ENSG00000174928 "Chromosome 3 open reading frame 33" Q6P1S2 3 155762617-155806278 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Inhibitory neurons: 14.3;Oocytes: 14.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA037663 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA037663: AB_10672610" "unprognostic (1.18e-1)" "unprognostic (9.39e-3)" "unprognostic (1.48e-1)" "unprognostic (1.66e-3)" "unprognostic (1.31e-1)" "unprognostic (7.27e-2)" "unprognostic (6.31e-3)" "unprognostic (3.28e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic favorable (6.48e-7)" "unprognostic (3.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.24e-2)" "unprognostic (1.56e-1)" C4A "C4, C4A2, C4A3, C4A4, C4A6, C4B, C4S, CO4, CPAMD2, RG" ENSG00000244731 "Complement C4A (Rodgers blood group)" P0C0L4 6 31982057-32002681 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 112.2;liver: 328.2" "Group enriched" "Detected in some" 4 "Hepatocytes: 6.8;Mesothelial cells: 8.5" "Cancer enhanced" "Detected in many" "liver cancer: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 8.8;Myeloma: 6.7" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "CAB009811, CAB032603, HPA046356, HPA048287, HPA050103" Supported "Secreted to blood" "Complement pathway" NA NA 342000000 120000000000 "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 2 "CAB009811: AB_2066891, CAB032603: AB_2290613, HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (2.13e-1)" "unprognostic (3.02e-2)" "unprognostic (3.74e-2)" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (3.09e-2)" "unprognostic (2.48e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.20e-2)" "unprognostic (3.97e-2)" "unprognostic (8.63e-2)" C4B "C4B1, C4B3, C4F, CH, CO4, CPAMD3" ENSG00000224389 "Complement C4B (Chido blood group)" P0C0L5 6 32014795-32035418 "Blood group antigen proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Inflammatory response, Innate immunity" "Blood group antigen" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 214.6;liver: 375.4" "Group enriched" "Detected in some" 5 "Hepatocytes: 7.1;Mesothelial cells: 13.6" "Cancer enhanced" "Detected in many" "liver cancer: 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 6.7;Myeloma: 3.9" "Liver - Hepatocytes" "HPA046356, HPA048287, HPA050103" Approved "Secreted to blood" "Complement pathway" NA NA 120000000000 "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 1 "HPA046356: AB_2679635, HPA048287: AB_2680341, HPA050103: AB_2681016" "unprognostic (1.29e-1)" "unprognostic (2.99e-2)" "unprognostic (5.50e-3)" "unprognostic (1.30e-1)" "unprognostic (8.09e-2)" "unprognostic (6.24e-2)" "unprognostic (6.09e-2)" "unprognostic (1.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.12e-1)" "unprognostic (6.24e-2)" "unprognostic (6.86e-2)" "unprognostic (1.04e-1)" "unprognostic (3.12e-2)" "unprognostic (1.30e-1)" "unprognostic (3.99e-3)" "unprognostic (1.11e-2)" C4BPA C4BP ENSG00000123838 "Complement component 4 binding protein alpha" P04003 1 207104233-207144972 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 1860.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 321.7;Hepatocytes: 852.2" "Cancer enriched" "Detected in many" 7 "liver cancer: 434.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 137 "neutrophil: 29.6" "Lineage enriched" "Detected in single" 137 "granulocytes: 29.6" "Cancer enhanced" "Detected in some" "liver cancer: 7.4;lung cancer: 3.9" "Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.6" "HPA000926, HPA001578" Enhanced "Secreted to blood" "Complement pathway" NA NA 30800000000 28000000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Hepatocytes - Metabolism" "HPA000926: AB_1078355, HPA001578: AB_1078354" "unprognostic (3.85e-4)" "unprognostic (9.07e-2)" "unprognostic (2.06e-1)" "prognostic favorable (6.37e-5)" "unprognostic (3.58e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.24e-4)" "unprognostic (3.64e-2)" "unprognostic (1.94e-1)" "unprognostic (5.90e-4)" "unprognostic (4.47e-2)" "unprognostic (2.58e-1)" "unprognostic (5.51e-7)" "unprognostic (9.74e-2)" "unprognostic (2.52e-2)" "unprognostic (6.92e-2)" "unprognostic (2.66e-1)" C4BPB C4BP ENSG00000123843 "Complement component 4 binding protein beta" P20851 1 207088860-207099993 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "liver: 458.6" "Cell type enriched" "Detected in many" 12 "Hepatocytes: 654.1" "Cancer enriched" "Detected in many" 19 "liver cancer: 83.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Bile duct cancer: 39.5" "Adipose subcutaneous - Macrophages, Testis - Late spermatids" "Not detected" "Not detected" "HPA000925, HPA051620" Approved Uncertain "Golgi apparatus" "Secreted to blood" "Complement pathway" NA NA 265000000000 1100000000 "Cluster 30: Non-specific - DNA binding" "Cluster 31: Liver - Plasma proteins" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 43: Hepatocytes - Metabolism" "Golgi apparatus" "HPA000925: , HPA051620: AB_2681554" "unprognostic (1.73e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-1)" "unprognostic (2.07e-3)" "unprognostic (1.72e-1)" "unprognostic (2.54e-2)" "unprognostic (4.58e-3)" "unprognostic (9.49e-2)" "unprognostic (1.37e-1)" "unprognostic (4.25e-1)" "unprognostic (6.39e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (8.25e-2)" C4orf48 ENSG00000243449 "Chromosome 4 open reading frame 48" Q5BLP8 4 2041995-2043964 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 141.6;pituitary gland: 72.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 397.0;Granulosa cells: 528.9;Melanocytes: 506.8;Pancreatic endocrine cells: 395.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052447 Uncertain Approved Cytosol "Secreted to blood" "No annotated function" NA NA 190000 "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" Cytosol "HPA052447: AB_2681837" "unprognostic (7.96e-2)" "unprognostic (2.57e-3)" "unprognostic (2.08e-1)" "unprognostic (3.20e-2)" "unprognostic (4.01e-2)" "unprognostic (8.26e-2)" "unprognostic (4.85e-3)" "unprognostic (2.51e-3)" "unprognostic (2.28e-3)" "unprognostic (1.80e-1)" "unprognostic (1.95e-2)" "unprognostic (5.55e-2)" "unprognostic (3.42e-2)" "unprognostic (5.38e-3)" "unprognostic (2.68e-1)" "unprognostic (5.55e-2)" "unprognostic (3.17e-3)" C5 "C5a, C5b, CPAMD4" ENSG00000106804 "Complement C5" P01031 9 120932987-121075195 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Inflammatory response, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 30 "liver: 434.4" "Cell type enriched" "Detected in many" 14 "Hepatocytes: 435.9" "Cancer enriched" "Detected in many" 17 "liver cancer: 73.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "liver cancer: 21.1" "Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA029339 Supported "Secreted to blood" "Complement pathway" NA NA 113000000000 39000000000 "Cluster 83: Liver - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 17 "HPA029339: AB_10601125" "unprognostic (2.51e-1)" "unprognostic (5.88e-3)" "unprognostic (2.50e-3)" "unprognostic (1.57e-2)" "unprognostic (5.05e-2)" "unprognostic (9.52e-3)" "prognostic favorable (9.43e-4)" "unprognostic (1.83e-1)" "unprognostic (3.19e-2)" "unprognostic (1.55e-1)" "unprognostic (2.35e-2)" "unprognostic (4.41e-2)" "unprognostic (1.46e-5)" "unprognostic (5.91e-2)" "unprognostic (1.20e-1)" "unprognostic (3.67e-2)" "unprognostic (2.75e-1)" C5orf46 "AP-64, MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "salivary gland: 176.1;skin 1: 109.5" "Group enriched" "Detected in many" 8 "Early spermatids: 288.8;Late spermatids: 207.1;Mucus glandular cells: 101.8;Serous glandular cells: 247.4" "Cancer enhanced" "Detected in many" "renal cancer: 8.3" "Group enriched" "Detected in some" 7 "cerebellum: 4.8;choroid plexus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 61.6" "Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" "No annotated function" NA NA 54000 "Cluster 13: Skin - Cornification" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 75: Serous glandular cells - Salivary secretion" 11 "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.72e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.26e-4)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.69e-3)" "unprognostic (1.99e-2)" "unprognostic (3.08e-2)" "unprognostic (2.22e-1)" "unprognostic (4.96e-2)" "unprognostic (2.86e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.75e-9)" "unprognostic (6.48e-3)" "unprognostic (3.47e-2)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" C6 ENSG00000039537 "Complement C6" P13671 5 41142116-41261438 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 610.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 125.9;Ciliated cells: 63.9;Hepatocytes: 323.6;Late spermatids: 53.2;Leydig cells: 118.1" "Group enriched" "Detected in many" 7 "liver cancer: 49.0;pancreatic cancer: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.1" "Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA043823, CAB069427" Enhanced "Secreted to blood" "Complement pathway" NA NA 45000000000 9200000000 "Cluster 83: Liver - Metabolism" "Cluster 3: Choroid plexus - Cilium" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 62: Hepatocytes - Metabolism" 1 "CAB069427: AB_1614336, HPA043823: AB_10960262" "unprognostic (9.79e-2)" "unprognostic (1.96e-2)" "unprognostic (5.94e-3)" "unprognostic (3.02e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.12e-3)" "unprognostic (4.66e-2)" "unprognostic (3.72e-2)" "unprognostic (1.53e-1)" "unprognostic (2.34e-1)" "unprognostic (3.04e-3)" "prognostic favorable (4.31e-4)" "unprognostic (2.69e-4)" "unprognostic (1.61e-1)" "unprognostic (1.40e-2)" "unprognostic (3.51e-2)" C6orf120 bA160E12.4 ENSG00000185127 "Chromosome 6 open reading frame 120" Q7Z4R8 6 169702126-169706360 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 120.6;Late spermatids: 273.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039626 Uncertain "Secreted to blood" Other NA NA 620000 "Cluster 7: Non-specific - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 63: Late spermatids - Spermatogenesis" "HPA039626: AB_10673361" "unprognostic (2.98e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (3.43e-2)" "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" "unprognostic (4.30e-3)" "prognostic unfavorable (9.52e-5)" "unprognostic (1.78e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.56e-1)" "unprognostic (1.30e-1)" "unprognostic (1.63e-1)" "unprognostic (6.21e-3)" "unprognostic (2.88e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-3)" C6orf15 STG ENSG00000204542 "Chromosome 6 open reading frame 15" Q6UXA7 6 31111223-31112575 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 5.3;lymphoid tissue: 3.4;skin 1: 6.5" "Cell type enriched" "Detected in some" 8 "Breast glandular cells: 75.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 20.9;colorectal cancer: 26.9;Esophageal cancer: 22.8" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA001436 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 13: Skin - Cornification" "Cluster 32: Non-specific - Cell proliferation" "Cluster 17: Breast glandular cells - Lactation" 5 "HPA001436: AB_2243752" "unprognostic (2.73e-2)" "unprognostic (5.39e-2)" "unprognostic (1.46e-2)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.35e-1)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.72e-1)" "unprognostic (1.90e-1)" "unprognostic (1.34e-3)" C6orf58 LEG1 ENSG00000184530 "Chromosome 6 open reading frame 58" Q6P5S2 6 127519455-127591820 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 595.4;salivary gland: 2191.7" "Cell type enhanced" "Detected in some" "Club cells: 7.5;Early spermatids: 21.4;Gastric mucus-secreting cells: 46.6;Mucus glandular cells: 8.7" "Group enriched" "Detected in some" 6 "pancreatic cancer: 17.1;stomach cancer: 14.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 2.3;lymphoma: 3.3" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036263, HPA041449" Enhanced "Secreted to digestive system" "Developmental protein" NA NA 30000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 46: Gastric mucus-secreting cells - Digestion" 5 "HPA036263: AB_10673349, HPA041449: AB_2677486" "unprognostic (1.49e-1)" "unprognostic (8.55e-2)" "unprognostic (2.71e-1)" "unprognostic (5.69e-2)" "unprognostic (3.86e-2)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (3.26e-2)" "unprognostic (7.72e-3)" "unprognostic (1.69e-1)" "unprognostic (6.62e-4)" "unprognostic (2.10e-2)" "unprognostic (2.31e-1)" "unprognostic (1.53e-2)" "unprognostic (8.99e-3)" C7 ENSG00000112936 "Complement C7" P10643 5 40909492-41020216 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 884.6" "Group enriched" "Detected in many" 4 "Fibroblasts: 729.1;Leydig cells: 1107.4" "Cancer enriched" "Detected in all" 4 "pancreatic cancer: 73.8" "Region enhanced" "Detected in many" "choroid plexus: 33.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Neuroblastoma: 50.9" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 18.6" HPA001465 Approved "Secreted to blood" "Complement pathway" NA NA 48000000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "HPA001465: AB_1078554" "unprognostic (5.01e-2)" "unprognostic (3.74e-2)" "unprognostic (7.40e-2)" "unprognostic (4.68e-3)" "unprognostic (5.35e-2)" "unprognostic (1.43e-3)" "prognostic favorable (5.89e-4)" "unprognostic (6.67e-2)" "unprognostic (3.45e-1)" "unprognostic (2.21e-2)" "unprognostic (1.33e-1)" "unprognostic (1.93e-3)" "unprognostic (2.24e-2)" "unprognostic (6.10e-3)" "unprognostic (1.12e-1)" "unprognostic (2.14e-1)" "unprognostic (2.06e-3)" C8A ENSG00000157131 "Complement C8 alpha chain" P07357 1 56854768-56918223 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 279 "liver: 481.7" "Cell type enriched" "Detected in some" 14 "Hepatocytes: 257.7" "Cancer enriched" "Detected in single" 279 "liver cancer: 85.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" "Complement pathway" NA NA 6400000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 6 "unprognostic (3.73e-3)" "unprognostic (2.44e-1)" "unprognostic (1.28e-1)" "unprognostic (6.40e-2)" "unprognostic (9.82e-2)" C8B ENSG00000021852 "Complement C8 beta chain" P07358 1 56929207-56974383 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 127 "liver: 630.0" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 247.1" "Cancer enriched" "Detected in some" 181 "liver cancer: 107.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 2.3" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.3" "Cancer enriched" "Detected in single" 11 "liver cancer: 1.1" "Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA023694 Supported "Secreted to blood" "Complement pathway" NA NA 6700000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 1 "HPA023694: AB_1847128" "unprognostic (6.65e-2)" "prognostic favorable (9.31e-5)" "unprognostic (2.37e-1)" "unprognostic (2.37e-1)" "unprognostic (1.29e-2)" "unprognostic (6.57e-2)" "unprognostic (5.12e-3)" C8G ENSG00000176919 "Complement C8 gamma chain" P07360 9 136945185-136946975 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 550.5" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 1036.6" "Cancer enriched" "Detected in all" 58 "liver cancer: 260.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 6.2;liver cancer: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046269 Approved "Secreted to blood" "Complement pathway" NA NA 2800000000 "Cluster 31: Liver - Plasma proteins" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Hepatocytes - Metabolism" 2 "HPA046269: AB_2679606" "unprognostic (5.00e-2)" "unprognostic (4.05e-3)" "prognostic unfavorable (2.99e-4)" "unprognostic (3.94e-1)" "unprognostic (4.53e-1)" "unprognostic (2.75e-2)" "unprognostic (1.71e-3)" "unprognostic (2.79e-1)" "unprognostic (1.88e-1)" "unprognostic (3.67e-1)" "unprognostic (2.96e-2)" "unprognostic (3.00e-1)" "unprognostic (5.02e-3)" "unprognostic (2.16e-1)" "unprognostic (7.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.05e-2)" C9 ENSG00000113600 "Complement C9" P02748 5 39284140-39371324 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 264 "liver: 1268.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 1939.7" "Cancer enriched" "Detected in single" 244 "liver cancer: 90.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002151, HPA029577" Uncertain "Secreted to blood" "Complement pathway" NA NA 69600000000 64000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 59: Leukemia - T-cell receptor" "Cluster 62: Hepatocytes - Metabolism" 2 "CAB002151: AB_563670, HPA029577: AB_10603779" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (1.50e-1)" "unprognostic (2.01e-1)" "unprognostic (6.58e-2)" "unprognostic (1.30e-1)" "unprognostic (2.91e-1)" "unprognostic (5.49e-3)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (2.19e-2)" "unprognostic (9.43e-5)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "unprognostic (2.04e-1)" C9orf72 "DENND9, DENNL72, MGC23980" ENSG00000147894 "C9orf72-SMCR8 complex subunit" Q96LT7 9 27535640-27573866 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Guanine-nucleotide releasing factor" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 151.2;monocytes: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 24.3;classical monocyte: 32.0;intermediate monocyte: 44.8;myeloid DC: 25.2;neutrophil: 34.5;non-classical monocyte: 37.0" "Group enriched" "Detected in all" 8 "dendritic cells: 25.2;granulocytes: 34.5;monocytes: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023873 Uncertain Supported "Vesicles,Midbody ring,Cytosol" "Intracellular and membrane" Other Yes NA "Cluster 40: Monocytes - Innate immune response" "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 29: Monocytes - Innate immune response" 11 "Vesicles, Cytosol" "Midbody ring" "HPA023873: AB_1845834" "unprognostic (1.78e-2)" "unprognostic (5.01e-2)" "unprognostic (7.63e-2)" "unprognostic (9.78e-3)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (1.99e-3)" "unprognostic (2.45e-1)" "unprognostic (2.05e-2)" "unprognostic (2.16e-2)" "unprognostic (9.81e-2)" "unprognostic (1.44e-2)" "unprognostic (9.29e-2)" "unprognostic (1.10e-1)" "unprognostic (2.89e-2)" "unprognostic (9.13e-2)" CA10 "CA-RPX, CARPX, HUCEP-15" ENSG00000154975 "Carbonic anhydrase 10" Q9NS85 17 51630313-52160017 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 122.0;retina: 43.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 185.8;Excitatory neurons: 332.6;Oligodendrocyte precursor cells: 1508.4;Oocytes: 454.4" "Cancer enriched" "Detected in some" 4 "glioma: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.3;thyroid cancer: 4.2" "Colon - Colon enteroendocrine cells, Kidney - Podocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054825, HPA057837" Supported Approved Vesicles "Secreted in brain" "No annotated function" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 76: Oligodendrocyte precursor - Unknown function" Vesicles "HPA054825: AB_2682617, HPA057837: AB_2683542" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" "unprognostic (3.43e-1)" "unprognostic (8.22e-2)" "unprognostic (4.43e-3)" "unprognostic (1.02e-3)" "unprognostic (1.01e-1)" "unprognostic (5.91e-2)" "unprognostic (1.46e-1)" "unprognostic (7.21e-3)" "unprognostic (9.18e-5)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" CA11 "CARP2, CARPX1" ENSG00000063180 "Carbonic anhydrase 11" O75493 19 48637946-48646187 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "brain: 480.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.8;Hepatocytes: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "Rhabdoid: 124.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041778 Approved Vesicles,Microtubules "Secreted in brain" "No annotated function" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" "Vesicles, Microtubules" "HPA041778: AB_10794525" "unprognostic (1.39e-1)" "prognostic favorable (4.33e-4)" "unprognostic (2.59e-3)" "unprognostic (5.72e-2)" "unprognostic (1.54e-1)" "unprognostic (9.80e-3)" "unprognostic (6.02e-2)" "prognostic favorable (2.11e-5)" "unprognostic (3.79e-2)" "unprognostic (2.98e-1)" "prognostic favorable (8.60e-5)" "unprognostic (4.88e-2)" "unprognostic (8.64e-3)" "unprognostic (1.21e-1)" "unprognostic (7.15e-2)" "unprognostic (4.09e-3)" "unprognostic (1.75e-1)" CA6 ENSG00000131686 "Carbonic anhydrase 6" P23280 1 8945867-8975092 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 296 "salivary gland: 9125.4" "Cell type enriched" "Detected in some" 51 "Serous glandular cells: 8255.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 5.7;naive CD8 T-cell: 16.6" "Lineage enriched" "Detected in many" 12 "T-cells: 16.6" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.3" "Breast - Breast glandular cells (progenitors)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028550, HPA028692" Enhanced "Secreted to digestive system" Enzyme NA NA 24000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 6: Non-specific - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA028550: AB_10600105, HPA028692: AB_10601883" "unprognostic (2.54e-5)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "unprognostic (2.90e-1)" "unprognostic (9.28e-2)" "unprognostic (2.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (5.93e-2)" "unprognostic (4.41e-2)" "unprognostic (4.29e-5)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-1)" CABLES1 "FLJ35924, HsT2563" ENSG00000134508 "Cdk5 and Abl enzyme substrate 1" Q8TDN4 18 23134564-23260470 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.9" "Group enriched" "Detected in many" 4 "Astrocytes: 244.9;Oligodendrocyte precursor cells: 153.3" "Cancer enriched" "Detected in all" 5 "melanoma: 38.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073649 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Other NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 47: Astrocytes - Unknown function" 1 "Nucleoplasm, Nuclear bodies" "HPA073649: AB_2732233" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (1.56e-1)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "prognostic favorable (4.71e-6)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (4.80e-2)" "unprognostic (7.81e-2)" CABP1 ENSG00000157782 "Calcium binding protein 1" Q9NZU7 12 120640626-120667324 "Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "brain: 420.1" "Group enriched" "Detected in some" 4 "Bipolar cells: 108.3;Excitatory neurons: 287.3;Horizontal cells: 151.7" "Cancer enhanced" "Detected in some" "renal cancer: 2.2" "Region enhanced" "Detected in all" "cerebral cortex: 514.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 25 "Rhabdoid: 61.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 238.6" HPA051438 Uncertain "Intracellular and membrane" Other NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA051438: AB_2681486" "unprognostic (2.57e-1)" "unprognostic (4.79e-2)" "unprognostic (1.92e-4)" "unprognostic (1.16e-1)" "unprognostic (4.13e-3)" "unprognostic (6.28e-2)" "unprognostic (4.61e-2)" "unprognostic (2.85e-1)" "unprognostic (8.12e-3)" "unprognostic (7.59e-2)" "unprognostic (1.04e-2)" "unprognostic (6.60e-2)" "unprognostic (7.73e-3)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (3.61e-2)" "unprognostic (2.85e-1)" CACNA2D1 "alpha2delta-1, CACNA2, CACNL2A, LINC01112, lncRNA-N3, MHS3" ENSG00000153956 "Calcium voltage-gated channel auxiliary subunit alpha2delta 1" P54289 7 81946444-82443956 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 74.7;tongue: 72.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 524.8;Inhibitory neurons: 365.9;Oligodendrocyte precursor cells: 335.8;Oligodendrocytes: 616.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008213, HPA008621" Enhanced "Intracellular and membrane" Transport NA NA 390000000 "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 65: Neurons - Synaptic function" "HPA008213: AB_1233654, HPA008621: AB_1845863" "unprognostic (5.07e-3)" "unprognostic (2.21e-1)" "unprognostic (4.27e-3)" "unprognostic (2.92e-2)" "unprognostic (2.27e-1)" "unprognostic (1.39e-1)" "unprognostic (1.70e-1)" "unprognostic (3.22e-1)" "unprognostic (3.76e-1)" "unprognostic (2.05e-1)" "unprognostic (6.24e-3)" "unprognostic (2.23e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (4.28e-3)" "unprognostic (2.13e-1)" "unprognostic (9.18e-2)" "unprognostic (1.03e-4)" CADM3 "BIgR, FLJ10698, IGSF4B, Necl-1, NECL1, SynCAM3, TSLL1" ENSG00000162706 "Cell adhesion molecule 3" Q8N126 1 159171609-159203313 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 336.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 118.4;Excitatory neurons: 34.3;Horizontal cells: 55.4;Inhibitory neurons: 38.7;Melanocytes: 63.6;Muller glia cells: 31.9;Schwann cells: 88.4" "Cancer enriched" "Detected in many" 4 "glioma: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 55.7;skin cancer: 20.6" "Breast - Fibroblasts, Colon - Enteric glia cells, Lung - Fibroblast_2, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002981, CAB025746" Enhanced Supported "Intracellular and membrane" "Cell adhesion" NA NA 800000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 1 "CAB025746: , HPA002981: AB_1078916" "unprognostic (1.74e-2)" "unprognostic (8.26e-2)" "unprognostic (1.34e-2)" "unprognostic (1.33e-2)" "unprognostic (9.32e-2)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (6.12e-3)" "prognostic unfavorable (1.03e-5)" "unprognostic (5.52e-2)" "unprognostic (2.59e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (5.75e-4)" CALCA "CALC1, CGRP, CGRP-alpha" ENSG00000110680 "Calcitonin related polypeptide alpha" "P01258, P06881" 11 14966622-14972354 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, Transporters" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 172.4;thyroid gland: 149.5" "Cell type enriched" "Detected in some" 15 "Ionocytes: 371.5" "Cancer enriched" "Detected in many" 7 "lung cancer: 64.7" "Region enhanced" "Detected in many" "pons: 79.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 13 "thyroid cancer: 2800.5" "Colon - Colon enteroendocrine cells, Thyroid - Parafollicular cells" "Region enriched" "Detected in all" 5 "pons and medulla: 58.0" "HPA059886, HPA064453" Enhanced Supported "Secreted to blood" Hormone NA NA 51500 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Respiratory epithelial cells - Unknown function" 7 "HPA059886: , HPA064453: " "unprognostic (1.97e-1)" "prognostic unfavorable (4.49e-5)" "unprognostic (5.99e-2)" "unprognostic (2.42e-1)" "unprognostic (1.17e-1)" "unprognostic (6.45e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (3.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.74e-2)" "unprognostic (2.53e-3)" "unprognostic (1.02e-2)" CALCB "CALC2, CGRP-II, FLJ30166" ENSG00000175868 "Calcitonin related polypeptide beta" P10092 11 14904997-15082342 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Hormone "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 9.3;thyroid gland: 20.0" "Cell type enhanced" "Detected in some" "Melanocytes: 3.4;Oocytes: 2.2;Spermatocytes: 1.6;Spermatogonia: 4.3;T-cells: 1.2" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.2;endometrial cancer: 2.4;thyroid cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 19.8;colorectal cancer: 60.6;thyroid cancer: 62.5" "Colon - Colon enteroendocrine cells, Thyroid - Parafollicular cells" "Region enriched" "Detected in some" 7 "pons and medulla: 9.6" "Group enriched" "Detected in all" 5 "amygdala: 42.9;basal ganglia: 101.5;hypothalamus: 69.1;midbrain: 47.2;pons: 56.7" HPA059886 Supported "Secreted to blood" Hormone NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 7: T-cells - T-cell receptor" 1 "HPA059886: " "unprognostic (7.84e-2)" "unprognostic (4.07e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (3.42e-5)" "unprognostic (2.02e-1)" "unprognostic (8.40e-2)" "unprognostic (1.75e-1)" "unprognostic (7.21e-2)" "unprognostic (2.07e-1)" "unprognostic (3.32e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-1)" "unprognostic (1.02e-2)" "unprognostic (2.33e-2)" "unprognostic (2.66e-1)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" CALHM4 "C6orf78, FAM26D, FLJ32239" ENSG00000164451 "Calcium homeostasis modulator family member 4" Q5JW98 6 116529013-116561127 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 22.5" "Group enriched" "Detected in some" 47 "Cytotrophoblasts: 26.9;Syncytiotrophoblasts: 86.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "choroid plexus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "testis cancer: 1.6" "Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA048014 Approved "Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "Plasma membrane" "HPA048014: " "unprognostic (7.95e-2)" "unprognostic (3.44e-4)" "unprognostic (1.99e-1)" "unprognostic (1.44e-2)" CALR "cC1qR, CRT, FLJ26680, RO, SSA" ENSG00000179218 Calreticulin P27797 19 12938578-12944489 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1893.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001513, HPA002242, CAB019952, CAB079775, CAB080301" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA 210000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 63 "Endoplasmic reticulum" "CAB001513: , CAB019952: AB_2069792, CAB079775: AB_303403, CAB080301: , HPA002242: AB_1078384" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (8.46e-2)" "unprognostic (4.25e-2)" "unprognostic (9.44e-3)" "unprognostic (6.93e-2)" "unprognostic (2.47e-2)" "unprognostic (4.60e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.07e-1)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (2.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.37e-1)" "unprognostic (5.27e-2)" CALR3 "CRT2, CT93, FLJ25355, MGC26577" ENSG00000269058 "Calreticulin 3" Q96L12 19 16479061-16496167 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" Chaperone "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "testis: 63.0" "Group enriched" "Detected in some" 6 "Early spermatids: 31.4;Late spermatids: 20.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025749, HPA043355, HPA048460" Enhanced "Intracellular and membrane" Other NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 13: Spermatids - Transcription" "CAB025749: , HPA043355: AB_2678442, HPA048460: AB_2680403" "unprognostic (1.19e-1)" "unprognostic (3.84e-1)" "unprognostic (7.17e-2)" "unprognostic (4.34e-1)" "unprognostic (2.32e-1)" "unprognostic (2.95e-1)" "unprognostic (1.30e-2)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (1.18e-2)" "unprognostic (6.69e-7)" "unprognostic (1.60e-1)" "unprognostic (2.78e-1)" "unprognostic (6.28e-3)" "unprognostic (6.34e-3)" CALU ENSG00000128595 Calumenin O43852 7 128739292-128773400 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 319.1;Extravillous trophoblasts: 612.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006018, HPA071040" Supported Enhanced "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 21000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA006018: AB_1845934, HPA071040: " "unprognostic (7.22e-3)" "unprognostic (1.16e-3)" "unprognostic (3.16e-1)" "unprognostic (8.86e-2)" "unprognostic (1.27e-1)" "unprognostic (9.52e-3)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.05e-3)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.75e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.30e-11)" "unprognostic (3.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.60e-5)" CAMP "CAP18, FALL-39, FALL39, LL37" ENSG00000164047 "Cathelicidin antimicrobial peptide" P49913 3 48223347-48225491 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "bone marrow: 2882.0" "Cell type enriched" "Detected in some" 14 "Serous glandular cells: 278.0" "Cancer enriched" "Detected in many" 4 "testis cancer: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "eosinophil: 84.7;neutrophil: 337.5" "Lineage enriched" "Detected in many" 12 "granulocytes: 337.5" "Cancer enhanced" "Detected in some" "breast cancer: 3.7;lymphoma: 11.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB015949, CAB016522, HPA029874" Enhanced "Secreted to blood" Immunity NA NA 617000000 28000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 6: Bone marrow - Innate immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 75: Serous glandular cells - Salivary secretion" "CAB015949: , CAB016522: , HPA029874: AB_10600859" "unprognostic (2.14e-2)" "prognostic favorable (5.73e-4)" "unprognostic (4.59e-2)" "unprognostic (2.62e-1)" "unprognostic (9.41e-2)" "unprognostic (4.57e-5)" "unprognostic (3.09e-1)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (7.65e-2)" "unprognostic (1.32e-1)" "unprognostic (8.08e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-1)" "unprognostic (1.71e-1)" "unprognostic (1.80e-2)" "unprognostic (1.03e-2)" CARM1 PRMT4 ENSG00000142453 "Coactivator associated arginine methyltransferase 1" Q86X55 19 10871553-10923075 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032961, HPA043561, HPA048073, HPA069313" Supported Enhanced Nucleoplasm "Intracellular and membrane" Transcription NA NA 19000 "Cluster 79: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 7 Nucleoplasm "CAB032961: AB_2068446, HPA043561: AB_2678554, HPA048073: AB_2680250, HPA069313: " "unprognostic (9.46e-2)" "unprognostic (3.61e-1)" "unprognostic (2.94e-2)" "unprognostic (2.23e-1)" "unprognostic (2.69e-2)" "unprognostic (3.13e-2)" "unprognostic (1.66e-3)" "unprognostic (3.76e-2)" "unprognostic (7.81e-2)" "unprognostic (6.18e-2)" "unprognostic (9.31e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (7.88e-6)" "unprognostic (1.71e-2)" "unprognostic (6.26e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (8.37e-4)" CARNS1 "ATPGD1, KIAA1394" ENSG00000172508 "Carnosine synthase 1" A5YM72 11 67414968-67425607 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 265.6;skeletal muscle: 72.2" "Cell type enriched" "Detected in some" 14 "Oligodendrocytes: 416.8" "Group enriched" "Detected in many" 5 "glioma: 4.1;thyroid cancer: 10.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA038569 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Oligodendrocytes - Unknown function" "HPA038569: AB_2676089" "unprognostic (1.07e-4)" "unprognostic (4.33e-3)" "unprognostic (2.00e-2)" "unprognostic (6.15e-2)" "unprognostic (9.45e-2)" "unprognostic (1.05e-1)" "unprognostic (7.28e-2)" "unprognostic (7.54e-3)" "unprognostic (1.29e-1)" "unprognostic (1.82e-1)" "unprognostic (5.19e-3)" "unprognostic (1.00e-1)" "unprognostic (6.14e-6)" "unprognostic (3.44e-2)" "unprognostic (1.33e-1)" "unprognostic (3.83e-3)" "unprognostic (8.33e-2)" CARTPT CART ENSG00000164326 "CART prepropeptide" Q16568 5 71719275-71721048 "FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 520.9" "Group enriched" "Detected in some" 5 "Early spermatids: 35.6;Horizontal cells: 141.6;Spermatocytes: 44.4" "Cancer enriched" "Detected in many" 9 "breast cancer: 117.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Neuroblastoma: 24.8" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 307.9" "CAB025515, HPA046278, CAB079776" Enhanced Supported "Secreted to blood" Neuropeptide NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 2 "CAB025515: , CAB079776: , HPA046278: AB_10961570" "unprognostic (1.37e-1)" "unprognostic (1.43e-1)" "unprognostic (2.27e-1)" "unprognostic (3.45e-2)" "unprognostic (6.67e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.14e-1)" CASP4 "ICE(rel)II, ICH-2, TX" ENSG00000196954 "Caspase 4" P49662 11 104942866-104969366 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "HPA027588, CAB037167" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Immunity NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" Cytosol "Plasma membrane" "CAB037167: AB_258864, HPA027588: AB_10603781" "unprognostic (1.19e-2)" "unprognostic (3.73e-1)" "unprognostic (3.44e-1)" "unprognostic (1.99e-2)" "unprognostic (7.19e-3)" "unprognostic (2.63e-2)" "unprognostic (1.26e-2)" "unprognostic (1.56e-2)" "unprognostic (5.31e-2)" "unprognostic (2.71e-1)" "unprognostic (2.38e-3)" "unprognostic (8.39e-3)" "prognostic unfavorable (3.27e-11)" "unprognostic (6.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-2)" "unprognostic (4.08e-3)" CASP7 "CMH-1, ICE-LAP3, MCH3" ENSG00000165806 "Caspase 7" P55210 10 113679162-113730907 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Allosteric enzyme, Hydrolase, Protease, RNA-binding, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 152.6;Proximal enterocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025563 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 5: Enterocytes - Absorption" 10 "CAB025563: " "prognostic favorable (2.11e-4)" "unprognostic (3.18e-2)" "unprognostic (2.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-3)" "unprognostic (3.96e-1)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "prognostic unfavorable (5.90e-4)" "unprognostic (5.45e-3)" "unprognostic (2.62e-1)" "unprognostic (2.86e-1)" "unprognostic (4.33e-3)" CASQ1 "CASQ, PDIB1" ENSG00000143318 "Calsequestrin 1" P31415 1 160190575-160201886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 63 "skeletal muscle: 4285.4;tongue: 1819.0" "Cell type enriched" "Detected in some" 8 "Skeletal myocytes: 194.2" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.8;testis cancer: 3.1" "Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007845, CAB015170, HPA026823" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Other NA NA 270000 "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 2: Skeletal myocytes - Muscle contraction" 1 "Nucleoplasm, Mitochondria" "CAB015170: AB_2071451, HPA007845: AB_1078388, HPA026823: AB_10603557" "unprognostic (1.87e-2)" "unprognostic (3.97e-3)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (6.85e-2)" "unprognostic (1.96e-2)" "unprognostic (4.65e-3)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (2.87e-2)" "unprognostic (3.01e-2)" "unprognostic (3.21e-3)" "unprognostic (9.04e-4)" "unprognostic (1.80e-1)" "unprognostic (1.58e-1)" "prognostic favorable (8.93e-5)" CASQ2 PDIB2 ENSG00000118729 "Calsequestrin 2" O14958 1 115700021-115768714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1019.4" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 966.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 2.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Endothelial cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in all" 6 "cerebellum: 43.1" "Low region specificity" "Detected in many" "HPA027285, HPA055298" Enhanced "Intracellular and membrane" Other NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 "HPA027285: AB_1845933, HPA055298: AB_2682777" "unprognostic (1.13e-1)" "unprognostic (1.52e-1)" "unprognostic (9.70e-3)" "unprognostic (1.28e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.03e-4)" "unprognostic (1.78e-1)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (7.20e-3)" "unprognostic (1.82e-2)" "unprognostic (1.80e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.25e-5)" CATSPERG "C19orf15, DKFZp434A1022, FLJ46353" ENSG00000099338 "Cation channel sperm associated auxiliary subunit gamma" Q6ZRH7 19 38335775-38370943 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 30.5" "Cell type enhanced" "Detected in many" "Early spermatids: 25.1;Gastric mucus-secreting cells: 22.4;Late spermatids: 47.2;Proximal enterocytes: 18.4;Spermatocytes: 25.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052777 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in male reproductive system" "Developmental protein" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 42: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoli "Nucleoplasm, Cytosol" "HPA052777: " "unprognostic (8.50e-5)" "unprognostic (5.12e-2)" "unprognostic (3.57e-3)" "unprognostic (1.51e-1)" "unprognostic (2.63e-1)" "unprognostic (3.18e-1)" "unprognostic (2.60e-1)" "unprognostic (2.87e-3)" "unprognostic (1.00e-1)" "unprognostic (2.92e-2)" "unprognostic (1.06e-1)" "unprognostic (2.50e-1)" "unprognostic (4.37e-4)" "unprognostic (9.99e-2)" "unprognostic (2.01e-1)" "unprognostic (4.61e-2)" "unprognostic (1.07e-3)" CBLIF "GIF, IF, IFMH, INF, TCN3" ENSG00000134812 "Cobalamin binding intrinsic factor" P27352 11 59829273-59845499 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1873 "stomach 1: 1533.7" "Cell type enriched" "Detected in some" 64 "Gastric mucus-secreting cells: 339.6" "Cancer enriched" "Detected in some" 11 "stomach cancer: 10.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "ovarian cancer: 1.0" "Stomach - Parietal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039908, HPA040774" Enhanced "Secreted to digestive system" Transport NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" 5 "HPA039908: AB_10796335, HPA040774: AB_10795626" "unprognostic (2.78e-4)" "unprognostic (1.04e-1)" "unprognostic (2.45e-1)" "unprognostic (3.59e-1)" "unprognostic (1.66e-1)" CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 439.8" "Cell type enhanced" "Detected in some" "Early spermatids: 97.7;Late spermatids: 294.6;Spermatocytes: 52.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.5" "Region enriched" "Detected in all" 4 "cerebellum: 239.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 12.2;Neuroblastoma: 18.5" "Breast - Adipocytes (Breast), Skin - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in all" 13 "cerebellum: 493.5" "Secreted in brain" "No annotated function" NA NA 6000000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 63: Late spermatids - Spermatogenesis" "unprognostic (1.39e-2)" "unprognostic (1.88e-2)" "unprognostic (1.53e-1)" "unprognostic (3.16e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-2)" "unprognostic (9.65e-3)" "unprognostic (1.18e-2)" "unprognostic (6.31e-2)" "unprognostic (1.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.04e-2)" "unprognostic (7.68e-2)" "unprognostic (2.45e-1)" "unprognostic (1.06e-2)" "prognostic favorable (7.10e-4)" "unprognostic (1.60e-2)" CBLN2 ENSG00000141668 "Cerebellin 2 precursor" Q8IUK8 18 72536680-72638521 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 40.1" "Cell type enriched" "Detected in some" 25 "Excitatory neurons: 492.2" "Cancer enriched" "Detected in single" 7 "breast cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 36.9;Sarcoma: 13.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in brain" "No annotated function" NA NA 1400000 "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (2.03e-2)" "unprognostic (3.52e-1)" "unprognostic (1.13e-3)" "unprognostic (9.09e-5)" "unprognostic (7.10e-2)" "unprognostic (6.27e-3)" "unprognostic (7.39e-2)" "unprognostic (2.17e-1)" "unprognostic (1.37e-4)" "unprognostic (5.01e-4)" "unprognostic (8.15e-2)" "unprognostic (6.07e-4)" "unprognostic (7.19e-2)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (4.93e-2)" CBLN3 ENSG00000139899 "Cerebellin 3 precursor" Q6UW01 14 24426545-24430954 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "brain: 402.6" "Cell type enhanced" "Detected in some" "dendritic cells: 4.0;Ovarian stromal cells: 3.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 12 "cerebellum: 199.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.5" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Region enriched" "Detected in many" 25 "cerebellum: 429.9" "Region enriched" "Detected in many" 43 "cerebellum: 596.8" HPA041266 Enhanced Supported Approved Nucleoplasm "Secreted in brain" "No annotated function" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" Nucleoplasm "HPA041266: AB_10674430" "unprognostic (5.02e-2)" "unprognostic (3.26e-1)" "unprognostic (1.43e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (4.39e-4)" "unprognostic (5.39e-3)" "unprognostic (1.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.16e-2)" "unprognostic (9.76e-2)" "unprognostic (6.20e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (6.20e-6)" "unprognostic (2.75e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (9.02e-2)" CBLN4 "CBLNL1, dJ885A10.1" ENSG00000054803 "Cerebellin 4 precursor" Q9NTU7 20 55997357-56005519 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 17.3;brain: 17.3;epididymis: 8.6" "Group enriched" "Detected in some" 6 "Excitatory neurons: 26.1;Inhibitory neurons: 29.9;Peritubular cells: 36.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074497 Supported "Secreted in brain" "No annotated function" NA NA 10000000 "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 65: Neurons - Synaptic function" "HPA074497: " "unprognostic (3.61e-1)" "unprognostic (8.43e-3)" "unprognostic (2.43e-1)" "unprognostic (1.61e-2)" "unprognostic (1.99e-1)" "unprognostic (4.00e-1)" "unprognostic (3.25e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (3.88e-1)" "unprognostic (9.63e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-3)" "unprognostic (3.22e-4)" "unprognostic (7.50e-2)" "unprognostic (3.58e-2)" "unprognostic (1.79e-3)" CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 26.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.5;Granulosa cells: 53.5;Mesothelial cells: 24.9;Oocytes: 63.2;Ovarian stromal cells: 57.9;Rod photoreceptor cells: 43.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 8.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 8.9" "Group enriched" "Detected in many" 4 "Adrenocortical cancer: 56.8;thyroid cancer: 19.4" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblast_2" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in all" "HPA041361, HPA041374" Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Ovarian stromal cells - Transcription" 3 "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" CCDC112 MGC39633 ENSG00000164221 "Coiled-coil domain containing 112" Q8NEF3 5 115267190-115296693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 39.5" "Cell type enhanced" "Detected in many" "Spermatocytes: 175.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045120, HPA050621" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 46: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Spermatocytes - Spermatogenesis" 4 "Plasma membrane, Cytosol" Nucleoplasm "HPA045120: AB_2679222, HPA050621: AB_2681191" "unprognostic (1.88e-2)" "unprognostic (5.10e-2)" "unprognostic (4.63e-2)" "unprognostic (5.60e-3)" "unprognostic (2.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.32e-6)" "unprognostic (4.30e-2)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (3.33e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (1.51e-6)" "unprognostic (7.00e-2)" "unprognostic (2.79e-2)" "unprognostic (8.61e-2)" "unprognostic (4.10e-3)" CCDC126 FLJ23031 ENSG00000169193 "Coiled-coil domain containing 126" Q96EE4 7 23597382-23644708 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 33.7" "Group enriched" "Detected in all" 18 "Early spermatids: 602.5;Late spermatids: 593.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 480.6" "Lineage enriched" "Detected in all" 23 "granulocytes: 480.6" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010969, HPA026883" Uncertain Approved "Golgi apparatus" "Secreted to blood" "No annotated function" NA NA 39000000 "Cluster 46: Basophils - Proteolysis" "Cluster 78: Testis - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 11: Late spermatids - Unknown function" "Golgi apparatus" "HPA010969: , HPA026883: AB_1846131" "unprognostic (2.02e-1)" "unprognostic (2.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (5.96e-3)" "unprognostic (1.16e-2)" "unprognostic (3.90e-1)" "unprognostic (9.30e-2)" "unprognostic (1.42e-2)" "unprognostic (3.44e-2)" "unprognostic (3.29e-2)" "unprognostic (7.35e-3)" "unprognostic (5.90e-2)" "unprognostic (1.20e-1)" "unprognostic (1.62e-1)" "unprognostic (3.28e-1)" CCDC134 FLJ22349 ENSG00000100147 "Coiled-coil domain containing 134" Q9H6E4 22 41800679-41832164 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003936, HPA075348" Approved Supported Vesicles,Cytosol "Secreted to blood" "No annotated function" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cell proliferation" 1 Cytosol Vesicles "HPA003936: AB_1078419, HPA075348: " "unprognostic (2.09e-2)" "unprognostic (1.00e-1)" "unprognostic (3.82e-2)" "prognostic favorable (4.09e-4)" "unprognostic (1.73e-1)" "unprognostic (3.85e-2)" "prognostic unfavorable (7.42e-7)" "unprognostic (4.35e-1)" "unprognostic (1.69e-1)" "unprognostic (3.08e-1)" "unprognostic (3.30e-2)" "unprognostic (7.32e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.24e-3)" "unprognostic (2.52e-2)" "unprognostic (5.47e-1)" "unprognostic (6.63e-2)" CCDC3 DKFZp761F241 ENSG00000151468 "Coiled-coil domain containing 3" Q9BQI4 10 12896625-13099652 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 128.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 96.7;Inhibitory neurons: 39.5;Oocytes: 50.0;Ovarian stromal cells: 52.9;Peritubular cells: 56.6;Smooth muscle cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 21.9" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Liver - Hepatic stellate cells, Lung - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 27.4" HPA062425 Uncertain Nucleoplasm,Cytosol "Secreted to blood" "No annotated function" NA NA "Cluster 13: Skin - Cornification" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Smooth muscle cells - Signal transduction" Cytosol Nucleoplasm "HPA062425: AB_2684759" "unprognostic (2.26e-1)" "unprognostic (6.65e-3)" "unprognostic (1.70e-1)" "unprognostic (4.30e-3)" "unprognostic (1.72e-1)" "unprognostic (5.08e-2)" "unprognostic (3.11e-2)" "unprognostic (2.99e-2)" "unprognostic (5.56e-3)" "unprognostic (5.41e-2)" "unprognostic (4.25e-3)" "unprognostic (2.22e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.54e-2)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (3.88e-2)" CCDC80 "CL2, DRO1, LINC01279, SSG1, TCONS_00006930, URB" ENSG00000091986 "Coiled-coil domain containing 80" Q76M96 3 112596797-112649530 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 314.6;Fibroblasts: 1151.0;Late spermatids: 484.8;Lymphatic endothelial cells: 298.9;Mesothelial cells: 817.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002266 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 510000 "Cluster 62: Connective tissue - ECM organization" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA002266: AB_1078423" "unprognostic (1.26e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-2)" "unprognostic (3.19e-1)" "unprognostic (2.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.82e-1)" "unprognostic (2.53e-2)" "unprognostic (2.30e-3)" "unprognostic (1.99e-3)" "unprognostic (8.40e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.86e-5)" "unprognostic (5.97e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.26e-4)" CCDC85A KIAA1912 ENSG00000055813 "Coiled-coil domain containing 85A" Q96PX6 2 56183990-56386172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.1;brain: 12.4" "Group enriched" "Detected in some" 4 "Excitatory neurons: 221.4;Inhibitory neurons: 153.4;Microglial cells: 57.3" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043106, HPA057020" Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 65: Neurons - Synaptic function" "HPA043106: AB_10794770, HPA057020: AB_2683311" "unprognostic (2.29e-1)" "unprognostic (1.28e-1)" "unprognostic (6.87e-2)" "unprognostic (3.66e-2)" "unprognostic (7.87e-2)" "unprognostic (7.62e-2)" "unprognostic (3.07e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-1)" "unprognostic (6.55e-5)" "unprognostic (3.28e-2)" "unprognostic (1.00e-1)" "unprognostic (2.88e-2)" "unprognostic (1.83e-2)" CCDC88B "BRLZ, CCDC88, FLJ00354, FLJ37970, GIPIE, HkRP3" ENSG00000168071 "Coiled-coil domain containing 88B" A6NC98 11 64340204-64357534 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 82.9;lymphoid tissue: 84.0" "Cell type enhanced" "Detected in many" "NK-cells: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "head and neck cancer: 5.7;Leukemia: 22.5;lymphoma: 20.2;Myeloma: 15.4" "Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA026652 Approved Supported Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" Other NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 35: RS4;11 - Unknown function" "Cluster 5: Enterocytes - Absorption" 32 "Centrosome, Cytosol" Nucleoplasm "HPA026652: AB_1846168" "unprognostic (1.18e-2)" "unprognostic (3.33e-3)" "unprognostic (3.65e-1)" "unprognostic (1.58e-2)" "unprognostic (2.36e-1)" "prognostic favorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (1.55e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-1)" "unprognostic (2.94e-1)" "unprognostic (7.32e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.77e-2)" "unprognostic (7.38e-2)" "unprognostic (1.90e-1)" "unprognostic (2.83e-2)" CCER2 ENSG00000262484 "Coiled-coil glutamate rich protein 2" I3L3R5 19 38908980-38912186 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.8;testis: 4.7" "Cell type enriched" "Detected in some" 11 "Melanocytes: 599.5" "Group enriched" "Detected in many" 5 "glioma: 5.1;testis cancer: 1.9;urothelial cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069716 Uncertain "Secreted - unknown location" "No annotated function" NA NA 8800 "Cluster 21: Testis - Unknown function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 11: Neuronal - Sensory perception" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "HPA069716: AB_2686183" "unprognostic (6.58e-2)" "unprognostic (2.24e-2)" "unprognostic (5.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (2.76e-3)" "unprognostic (3.88e-2)" "unprognostic (2.16e-1)" "unprognostic (5.97e-2)" "unprognostic (1.45e-1)" "unprognostic (4.08e-3)" "unprognostic (3.82e-2)" "unprognostic (1.01e-9)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.32e-4)" CCK ENSG00000187094 Cholecystokinin P06307 3 42257825-42266185 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 435.6;intestine: 112.3" "Cell type enhanced" "Detected in some" "Astrocytes: 38.1;Enteroendocrine cells: 115.6;Excitatory neurons: 149.6;Inhibitory neurons: 150.9;Melanocytes: 37.8;Muller glia cells: 36.2;Oligodendrocytes: 38.0" "Group enriched" "Detected in many" 5 "glioma: 4.0;pancreatic cancer: 1.8;prostate cancer: 3.5;stomach cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Bone cancer: 82.2;Gastric cancer: 52.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 107.8" "HPA045039, HPA069515" Enhanced Supported "Secreted to blood" Hormone NA NA 43700000 "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 32 "HPA045039: , HPA069515: AB_2732135" "unprognostic (3.36e-1)" "unprognostic (1.58e-1)" "unprognostic (1.92e-1)" "unprognostic (1.40e-3)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (2.39e-3)" "unprognostic (1.97e-2)" "unprognostic (3.91e-1)" "unprognostic (8.77e-2)" "unprognostic (1.35e-1)" "unprognostic (2.42e-1)" "unprognostic (1.37e-1)" "unprognostic (5.10e-2)" CCL1 "I-309, P500, SCYA1, SISe, TCA3" ENSG00000108702 "C-C motif chemokine ligand 1" P22362 17 34360328-34363233 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 2.1;lymphoid tissue: 1.2" "Group enriched" "Detected in some" 4 "Early spermatids: 1.3;Late spermatids: 1.9;T-cells: 2.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Leukemia: 7.9;lymphoma: 28.6" "Testis - Late spermatids" HPA049861 Uncertain "Secreted to blood" Chemokine NA NA 84400 "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 30: Granulocytes - Unknown function" "HPA049861: AB_2680919" "unprognostic (6.52e-2)" "unprognostic (4.81e-3)" "unprognostic (5.84e-2)" "unprognostic (5.01e-1)" "unprognostic (6.04e-1)" "unprognostic (2.71e-1)" "unprognostic (1.37e-1)" CCL11 "eotaxin, MGC22554, SCYA11" ENSG00000172156 "C-C motif chemokine ligand 11" P51671 17 34285742-34288334 "Cancer-related genes, Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.3;lymphoid tissue: 30.5;stomach 1: 34.1;urinary bladder: 39.5" "Cell type enriched" "Detected in some" 21 "Fibroblasts: 28.3" "Cancer enhanced" "Detected in many" "stomach cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Chemokine NA NA 88500 "Cluster 45: Intestine - Digestion" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 49: Non-specific - Transcription" 4 "unprognostic (4.61e-2)" "unprognostic (1.45e-1)" "prognostic favorable (8.70e-4)" "unprognostic (8.18e-2)" "prognostic favorable (1.99e-4)" "unprognostic (9.91e-2)" "unprognostic (8.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "unprognostic (1.45e-1)" "unprognostic (9.64e-8)" "unprognostic (2.66e-2)" "unprognostic (1.05e-3)" "unprognostic (1.61e-1)" "unprognostic (2.72e-2)" CCL13 "CKb10, MCP-4, MGC17134, NCC-1, SCYA13, SCYL1" ENSG00000181374 "C-C motif chemokine ligand 13" Q99616 17 34356480-34358610 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.4;urinary bladder: 29.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 44.8;Langerhans cells: 17.4;Macrophages: 80.4;Melanocytes: 12.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Chemokine NA NA 336000 "Cluster 45: Intestine - Digestion" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 3 "unprognostic (2.22e-2)" "unprognostic (3.56e-2)" "unprognostic (8.41e-3)" "unprognostic (1.49e-3)" "unprognostic (4.43e-2)" "unprognostic (1.58e-1)" "unprognostic (7.58e-2)" "unprognostic (8.49e-2)" "unprognostic (1.18e-1)" "unprognostic (2.83e-2)" "unprognostic (1.35e-2)" "unprognostic (5.98e-2)" "unprognostic (8.63e-8)" "unprognostic (2.26e-1)" "unprognostic (2.57e-1)" "unprognostic (1.37e-1)" "unprognostic (1.71e-2)" CCL14 "CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYA14, SCYL2" ENSG00000276409 "C-C motif chemokine ligand 14" Q16627 17 35983288-35987004 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 617.4" "Cell type enhanced" "Detected in some" "Adipocytes: 122.4;Endothelial cells: 261.5;Fibroblasts: 83.0;Kupffer cells: 45.1;Late spermatids: 55.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 6 "choroid plexus: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Endothelial cells, Colon - Endothelial cells, Liver - Sinusoid Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "CAB004423, HPA030268" Uncertain "Secreted to blood" Chemokine NA NA 5200000 37000000 "Cluster 47: Spleen - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "CAB004423: AB_627716, HPA030268: AB_10603782" "unprognostic (4.13e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "unprognostic (3.55e-3)" "unprognostic (2.50e-1)" "unprognostic (1.99e-2)" "unprognostic (8.79e-5)" "unprognostic (1.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (6.33e-3)" "unprognostic (3.00e-2)" "unprognostic (7.27e-3)" "unprognostic (1.36e-2)" "unprognostic (3.95e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" CCL15 "HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3" ENSG00000275718 "C-C motif chemokine ligand 15" Q16663 17 35996440-36001553 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 80.2;liver: 30.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 248.6;Enteroendocrine cells: 98.2;Intestinal goblet cells: 170.4;Paneth cells: 297.1;Proximal enterocytes: 484.4;Undifferentiated cells: 104.6" "Cancer enhanced" "Detected in many" "liver cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "colorectal cancer: 24.6;Gastric cancer: 10.9;liver cancer: 14.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells" HPA058608 Approved "Golgi apparatus,Vesicles" "Secreted to blood" Chemokine NA NA 3270000 11000000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Golgi apparatus" Vesicles "HPA058608: AB_2683776" "unprognostic (1.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-2)" "unprognostic (1.40e-1)" "unprognostic (8.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" "unprognostic (2.41e-2)" "unprognostic (1.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.15e-1)" "unprognostic (1.07e-2)" "prognostic favorable (3.02e-4)" CCL16 "CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYA16, SCYL4" ENSG00000275152 "C-C motif chemokine ligand 16" O15467 17 35976493-35981497 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "liver: 116.5" "Cell type enriched" "Detected in some" 71 "Hepatocytes: 272.3" "Cancer enriched" "Detected in single" 154 "liver cancer: 49.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Low region specificity" "Detected in many" "Secreted to blood" Chemokine NA NA 2780000 23000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 2 "unprognostic (3.85e-1)" "unprognostic (4.71e-1)" "unprognostic (1.49e-1)" "unprognostic (3.75e-2)" "unprognostic (2.72e-1)" "unprognostic (4.58e-2)" "unprognostic (2.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.54e-1)" "unprognostic (1.91e-2)" "unprognostic (3.57e-1)" "unprognostic (1.40e-3)" "unprognostic (1.66e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (4.08e-2)" CCL17 "ABCD-2, SCYA17, TARC" ENSG00000102970 "C-C motif chemokine ligand 17" Q92583 16 57404767-57416063 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 20.5" "Group enriched" "Detected in some" 5 "Langerhans cells: 143.4;Macrophages: 54.3;Pancreatic endocrine cells: 207.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 39 "lymphoma: 215.8" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 5.7" CAB002583 Uncertain "Secreted to blood" Chemokine NA NA 248000 "Cluster 71: Thymus - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 14: Langerhans cells - Innate immune response" 7 "CAB002583: AB_564022" "unprognostic (4.62e-3)" "prognostic favorable (1.91e-5)" "unprognostic (5.83e-2)" "unprognostic (3.52e-4)" "unprognostic (4.51e-2)" "unprognostic (1.78e-3)" "unprognostic (4.44e-1)" "unprognostic (3.41e-2)" "unprognostic (6.36e-2)" "unprognostic (4.28e-2)" "unprognostic (4.11e-1)" "unprognostic (2.91e-2)" "unprognostic (6.04e-2)" "unprognostic (2.35e-1)" "unprognostic (7.72e-3)" "unprognostic (4.14e-3)" "prognostic favorable (5.80e-4)" CCL18 "AMAC-1, CKb7, DC-CK1, DCCK1, MIP-4, PARC, SCYA18" ENSG00000275385 "C-C motif chemokine ligand 18" P55774 17 36064272-36072032 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lung: 47.3" "Group enriched" "Detected in some" 6 "Hofbauer cells: 168.1;Macrophages: 205.7" "Cancer enhanced" "Detected in all" "lung cancer: 76.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Lung - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Secreted to blood" Chemokine NA NA 55500000 6400000 "Cluster 57: Lung - Lung function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" 1 "unprognostic (8.91e-2)" "unprognostic (2.96e-2)" "unprognostic (5.71e-2)" "unprognostic (9.64e-2)" "unprognostic (1.60e-2)" "unprognostic (3.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.96e-1)" "unprognostic (2.50e-1)" "unprognostic (3.11e-2)" "unprognostic (1.21e-2)" "unprognostic (4.06e-2)" "unprognostic (2.95e-3)" "unprognostic (2.49e-1)" "unprognostic (1.68e-1)" "unprognostic (3.63e-1)" "unprognostic (4.87e-2)" CCL19 "CKb11, ELC, exodus-3, MIP-3b, SCYA19" ENSG00000172724 "C-C motif chemokine ligand 19" Q99731 9 34689570-34691276 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 616.5" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 51.6;Fibroblasts: 59.0;Langerhans cells: 70.9;Smooth muscle cells: 151.4" "Cancer enhanced" "Detected in all" "testis cancer: 118.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 25 "breast cancer: 9.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067758 Enhanced "Secreted to blood" Chemokine NA NA 195000 63000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 8: Immune cells - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA067758: AB_2685897" "prognostic favorable (2.88e-5)" "prognostic favorable (9.91e-6)" "unprognostic (8.25e-3)" "unprognostic (1.16e-1)" "unprognostic (1.65e-1)" "unprognostic (1.67e-2)" "unprognostic (1.30e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (8.36e-3)" "unprognostic (8.31e-2)" "unprognostic (2.43e-1)" "prognostic unfavorable (8.63e-7)" "unprognostic (7.98e-2)" "unprognostic (1.68e-2)" "unprognostic (2.03e-1)" "unprognostic (1.87e-1)" CCL2 "GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF" ENSG00000108691 "C-C motif chemokine ligand 2" P13500 17 34255274-34257208 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 726.7" "Cell type enhanced" "Detected in many" "Ductal cells: 2990.5;Exocrine glandular cells: 1242.1;Pancreatic endocrine cells: 1696.3;Secretory cells: 2061.7;Smooth muscle cells: 1284.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 7.6;eosinophil: 3.1" "Group enriched" "Detected in many" 6 "granulocytes: 3.1;monocytes: 7.6" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 4 "midbrain: 13.1;spinal cord: 52.4" "CAB013676, HPA019163" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" Chemokine NA NA 323000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - Signal transduction" 4 "Golgi apparatus" Vesicles "CAB013676: , HPA019163: AB_1846179" "unprognostic (6.43e-2)" "unprognostic (4.14e-2)" "unprognostic (4.78e-2)" "unprognostic (5.57e-2)" "unprognostic (2.37e-3)" "unprognostic (8.64e-2)" "unprognostic (2.78e-2)" "unprognostic (7.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" "unprognostic (9.33e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (1.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.81e-1)" "unprognostic (4.92e-2)" CCL20 "CKb4, exodus-1, LARC, MIP-3a, SCYA20, ST38" ENSG00000115009 "C-C motif chemokine ligand 20" P78556 2 227805739-227817564 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Antibiotic, Antimicrobial, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 157.4;lymphoid tissue: 160.8;urinary bladder: 185.8" "Group enriched" "Detected in many" 8 "Basal respiratory cells: 29078.1;Ionocytes: 11382.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.7" "Lineage enriched" "Detected in single" 9 "T-cells: 2.7" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Chemokine NA NA 28000 "Cluster 1: T-cells - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "unprognostic (2.40e-1)" "unprognostic (1.31e-3)" "unprognostic (1.30e-1)" "unprognostic (2.87e-2)" "unprognostic (7.06e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (9.29e-4)" "unprognostic (1.53e-3)" "unprognostic (1.37e-1)" "unprognostic (5.21e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.19e-8)" "unprognostic (1.39e-1)" "unprognostic (2.75e-1)" "unprognostic (1.63e-1)" "unprognostic (1.82e-1)" CCL21 "6Ckine, CKb9, ECL, exodus-2, SCYA21, SLC, TCA4" ENSG00000137077 "C-C motif chemokine ligand 21" O00585 9 34709005-34710136 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 2658.3" "Cell type enriched" "Detected in many" 15 "Lymphatic endothelial cells: 19541.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA051210 Enhanced "Secreted to blood" Chemokine NA NA 198000 920000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 8 "HPA051210: AB_2681390" "unprognostic (3.06e-3)" "unprognostic (7.19e-3)" "unprognostic (9.89e-2)" "unprognostic (5.50e-2)" "unprognostic (4.51e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" "unprognostic (8.07e-2)" "unprognostic (4.15e-2)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (8.99e-3)" "unprognostic (3.50e-3)" "unprognostic (1.58e-1)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" CCL22 "A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, SCYA22, STCP-1" ENSG00000102962 "C-C motif chemokine ligand 22" O00626 16 57358783-57366189 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 14.4;skin 1: 6.4" "Cell type enriched" "Detected in some" 10 "Langerhans cells: 259.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "lymphoma: 51.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Chemokine NA NA 617000 "Cluster 20: Non-specific - DNA binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 1 "unprognostic (2.67e-2)" "unprognostic (7.68e-3)" "prognostic favorable (2.98e-4)" "prognostic favorable (2.23e-6)" "unprognostic (8.87e-2)" "prognostic favorable (9.17e-5)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (1.34e-1)" "unprognostic (1.81e-2)" "unprognostic (1.85e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-2)" "unprognostic (7.71e-2)" "unprognostic (3.43e-2)" "unprognostic (3.12e-2)" "unprognostic (3.88e-2)" CCL23 "Ckb-8, CKb8, MIP-3, MPIF-1, SCYA23" ENSG00000274736 "C-C motif chemokine ligand 23" P55773 17 36013056-36017972 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 13.8;Endothelial cells: 93.4;Fibroblasts: 39.0;Kupffer cells: 21.7;Paneth cells: 32.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 163 "eosinophil: 184.4" "Lineage enriched" "Detected in many" 163 "granulocytes: 184.4" "Cancer enriched" "Detected in single" 50 "Leukemia: 4.9" "Liver - Sinusoid Endothelial cells" HPA042015 Uncertain "Secreted to blood" Chemokine NA NA 937000 130000 "Cluster 19: Eosinophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA042015: AB_10794039" "unprognostic (1.65e-3)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (9.50e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-1)" "unprognostic (1.20e-4)" "unprognostic (2.17e-1)" "unprognostic (6.49e-2)" "unprognostic (1.08e-2)" "unprognostic (7.05e-2)" "unprognostic (6.93e-2)" "unprognostic (1.35e-3)" "unprognostic (2.18e-1)" "unprognostic (2.76e-1)" "unprognostic (1.20e-2)" "unprognostic (1.95e-1)" CCL24 "Ckb-6, eotaxin-2, MPIF-2, MPIF2, SCYA24" ENSG00000106178 "C-C motif chemokine ligand 24" O00175 7 75810825-75823356 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 68.7;lymphoid tissue: 70.1" "Cell type enhanced" "Detected in some" "Intestinal goblet cells: 61.0;Kupffer cells: 42.4;Macrophages: 32.2;Undifferentiated cells: 16.0" "Group enriched" "Detected in many" 5 "colorectal cancer: 67.6;pancreatic cancer: 17.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "colorectal cancer: 26.1" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 4 "spinal cord: 13.6" "Secreted to blood" Chemokine NA NA 276000 "Cluster 25: Small intestine - Absorption" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 58: Macrophages - Innate immune response" 1 "unprognostic (4.55e-2)" "unprognostic (1.13e-1)" "prognostic favorable (5.41e-4)" "unprognostic (1.26e-2)" "unprognostic (1.44e-2)" "unprognostic (5.56e-2)" "unprognostic (1.73e-1)" "unprognostic (1.93e-1)" "unprognostic (4.32e-2)" "unprognostic (1.71e-1)" "unprognostic (2.35e-1)" "unprognostic (3.15e-1)" "unprognostic (2.84e-1)" "unprognostic (2.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.73e-2)" CCL25 "Ckb15, SCYA25, TECK" ENSG00000131142 "C-C motif chemokine ligand 25" O15444 19 8052318-8062660 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 1031 "intestine: 564.9;lymphoid tissue: 750.7" "Group enriched" "Detected in some" 11 "Proximal enterocytes: 941.7;Undifferentiated cells: 372.8" "Group enriched" "Detected in many" 4 "liver cancer: 25.4;stomach cancer: 33.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "NK-cell: 3.5" "Lineage enriched" "Detected in single" 5 "NK-cells: 3.5" "Cancer enhanced" "Detected in single" "breast cancer: 2.7" "Low region specificity" "Detected in all" HPA055883 Approved "Secreted to blood" Chemokine NA NA 183000000 "Cluster 24: Non-specific - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 4 "HPA055883: AB_2682955" "unprognostic (9.22e-3)" "unprognostic (3.13e-4)" "unprognostic (1.12e-1)" "unprognostic (1.29e-1)" "unprognostic (2.87e-1)" "unprognostic (9.30e-3)" "unprognostic (2.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (8.85e-3)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (2.27e-4)" "unprognostic (6.43e-2)" "unprognostic (3.86e-1)" "unprognostic (6.57e-2)" "unprognostic (2.17e-1)" CCL26 "eotaxin-3, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1" ENSG00000006606 "C-C motif chemokine ligand 26" Q9Y258 7 75769533-75789896 "Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;ovary: 19.7" "Cell type enhanced" "Detected in some" "Fibroblasts: 7.7;Leydig cells: 15.5;Ovarian stromal cells: 23.1;Sertoli cells: 5.4;Smooth muscle cells: 12.7" "Cancer enhanced" "Detected in many" "testis cancer: 14.0" "Region enriched" "Detected in some" 18 "choroid plexus: 18.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "ovarian cancer: 77.0" "Region enriched" "Detected in single" 16 "spinal cord: 3.1" "Secreted to blood" Chemokine NA NA 117000 "Cluster 8: Ciliated cells - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 48: Smooth muscle cells - Signal transduction" 6 "unprognostic (1.14e-1)" "unprognostic (4.17e-1)" "unprognostic (2.22e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (3.52e-2)" "unprognostic (2.18e-2)" "unprognostic (6.17e-2)" "unprognostic (3.02e-1)" "unprognostic (8.71e-2)" "unprognostic (7.93e-2)" "unprognostic (2.47e-1)" "unprognostic (1.05e-11)" "unprognostic (2.46e-2)" "unprognostic (1.10e-1)" "unprognostic (3.73e-1)" "unprognostic (6.29e-3)" CCL27 "ALP, CTACK, CTAK, ESkine, ILC, PESKY, SCYA27, skinkine" ENSG00000213927 "C-C motif chemokine ligand 27" Q9Y4X3 9 34661880-34664048 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 470.5" "Group enriched" "Detected in some" 22 "Basal keratinocytes: 71.3;Suprabasal keratinocytes: 97.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" HPA073848 Enhanced "Secreted to blood" Chemokine NA NA 436000 1800000 "Cluster 82: Skin - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA073848: AB_2732243" CCL28 "CCK1, MEC, SCYA28" ENSG00000151882 "C-C motif chemokine ligand 28" Q9NRJ3 5 43376645-43412391 "Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 292.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 213.3;Breast myoepithelial cells: 155.4;Mucus glandular cells: 878.9;Salivary duct cells: 321.9;Serous glandular cells: 474.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA077434 Supported "Secreted to blood" Chemokine NA NA 700000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 75: Serous glandular cells - Salivary secretion" 8 "HPA077434: AB_2732346" "unprognostic (1.04e-2)" "unprognostic (2.66e-1)" "unprognostic (8.14e-3)" "unprognostic (1.94e-2)" "unprognostic (8.85e-4)" "unprognostic (4.93e-3)" "unprognostic (1.20e-3)" "unprognostic (3.56e-2)" "unprognostic (4.91e-3)" "unprognostic (4.14e-2)" "prognostic unfavorable (1.43e-4)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (2.52e-1)" "unprognostic (1.78e-1)" "unprognostic (6.53e-2)" CCL3 "G0S19-1, LD78ALPHA, MIP-1-alpha, SCYA3" ENSG00000277632 "C-C motif chemokine ligand 3" P10147 17 36088256-36090169 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 76.2;lung: 34.7;lymphoid tissue: 48.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3179.9;Kupffer cells: 565.1;Langerhans cells: 883.9;Macrophages: 1607.3;monocytes: 1380.4;NK-cells: 543.5" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 19 "basal ganglia: 1.5;cerebral cortex: 2.7;medulla oblongata: 1.4;thalamus: 1.0;white matter: 2.7" "Immune cell enhanced" "Detected in many" "gdT-cell: 23.7" "Group enriched" "Detected in many" 4 "B-cells: 10.4;granulocytes: 10.8;T-cells: 23.7" "Cancer enriched" "Detected in some" 5 "Myeloma: 218.9" "Breast - T-cells, Liver - NK-cells (Liver), Thyroid - T-cells" "Secreted to blood" Chemokine NA NA 138000 "Cluster 14: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 58: Macrophages - Innate immune response" 3 "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.45e-1)" "unprognostic (7.44e-3)" "unprognostic (1.44e-1)" "unprognostic (1.66e-1)" "unprognostic (3.54e-1)" "unprognostic (8.90e-2)" "unprognostic (7.92e-3)" "unprognostic (2.00e-1)" "unprognostic (7.20e-2)" "unprognostic (2.05e-1)" "unprognostic (8.92e-3)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.55e-2)" "unprognostic (1.23e-2)" CCL3L1 "CCL3L3, D17S1718, G0S19-2, LD78BETA, MGC12815, SCYA3L, SCYA3L1" ENSG00000276085 "C-C motif chemokine ligand 3 like 1" P16619 17 36194869-36196758 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.0;lung: 4.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 796.8;Kupffer cells: 154.6;Langerhans cells: 385.1;Macrophages: 500.2;monocytes: 206.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "eosinophil: 4.2;neutrophil: 1.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Group enriched" "Detected in some" 11 "lymphoma: 2.3;Myeloma: 9.1" "Secreted to blood" Chemokine NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Myeloma - Immune response" "Cluster 58: Macrophages - Innate immune response" 4 "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "unprognostic (5.37e-2)" "unprognostic (1.46e-1)" "unprognostic (9.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.36e-2)" "unprognostic (3.69e-1)" "unprognostic (5.75e-2)" "unprognostic (5.55e-2)" "unprognostic (2.40e-2)" "unprognostic (3.66e-1)" "unprognostic (9.08e-2)" "unprognostic (2.09e-1)" "unprognostic (3.21e-1)" "unprognostic (1.90e-2)" "unprognostic (8.58e-2)" CCL4 "Act-2, AT744.1, LAG1, MIP-1-beta, SCYA4" ENSG00000275302 "C-C motif chemokine ligand 4" P13236 17 36103827-36105621 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 190.3" "Group enriched" "Detected in many" 4 "Hofbauer cells: 1392.3;Macrophages: 1352.6;monocytes: 2638.6;NK-cells: 4652.8;T-cells: 2183.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 416.0" "Group enriched" "Detected in all" 6 "granulocytes: 135.5;T-cells: 416.0" "Cancer enriched" "Detected in some" 4 "lymphoma: 51.1" "Adipose subcutaneous - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in single" CAB007805 Approved "Secreted to blood" Chemokine NA NA 144000 "Cluster 24: Non-specific - Transcription" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 19: NK-cells - Adaptive immune response" 16 "CAB007805: AB_598177" "unprognostic (6.03e-2)" "unprognostic (2.48e-2)" "prognostic favorable (3.54e-4)" "prognostic favorable (1.97e-5)" "unprognostic (2.06e-1)" "unprognostic (7.02e-2)" "unprognostic (9.08e-2)" "unprognostic (2.69e-1)" "prognostic favorable (3.97e-4)" "unprognostic (3.45e-1)" "unprognostic (8.57e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (3.71e-1)" "unprognostic (1.30e-1)" "unprognostic (1.18e-1)" "unprognostic (1.18e-2)" CCL4L2 ENSG00000276070 "C-C motif chemokine ligand 4 like 2" Q8NHW4 17 36210924-36212878 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.7;lymphoid tissue: 20.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 817.2;Langerhans cells: 424.1;Macrophages: 541.1;monocytes: 367.7;NK-cells: 638.3;T-cells: 276.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 7 "eosinophil: 122.3" "Lineage enriched" "Detected in many" 8 "granulocytes: 122.3" "Cancer enriched" "Detected in some" 8 "lymphoma: 13.4" "Breast - T-cells, Thyroid - T-cells" "Secreted to blood" Chemokine NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 58: Macrophages - Innate immune response" 31 "unprognostic (1.79e-1)" "unprognostic (1.17e-1)" "unprognostic (2.46e-2)" "unprognostic (1.44e-2)" "unprognostic (1.16e-1)" "unprognostic (6.07e-2)" "unprognostic (3.82e-1)" "unprognostic (3.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.14e-1)" "unprognostic (3.62e-2)" "unprognostic (1.93e-1)" "unprognostic (1.27e-2)" "unprognostic (2.27e-1)" "unprognostic (2.08e-1)" "unprognostic (8.51e-2)" "unprognostic (1.99e-3)" CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.9;lymphoid tissue: 131.6" "Group enriched" "Detected in many" 10 "NK-cells: 2703.3;T-cells: 2071.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6781.0;memory CD8 T-cell: 7136.0" "Group enriched" "Detected in all" 7 "NK-cells: 2043.0;T-cells: 7136.0" "Cancer enhanced" "Detected in many" "Leukemia: 57.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" CAB078447 Enhanced "Secreted to blood" Chemokine NA NA 20100000 2900000 "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" 25 "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" CCL7 "FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7" ENSG00000108688 "C-C motif chemokine ligand 7" P80098 17 34270221-34272242 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "bone marrow: 25.6" "Cell type enhanced" "Detected in some" "Ductal cells: 7.0;Hofbauer cells: 50.1;Macrophages: 14.9;Mesothelial cells: 25.7;Secretory cells: 20.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 6 "thalamus: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Chemokine NA NA 29700 "Cluster 6: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 2 "unprognostic (7.66e-2)" "unprognostic (1.05e-2)" "unprognostic (8.53e-2)" "unprognostic (4.65e-2)" "unprognostic (2.54e-2)" "unprognostic (9.54e-2)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (2.63e-2)" "unprognostic (2.27e-3)" "unprognostic (7.04e-2)" "unprognostic (1.99e-8)" "unprognostic (2.83e-1)" "unprognostic (8.74e-2)" "unprognostic (3.74e-1)" "unprognostic (1.79e-2)" CCL8 "HC14, MCP-2, SCYA8" ENSG00000108700 "C-C motif chemokine ligand 8" P80075 17 34319435-34321402 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 22.3;Early spermatids: 14.7;Fibroblasts: 13.4;Macrophages: 42.1;Smooth muscle cells: 98.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "spinal cord: 2.9;thalamus: 1.6" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 6 "monocytes: 3.4" "Not detected" "Not detected" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in many" "Secreted to blood" Chemokine NA NA 32000 "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "unprognostic (7.51e-2)" "unprognostic (3.20e-1)" "unprognostic (1.90e-2)" "unprognostic (4.03e-2)" "unprognostic (8.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.52e-1)" "unprognostic (1.65e-1)" "unprognostic (9.97e-2)" "unprognostic (1.67e-3)" "unprognostic (1.46e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.05e-7)" "unprognostic (1.39e-1)" "unprognostic (1.88e-2)" "unprognostic (5.65e-2)" "unprognostic (3.41e-2)" CCN1 "CYR61, GIG1, IGFBP10" ENSG00000142871 "Cellular communication network factor 1" O00622 1 85580761-85584589 "Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 749.5;Fibroblasts: 865.9;Glandular and luminal cells: 762.3;Granulosa cells: 766.1;Ionocytes: 776.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029853 Uncertain "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Respiratory epithelial cells - Unknown function" 2 "HPA029853: AB_10611822" "unprognostic (6.09e-2)" "unprognostic (3.25e-2)" "unprognostic (9.97e-2)" "unprognostic (8.90e-2)" "unprognostic (1.80e-2)" "unprognostic (3.91e-2)" "unprognostic (3.47e-2)" "unprognostic (1.56e-2)" "unprognostic (2.59e-1)" "unprognostic (9.95e-2)" "unprognostic (1.35e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.04e-3)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (3.74e-3)" CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 401.7;Endothelial cells: 429.4;Fibroblasts: 571.8;Glandular and luminal cells: 402.3;Pancreatic endocrine cells: 438.1;Peritubular cells: 471.5;Smooth muscle cells: 459.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005123, HPA031074, HPA031075" Approved Supported "Golgi apparatus" "Secreted in other tissues" "Cell adhesion" No No 1010000 5900000 "Cluster 34: B-cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 3 "Golgi apparatus" "CAB005123: AB_638805, HPA031074: AB_10599618, HPA031075: AB_10611248" "unprognostic (2.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (5.68e-2)" "unprognostic (9.79e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (4.96e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.27e-3)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (3.84e-3)" CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1072.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 45.1;Glandular and luminal cells: 68.4;granulocytes: 82.3;Melanocytes: 115.1;Smooth muscle cells: 72.1" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.9;neutrophil: 30.9" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.9" "Cancer enhanced" "Detected in many" "lung cancer: 42.6;skin cancer: 67.9" "Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Thyroid - Fibroblasts" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.1" "Region enriched" "Detected in all" 6 "spinal cord: 161.3" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" "Growth factor" NA NA 269000000 2800000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 32: Smooth muscle cells - Muscle contraction" 12 Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" CCN4 "WISP-1, WISP1, WISP1-OT1, WISP1-UT1" ENSG00000104415 "Cellular communication network factor 4" O95388 8 133191039-133231690 "Cancer-related genes, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 19.3" "Cell type enhanced" "Detected in some" "Fibroblasts: 15.5;Lymphatic endothelial cells: 3.7;Ovarian stromal cells: 3.7;Smooth muscle cells: 4.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain cancer: 22.9;thyroid cancer: 12.5" "Region enriched" "Detected in some" 6 "olfactory bulb: 9.8" "Region enhanced" "Detected in some" "spinal cord: 6.2" "HPA007121, CAB012205" Uncertain Uncertain Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 9: Endometrial stromal cells - Transcription" 1 Cytosol "CAB012205: , HPA007121: AB_1858844" "unprognostic (7.77e-2)" "unprognostic (2.05e-1)" "unprognostic (3.30e-2)" "unprognostic (3.20e-1)" "unprognostic (7.72e-2)" "unprognostic (6.63e-2)" "unprognostic (8.61e-3)" "unprognostic (3.26e-2)" "unprognostic (2.07e-3)" "unprognostic (1.41e-3)" "unprognostic (3.01e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (7.52e-3)" "unprognostic (2.55e-3)" "unprognostic (6.03e-2)" "unprognostic (5.67e-3)" CCN5 "CT58, CTGF-L, WISP-2, WISP2" ENSG00000064205 "Cellular communication network factor 5" O76076 20 44714844-44728509 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 381.7;cervix: 343.8" "Group enriched" "Detected in many" 5 "Fibroblasts: 403.1;Leydig cells: 398.3;Ovarian stromal cells: 184.6;Schwann cells: 197.1;Smooth muscle cells: 135.2" "Cancer enhanced" "Detected in many" "melanoma: 8.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Adrenocortical cancer: 64.4;cervical cancer: 37.8;Kidney cancer: 22.6;liver cancer: 46.7;Sarcoma: 34.3" "Adipose subcutaneous - Adipose progenitor cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB019273, HPA072121" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 1200000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "CAB019273: , HPA072121: " "unprognostic (1.87e-1)" "unprognostic (2.64e-1)" "unprognostic (3.01e-2)" "unprognostic (1.12e-1)" "unprognostic (1.70e-1)" "unprognostic (2.83e-1)" "unprognostic (1.83e-1)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (9.42e-2)" "unprognostic (2.81e-1)" "unprognostic (7.95e-3)" "unprognostic (1.76e-10)" "unprognostic (1.55e-3)" "unprognostic (7.21e-2)" "unprognostic (4.84e-2)" "unprognostic (1.28e-1)" CCN6 "WISP-3, WISP3" ENSG00000112761 "Cellular communication network factor 6" O95389 6 112054075-112069686 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.1;epididymis: 9.9" "Group enriched" "Detected in some" 7 "Early spermatids: 66.1;Late spermatids: 33.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.9" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA064196 Supported Mitochondria "Secreted to extracellular matrix" "Growth factor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Early spermatids - Spermatogenesis" Mitochondria "HPA064196: AB_2685209" "unprognostic (2.13e-2)" "unprognostic (7.90e-3)" "unprognostic (5.00e-2)" "unprognostic (2.22e-2)" "unprognostic (3.76e-1)" "unprognostic (6.52e-2)" "unprognostic (1.98e-3)" "unprognostic (4.07e-3)" "unprognostic (1.82e-1)" "unprognostic (3.90e-1)" "unprognostic (1.02e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "unprognostic (3.11e-1)" "unprognostic (4.91e-2)" "unprognostic (2.93e-2)" CCNL1 ania-6a ENSG00000163660 "Cyclin L1" Q9UK58 3 157146508-157160760 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Cyclin Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 891.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057911 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Transcription NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 80: Non-specific - Transcription" 16 "Nucleoplasm, Nuclear bodies" "HPA057911: AB_2683553" "unprognostic (1.03e-2)" "unprognostic (3.66e-2)" "unprognostic (1.38e-1)" "unprognostic (6.90e-3)" "unprognostic (1.79e-1)" "unprognostic (6.58e-2)" "unprognostic (3.16e-3)" "unprognostic (7.50e-2)" "unprognostic (5.54e-3)" "unprognostic (3.37e-1)" "unprognostic (3.06e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.01e-6)" "unprognostic (3.71e-1)" "unprognostic (2.24e-1)" "unprognostic (5.62e-2)" "prognostic favorable (6.96e-7)" CCNL2 "ania-6b, CCNM, CCNS, HLA-ISO, PCEE, SB138" ENSG00000221978 "Cyclin L2" Q96S94 1 1385711-1399335 "Predicted intracellular proteins" "Transcription, Transcription regulation" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053137 Supported Supported Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 55: Non-specific - Transcription" 1 Nucleoplasm "HPA053137: AB_2682053" "unprognostic (3.08e-2)" "unprognostic (2.60e-1)" "unprognostic (1.14e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "unprognostic (1.59e-3)" "unprognostic (2.06e-1)" "unprognostic (3.91e-2)" "unprognostic (1.67e-2)" "unprognostic (1.15e-1)" "unprognostic (7.08e-3)" "unprognostic (2.91e-2)" "prognostic unfavorable (1.12e-6)" "unprognostic (4.61e-2)" "unprognostic (6.17e-2)" "unprognostic (3.71e-1)" "prognostic favorable (1.46e-7)" CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633700 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 347.3" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2936.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3500.8" "Group enriched" "Detected in all" 6 "granulocytes: 935.1;monocytes: 3500.8" "Cancer enhanced" "Detected in many" "breast cancer: 11.9;head and neck cancer: 9.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Hepatocytes, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" Immunity NA NA 2750000000 10000000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Liver - Plasma proteins" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" CD160 "BY55, NK1, NK28" ENSG00000117281 "CD160 molecule" O95971 1 145719471-145739288 "CD markers, Predicted secreted proteins" "Adaptive immunity, Angiogenesis, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 5.1;brain: 14.5;intestine: 4.5;liver: 4.9;lymphoid tissue: 13.1" "Cell type enriched" "Detected in some" 4 "NK-cells: 216.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 108.0;MAIT T-cell: 44.6;memory CD8 T-cell: 73.0;naive CD8 T-cell: 83.2;NK-cell: 86.1" "Group enriched" "Detected in all" 8 "NK-cells: 86.1;T-cells: 108.0" "Low cancer specificity" "Detected in many" "Liver - NK-cells (Liver)" "Not detected" "Not detected" "Secreted to blood" Receptor NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 6 "unprognostic (6.54e-4)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.33e-1)" "unprognostic (3.40e-2)" "unprognostic (1.35e-1)" "unprognostic (8.25e-3)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (2.24e-2)" "unprognostic (7.49e-3)" "unprognostic (3.48e-5)" "unprognostic (4.05e-2)" "unprognostic (2.03e-1)" "unprognostic (2.89e-2)" "unprognostic (2.92e-4)" CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 234.7" "Group enriched" "Detected in many" 4 "Kupffer cells: 1630.5;Macrophages: 624.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 112.0" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.3" "Group enriched" "Detected in many" 40 "dendritic cells: 65.3;monocytes: 76.1" "Cancer enriched" "Detected in single" 9 "lymphoma: 6.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" "Acute phase" NA NA 903000000 1600000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 57: Lung - Lung function" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 58: Macrophages - Innate immune response" 1 "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" CD163L1 "CD163B, M160, SCARI2, WC1" ENSG00000177675 "CD163 molecule like 1" Q9NR16 12 7346685-7479897 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3;lymphoid tissue: 31.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 28.5;Breast myoepithelial cells: 17.9;Excitatory neurons: 18.2;Inhibitory neurons: 15.9;Lymphatic endothelial cells: 13.8;Melanocytes: 24.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Macrophages, Testis - Early spermatids" HPA015663 Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Intracellular and membrane" "No annotated function" NA NA 660000 "Cluster 25: Small intestine - Absorption" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 17: Breast glandular cells - Lactation" "Centrosome, Cytosol" Nucleoplasm "HPA015663: AB_2072575" "unprognostic (1.25e-3)" "unprognostic (1.77e-1)" "unprognostic (1.42e-2)" "unprognostic (7.46e-3)" "unprognostic (2.29e-2)" "unprognostic (7.79e-2)" "unprognostic (9.39e-2)" "unprognostic (4.44e-3)" "unprognostic (1.07e-1)" "unprognostic (8.35e-2)" "unprognostic (1.08e-1)" "unprognostic (3.08e-1)" "unprognostic (1.26e-6)" "unprognostic (8.59e-2)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.69e-1)" CD164 "DFNA66, MGC-24, MUC-24" ENSG00000135535 "CD164 molecule" Q04900 6 109366514-109382467 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 751.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010636 Approved "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 3 "HPA010636: AB_1078447" "unprognostic (1.23e-2)" "unprognostic (1.61e-2)" "unprognostic (3.89e-2)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-2)" "unprognostic (1.97e-3)" "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (8.88e-2)" "unprognostic (1.38e-1)" "unprognostic (7.11e-2)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "unprognostic (3.01e-1)" "unprognostic (1.51e-1)" CD177 "HNA2A, NB1, PRV1" ENSG00000204936 "CD177 molecule" 19 43353686-43363172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 283.3;intestine: 159.6" "Cell type enriched" "Detected in some" 5 "Distal enterocytes: 357.0" "Cancer enhanced" "Detected in many" "prostate cancer: 27.6" "Region enhanced" "Detected in many" "cerebral cortex: 17.6" "Immune cell enriched" "Detected in some" 7 "neutrophil: 8.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.8" "Cancer enriched" "Detected in many" 20 "Rhabdoid: 55.5" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Prostate - Prostate glandular cells, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041820, HPA046601, HPA077640" Enhanced "Intracellular and membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 5: Enterocytes - Absorption" "HPA041820: AB_2677691, HPA046601: AB_2679716, HPA077640: " "unprognostic (4.32e-2)" "prognostic favorable (3.66e-4)" "unprognostic (1.04e-2)" "unprognostic (2.04e-3)" "unprognostic (1.61e-1)" "unprognostic (3.89e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (2.05e-1)" "unprognostic (1.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.90e-2)" "unprognostic (2.45e-1)" "unprognostic (2.70e-1)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (1.24e-1)" CD1E ENSG00000158488 "CD1e molecule" P15812 1 158353696-158357553 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 69 "lymphoid tissue: 937.7" "Cell type enriched" "Detected in some" 19 "Langerhans cells: 750.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 14 "myeloid DC: 62.6" "Lineage enriched" "Detected in many" 14 "dendritic cells: 62.6" "Cancer enriched" "Detected in single" 433 "Leukemia: 66.8" "Skin - Langerhans cells" "Not detected" "Not detected" "HPA057769, HPA070634" Uncertain Supported "Nucleoli,Golgi apparatus" "Intracellular and membrane" Immunity NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 28: Dendritic cells - Antigen presentation" "Golgi apparatus" Nucleoli "HPA057769: AB_2683522, HPA070634: " "unprognostic (7.94e-3)" "unprognostic (1.85e-5)" "unprognostic (1.47e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.33e-1)" "unprognostic (1.54e-3)" "unprognostic (1.24e-1)" "unprognostic (1.74e-1)" "unprognostic (1.60e-1)" "unprognostic (8.55e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (2.49e-1)" "unprognostic (8.50e-2)" "unprognostic (2.45e-1)" CD200R1 "CD200R, HCRTR2, MOX2R, OX2R" ENSG00000163606 "CD200 receptor 1" Q8TD46 3 112921205-112975103 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.7" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.6;granulocytes: 24.1;Hofbauer cells: 29.6;Langerhans cells: 23.3;Macrophages: 9.0;T-cells: 12.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 4 "basophil: 235.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 235.9" "Cancer enhanced" "Detected in some" "cervical cancer: 10.0" HPA068512 Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 2000000 "Cluster 46: Basophils - Proteolysis" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "HPA068512: AB_2732784" "unprognostic (1.49e-2)" "unprognostic (1.06e-2)" "unprognostic (2.55e-1)" "unprognostic (1.97e-2)" "unprognostic (1.53e-1)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-3)" "unprognostic (8.30e-2)" "unprognostic (1.85e-1)" "unprognostic (7.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.77e-1)" "unprognostic (7.84e-3)" "unprognostic (1.25e-1)" "unprognostic (5.12e-3)" CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1, hDC-SIGN" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.0;placenta: 22.0" "Group enriched" "Detected in some" 4 "Kupffer cells: 12.9;Langerhans cells: 14.9;Macrophages: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 5 "dendritic cells: 1.2;monocytes: 1.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Thyroid - Macrophages" "CAB032436, CAB033831" Supported "Intracellular and membrane" Receptor NA NA 3100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 57: Lung - Lung function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 1 "CAB032436: AB_639039, CAB033831: AB_1121347" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.36e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (3.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (6.17e-2)" "unprognostic (1.09e-1)" CD24 CD24A ENSG00000272398 "CD24 molecule" P25063 6 106969831-106975627 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 1581.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2800.6;Exocrine glandular cells: 2217.6;Glandular and luminal cells: 1467.2;Suprabasal keratinocytes: 1440.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 29 "eosinophil: 86.4;memory B-cell: 61.3;naive B-cell: 39.9" "Group enriched" "Detected in many" 240 "B-cells: 61.3;granulocytes: 86.4" "Cancer enhanced" "Detected in all" "breast cancer: 1239.9" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 159.0" "HPA045879, CAB078471" Approved Enhanced Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 29: Forebrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 Vesicles "CAB078471: AB_10983158, HPA045879: AB_2732523" "prognostic unfavorable (2.44e-5)" "unprognostic (6.64e-2)" "prognostic favorable (3.29e-4)" "unprognostic (1.87e-1)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (7.58e-4)" "unprognostic (2.32e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (2.28e-2)" "unprognostic (1.51e-1)" "unprognostic (5.10e-2)" "unprognostic (2.92e-1)" "unprognostic (1.16e-1)" "unprognostic (2.01e-1)" "unprognostic (3.13e-1)" CD300A "CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60" ENSG00000167851 "CD300a molecule" Q9UGN4 17 74466399-74484794 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 92.9" "Cell type enhanced" "Detected in some" "dendritic cells: 55.9;Hofbauer cells: 135.8;Kupffer cells: 95.5;Macrophages: 76.0;monocytes: 132.3;NK-cells: 138.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 59.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 40.9;Myeloma: 12.0" "Liver - Kupffer cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - T-cells" "HPA010971, HPA011645" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Monocytes - Innate immune response" 6 "Plasma membrane" "Vesicles, Cytosol" "HPA010971: , HPA011645: AB_1846988" "unprognostic (1.99e-1)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.01e-1)" "unprognostic (1.04e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (5.97e-2)" "unprognostic (5.45e-3)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" CD300H ENSG00000284690 "CD300H molecule (gene/pseudogene)" A0A0K2S4Q6 17 74560701-74567343 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.6;lymphoid tissue: 7.5" "Group enriched" "Detected in some" 5 "Macrophages: 3.1;monocytes: 8.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 9 "intermediate monocyte: 655.3;non-classical monocyte: 1135.8" "Lineage enriched" "Detected in all" 12 "monocytes: 1135.8" "Cancer enriched" "Detected in single" 7 "lymphoma: 2.1" "Low region specificity" "Detected in all" "Secreted to blood" "No annotated function" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" CD40 "Bp50, p50, TNFRSF5" ENSG00000101017 "CD40 molecule" P25942 20 46118271-46129863 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 126.2;Basal respiratory cells: 118.9;Langerhans cells: 237.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 108.3;naive B-cell: 123.7" "Group enriched" "Detected in all" 6 "B-cells: 123.7;monocytes: 34.9" "Cancer enhanced" "Detected in many" "lymphoma: 97.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002495, HPA031567, HPA031568, CAB072868" Enhanced "Secreted to blood" Receptor NA NA 705000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 18 "CAB002495: AB_563562, CAB072868: AB_2665719, HPA031567: AB_2673936, HPA031568: AB_2673937" "unprognostic (6.41e-2)" "unprognostic (1.55e-2)" "unprognostic (7.08e-3)" "unprognostic (6.21e-2)" "unprognostic (4.23e-3)" "unprognostic (1.25e-1)" "unprognostic (7.64e-3)" "unprognostic (1.34e-1)" "unprognostic (4.15e-2)" "unprognostic (7.16e-2)" "unprognostic (2.48e-2)" "unprognostic (7.04e-2)" "prognostic unfavorable (4.48e-4)" "unprognostic (1.22e-1)" "unprognostic (4.95e-2)" "unprognostic (1.60e-2)" "unprognostic (2.28e-2)" CD40LG "CD154, CD40-L, CD40L, gp39, hCD40L, HIGM1, IMD3, T-BAM, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 3.7;lymphoid tissue: 14.7" "Cell type enriched" "Detected in some" 9 "T-cells: 78.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "gdT-cell: 26.4;MAIT T-cell: 64.4;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.3" "Lineage enriched" "Detected in many" 34 "T-cells: 80.5" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Skin - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" Cytokine NA NA 776000 20000 "Cluster 11: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 484.4" "Cell type enhanced" "Detected in many" "Ductal cells: 983.9;Exocrine glandular cells: 928.7;granulocytes: 1083.6;Langerhans cells: 2343.8;monocytes: 1059.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1400.7" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" Receptor NA NA 1200000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Stomach - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 29: Monocytes - Innate immune response" 3 "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 146.6;lymphoid tissue: 277.0" "Cell type enhanced" "Detected in many" "B-cells: 357.1;granulocytes: 236.4;Hofbauer cells: 222.8;Kupffer cells: 212.1;Macrophages: 183.5;monocytes: 953.3;NK-cells: 402.1;Schwann cells: 198.4;T-cells: 432.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 243.2;Myeloma: 458.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Secreted to blood" "No annotated function" NA NA 2000000 "Cluster 33: Non-specific - ATP binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 19: NK-cells - Adaptive immune response" 1 "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" CD55 "CR, CROM, DAF, TC" ENSG00000196352 "CD55 molecule (Cromer blood group)" P08174 1 207321519-207386804 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1446.0;monocytes: 1765.3;Syncytiotrophoblasts: 871.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 653.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA002190, CAB010454, HPA024386" Enhanced "Secreted to blood" "Complement pathway" NA No 32300000 360000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" "CAB010454: AB_2075970, HPA002190: AB_1078472, HPA024386: AB_1846319" "unprognostic (4.08e-2)" "unprognostic (3.22e-1)" "unprognostic (3.41e-1)" "unprognostic (1.63e-1)" "unprognostic (9.05e-2)" "unprognostic (1.08e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-2)" "unprognostic (1.55e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (3.41e-2)" "unprognostic (2.04e-1)" "unprognostic (9.70e-2)" "unprognostic (2.33e-2)" CD59 "16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20" ENSG00000085063 "CD59 molecule (CD59 blood group)" P13987 11 33703010-33736479 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1341.1;Melanocytes: 1613.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001448, HPA026494" Supported Uncertain "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 58000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 3 "Golgi apparatus, Vesicles" "CAB001448: AB_563604, HPA026494: AB_1846321" "unprognostic (2.07e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (7.40e-2)" "unprognostic (1.14e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (4.47e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (1.66e-2)" "prognostic favorable (1.39e-10)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (3.09e-1)" CD5L "API6, Spalpha" ENSG00000073754 "CD5 molecule like" O43866 1 157830911-157898256 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 558.4" "Group enriched" "Detected in some" 29 "Hofbauer cells: 226.6;Kupffer cells: 624.6" "Cancer enriched" "Detected in some" 5 "liver cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Kupffer cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065686, HPA068384" Enhanced "Secreted to blood" Immunity NA NA 4030000000 4300000000 "Cluster 47: Spleen - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" "HPA065686: AB_2685532, HPA068384: AB_2685979" "unprognostic (2.96e-1)" "unprognostic (2.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "prognostic favorable (8.88e-5)" "unprognostic (1.73e-2)" "unprognostic (4.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.56e-1)" "unprognostic (5.95e-3)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" "unprognostic (3.63e-1)" CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.2;lymphoid tissue: 42.2" "Group enriched" "Detected in some" 8 "NK-cells: 40.2;T-cells: 99.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 33 "gdT-cell: 27.8;MAIT T-cell: 24.7;memory CD4 T-cell: 51.5;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.5;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 50 "T-cells: 51.5" "Group enriched" "Detected in some" 10 "Leukemia: 10.8;lymphoma: 11.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" Immunity NA NA 5270000 160000 "Cluster 11: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 5 "CAB002489: AB_563605, CAB016252: AB_631163" "prognostic favorable (1.95e-4)" "prognostic favorable (1.57e-5)" "unprognostic (4.47e-2)" "prognostic favorable (2.41e-4)" "unprognostic (2.06e-2)" "prognostic favorable (5.10e-6)" "unprognostic (8.45e-3)" "unprognostic (8.21e-3)" "unprognostic (2.87e-3)" "unprognostic (5.32e-3)" "unprognostic (2.07e-1)" "unprognostic (5.35e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "unprognostic (6.19e-2)" "unprognostic (5.96e-2)" CD63 "ME491, MLA1, TSPAN30" ENSG00000135404 "CD63 molecule" P08962 12 55725323-55729707 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1861.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010088, CAB026356, HPA073506" Supported Supported Vesicles "Intracellular and membrane" Transport NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 45: Non-specific - Mixed function" 3 Vesicles "CAB026356: AB_629864, HPA010088: AB_1846323, HPA073506: " "unprognostic (8.76e-3)" "unprognostic (8.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.28e-3)" "unprognostic (9.48e-2)" "unprognostic (3.66e-3)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.11e-1)" "unprognostic (6.50e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-2)" "unprognostic (3.10e-1)" "unprognostic (2.70e-2)" "unprognostic (4.82e-2)" "unprognostic (5.21e-2)" "unprognostic (1.85e-3)" "unprognostic (9.02e-2)" CD80 "B7-1, B7.1, CD28LG, CD28LG1" ENSG00000121594 "CD80 molecule" P33681 3 119524293-119559614 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 2.9;lymphoid tissue: 6.6" "Group enriched" "Detected in some" 4 "B-cells: 9.1;Langerhans cells: 21.3;Macrophages: 7.2;monocytes: 19.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;T-reg: 1.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "lymphoma: 19.6" "Liver - Kupffer cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB025368, HPA050092" Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 3 "CAB025368: , HPA050092: AB_2681012" "unprognostic (2.36e-1)" "unprognostic (1.55e-2)" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (3.14e-1)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (4.14e-3)" "unprognostic (1.02e-2)" "unprognostic (4.96e-3)" "unprognostic (1.16e-2)" "unprognostic (1.15e-1)" "unprognostic (9.03e-8)" "unprognostic (3.20e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (1.94e-2)" CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 226.2" "Cell type enriched" "Detected in many" 4 "T-cells: 243.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 227.9;memory CD8 T-cell: 509.4;naive CD8 T-cell: 461.5" "Lineage enriched" "Detected in many" 19 "T-cells: 509.4" "Group enriched" "Detected in some" 9 "Leukemia: 4.0;lymphoma: 5.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA 490000 "Cluster 11: T-cells - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 1 "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 447.5" "Cell type enriched" "Detected in many" 11 "T-cells: 159.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 602.5;naive CD8 T-cell: 1058.1" "Lineage enriched" "Detected in all" 25 "T-cells: 1058.1" "Group enriched" "Detected in some" 9 "Leukemia: 8.7;Myeloma: 33.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" CD9 "BA2, MIC3, MRP-1, P24, TSPAN29" ENSG00000010278 "CD9 molecule" P21926 12 6199715-6238271 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2694.8;Ionocytes: 2140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 26 "basophil: 1961.8;eosinophil: 1159.2" "Lineage enriched" "Detected in all" 32 "granulocytes: 1961.8" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002490 Supported Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 1200000 "Cluster 41: Basophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 11: White matter - Signal transduction" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Plasma membrane" "CAB002490: AB_563643" "unprognostic (1.38e-1)" "unprognostic (6.36e-3)" "unprognostic (8.27e-3)" "unprognostic (6.98e-3)" "unprognostic (3.89e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (2.90e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (6.10e-2)" "unprognostic (1.77e-1)" "prognostic favorable (8.93e-5)" "unprognostic (9.26e-2)" CDC23 "ANAPC8, APC8, CUT23" ENSG00000094880 "Cell division cycle 23" Q9UJX2 5 138187650-138213343 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039593 Approved "Intracellular and membrane" Other NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" 69 "HPA039593: AB_10795146" "unprognostic (5.45e-2)" "unprognostic (1.83e-1)" "unprognostic (5.26e-3)" "unprognostic (3.46e-2)" "unprognostic (8.46e-2)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.37e-1)" "unprognostic (2.85e-1)" "unprognostic (3.12e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-1)" "unprognostic (9.68e-3)" "unprognostic (9.30e-2)" "unprognostic (1.02e-1)" "unprognostic (3.12e-2)" "unprognostic (3.46e-1)" CDC40 "EHB3, FLJ10564, PRP17, PRPF17" ENSG00000168438 "Cell division cycle 40" O60508 6 110180141-110254275 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 275.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046620 Supported Nucleoplasm "Intracellular and membrane" Other NA NA "Cluster 32: Basophils - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 21: Early spermatids - Spermatogenesis" 1 Nucleoplasm "HPA046620: AB_2679722" "unprognostic (4.19e-3)" "unprognostic (2.41e-2)" "unprognostic (1.23e-2)" "unprognostic (1.10e-2)" "unprognostic (4.25e-2)" "unprognostic (3.64e-2)" "unprognostic (3.42e-2)" "unprognostic (5.24e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (9.27e-2)" "unprognostic (1.92e-1)" "unprognostic (4.68e-2)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (3.01e-1)" "unprognostic (2.09e-1)" CDCP1 "CD318, SIMA135" ENSG00000163814 "CUB domain containing protein 1" Q9H5V8 3 45082277-45146422 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 111.9;Basal respiratory cells: 87.9;Suprabasal keratinocytes: 73.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 26.9" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.3;NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Heart muscle - Macrophages, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010978, HPA010979, CAB025637" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "CAB025637: , HPA010978: AB_1846403, HPA010979: AB_1846401" "unprognostic (9.31e-2)" "unprognostic (4.50e-2)" "unprognostic (1.67e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (1.41e-5)" "unprognostic (2.15e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (9.98e-3)" "unprognostic (3.59e-2)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" CDCP2 ENSG00000157211 "CUB domain containing protein 2" Q5VXM1 1 54132687-54153770 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031143 Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 11: Neuronal - Sensory perception" "HPA031143: AB_10611819" "unprognostic (1.08e-1)" "unprognostic (5.16e-2)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-2)" "unprognostic (4.73e-2)" "unprognostic (5.29e-2)" "unprognostic (2.86e-2)" "unprognostic (2.57e-1)" "unprognostic (1.33e-1)" "unprognostic (1.67e-2)" "unprognostic (7.67e-6)" "unprognostic (2.37e-1)" "unprognostic (1.48e-1)" "unprognostic (5.12e-1)" "unprognostic (2.21e-2)" CDH13 CDHH ENSG00000140945 "Cadherin 13" P55290 16 82626965-83800640 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 55.1;skeletal muscle: 66.1;tongue: 55.5" "Group enriched" "Detected in many" 4 "Excitatory neurons: 316.9;Inhibitory neurons: 827.4;Oligodendrocyte precursor cells: 315.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.3" "Group enriched" "Detected in many" 5 "granulocytes: 1.4;monocytes: 4.3" "Cancer enhanced" "Detected in many" "Brain cancer: 66.5;testis cancer: 95.3" "Adipose visceral - Endothelial cells, Lung - Fibroblast_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001380, CAB025863" Enhanced Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 240000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Neurons - Synaptic function" 2 "Plasma membrane" "CAB025863: , HPA001380: AB_1078371" "unprognostic (2.50e-2)" "unprognostic (2.75e-2)" "unprognostic (5.61e-2)" "unprognostic (4.06e-1)" "unprognostic (4.88e-2)" "unprognostic (3.30e-3)" "unprognostic (3.01e-1)" "unprognostic (5.76e-2)" "unprognostic (3.49e-2)" "unprognostic (3.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.73e-6)" "unprognostic (5.16e-3)" "unprognostic (2.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" CDH18 "CDH14, EY-CADHERIN" ENSG00000145526 "Cadherin 18" Q13634 5 19471296-20575873 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 4.5;brain: 15.4;pituitary gland: 3.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 893.6;Inhibitory neurons: 667.7;Oligodendrocyte precursor cells: 233.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014416 Uncertain "Intracellular and membrane" "Cell adhesion" NA Yes "Cluster 22: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 8: Neurons - Neuronal signaling" "HPA014416: AB_2668996" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "unprognostic (5.26e-7)" "unprognostic (6.36e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (8.78e-2)" "unprognostic (3.30e-2)" "unprognostic (1.51e-2)" "unprognostic (8.69e-2)" "unprognostic (1.76e-2)" CDHR1 "CORD15, KIAA1775, PCDH21, RP65" ENSG00000148600 "Cadherin related family member 1" Q96JP9 10 84194537-84219621 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 304.3;skin 1: 208.5" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 360.2;Rod photoreceptor cells: 214.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "NK-cell: 7.5" "Lineage enriched" "Detected in single" 12 "NK-cells: 7.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.9" "Adipose visceral - T-cells, Colon - Colon enterocytes, Liver - NK-cells (Liver), Skin - Keratinocyte (other), Stomach - Fibroblasts, Thyroid - T-cells" "Region enriched" "Detected in many" 21 "olfactory bulb: 333.1" "Low region specificity" "Detected in all" "HPA010795, HPA036819" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Receptor NA NA 55000 "Cluster 15: NK-cells - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "Golgi apparatus" "HPA010795: , HPA036819: AB_10671750" "unprognostic (8.91e-4)" "unprognostic (5.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.71e-2)" "unprognostic (2.63e-2)" "unprognostic (3.03e-2)" "unprognostic (6.40e-2)" "unprognostic (7.77e-2)" "unprognostic (1.41e-1)" "unprognostic (2.67e-1)" "unprognostic (6.69e-4)" "unprognostic (1.90e-1)" "unprognostic (5.51e-3)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (4.56e-3)" "unprognostic (5.07e-2)" CDHR4 "CDH29, VLLR9392" ENSG00000187492 "Cadherin related family member 4" A6H8M9 3 49790732-49799873 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "fallopian tube: 57.4" "Cell type enriched" "Detected in some" 16 "Ciliated cells: 107.6" "Cancer enriched" "Detected in some" 6 "endometrial cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.0" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA076277 Enhanced "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 59: Fallopian tube - Tissue development" "Cluster 46: Brainstem - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 42: Ciliated cells - Cilium assembly" "HPA076277: AB_2732306" "unprognostic (1.50e-4)" "unprognostic (4.87e-2)" "unprognostic (6.00e-2)" "unprognostic (2.00e-3)" "unprognostic (2.37e-2)" "unprognostic (2.45e-3)" "unprognostic (6.35e-7)" "unprognostic (1.17e-1)" "unprognostic (1.13e-2)" "unprognostic (1.12e-1)" "unprognostic (9.61e-2)" "unprognostic (2.35e-1)" "unprognostic (9.07e-11)" "unprognostic (2.65e-1)" "unprognostic (3.70e-2)" "unprognostic (1.13e-2)" "unprognostic (2.37e-1)" CDHR5 "FLJ20219, MU-PCDH, MUCDHL, MUPCDH" ENSG00000099834 "Cadherin related family member 5" Q9HBB8 11 616577-626078 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 288.9;liver: 126.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 655.8;Intestinal goblet cells: 201.7;Paneth cells: 440.9;Proximal enterocytes: 2282.1" "Cancer enhanced" "Detected in many" "liver cancer: 61.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.7" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009081, HPA009173, CAB025004" Enhanced "Intracellular and membrane" Other NA NA 190000000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "CAB025004: , HPA009081: AB_1079428, HPA009173: AB_1079429" "unprognostic (7.65e-2)" "unprognostic (1.42e-1)" "unprognostic (9.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-3)" "unprognostic (4.89e-2)" "unprognostic (3.85e-2)" "unprognostic (5.75e-2)" "unprognostic (6.36e-2)" "unprognostic (7.95e-2)" "unprognostic (5.07e-2)" "unprognostic (5.01e-2)" "unprognostic (3.90e-1)" "unprognostic (8.85e-2)" "unprognostic (2.29e-1)" "unprognostic (2.14e-2)" CDNF ARMETL1 ENSG00000185267 "Cerebral dopamine neurotrophic factor" Q49AH0 10 14819245-14838575 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 24.9;tongue: 19.5" "Group enriched" "Detected in many" 9 "Early spermatids: 78.4;Late spermatids: 284.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044587 Uncertain "Secreted in other tissues" "Growth factor" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Late spermatids - Unknown function" "HPA044587: AB_10795881" "unprognostic (2.80e-3)" "unprognostic (2.51e-2)" "unprognostic (6.20e-2)" "unprognostic (2.62e-1)" "unprognostic (4.47e-2)" "unprognostic (2.62e-1)" "unprognostic (5.32e-2)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (4.14e-2)" "unprognostic (1.25e-1)" "unprognostic (4.81e-2)" "unprognostic (1.08e-1)" "unprognostic (8.66e-2)" "unprognostic (6.93e-2)" "unprognostic (2.31e-2)" "unprognostic (3.62e-1)" CDSN D6S586E ENSG00000204539 Corneodesmosin 6 31115087-31120446 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "skin 1: 674.3" "Group enriched" "Detected in some" 4 "Cholangiocytes: 3.8;Gastric mucus-secreting cells: 1.8;Glandular and luminal cells: 6.1;Suprabasal keratinocytes: 3.4" "Group enriched" "Detected in some" 8 "head and neck cancer: 2.4;melanoma: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 2.0;head and neck cancer: 1.4" "Skin - Keratinocyte (granular)" "Region enhanced" "Detected in some" "cerebral cortex: 1.5" "Not detected" "Not detected" "HPA044730, HPA054184" Enhanced "Secreted in other tissues" NA NA "Cluster 82: Skin - Keratinization" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA044730: AB_10964923, HPA054184: AB_2682409" "unprognostic (1.46e-1)" "unprognostic (6.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (8.80e-2)" "unprognostic (8.13e-2)" "unprognostic (3.92e-4)" "unprognostic (3.92e-3)" "unprognostic (1.74e-4)" "unprognostic (6.34e-2)" "unprognostic (2.75e-1)" "unprognostic (2.22e-1)" CEACAM1 "BGP, BGP1, CD66a" ENSG00000079385 "CEA cell adhesion molecule 1" P13688 19 42507304-42561234 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 238.1" "Group enriched" "Detected in many" 5 "Distal enterocytes: 797.7;Paneth cells: 241.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 43.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "eosinophil: 44.1;neutrophil: 26.9" "Lineage enriched" "Detected in many" 13 "granulocytes: 44.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Colon - Colon enterocytes, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skin - Eccrine sweat gland cells" "CAB002146, HPA011041" Enhanced "Intracellular and membrane" "No annotated function" NA NA 130000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 5: Enterocytes - Absorption" 2 "CAB002146: AB_563614, HPA011041: AB_1078481" "unprognostic (7.13e-3)" "unprognostic (2.15e-1)" "unprognostic (2.67e-2)" "prognostic favorable (6.32e-7)" "unprognostic (3.04e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-1)" "unprognostic (4.45e-2)" "unprognostic (4.43e-1)" "unprognostic (5.46e-3)" "unprognostic (4.87e-2)" "unprognostic (4.03e-1)" "unprognostic (1.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (7.55e-2)" "unprognostic (5.52e-3)" CEACAM16 DFNA4B ENSG00000213892 "CEA cell adhesion molecule 16, tectorial membrane component" Q2WEN9 19 44699151-44710718 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pancreas: 2.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.3;Rod photoreceptor cells: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045075 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Skeletal myocytes - Muscle contraction" "HPA045075: AB_10959617" "unprognostic (1.27e-1)" "unprognostic (3.73e-1)" "unprognostic (3.12e-1)" "unprognostic (3.32e-2)" "unprognostic (4.72e-1)" "unprognostic (1.42e-2)" "unprognostic (7.76e-2)" "unprognostic (3.59e-2)" "unprognostic (7.81e-3)" "unprognostic (3.88e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.86e-1)" "unprognostic (7.94e-2)" CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 949.3" "Group enriched" "Detected in some" 8 "Distal enterocytes: 1949.2;Intestinal goblet cells: 820.7;Paneth cells: 991.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 196.8;Gallbladder cancer: 484.8" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Thyroid - Parafollicular cells" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 23000000 "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" CEACAM7 "CEA, CGM2" ENSG00000007306 "CEA cell adhesion molecule 7" Q14002 19 41673303-41706976 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 631.6" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 1565.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 66.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.3;colorectal cancer: 3.4;ovarian cancer: 3.2" "Colon - Colon enterocytes" "HPA069621, HPA073910" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" Cytosol "HPA069621: AB_2686162, HPA073910: " "unprognostic (5.24e-2)" "unprognostic (2.72e-1)" "unprognostic (1.64e-2)" "unprognostic (6.03e-2)" "unprognostic (2.07e-2)" "unprognostic (4.30e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.14e-1)" CEACAM8 "CD66b, CGM6" ENSG00000124469 "CEA cell adhesion molecule 8" P31997 19 42580243-42595055 "CD markers, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 214.4" "Cell type enriched" "Detected in single" 4 "Paneth cells: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 1.6;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 6 "granulocytes: 1.6;monocytes: 1.1" "Not detected" "Not detected" "Liver - Erythroid cells, Lung - Neutrophil_1" "CAB033676, CAB080307" Enhanced "Intracellular and membrane" "Cell adhesion" NA NA 9200000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 6: Bone marrow - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 1 "CAB033676: AB_1125678, CAB080307: " "unprognostic (2.01e-1)" "unprognostic (4.52e-2)" "unprognostic (3.31e-1)" "unprognostic (6.30e-2)" "unprognostic (2.68e-1)" "unprognostic (1.62e-1)" "unprognostic (1.71e-2)" "unprognostic (7.77e-2)" "unprognostic (9.62e-2)" CEL "BSSL, MODY8" ENSG00000170835 "Carboxyl ester lipase" P19835 9 133061981-133071861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 545 "pancreas: 107112.3" "Group enriched" "Detected in some" 21 "Breast glandular cells: 371.9;Exocrine glandular cells: 517.2" "Cancer enriched" "Detected in many" 29 "pancreatic cancer: 469.3" "Region enriched" "Detected in all" 4 "choroid plexus: 24.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.1" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008023, HPA052701" Enhanced "Secreted to digestive system" Enzyme NA NA 110000 "Cluster 15: Pancreas - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA008023: AB_1846509, HPA052701: AB_2681921" "prognostic unfavorable (4.14e-4)" "unprognostic (2.30e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-2)" "unprognostic (2.22e-1)" "unprognostic (2.48e-1)" "unprognostic (1.49e-1)" "unprognostic (6.27e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (5.55e-2)" "unprognostic (2.26e-3)" "unprognostic (2.98e-1)" "unprognostic (4.41e-1)" "unprognostic (4.37e-2)" "unprognostic (1.02e-1)" CELA1 ELA1 ENSG00000139610 "Chymotrypsin like elastase 1" Q9UNI1 12 51328442-51346679 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 2.1;pancreas: 6.4" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 6.7;Extravillous trophoblasts: 3.3;Kupffer cells: 8.5;NK-cells: 2.2;Oocytes: 2.2;Pancreatic endocrine cells: 1.7" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 12.6;naive CD4 T-cell: 12.3" "Group enriched" "Detected in many" 8 "granulocytes: 12.6;T-cells: 12.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Secreted - unknown location" Enzyme NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Pancreas - Proteolysis" "Cluster 34: Testis cancer - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" "unprognostic (3.54e-2)" "unprognostic (1.64e-1)" "unprognostic (4.73e-2)" "unprognostic (2.73e-1)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (3.59e-2)" "unprognostic (3.83e-3)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" CELA2A ELA2A ENSG00000142615 "Chymotrypsin like elastase 2A" P08217 1 15456728-15472091 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5427 "pancreas: 157554.2" "Cell type enriched" "Detected in some" 47 "Exocrine glandular cells: 3385.8" "Cancer enriched" "Detected in single" 3818 "pancreatic cancer: 463.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Secreted to digestive system" Enzyme NA NA 2700000 "Cluster 15: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "unprognostic (9.78e-2)" "unprognostic (3.33e-2)" "unprognostic (5.60e-2)" "unprognostic (5.27e-2)" "unprognostic (3.63e-3)" "unprognostic (2.35e-1)" "unprognostic (4.14e-1)" "unprognostic (1.96e-2)" "unprognostic (1.38e-1)" "unprognostic (2.48e-1)" "unprognostic (3.94e-9)" "unprognostic (4.10e-2)" "unprognostic (3.42e-1)" "unprognostic (3.55e-2)" CELA2B "ELA2B, RP11-265F14.2" ENSG00000215704 "Chymotrypsin like elastase 2B" P08218 1 15465909-15491395 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 3898 "pancreas: 19804.1" "Cell type enriched" "Detected in some" 98 "Exocrine glandular cells: 502.5" "Cancer enriched" "Detected in single" 574 "pancreatic cancer: 69.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Secreted to digestive system" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 15: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 3 "unprognostic (4.36e-3)" "unprognostic (5.45e-2)" "unprognostic (6.66e-2)" "unprognostic (5.31e-3)" "unprognostic (4.47e-3)" "unprognostic (1.37e-3)" "unprognostic (4.66e-2)" "unprognostic (6.32e-2)" "unprognostic (2.73e-1)" "unprognostic (2.44e-1)" "unprognostic (2.94e-1)" "unprognostic (3.85e-2)" "unprognostic (1.22e-6)" "unprognostic (2.47e-1)" "unprognostic (6.67e-2)" "unprognostic (1.88e-1)" "unprognostic (7.80e-2)" CELA3A "ELA3, ELA3A" ENSG00000142789 "Chymotrypsin like elastase 3A" P09093 1 22001657-22012542 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5176 "pancreas: 254229.0" "Cell type enriched" "Detected in some" 84 "Exocrine glandular cells: 13898.6" "Cancer enriched" "Detected in some" 2497 "pancreatic cancer: 1481.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" Enzyme NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Pancreatic exocrine cells - Proteolysis" Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (1.27e-1)" "unprognostic (2.71e-1)" "unprognostic (1.79e-1)" "unprognostic (6.32e-2)" "unprognostic (2.67e-1)" CELA3B "CBPP, ELA3B" ENSG00000219073 "Chymotrypsin like elastase 3B" P08861 1 21977022-21998642 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2862 "pancreas: 48049.2" "Cell type enriched" "Detected in some" 52 "Exocrine glandular cells: 5348.5" "Cancer enriched" "Detected in single" 1218 "pancreatic cancer: 408.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells, Stomach - Chief cells, Testis - Late spermatids" "HPA028086, HPA045650" Supported Approved Cytosol "Secreted to digestive system" Enzyme NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Pancreatic exocrine cells - Proteolysis" Cytosol "HPA028086: AB_2672482, HPA045650: AB_2679407" "unprognostic (2.89e-1)" "unprognostic (4.01e-3)" "unprognostic (6.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (6.40e-2)" CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 30.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 29.1;Basal respiratory cells: 28.6;Ciliated cells: 56.5;Club cells: 31.1;Glandular and luminal cells: 35.4;Ionocytes: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA 280000 "Cluster 34: B-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" CEMIP "HYBID, IR2155535, KIAA1199, TMEM2L" ENSG00000103888 "Cell migration inducing hyaluronidase 1" Q8WUJ3 15 80779343-80951776 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 30.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 60.5;Inhibitory neurons: 38.7;Mesothelial cells: 67.7;Microglial cells: 96.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gastric cancer: 60.2" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079449 Supported "Nuclear membrane,Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" Enzyme NA NA 1700000 "Cluster 59: Fallopian tube - Tissue development" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" "Nucleoli fibrillar center" "Nuclear membrane, Endoplasmic reticulum" "HPA079449: " "unprognostic (1.14e-3)" "unprognostic (6.80e-2)" "unprognostic (5.95e-2)" "unprognostic (3.15e-3)" "unprognostic (3.49e-3)" "unprognostic (6.80e-2)" "unprognostic (5.47e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (1.53e-1)" "unprognostic (7.24e-2)" "unprognostic (1.36e-1)" "unprognostic (5.27e-10)" "unprognostic (1.82e-2)" "unprognostic (1.93e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.65e-4)" CEP57 "KIAA0092, Translokin, TSP57" ENSG00000166037 "Centrosomal protein 57" Q86XR8 11 95789965-95832693 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 426.4;Late spermatids: 444.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018315, HPA066403" Approved Supported "Centriolar satellite,Centrosome,Cytosol" "Intracellular and membrane" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 11: Late spermatids - Unknown function" 12 "Centrosome, Cytosol" "Centriolar satellite" "HPA018315: AB_1846537, HPA066403: " "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (1.45e-2)" "unprognostic (2.66e-1)" "prognostic favorable (7.24e-4)" "unprognostic (1.69e-1)" "unprognostic (2.25e-2)" "unprognostic (8.10e-2)" "unprognostic (9.04e-3)" "unprognostic (7.93e-2)" "unprognostic (2.38e-3)" "unprognostic (7.81e-2)" "unprognostic (1.06e-1)" "unprognostic (4.31e-2)" "unprognostic (1.35e-1)" "unprognostic (6.69e-3)" "unprognostic (3.25e-1)" CEP89 "CCDC123, FLJ14640" ENSG00000121289 "Centrosomal protein 89" Q96ST8 19 32875925-32971991 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039382 Supported Cytosol "Intracellular and membrane" Other NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" Cytosol "HPA039382: AB_2676479" "unprognostic (4.23e-2)" "unprognostic (7.50e-3)" "unprognostic (1.97e-1)" "unprognostic (1.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.78e-5)" "unprognostic (1.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.04e-2)" "unprognostic (1.80e-2)" "unprognostic (4.00e-2)" "unprognostic (1.74e-1)" "unprognostic (4.48e-2)" "unprognostic (6.53e-2)" "unprognostic (3.03e-1)" "unprognostic (2.47e-2)" CER1 DAND4 ENSG00000147869 "Cerberus 1, DAN family BMP antagonist" O95813 9 14719724-14722733 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "epididymis: 1.0" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 82 "testis cancer: 17.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 5.6;liver cancer: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019917 Uncertain "Secreted - unknown location" Cytokine NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 53: Fibroblasts - ECM organization" "HPA019917: AB_1846539" "unprognostic (2.98e-2)" "unprognostic (5.36e-2)" "unprognostic (5.99e-2)" CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 356.7;pituitary gland: 101.9" "Cell type enriched" "Detected in many" 8 "Oligodendrocytes: 583.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" 28 "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 2440.5" "Group enriched" "Detected in many" 4 "Cholangiocytes: 635.3;Hepatocytes: 1750.3" "Cancer enriched" "Detected in all" 6 "liver cancer: 711.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 16 "classical monocyte: 109.7;myeloid DC: 114.5" "Group enriched" "Detected in many" 22 "dendritic cells: 114.5;monocytes: 109.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 389.4;liver cancer: 290.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme No NA 40000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "Endoplasmic reticulum" "HPA012023: AB_1846554, HPA046717: AB_2679770" "unprognostic (1.04e-2)" "unprognostic (9.85e-2)" "unprognostic (2.94e-1)" "unprognostic (1.28e-1)" "unprognostic (1.55e-3)" "unprognostic (7.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (5.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.29e-2)" "unprognostic (1.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.92e-1)" "unprognostic (2.87e-1)" "prognostic unfavorable (9.92e-4)" CES2 "CE-2, CES2A1, iCE" ENSG00000172831 "Carboxylesterase 2" O00748 16 66934444-66945096 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 683.3;liver: 335.1" "Group enriched" "Detected in all" 4 "Distal enterocytes: 862.9;Proximal enterocytes: 2605.1" "Cancer enhanced" "Detected in all" "liver cancer: 104.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "HPA018897, HPA074629" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA 6400000 "Cluster 33: Non-specific - ATP binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "Golgi apparatus" "Endoplasmic reticulum, Cytosol" "HPA018897: AB_1846558, HPA074629: " "unprognostic (8.15e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-1)" "unprognostic (2.67e-3)" "unprognostic (2.74e-2)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (1.31e-1)" "unprognostic (6.93e-2)" "unprognostic (7.99e-2)" "unprognostic (1.73e-3)" "unprognostic (2.66e-2)" "prognostic favorable (1.50e-5)" "unprognostic (8.01e-2)" "unprognostic (1.53e-1)" "unprognostic (4.14e-2)" "unprognostic (1.38e-1)" CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961245-66975149 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.1;liver: 51.2;skeletal muscle: 23.9" "Group enriched" "Detected in many" 5 "Distal enterocytes: 106.8;Enteroendocrine cells: 31.6;Hepatocytes: 43.0;Intestinal goblet cells: 27.9;Paneth cells: 74.2;Proximal enterocytes: 63.1;Undifferentiated cells: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 1200000 "Cluster 19: Eosinophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Enterocytes - Absorption" "Nuclear membrane, Endoplasmic reticulum" "HPA041008: AB_2677247, HPA041307: AB_2677400" "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favorable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" CES4A "CES8, FLJ37464" ENSG00000172824 "Carboxylesterase 4A" Q5XG92 16 66988589-67010417 "Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 17.4;skin 1: 13.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 44.7;Ciliated cells: 49.1;Excitatory neurons: 51.8;Oligodendrocytes: 35.0;Spermatocytes: 32.6" "Cancer enhanced" "Detected in many" "renal cancer: 5.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA035701 Approved Approved Cytosol "Secreted - unknown location" Enzyme NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 13: Skin - Cornification" "Cluster 34: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 17: Breast glandular cells - Lactation" Cytosol "HPA035701: AB_10696357" "unprognostic (6.34e-2)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (3.26e-2)" "unprognostic (1.99e-1)" "unprognostic (6.20e-2)" "unprognostic (2.12e-2)" "unprognostic (2.04e-2)" "unprognostic (5.78e-3)" "unprognostic (3.93e-2)" "unprognostic (2.02e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.35e-6)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-3)" CES5A "CAUXIN, CES4C1, CES5, CES7, FLJ31547" ENSG00000159398 "Carboxylesterase 5A" Q6NT32 16 55846154-55956031 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "epididymis: 65.8" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.5;Cholangiocytes: 1.9;Collecting duct cells: 3.9;Excitatory neurons: 1.4;Hepatocytes: 6.6;Oligodendrocyte precursor cells: 1.9;Oligodendrocytes: 3.8;Oocytes: 1.5" "Cancer enriched" "Detected in single" 5 "liver cancer: 0.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted in male reproductive system" Enzyme NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 62: Hepatocytes - Metabolism" "unprognostic (2.07e-1)" "unprognostic (2.55e-1)" "unprognostic (6.34e-2)" "unprognostic (4.82e-2)" "unprognostic (3.78e-1)" "unprognostic (2.33e-1)" "unprognostic (3.12e-2)" "unprognostic (1.72e-7)" "unprognostic (1.55e-2)" "unprognostic (2.27e-1)" CETP BPIFF ENSG00000087237 "Cholesteryl ester transfer protein" P11597 16 56961923-56983845 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adipose tissue: 32.3;liver: 41.7;lymphoid tissue: 58.1;placenta: 35.0" "Group enriched" "Detected in some" 5 "Adipocytes: 41.2;Kupffer cells: 90.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.3;plasmacytoid DC: 3.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 1.4" "Secreted to blood" Transport NA NA 2470000000 360000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "unprognostic (6.52e-2)" "unprognostic (4.17e-3)" "unprognostic (2.48e-1)" "unprognostic (1.00e-1)" "unprognostic (4.01e-3)" "unprognostic (4.03e-3)" "unprognostic (3.56e-2)" "unprognostic (1.41e-1)" "unprognostic (3.05e-3)" "unprognostic (4.92e-3)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" "unprognostic (7.62e-2)" "unprognostic (2.20e-2)" "unprognostic (4.08e-2)" "unprognostic (7.34e-2)" "unprognostic (9.97e-2)" CFAP65 "CCDC108, DKFZp434O0527, MGC35338" ENSG00000181378 "Cilia and flagella associated protein 65" Q6ZU64 2 219002846-219041527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 9.1;fallopian tube: 24.8;retina: 8.9;testis: 9.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 64.5;Early spermatids: 159.9;Enteroendocrine cells: 36.6;Intestinal goblet cells: 31.0;Late spermatids: 147.8" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 10.4" "HPA055156, HPA063406" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" "Plasma membrane, Cytosol" "HPA055156: AB_2682720, HPA063406: " "unprognostic (3.95e-2)" "unprognostic (1.80e-1)" "unprognostic (9.88e-3)" "prognostic favorable (6.08e-5)" "unprognostic (2.18e-2)" "unprognostic (1.04e-2)" "unprognostic (2.20e-1)" "unprognostic (3.76e-3)" "unprognostic (3.71e-1)" "unprognostic (3.03e-1)" "unprognostic (5.58e-3)" "unprognostic (1.43e-1)" "unprognostic (6.62e-3)" "unprognostic (8.04e-2)" "unprognostic (2.81e-2)" "unprognostic (9.60e-2)" "unprognostic (6.60e-2)" CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952086 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 2453.1" "Cell type enhanced" "Detected in many" "Ductal cells: 913.7;Exocrine glandular cells: 569.1;Hepatocytes: 199.3;Mesothelial cells: 453.1;Pancreatic endocrine cells: 368.5" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 34.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" Immunity NA NA 879000000 120000000000 "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" CFC1 "CRYPTIC, HTX2" ENSG00000136698 "Cripto, FRL-1, cryptic family 1" P0CG37 2 130592165-130599575 "Disease related genes, Human disease related genes, Predicted secreted proteins" Gastrulation "Developmental protein" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 32.7;pancreas: 29.8;pituitary gland: 57.7" "Group enriched" "Detected in some" 4 "Bipolar cells: 12.6;Enteroendocrine cells: 8.4;Pancreatic endocrine cells: 20.4" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 4.3" "Region enhanced" "Detected in many" "hypothalamus: 55.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "prostate cancer: 13.7;testis cancer: 3.6" "Adipose visceral - Mesothelial cells, Pancreas - Alpha cells, Pancreas - Beta cells" HPA041773 Uncertain "Secreted - unknown location" "Developmental protein" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA041773: AB_2677664" "unprognostic (6.65e-2)" "unprognostic (2.19e-3)" "unprognostic (1.11e-3)" "unprognostic (2.01e-1)" CFC1B ENSG00000152093 "Cripto, FRL-1, cryptic family 1B" P0CG36 2 130521197-130528604 "Predicted secreted proteins" Gastrulation "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.0;pituitary gland: 2.3" "Group enriched" "Detected in some" 13 "Bipolar cells: 1.3;Gastric mucus-secreting cells: 1.2;Pancreatic endocrine cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041773 Approved "Secreted - unknown location" "Developmental protein" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 25: Bipolar cells - Visual perception" "HPA041773: AB_2677664" CFD "ADN, DF, PFD" ENSG00000197766 "Complement factor D" P00746 19 859453-867884 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1448.6" "Group enriched" "Detected in many" 9 "Fibroblasts: 7755.6;Leydig cells: 5061.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1712.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 1712.8" "Cancer enhanced" "Detected in all" "Leukemia: 84.8" "Liver - Kupffer cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Immunity NA NA 732000000 4400000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 53: Fibroblasts - ECM organization" "unprognostic (3.00e-2)" "unprognostic (6.09e-2)" "unprognostic (2.44e-1)" "unprognostic (1.22e-3)" "unprognostic (6.92e-2)" "unprognostic (5.28e-2)" "unprognostic (8.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.46e-2)" "unprognostic (8.10e-2)" "prognostic favorable (1.77e-4)" "unprognostic (9.53e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (1.23e-1)" "unprognostic (4.55e-2)" "unprognostic (1.92e-2)" "unprognostic (9.75e-2)" CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196651754-196752476 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1645.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 355.9;Hepatocytes: 834.8;Leydig cells: 285.2;Mesothelial cells: 388.2;Ovarian stromal cells: 208.2" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Region enhanced" "Detected in all" "choroid plexus: 43.6" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 17.6" "Lineage enriched" "Detected in single" 56 "T-cells: 17.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 59.2" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" Immunity NA NA 396000000000 100000000000 "Cluster 1: T-cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 53: Fibroblasts - ECM organization" 6 Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196837159 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 224 "liver: 2010.5" "Cell type enhanced" "Detected in some" "Granulosa cells: 65.7;Hepatocytes: 223.4;Kupffer cells: 55.4" "Cancer enriched" "Detected in single" 798 "liver cancer: 182.4" "Region enhanced" "Detected in single" "midbrain: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.3;thyroid cancer: 7.0" "Liver - Hepatocytes" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" "Complement pathway" NA NA 13000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 62: Hepatocytes - Metabolism" 6 Vesicles "HPA038915: AB_2676269, HPA038922: AB_2676271, HPA040726: AB_2677101" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.88e-2)" "prognostic favorable (8.71e-6)" "unprognostic (3.02e-1)" "unprognostic (3.70e-1)" "unprognostic (2.50e-1)" "unprognostic (8.48e-2)" "unprognostic (7.21e-4)" "unprognostic (7.01e-4)" "unprognostic (1.13e-1)" "unprognostic (6.41e-2)" CFHR2 "CFHL2, FHR2, HFL3" ENSG00000080910 "Complement factor H related 2" P36980 1 196943738-196959622 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2840 "liver: 1309.3" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 1227.2" "Cancer enriched" "Detected in single" 175 "liver cancer: 8.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "HPA038915, HPA040726, HPA049813" Supported "Secreted to blood" "Complement pathway" NA NA 4800000000 "Cluster 31: Liver - Plasma proteins" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "HPA038915: AB_2676269, HPA040726: AB_2677101, HPA049813: AB_2680895" "unprognostic (1.25e-2)" CFHR3 "CFHL3, DOWN16, FHR-3, FHR3, HLF4" ENSG00000116785 "Complement factor H related 3" Q02985 1 196774813-196795407 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 982 "liver: 381.0" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 139.6" "Cancer enriched" "Detected in single" 80 "liver cancer: 27.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.6;thyroid cancer: 2.8" "Secreted to blood" "Complement pathway" NA NA 582000000 3100000000 "Cluster 31: Liver - Plasma proteins" "Cluster 9: Non-specific - Receptor signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 62: Hepatocytes - Metabolism" 1 "unprognostic (1.73e-1)" "unprognostic (2.11e-1)" "unprognostic (7.16e-2)" "unprognostic (6.77e-2)" "unprognostic (4.46e-1)" "unprognostic (4.20e-3)" "prognostic favorable (2.86e-5)" "unprognostic (1.78e-1)" "unprognostic (2.05e-2)" "unprognostic (1.98e-1)" "unprognostic (1.19e-2)" "unprognostic (6.11e-3)" "unprognostic (2.06e-10)" "unprognostic (2.67e-4)" "unprognostic (3.00e-1)" "unprognostic (3.29e-2)" "unprognostic (1.32e-1)" CFHR4 "CFHL4, FHR-4, FHR4" ENSG00000134365 "Complement factor H related 4" Q92496 1 196888014-196918795 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 548 "liver: 98.6" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 36.6" "Cancer enriched" "Detected in single" 145 "liver cancer: 13.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Secreted to blood" "Complement pathway" NA NA 170000000 "Cluster 31: Liver - Plasma proteins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 62: Hepatocytes - Metabolism" "unprognostic (5.97e-1)" "prognostic favorable (1.57e-6)" "unprognostic (1.89e-1)" "unprognostic (4.79e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (4.71e-1)" CFHR5 "CFHL5, FHR-5, FHR5" ENSG00000134389 "Complement factor H related 5" Q9BXR6 1 196975010-197009678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1620 "liver: 162.0" "Cell type enriched" "Detected in some" 21 "Hepatocytes: 95.1" "Cancer enriched" "Detected in single" 396 "liver cancer: 57.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "HPA038915, HPA040726" Supported "Secreted to blood" "Complement pathway" NA NA 1900000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 15 "HPA038915: AB_2676269, HPA040726: AB_2677101" "unprognostic (9.12e-3)" CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109731008-109802150 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 952.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 454.5;Muller glia cells: 114.1;Proximal tubular cells: 195.1" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" "Complement pathway" NA NA 12000000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Hepatocytes - Metabolism" 1 "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.0;lymphoid tissue: 57.0" "Cell type enhanced" "Detected in some" "Kupffer cells: 8.4;Langerhans cells: 21.9;Macrophages: 43.6;monocytes: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 8 "classical monocyte: 1169.0;intermediate monocyte: 1275.0;myeloid DC: 995.2;neutrophil: 733.0;non-classical monocyte: 872.6" "Group enriched" "Detected in all" 46 "dendritic cells: 995.2;granulocytes: 733.0;monocytes: 1275.0" "Cancer enriched" "Detected in some" 9 "Leukemia: 12.2" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA072644 Approved Vesicles "Secreted to blood" Immunity NA NA 6200000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 22 Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" CGA "FSHA, GPA1, GPHa, GPHA1, HCG, LHA, TSHA" ENSG00000135346 "Glycoprotein hormones, alpha polypeptide" P01215 6 87085498-87095106 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 4272.4" "Cell type enriched" "Detected in some" 18 "Syncytiotrophoblasts: 113935.8" "Cancer enhanced" "Detected in many" "breast cancer: 10.9;testis cancer: 13.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "cervical cancer: 417.4;testis cancer: 1324.5" "Region enriched" "Detected in many" 6 "hypothalamus: 22.2" "Region enriched" "Detected in all" 18 "hypothalamus: 110.4" "CAB023350, HPA029698" Enhanced "Secreted to blood" Hormone NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 4 "CAB023350: AB_617281, HPA029698: AB_2673153" "unprognostic (1.66e-1)" "unprognostic (2.10e-1)" "unprognostic (3.22e-5)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.69e-2)" "unprognostic (3.17e-1)" "unprognostic (7.04e-3)" "unprognostic (1.51e-1)" "unprognostic (2.85e-1)" "unprognostic (4.32e-2)" "unprognostic (8.32e-2)" "unprognostic (9.15e-3)" CGB1 ENSG00000267631 "Chorionic gonadotropin subunit beta 1" A6NKQ9 19 49035569-49036895 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 11 "pancreas: 2.6;pituitary gland: 4.1" "Cell type enriched" "Detected in some" 103 "Syncytiotrophoblasts: 177.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "HPA038925, HPA038934, CAB080127" Approved "Secreted to blood" Hormone NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 49: HMC-1 - Innate immune response" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "CAB080127: , HPA038925: AB_2676272, HPA038934: AB_2676277" CGB2 ENSG00000104818 "Chorionic gonadotropin subunit beta 2" Q6NT52 19 49031890-49033238 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "testis: 1.5" "Cell type enriched" "Detected in some" 9 "Syncytiotrophoblasts: 22.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA038925, HPA038934" Supported "Secreted in other tissues" Hormone NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (3.05e-2)" CGB3 CGB ENSG00000104827 "Chorionic gonadotropin subunit beta 3" P0DN86 19 49022869-49024333 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 9.5" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 674.4" "Group enriched" "Detected in some" 5 "pancreatic cancer: 2.9;testis cancer: 4.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.0" "CAB000042, CAB010884, HPA038925, HPA038934" Enhanced "Secreted to blood" Hormone NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 2 "CAB000042: , CAB010884: AB_259037, HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (1.39e-1)" "unprognostic (7.88e-2)" "unprognostic (6.92e-2)" "unprognostic (1.04e-2)" CGB5 HCG ENSG00000189052 "Chorionic gonadotropin subunit beta 5" P0DN86 19 49043848-49045311 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pituitary gland: 8.4;placenta: 24.9" "Group enriched" "Detected in some" 11 "Extravillous trophoblasts: 3.2;Syncytiotrophoblasts: 11.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 10.0;testis cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA038925, HPA038934" Supported "Secreted to blood" Hormone NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 2 "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (1.38e-1)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "prognostic unfavorable (1.18e-5)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.47e-4)" CGB7 CG-beta-a ENSG00000196337 "Chorionic gonadotropin subunit beta 7" P0DN87 19 49054274-49058860 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "prostate: 3.5;skin 1: 4.3" "Cell type enriched" "Detected in some" 7 "Syncytiotrophoblasts: 44.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Lung - Respiratory ciliated cells" "HPA038925, HPA038934" Supported "Secreted in other tissues" "No annotated function" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (9.53e-2)" "unprognostic (1.99e-1)" "unprognostic (1.87e-1)" "unprognostic (3.53e-1)" "unprognostic (4.60e-5)" "unprognostic (2.64e-1)" "unprognostic (2.46e-1)" "unprognostic (8.37e-2)" "unprognostic (2.88e-2)" "unprognostic (4.80e-2)" "unprognostic (8.83e-4)" "unprognostic (1.54e-1)" "unprognostic (3.89e-8)" "unprognostic (1.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.05e-1)" "unprognostic (9.28e-2)" CGB8 ENSG00000213030 "Chorionic gonadotropin subunit beta 8" P0DN86 19 49047638-49049111 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "placenta: 18.1" "Cell type enriched" "Detected in some" 7 "Syncytiotrophoblasts: 28.5" "Cancer enriched" "Detected in some" 4 "testis cancer: 5.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 25.3" "HPA038925, HPA038934" Supported "Secreted to blood" Hormone NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 2 "HPA038925: AB_2676272, HPA038934: AB_2676277" "unprognostic (3.35e-2)" "unprognostic (1.72e-1)" "unprognostic (7.44e-3)" "unprognostic (4.70e-1)" "unprognostic (1.67e-2)" CGREF1 CGR11 ENSG00000138028 "Cell growth regulator with EF-hand domain 1" Q99674 2 27098889-27119128 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.3" "Cell type enriched" "Detected in many" 14 "Oocytes: 227.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008241, HPA071103" Uncertain Approved "Golgi apparatus" "Secreted in brain" "Cell adhesion" NA NA 700000 "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 44: Oocytes - Unknown function" 1 "Golgi apparatus" "HPA008241: AB_1846605, HPA071103: " "unprognostic (1.39e-2)" "unprognostic (1.26e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (8.45e-2)" "unprognostic (3.99e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (5.22e-2)" "unprognostic (7.34e-2)" "unprognostic (1.92e-1)" "unprognostic (2.57e-1)" "unprognostic (2.27e-1)" "unprognostic (2.52e-3)" "unprognostic (1.05e-1)" "unprognostic (2.30e-2)" "unprognostic (7.24e-4)" "unprognostic (1.20e-2)" CHAD SLRR4A ENSG00000136457 Chondroadherin O15335 17 50464496-50468906 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.9;liver: 35.4;pancreas: 31.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 3.7;Distal enterocytes: 4.0;Gastric mucus-secreting cells: 2.9;Intestinal goblet cells: 10.7;Oligodendrocyte precursor cells: 5.2" "Group enriched" "Detected in many" 5 "breast cancer: 23.7;liver cancer: 10.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "memory B-cell: 21.6;naive B-cell: 8.1" "Lineage enriched" "Detected in single" 76 "B-cells: 21.6" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA018241 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 22000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 68: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA018241: AB_1846612" "prognostic favorable (7.68e-4)" "unprognostic (4.34e-2)" "unprognostic (1.24e-1)" "unprognostic (9.67e-3)" "unprognostic (1.92e-1)" "unprognostic (3.06e-3)" "prognostic favorable (1.59e-4)" "unprognostic (1.51e-2)" "unprognostic (4.75e-2)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-2)" "unprognostic (1.51e-3)" "unprognostic (1.41e-3)" CHADL SLRR4B ENSG00000100399 "Chondroadherin like" Q6NUI6 22 41229510-41240931 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 104.1" "Cell type enhanced" "Detected in many" "Melanocytes: 42.9;Muller glia cells: 40.4;Oligodendrocytes: 77.3;Schwann cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005696, HPA024654" Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "HPA005696: AB_1079724, HPA024654: AB_1846615" "unprognostic (6.14e-2)" "unprognostic (4.42e-3)" "unprognostic (1.49e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (9.51e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.56e-4)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (2.83e-3)" "unprognostic (1.51e-2)" "unprognostic (4.67e-8)" "unprognostic (8.36e-3)" "unprognostic (4.10e-1)" "unprognostic (3.40e-1)" "unprognostic (4.09e-2)" CHGA "PHE5, PHES" ENSG00000100604 "Chromogranin A" P10645 14 92923150-92935285 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 6356.0" "Cell type enriched" "Detected in many" 10 "Enteroendocrine cells: 13879.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 114.8" "Group enriched" "Detected in all" 6 "cerebral cortex: 857.5;white matter: 400.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 570.3" "Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Sertoli cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000023, HPA017369, CAB040544, CAB055506, CAB058688" Enhanced Supported Vesicles "Intracellular and membrane" Defense NA NA 295000000 100000000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" Vesicles "CAB000023: , CAB040544: , CAB055506: AB_2081135, CAB058688: AB_2665574, HPA017369: AB_1846698" "prognostic favorable (7.85e-5)" "unprognostic (4.89e-2)" "unprognostic (5.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.43e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (4.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (1.85e-1)" "unprognostic (8.81e-13)" "unprognostic (1.07e-2)" "unprognostic (1.77e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (3.99e-4)" CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 3361.4;brain: 677.1;pituitary gland: 1387.3" "Group enriched" "Detected in many" 6 "Enteroendocrine cells: 1190.5;Pancreatic endocrine cells: 640.1" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gastric cancer: 77.4;lung cancer: 63.1;Neuroblastoma: 230.8;thyroid cancer: 195.7" "Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Pancreas - Alpha cells, Testis - Spermatocytes, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" "No annotated function" NA NA 6500000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favorable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 358.0;liver: 436.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 124.1;Basal respiratory cells: 92.1;Ductal cells: 96.0;Hofbauer cells: 281.4;Mesothelial cells: 205.9" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 494 "neutrophil: 472.1" "Lineage enriched" "Detected in single" 494 "granulocytes: 472.1" "Group enriched" "Detected in many" 4 "Bile duct cancer: 271.9;Brain cancer: 202.6" "Kidney - Podocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 6 "olfactory bulb: 28.3" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" Defense NA NA 25100000 180000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Alveolar cells - Lung function" 2 "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" CHI3L2 "YKL-39, YKL39" ENSG00000064886 "Chitinase 3 like 2" Q15782 1 111200771-111243440 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 195.4;salivary gland: 137.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 108.5;B-cells: 63.5;Leydig cells: 77.3;Melanocytes: 39.5;Mucus glandular cells: 57.2;Serous glandular cells: 178.7" "Cancer enriched" "Detected in many" 8 "glioma: 104.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 91.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 153.8;lymphoma: 103.9" "Stomach - Macrophages" "Low region specificity" "Detected in all" HPA005443 Approved "Secreted to blood" Enzyme NA NA 420000 "Cluster 24: Non-specific - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA005443: AB_1078510" "unprognostic (1.02e-2)" "unprognostic (4.34e-2)" "unprognostic (1.37e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (9.10e-5)" "prognostic favorable (2.19e-4)" "unprognostic (7.12e-2)" "unprognostic (1.39e-1)" "unprognostic (1.49e-3)" "unprognostic (1.26e-2)" "unprognostic (1.32e-2)" "unprognostic (2.44e-2)" "prognostic unfavorable (8.59e-7)" "unprognostic (7.15e-3)" "unprognostic (7.68e-2)" "unprognostic (1.39e-3)" "unprognostic (1.20e-1)" CHIA "AMCase, CHIT2, TSA1902" ENSG00000134216 "Chitinase acidic" Q9BZP6 1 111290851-111320566 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Carbohydrate metabolism, Chitin degradation, Immunity, Inflammatory response, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "stomach 1: 318.6" "Group enriched" "Detected in some" 6 "Alveolar cells type 2: 11.6;Glandular and luminal cells: 3.9;Late spermatids: 6.4" "Group enriched" "Detected in some" 4 "lung cancer: 1.8;stomach cancer: 2.0;thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Alveolar cells type 2, Stomach - Chief cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA059193 Approved "Intracellular and membrane" Immunity NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 3 "HPA059193: AB_2683942" "unprognostic (8.00e-2)" "unprognostic (7.08e-2)" "unprognostic (2.02e-2)" "unprognostic (4.99e-2)" "unprognostic (7.93e-2)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" CHID1 "FLJ42707, MGC3234, SI-CLP" ENSG00000177830 "Chitinase domain containing 1" Q9BWS9 11 867859-915058 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 398.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039374 Uncertain Uncertain "Nucleoplasm,Intermediate filaments" "Intracellular and membrane" Immunity No No 1500000 "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "Nucleoplasm, Intermediate filaments" "HPA039374: AB_10673609" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (8.96e-2)" "prognostic favorable (6.76e-4)" "unprognostic (4.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.97e-2)" "unprognostic (3.62e-2)" "unprognostic (7.88e-2)" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (5.21e-2)" "unprognostic (1.74e-3)" "unprognostic (1.15e-1)" "unprognostic (7.53e-2)" "unprognostic (3.29e-2)" "unprognostic (2.89e-2)" CHIT1 "CHI3, CHIT" ENSG00000133063 "Chitinase 1" Q13231 1 203212827-203273641 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.2;lung: 35.3;lymphoid tissue: 21.2" "Cell type enhanced" "Detected in some" "Club cells: 44.1;granulocytes: 15.1;Hofbauer cells: 35.1;Macrophages: 71.9" "Cancer enhanced" "Detected in many" "testis cancer: 31.9" "Region enhanced" "Detected in some" "white matter: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010575, HPA074844" Enhanced "Secreted to blood" Enzyme NA NA 26400000 57000000 "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" "HPA010575: AB_1078512, HPA074844: " "unprognostic (5.80e-3)" "prognostic favorable (2.02e-4)" "unprognostic (2.58e-2)" "unprognostic (2.19e-1)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.55e-2)" "unprognostic (6.36e-3)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.56e-3)" "unprognostic (3.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" CHL1 "CALL, FLJ44930, L1CAM2, MGC132578" ENSG00000134121 "Cell adhesion molecule L1 like" O00533 3 196763-409417 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.0;ovary: 32.7" "Cell type enhanced" "Detected in many" "Astrocytes: 212.1;Excitatory neurons: 409.9;Inhibitory neurons: 307.2;Oligodendrocyte precursor cells: 861.7;Schwann cells: 403.3" "Cancer enhanced" "Detected in many" "glioma: 15.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 33 "memory B-cell: 2.8;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 38 "B-cells: 3.8" "Group enriched" "Detected in many" 7 "Rhabdoid: 38.6;skin cancer: 30.5" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003345, CAB026120" Enhanced "Secreted in brain" "Developmental protein" NA NA 5800000000 "Cluster 34: B-cells - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "CAB026120: , HPA003345: AB_1078516" "unprognostic (5.54e-2)" "unprognostic (2.08e-1)" "unprognostic (7.45e-2)" "unprognostic (7.14e-3)" "unprognostic (1.16e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-2)" "unprognostic (2.22e-1)" "unprognostic (5.14e-1)" "unprognostic (1.06e-1)" "unprognostic (7.81e-2)" "unprognostic (3.51e-1)" "prognostic favorable (1.21e-6)" "unprognostic (1.11e-1)" "unprognostic (6.07e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" CHPF "CHSY2, CSS2" ENSG00000123989 "Chondroitin polymerizing factor" Q8IZ52 2 219538954-219543809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.0;Extravillous trophoblasts: 197.2;Syncytiotrophoblasts: 314.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035123 Approved Supported Vesicles,Centrosome,Cytosol "Intracellular and membrane" Enzyme NA NA 570000 "Cluster 22: Eosinophils - Transcription" "Cluster 46: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 77: Plasma cells - Protein processing" Cytosol "Vesicles, Centrosome" "HPA035123: AB_10602799" "unprognostic (1.13e-3)" "prognostic unfavorable (1.57e-4)" "unprognostic (3.65e-3)" "unprognostic (2.55e-3)" "unprognostic (1.86e-3)" "prognostic unfavorable (1.68e-4)" "unprognostic (1.37e-1)" "unprognostic (6.59e-3)" "unprognostic (7.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (6.79e-2)" "unprognostic (1.64e-1)" "unprognostic (6.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (2.96e-4)" CHPF2 "ChSy-3, CSGlcA-T, KIAA1402" ENSG00000033100 "Chondroitin polymerizing factor 2" Q9P2E5 7 151232483-151240979 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020992 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" "Nucleoplasm, Cytosol" "HPA020992: AB_1847267" "unprognostic (8.31e-2)" "unprognostic (2.14e-3)" "unprognostic (1.02e-3)" "unprognostic (1.14e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "prognostic unfavorable (9.47e-4)" "unprognostic (4.07e-1)" "unprognostic (1.71e-1)" "unprognostic (4.54e-2)" "prognostic favorable (2.51e-4)" "unprognostic (1.04e-1)" "unprognostic (2.68e-3)" "unprognostic (2.24e-1)" "unprognostic (1.49e-1)" "unprognostic (3.22e-2)" "unprognostic (8.59e-3)" CHRD ENSG00000090539 Chordin Q9H2X0 3 184380054-184390736 "Plasma proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.9;liver: 126.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 28.3;Excitatory neurons: 27.3;Fibroblasts: 16.1;Hepatocytes: 25.1;Horizontal cells: 15.1;Inhibitory neurons: 36.1;Smooth muscle cells: 18.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 7.6" HPA035827 Approved "Secreted in other tissues" "Developmental protein" NA NA 350000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Smooth muscle cells - Signal transduction" 40 "HPA035827: AB_10669657" "unprognostic (2.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.63e-2)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.12e-1)" "unprognostic (3.12e-2)" "unprognostic (6.55e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (5.53e-3)" "unprognostic (1.85e-1)" "unprognostic (9.84e-2)" "unprognostic (7.99e-3)" CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 216.7" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Fibroblasts: 82.7;Leydig cells: 38.5;Lymphatic endothelial cells: 152.5;Mesothelial cells: 48.5;Muller glia cells: 64.5" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 59.3" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" "Developmental protein" NA NA 610000 "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" CHRDL2 BNF1 ENSG00000054938 "Chordin like 2" Q6WN34 11 74696429-74731426 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 139.9;gallbladder: 102.5;lymphoid tissue: 112.6;smooth muscle: 117.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 181.9;Early spermatids: 43.2;Hepatocytes: 114.5" "Cancer enhanced" "Detected in many" "stomach cancer: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 5.1;lung cancer: 3.1" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021771, HPA076522" Uncertain Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 9700000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 17: Breast glandular cells - Lactation" Vesicles "HPA021771: AB_1846689, HPA076522: " "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (7.24e-2)" "unprognostic (3.41e-3)" "unprognostic (9.45e-2)" "unprognostic (2.09e-1)" "unprognostic (4.08e-2)" "unprognostic (4.33e-2)" "unprognostic (6.64e-2)" "unprognostic (2.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.23e-1)" "unprognostic (7.58e-6)" "unprognostic (8.39e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (6.08e-4)" CHST1 "C6ST, KSGal6ST" ENSG00000175264 "Carbohydrate sulfotransferase 1" O43916 11 45647689-45665622 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.5" "Cell type enhanced" "Detected in many" "Astrocytes: 36.5;Early spermatids: 92.5;Excitatory neurons: 23.1;Serous glandular cells: 31.2;Spermatocytes: 75.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA 10000 "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 2 "unprognostic (1.77e-2)" "unprognostic (1.67e-1)" "unprognostic (6.37e-3)" "unprognostic (1.32e-1)" "unprognostic (2.18e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.95e-4)" "unprognostic (6.22e-2)" "unprognostic (1.64e-1)" "unprognostic (1.39e-1)" "unprognostic (1.09e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (4.64e-7)" "unprognostic (5.37e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" CHST10 HNK-1ST ENSG00000115526 "Carbohydrate sulfotransferase 10" O43529 2 100391860-100417668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 20.4;Horizontal cells: 14.5;Muller glia cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012884, HPA051545" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA 680000 "Cluster 24: Non-specific - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" Cytosol "HPA012884: AB_1846710, HPA051545: AB_2681529" "unprognostic (5.40e-3)" "unprognostic (3.62e-2)" "unprognostic (3.44e-2)" "unprognostic (2.03e-1)" "unprognostic (3.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.89e-2)" "unprognostic (1.44e-1)" "unprognostic (1.78e-1)" "unprognostic (4.54e-2)" "prognostic favorable (4.05e-4)" "unprognostic (8.02e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-2)" "unprognostic (3.73e-2)" "unprognostic (3.06e-2)" "unprognostic (3.27e-1)" CHST11 "C4ST, C4St-1, C4ST1, HSA269537" ENSG00000171310 "Carbohydrate sulfotransferase 11" Q9NPF2 12 104455295-104762014 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.5;choroid plexus: 33.8" "Group enriched" "Detected in many" 4 "Microglial cells: 268.4;Oligodendrocyte precursor cells: 950.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.8;eosinophil: 11.3;neutrophil: 15.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 15.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052828 Approved Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 55000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Golgi apparatus" "HPA052828: AB_2681966" "unprognostic (6.35e-2)" "unprognostic (2.68e-3)" "unprognostic (2.28e-2)" "unprognostic (7.53e-2)" "unprognostic (3.45e-2)" "unprognostic (2.64e-2)" "unprognostic (1.64e-3)" "unprognostic (9.21e-3)" "unprognostic (3.12e-1)" "unprognostic (9.02e-2)" "unprognostic (1.22e-2)" "unprognostic (5.44e-2)" "prognostic unfavorable (7.59e-11)" "unprognostic (1.64e-2)" "unprognostic (5.60e-2)" "unprognostic (5.40e-3)" "prognostic unfavorable (8.42e-4)" CHST13 C4ST3 ENSG00000180767 "Carbohydrate sulfotransferase 13" Q8NET6 3 126524155-126543291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 58.1;testis: 17.8" "Cell type enhanced" "Detected in some" "Early spermatids: 151.6;Hepatocytes: 33.1;Spermatocytes: 102.2" "Group enriched" "Detected in many" 4 "liver cancer: 25.0;renal cancer: 6.3" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 5 "eosinophil: 155.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 155.5" "Cancer enhanced" "Detected in some" "liver cancer: 14.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067960 Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 83: Liver - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "Golgi apparatus" "HPA067960: " "unprognostic (5.68e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-2)" "unprognostic (6.42e-4)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (8.45e-3)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.13e-1)" "unprognostic (1.98e-1)" "unprognostic (5.75e-2)" "unprognostic (5.16e-2)" "unprognostic (6.68e-2)" "unprognostic (2.26e-1)" "unprognostic (1.59e-2)" CHST4 "HEC-GLCNAC-6-ST, LSST" ENSG00000140835 "Carbohydrate sulfotransferase 4" Q8NCG5 16 71525233-71538748 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "gallbladder: 67.1" "Cell type enriched" "Detected in some" 27 "Cholangiocytes: 173.6" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 10.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 13.1;pancreatic cancer: 6.4" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021955 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "HPA021955: AB_1846723" "unprognostic (2.22e-3)" "unprognostic (1.41e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-2)" "unprognostic (4.76e-3)" "unprognostic (6.86e-2)" "prognostic unfavorable (9.24e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-6)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" CHST5 "FLJ22167, I-GLCNAC-6-ST" ENSG00000135702 "Carbohydrate sulfotransferase 5" Q9GZS9 16 75528530-75536108 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 84.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4.8;Enteroendocrine cells: 6.2;Excitatory neurons: 2.1;Intestinal goblet cells: 6.1;Paneth cells: 3.2;Proximal enterocytes: 9.8" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.4;stomach cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.4" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells" "HPA043804, HPA068029" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA043804: AB_10960563, HPA068029: " "unprognostic (6.82e-3)" "unprognostic (2.02e-1)" "unprognostic (1.99e-3)" "unprognostic (1.03e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-2)" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (2.09e-2)" "unprognostic (9.03e-3)" "unprognostic (4.27e-2)" "unprognostic (2.05e-3)" "unprognostic (3.56e-1)" "unprognostic (2.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.42e-2)" CHST6 MCDC1 ENSG00000183196 "Carbohydrate sulfotransferase 6" Q9GZX3 16 75472052-75495445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.2;brain: 9.1;cervix: 9.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 14.2;Ciliated cells: 65.1;Club cells: 12.5;Ionocytes: 39.0;Oligodendrocytes: 15.8;Serous glandular cells: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 6.8" "Lung - Respiratory ciliated cells" HPA068029 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 42: Ciliated cells - Cilium assembly" "HPA068029: " "unprognostic (2.28e-2)" "unprognostic (2.25e-2)" "unprognostic (1.07e-1)" "unprognostic (3.93e-3)" "unprognostic (3.30e-2)" "unprognostic (4.02e-2)" "unprognostic (7.15e-2)" "unprognostic (1.73e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (3.16e-2)" "unprognostic (1.07e-1)" "unprognostic (1.10e-7)" "unprognostic (1.23e-1)" "unprognostic (1.14e-1)" "unprognostic (5.78e-2)" "unprognostic (2.80e-4)" CHST7 "C6ST-2, C6ST2" ENSG00000147119 "Carbohydrate sulfotransferase 7" Q9NS84 X 46573765-46598496 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 34.1" "Cell type enhanced" "Detected in many" "Langerhans cells: 55.1;monocytes: 97.1;Ovarian stromal cells: 46.2;Peritubular cells: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.6" "Group enriched" "Detected in many" 10 "granulocytes: 10.9;monocytes: 10.3;T-cells: 18.6" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003919, HPA030503" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 9800 "Cluster 33: Non-specific - ATP binding" "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" "Nucleoplasm, Vesicles" "HPA003919: AB_10601258, HPA030503: " "unprognostic (3.16e-1)" "prognostic favorable (7.20e-4)" "unprognostic (1.11e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" "unprognostic (7.85e-2)" "unprognostic (9.82e-3)" "unprognostic (3.52e-2)" "unprognostic (2.61e-1)" "unprognostic (2.81e-1)" "unprognostic (2.39e-3)" "unprognostic (6.71e-2)" "unprognostic (1.19e-1)" "unprognostic (8.85e-3)" "unprognostic (8.28e-2)" "unprognostic (1.50e-1)" "unprognostic (4.39e-2)" CHST8 GALNAC4ST-1 ENSG00000124302 "Carbohydrate sulfotransferase 8" Q9H2A9 19 33621953-33773509 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "brain: 17.7;pituitary gland: 62.2" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Excitatory neurons: 11.4;Granulosa cells: 10.8;Horizontal cells: 13.2;Late spermatids: 54.1;Oligodendrocyte precursor cells: 11.3;Pancreatic endocrine cells: 13.6" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;glioma: 4.9;testis cancer: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 12.0" "Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016004 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Late spermatids - Unknown function" 2 "HPA016004: AB_1846731" "unprognostic (1.00e-1)" "unprognostic (6.58e-2)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (9.44e-2)" "unprognostic (2.96e-2)" "unprognostic (1.15e-2)" "unprognostic (5.75e-2)" "unprognostic (8.41e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.54e-1)" "unprognostic (6.98e-8)" "unprognostic (9.37e-3)" "unprognostic (2.61e-1)" "unprognostic (3.28e-1)" "unprognostic (3.87e-2)" CHST9 "GALNAC-4-ST2, GALNAC4ST-2" ENSG00000154080 "Carbohydrate sulfotransferase 9" Q7L1S5 18 26906481-27185308 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 13.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 60.2;Ciliated cells: 140.9;Club cells: 130.0;Ionocytes: 89.1;Muller glia cells: 57.7;Oligodendrocyte precursor cells: 157.1;Salivary duct cells: 111.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 5.9;liver cancer: 10.6" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA011393 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA011393: AB_1846733" "unprognostic (9.24e-3)" "unprognostic (1.13e-2)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (4.53e-3)" "unprognostic (9.98e-3)" "unprognostic (9.21e-3)" "unprognostic (7.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.04e-2)" "unprognostic (3.54e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (3.93e-3)" CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175727-101252048 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "monocytes: 417.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" CHSY3 "CHSY-2, CSS3" ENSG00000198108 "Chondroitin sulfate synthase 3" Q70JA7 5 129904465-130186634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 5.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 491.2;Inhibitory neurons: 334.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044612 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" "HPA044612: AB_10795883" "unprognostic (3.43e-2)" "unprognostic (6.28e-3)" "unprognostic (1.76e-2)" "unprognostic (5.83e-2)" "unprognostic (5.88e-2)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (9.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.08e-6)" "unprognostic (5.22e-3)" "unprognostic (9.93e-2)" "unprognostic (4.61e-3)" "unprognostic (1.74e-2)" CIAO2A "CIA2A, FAM96A, FLJ22875" ENSG00000166797 "Cytosolic iron-sulfur assembly component 2A" Q9H5X1 15 64072565-64093857 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 254.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 289.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040459, HPA063729" Approved Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" Other No No "Cluster 23: B-cells - Immunoglobulins" "Cluster 35: Non-specific - Mitochondria" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 43: Hepatocytes - Metabolism" 21 "Nucleoplasm, Cytosol" "HPA040459: AB_10796456, HPA063729: AB_2685105" "unprognostic (1.15e-1)" "unprognostic (8.49e-2)" "unprognostic (6.59e-2)" "unprognostic (3.58e-1)" "unprognostic (1.30e-1)" "unprognostic (8.07e-2)" "unprognostic (4.06e-3)" "unprognostic (5.02e-2)" "unprognostic (7.16e-2)" "unprognostic (5.87e-2)" "unprognostic (1.04e-1)" "unprognostic (6.48e-3)" "unprognostic (8.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.58e-1)" "unprognostic (2.11e-2)" "unprognostic (1.50e-2)" CILP HsT18872 ENSG00000138615 "Cartilage intermediate layer protein" O75339 15 65194760-65211473 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 40.5;Fibroblasts: 160.9;Leydig cells: 222.4;Peritubular cells: 55.4;Skeletal myocytes: 73.2" "Cancer enhanced" "Detected in many" "breast cancer: 30.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "ovarian cancer: 2.8;Uterine cancer: 3.7" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003195 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 13000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" "HPA003195: AB_1078524" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (4.22e-2)" "unprognostic (7.18e-2)" "unprognostic (2.94e-1)" "unprognostic (2.28e-1)" "unprognostic (2.60e-1)" "unprognostic (1.14e-1)" "unprognostic (1.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.31e-13)" "unprognostic (5.10e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (2.24e-5)" "unprognostic (4.68e-3)" CILP2 MGC45771 ENSG00000160161 "Cartilage intermediate layer protein 2" Q8IUL8 19 19538248-19546659 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.4;testis: 5.4" "Group enriched" "Detected in some" 7 "Early spermatids: 26.2;Late spermatids: 21.5;Spermatocytes: 22.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "medulla oblongata: 3.5;spinal cord: 9.6" HPA041847 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 22000000 "Cluster 74: Spermatids - Flagellum assembly" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 4: Non-specific - Transcription" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA041847: AB_10795599" "unprognostic (6.51e-2)" "unprognostic (2.54e-2)" "unprognostic (5.42e-4)" "prognostic unfavorable (3.22e-6)" "unprognostic (4.81e-2)" "unprognostic (1.73e-1)" "unprognostic (4.31e-2)" "unprognostic (4.13e-3)" "unprognostic (4.48e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (5.09e-2)" "unprognostic (1.41e-2)" "unprognostic (0.00e+0)" "unprognostic (1.59e-2)" "unprognostic (3.19e-2)" "unprognostic (3.12e-3)" "unprognostic (1.36e-2)" CKLF "C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1" ENSG00000217555 "Chemokine like factor" Q9UBR5 16 66552563-66566251 "Predicted membrane proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 384.4;Hofbauer cells: 290.4;Langerhans cells: 258.0;Spermatocytes: 267.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1394.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA062779 Approved Vesicles "Secreted to blood" Cytokine NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 30: Granulocytes - Unknown function" 1 Vesicles "HPA062779: AB_2684867" "unprognostic (1.64e-2)" "unprognostic (2.17e-2)" "unprognostic (1.88e-1)" "unprognostic (4.97e-2)" "unprognostic (3.06e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.79e-2)" "unprognostic (8.05e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.06e-9)" "unprognostic (2.36e-1)" "unprognostic (2.65e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.07e-1)" CKMT1A CKMT1 ENSG00000223572 "Creatine kinase, mitochondrial 1A" P12532 15 43692886-43699222 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.7;esophagus: 81.5;intestine: 72.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 66.6;Distal enterocytes: 151.6;Enteroendocrine cells: 75.9;Paneth cells: 63.3;Proximal enterocytes: 79.8;Syncytiotrophoblasts: 77.2;Undifferentiated cells: 81.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA043491 Uncertain "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 10 "HPA043491: AB_2678510" "unprognostic (2.04e-2)" "unprognostic (2.53e-2)" "unprognostic (1.17e-1)" "unprognostic (4.02e-3)" "unprognostic (3.80e-1)" "unprognostic (7.44e-2)" "unprognostic (2.21e-1)" "unprognostic (3.10e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.51e-2)" "unprognostic (3.78e-9)" "unprognostic (3.52e-2)" "unprognostic (1.03e-1)" "unprognostic (7.37e-2)" "unprognostic (1.73e-3)" CKMT1B "CKMT, CKMT1, UMTCK" ENSG00000237289 "Creatine kinase, mitochondrial 1B" P12532 15 43593054-43604901 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.7;esophagus: 72.2;intestine: 78.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 109.4;Distal enterocytes: 198.6;Enteroendocrine cells: 79.9;Intestinal goblet cells: 75.9;Paneth cells: 69.9;Proximal enterocytes: 122.2;Syncytiotrophoblasts: 107.6;Undifferentiated cells: 93.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA043491 Uncertain "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 10 "HPA043491: AB_2678510" "unprognostic (3.47e-2)" "unprognostic (9.73e-3)" "unprognostic (3.10e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (1.29e-1)" "unprognostic (1.96e-1)" "unprognostic (5.19e-2)" "unprognostic (2.84e-1)" "unprognostic (3.64e-1)" "unprognostic (5.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-2)" "unprognostic (2.26e-8)" "unprognostic (1.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.43e-2)" "unprognostic (4.36e-2)" CLCA1 "CaCC, CLCRG1" ENSG00000016490 "Chloride channel accessory 1" A8K7I4 1 86468368-86500259 "Predicted secreted proteins, Transporters" "Calcium transport, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 1360.5" "Cell type enriched" "Detected in some" 40 "Intestinal goblet cells: 5696.5" "Group enriched" "Detected in some" 9 "colorectal cancer: 86.8;pancreatic cancer: 27.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "ovarian cancer: 27.7" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052787, HPA059301" Enhanced "Secreted to digestive system" Transport NA NA 77000 "Cluster 45: Intestine - Digestion" "Cluster 66: Non-specific - Mitochondria" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA052787: AB_2681947, HPA059301: AB_2683971" "prognostic favorable (2.98e-4)" "unprognostic (3.42e-1)" "unprognostic (8.61e-2)" "unprognostic (1.06e-1)" CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 113.7;skin 1: 86.4;vagina: 51.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 123.9;Basal respiratory cells: 50.8;Basal squamous epithelial cells: 62.7;Club cells: 62.1;Squamous epithelial cells: 183.6;Suprabasal keratinocytes: 212.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 146.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 24.6;Esophageal cancer: 13.5;Gallbladder cancer: 13.2;head and neck cancer: 29.1" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Mitotic cells (Skin), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" Transport NA NA 96000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: AB_2679977" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-3)" "unprognostic (6.99e-2)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (9.99e-3)" "unprognostic (1.97e-8)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" CLCA4 CaCC2 ENSG00000016602 "Chloride channel accessory 4" Q14CN2 1 86547078-86580754 "Predicted membrane proteins, Transporters" Transport "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 363.5;intestine: 249.8" "Cell type enhanced" "Detected in some" "Club cells: 70.9;Distal enterocytes: 299.7;Paneth cells: 118.9;Squamous epithelial cells: 192.5;Suprabasal keratinocytes: 97.4" "Cancer enhanced" "Detected in many" "cervical cancer: 21.4;urothelial cancer: 15.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bladder cancer: 10.1" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA017045, HPA064770" Uncertain Approved "Nucleoplasm,Plasma membrane,Aggresome" "Intracellular and membrane" Transport NA NA 150000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" "Nucleoplasm, Aggresome" "HPA017045: AB_2291679, HPA064770: " "unprognostic (1.38e-4)" "unprognostic (1.52e-1)" "prognostic favorable (7.47e-4)" "unprognostic (2.73e-2)" "unprognostic (7.03e-2)" "prognostic favorable (8.63e-4)" "unprognostic (7.59e-2)" "unprognostic (3.35e-1)" "unprognostic (1.26e-1)" "unprognostic (6.01e-2)" "unprognostic (1.20e-1)" "unprognostic (2.57e-2)" "unprognostic (2.29e-1)" "unprognostic (5.69e-2)" "unprognostic (3.43e-2)" CLCF1 "BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6" ENSG00000175505 "Cardiotrophin like cytokine factor 1" Q9UBD9 11 67364168-67374177 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 101.7;monocytes: 31.9;Secretory cells: 84.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 3.9" HPA042444 Uncertain Approved "Nuclear bodies,Vesicles" "Secreted to blood" Cytokine NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "Nuclear bodies, Vesicles" "HPA042444: AB_10794527" "unprognostic (2.68e-1)" "unprognostic (7.87e-3)" "unprognostic (6.21e-3)" "unprognostic (2.62e-2)" "prognostic unfavorable (9.91e-4)" "unprognostic (1.61e-2)" "unprognostic (1.09e-3)" "unprognostic (1.47e-2)" "unprognostic (5.08e-2)" "unprognostic (2.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.54e-1)" "unprognostic (1.67e-2)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.17e-2)" "unprognostic (2.37e-1)" CLEC11A "CLECSF3, LSLCL, P47, SCGF" ENSG00000105472 "C-type lectin domain containing 11A" Q9Y240 19 50723364-50725708 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 114.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 129.1;Fibroblasts: 97.6;Melanocytes: 113.4;Ovarian stromal cells: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 306.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042690 Approved Approved Centrosome "Secreted in other tissues" "Growth factor" NA NA 1300000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 35: RS4;11 - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 6 Centrosome "HPA042690: AB_10795511" "unprognostic (9.33e-2)" "unprognostic (6.66e-2)" "unprognostic (2.40e-2)" "prognostic favorable (6.91e-4)" "unprognostic (2.33e-1)" "unprognostic (8.22e-2)" "unprognostic (5.52e-2)" "unprognostic (1.29e-2)" "unprognostic (5.26e-2)" "unprognostic (4.99e-2)" "unprognostic (2.79e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (1.02e-5)" "unprognostic (6.09e-2)" "unprognostic (8.66e-3)" "unprognostic (4.00e-2)" "unprognostic (1.57e-2)" CLEC18A MRCL ENSG00000157322 "C-type lectin domain family 18 member A" A5D8T8 16 69950705-69964452 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 15.9;kidney: 23.2" "Cell type enriched" "Detected in some" 8 "Proximal tubular cells: 68.3" "Cancer enriched" "Detected in single" 7 "renal cancer: 1.5" "Region enhanced" "Detected in some" "choroid plexus: 6.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lung cancer: 3.8" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" HPA048976 Uncertain "Secreted to blood" "No annotated function" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 38: Proximal tubular cells - Transmembrane transport" 5 "HPA048976: AB_2680582" "unprognostic (1.68e-1)" "unprognostic (3.06e-2)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (3.14e-2)" "unprognostic (4.62e-2)" "unprognostic (1.36e-1)" "unprognostic (4.14e-2)" "unprognostic (1.04e-1)" "unprognostic (4.40e-2)" "unprognostic (6.77e-4)" "unprognostic (6.73e-2)" "unprognostic (4.58e-2)" "unprognostic (2.06e-1)" "unprognostic (9.03e-4)" "unprognostic (1.52e-1)" "unprognostic (2.53e-2)" CLEC18B MRCL2 ENSG00000140839 "C-type lectin domain family 18 member B" Q6UXF7 16 74408631-74421478 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "kidney: 31.0" "Group enriched" "Detected in some" 11 "Proximal tubular cells: 32.2;Sertoli cells: 13.6" "Cancer enhanced" "Detected in some" "glioma: 2.7;renal cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" HPA048976 Uncertain "Secreted to blood" "No annotated function" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 54: Immune cells - T cell receptor" "Cluster 11: Neuronal - Sensory perception" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA048976: AB_2680582" "unprognostic (5.69e-2)" "unprognostic (1.46e-1)" "unprognostic (5.30e-3)" "unprognostic (9.37e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (7.15e-2)" "unprognostic (7.51e-2)" "unprognostic (4.49e-3)" "unprognostic (2.17e-1)" "unprognostic (2.28e-1)" "unprognostic (9.91e-2)" "unprognostic (3.58e-2)" "unprognostic (1.42e-2)" "unprognostic (2.31e-2)" "unprognostic (5.87e-2)" "unprognostic (5.43e-2)" "unprognostic (4.27e-2)" CLEC18C "MGC34761, MRCL3" ENSG00000157335 "C-type lectin domain family 18 member C" Q8NCF0 16 70173322-70187361 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "kidney: 17.3" "Cell type enriched" "Detected in some" 12 "Proximal tubular cells: 21.9" "Cancer enriched" "Detected in single" 9 "renal cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "lung cancer: 4.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" HPA048976 Uncertain "Secreted to blood" "No annotated function" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 15: Non-specific - Transcription" "Cluster 11: Neuronal - Sensory perception" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA048976: AB_2680582" "unprognostic (3.90e-1)" "unprognostic (3.03e-1)" "unprognostic (1.20e-4)" "unprognostic (5.55e-2)" "unprognostic (5.72e-3)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (3.79e-2)" "unprognostic (3.61e-3)" "unprognostic (6.98e-2)" CLEC19A ENSG00000261210 "C-type lectin domain containing 19A" Q6UXS0 16 19285731-19322145 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.3" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.6;Hofbauer cells: 1.4;Microglial cells: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Secreted in brain" "No annotated function" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Macrophages - Innate immune response" 1 "unprognostic (3.19e-1)" "unprognostic (3.72e-1)" "unprognostic (1.11e-1)" "unprognostic (1.82e-2)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" CLEC2B "AICL, CLECSF2, HP10085" ENSG00000110852 "C-type lectin domain family 2 member B" Q92478 12 9852369-9869386 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 111.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 355.9;monocytes: 704.6;NK-cells: 407.1;T-cells: 307.5" "Cancer enhanced" "Detected in all" "cervical cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 222.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 37.0" "Low region specificity" "Detected in all" HPA008194 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "HPA008194: AB_1078533" "unprognostic (3.14e-2)" "unprognostic (4.27e-2)" "unprognostic (2.14e-2)" "unprognostic (9.69e-3)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" "unprognostic (5.99e-2)" "unprognostic (4.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.58e-1)" "unprognostic (1.15e-3)" "unprognostic (3.50e-1)" "prognostic unfavorable (5.64e-13)" "unprognostic (8.09e-2)" "unprognostic (7.12e-3)" "unprognostic (5.70e-2)" "unprognostic (2.79e-1)" CLEC3A CLECSF1 ENSG00000166509 "C-type lectin domain family 3 member A" O75596 16 78022515-78066761 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 9.0;urinary bladder: 5.6" "Cell type enhanced" "Detected in single" "Horizontal cells: 1.3" "Cancer enriched" "Detected in some" 102 "breast cancer: 78.5" "Region enriched" "Detected in some" 5 "midbrain: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "breast cancer: 29.9;cervical cancer: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA051511 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "HPA051511: AB_2681514" "prognostic unfavorable (1.61e-4)" "unprognostic (1.60e-1)" "unprognostic (2.42e-1)" "unprognostic (1.25e-1)" "unprognostic (4.95e-2)" "unprognostic (3.80e-2)" CLEC3B "TN, TNA" ENSG00000163815 "C-type lectin domain family 3 member B" P05452 3 45001548-45036071 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 406.8" "Cell type enhanced" "Detected in some" "Adipocytes: 37.5;Endothelial cells: 35.2;Fibroblasts: 79.6;Leydig cells: 17.6;Microglial cells: 66.2;Smooth muscle cells: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 16.1" "Liver - Sinusoid Endothelial cells, Liver - Vascular Endothelial cells, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002582, HPA034794" Approved "Secreted to blood" "No annotated function" NA NA 6540000000 25000000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "CAB002582: AB_564027, HPA034794: AB_2674332" "unprognostic (2.04e-1)" "unprognostic (1.80e-3)" "unprognostic (2.58e-1)" "unprognostic (4.57e-2)" "unprognostic (7.75e-2)" "prognostic favorable (1.53e-4)" "prognostic favorable (9.99e-9)" "unprognostic (1.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.02e-1)" "prognostic favorable (5.68e-4)" "unprognostic (9.33e-2)" "unprognostic (2.39e-2)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.21e-2)" CLEC4M "CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, LSIGN" ENSG00000104938 "C-type lectin domain family 4 member M" Q9H2X3 19 7763210-7769605 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 60.8;lymphoid tissue: 16.0" "Cell type enhanced" "Detected in some" "Endothelial cells: 21.8;Fibroblasts: 41.6;Granulosa cells: 32.9;Kupffer cells: 19.0;Sertoli cells: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033689, CAB033691, HPA042661" Supported "Intracellular and membrane" Receptor NA NA 3400000 "Cluster 31: Liver - Plasma proteins" "Cluster 45: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "CAB033689: AB_831088, CAB033691: AB_2081354, HPA042661: AB_2678101" "unprognostic (1.56e-1)" "unprognostic (3.03e-1)" "unprognostic (1.00e-1)" "unprognostic (1.71e-2)" "unprognostic (1.26e-2)" "unprognostic (1.64e-1)" "unprognostic (6.58e-2)" "unprognostic (1.27e-1)" "unprognostic (4.58e-3)" "unprognostic (4.60e-2)" "unprognostic (5.15e-2)" "unprognostic (1.43e-1)" CLN5 ENSG00000102805 "CLN5 intracellular trafficking protein" O75503 13 76990660-77019143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 154.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041788 Approved "Intracellular and membrane" "No annotated function" NA NA 470000 "Cluster 25: Non-specific - Unknown function" "Cluster 51: Thyroid gland - Unknown function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "HPA041788: AB_10962726" "unprognostic (1.19e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.02e-1)" "unprognostic (9.82e-2)" "unprognostic (2.07e-3)" "unprognostic (3.41e-1)" "unprognostic (7.80e-2)" "unprognostic (2.29e-1)" "unprognostic (2.90e-1)" "unprognostic (6.98e-2)" "unprognostic (2.65e-1)" "prognostic favorable (1.52e-9)" "unprognostic (2.35e-1)" "unprognostic (7.04e-2)" "unprognostic (5.64e-2)" "unprognostic (8.15e-2)" CLPS ENSG00000137392 Colipase P04118 6 35794982-35797344 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Digestion, Lipid degradation, Lipid metabolism" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 3971 "pancreas: 253763.2" "Cell type enriched" "Detected in some" 59 "Exocrine glandular cells: 10593.3" "Cancer enriched" "Detected in many" 188 "pancreatic cancer: 1726.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "breast cancer: 2.1" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA010512 Enhanced "Secreted to digestive system" Other NA NA 1600000 "Cluster 15: Pancreas - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA010512: AB_1846979" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.12e-3)" "unprognostic (2.47e-1)" "unprognostic (1.33e-1)" "unprognostic (1.61e-1)" CLPSL1 "C6orf127, dJ510O8.6" ENSG00000204140 "Colipase like 1" A2RUU4 6 35781019-35793675 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 91 "epididymis: 592.0;pancreas: 173.3" "Cell type enriched" "Detected in some" 9 "Exocrine glandular cells: 27.9" "Group enriched" "Detected in some" 6 "breast cancer: 3.6;cervical cancer: 1.0;endometrial cancer: 2.8;ovarian cancer: 1.8;pancreatic cancer: 3.4" "Group enriched" "Detected in some" 4 "basal ganglia: 1.8;cerebral cortex: 5.5;hippocampal formation: 4.0;white matter: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "breast cancer: 8.1" "Breast - Breast glandular cells" HPA073155 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA073155: AB_2686576" "unprognostic (7.97e-2)" "unprognostic (1.58e-1)" "unprognostic (4.75e-1)" "unprognostic (2.54e-1)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.60e-2)" "unprognostic (7.06e-3)" CLPSL2 "C6orf126, dJ510O8.5, UNQ3045" ENSG00000196748 "Colipase like 2" Q6UWE3 6 35776594-35779552 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "epididymis: 518.4" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 2.4;Breast glandular cells: 2.9;Breast myoepithelial cells: 1.2;Exocrine glandular cells: 4.4;Pancreatic endocrine cells: 1.7;Spermatogonia: 1.9" "Cancer enhanced" "Detected in some" "breast cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.7" "Breast - Breast glandular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043460, HPA051655" Approved Approved Vesicles "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 Vesicles "HPA043460: , HPA051655: " "unprognostic (2.38e-1)" "unprognostic (3.65e-1)" "unprognostic (6.39e-3)" "unprognostic (9.38e-2)" "unprognostic (4.03e-2)" "unprognostic (2.47e-1)" "unprognostic (4.85e-3)" "unprognostic (8.69e-2)" "unprognostic (3.17e-2)" "unprognostic (3.95e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-1)" "unprognostic (2.37e-1)" CLPX ENSG00000166855 "Caseinolytic mitochondrial matrix peptidase chaperone subunit X" O76031 15 65148219-65185342 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 251.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040262, HPA048199" Approved Supported Nucleoplasm,Mitochondria,Cytosol "Intracellular and membrane" Other NA NA 65000 "Cluster 24: Non-specific - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 36: Late spermatids - Unknown function" Mitochondria "Nucleoplasm, Cytosol" "HPA040262: AB_10793961, HPA048199: AB_2680312" "unprognostic (2.78e-1)" "unprognostic (6.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.69e-2)" "unprognostic (2.00e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-3)" "unprognostic (2.64e-1)" "unprognostic (3.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.53e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.93e-9)" "unprognostic (1.76e-1)" "unprognostic (2.64e-1)" "unprognostic (5.95e-2)" "unprognostic (3.50e-2)" CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 9442.3" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 3199.0;Cholangiocytes: 2558.4;Collecting duct cells: 3117.6;Hepatocytes: 3758.6;Muller glia cells: 6791.7;Secretory cells: 6049.9" "Cancer enhanced" "Detected in all" "glioma: 1485.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 773.3" "Lineage enriched" "Detected in all" 33 "granulocytes: 773.3" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983, CAB080180" Enhanced Supported Cytosol "Secreted to blood" "Complement pathway" NA NA 169000000000 29000000000 "Cluster 41: Basophils - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 10: Muller glia cells - Visual perception" 8 Cytosol "CAB016253: AB_673562, CAB080180: , HPA000572: AB_1078539, HPA075983: " "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.74e-2)" "unprognostic (5.59e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-2)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.66e-5)" "unprognostic (5.29e-2)" CLUL1 ENSG00000079101 "Clusterin like 1" Q15846 18 596988-650334 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "retina: 288.9" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 322.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "CAB025264, HPA075240" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA 11000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 76: Retina - Visual perception" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" "Endoplasmic reticulum" "Plasma membrane" "CAB025264: , HPA075240: AB_2732286" "unprognostic (1.75e-2)" "unprognostic (9.15e-2)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (7.81e-3)" "unprognostic (3.00e-3)" "unprognostic (1.96e-1)" "unprognostic (2.97e-3)" "unprognostic (8.38e-3)" "unprognostic (3.76e-2)" "unprognostic (4.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.36e-4)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" "unprognostic (1.29e-3)" "unprognostic (2.37e-2)" CMA1 ENSG00000092009 "Chymase 1" P23946 14 24505353-24508265 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 17.8" "Cell type enriched" "Detected in some" 39 "granulocytes: 68.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.9" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000363, HPA052634" Enhanced Supported "Cytosol,Cytoplasmic bodies" "Secreted to blood" Enzyme NA NA 3000000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 39: Astrocytes - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 30: Granulocytes - Unknown function" "Cytoplasmic bodies" Cytosol "CAB000363: AB_2083616, HPA052634: AB_2681892" "unprognostic (1.37e-1)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" "unprognostic (7.07e-3)" "unprognostic (1.48e-2)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.21e-1)" "unprognostic (8.91e-3)" "unprognostic (4.19e-3)" "unprognostic (1.29e-4)" "unprognostic (2.52e-3)" "unprognostic (7.78e-2)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" CMPK1 "CMPK, UMP-CMPK" ENSG00000162368 "Cytidine/uridine monophosphate kinase 1" P30085 1 47333790-47394866 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053730, HPA058604" Approved Supported Nucleoplasm "Intracellular and membrane" Enzyme NA NA 1400000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Stomach - Proteolysis" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 64: Non-specific - Ribosome" Nucleoplasm "HPA053730: AB_2682244, HPA058604: AB_2683773" "unprognostic (2.16e-2)" "unprognostic (1.16e-1)" "unprognostic (9.39e-3)" "unprognostic (1.18e-1)" "unprognostic (1.09e-3)" "unprognostic (1.50e-2)" "unprognostic (1.59e-2)" "unprognostic (9.88e-2)" "unprognostic (5.80e-2)" "unprognostic (2.90e-2)" "unprognostic (1.71e-2)" "unprognostic (2.61e-1)" "unprognostic (1.28e-2)" "unprognostic (2.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-3)" "unprognostic (7.36e-2)" CNBD1 FLJ35802 ENSG00000176571 "Cyclic nucleotide binding domain containing 1" Q8NA66 8 86866415-87615219 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.9" "Group enriched" "Detected in some" 9 "Early spermatids: 180.1;Late spermatids: 101.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025037, HPA027469, HPA027786" Uncertain "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 18: Early spermatids - Unknown function" "HPA025037: AB_10794318, HPA027469: AB_10599492, HPA027786: AB_10600231" "unprognostic (1.89e-1)" CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534500-74587212 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 154.3" "Cell type enriched" "Detected in some" 11 "Oligodendrocytes: 336.5" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008933, HPA073283" Enhanced "Secreted to blood" Enzyme NA NA 2100000000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 51: Oligodendrocytes - Unknown function" "HPA008933: AB_1847033, HPA073283: " "unprognostic (7.43e-3)" "unprognostic (6.00e-2)" "unprognostic (8.55e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (6.90e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" CNMD "BRICD3, CHM-I, CHM1, LECT1, MYETS1" ENSG00000136110 Chondromodulin O75829 13 52703264-52739820 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 6.4;choroid plexus: 12.2;retina: 8.1;salivary gland: 6.5;thyroid gland: 3.2" "Cell type enriched" "Detected in some" 6 "Muller glia cells: 84.1" "Group enriched" "Detected in many" 5 "glioma: 1.5;lung cancer: 6.0;testis cancer: 5.8;thyroid cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.1;testis cancer: 1.2" "Pancreas - Beta cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010510 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA 9500 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Muller glia cells - Visual perception" "HPA010510: AB_10602021" "unprognostic (7.52e-3)" "unprognostic (1.34e-1)" "unprognostic (7.36e-2)" "unprognostic (1.45e-2)" "unprognostic (1.15e-1)" "unprognostic (3.22e-1)" "unprognostic (2.84e-2)" "unprognostic (2.63e-2)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (1.96e-1)" CNOT9 "CAF40, CT129, RCD1, RCD1+, RQCD1" ENSG00000144580 "CCR4-NOT transcription complex subunit 9" Q92600 2 218568580-218597080 "Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046622 Approved Approved "Cytoplasmic bodies" "Intracellular and membrane" Transcription NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Monocytes - Innate immune response" 2 "Cytoplasmic bodies" "HPA046622: AB_10962694" "unprognostic (7.70e-2)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.58e-2)" "unprognostic (1.34e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (8.41e-9)" "unprognostic (8.08e-3)" "unprognostic (1.91e-3)" "unprognostic (1.53e-2)" "unprognostic (7.02e-2)" "unprognostic (6.89e-2)" "prognostic unfavorable (4.69e-9)" "unprognostic (1.87e-2)" "unprognostic (2.38e-2)" "unprognostic (2.05e-1)" "unprognostic (4.67e-2)" CNPY2 "HP10390, TMEM4, ZSIG9" ENSG00000257727 "Canopy FGF signaling regulator 2" Q9Y2B0 12 56309842-56316119 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 513.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038465, HPA038466" Supported Supported Cytosol "Intracellular and membrane" "No annotated function" NA NA 220000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 4: Extravillous trophoblasts - Unknown function" 2 Cytosol "HPA038465: AB_10967609, HPA038466: AB_10672646" "unprognostic (3.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.49e-1)" "unprognostic (2.46e-2)" "unprognostic (4.33e-2)" "unprognostic (2.20e-1)" "unprognostic (1.17e-3)" "unprognostic (1.46e-1)" "unprognostic (7.68e-2)" "unprognostic (2.04e-3)" "prognostic favorable (8.37e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.32e-8)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "unprognostic (2.67e-2)" "unprognostic (5.06e-2)" CNPY3 "CAG4A, TNRC5" ENSG00000137161 "Canopy FGF signaling regulator 3" Q9BT09 6 42929480-42939294 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" Chaperone "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 270.3;Extravillous trophoblasts: 204.8;Hofbauer cells: 306.8;Kupffer cells: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016560 Uncertain "Intracellular and membrane" Immunity NA NA 4100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 29: Monocytes - Innate immune response" 9 "HPA016560: AB_1858173" "unprognostic (5.26e-3)" "unprognostic (6.63e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (8.15e-2)" "unprognostic (3.12e-1)" "unprognostic (1.79e-1)" "unprognostic (5.70e-3)" "unprognostic (5.11e-2)" "unprognostic (4.77e-2)" "unprognostic (1.94e-2)" "unprognostic (2.26e-3)" "unprognostic (4.54e-2)" "prognostic unfavorable (9.85e-6)" "unprognostic (2.34e-1)" "unprognostic (1.93e-2)" "unprognostic (2.21e-2)" "unprognostic (2.98e-3)" CNPY4 "MGC40499, PRAT4B" ENSG00000166997 "Canopy FGF signaling regulator 4" Q8N129 7 100119634-100125508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.5;Leydig cells: 34.1;Peritubular cells: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014166, HPA025240" Uncertain Approved Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 59: Fallopian tube - Tissue development" "Cluster 25: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 50: Connective tissue cells - ECM organization" 1 Vesicles "HPA014166: AB_1853895, HPA025240: AB_2082630" "unprognostic (9.64e-2)" "unprognostic (1.59e-2)" "unprognostic (4.09e-3)" "unprognostic (8.44e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.16e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (6.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (1.35e-2)" CNTN1 "F3, GP135" ENSG00000018236 "Contactin 1" Q12860 12 40692439-41072415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 125.0" "Group enriched" "Detected in many" 5 "Astrocytes: 724.5;Excitatory neurons: 816.4;Inhibitory neurons: 669.1;Oligodendrocyte precursor cells: 958.4" "Cancer enhanced" "Detected in many" "glioma: 17.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.5" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 6 "Gallbladder cancer: 245.7" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025200, HPA070467" Enhanced Approved "Intracellular and membrane" "Cell adhesion" NA NA 450000000 "Cluster 22: Eosinophils - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 2 "CAB025200: , HPA070467: AB_2732156" "unprognostic (3.18e-2)" "unprognostic (5.96e-3)" "unprognostic (3.66e-2)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (9.13e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.32e-2)" "unprognostic (8.15e-4)" "unprognostic (6.98e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (3.75e-4)" CNTN2 "AXT, TAG-1, TAX, TAX1" ENSG00000184144 "Contactin 2" Q02246 1 205042937-205078289 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cell adhesion" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "brain: 158.9" "Cell type enriched" "Detected in some" 12 "Oligodendrocytes: 312.2" "Cancer enriched" "Detected in some" 9 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 5.8" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001397, HPA012497" Approved "Secreted in brain" "Cell adhesion" NA NA 58000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" 2 "HPA001397: AB_1847146, HPA012497: AB_1847147" "unprognostic (1.90e-1)" "unprognostic (1.86e-1)" "unprognostic (2.87e-2)" "unprognostic (4.52e-3)" "unprognostic (2.98e-2)" "unprognostic (5.96e-2)" "unprognostic (3.25e-1)" "unprognostic (1.43e-2)" "unprognostic (8.56e-2)" "unprognostic (2.40e-1)" "unprognostic (3.44e-3)" "unprognostic (5.62e-2)" "unprognostic (1.73e-7)" "unprognostic (9.82e-3)" "unprognostic (1.19e-1)" "unprognostic (3.35e-2)" "unprognostic (3.07e-2)" CNTN3 "BIG-1, PANG" ENSG00000113805 "Contactin 3" Q9P232 3 74262568-74614659 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 10 "Excitatory neurons: 265.1;Inhibitory neurons: 186.5;Oligodendrocyte precursor cells: 214.6" "Cancer enhanced" "Detected in many" "prostate cancer: 2.9" "Region enriched" "Detected in all" 28 "cerebral cortex: 1682.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003341 Approved "Intracellular and membrane" "Cell adhesion" NA NA 130000000 "Cluster 64: Neuronal - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" "HPA003341: AB_1078556" "unprognostic (1.66e-2)" "unprognostic (1.86e-1)" "unprognostic (2.35e-3)" "unprognostic (9.86e-2)" "unprognostic (1.82e-2)" "unprognostic (1.94e-5)" "unprognostic (4.25e-2)" "unprognostic (2.13e-3)" "unprognostic (8.42e-2)" "unprognostic (3.85e-2)" "unprognostic (1.50e-1)" "unprognostic (7.25e-2)" "unprognostic (9.30e-7)" "unprognostic (4.23e-2)" "unprognostic (1.63e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" CNTN4 BIG-2 ENSG00000144619 "Contactin 4" Q8IWV2 3 2098813-3057959 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 21.8;retina: 19.2" "Cell type enhanced" "Detected in many" "Early spermatids: 484.0;Excitatory neurons: 928.6;Inhibitory neurons: 1004.1;Late spermatids: 183.8;Oligodendrocyte precursor cells: 233.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.2;Rhabdoid: 5.2" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "Cell adhesion" NA NA 170000000 "Cluster 74: Spermatids - Flagellum assembly" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "unprognostic (1.64e-1)" "unprognostic (7.17e-3)" "unprognostic (9.85e-2)" "unprognostic (5.75e-2)" "unprognostic (9.94e-2)" "unprognostic (1.33e-1)" "unprognostic (3.85e-1)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (2.60e-2)" "unprognostic (7.38e-3)" "unprognostic (2.41e-2)" "prognostic favorable (1.00e-4)" "unprognostic (1.22e-2)" "unprognostic (2.88e-2)" "unprognostic (2.10e-1)" "unprognostic (2.13e-1)" CNTN5 "hNB-2, NB-2" ENSG00000149972 "Contactin 5" O94779 11 99020949-100358885 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;placenta: 2.5;salivary gland: 2.0;thyroid gland: 1.9" "Group enriched" "Detected in some" 14 "Excitatory neurons: 938.0;Inhibitory neurons: 2198.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.5" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Beta cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039492, HPA041223" Approved "Intracellular and membrane" "Cell adhesion" NA NA 480000 "Cluster 34: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 65: Neurons - Synaptic function" "HPA039492: AB_10795108, HPA041223: AB_10794549" "unprognostic (2.09e-2)" "unprognostic (3.40e-1)" "unprognostic (8.99e-3)" "unprognostic (4.20e-2)" "unprognostic (6.51e-5)" "unprognostic (3.85e-2)" "unprognostic (9.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.02e-2)" "unprognostic (8.72e-2)" "unprognostic (5.48e-3)" "unprognostic (1.81e-2)" "unprognostic (1.76e-1)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" CNTNAP3 "CASPR3, CNTNAP3A, FLJ14195, KIAA1714" ENSG00000106714 "Contactin associated protein family member 3" Q9BZ76 9 39064710-39288315 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 99.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "neutrophil: 7.4" "Lineage enriched" "Detected in single" 75 "granulocytes: 7.4" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" HPA047731 Uncertain "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 8: Neurons - Neuronal signaling" "HPA047731: AB_2680137" "unprognostic (9.06e-3)" "unprognostic (3.07e-2)" "unprognostic (5.74e-2)" "unprognostic (7.89e-2)" "unprognostic (7.03e-2)" "unprognostic (2.33e-3)" "unprognostic (4.58e-2)" "unprognostic (1.34e-2)" "unprognostic (1.51e-1)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (3.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.15e-2)" "unprognostic (1.20e-1)" "unprognostic (1.95e-3)" "unprognostic (1.93e-3)" COASY "DPCK, NBP, PPAT" ENSG00000068120 "Coenzyme A synthase" Q13057 17 42561467-42566277 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Coenzyme A biosynthesis" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022875, HPA022912, HPA023273" Approved "Intracellular and membrane" Enzyme NA NA 20000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 2 "HPA022875: AB_1847066, HPA022912: AB_1847067, HPA023273: AB_1847068" "unprognostic (2.83e-1)" "unprognostic (8.35e-2)" "unprognostic (1.81e-1)" "prognostic favorable (2.15e-4)" "unprognostic (1.01e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (7.54e-5)" "unprognostic (4.06e-2)" "unprognostic (3.36e-2)" "unprognostic (2.50e-2)" "unprognostic (1.50e-1)" "unprognostic (7.83e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (5.55e-1)" "unprognostic (1.62e-1)" "unprognostic (2.16e-1)" COCH "COCH-5B2, DFNA31, DFNA9" ENSG00000100473 Cochlin O43405 14 30874514-30895065 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 486.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 36.2;Horizontal cells: 32.7;Oocytes: 64.0;Spermatocytes: 29.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 151.3" "Group enriched" "Detected in some" 12 "memory B-cell: 38.4;naive B-cell: 17.8" "Lineage enriched" "Detected in many" 17 "B-cells: 38.4" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 23.2;basal ganglia: 66.7;cerebral cortex: 17.2;hippocampal formation: 16.6" HPA065086 Supported Vesicles "Secreted in other tissues" Other NA NA 160000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 15: Pancreas - Proteolysis" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA065086: " "unprognostic (8.36e-3)" "unprognostic (2.51e-2)" "unprognostic (8.61e-2)" "unprognostic (1.64e-2)" "unprognostic (6.48e-2)" "unprognostic (6.53e-2)" "unprognostic (9.61e-2)" "unprognostic (4.03e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.27e-2)" "unprognostic (2.91e-3)" "unprognostic (5.42e-3)" "unprognostic (3.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.72e-1)" COL10A1 ENSG00000123500 "Collagen type X alpha 1 chain" Q03692 6 116118909-116158747 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 8.6;ovary: 5.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 25.8;Inhibitory neurons: 6.0;Microglial cells: 8.1;Oligodendrocytes: 25.9" "Cancer enhanced" "Detected in many" "breast cancer: 42.8;pancreatic cancer: 51.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.9;thyroid cancer: 3.3" "Low region specificity" "Detected in many" HPA053268 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA 160000 "Cluster 68: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" 7 "Endoplasmic reticulum" "HPA053268: " "unprognostic (3.83e-2)" "unprognostic (6.81e-2)" "unprognostic (7.20e-2)" "unprognostic (7.45e-3)" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (3.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" "unprognostic (4.37e-2)" "unprognostic (7.03e-2)" "unprognostic (1.38e-11)" "unprognostic (2.16e-3)" "unprognostic (7.22e-2)" "unprognostic (3.60e-1)" "unprognostic (2.06e-3)" COL11A1 "CO11A1, COLL6, DFNA37, STL2" ENSG00000060718 "Collagen type XI alpha 1 chain" P12107 1 102876467-103108872 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 19.5;retina: 9.3" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 523.1" "Cancer enhanced" "Detected in many" "breast cancer: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 252.9" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058335 Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" No No 640000 "Cluster 34: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Endoplasmic reticulum" "HPA058335: AB_2683682" "unprognostic (2.60e-3)" "unprognostic (6.61e-4)" "unprognostic (9.58e-2)" "unprognostic (5.06e-5)" "unprognostic (2.83e-1)" "unprognostic (2.85e-2)" "unprognostic (6.03e-3)" "unprognostic (2.23e-3)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (1.94e-2)" "unprognostic (3.01e-12)" "unprognostic (1.27e-2)" "unprognostic (3.53e-1)" "unprognostic (3.54e-2)" "unprognostic (2.32e-2)" COL11A2 "DFNA13, DFNB53, HKE5" ENSG00000204248 "Collagen type XI alpha 2 chain" P13942 6 33162681-33192499 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 14.9;pituitary gland: 22.8;testis: 7.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Early spermatids: 7.1;Horizontal cells: 5.7;Late spermatids: 5.7;Muller glia cells: 5.0;Oligodendrocytes: 6.2" "Cancer enriched" "Detected in many" 8 "melanoma: 13.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 2.7;skin cancer: 1.7" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 2100000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 6: Non-specific - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 21: Early spermatids - Spermatogenesis" 1 "unprognostic (4.62e-1)" "unprognostic (8.69e-2)" "unprognostic (1.65e-4)" "unprognostic (5.15e-3)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (1.04e-2)" "unprognostic (9.67e-2)" "unprognostic (2.05e-2)" "unprognostic (4.47e-2)" "unprognostic (1.22e-1)" "unprognostic (3.41e-3)" "unprognostic (2.26e-6)" "unprognostic (8.27e-2)" "unprognostic (2.17e-1)" "unprognostic (1.88e-1)" "unprognostic (5.96e-2)" COL12A1 COL12A1L ENSG00000111799 "Collagen type XII alpha 1 chain" Q99715 6 75084326-75206267 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 151.1;Endometrial stromal cells: 69.1;Fibroblasts: 131.8;Leydig cells: 67.2;Ovarian stromal cells: 98.7;Smooth muscle cells: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 39.2" "HPA009143, HPA010021" Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA 9100000 "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Vesicles Cytosol "HPA009143: AB_1847095, HPA010021: " "unprognostic (2.60e-2)" "unprognostic (2.80e-3)" "unprognostic (7.92e-2)" "unprognostic (8.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (3.47e-3)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "prognostic unfavorable (1.69e-9)" "unprognostic (1.03e-3)" "unprognostic (1.81e-1)" "unprognostic (3.16e-3)" "unprognostic (1.92e-2)" COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 146.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 99.7;Fibroblasts: 189.8;Granulosa cells: 103.2;Ovarian stromal cells: 53.5;Schwann cells: 65.2;Smooth muscle cells: 161.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Brain cancer: 24.1;colorectal cancer: 18.5;Sarcoma: 48.6;thyroid cancer: 18.0" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 3200000 "Cluster 62: Connective tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" COL15A1 ENSG00000204291 "Collagen type XV alpha 1 chain" P39059 9 98943179-99070792 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 221.6" "Cell type enhanced" "Detected in many" "Adipocytes: 292.9;Endometrial stromal cells: 98.0;Endothelial cells: 147.7;Fibroblasts: 163.4;Leydig cells: 324.7;Peritubular cells: 458.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 13.8;skin cancer: 14.8" "Adipose visceral - Endothelial cells, Colon - Smooth muscle cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skin - Fibroblast_1, Testis - Peritubular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "spinal cord: 56.0" "HPA017913, HPA017915" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "Developmental protein" NA NA 28000000 "Cluster 58: Placenta - Pregnancy" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA017913: AB_1847099, HPA017915: AB_1847100" "unprognostic (4.30e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-2)" "unprognostic (2.09e-1)" "unprognostic (1.09e-2)" "prognostic favorable (5.47e-4)" "unprognostic (3.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-3)" "unprognostic (3.66e-3)" "unprognostic (8.98e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (3.08e-4)" COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 180.2" "Cell type enhanced" "Detected in many" "Astrocytes: 103.4;Oligodendrocyte precursor cells: 58.5;Oligodendrocytes: 113.5;Ovarian stromal cells: 76.5;Peritubular cells: 90.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 57.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027235 Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" "Cell adhesion" NA NA 960000 "Cluster 62: Connective tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 6: Ovarian stromal cells - Transcription" "Golgi apparatus" Cytosol "HPA027235: AB_1847101" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (5.64e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (2.04e-1)" "unprognostic (4.48e-3)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (4.00e-9)" "unprognostic (9.62e-2)" "unprognostic (6.13e-2)" "unprognostic (4.60e-2)" "unprognostic (2.15e-2)" COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 564.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 670.0;Basal respiratory cells: 124.0;Basal squamous epithelial cells: 189.5;Breast myoepithelial cells: 95.4;Distal enterocytes: 135.2;Salivary duct cells: 114.7;Suprabasal keratinocytes: 155.0" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 200.6;head and neck cancer: 440.5" "Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in all" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA 32000 "Cluster 13: Skin - Cornification" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 6 "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 548.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 371.4;Smooth muscle cells: 244.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Liver - Hepatocytes, Prostate - Endothelial cells, Skin - Fibroblast_1" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA 290000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" COL19A1 ENSG00000082293 "Collagen type XIX alpha 1 chain" Q14993 6 69866556-70212468 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;lymphoid tissue: 3.1;urinary bladder: 2.1" "Cell type enhanced" "Detected in some" "B-cells: 29.3;Excitatory neurons: 64.2;Inhibitory neurons: 157.0;Oligodendrocyte precursor cells: 37.3;Skeletal myocytes: 209.8" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 218 "memory B-cell: 14.6;naive B-cell: 32.0" "Lineage enriched" "Detected in single" 299 "B-cells: 32.0" "Cancer enhanced" "Detected in some" "Sarcoma: 3.9;skin cancer: 10.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA042422 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "HPA042422: AB_10794798" "unprognostic (2.65e-2)" "unprognostic (2.55e-1)" "unprognostic (2.71e-1)" "unprognostic (9.24e-2)" "unprognostic (2.26e-2)" "unprognostic (6.20e-2)" "unprognostic (3.17e-1)" "unprognostic (1.10e-3)" "unprognostic (3.41e-1)" "unprognostic (1.28e-1)" "unprognostic (2.76e-1)" "unprognostic (1.62e-2)" "unprognostic (1.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.20e-1)" "unprognostic (3.35e-1)" "unprognostic (8.91e-2)" COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1284.0;gallbladder: 1170.7;ovary: 1172.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1832.0;Fibroblasts: 1713.3;Leydig cells: 547.1;Ovarian stromal cells: 435.9;Pancreatic endocrine cells: 1558.7;Smooth muscle cells: 617.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 1387.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 170.5" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA 80000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 22 "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" COL1A2 OI4 ENSG00000164692 "Collagen type I alpha 2 chain" P08123 7 94394895-94431227 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 1678.8;gallbladder: 1290.4;ovary: 1367.1;smooth muscle: 1307.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 699.6;Fibroblasts: 1831.0;Glandular and luminal cells: 445.8;Leydig cells: 980.2;Pancreatic endocrine cells: 492.4;Peritubular cells: 486.3;Smooth muscle cells: 570.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 1425.0;Sarcoma: 742.4" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 172.6" "CAB032650, HPA068464, HPA068494" Approved Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA 27000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 9 "Endoplasmic reticulum" "CAB032650: AB_2082039, HPA068464: , HPA068494: " "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.32e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-2)" "unprognostic (2.81e-1)" "unprognostic (5.15e-2)" "unprognostic (7.38e-3)" "unprognostic (2.01e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.35e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.31e-3)" COL20A1 KIAA1510 ENSG00000101203 "Collagen type XX alpha 1 chain" Q9P218 20 63293186-63334851 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 9.0;testis: 2.4" "Group enriched" "Detected in some" 7 "Oligodendrocyte precursor cells: 68.4;Spermatocytes: 20.5" "Cancer enriched" "Detected in single" 19 "glioma: 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 1.4" "Low region specificity" "Detected in many" HPA060109 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Golgi apparatus, Vesicles" "HPA060109: " "unprognostic (6.34e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "unprognostic (2.01e-1)" "unprognostic (5.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "unprognostic (1.70e-2)" "unprognostic (1.71e-1)" "unprognostic (2.89e-1)" "unprognostic (8.41e-7)" "unprognostic (7.85e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-2)" "unprognostic (1.16e-1)" COL21A1 ENSG00000124749 "Collagen type XXI alpha 1 chain" Q96P44 6 56056590-56394094 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.2;placenta: 27.4" "Cell type enhanced" "Detected in many" "Astrocytes: 63.2;Cardiomyocytes: 46.8;Extravillous trophoblasts: 86.7;Inhibitory neurons: 60.3;Schwann cells: 69.2;Skeletal myocytes: 38.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 9.0;prostate cancer: 9.2;Rhabdoid: 8.7;testis cancer: 10.3" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA031212 Supported Cytosol "Secreted to extracellular matrix" "No annotated function" NA NA 290000 "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" Cytosol "HPA031212: AB_10599941" "unprognostic (1.69e-1)" "unprognostic (4.53e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-1)" "unprognostic (1.21e-1)" "unprognostic (9.32e-3)" "unprognostic (6.84e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (5.29e-2)" "unprognostic (3.10e-1)" "unprognostic (1.26e-3)" "unprognostic (3.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-3)" COL22A1 ENSG00000169436 "Collagen type XXII alpha 1 chain" Q8NFW1 8 138588235-138914041 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 42.9" "Group enriched" "Detected in some" 5 "Early spermatids: 40.9;Excitatory neurons: 12.6;Late spermatids: 36.6;Muller glia cells: 21.0;Oocytes: 28.7" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA024830 Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" Vesicles "Endoplasmic reticulum" "HPA024830: AB_1847102" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (2.88e-2)" "unprognostic (4.19e-6)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.05e-2)" "unprognostic (5.57e-3)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.01e-1)" "unprognostic (9.24e-2)" "unprognostic (5.74e-2)" "unprognostic (3.62e-2)" "unprognostic (3.66e-15)" "unprognostic (2.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (1.09e-1)" COL24A1 ENSG00000171502 "Collagen type XXIV alpha 1 chain" Q17RW2 1 85729233-86156943 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 6.6;intestine: 6.5" "Cell type enriched" "Detected in some" 5 "Excitatory neurons: 161.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 2.7" "Lineage enriched" "Detected in single" 9 "dendritic cells: 2.7" "Cancer enhanced" "Detected in some" "Leukemia: 2.6;Myeloma: 4.1" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 52000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Neurons - Neuronal signaling" 1 "unprognostic (3.00e-1)" "unprognostic (6.19e-2)" "unprognostic (2.21e-2)" "unprognostic (6.76e-3)" "unprognostic (1.82e-3)" "unprognostic (2.45e-2)" "unprognostic (2.44e-5)" "unprognostic (1.37e-1)" "unprognostic (4.08e-2)" "unprognostic (6.59e-2)" "unprognostic (3.89e-2)" "unprognostic (1.46e-1)" "unprognostic (3.48e-6)" "unprognostic (2.79e-5)" "unprognostic (5.07e-1)" "unprognostic (1.19e-1)" "unprognostic (9.90e-2)" COL26A1 "EMI6, EMID2, Emu2" ENSG00000160963 "Collagen type XXVI alpha 1 chain" Q96A83 7 101362875-101559024 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 22.3" "Group enriched" "Detected in some" 7 "Excitatory neurons: 66.3;Inhibitory neurons: 17.7" "Group enriched" "Detected in many" 6 "endometrial cancer: 12.6;ovarian cancer: 5.7;prostate cancer: 4.6;testis cancer: 14.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 44 "plasmacytoid DC: 9.2" "Lineage enriched" "Detected in single" 44 "dendritic cells: 9.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 24.1;Rhabdoid: 54.3;Uterine cancer: 24.1" "Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027059 Approved Approved Vesicles "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA027059: AB_1848142" "unprognostic (5.94e-3)" "unprognostic (2.16e-2)" "unprognostic (2.19e-2)" "unprognostic (4.67e-2)" "unprognostic (1.66e-1)" "unprognostic (3.35e-1)" "prognostic favorable (2.32e-5)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.26e-3)" "unprognostic (1.78e-1)" "unprognostic (4.24e-3)" "unprognostic (3.60e-1)" "unprognostic (1.50e-1)" "unprognostic (7.48e-4)" "unprognostic (2.83e-3)" COL27A1 "FLJ11895, KIAA1870, MGC11337" ENSG00000196739 "Collagen type XXVII alpha 1 chain" Q8IZC6 9 114155537-114312511 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.5;cervix: 90.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 51.5;Extravillous trophoblasts: 90.2;Gastric mucus-secreting cells: 38.3;Melanocytes: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in some" "Region enriched" "Detected in all" 20 "cerebellum: 102.1" "HPA021884, HPA048471" Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA021884: AB_2670857, HPA048471: AB_2680407" "unprognostic (4.45e-2)" "unprognostic (3.27e-1)" "unprognostic (1.32e-1)" "unprognostic (5.00e-2)" "prognostic unfavorable (7.11e-4)" "unprognostic (4.13e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (6.25e-2)" "unprognostic (1.71e-1)" "unprognostic (1.09e-3)" "unprognostic (3.31e-1)" "unprognostic (3.41e-2)" "unprognostic (2.97e-2)" "unprognostic (9.48e-2)" "unprognostic (6.21e-3)" "unprognostic (3.50e-3)" COL28A1 ENSG00000215018 "Collagen type XXVIII alpha 1 chain" Q2UY09 7 7356203-7535873 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.8" "Cell type enriched" "Detected in many" 5 "Schwann cells: 189.4" "Cancer enhanced" "Detected in many" "glioma: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 10.2" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Thyroid - Fibroblasts" "Region enriched" "Detected in single" 8 "olfactory bulb: 3.6" "Region enriched" "Detected in some" 31 "spinal cord: 44.1" "HPA043844, HPA060468" Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Nucleoplasm, Cytosol" "HPA043844: AB_2732508, HPA060468: AB_2684288" "unprognostic (6.28e-2)" "unprognostic (2.90e-2)" "unprognostic (1.28e-1)" "unprognostic (8.71e-3)" "unprognostic (1.89e-2)" "unprognostic (5.63e-3)" "unprognostic (2.61e-2)" "unprognostic (7.58e-2)" "unprognostic (2.72e-2)" "unprognostic (7.69e-2)" "unprognostic (3.90e-3)" "unprognostic (2.33e-2)" "unprognostic (3.45e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (2.48e-3)" "unprognostic (3.09e-2)" COL2A1 "AOM, SEDC, STL1" ENSG00000139219 "Collagen type II alpha 1 chain" P02458 12 47972967-48004554 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 18.6;pituitary gland: 8.9;retina: 5.4;stomach 1: 12.2" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 6.6;Early spermatids: 11.0;Enteroendocrine cells: 27.4;Granulosa cells: 9.7;Horizontal cells: 24.5;Late spermatids: 11.5;Muller glia cells: 21.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "liver cancer: 78.5" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002214, HPA055753" Approved Approved Nucleoplasm "Secreted to extracellular matrix" "No annotated function" No NA 1400000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 34: Testis cancer - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" Nucleoplasm "CAB002214: AB_563666, HPA055753: AB_2682908" "unprognostic (7.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.58e-1)" "unprognostic (3.44e-1)" "unprognostic (2.88e-2)" "unprognostic (3.08e-2)" "unprognostic (8.63e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (1.31e-4)" "unprognostic (2.64e-1)" "unprognostic (3.44e-3)" "unprognostic (1.89e-1)" "unprognostic (2.93e-1)" "unprognostic (2.07e-1)" "unprognostic (1.02e-1)" COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2284.1;gallbladder: 2022.4;placenta: 1914.8;smooth muscle: 2059.5" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 2579.5;Fibroblasts: 1454.9;Smooth muscle cells: 696.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "cerebral cortex: 21.6;choroid plexus: 22.8;thalamus: 22.8;white matter: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 1300.8;Sarcoma: 607.6;testis cancer: 879.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 74.6" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA 32000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" COL4A1 ENSG00000187498 "Collagen type IV alpha 1 chain" P02462 13 110148963-110307157 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 870.3" "Cell type enhanced" "Detected in many" "Adipocytes: 397.7;Endometrial stromal cells: 310.6;Endothelial cells: 227.5;Extravillous trophoblasts: 786.7;Fibroblasts: 292.6;Sertoli cells: 225.7;Smooth muscle cells: 412.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 215.6" "Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001695 Approved "Secreted to extracellular matrix" "Developmental protein" NA NA 75000 "Cluster 58: Placenta - Pregnancy" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "CAB001695: " "unprognostic (3.82e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (2.27e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-3)" "unprognostic (1.06e-2)" "unprognostic (9.79e-2)" "unprognostic (1.73e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.30e-7)" "unprognostic (1.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-2)" COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 458.1" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Alveolar cells type 1: 249.4;Endometrial stromal cells: 316.7;Extravillous trophoblasts: 627.8;Fibroblasts: 228.7;Smooth muscle cells: 392.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 278.9" "Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 2700000 "Cluster 62: Connective tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" 1 Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" COL4A3 ENSG00000169031 "Collagen type IV alpha 3 chain" Q01955 2 227164624-227314792 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 29.7;retina: 35.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 52.7;Bipolar cells: 67.7;Collecting duct cells: 44.7;Cone photoreceptor cells: 190.3;Granulosa cells: 79.6;Muller glia cells: 110.7;Oligodendrocyte precursor cells: 79.7;Skeletal myocytes: 64.4" "Group enriched" "Detected in some" 6 "lung cancer: 1.7;renal cancer: 3.0;thyroid cancer: 5.0" "Region enhanced" "Detected in all" "choroid plexus: 45.6" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 7 "B-cells: 1.0" "Cancer enhanced" "Detected in some" "Myeloma: 7.4" "Lung - Alveolar cells type 1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042064 Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 10: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA042064: AB_10794410" "unprognostic (4.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-6)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (1.84e-2)" "unprognostic (7.07e-3)" "unprognostic (2.30e-1)" "unprognostic (9.09e-3)" "unprognostic (9.30e-2)" "unprognostic (3.02e-2)" "prognostic favorable (2.51e-7)" "unprognostic (1.78e-1)" "unprognostic (3.10e-2)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 103.2;Collecting duct cells: 40.8;Cone photoreceptor cells: 42.5;Granulosa cells: 64.4;Muller glia cells: 72.7;Oligodendrocyte precursor cells: 51.9;Skeletal myocytes: 53.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.1" "Region enhanced" "Detected in all" "choroid plexus: 31.8" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.7" "Lineage enriched" "Detected in single" 5 "B-cells: 2.7" "Cancer enhanced" "Detected in many" "Myeloma: 9.1" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 23: Non-specific - Cellular respiration" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Muller glia cells - Visual perception" "unprognostic (7.31e-2)" "unprognostic (7.56e-2)" "unprognostic (6.65e-2)" "unprognostic (4.88e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (8.50e-3)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "prognostic favorable (2.30e-13)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 664.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 60.5" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (2.58e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-2)" "unprognostic (7.27e-2)" "unprognostic (2.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.06e-1)" COL4A6 ENSG00000197565 "Collagen type IV alpha 6 chain" Q14031 X 108155607-108439497 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.5;urinary bladder: 39.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 15.6;Basal respiratory cells: 16.2;Cardiomyocytes: 10.0;Microglial cells: 8.1;Peritubular cells: 10.4;Smooth muscle cells: 8.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 16.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA065393 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 "Endoplasmic reticulum" "HPA065393: AB_2685483" "unprognostic (8.47e-3)" "unprognostic (4.50e-3)" "unprognostic (9.75e-3)" "unprognostic (9.80e-3)" "unprognostic (1.18e-1)" "unprognostic (5.99e-2)" "unprognostic (1.78e-2)" "unprognostic (3.78e-2)" "unprognostic (1.72e-1)" "unprognostic (9.84e-2)" "unprognostic (1.40e-2)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.32e-2)" "unprognostic (2.06e-1)" "unprognostic (8.54e-3)" "unprognostic (3.51e-1)" COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 124.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 127.3;Fibroblasts: 123.9;Leydig cells: 60.4;Pancreatic endocrine cells: 61.1;Schwann cells: 50.2;Smooth muscle cells: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 229.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" Other No No 15000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 5 Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 172.8;Excitatory neurons: 179.1;Fibroblasts: 158.8;Smooth muscle cells: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 482.1;testis cancer: 343.6" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 820000 "Cluster 62: Connective tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Astrocytes: 484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 9.2;Sarcoma: 8.1;skin cancer: 7.1" "Breast - Adipocytes (Breast), Kidney - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA 330000 "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 47: Astrocytes - Unknown function" "Plasma membrane" "HPA041695: , HPA048256: AB_2680330" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (6.84e-3)" "unprognostic (3.01e-1)" "unprognostic (7.47e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.17e-8)" "unprognostic (3.25e-2)" "unprognostic (7.31e-3)" "unprognostic (6.00e-2)" "prognostic unfavorable (6.87e-5)" COL6A1 ENSG00000142156 "Collagen type VI alpha 1 chain" P12109 21 45981770-46005050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 770.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 529.6;Fibroblasts: 726.0;Leydig cells: 341.2;Ovarian stromal cells: 267.7;Peritubular cells: 233.8;Smooth muscle cells: 352.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 520.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.4" "HPA019142, HPA029401" Enhanced Approved Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA 250000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Cytosol "HPA019142: AB_1847093, HPA029401: AB_10601361" "unprognostic (3.45e-1)" "unprognostic (4.09e-2)" "unprognostic (8.71e-2)" "unprognostic (1.72e-1)" "unprognostic (5.79e-3)" "unprognostic (2.12e-1)" "unprognostic (6.27e-2)" "unprognostic (1.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.69e-2)" "unprognostic (6.06e-3)" "unprognostic (3.86e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (3.53e-3)" "prognostic unfavorable (4.54e-4)" COL6A2 ENSG00000142173 "Collagen type VI alpha 2 chain" P12110 21 46098112-46132848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 434.0;Fibroblasts: 1212.4;Leydig cells: 568.0;Mesothelial cells: 297.8;Ovarian stromal cells: 348.4;Peritubular cells: 434.9;Smooth muscle cells: 603.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 4.5;MAIT T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 4.5" "Cancer enhanced" "Detected in many" "Brain cancer: 574.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 64.8" "HPA007029, HPA030920, HPA038799" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Cell adhesion" NA NA 8200000 "Cluster 1: T-cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA007029: AB_1078549, HPA030920: AB_2673659, HPA038799: AB_2676214" "unprognostic (3.53e-1)" "unprognostic (3.76e-2)" "unprognostic (3.20e-2)" "unprognostic (4.87e-2)" "unprognostic (2.92e-2)" "unprognostic (1.38e-1)" "unprognostic (2.39e-1)" "unprognostic (5.28e-3)" "unprognostic (2.11e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.72e-14)" "unprognostic (2.13e-2)" "unprognostic (7.61e-2)" "unprognostic (2.31e-2)" "unprognostic (2.22e-3)" COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414328 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 403.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 210.6;Endometrial stromal cells: 326.2;Fibroblasts: 705.7;Leydig cells: 300.1;Ovarian stromal cells: 144.8;Smooth muscle cells: 173.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 441.4;Sarcoma: 220.8" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skin - Fibroblast_2" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 18.1" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "Cell adhesion" NA NA 1000000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" COL6A5 "COL29A1, FLJ35880, VWA4" ENSG00000172752 "Collagen type VI alpha 5 chain" 3 130345516-130484846 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lung: 5.5;skin 1: 4.7" "Cell type enhanced" "Detected in some" "Early spermatids: 6.0;Erythroid cells: 3.4;Fibroblasts: 4.4;Langerhans cells: 2.2;Late spermatids: 2.9;Oocytes: 2.2;Plasma cells: 1.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "midbrain: 3.3;thalamus: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "lymphoma: 4.3" "Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA043138 Uncertain "Secreted in other tissues" NA NA "Cluster 13: Skin - Cornification" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 49: Non-specific - Transcription" "HPA043138: AB_10796687" "unprognostic (3.45e-2)" "unprognostic (4.08e-2)" "unprognostic (6.01e-3)" "unprognostic (2.32e-1)" "unprognostic (3.42e-2)" "unprognostic (1.46e-6)" "unprognostic (8.44e-2)" "unprognostic (2.07e-3)" "unprognostic (2.47e-1)" "unprognostic (1.71e-1)" "unprognostic (7.58e-8)" "unprognostic (3.85e-2)" "unprognostic (4.51e-1)" "unprognostic (1.54e-1)" "unprognostic (2.79e-2)" COL6A6 ENSG00000206384 "Collagen type VI alpha 6 chain" A6NMZ7 3 130517177-130677044 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "parathyroid gland: 101.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.4;Fibroblasts: 15.6;Inhibitory neurons: 5.1;Oligodendrocyte precursor cells: 2.8;Oligodendrocytes: 4.2;Oocytes: 2.9;Rod photoreceptor cells: 3.1" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 3.5;testis cancer: 1.2" "Skin - Fibroblast_1" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "spinal cord: 13.2" HPA045239 Uncertain "Secreted to extracellular matrix" "Cell adhesion" NA NA 700000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 53: Fibroblasts - ECM organization" "HPA045239: AB_2679268" "unprognostic (4.86e-3)" "unprognostic (2.16e-2)" "unprognostic (9.91e-2)" "unprognostic (2.08e-4)" "unprognostic (2.79e-1)" "unprognostic (1.11e-5)" "unprognostic (3.74e-3)" "unprognostic (5.59e-2)" "unprognostic (1.42e-1)" "unprognostic (3.50e-2)" "unprognostic (8.90e-2)" "unprognostic (2.70e-1)" "unprognostic (2.96e-4)" "unprognostic (5.82e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-2)" "unprognostic (1.07e-1)" COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 95.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 64.2;Basal respiratory cells: 58.3;Basal squamous epithelial cells: 43.9;Endometrial stromal cells: 38.4" "Cancer enhanced" "Detected in all" "head and neck cancer: 41.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Endothelial cells" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "Cell adhesion" NA NA 6000 "Cluster 13: Skin - Cornification" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "Endoplasmic reticulum" Vesicles "CAB016357: AB_2229746, HPA018877: , HPA042420: AB_2677990" "unprognostic (2.69e-2)" "unprognostic (4.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-1)" "unprognostic (4.93e-2)" "prognostic favorable (6.31e-4)" "unprognostic (7.56e-2)" "unprognostic (1.25e-2)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.74e-2)" "unprognostic (0.00e+0)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-2)" COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 263.4;Mesothelial cells: 255.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 91.3;Kidney cancer: 98.2;thyroid cancer: 96.2" "Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 51 Vesicles "HPA053107: AB_2682046" "unprognostic (3.13e-2)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (3.71e-1)" "prognostic unfavorable (9.39e-8)" "unprognostic (2.98e-3)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-3)" COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 11.6;Fibroblasts: 9.2;Hofbauer cells: 6.2;Macrophages: 7.3;Microglial cells: 8.1;Peritubular cells: 6.0;Smooth muscle cells: 7.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 4.5" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 4.1" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Golgi apparatus" "HPA049788: AB_2680882" "unprognostic (9.98e-2)" "unprognostic (3.26e-2)" "unprognostic (2.51e-2)" "unprognostic (8.41e-3)" "unprognostic (8.76e-2)" "prognostic favorable (9.44e-4)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (3.50e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.08e-2)" "unprognostic (6.77e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-3)" COL9A1 ENSG00000112280 "Collagen type IX alpha 1 chain" P20849 6 70216040-70303084 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Deafness, Disease variant, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.0;choroid plexus: 24.6;prostate: 14.8" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 291.0" "Cancer enhanced" "Detected in many" "endometrial cancer: 3.6" "Region enriched" "Detected in all" 16 "choroid plexus: 91.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Rhabdoid: 2.8;Sarcoma: 2.1;skin cancer: 1.1" "Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA074749 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 120000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "HPA074749: AB_2732266" "unprognostic (2.18e-2)" "unprognostic (2.16e-1)" "unprognostic (2.25e-2)" "unprognostic (3.48e-3)" "unprognostic (5.72e-2)" "unprognostic (5.32e-4)" "unprognostic (3.24e-3)" "unprognostic (8.79e-2)" "unprognostic (1.25e-1)" "unprognostic (8.68e-2)" "unprognostic (8.27e-2)" "unprognostic (2.52e-1)" "unprognostic (5.69e-2)" "unprognostic (1.54e-1)" "unprognostic (2.09e-1)" "unprognostic (2.78e-1)" "unprognostic (3.62e-2)" COL9A2 "EDM2, MED" ENSG00000049089 "Collagen type IX alpha 2 chain" Q14055 1 40300489-40317813 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 127.9;pituitary gland: 105.2" "Cell type enhanced" "Detected in many" "Muller glia cells: 256.2;Oligodendrocyte precursor cells: 58.5;Oligodendrocytes: 119.2" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 3.2;myeloid DC: 1.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.2;granulocytes: 3.2" "Low cancer specificity" "Detected in many" "Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "HPA056316, HPA075286" Supported Approved Vesicles "Secreted to extracellular matrix" "No annotated function" NA NA 510000 "Cluster 22: Eosinophils - Transcription" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 11: Neuronal - Sensory perception" "Cluster 10: Muller glia cells - Visual perception" 2 Vesicles "HPA056316: AB_2683099, HPA075286: AB_2732288" "unprognostic (1.42e-2)" "unprognostic (3.54e-2)" "unprognostic (8.94e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.46e-2)" "unprognostic (1.83e-3)" "unprognostic (2.06e-2)" "unprognostic (9.00e-3)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (2.26e-1)" "unprognostic (1.16e-3)" "unprognostic (4.28e-2)" "unprognostic (2.56e-1)" "unprognostic (5.89e-2)" "unprognostic (1.71e-2)" COL9A3 "DJ885L7.4.1, EDM3, FLJ90759, IDD, MED" ENSG00000092758 "Collagen type IX alpha 3 chain" Q14050 20 62816244-62841159 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.3" "Cell type enriched" "Detected in many" 4 "Late spermatids: 419.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 30.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 154.3" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Liver - Hepatocytes, Skin - Outer root sheath cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA040125, HPA058323" Supported Approved "Nucleoplasm,Intermediate filaments" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 1 Nucleoplasm "Intermediate filaments" "HPA040125: AB_10805604, HPA058323: AB_2683679" "unprognostic (1.14e-3)" "unprognostic (2.14e-2)" "unprognostic (3.93e-1)" "unprognostic (1.21e-3)" "unprognostic (4.25e-2)" "unprognostic (2.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.24e-2)" "unprognostic (1.27e-1)" "unprognostic (1.25e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.67e-1)" COLEC10 "CL-10, CL-L1" ENSG00000184374 "Collectin subfamily member 10" Q9Y6Z7 8 118995452-119108455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 63.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.7;Excitatory neurons: 6.7;Inhibitory neurons: 5.2;Oligodendrocytes: 4.5;Oocytes: 23.5" "Cancer enhanced" "Detected in some" "liver cancer: 1.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 7.8;Neuroblastoma: 8.8" "Liver - Hepatic stellate cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" "No annotated function" NA NA 30000000 "Cluster 83: Liver - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (3.79e-4)" "unprognostic (6.25e-3)" "unprognostic (1.80e-3)" "unprognostic (7.73e-2)" "prognostic favorable (5.79e-4)" "unprognostic (1.05e-1)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.25e-2)" "unprognostic (9.02e-5)" "unprognostic (2.47e-1)" "unprognostic (1.82e-1)" "unprognostic (5.85e-5)" "unprognostic (7.12e-2)" COLEC11 "CL-11, CL-K1, MGC3279" ENSG00000118004 "Collectin subfamily member 11" Q9BWP8 2 3594832-3644644 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 139.6" "Cell type enhanced" "Detected in some" "Ovarian stromal cells: 155.5;Peritubular cells: 54.6;Proximal tubular cells: 89.3;Sertoli cells: 32.6" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 27.6" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA035241 Uncertain "Secreted to blood" "Developmental protein" NA NA 130000000 "Cluster 83: Liver - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 6: Ovarian stromal cells - Transcription" 2 "HPA035241: AB_10600701" "unprognostic (3.35e-1)" "unprognostic (4.73e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" "unprognostic (1.53e-2)" "unprognostic (1.40e-2)" "unprognostic (7.95e-3)" "unprognostic (5.85e-3)" "unprognostic (6.96e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.96e-2)" "unprognostic (2.26e-1)" "unprognostic (9.27e-3)" "unprognostic (7.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.60e-1)" COLGALT1 "FLJ22329, GLT25D1" ENSG00000130309 "Collagen beta(1-O)galactosyltransferase 1" Q8NBJ5 19 17555649-17583162 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 80.8;Hofbauer cells: 89.0;Kupffer cells: 67.2;Macrophages: 65.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 23.3;eosinophil: 11.2;intermediate monocyte: 26.6;myeloid DC: 17.1;non-classical monocyte: 19.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047821 Approved Approved Vesicles "Intracellular and membrane" Enzyme No No 9700 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 23: Non-specific - Transcription" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles "HPA047821: AB_2680168" "unprognostic (2.46e-1)" "unprognostic (1.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.65e-5)" "unprognostic (2.92e-3)" "unprognostic (2.92e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.43e-2)" "unprognostic (1.09e-1)" "unprognostic (8.87e-2)" "prognostic unfavorable (3.83e-4)" COLGALT2 "C1orf17, GLT25D2, KIAA0584" ENSG00000198756 "Collagen beta(1-O)galactosyltransferase 2" Q8IYK4 1 183929854-184037729 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.1" "Cell type enhanced" "Detected in many" "Astrocytes: 50.8;Excitatory neurons: 77.3;Inhibitory neurons: 68.5;Late spermatids: 81.2;Oligodendrocyte precursor cells: 108.0;Oligodendrocytes: 334.4" "Cancer enhanced" "Detected in many" "glioma: 11.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "basophil: 11.1" "Lineage enriched" "Detected in single" 30 "granulocytes: 11.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.5" "Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031749, HPA031750" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 2 Nucleoplasm Vesicles "HPA031749: AB_10599298, HPA031750: AB_10611252" "unprognostic (5.44e-3)" "unprognostic (3.08e-1)" "unprognostic (6.29e-5)" "unprognostic (2.08e-1)" "unprognostic (4.41e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (2.52e-1)" "unprognostic (2.00e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (5.13e-9)" "unprognostic (1.53e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (3.80e-2)" COLQ EAD ENSG00000206561 "Collagen like tail subunit of asymmetric acetylcholinesterase" Q9Y215 3 15450133-15521751 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Neurotransmitter degradation" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 17.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.6;Inhibitory neurons: 44.2;Late spermatids: 19.6;NK-cells: 36.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "MAIT T-cell: 61.0" "Lineage enriched" "Detected in many" 34 "T-cells: 61.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045876 Approved "Plasma membrane,Cell Junctions" "Secreted to blood" Other NA NA "Cluster 1: T-cells - Unknown function" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 17: Choroid plexus - Cilium" "Cluster 34: Testis cancer - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" 2 "Plasma membrane" "Cell Junctions" "HPA045876: AB_2679479" "unprognostic (4.08e-3)" "unprognostic (2.61e-2)" "unprognostic (2.13e-3)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (4.62e-2)" "unprognostic (1.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (1.28e-3)" "unprognostic (4.68e-1)" "unprognostic (7.00e-5)" "unprognostic (6.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-4)" COMP "EDM1, EPD1, MED, PSACH, THBS5" ENSG00000105664 "Cartilage oligomeric matrix protein" P49747 19 18782773-18791305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cell adhesion" Heparin-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 75.1;heart muscle: 63.2;skin 1: 78.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 15.9;Early spermatids: 35.1;Fibroblasts: 46.5;Glandular and luminal cells: 38.2;Late spermatids: 73.6;Smooth muscle cells: 31.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bladder cancer: 6.7;Gastric cancer: 4.2;ovarian cancer: 12.3;Rhabdoid: 5.1" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA077555 Approved "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA 1500000000 "Cluster 21: Testis - Unknown function" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 7 "Golgi apparatus" "HPA077555: " "unprognostic (1.26e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (9.08e-5)" "prognostic unfavorable (2.04e-4)" "unprognostic (8.05e-2)" "unprognostic (8.45e-2)" "unprognostic (3.62e-2)" "unprognostic (5.12e-2)" "unprognostic (1.65e-1)" "unprognostic (1.55e-2)" "unprognostic (2.18e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (1.52e-6)" "unprognostic (5.96e-3)" "unprognostic (1.44e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (6.95e-4)" COPA HEP-COP ENSG00000122218 "COPI coat complex subunit alpha" P53621 1 160288594-160343566 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028024 Supported Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" Hormone NA NA 150000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 65: Cerebellum - Nervous system development" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 28: Dendritic cells - Antigen presentation" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA028024: AB_10603787" "unprognostic (1.59e-2)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.77e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-2)" "unprognostic (5.41e-3)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.42e-2)" "unprognostic (3.14e-1)" "unprognostic (2.21e-1)" "unprognostic (5.03e-2)" "unprognostic (3.10e-1)" "unprognostic (2.05e-2)" "unprognostic (8.70e-2)" "unprognostic (2.03e-1)" "unprognostic (4.94e-2)" "unprognostic (1.39e-1)" COPS6 "CSN6, MOV34-34KD" ENSG00000168090 "COP9 signalosome subunit 6" Q7L5N1 7 100088969-100092187 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044315 Approved Supported Nucleoplasm "Intracellular and membrane" Other NA NA 110000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 15: Non-specific - Mixed function" 56 Nucleoplasm "HPA044315: AB_10959750" "unprognostic (1.48e-2)" "unprognostic (2.43e-2)" "unprognostic (6.56e-3)" "unprognostic (1.38e-1)" "unprognostic (5.84e-2)" "unprognostic (2.09e-2)" "unprognostic (3.62e-3)" "unprognostic (2.93e-2)" "unprognostic (2.00e-1)" "unprognostic (2.45e-2)" "unprognostic (4.96e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (6.72e-4)" "unprognostic (1.20e-1)" "unprognostic (3.58e-2)" "unprognostic (8.57e-2)" "unprognostic (8.77e-2)" CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "heart muscle: 55.0" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 70.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.1" "Heart muscle - Cardiomyocytes" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in many" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Enzyme Yes No "Cluster 30: Heart muscle - Heart development" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 4 "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: AB_2686324" "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" CORT "MGC32686, SST2" ENSG00000241563 Cortistatin O00230 1 10450031-10451998 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 52.7" "Cell type enhanced" "Detected in some" "Adipocytes: 1.8;Early spermatids: 5.2;Late spermatids: 5.3;Spermatocytes: 1.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in brain" Hormone NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 63: Late spermatids - Spermatogenesis" "unprognostic (1.25e-2)" "unprognostic (1.79e-2)" "unprognostic (1.65e-1)" "unprognostic (3.70e-3)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (1.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.94e-3)" "unprognostic (7.08e-7)" "unprognostic (2.01e-1)" "unprognostic (9.01e-4)" "unprognostic (1.62e-1)" "unprognostic (1.02e-1)" "unprognostic (3.02e-1)" "unprognostic (2.14e-4)" CP AB073614 ENSG00000047457 Ceruloplasmin P00450 3 149162410-149221829 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Copper transport, Ion transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 1815.4" "Cell type enhanced" "Detected in many" "Club cells: 294.5;Glandular and luminal cells: 433.6;Hepatocytes: 1419.3;Kupffer cells: 444.2;Muller glia cells: 594.4" "Cancer enhanced" "Detected in many" "liver cancer: 98.3" "Region enriched" "Detected in all" 5 "choroid plexus: 227.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 49.6;ovarian cancer: 45.2;Rhabdoid: 37.2" "Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001834, CAB008591" Supported "Secreted to blood" Transport NA NA 160000000000 440000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Hepatocytes - Metabolism" "CAB008591: AB_1613734, HPA001834: AB_1078502" "unprognostic (3.58e-1)" "unprognostic (4.24e-1)" "unprognostic (9.61e-2)" "unprognostic (1.80e-2)" "unprognostic (4.14e-2)" "unprognostic (1.02e-2)" "unprognostic (1.06e-1)" "unprognostic (2.97e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "unprognostic (6.03e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (1.14e-7)" "unprognostic (2.68e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (2.70e-1)" CPA1 CPA ENSG00000091704 "Carboxypeptidase A1" P15085 7 130380339-130388114 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5399 "pancreas: 230013.6" "Cell type enriched" "Detected in some" 16 "Exocrine glandular cells: 4867.4" "Cancer enriched" "Detected in some" 639 "pancreatic cancer: 1377.7" "Region enhanced" "Detected in single" "choroid plexus: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.1;Sarcoma: 1.2;Uterine cancer: 1.1" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA021836, CAB025197, HPA052215" Enhanced "Secreted to digestive system" Enzyme NA NA 110000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "CAB025197: , HPA021836: AB_1846005, HPA052215: AB_2681764" "unprognostic (8.41e-2)" "unprognostic (9.24e-4)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (3.97e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-6)" "unprognostic (4.99e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (4.37e-2)" CPA2 ENSG00000158516 "Carboxypeptidase A2" P48052 7 130266863-130289798 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 414 "pancreas: 43929.6" "Cell type enriched" "Detected in some" 12 "Exocrine glandular cells: 2649.0" "Cancer enriched" "Detected in many" 60 "pancreatic cancer: 411.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 2.2" "Pancreas - Exocrine glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA020342, HPA021317" Enhanced Approved "Golgi apparatus" "Secreted to digestive system" Enzyme NA NA 1500000 "Cluster 15: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 66: Non-specific - Mitochondria" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "Golgi apparatus" "HPA020342: AB_1846007, HPA021317: AB_1846008" "unprognostic (1.12e-1)" "unprognostic (3.97e-1)" "unprognostic (4.21e-2)" "unprognostic (1.82e-2)" "unprognostic (1.38e-1)" "unprognostic (6.76e-2)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.66e-1)" "unprognostic (3.84e-5)" "unprognostic (7.52e-2)" "unprognostic (1.42e-1)" "unprognostic (7.12e-2)" "unprognostic (8.48e-2)" CPA3 ENSG00000163751 "Carboxypeptidase A3" P15088 3 148865296-148897203 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 108.3;lung: 83.7" "Cell type enriched" "Detected in some" 180 "granulocytes: 4512.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 1540 "basophil: 1120.0" "Lineage enriched" "Detected in single" 5543 "granulocytes: 1120.0" "Cancer enriched" "Detected in some" 12 "Leukemia: 15.3" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Breast - Fibroblasts, Colon - Mast cells, Lung - Mast cells, Skeletal muscle - Macrophages" "Not detected" "Not detected" "HPA006479, HPA008689, CAB020712" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 47: Leukemia - Hemostasis" "Cluster 30: Granulocytes - Unknown function" "Golgi apparatus" Nucleoplasm "CAB020712: , HPA006479: AB_1078396, HPA008689: AB_1846009" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.66e-3)" "unprognostic (9.13e-3)" "unprognostic (3.50e-1)" "unprognostic (1.18e-3)" "unprognostic (2.47e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (9.51e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (3.50e-3)" "unprognostic (5.18e-3)" "unprognostic (3.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.69e-3)" CPA4 CPA3 ENSG00000128510 "Carboxypeptidase A4" Q9UI42 7 130293134-130324180 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.0;skin 1: 55.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 11.9;Basal respiratory cells: 23.5;Exocrine glandular cells: 48.8;Mesothelial cells: 9.1;Squamous epithelial cells: 11.5;Suprabasal keratinocytes: 19.9" "Cancer enhanced" "Detected in many" "cervical cancer: 10.0;head and neck cancer: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 157.9" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA021030 Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted in other tissues" Enzyme NA Yes 390000 "Cluster 13: Skin - Cornification" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "HPA021030: AB_1846010" "unprognostic (7.60e-3)" "unprognostic (4.00e-2)" "unprognostic (1.59e-3)" "unprognostic (3.63e-3)" "unprognostic (2.24e-2)" "unprognostic (2.91e-2)" "unprognostic (2.78e-2)" "unprognostic (4.36e-3)" "unprognostic (3.23e-1)" "unprognostic (5.79e-2)" "unprognostic (2.37e-3)" "unprognostic (6.49e-2)" "unprognostic (6.21e-10)" "unprognostic (2.39e-1)" "unprognostic (1.67e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (1.31e-4)" CPA5 ENSG00000158525 "Carboxypeptidase A5" Q8WXQ8 7 130344816-130368730 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 32.7" "Group enriched" "Detected in some" 25 "Early spermatids: 85.5;Late spermatids: 140.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 16.9;naive CD8 T-cell: 42.6;T-reg: 56.6" "Lineage enriched" "Detected in single" 101 "T-cells: 56.6" "Cancer enriched" "Detected in some" 26 "Sarcoma: 27.2" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA020322 Approved Nucleoplasm "Secreted in male reproductive system" Enzyme NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 44: Testis - Spermatogenesis" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Late spermatids - Unknown function" Nucleoplasm "HPA020322: AB_10960562" "unprognostic (2.44e-1)" "unprognostic (3.76e-1)" "unprognostic (1.50e-1)" "unprognostic (5.94e-2)" "unprognostic (4.96e-2)" "unprognostic (7.10e-3)" "unprognostic (1.64e-2)" "unprognostic (1.41e-2)" "unprognostic (3.26e-1)" "unprognostic (5.02e-2)" "unprognostic (5.83e-4)" "unprognostic (1.43e-1)" "unprognostic (8.88e-13)" "unprognostic (5.16e-2)" "unprognostic (1.32e-1)" "unprognostic (8.81e-2)" "unprognostic (3.08e-2)" CPA6 CPAH ENSG00000165078 "Carboxypeptidase A6" Q8N4T0 8 67422038-67746378 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.3;prostate: 2.7;retina: 2.2" "Cell type enhanced" "Detected in some" "Early spermatids: 27.3;Microglial cells: 11.6;Muller glia cells: 19.9;Oocytes: 14.0;Paneth cells: 16.9;Undifferentiated cells: 10.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.5;liver cancer: 1.9" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in some" 9 "olfactory bulb: 12.6" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 16: Intestinal goblet cells - Mucin production" "unprognostic (2.85e-2)" "unprognostic (1.95e-1)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (2.58e-1)" "unprognostic (2.24e-1)" "unprognostic (2.08e-1)" "unprognostic (2.88e-1)" "unprognostic (9.35e-2)" "unprognostic (1.65e-1)" "unprognostic (5.23e-2)" "unprognostic (6.99e-2)" "unprognostic (3.57e-4)" "unprognostic (9.61e-5)" "unprognostic (1.75e-1)" "unprognostic (9.09e-2)" "unprognostic (1.41e-2)" CPAMD8 "K-CAP, KIAA1283, VIP" ENSG00000160111 "C3 and PZP like alpha-2-macroglobulin domain containing 8" Q8IZJ3 19 16892951-17026815 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 35.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 47.1;Leydig cells: 30.0;Prostatic glandular cells: 49.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 6.2" "Region enriched" "Detected in single" 7 "spinal cord: 5.5" "HPA031327, HPA031328, HPA031329, HPA031330" Uncertain Uncertain "Focal adhesion sites" "Secreted to blood" "Enzyme inhibitor" NA NA 2700000 "Cluster 53: Non-specific - Glycosylation" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Basal prostatic cells - Lipid metabolism" "Focal adhesion sites" "HPA031327: AB_2673829, HPA031328: AB_2673830, HPA031329: , HPA031330: AB_10603788" "unprognostic (4.71e-3)" "unprognostic (1.07e-2)" "unprognostic (4.20e-2)" "unprognostic (2.76e-2)" "unprognostic (4.32e-2)" "unprognostic (4.06e-3)" "unprognostic (7.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-2)" "unprognostic (1.62e-1)" "unprognostic (4.24e-2)" "unprognostic (8.69e-2)" "unprognostic (1.01e-3)" "unprognostic (2.08e-1)" "unprognostic (8.45e-2)" "unprognostic (1.80e-2)" CPB1 ENSG00000153002 "Carboxypeptidase B1" P15086 3 148791102-148860187 "Enzymes, Plasma proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2733 "pancreas: 219818.0" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 3695.2" "Group enriched" "Detected in some" 312 "breast cancer: 293.8;pancreatic cancer: 641.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 4.0" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 15 "Rhabdoid: 14.4" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026158, HPA038069, HPA046340" Enhanced "Secreted to digestive system" Enzyme NA NA 88000000 "Cluster 20: Non-specific - DNA binding" "Cluster 15: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 1 "CAB026158: , HPA038069: AB_2675816, HPA046340: AB_2679628" "unprognostic (6.90e-2)" "unprognostic (3.79e-2)" "unprognostic (3.34e-2)" "unprognostic (2.64e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (6.26e-4)" "unprognostic (1.90e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (7.59e-2)" "unprognostic (4.51e-2)" "unprognostic (5.50e-8)" "unprognostic (3.08e-1)" "unprognostic (1.60e-1)" "unprognostic (4.93e-2)" CPB2 "CPU, PCPB, TAFI" ENSG00000080618 "Carboxypeptidase B2" Q96IY4 13 46053186-46105033 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 84 "liver: 1439.0" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 1226.7" "Cancer enriched" "Detected in some" 112 "liver cancer: 268.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "liver cancer: 11.2" "Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA004146 Approved "Secreted to blood" "Blood coagulation" NA NA 8500000000 "Cluster 31: Liver - Plasma proteins" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "HPA004146: AB_1078397" "unprognostic (3.44e-2)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (1.89e-2)" "unprognostic (7.69e-2)" "unprognostic (1.17e-2)" "prognostic favorable (2.06e-4)" "unprognostic (1.89e-1)" "unprognostic (2.74e-1)" "unprognostic (2.48e-1)" "unprognostic (3.17e-2)" "unprognostic (4.83e-2)" "unprognostic (3.20e-3)" "unprognostic (1.34e-1)" "unprognostic (7.10e-2)" "unprognostic (3.34e-2)" "unprognostic (9.61e-2)" CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Hypogonadotropic hypogonadism, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1074.3;retina: 718.7" "Cell type enhanced" "Detected in many" "Astrocytes: 689.9;Bipolar cells: 607.5;Cone photoreceptor cells: 1265.9;Leydig cells: 488.4;Muller glia cells: 513.4;Peritubular cells: 605.0;Prostatic glandular cells: 909.1;Rod photoreceptor cells: 732.8;Sertoli cells: 505.9" "Cancer enhanced" "Detected in all" "glioma: 240.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 315.7;thyroid cancer: 400.8" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907, CAB080183" Supported Approved Vesicles,Centrosome "Intracellular and membrane" Enzyme NA NA 600000 "Cluster 17: Neuronal - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" "Vesicles, Centrosome" "CAB024907: , CAB080183: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" CPN1 ENSG00000120054 "Carboxypeptidase N subunit 1" P15169 10 100042193-100081869 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "liver: 79.5" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 35.4" "Group enriched" "Detected in some" 12 "liver cancer: 26.6;melanoma: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "skin cancer: 35.3" "Liver - Hepatocytes" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Secreted to blood" Enzyme NA NA 13000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Hepatocytes - Metabolism" 4 "unprognostic (2.97e-2)" "unprognostic (2.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (6.75e-2)" "unprognostic (2.93e-2)" "unprognostic (5.26e-2)" "unprognostic (2.63e-1)" CPN2 ACBP ENSG00000178772 "Carboxypeptidase N subunit 2" P22792 3 194339768-194351328 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 212.0" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 143.8" "Cancer enriched" "Detected in some" 32 "liver cancer: 72.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "liver cancer: 7.5" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA004732 Uncertain "Secreted to blood" "No annotated function" NA NA 25000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "HPA004732: AB_1078561" "unprognostic (4.27e-2)" "unprognostic (3.04e-1)" "unprognostic (1.42e-1)" "unprognostic (4.12e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.27e-1)" "unprognostic (8.65e-2)" "unprognostic (8.56e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.91e-2)" "unprognostic (2.40e-1)" "unprognostic (6.90e-5)" "unprognostic (8.42e-2)" CPO ENSG00000144410 "Carboxypeptidase O" Q8IVL8 2 206939518-206969474 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 108.7" "Cell type enriched" "Detected in some" 8 "Proximal enterocytes: 344.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 29 "basophil: 11.9" "Lineage enriched" "Detected in single" 83 "granulocytes: 11.9" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Intracellular and membrane" Enzyme NA NA "Cluster 25: Small intestine - Absorption" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (9.39e-2)" "unprognostic (2.64e-1)" "unprognostic (2.95e-2)" "unprognostic (5.21e-2)" "unprognostic (2.28e-1)" "unprognostic (1.27e-2)" "unprognostic (1.16e-1)" "unprognostic (9.06e-2)" "unprognostic (4.03e-1)" "unprognostic (1.33e-1)" "unprognostic (3.75e-3)" "unprognostic (1.22e-1)" "unprognostic (3.60e-2)" "unprognostic (2.52e-1)" "unprognostic (6.56e-2)" "unprognostic (4.03e-2)" "unprognostic (4.89e-2)" CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 219.3" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 278.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 251.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" Enzyme NA NA 51000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 51: Thyroid gland - Unknown function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 197.7;lymphoid tissue: 213.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 344.8;Kupffer cells: 267.2;Langerhans cells: 527.4;Macrophages: 250.9;Schwann cells: 1193.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1139.6;intermediate monocyte: 955.1;myeloid DC: 1321.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1321.5;monocytes: 1139.6" "Cancer enhanced" "Detected in many" "testis cancer: 89.4" "Adipose subcutaneous - Macrophages, Colon - Fibroblasts, Liver - Kupffer cells, Lung - Macrophages, Prostate - Fibroblasts, Skin - Langerhans cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 760000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Dendritic cells - Antigen presentation" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" CPXM1 "CPX-1, CPX1, CPXM" ENSG00000088882 "Carboxypeptidase X, M14 family member 1" Q96SM3 20 2794074-2800627 "Enzymes, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 109.7" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 143.0;Fibroblasts: 44.4;Mesothelial cells: 76.3;Ovarian stromal cells: 37.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Leukemia: 47.1;Neuroblastoma: 82.6" "Adipose visceral - Adipose progenitor cells, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 17.3" "Secreted in other tissues" Enzyme NA NA 490000 "Cluster 14: Non-specific - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" "unprognostic (7.48e-2)" "unprognostic (3.61e-1)" "unprognostic (6.70e-2)" "unprognostic (1.47e-2)" "unprognostic (3.41e-1)" "unprognostic (5.24e-2)" "unprognostic (1.82e-2)" "unprognostic (1.84e-2)" "unprognostic (2.98e-2)" "unprognostic (9.32e-2)" "unprognostic (7.02e-2)" "unprognostic (3.23e-2)" "prognostic unfavorable (4.62e-10)" "unprognostic (1.30e-1)" "unprognostic (1.49e-1)" "unprognostic (5.55e-3)" "unprognostic (1.27e-2)" CPXM2 "CPX2, UNQ676" ENSG00000121898 "Carboxypeptidase X, M14 family member 2" Q8N436 10 123706207-123940267 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 182.3" "Cell type enhanced" "Detected in many" "Adipocytes: 31.2;Early spermatids: 66.5;Endothelial cells: 31.0;Late spermatids: 192.7;Oligodendrocytes: 33.1;Peritubular cells: 74.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 171.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 15.2;testis cancer: 25.8" "Colon - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048375 Uncertain "Secreted - unknown location" "No annotated function" NA NA 62000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA048375: AB_2680377" "unprognostic (1.50e-1)" "unprognostic (3.66e-1)" "unprognostic (2.58e-2)" "unprognostic (4.02e-3)" "unprognostic (2.69e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.57e-2)" "unprognostic (4.42e-2)" "unprognostic (2.14e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (1.16e-3)" CPZ ENSG00000109625 "Carboxypeptidase Z" Q66K79 4 8592660-8619759 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 147.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 4.7;Granulosa cells: 4.0;Leydig cells: 2.4;Microglial cells: 2.7;Ovarian stromal cells: 6.1;Schwann cells: 4.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Liver - Hepatic stellate cells, Skin - Fibroblast_1, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA078608 Approved "Plasma membrane" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" "Plasma membrane" "HPA078608: " "unprognostic (2.58e-1)" "unprognostic (7.16e-2)" "unprognostic (4.83e-2)" "unprognostic (1.42e-1)" "unprognostic (7.77e-2)" "unprognostic (2.20e-2)" "unprognostic (2.98e-1)" "unprognostic (7.77e-2)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (7.23e-8)" "unprognostic (4.30e-3)" "unprognostic (3.58e-2)" "unprognostic (6.13e-4)" "unprognostic (5.51e-2)" CR1L ENSG00000197721 "Complement C3b/C4b receptor 1 like" Q2VPA4 1 207645113-207738416 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "bone marrow: 1.5" "Cell type enriched" "Detected in some" 8 "Erythroid cells: 82.6" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049348 Approved "Secreted in other tissues" "No annotated function" NA NA "Cluster 77: Bone marrow - Cell proliferation" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" "HPA049348: AB_2680723" "unprognostic (2.35e-2)" "unprognostic (8.27e-2)" "unprognostic (1.99e-1)" "unprognostic (8.89e-2)" "unprognostic (1.31e-2)" "unprognostic (5.50e-2)" "unprognostic (2.01e-1)" "unprognostic (7.45e-2)" "unprognostic (5.27e-2)" "unprognostic (8.21e-3)" "unprognostic (7.94e-2)" "unprognostic (3.02e-1)" "unprognostic (6.33e-2)" "unprognostic (2.02e-1)" "unprognostic (8.90e-2)" "unprognostic (1.31e-2)" "unprognostic (9.68e-2)" CRB1 "LCA8, RP12" ENSG00000134376 "Crumbs cell polarity complex component 1" P82279 1 197268204-197478455 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "retina: 72.4" "Cell type enhanced" "Detected in some" "Astrocytes: 445.3;Cone photoreceptor cells: 117.2;Inhibitory neurons: 124.5;Oligodendrocyte precursor cells: 262.7;Oligodendrocytes: 98.3;Rod photoreceptor cells: 149.5" "Cancer enriched" "Detected in single" 12 "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 7.8" "Lineage enriched" "Detected in single" 28 "granulocytes: 7.8" "Group enriched" "Detected in some" 5 "cervical cancer: 4.7;Sarcoma: 4.6" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA061250, HPA063127" Approved Uncertain Vesicles "Secreted in brain" "No annotated function" NA NA "Cluster 76: Retina - Visual perception" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Astrocytes - Unknown function" 4 Vesicles "HPA061250: AB_2684458, HPA063127: AB_2684944" "unprognostic (1.96e-1)" "unprognostic (5.38e-3)" "unprognostic (2.92e-3)" "unprognostic (1.50e-2)" "unprognostic (5.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.38e-1)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (1.48e-3)" "unprognostic (2.59e-1)" "unprognostic (2.01e-3)" "unprognostic (1.78e-3)" "unprognostic (1.56e-1)" "unprognostic (3.36e-2)" "unprognostic (2.96e-1)" CRB2 "FLJ16786, FLJ38464" ENSG00000148204 "Crumbs cell polarity complex component 2" Q5IJ48 9 123356170-123380324 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Gastrulation, Sensory transduction, Vision" "Developmental protein" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.3;kidney: 5.6;retina: 7.8" "Cell type enhanced" "Detected in many" "Astrocytes: 38.4;Bipolar cells: 36.8;Cone photoreceptor cells: 62.9;Mesothelial cells: 27.4;Oligodendrocytes: 25.0;Rod photoreceptor cells: 106.8" "Group enriched" "Detected in some" 7 "glioma: 9.4;ovarian cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.8" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043674 Approved Supported "Intracellular and membrane" "Developmental protein" NA NA 210000 "Cluster 17: Neuronal - Synaptic function" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 66: Photoreceptor cells - Visual perception" "HPA043674: AB_10962974" "unprognostic (1.38e-2)" "unprognostic (2.39e-2)" "unprognostic (1.26e-1)" "unprognostic (2.83e-4)" "unprognostic (2.85e-2)" "unprognostic (1.14e-2)" "unprognostic (2.31e-1)" "unprognostic (3.69e-4)" "unprognostic (1.20e-1)" "unprognostic (7.28e-3)" "unprognostic (4.66e-3)" "unprognostic (3.09e-1)" "unprognostic (5.56e-5)" "unprognostic (1.31e-1)" "unprognostic (1.55e-1)" "unprognostic (4.38e-2)" "unprognostic (3.38e-1)" CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 494.0;Kupffer cells: 559.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.9;classical monocyte: 128.5;eosinophil: 75.9;intermediate monocyte: 75.6;myeloid DC: 89.9;neutrophil: 43.8;non-classical monocyte: 72.7" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.9;monocytes: 128.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" Other NA NA 520000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Liver - Plasma proteins" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" CREG2 ENSG00000175874 "Cellular repressor of E1A stimulated genes 2" Q8IUH2 2 101345550-101387503 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 67 "brain: 55.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 63.9;Granulosa cells: 11.5;Inhibitory neurons: 26.4;Oligodendrocytes: 11.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.3" "Colon - Colon enteroendocrine cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038224 Enhanced "Secreted in brain" "No annotated function" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" "HPA038224: AB_10673167" "unprognostic (5.09e-2)" "unprognostic (3.78e-3)" "unprognostic (4.10e-3)" "unprognostic (8.15e-3)" "unprognostic (5.63e-3)" "unprognostic (9.68e-3)" "unprognostic (4.52e-8)" "unprognostic (3.86e-4)" "unprognostic (1.39e-1)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (7.69e-2)" "unprognostic (5.41e-3)" "unprognostic (4.44e-2)" "unprognostic (2.91e-1)" "unprognostic (8.26e-3)" "unprognostic (7.77e-2)" CRELD1 "AVSD2, CIRRIN" ENSG00000163703 "Cysteine rich with EGF like domains 1" Q96HD1 3 9933793-9945413 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.2;Excitatory neurons: 36.8;Inhibitory neurons: 35.5;Oligodendrocytes: 20.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026964 Uncertain Approved Nucleoli,Cytosol "Intracellular and membrane" Enzyme NA NA 19000000 "Cluster 25: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 49: Non-specific - Transcription" Cytosol Nucleoli "HPA026964: AB_10602210" "unprognostic (3.06e-2)" "unprognostic (1.08e-1)" "unprognostic (2.69e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.07e-4)" "unprognostic (3.03e-1)" "unprognostic (3.59e-1)" "unprognostic (2.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.19e-1)" "unprognostic (1.92e-2)" "unprognostic (4.59e-2)" "unprognostic (1.14e-2)" "unprognostic (6.31e-2)" "unprognostic (9.51e-2)" "unprognostic (2.89e-1)" "unprognostic (3.78e-2)" CRELD2 MGC11256 ENSG00000184164 "Cysteine rich with EGF like domains 2" Q6UXH1 22 49918167-49927540 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 400.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000603, CAB025604" Approved "Intracellular and membrane" Enzyme NA NA 480000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 46: Brainstem - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 77: Plasma cells - Protein processing" 1 "CAB025604: , HPA000603: AB_1078565" "unprognostic (1.12e-1)" "unprognostic (7.35e-2)" "unprognostic (1.10e-1)" "prognostic favorable (2.42e-7)" "unprognostic (5.04e-2)" "unprognostic (5.43e-2)" "unprognostic (3.21e-3)" "unprognostic (2.71e-1)" "unprognostic (3.60e-1)" "unprognostic (1.24e-1)" "unprognostic (2.57e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (1.34e-9)" "unprognostic (6.13e-2)" "unprognostic (3.01e-1)" "unprognostic (7.30e-2)" "unprognostic (4.02e-1)" CRH "CRF, CRH1" ENSG00000147571 "Corticotropin releasing hormone" P06850 8 66176376-66178464 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 46.0" "Cell type enriched" "Detected in some" 6 "Syncytiotrophoblasts: 189.6" "Cancer enriched" "Detected in some" 28 "urothelial cancer: 34.5" "Region enriched" "Detected in many" 6 "medulla oblongata: 317.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "Rhabdoid: 960.6" "Pancreas - Alpha cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" Hormone NA NA 10000 "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 11 "unprognostic (1.62e-1)" "unprognostic (9.68e-2)" "unprognostic (1.00e-1)" "unprognostic (9.55e-2)" "unprognostic (7.22e-3)" CRHBP "CRF-BP, CRFBP" ENSG00000145708 "Corticotropin releasing hormone binding protein" P24387 5 76953045-76981158 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.2;liver: 161.5" "Cell type enhanced" "Detected in some" "Adipocytes: 102.7;Endothelial cells: 73.6;Fibroblasts: 197.0;Inhibitory neurons: 31.0;Kupffer cells: 69.5" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Brain cancer: 12.3" "Kidney - Podocytes, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036234, HPA046120" Approved Supported "Secreted to blood" "No annotated function" NA NA 69000000 "Cluster 83: Liver - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA036234: , HPA046120: AB_10959760" "unprognostic (1.41e-1)" "unprognostic (2.00e-2)" "unprognostic (1.14e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.36e-3)" "unprognostic (4.44e-5)" "unprognostic (2.16e-1)" "unprognostic (7.08e-2)" "unprognostic (4.98e-4)" "unprognostic (1.09e-1)" "unprognostic (6.63e-5)" "unprognostic (2.76e-2)" "unprognostic (4.64e-1)" "unprognostic (1.74e-1)" "unprognostic (2.95e-2)" CRHR2 "CRF-RB, CRF2, HM-CRF" ENSG00000106113 "Corticotropin releasing hormone receptor 2" Q13324 7 30651942-30700129 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 21.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 8.0;Horizontal cells: 11.3;Inhibitory neurons: 4.7" "Not detected" "Not detected" "Region enhanced" "Detected in all" "choroid plexus: 48.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 5.5" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Low region specificity" "Detected in many" HPA073345 Supported "Plasma membrane" "Secreted - unknown location" Receptor NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA073345: " "unprognostic (7.14e-2)" "unprognostic (4.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.24e-3)" "unprognostic (5.69e-2)" "unprognostic (8.58e-2)" "unprognostic (6.00e-2)" "unprognostic (1.86e-4)" "unprognostic (2.01e-1)" "unprognostic (3.07e-1)" "unprognostic (5.90e-4)" "unprognostic (4.02e-2)" "unprognostic (8.29e-4)" "unprognostic (3.73e-3)" "unprognostic (2.84e-3)" "unprognostic (1.81e-1)" "unprognostic (3.84e-1)" CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355778-36551135 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 158.3" "Cell type enhanced" "Detected in many" "Adipocytes: 241.5;Smooth muscle cells: 170.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" "No annotated function" NA NA 170000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA000556: AB_1078567" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (6.39e-2)" "unprognostic (3.17e-3)" "unprognostic (3.88e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (4.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.51e-4)" "unprognostic (1.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.67e-2)" CRISP1 "AEGL1, ARP, CRISP-1, HSCRISP1D, HSCRISP1G, HUMARP" ENSG00000124812 "Cysteine rich secretory protein 1" P54107 6 49834257-49877096 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "epididymis: 1536.4" "Group enriched" "Detected in some" 48 "Early spermatids: 51.7;Late spermatids: 75.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028445, HPA030534" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 35000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 34: Testis cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" "HPA028445: AB_10670428, HPA030534: AB_2732459" CRISP2 "CRISP-2, CT36, GAPDL5, TPX1" ENSG00000124490 "Cysteine rich secretory protein 2" P16562 6 49692358-49713590 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "testis: 490.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 22229.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.3" "Region enhanced" "Detected in single" "choroid plexus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031248 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 820000 "Cluster 20: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 36: Late spermatids - Unknown function" "HPA031248: AB_10602211" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (7.38e-2)" "unprognostic (2.35e-2)" "unprognostic (9.23e-3)" "unprognostic (4.05e-2)" CRISP3 "Aeg2, CRISP-3, CRS3, dJ442L6.3, SGP28" ENSG00000096006 "Cysteine rich secretory protein 3" P54108 6 49727376-49744437 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 1164.2;salivary gland: 2242.7" "Group enriched" "Detected in many" 7 "Glandular and luminal cells: 608.9;Mucus glandular cells: 895.5;Secretory cells: 1674.5" "Group enriched" "Detected in many" 7 "breast cancer: 31.9;pancreatic cancer: 59.8;prostate cancer: 85.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "neutrophil: 2.6;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 19 "granulocytes: 2.6;monocytes: 1.2" "Cancer enhanced" "Detected in many" "breast cancer: 108.0;prostate cancer: 44.2" "Lung - Neutrophil_1, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA054392 Supported "Secreted in other tissues" "No annotated function" NA NA 420000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA054392: AB_2682472" "unprognostic (1.28e-2)" "unprognostic (7.01e-2)" "unprognostic (8.93e-2)" "unprognostic (5.56e-2)" "unprognostic (1.02e-1)" "unprognostic (2.22e-4)" "unprognostic (5.30e-2)" "unprognostic (6.70e-2)" "unprognostic (9.16e-2)" "unprognostic (4.34e-3)" "unprognostic (1.91e-1)" "unprognostic (1.93e-1)" CRISPLD1 "Cocoacrisp, DKFZp762F133, LCRISP1" ENSG00000121005 "Cysteine rich secretory protein LCCL domain containing 1" Q9H336 8 74984505-75034558 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 28.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 36.4;Ciliated cells: 27.0;Oligodendrocyte precursor cells: 76.4;Oocytes: 28.7;Prostatic glandular cells: 48.6" "Cancer enhanced" "Detected in many" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 64.3" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024725 Uncertain "Secreted - unknown location" "No annotated function" NA NA 8200 "Cluster 51: Thyroid gland - Unknown function" "Cluster 39: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA024725: AB_1847238" "unprognostic (2.16e-1)" "unprognostic (5.88e-2)" "unprognostic (4.01e-2)" "unprognostic (3.78e-2)" "unprognostic (3.85e-2)" "unprognostic (1.65e-1)" "unprognostic (2.09e-4)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (5.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (7.39e-3)" "unprognostic (2.38e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" CRISPLD2 "DKFZP434B044, LCRISP2, LGL1" ENSG00000103196 "Cysteine rich secretory protein LCCL domain containing 2" Q9H0B8 16 84819985-84920768 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 127.7;Fibroblasts: 248.6;Leydig cells: 267.3;Peritubular cells: 251.3;Smooth muscle cells: 328.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 87.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 87.5" "Cancer enhanced" "Detected in many" "Kidney cancer: 28.9" "Colon - Neutrophils, Liver - Cholangiocyte" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 20.4" "HPA030055, HPA075372" Approved Approved Vesicles "Secreted to blood" "No annotated function" NA No 219000000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" Vesicles "HPA030055: AB_10611821, HPA075372: " "unprognostic (8.91e-3)" "unprognostic (3.05e-1)" "unprognostic (2.63e-2)" "unprognostic (2.02e-2)" "unprognostic (7.12e-2)" "unprognostic (2.30e-1)" "unprognostic (2.11e-2)" "unprognostic (5.58e-3)" "unprognostic (1.48e-1)" "unprognostic (5.50e-2)" "unprognostic (2.67e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (1.97e-6)" "unprognostic (7.35e-3)" "unprognostic (3.38e-2)" "unprognostic (2.99e-3)" "unprognostic (5.15e-3)" CRLF1 "CISS, CISS1, CLF, CLF-1" ENSG00000006016 "Cytokine receptor like factor 1" O75462 19 18572220-18607741 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.8;heart muscle: 85.7" "Cell type enhanced" "Detected in many" "Astrocytes: 14.6;Ciliated cells: 15.8;Fibroblasts: 48.8;Pancreatic endocrine cells: 27.2;Serous glandular cells: 21.4;Smooth muscle cells: 56.3" "Group enriched" "Detected in all" 4 "lung cancer: 27.4;thyroid cancer: 36.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 46.5;thyroid cancer: 46.5" "Region enriched" "Detected in many" 7 "hippocampal formation: 21.1" "Group enriched" "Detected in some" 6 "cerebellum: 2.7;spinal cord: 9.9" "HPA041493, HPA041793" Approved "Secreted in other tissues" Receptor NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 "HPA041493: AB_10795637, HPA041793: AB_10804117" "unprognostic (1.97e-1)" "unprognostic (2.29e-1)" "unprognostic (2.34e-3)" "unprognostic (9.31e-3)" "unprognostic (1.58e-2)" "unprognostic (1.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (4.95e-2)" "unprognostic (7.92e-2)" "prognostic unfavorable (3.96e-4)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-2)" "unprognostic (5.27e-3)" CRLF2 "CRL2, TSLPR" ENSG00000205755 "Cytokine receptor like factor 2" Q9HC73 X 1187549-1212723 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.8;gallbladder: 1.3;lymphoid tissue: 1.5" "Group enriched" "Detected in some" 5 "granulocytes: 31.5;Langerhans cells: 9.3" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.2" "Group enriched" "Detected in some" 4 "Adrenocortical cancer: 7.0;Leukemia: 7.4;lymphoma: 2.4;Myeloma: 5.2" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Lung - Mast cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA075272 Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 77: Bone marrow - Cell proliferation" "Cluster 6: Leukemia - Signal transduction" "Cluster 14: Langerhans cells - Innate immune response" "Plasma membrane" "HPA075272: " "unprognostic (7.84e-2)" "unprognostic (7.99e-4)" "unprognostic (6.02e-3)" "unprognostic (2.01e-2)" "unprognostic (1.15e-3)" "unprognostic (2.31e-6)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "unprognostic (4.59e-3)" "unprognostic (1.09e-1)" "unprognostic (1.46e-2)" "unprognostic (9.72e-3)" "unprognostic (6.88e-5)" "unprognostic (7.09e-3)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.62e-1)" CRP PTX1 ENSG00000132693 "C-reactive protein" P02741 1 159712289-159714589 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 80 "liver: 9151.6" "Group enriched" "Detected in some" 7 "Ductal cells: 1316.9;Hepatocytes: 3016.1" "Cancer enriched" "Detected in some" 13 "liver cancer: 1010.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gastric cancer: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005036, HPA027367, HPA027396" Supported Approved "Nucleoplasm,Vesicles,Intermediate filaments" "Secreted to blood" "Acute phase" NA NA 2920000000 5200000000 "Cluster 31: Liver - Plasma proteins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 62: Hepatocytes - Metabolism" 7 "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB005036: AB_562362, HPA027367: AB_1847216, HPA027396: AB_1847217" "unprognostic (3.74e-1)" "unprognostic (5.31e-2)" "unprognostic (2.97e-2)" "unprognostic (1.27e-1)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (4.17e-10)" "unprognostic (3.39e-2)" "unprognostic (3.48e-1)" "unprognostic (5.60e-2)" "unprognostic (6.61e-2)" CRTAC1 "ASPIC1, CEP-68, FLJ10320" ENSG00000095713 "Cartilage acidic protein 1" Q9NQ79 10 97865000-98030828 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 37.0;lung: 48.4;seminal vesicle: 32.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 125.1;Basal prostatic cells: 67.9;Inhibitory neurons: 61.2;Oligodendrocyte precursor cells: 51.4;Secretory cells: 94.3" "Cancer enhanced" "Detected in many" "melanoma: 43.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 6.0;skin cancer: 4.9" "Colon - Enteric glia cells, Liver - Vascular Endothelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008175 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 550000000 "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 72: Alveolar cells - Lung function" 4 "HPA008175: AB_1847254" "unprognostic (2.55e-1)" "unprognostic (6.41e-3)" "unprognostic (4.90e-3)" "prognostic unfavorable (5.01e-6)" "unprognostic (2.54e-1)" "unprognostic (6.96e-3)" "unprognostic (9.30e-2)" "unprognostic (9.13e-2)" "unprognostic (1.02e-2)" "unprognostic (3.01e-1)" "unprognostic (7.66e-2)" "unprognostic (1.69e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.70e-4)" "unprognostic (1.05e-2)" "unprognostic (3.29e-3)" "prognostic favorable (1.51e-4)" CRTAP "CASP, LEPREL3, P3H5" ENSG00000170275 "Cartilage associated protein" O75718 3 33114014-33147773 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 377.9" "Group enriched" "Detected in all" 5 "dendritic cells: 307.2;monocytes: 377.9" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043598, HPA044150" Approved Approved "Intermediate filaments,Actin filaments,Cytosol" "Secreted to blood" "No annotated function" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 62: Connective tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 49: Non-specific - Transcription" 1 "Intermediate filaments, Actin filaments, Cytosol" "HPA043598: AB_10960991, HPA044150: AB_10959594" "unprognostic (5.29e-2)" "unprognostic (2.64e-1)" "unprognostic (2.13e-1)" "unprognostic (1.85e-3)" "unprognostic (7.36e-2)" "unprognostic (4.73e-3)" "unprognostic (4.28e-2)" "unprognostic (1.87e-1)" "unprognostic (9.97e-2)" "unprognostic (4.62e-2)" "unprognostic (3.70e-1)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-1)" "unprognostic (9.93e-2)" "unprognostic (1.28e-3)" CRY2 ENSG00000121671 "Cryptochrome circadian regulator 2" Q49AN0 11 45847118-45883248 "Predicted intracellular proteins" "Biological rhythms, Sensory transduction, Transcription, Transcription regulation" "Photoreceptor protein, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bipolar cells: 111.9;Horizontal cells: 88.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037577 Supported Supported "Nuclear speckles,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Non-specific - Unknown function" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 29 "Nuclear speckles" Cytosol "HPA037577: AB_10672497" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (1.31e-2)" "unprognostic (9.16e-2)" "unprognostic (3.09e-2)" "prognostic favorable (6.82e-5)" "unprognostic (1.48e-3)" "unprognostic (1.67e-1)" "unprognostic (5.07e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.01e-1)" "prognostic favorable (6.44e-15)" "unprognostic (8.13e-3)" "unprognostic (1.89e-1)" "unprognostic (4.24e-2)" "unprognostic (2.24e-1)" CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 10335.0;skeletal muscle: 6727.5;tongue: 9029.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 7159.1;Proximal tubular cells: 7075.7;Schwann cells: 1861.7;Skeletal myocytes: 4337.4" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 236.2;ovarian cancer: 273.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA 370000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 18 "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" CSAD "CSD, PCAP" ENSG00000139631 "Cysteine sulfinic acid decarboxylase" Q9Y600 12 53157663-53180925 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 16.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039487, HPA079296" Approved Approved "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" 1 "Endoplasmic reticulum, Vesicles, Plasma membrane" "HPA039487: AB_10672776, HPA079296: " "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (1.57e-1)" "unprognostic (7.99e-2)" "prognostic favorable (6.33e-4)" "prognostic favorable (1.37e-4)" "unprognostic (2.46e-2)" "unprognostic (7.87e-3)" "unprognostic (1.01e-1)" "prognostic favorable (3.39e-4)" "unprognostic (3.48e-2)" "prognostic unfavorable (1.93e-6)" "unprognostic (4.59e-2)" "unprognostic (3.47e-1)" "unprognostic (1.38e-1)" "prognostic favorable (6.81e-6)" CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 59.0;granulocytes: 199.8;Secretory cells: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" Cytokine NA NA 270000 22000000 "Cluster 19: Eosinophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 53: Fibroblasts - ECM organization" 7 "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.4;placenta: 99.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 115.8;Hofbauer cells: 327.3;Kupffer cells: 256.3;Langerhans cells: 98.3;Macrophages: 218.3;Microglial cells: 128.8;monocytes: 218.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.5;non-classical monocyte: 650.1" "Lineage enriched" "Detected in many" 5 "monocytes: 650.1" "Cancer enhanced" "Detected in many" "Leukemia: 13.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA 1600000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 3 "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" CSF2 "GM-CSF, GMCSF" ENSG00000164400 "Colony stimulating factor 2" P04141 5 132073789-132076170 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lung: 2.0" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 16.3;Basal respiratory cells: 7.5;Ductal cells: 11.0;granulocytes: 13.5;NK-cells: 21.0;T-cells: 23.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "NK-cell: 6.3" "Lineage enriched" "Detected in single" 12 "NK-cells: 6.3" "Cancer enhanced" "Detected in many" "Bile duct cancer: 27.2;Kidney cancer: 31.4" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA057404, HPA062006" Enhanced Vesicles "Secreted to blood" Cytokine NA NA 23900 "Cluster 15: NK-cells - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 4 Vesicles "HPA057404: AB_2683428, HPA062006: AB_2684654" "unprognostic (7.29e-2)" "unprognostic (2.49e-3)" "unprognostic (8.77e-2)" "unprognostic (2.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (1.47e-2)" "unprognostic (2.64e-1)" "unprognostic (3.68e-3)" "unprognostic (1.87e-8)" "unprognostic (4.81e-2)" "unprognostic (1.22e-1)" "unprognostic (9.07e-2)" "unprognostic (2.06e-2)" CSF2RA "alphaGMR, CD116, CSF2R" ENSG00000198223 "Colony stimulating factor 2 receptor subunit alpha" P15509 X 1268800-1310381 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 243.7;Extravillous trophoblasts: 130.8;Langerhans cells: 703.6;Macrophages: 108.0;Schwann cells: 140.4;Syncytiotrophoblasts: 345.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 319.8" "Group enriched" "Detected in all" 29 "dendritic cells: 170.1;granulocytes: 319.8;monocytes: 160.9" "Cancer enriched" "Detected in many" 7 "Adrenocortical cancer: 111.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Pancreas - Macrophages, Skeletal muscle - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in single" CAB016148 Uncertain "Secreted to blood" Receptor NA NA 13000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" 1 "CAB016148: AB_626868" "unprognostic (4.19e-2)" "prognostic favorable (2.38e-5)" "unprognostic (5.47e-2)" "unprognostic (4.33e-2)" "unprognostic (4.88e-2)" "prognostic favorable (2.81e-4)" "unprognostic (8.24e-2)" "unprognostic (2.17e-1)" "unprognostic (5.55e-2)" "unprognostic (8.48e-2)" "unprognostic (8.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.89e-2)" "unprognostic (8.91e-3)" "prognostic unfavorable (5.53e-4)" "unprognostic (3.60e-1)" "unprognostic (9.44e-2)" CSF3 "C17orf33, G-CSF, GCSF, MGC45931" ENSG00000108342 "Colony stimulating factor 3" P09919 17 40015361-40017813 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 119.2;urinary bladder: 55.3" "Cell type enhanced" "Detected in many" "Adipocytes: 62.7;Alveolar cells type 2: 52.0;Basal respiratory cells: 187.5;Endothelial cells: 129.4;Ionocytes: 208.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 35.5;Sarcoma: 52.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Cytokine NA NA 6170 "Cluster 57: Lung - Lung function" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "unprognostic (3.59e-3)" "unprognostic (1.57e-2)" "unprognostic (1.73e-1)" "prognostic favorable (8.45e-4)" "unprognostic (1.06e-2)" "unprognostic (3.40e-2)" "unprognostic (1.10e-1)" "unprognostic (1.16e-2)" "unprognostic (1.74e-1)" "unprognostic (2.26e-1)" "unprognostic (2.82e-2)" "unprognostic (7.40e-4)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (4.10e-2)" "unprognostic (4.80e-3)" CSF3R "CD114, GCSFR" ENSG00000119535 "Colony stimulating factor 3 receptor" Q99062 1 36466043-36483278 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.3;lung: 132.6;lymphoid tissue: 366.7" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 395.7;Syncytiotrophoblasts: 1355.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 1924.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 1924.2" "Cancer enriched" "Detected in some" 25 "Leukemia: 32.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017116, HPA048086" Enhanced "Intracellular and membrane" Receptor NA NA 150000 "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 1 "CAB017116: , HPA048086: AB_2680257" "unprognostic (5.57e-3)" "unprognostic (8.05e-2)" "unprognostic (7.23e-2)" "unprognostic (3.87e-2)" "unprognostic (2.88e-1)" "unprognostic (2.92e-2)" "unprognostic (2.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.83e-1)" "unprognostic (5.65e-2)" "unprognostic (2.47e-1)" "unprognostic (3.44e-1)" "prognostic unfavorable (5.72e-4)" "unprognostic (6.33e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (2.03e-1)" "unprognostic (2.31e-2)" CSGALNACT1 "ChGn, CSGalNAcT-1, FLJ11264" ENSG00000147408 "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" Q8TDX6 8 19404161-19758029 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 73.3" "Cell type enhanced" "Detected in many" "Astrocytes: 468.8;Excitatory neurons: 139.3;Microglial cells: 214.7;Oligodendrocyte precursor cells: 333.9;Prostatic glandular cells: 97.2" "Cancer enhanced" "Detected in all" "prostate cancer: 22.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.0" "Group enriched" "Detected in all" 5 "B-cells: 36.7;granulocytes: 25.2;T-cells: 58.0" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 34.3" "Liver - Hepatic stellate cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068462 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" Cytosol "Golgi apparatus" "HPA068462: " "unprognostic (8.90e-2)" "unprognostic (1.57e-2)" "unprognostic (4.66e-2)" "unprognostic (2.58e-1)" "unprognostic (6.03e-2)" "unprognostic (3.17e-3)" "unprognostic (9.78e-2)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (1.46e-3)" "unprognostic (1.02e-2)" CSH1 "CSA, CSMT, FLJ75407, hCS-A, PL" ENSG00000136488 "Chorionic somatomammotropin hormone 1" P0DML2 17 63894909-63896661 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 248 "placenta: 9508.4" "Group enriched" "Detected in some" 39 "Extravillous trophoblasts: 693.8;Syncytiotrophoblasts: 1221.4" "Cancer enriched" "Detected in single" 8 "testis cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 35 "testis cancer: 15.6;Uterine cancer: 8.3" "CAB026374, HPA043715" Enhanced "Secreted to blood" Hormone NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 15: Kidney cancer - Membrane components" "Cluster 4: Extravillous trophoblasts - Unknown function" 2 "CAB026374: , HPA043715: AB_2678632" "unprognostic (6.99e-2)" CSH2 "CS-2, CSB, hCS-B" ENSG00000213218 "Chorionic somatomammotropin hormone 2" P0DML3 17 63872012-63873766 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 219 "placenta: 3198.1" "Cell type enriched" "Detected in some" 13 "Syncytiotrophoblasts: 338.3" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "testis cancer: 12.0;Uterine cancer: 8.9" HPA043715 Supported "Secreted to blood" Hormone NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 15: Kidney cancer - Membrane components" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 "HPA043715: AB_2678632" "unprognostic (1.68e-1)" "unprognostic (1.85e-1)" "unprognostic (1.86e-1)" CSHL1 "CS-5, CSHP1, CSL, hCS-L, MGC149868" ENSG00000204414 "Chorionic somatomammotropin hormone like 1" Q14406 17 63909597-63911341 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 171 "placenta: 145.3" "Cell type enriched" "Detected in single" 28 "Syncytiotrophoblasts: 19.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025646, HPA043715" Enhanced "Secreted to blood" Hormone NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 15: Kidney cancer - Membrane components" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "CAB025646: , HPA043715: AB_2678632" CSN1S1 "CASA, CSN1" ENSG00000126545 "Casein alpha s1" P47710 4 69931068-69946574 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "breast: 1342.6" "Cell type enriched" "Detected in some" 35 "Breast glandular cells: 8282.7" "Cancer enriched" "Detected in some" 10 "breast cancer: 17.1" "Region enhanced" "Detected in single" "hypothalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "thyroid cancer: 12.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035659, HPA057031" Enhanced "Secreted in female reproductive system" Other NA NA "Cluster 73: Breast - Lactation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 17: Breast glandular cells - Lactation" 1 "HPA035659: AB_10696356, HPA057031: AB_2683315" "unprognostic (1.52e-2)" "unprognostic (1.01e-1)" CSN2 CASB ENSG00000135222 "Casein beta" P05814 4 69955256-69965728 "Predicted secreted proteins" "Milk protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "breast: 560.3" "Cell type enriched" "Detected in some" 80 "Breast glandular cells: 32004.2" "Cancer enriched" "Detected in single" 156 "breast cancer: 75.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041036 Supported "Secreted in female reproductive system" Other NA NA "Cluster 73: Breast - Lactation" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 17: Breast glandular cells - Lactation" 2 "HPA041036: AB_10793865" CSN3 CSN10 ENSG00000171209 "Casein kappa" P07498 4 70238382-70251474 "Predicted secreted proteins" "Milk protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "breast: 350.7" "Cell type enriched" "Detected in some" 14 "Breast glandular cells: 2600.2" "Cancer enriched" "Detected in some" 5 "breast cancer: 35.3" "Region enhanced" "Detected in single" "midbrain: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "breast cancer: 3.6;colorectal cancer: 13.8;lung cancer: 4.8;thyroid cancer: 9.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA035953, HPA035954" Enhanced "Secreted in female reproductive system" Other NA NA "Cluster 73: Breast - Lactation" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 17: Breast glandular cells - Lactation" 5 "HPA035953: AB_10673226, HPA035954: AB_2674884" CST1 ENSG00000170373 "Cystatin SN" P01037 20 23747562-23751268 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 120 "salivary gland: 27534.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 19.1;Collecting duct cells: 81.7;Glandular and luminal cells: 34.5;Prostatic glandular cells: 61.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "pons: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 91.6;liver cancer: 120.5" "CAB026769, HPA043706, HPA044763" Enhanced "Secreted to digestive system" "Enzyme inhibitor" NA NA 6300000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 70: DU4475 - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 4 "CAB026769: , HPA043706: AB_2678627, HPA044763: AB_2679080" "prognostic favorable (4.00e-4)" "unprognostic (2.47e-1)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (1.99e-1)" "unprognostic (5.27e-2)" "unprognostic (1.99e-1)" "unprognostic (1.56e-1)" "unprognostic (1.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.34e-2)" "unprognostic (1.39e-1)" "unprognostic (8.26e-2)" "unprognostic (9.58e-2)" "unprognostic (2.58e-1)" "unprognostic (9.00e-2)" "unprognostic (9.91e-3)" CST11 "CST8L, CTES2, dJ322G13.6" ENSG00000125831 "Cystatin 11" Q9H112 20 23450403-23452876 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 476 "epididymis: 205.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.1;Endometrial stromal cells: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA053399 Enhanced "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 50: Lymphoma - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" "HPA053399: AB_2682136" "unprognostic (9.42e-2)" "unprognostic (2.21e-2)" CST2 ENSG00000170369 "Cystatin SA" P09228 20 23823769-23826729 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 638 "salivary gland: 5804.2" "Cell type enriched" "Detected in some" 15 "Serous glandular cells: 288.1" "Cancer enhanced" "Detected in many" "prostate cancer: 24.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 9.5" "CAB024963, HPA043706, HPA044763" Enhanced "Secreted to digestive system" "Enzyme inhibitor" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" 7 "CAB024963: , HPA043706: AB_2678627, HPA044763: AB_2679080" "unprognostic (1.57e-2)" "unprognostic (3.23e-2)" "unprognostic (1.04e-1)" "unprognostic (3.10e-1)" "unprognostic (1.64e-2)" "unprognostic (5.17e-3)" "unprognostic (1.28e-2)" "unprognostic (2.75e-3)" "unprognostic (2.73e-1)" "unprognostic (4.82e-3)" "unprognostic (6.43e-3)" "unprognostic (2.51e-1)" "unprognostic (4.58e-11)" "unprognostic (1.29e-3)" "unprognostic (3.22e-1)" "unprognostic (4.30e-1)" "unprognostic (1.71e-1)" CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4419.8;choroid plexus: 4010.9" "Cell type enhanced" "Detected in all" "Langerhans cells: 22281.6;Schwann cells: 10946.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4979.2;intermediate monocyte: 6434.2;myeloid DC: 7977.6;non-classical monocyte: 4321.2;plasmacytoid DC: 4438.0" "Group enriched" "Detected in all" 9 "dendritic cells: 7977.6;monocytes: 6434.2" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" "Enzyme inhibitor" NA NA 1040000000 2800000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" 1 "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" CST4 ENSG00000101441 "Cystatin S" P01036 20 23685640-23689038 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 516 "salivary gland: 28148.8" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 60.7;Prostatic glandular cells: 36.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 24.1;liver cancer: 45.0" "HPA043706, HPA044763" Supported "Secreted to digestive system" "Enzyme inhibitor" NA NA 2800000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "HPA043706: AB_2678627, HPA044763: AB_2679080" "unprognostic (2.80e-1)" "unprognostic (7.88e-2)" "unprognostic (2.48e-1)" "unprognostic (1.09e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (4.98e-5)" "unprognostic (1.00e-2)" "unprognostic (9.52e-2)" "unprognostic (2.11e-2)" "unprognostic (2.31e-1)" "unprognostic (7.95e-2)" "prognostic favorable (2.88e-4)" CST5 ENSG00000170367 "Cystatin D" P28325 20 23875934-23879748 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 961 "salivary gland: 2090.3" "Cell type enriched" "Detected in some" 38 "Serous glandular cells: 325.9" "Cancer enriched" "Detected in many" 5 "breast cancer: 17.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.0;colorectal cancer: 3.0;Esophageal cancer: 2.2" "CAB024944, HPA061449" Enhanced "Secreted to digestive system" "Enzyme inhibitor" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" "CAB024944: , HPA061449: AB_2684523" "unprognostic (2.43e-1)" "unprognostic (8.83e-2)" "unprognostic (3.20e-1)" "unprognostic (3.19e-1)" "unprognostic (1.51e-2)" "unprognostic (4.73e-1)" "unprognostic (4.31e-2)" "unprognostic (1.76e-2)" "unprognostic (2.32e-1)" "unprognostic (1.35e-1)" "unprognostic (4.83e-3)" "unprognostic (5.14e-2)" "unprognostic (2.31e-1)" CST6 ENSG00000175315 "Cystatin E/M" Q15828 11 66012008-66013505 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "skin 1: 738.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 383.3;Ciliated cells: 227.1;Mesothelial cells: 127.7;Pancreatic endocrine cells: 329.4;Suprabasal keratinocytes: 99.2" "Group enriched" "Detected in many" 5 "thyroid cancer: 171.0;urothelial cancer: 43.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 203.3;Bladder cancer: 187.9;pancreatic cancer: 182.1" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB019316, HPA044963" Enhanced Approved "Plasma membrane,Cytosol" "Secreted in other tissues" "Enzyme inhibitor" NA NA 82000000 "Cluster 13: Skin - Cornification" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane" Cytosol "CAB019316: , HPA044963: AB_2679158" "unprognostic (3.01e-2)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "unprognostic (5.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (5.02e-1)" "unprognostic (8.89e-3)" "unprognostic (1.29e-3)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (5.89e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-2)" "unprognostic (2.59e-2)" CST7 ENSG00000077984 "Cystatin F" O76096 20 24949269-24959928 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 1081.5" "Cell type enhanced" "Detected in many" "granulocytes: 261.3;Langerhans cells: 679.0;NK-cells: 1657.9;T-cells: 496.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 1290.1" "Group enriched" "Detected in all" 27 "granulocytes: 344.2;NK-cells: 657.1;T-cells: 1290.1" "Cancer enriched" "Detected in many" 4 "Leukemia: 134.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Skeletal muscle - Neutrophils, Thyroid - T-cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Low region specificity" "Detected in all" HPA040442 Enhanced "Secreted to blood" "Enzyme inhibitor" NA NA 26000 "Cluster 1: T-cells - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" "HPA040442: AB_2676988" "prognostic favorable (6.55e-4)" "prognostic favorable (7.90e-4)" "unprognostic (9.37e-2)" "prognostic favorable (9.17e-6)" "unprognostic (2.38e-2)" "prognostic favorable (5.85e-5)" "unprognostic (1.00e-2)" "unprognostic (8.66e-2)" "unprognostic (2.84e-3)" "unprognostic (7.93e-2)" "unprognostic (5.05e-2)" "unprognostic (7.42e-2)" "prognostic unfavorable (4.37e-6)" "unprognostic (7.64e-2)" "unprognostic (3.38e-1)" "unprognostic (4.45e-1)" "unprognostic (7.62e-2)" CST8 "CRES, CTES5" ENSG00000125815 "Cystatin 8" O60676 20 23491101-23496010 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 204 "testis: 21.7" "Group enriched" "Detected in some" 182 "Early spermatids: 111.5;Late spermatids: 179.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 50: Lymphoma - Unknown function" "Cluster 13: Spermatids - Transcription" CST9 "CLM, CTES7A" ENSG00000173335 "Cystatin 9" Q5W186 20 23602410-23605917 "Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "breast: 1.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 37 "breast cancer: 9.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "breast cancer: 1.7" "Breast - Breast glandular cells" HPA029190 Uncertain "Secreted in female reproductive system" "Enzyme inhibitor" NA NA "Cluster 73: Breast - Lactation" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "HPA029190: AB_10602804" "unprognostic (2.06e-2)" "unprognostic (2.21e-4)" CST9L "bA218C14.1, CTES7B" ENSG00000101435 "Cystatin 9 like" Q9H4G1 20 23564732-23568484 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 339 "epididymis: 25.7;testis: 85.2" "Cell type enhanced" "Detected in some" "Early spermatids: 2.6;Late spermatids: 9.7;Leydig cells: 2.0;Peritubular cells: 1.6;Sertoli cells: 10.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 63: Testis - Spermatid development" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 6 "unprognostic (2.10e-2)" CSTL1 "CTES1, dJ322G13.4" ENSG00000125823 "Cystatin like 1" Q9H114 20 23426104-23444930 "Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 14 "testis: 1.7" "Group enriched" "Detected in some" 59 "Early spermatids: 28.2;Late spermatids: 87.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 20: Testis - Spermatogenesis" "Cluster 56: Non-specific - Sensory perception" "Cluster 11: Late spermatids - Unknown function" "unprognostic (1.14e-1)" "unprognostic (1.54e-1)" "unprognostic (3.25e-3)" "unprognostic (2.04e-1)" "unprognostic (6.58e-2)" "unprognostic (2.68e-1)" "unprognostic (1.61e-1)" "unprognostic (5.40e-2)" "unprognostic (3.63e-1)" "unprognostic (2.97e-1)" "unprognostic (6.87e-2)" "unprognostic (2.35e-1)" "unprognostic (5.36e-2)" CT55 "CXorf48, FLJ20527" ENSG00000169551 "Cancer/testis antigen 55" Q8WUE5 X 135156540-135171398 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 3.7" "Group enriched" "Detected in some" 41 "Spermatocytes: 58.9;Spermatogonia: 32.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.7;Sarcoma: 3.7;skin cancer: 7.1" "Testis - Spermatocytes" HPA059575 Approved Vesicles "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 22 Vesicles "HPA059575: " "unprognostic (6.20e-2)" "unprognostic (1.39e-1)" "unprognostic (8.36e-2)" "unprognostic (5.86e-3)" "unprognostic (3.47e-1)" "unprognostic (2.67e-1)" "unprognostic (4.44e-2)" "unprognostic (1.49e-1)" CTBS CTB ENSG00000117151 Chitobiase Q01459 1 84549611-84574480 "Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "monocytes: 66.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 7 "basal ganglia: 9.8" "CAB017043, HPA023594, HPA048810" Approved Uncertain Cytosol "Intracellular and membrane" Enzyme NA NA 370000000 "Cluster 53: Non-specific - Glycosylation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 74: Neutrophils - Degranulation" Cytosol "CAB017043: , HPA023594: AB_1847311, HPA048810: " "unprognostic (7.76e-2)" "unprognostic (1.28e-2)" "unprognostic (1.11e-1)" "unprognostic (1.36e-1)" "unprognostic (9.36e-2)" "unprognostic (3.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.76e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (9.23e-2)" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.08e-2)" "unprognostic (4.89e-2)" "unprognostic (3.12e-1)" "unprognostic (4.04e-2)" CTF1 "CT-1, CT1" ENSG00000150281 "Cardiotrophin 1" Q16619 16 30896614-30903547 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 15.0;Distal tubular cells: 27.7;Muller glia cells: 19.6;Proximal tubular cells: 13.9;Secretory cells: 20.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025853 Uncertain "Secreted to blood" Cytokine NA NA 11900 "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "CAB025853: " "unprognostic (1.31e-1)" "unprognostic (9.01e-2)" "unprognostic (6.81e-3)" "unprognostic (1.06e-3)" "prognostic unfavorable (7.22e-5)" "unprognostic (2.12e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.87e-4)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (6.75e-2)" "unprognostic (2.76e-2)" "unprognostic (1.76e-3)" "unprognostic (5.07e-3)" "unprognostic (2.06e-1)" "unprognostic (2.16e-2)" "unprognostic (1.79e-1)" CTHRC1 ENSG00000164932 "Collagen triple helix repeat containing 1" Q96CG8 8 103371538-103382989 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 66.9;gallbladder: 84.7;placenta: 87.0;urinary bladder: 81.5" "Cell type enhanced" "Detected in many" "Endothelial cells: 71.5;Fibroblasts: 157.4;Lymphatic endothelial cells: 71.2;Pancreatic endocrine cells: 67.9;Smooth muscle cells: 57.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "skin cancer: 166.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059806, HPA061896" Approved Approved Nucleoplasm "Secreted in other tissues" "No annotated function" NA NA 420000 "Cluster 58: Placenta - Pregnancy" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" Nucleoplasm "HPA059806: AB_2684130, HPA061896: AB_2684633" "unprognostic (2.04e-2)" "unprognostic (4.58e-1)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.17e-2)" "unprognostic (3.64e-2)" "unprognostic (8.63e-2)" "unprognostic (1.12e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.22e-14)" "unprognostic (2.33e-3)" "unprognostic (3.21e-2)" "unprognostic (7.96e-3)" "unprognostic (2.37e-3)" CTRB1 CTRB ENSG00000168925 "Chymotrypsinogen B1" P17538 16 75218988-75226338 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5240 "pancreas: 129624.7" "Cell type enriched" "Detected in some" 23 "Exocrine glandular cells: 15190.7" "Cancer enriched" "Detected in some" 1905 "pancreatic cancer: 962.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" Enzyme NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "unprognostic (1.76e-1)" "unprognostic (2.62e-1)" "unprognostic (3.55e-1)" "unprognostic (1.57e-1)" "unprognostic (5.22e-2)" "unprognostic (4.43e-3)" "unprognostic (2.96e-1)" "unprognostic (1.17e-2)" CTRB2 ENSG00000168928 "Chymotrypsinogen B2" Q6GPI1 16 75204103-75207161 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 3540 "pancreas: 95538.0" "Cell type enriched" "Detected in some" 9 "Exocrine glandular cells: 29617.7" "Cancer enriched" "Detected in single" 1696 "pancreatic cancer: 540.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" Enzyme NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "unprognostic (9.41e-4)" "unprognostic (2.20e-1)" "unprognostic (1.28e-2)" "unprognostic (2.10e-1)" "unprognostic (2.92e-2)" "unprognostic (2.77e-1)" "unprognostic (5.95e-2)" "unprognostic (9.56e-2)" "unprognostic (3.54e-3)" "unprognostic (7.06e-2)" "unprognostic (2.17e-1)" "unprognostic (7.57e-2)" CTRC "CLCR, ELA4" ENSG00000162438 "Chymotrypsin C" Q99895 1 15438442-15449242 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 3944 "pancreas: 24975.6" "Cell type enriched" "Detected in some" 14 "Exocrine glandular cells: 3609.8" "Cancer enriched" "Detected in some" 168 "pancreatic cancer: 236.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" HPA046920 Enhanced "Secreted to digestive system" Enzyme NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 12 "HPA046920: AB_2679865" "unprognostic (2.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (8.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (2.94e-2)" "unprognostic (7.60e-2)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-11)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.50e-1)" "unprognostic (5.99e-3)" CTRL ENSG00000141086 "Chymotrypsin like" P40313 16 67927640-67932365 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1187 "pancreas: 7243.2" "Cell type enriched" "Detected in some" 18 "Exocrine glandular cells: 156.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034504, HPA034505" Enhanced "Secreted to digestive system" Enzyme NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 3 "HPA034504: AB_2674196, HPA034505: AB_10602212" "unprognostic (3.03e-5)" "unprognostic (3.53e-3)" "unprognostic (3.46e-2)" "unprognostic (1.37e-1)" "unprognostic (9.66e-2)" "unprognostic (2.00e-2)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (6.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.88e-1)" "unprognostic (3.20e-4)" "unprognostic (6.69e-2)" "unprognostic (2.79e-1)" "unprognostic (2.63e-1)" "unprognostic (1.29e-3)" CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 356.8" "Cell type enhanced" "Detected in all" "Distal enterocytes: 353.1;Hofbauer cells: 295.6;Proximal enterocytes: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" Enzyme NA NA 28000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 57: Platelets - Hemostasis" 2 Vesicles "CAB024930: , HPA031068: AB_10601205, HPA072487: " "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2488.5;Kupffer cells: 2037.4;Macrophages: 1463.1" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 389.7;classical monocyte: 610.5;intermediate monocyte: 467.6;myeloid DC: 287.7;non-classical monocyte: 309.1;plasmacytoid DC: 410.8" "Group enriched" "Detected in all" 6 "dendritic cells: 410.8;granulocytes: 389.7;monocytes: 610.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" Enzyme NA NA 100000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 7: Adipose tissue - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 4 Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 879.8;Club cells: 507.1;Hofbauer cells: 1008.0;Ionocytes: 520.6;Macrophages: 465.3;monocytes: 724.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" Enzyme No No 19000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 57: Lung - Lung function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles "CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favorable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1368.7;Hofbauer cells: 3533.1;Macrophages: 1286.5;Proximal enterocytes: 1589.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000109, HPA003001" Supported "Secreted to blood" Enzyme NA NA 370000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" 22 "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" CTSE ENSG00000196188 "Cathepsin E" P14091 1 206008535-206023909 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 1138.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 553.6;Alveolar cells type 2: 190.6;Exocrine glandular cells: 130.0;Gastric mucus-secreting cells: 626.1;Paneth cells: 256.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 297.4;stomach cancer: 200.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 28.4;Esophageal cancer: 48.8;Gastric cancer: 110.7;pancreatic cancer: 35.3" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA012674, HPA012940, CAB032687" Enhanced Approved Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" Vesicles "CAB032687: AB_637901, HPA012674: , HPA012940: AB_2668773" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-2)" "unprognostic (2.72e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-3)" "unprognostic (1.45e-1)" "unprognostic (3.29e-2)" "unprognostic (2.87e-2)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "unprognostic (6.37e-3)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (2.61e-2)" "prognostic favorable (5.26e-5)" CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563464-66568879 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 316.7;Melanocytes: 211.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA 5800000 "Cluster 27: T-cells - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 69: Skin cancer - ECM organization" "Cluster 6: Ovarian stromal cells - Transcription" Vesicles "Endoplasmic reticulum, Plasma membrane" "CAB002141: AB_563471, HPA031431: " "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-3)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.76e-2)" "unprognostic (3.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.69e-2)" "unprognostic (9.12e-2)" "prognostic favorable (8.92e-7)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (2.42e-1)" CTSG CG ENSG00000100448 "Cathepsin G" P08311 14 24573518-24576250 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Chemotaxis "Antibiotic, Antimicrobial, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 157 "bone marrow: 5283.5" "Cell type enriched" "Detected in some" 23 "granulocytes: 687.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 430 "Leukemia: 517.5" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Neutrophil_1, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000110, HPA047737" Enhanced "Intracellular and membrane" Enzyme NA NA 330000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 4 "CAB000110: , HPA047737: AB_2680140" "unprognostic (1.67e-1)" "unprognostic (2.57e-2)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "prognostic favorable (1.57e-4)" "unprognostic (4.05e-2)" "unprognostic (4.13e-2)" "unprognostic (3.06e-1)" "unprognostic (2.42e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" "unprognostic (1.63e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.91e-4)" CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 338.6" "Cell type enriched" "Detected in all" 5 "Alveolar cells type 2: 1759.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 209.6;intermediate monocyte: 138.1;memory B-cell: 83.8;myeloid DC: 184.0;naive B-cell: 56.3;non-classical monocyte: 95.3" "Group enriched" "Detected in all" 5 "B-cells: 83.8;dendritic cells: 184.0;monocytes: 209.6" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" Enzyme NA NA 8700000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 47: Spleen - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 2 "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 407.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 319.3;Langerhans cells: 84.8;Leydig cells: 121.2;Peritubular cells: 148.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 16 "choroid plexus: 31.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Lineage enriched" "Detected in single" 5 "monocytes: 1.9" "Cancer enriched" "Detected in many" 5 "skin cancer: 65.3" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 544.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1104.2;Extravillous trophoblasts: 1194.3;Hofbauer cells: 1034.6;Macrophages: 600.4;Syncytiotrophoblasts: 1853.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.2;non-classical monocyte: 196.2" "Lineage enriched" "Detected in many" 12 "monocytes: 196.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Pancreas - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 17000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" 1 "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" CTSO CTSO1 ENSG00000256043 "Cathepsin O" P43234 4 155921580-155953912 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002041 Approved "Intracellular and membrane" Enzyme NA NA 25000 "Cluster 24: Non-specific - Transcription" "Cluster 11: Liver - Plasma proteins" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Fibroblasts - ECM organization" 3 "HPA002041: AB_1078408" "unprognostic (3.96e-3)" "unprognostic (1.62e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-2)" "unprognostic (9.10e-3)" "unprognostic (2.55e-1)" "unprognostic (3.80e-3)" "unprognostic (2.07e-1)" "unprognostic (6.62e-2)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.05e-1)" "unprognostic (7.55e-2)" "unprognostic (4.87e-3)" "unprognostic (4.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 127.8;lymphoid tissue: 160.8" "Group enriched" "Detected in many" 4 "Hofbauer cells: 1232.7;Kupffer cells: 2021.4;Macrophages: 1270.0;monocytes: 3727.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2462.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 35.9;Myeloma: 33.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" Enzyme NA NA 23000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029677-97156556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 626.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 67.3;Cytotrophoblasts: 135.0;Extravillous trophoblasts: 178.7;Rod photoreceptor cells: 93.7;Sertoli cells: 149.6;Syncytiotrophoblasts: 73.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.2" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.2" "Cancer enriched" "Detected in all" 7 "testis cancer: 681.3" "Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 370000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavorable (2.39e-4)" CTSW ENSG00000172543 "Cathepsin W" P56202 11 65879809-65883741 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 114.6;lymphoid tissue: 41.3" "Group enriched" "Detected in many" 7 "NK-cells: 907.3;T-cells: 310.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "gdT-cell: 1379.5;MAIT T-cell: 871.1;memory CD8 T-cell: 892.9;naive CD8 T-cell: 638.1;NK-cell: 2280.8" "Group enriched" "Detected in all" 39 "NK-cells: 2280.8;T-cells: 1379.5" "Cancer enriched" "Detected in some" 16 "Leukemia: 40.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB016345, HPA066903" Enhanced "Intracellular and membrane" Enzyme NA NA 270000 "Cluster 15: NK-cells - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" "CAB016345: AB_626813, HPA066903: " "prognostic favorable (3.06e-4)" "unprognostic (2.06e-2)" "unprognostic (2.71e-2)" "prognostic favorable (8.36e-6)" "unprognostic (1.21e-1)" "prognostic favorable (9.89e-4)" "unprognostic (5.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (5.14e-3)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (8.84e-6)" "unprognostic (3.86e-2)" "unprognostic (3.78e-1)" "unprognostic (1.26e-1)" "unprognostic (4.01e-3)" CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 986.2;Langerhans cells: 1144.6;Macrophages: 766.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" Enzyme NA NA 88000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 47: Spleen - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" 16 Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" CUBN "gp280, IFCR, MGA1" ENSG00000107611 Cubilin O60494 10 16823966-17129811 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Protein transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 135.4" "Group enriched" "Detected in many" 6 "Proximal enterocytes: 186.0;Proximal tubular cells: 276.0" "Cancer enriched" "Detected in some" 15 "renal cancer: 24.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 17.7" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004133, HPA043854" Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Proximal tubular cells - Transmembrane transport" 2 "HPA004133: AB_2732398, HPA043854: AB_2732510" "unprognostic (1.75e-1)" "unprognostic (2.35e-1)" "unprognostic (2.12e-3)" "unprognostic (8.61e-4)" "unprognostic (9.54e-2)" "unprognostic (2.78e-2)" "unprognostic (2.88e-2)" "unprognostic (7.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.47e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.24e-3)" "unprognostic (1.97e-1)" "unprognostic (2.00e-1)" "unprognostic (1.93e-1)" CUTA "ACHAP, C6orf82" ENSG00000112514 "CutA divalent cation tolerance homolog" O60888 6 33416442-33418317 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016787, HPA064369, HPA070199" Approved Approved "Plasma membrane,Focal adhesion sites" "Secreted to blood" "No annotated function" NA NA 26000000 "Cluster 39: T-cells - T-cell receptor" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Ribosome" 2 "Plasma membrane, Focal adhesion sites" "CAB016787: , HPA064369: AB_2685248, HPA070199: " "unprognostic (7.03e-2)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (8.91e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.98e-2)" "prognostic favorable (8.50e-4)" "unprognostic (1.87e-1)" "unprognostic (2.78e-2)" "unprognostic (1.27e-3)" "unprognostic (1.91e-1)" "unprognostic (5.55e-2)" "unprognostic (9.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (2.74e-1)" CX3CL1 "ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1" ENSG00000006210 "C-X3-C motif chemokine ligand 1" P78423 16 57372477-57385044 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Chemotaxis, Host-virus interaction, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 112.5;Basal respiratory cells: 55.0;Breast glandular cells: 62.9;Club cells: 53.3;Endothelial cells: 54.3;Ionocytes: 113.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026192, HPA040361, CAB080311" Approved Supported "Plasma membrane" "Secreted to blood" Chemokine NA NA 1870000 370000 "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Plasma membrane" "CAB026192: , CAB080311: , HPA040361: AB_10796453" "unprognostic (6.89e-3)" "prognostic favorable (9.46e-4)" "unprognostic (1.52e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (7.12e-2)" "unprognostic (2.08e-3)" "unprognostic (4.49e-2)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-2)" "prognostic favorable (8.52e-7)" "unprognostic (5.19e-2)" "unprognostic (2.72e-1)" "unprognostic (1.11e-2)" "unprognostic (9.33e-2)" CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 51.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 235.9;Proximal enterocytes: 218.0;Suprabasal keratinocytes: 220.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Secreted - unknown location" Receptor NA NA 18000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "Plasma membrane, Cell Junctions" Nucleoplasm "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" CXCL1 "FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1" ENSG00000163739 "C-X-C motif chemokine ligand 1" P09341 4 73869393-73871308 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 98.5;lymphoid tissue: 191.9" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 18250.8;Ionocytes: 13731.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 244 "neutrophil: 47.5" "Lineage enriched" "Detected in single" 244 "granulocytes: 47.5" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Secreted to blood" Chemokine NA NA 384000 "Cluster 4: Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "prognostic favorable (7.83e-4)" "prognostic unfavorable (7.23e-4)" "unprognostic (5.24e-3)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.23e-3)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (5.45e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.17e-1)" "unprognostic (5.30e-2)" "unprognostic (7.41e-2)" "unprognostic (9.41e-2)" CXCL10 "C7, crg-2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10" ENSG00000169245 "C-X-C motif chemokine ligand 10" P02778 4 76021118-76023497 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 92.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 48.6;Langerhans cells: 29.0;Macrophages: 42.5;monocytes: 165.4;Secretory cells: 71.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "pons: 21.6" "Group enriched" "Detected in many" 11 "classical monocyte: 21.6;intermediate monocyte: 52.5;non-classical monocyte: 37.1" "Lineage enriched" "Detected in many" 15 "monocytes: 52.5" "Group enriched" "Detected in many" 6 "head and neck cancer: 8.1;lymphoma: 30.7" "Breast - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" Chemokine NA NA 253000 "Cluster 40: Monocytes - Innate immune response" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" 4 "unprognostic (1.94e-1)" "unprognostic (5.32e-2)" "unprognostic (9.98e-3)" "unprognostic (6.30e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" "unprognostic (7.59e-2)" "prognostic favorable (1.12e-5)" "prognostic unfavorable (4.61e-4)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (1.03e-1)" "unprognostic (4.95e-2)" "unprognostic (1.73e-2)" "unprognostic (1.66e-2)" CXCL11 "b-R1, H174, I-TAC, IP-9, SCYB11, SCYB9B" ENSG00000169248 "C-X-C motif chemokine ligand 11" O14625 4 76033682-76041415 "Human disease related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.7;Macrophages: 3.8;monocytes: 3.5;Secretory cells: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 6.2;head and neck cancer: 10.0" "Adipose visceral - T-cells" "Region enhanced" "Detected in single" "spinal cord: 1.7" CAB009921 Uncertain "Secreted to blood" Chemokine NA NA 187000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 5 "CAB009921: AB_2088137" "unprognostic (2.00e-1)" "unprognostic (3.62e-1)" "unprognostic (6.94e-3)" "unprognostic (1.87e-2)" "unprognostic (9.95e-2)" "unprognostic (5.85e-2)" "unprognostic (1.89e-1)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "prognostic favorable (4.31e-7)" "prognostic unfavorable (8.18e-5)" "unprognostic (2.90e-1)" "prognostic unfavorable (3.29e-6)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (4.48e-2)" "unprognostic (5.32e-2)" CXCL12 "PBSF, SCYB12, SDF-1a, SDF-1b, SDF1, SDF1A, SDF1B, TLSF-a, TLSF-b, TPAR1" ENSG00000107562 "C-X-C motif chemokine ligand 12" P48061 10 44370165-44386493 "Predicted secreted proteins" "Chemotaxis, Host-virus interaction" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 293.2;Distal tubular cells: 116.8;Endothelial cells: 130.5;Fibroblasts: 451.4;Kupffer cells: 159.0;Smooth muscle cells: 131.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 60.3;testis cancer: 57.1" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017564 Approved "Secreted to blood" Chemokine NA NA 1030000 560000 "Cluster 62: Connective tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 19 "CAB017564: AB_2088170" "unprognostic (2.41e-1)" "unprognostic (2.95e-2)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-2)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (3.28e-3)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-1)" "unprognostic (1.08e-1)" "unprognostic (5.95e-3)" CXCL13 "ANGIE, ANGIE2, BCA-1, BLC, BLR1L, SCYB13" ENSG00000156234 "C-X-C motif chemokine ligand 13" O43927 4 77511753-77611834 "Cancer-related genes, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 529.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 210.4;Breast myoepithelial cells: 39.9;Endometrial stromal cells: 103.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "medulla oblongata: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "lymphoma: 5.1;thyroid cancer: 9.7" "Thyroid - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052613 Uncertain "Secreted to blood" Chemokine NA NA 93700 "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 9: Endometrial stromal cells - Transcription" "HPA052613: AB_2681885" "unprognostic (5.25e-3)" "unprognostic (1.19e-2)" "prognostic favorable (9.12e-4)" "prognostic favorable (5.52e-4)" "unprognostic (1.53e-2)" "unprognostic (1.17e-3)" "unprognostic (1.49e-1)" "unprognostic (6.41e-3)" "unprognostic (9.82e-3)" "prognostic favorable (5.41e-4)" "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (1.16e-10)" "unprognostic (2.04e-2)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (6.68e-3)" CXCL14 "BMAC, bolekine, BRAK, Kec, KS1, MIP-2g, NJAC, SCYB14" ENSG00000145824 "C-X-C motif chemokine ligand 14" O95715 5 135570679-135579279 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 760.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2219.3;Basal squamous epithelial cells: 1365.1;Breast myoepithelial cells: 1727.3;Fibroblasts: 1464.0;Glandular and luminal cells: 1597.2;Proximal tubular cells: 3421.8;Suprabasal keratinocytes: 1266.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 150.2;head and neck cancer: 209.2" "Breast - Breast myoepithelial cells, Kidney - Proximal tubular cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB029996 Uncertain "Secreted to blood" Chemokine NA NA 800000 "Cluster 13: Skin - Cornification" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Fibroblasts - ECM organization" 5 "CAB029996: AB_2086070" "unprognostic (1.82e-3)" "prognostic favorable (1.71e-4)" "prognostic favorable (4.52e-4)" "unprognostic (2.75e-2)" "unprognostic (2.71e-3)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (9.05e-2)" "unprognostic (2.22e-2)" "unprognostic (5.34e-2)" "unprognostic (1.26e-1)" "unprognostic (9.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.48e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" CXCL16 "CXCLG16, SR-PSOX, SRPSOX" ENSG00000161921 "C-X-C motif chemokine ligand 16" Q9H2A7 17 4733533-4739928 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 4051.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 63.2;intermediate monocyte: 107.3;myeloid DC: 38.2;neutrophil: 103.3;non-classical monocyte: 141.8" "Group enriched" "Detected in many" 7 "dendritic cells: 38.2;granulocytes: 103.3;monocytes: 141.8" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053253, HPA066315" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" Chemokine NA NA 1100000 6800000 "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Testis - Spermatogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" "Golgi apparatus" Vesicles "HPA053253: AB_2682091, HPA066315: AB_2685657" "unprognostic (4.64e-3)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (3.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.24e-1)" "unprognostic (4.05e-1)" "unprognostic (4.22e-2)" "unprognostic (2.08e-1)" "unprognostic (4.78e-2)" "unprognostic (4.74e-2)" "unprognostic (2.37e-2)" "unprognostic (2.48e-2)" "unprognostic (2.60e-1)" CXCL17 "Dcip1, DMC, UNQ473, VCC1" ENSG00000189377 "C-X-C motif chemokine ligand 17" Q6UXB2 19 42428278-42442946 "Predicted secreted proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 117.2;lung: 144.3;salivary gland: 141.3;stomach 1: 348.8" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 626.0;Basal respiratory cells: 1184.3;Club cells: 1204.1;Ionocytes: 2433.8" "Cancer enhanced" "Detected in many" "cervical cancer: 170.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 17.2;Gastric cancer: 8.7;lung cancer: 8.6" "Lung - Alveolar cells type 2, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted to blood" "Developmental protein" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 34: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 3 "unprognostic (2.74e-1)" "unprognostic (3.96e-2)" "unprognostic (2.78e-1)" "unprognostic (1.03e-2)" "unprognostic (4.46e-3)" "unprognostic (3.77e-1)" "prognostic favorable (4.92e-5)" "unprognostic (6.68e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.70e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-1)" "unprognostic (1.88e-1)" "unprognostic (8.13e-3)" "unprognostic (2.29e-1)" CXCL2 "CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, SCYB2" ENSG00000081041 "C-X-C motif chemokine ligand 2" P19875 4 74097040-74099196 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 497.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1419.5;Basal respiratory cells: 3098.3;Ionocytes: 2347.3;Langerhans cells: 2541.9;monocytes: 2355.2;Secretory cells: 2445.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 1.1;non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 10 "monocytes: 1.1" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Secreted to blood" Chemokine NA NA "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 4 "prognostic favorable (5.93e-5)" "prognostic unfavorable (1.41e-4)" "unprognostic (5.28e-3)" "unprognostic (1.36e-1)" "unprognostic (2.64e-3)" "unprognostic (1.27e-1)" "unprognostic (7.14e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (6.72e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.07e-6)" "unprognostic (1.05e-2)" "unprognostic (2.33e-1)" "unprognostic (2.11e-1)" "unprognostic (1.59e-1)" CXCL3 "CINC-2b, GRO3, GROg, MIP-2b, SCYB3" ENSG00000163734 "C-X-C motif chemokine ligand 3" P19876 4 74036589-74038807 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 20.1;cervix: 19.9" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 2454.4;Ionocytes: 1635.3;Langerhans cells: 2799.8;Macrophages: 1042.5;monocytes: 2225.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.4;stomach cancer: 18.2" "Group enriched" "Detected in some" 6 "cerebral cortex: 4.0;thalamus: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Secreted to blood" Chemokine NA NA 28700 "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" "unprognostic (2.12e-3)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.08e-3)" "unprognostic (6.97e-3)" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-4)" "unprognostic (2.45e-2)" "unprognostic (2.24e-1)" "unprognostic (2.68e-1)" "unprognostic (9.69e-2)" "unprognostic (1.81e-1)" "unprognostic (2.89e-6)" "unprognostic (2.61e-3)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (1.20e-1)" CXCL5 "ENA-78, SCYB5" ENSG00000163735 "C-X-C motif chemokine ligand 5" P42830 4 73995642-73998677 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 34.9;salivary gland: 48.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 84.7;Ductal cells: 71.1;Langerhans cells: 45.0;Macrophages: 161.4;Mucus glandular cells: 138.3;Pancreatic endocrine cells: 39.1" "Group enriched" "Detected in many" 4 "pancreatic cancer: 56.2;stomach cancer: 74.0" "Region enhanced" "Detected in many" "cerebral cortex: 19.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 162.1" "Testis - Spermatogonia" HPA065474 Approved Approved Vesicles "Secreted to blood" Chemokine NA NA 1110000 1600000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 5 Vesicles "HPA065474: AB_2685494" "unprognostic (5.56e-3)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.80e-2)" "unprognostic (1.43e-2)" "unprognostic (2.04e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.06e-2)" "unprognostic (3.04e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (7.99e-2)" "prognostic unfavorable (2.45e-5)" "unprognostic (3.72e-1)" "unprognostic (3.07e-1)" "unprognostic (2.72e-2)" "unprognostic (9.30e-2)" CXCL6 "CKA-3, GCP-2, SCYB6" ENSG00000124875 "C-X-C motif chemokine ligand 6" P80162 4 73836640-73849064 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 34.9;lymphoid tissue: 98.2;urinary bladder: 25.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 613.5;Cholangiocytes: 291.9;Club cells: 229.2;Ductal cells: 1061.5;Ionocytes: 339.1;Pancreatic endocrine cells: 176.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 9.7;choroid plexus: 4.9" "Immune cell enriched" "Detected in single" 105 "neutrophil: 10.4" "Lineage enriched" "Detected in single" 105 "granulocytes: 10.4" "Group enriched" "Detected in many" 10 "Kidney cancer: 181.9;thyroid cancer: 141.4" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Testis - Spermatogonia" "Region enhanced" "Detected in many" "basal ganglia: 9.6" "Not detected" "Not detected" "Secreted to blood" Chemokine NA NA 108000 "Cluster 4: Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 3 "unprognostic (4.35e-4)" "unprognostic (4.47e-2)" "unprognostic (6.09e-2)" "unprognostic (4.60e-2)" "unprognostic (1.98e-2)" "unprognostic (1.17e-1)" "unprognostic (3.49e-3)" "unprognostic (2.62e-1)" "unprognostic (2.05e-1)" "unprognostic (2.02e-2)" "unprognostic (3.75e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.47e-1)" "unprognostic (4.88e-1)" "unprognostic (2.72e-1)" "unprognostic (4.48e-2)" CXCL8 "3-10C, AMCF-I, b-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1" ENSG00000169429 "C-X-C motif chemokine ligand 8" P10145 4 73740519-73743716 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3130.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5750.7;Ionocytes: 4495.1;Langerhans cells: 18896.7;Macrophages: 3724.4;monocytes: 4451.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 10 "cerebral cortex: 274.2" "Immune cell enriched" "Detected in some" 408 "neutrophil: 439.6" "Lineage enriched" "Detected in single" 1040 "granulocytes: 439.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 314.5" "Pancreas - Ductal cells" "Not detected" "Not detected" HPA057179 Supported Approved "Golgi apparatus" "Secreted to blood" Chemokine NA NA 7260 "Cluster 4: Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 3 "Golgi apparatus" "HPA057179: AB_2683362" "unprognostic (3.42e-1)" "prognostic unfavorable (1.18e-5)" "unprognostic (3.91e-3)" "unprognostic (8.49e-2)" "unprognostic (3.29e-2)" "unprognostic (3.03e-3)" "prognostic unfavorable (1.19e-5)" "unprognostic (1.37e-3)" "unprognostic (3.19e-1)" "unprognostic (4.46e-1)" "unprognostic (7.19e-3)" "unprognostic (7.16e-2)" "prognostic unfavorable (3.13e-6)" "unprognostic (4.73e-2)" "unprognostic (8.57e-2)" "unprognostic (1.64e-2)" "unprognostic (6.15e-2)" CXCL9 "CMK, crg-10, Humig, MIG, SCYB9" ENSG00000138755 "C-X-C motif chemokine ligand 9" Q07325 4 76001275-76007509 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 302.7" "Cell type enhanced" "Detected in some" "Kupffer cells: 5.7;Macrophages: 16.9;monocytes: 12.6;Schwann cells: 28.9;Smooth muscle cells: 7.0;Spermatogonia: 8.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 6 "medulla oblongata: 3.8;pons: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 1.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" Chemokine NA NA 902000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" 44 "prognostic favorable (6.36e-4)" "unprognostic (6.86e-3)" "unprognostic (1.25e-2)" "prognostic favorable (2.07e-4)" "unprognostic (2.97e-1)" "unprognostic (3.78e-3)" "unprognostic (8.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.46e-2)" "prognostic favorable (8.06e-4)" "unprognostic (2.18e-3)" "unprognostic (1.88e-1)" "prognostic unfavorable (5.15e-6)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (1.57e-2)" "unprognostic (6.54e-2)" CYB5D2 MGC32124 ENSG00000167740 "Cytochrome b5 domain containing 2" Q8WUJ1 17 4143168-4187310 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 113.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011032, HPA042299" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" Other NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "Endoplasmic reticulum, Plasma membrane" "HPA011032: , HPA042299: AB_10793879" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (4.16e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.88e-2)" "unprognostic (1.75e-2)" "prognostic favorable (4.98e-6)" "unprognostic (1.57e-1)" "unprognostic (2.47e-1)" "unprognostic (9.71e-3)" "prognostic favorable (7.76e-5)" "unprognostic (2.04e-1)" "prognostic favorable (2.03e-10)" "unprognostic (2.01e-3)" "unprognostic (8.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.97e-1)" CYP17A1 "CPT7, CYP17, P450C17, S17AH" ENSG00000148795 "Cytochrome P450 family 17 subfamily A member 1" P05093 10 102830531-102837472 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroidogenesis" "Lyase, Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 83 "adrenal gland: 7970.9" "Group enriched" "Detected in some" 7 "Early spermatids: 28.9;Late spermatids: 21.8;Proximal tubular cells: 83.4" "Cancer enriched" "Detected in many" 5 "liver cancer: 22.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048533 Enhanced Approved Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 70: DU4475 - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Vesicles "HPA048533: AB_2680432" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (3.01e-2)" "unprognostic (9.08e-2)" "unprognostic (1.91e-1)" "unprognostic (6.29e-2)" "unprognostic (2.92e-3)" "unprognostic (2.39e-4)" "unprognostic (8.26e-2)" "unprognostic (2.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.43e-7)" "unprognostic (1.07e-1)" "unprognostic (5.56e-2)" "unprognostic (1.66e-2)" "unprognostic (2.94e-4)" CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3;skin 1: 30.4" "Group enriched" "Detected in many" 5 "Leydig cells: 78.3;Peritubular cells: 217.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "pons: 111.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 38.6" "Breast - Adipocytes (Breast), Liver - Vascular Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012567 Uncertain Approved Cytosol "Intracellular and membrane" Enzyme No No "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" 1 Cytosol "HPA012567: AB_1847429" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (2.19e-4)" "unprognostic (3.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.17e-4)" "unprognostic (8.41e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (7.55e-3)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (9.44e-3)" "unprognostic (2.04e-2)" CYP2A13 "CPAD, CYP2A" ENSG00000197838 "Cytochrome P450 family 2 subfamily A member 13" Q16696 19 41088451-41096195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "liver: 2.0" "Cell type enriched" "Detected in some" 5 "Club cells: 29.7" "Cancer enriched" "Detected in single" 5 "liver cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Lung - Respiratory ciliated cells" "HPA046713, HPA047262" Supported "Intracellular and membrane" Enzyme NA NA "Cluster 83: Liver - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (9.79e-2)" "unprognostic (1.00e-1)" "unprognostic (4.51e-3)" "unprognostic (4.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.49e-1)" CYP2A6 "CPA6, CYP2A, CYP2A3" ENSG00000255974 "Cytochrome P450 family 2 subfamily A member 6" P11509 19 40843541-40850447 "Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 170 "liver: 1564.1" "Cell type enriched" "Detected in some" 37 "Hepatocytes: 160.7" "Cancer enriched" "Detected in some" 12 "liver cancer: 281.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Lung - Respiratory ciliated cells" "HPA046713, HPA047262" Supported "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 27: Breast cancer - Unknown function" "Cluster 43: Hepatocytes - Metabolism" "HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (5.40e-2)" "unprognostic (2.36e-2)" "unprognostic (1.21e-1)" "unprognostic (4.10e-1)" "unprognostic (5.05e-2)" "unprognostic (2.64e-2)" "prognostic favorable (5.38e-5)" "unprognostic (4.98e-3)" "unprognostic (4.86e-2)" "unprognostic (6.23e-2)" "unprognostic (5.20e-2)" "unprognostic (1.95e-1)" "unprognostic (2.25e-2)" "unprognostic (8.83e-3)" "unprognostic (2.46e-1)" "unprognostic (3.07e-2)" "unprognostic (2.55e-1)" CYP2A7 CYP2A ENSG00000198077 "Cytochrome P450 family 2 subfamily A member 7" P20853 19 40875439-40882752 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 71 "liver: 147.6" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 88.6" "Group enriched" "Detected in some" 238 "breast cancer: 9.2;liver cancer: 25.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "CAB033510, HPA046713, HPA047262" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 62: Hepatocytes - Metabolism" "CAB033510: AB_782366, HPA046713: AB_2679767, HPA047262: AB_2680005" "unprognostic (2.18e-1)" "unprognostic (3.60e-2)" "unprognostic (2.65e-3)" "unprognostic (8.89e-2)" "unprognostic (1.39e-2)" "unprognostic (3.95e-1)" "unprognostic (9.21e-2)" "unprognostic (8.71e-2)" "unprognostic (3.99e-2)" "unprognostic (1.06e-2)" CYP2B6 "CPB6, CYP2B, CYPIIB6" ENSG00000197408 "Cytochrome P450 family 2 subfamily B member 6" P20813 19 40991282-41018398 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 570.5" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 262.5" "Cancer enhanced" "Detected in many" "liver cancer: 28.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 11.2;liver cancer: 18.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "CAB033866, HPA048124, HPA062973" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB033866: AB_2292644, HPA048124: AB_2680274, HPA062973: AB_2684914" "unprognostic (1.86e-1)" "unprognostic (1.23e-2)" "unprognostic (1.13e-2)" "unprognostic (6.13e-2)" "unprognostic (4.59e-2)" "unprognostic (4.63e-2)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (5.78e-2)" "unprognostic (1.04e-3)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (5.44e-1)" CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 99.8;liver: 191.1;stomach 1: 65.5" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 61.9;Hepatocytes: 109.4;Proximal enterocytes: 54.2;Squamous epithelial cells: 27.9;Suprabasal keratinocytes: 62.5" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 13.3;liver cancer: 4.0" "Colon - Colon enterocytes, Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 59: Suprabasal keratinocytes - Cornification" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 184.6" "Group enriched" "Detected in some" 4 "Hepatocytes: 54.1;Proximal enterocytes: 21.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 83: Liver - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" Vesicles "HPA015066: AB_1847433, HPA074424: " "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" CYP2C8 CPC8 ENSG00000138115 "Cytochrome P450 family 2 subfamily C member 8" P10632 10 95036772-95069497 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 357 "liver: 2088.7" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 1569.4" "Cancer enriched" "Detected in some" 82 "liver cancer: 102.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "HPA013547, HPA013970, HPA015066, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Hepatocytes - Metabolism" 1 Vesicles "Plasma membrane" "HPA013547: AB_1847435, HPA013970: AB_1847434, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-2)" "unprognostic (1.80e-3)" "unprognostic (4.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "prognostic favorable (9.82e-4)" "unprognostic (2.85e-1)" "unprognostic (1.44e-3)" "unprognostic (2.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.39e-1)" "unprognostic (4.05e-4)" CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 1667.6" "Cell type enriched" "Detected in some" 32 "Hepatocytes: 1605.5" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.6;liver cancer: 1.4;prostate cancer: 1.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favorable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 307 "liver: 10050.5" "Cell type enriched" "Detected in many" 31 "Hepatocytes: 6424.4" "Cancer enriched" "Detected in some" 278 "liver cancer: 265.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.3" "Group enriched" "Detected in many" 16 "dendritic cells: 6.3;T-cells: 2.5" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" "Intracellular and membrane" Enzyme NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 31: Liver - Plasma proteins" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 43: Hepatocytes - Metabolism" "Endoplasmic reticulum, Mitochondria" "HPA009128: AB_1078613, HPA029564: AB_10602213" "unprognostic (6.32e-2)" "unprognostic (1.51e-2)" "unprognostic (3.83e-5)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-3)" "unprognostic (6.36e-3)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "unprognostic (1.70e-4)" "unprognostic (1.72e-1)" "unprognostic (8.36e-2)" "unprognostic (3.78e-1)" "unprognostic (9.59e-2)" CYP2F1 CYP2F ENSG00000197446 "Cytochrome P450 family 2 subfamily F member 1" P24903 19 41114432-41128381 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 1.3;salivary gland: 1.0;testis: 2.0" "Group enriched" "Detected in some" 8 "Club cells: 97.7;Ionocytes: 76.2" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 21: Testis - Unknown function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "unprognostic (2.04e-1)" "unprognostic (8.79e-2)" "unprognostic (4.63e-1)" "unprognostic (4.60e-2)" "unprognostic (2.54e-1)" "unprognostic (7.29e-3)" "unprognostic (6.23e-3)" "unprognostic (2.87e-2)" "unprognostic (3.91e-2)" "unprognostic (1.58e-6)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (9.90e-2)" "unprognostic (1.50e-1)" CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 86.5;intestine: 81.0;liver: 141.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 109.3;Cytotrophoblasts: 115.0;Oligodendrocytes: 63.7;Proximal enterocytes: 116.3;Syncytiotrophoblasts: 252.2" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.3" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" Enzyme NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Cytotrophoblasts - Mitochondria" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" CYP2R1 ENSG00000186104 "Cytochrome P450 family 2 subfamily R member 1" Q6VVX0 11 14877440-14892231 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Early spermatids: 190.6;Late spermatids: 115.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042949 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 13: Skin - Cornification" "Cluster 35: Non-specific - DNA binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 11: Late spermatids - Unknown function" "HPA042949: AB_2678237" "unprognostic (1.62e-2)" "unprognostic (1.82e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-3)" "unprognostic (2.67e-1)" "unprognostic (2.19e-1)" "unprognostic (3.23e-2)" "unprognostic (7.73e-2)" "unprognostic (1.70e-1)" "unprognostic (3.90e-2)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.01e-1)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "unprognostic (1.44e-2)" CYP2W1 "FLJ20359, MGC34287" ENSG00000073067 "Cytochrome P450 family 2 subfamily W member 1" Q8TAV3 7 983181-989640 "Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 18.5;intestine: 6.0;skin 1: 10.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 40.1;Fibroblasts: 6.3;Intestinal goblet cells: 11.3;Muller glia cells: 7.6;Undifferentiated cells: 19.2" "Group enriched" "Detected in many" 5 "colorectal cancer: 25.3;stomach cancer: 15.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "colorectal cancer: 10.7;Gastric cancer: 11.1" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Enzyme NA NA "Cluster 13: Skin - Cornification" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 50: Connective tissue cells - ECM organization" "unprognostic (7.09e-3)" "unprognostic (1.94e-2)" "unprognostic (2.75e-2)" "unprognostic (1.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.22e-1)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (6.26e-2)" "unprognostic (2.72e-5)" "unprognostic (7.52e-2)" "unprognostic (1.34e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.85e-4)" CYP46A1 CYP46 ENSG00000036530 "Cytochrome P450 family 46 subfamily A member 1" Q9Y6A2 14 99684298-99727301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 166.1" "Cell type enhanced" "Detected in many" "Astrocytes: 55.1;Cone photoreceptor cells: 39.1;dendritic cells: 28.2;Excitatory neurons: 51.2;Inhibitory neurons: 39.9;Rod photoreceptor cells: 31.7" "Cancer enriched" "Detected in single" 5 "glioma: 1.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "plasmacytoid DC: 3.4" "Lineage enriched" "Detected in single" 23 "dendritic cells: 3.4" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Astrocytes - Unknown function" "unprognostic (2.16e-1)" "unprognostic (4.30e-1)" "unprognostic (2.50e-5)" "unprognostic (9.48e-5)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (3.45e-2)" "unprognostic (1.06e-1)" "unprognostic (5.37e-2)" "unprognostic (4.01e-2)" "unprognostic (1.32e-5)" "unprognostic (5.21e-2)" "unprognostic (2.44e-4)" "unprognostic (5.97e-4)" "unprognostic (1.59e-1)" "unprognostic (1.15e-2)" "unprognostic (3.88e-3)" CYP4F11 ENSG00000171903 "Cytochrome P450 family 4 subfamily F member 11" Q9HBI6 19 15912367-15934867 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.1;liver: 70.5" "Cell type enhanced" "Detected in many" "Ductal cells: 15.0;Hepatocytes: 56.3;Proximal enterocytes: 13.5" "Cancer enhanced" "Detected in many" "liver cancer: 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 217.7" "Liver - Hepatocytes" "HPA017265, CAB033648, HPA058960" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 1 "CAB033648: AB_2088410, HPA017265: AB_1847451, HPA058960: AB_2683862" "prognostic favorable (4.05e-4)" "unprognostic (4.12e-2)" "unprognostic (1.79e-1)" "unprognostic (5.99e-2)" "unprognostic (5.92e-3)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (2.33e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (9.28e-4)" "unprognostic (4.44e-2)" "unprognostic (9.50e-3)" "unprognostic (2.14e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-2)" "unprognostic (4.64e-2)" CYP4F2 ENSG00000186115 "Cytochrome P450 family 4 subfamily F member 2" P78329 19 15878023-15898077 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 78.0;kidney: 39.4;liver: 161.6" "Group enriched" "Detected in some" 9 "Hepatocytes: 113.5;Proximal enterocytes: 202.2" "Cancer enriched" "Detected in some" 9 "liver cancer: 29.6" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 19 "basophil: 8.1" "Lineage enriched" "Detected in single" 81 "granulocytes: 8.1" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.8;Gastric cancer: 1.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "HPA014048, HPA017265, HPA058960" Supported "Intracellular and membrane" Enzyme NA NA "Cluster 41: Basophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 33 "HPA014048: AB_1847452, HPA017265: AB_1847451, HPA058960: AB_2683862" "unprognostic (7.46e-3)" "unprognostic (3.58e-1)" "unprognostic (3.01e-1)" "unprognostic (9.39e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-2)" "unprognostic (4.55e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (9.82e-2)" "unprognostic (2.92e-1)" "unprognostic (8.69e-4)" "unprognostic (3.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.79e-3)" CYTL1 "C17, C4orf4" ENSG00000170891 "Cytokine like 1" Q9NRR1 4 5014586-5019458 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.4" "Cell type enhanced" "Detected in some" "Adipocytes: 16.3;Endothelial cells: 33.1;Erythroid cells: 91.1;Hofbauer cells: 13.3;Lymphatic endothelial cells: 24.9;Microglial cells: 22.4" "Group enriched" "Detected in many" 5 "glioma: 21.0;melanoma: 20.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "NK-cell: 27.1" "Lineage enriched" "Detected in many" 10 "NK-cells: 27.1" "Cancer enhanced" "Detected in many" "Leukemia: 57.1;Sarcoma: 45.1;thyroid cancer: 41.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067201 Supported "Nuclear membrane,Endoplasmic reticulum" "Secreted in other tissues" "No annotated function" NA NA 270000 "Cluster 15: NK-cells - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Nuclear membrane, Endoplasmic reticulum" "HPA067201: AB_2732760" "unprognostic (2.35e-2)" "unprognostic (9.01e-3)" "unprognostic (3.56e-1)" "unprognostic (3.76e-2)" "unprognostic (1.14e-1)" "unprognostic (2.71e-1)" "unprognostic (2.09e-2)" "unprognostic (1.44e-1)" "unprognostic (7.10e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (7.43e-4)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.18e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (1.25e-4)" D2HGDH "D2HGD, FLJ42195, MGC25181" ENSG00000180902 "D-2-hydroxyglutarate dehydrogenase" Q8N465 2 241734602-241768816 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5" "Group enriched" "Detected in many" 4 "B-cells: 2.5;T-cells: 1.0" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056216, HPA060548" Uncertain Supported Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Unknown function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 16: Intestinal goblet cells - Mucin production" Mitochondria "HPA056216: AB_2683070, HPA060548: AB_2732650" "unprognostic (2.85e-1)" "unprognostic (3.35e-2)" "unprognostic (6.98e-3)" "unprognostic (7.88e-2)" "unprognostic (2.42e-1)" "prognostic favorable (9.11e-4)" "unprognostic (2.49e-3)" "unprognostic (1.67e-2)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (7.82e-3)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (9.60e-2)" "unprognostic (3.05e-2)" DAG1 "156DAG, A3a, AGRNR, DAG" ENSG00000173402 "Dystroglycan 1" Q14118 3 49468713-49535618 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 118.4;Extravillous trophoblasts: 126.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001960, CAB016353, HPA070563" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA 84000000 "Cluster 29: Non-specific - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" "Vesicles, Plasma membrane" Nucleoplasm "CAB001960: , CAB016353: AB_627292, HPA070563: " "unprognostic (1.58e-1)" "unprognostic (5.14e-1)" "unprognostic (6.71e-3)" "unprognostic (3.32e-1)" "unprognostic (7.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.67e-1)" "unprognostic (3.27e-2)" "unprognostic (8.18e-2)" "unprognostic (3.91e-2)" "unprognostic (5.70e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.59e-4)" "unprognostic (9.22e-2)" "unprognostic (1.99e-2)" "unprognostic (7.43e-2)" "unprognostic (1.57e-2)" DAND5 "CER2, CKTSF1B3, Coco, DANTE, DTE, FLJ38607, GREM3" ENSG00000179284 "DAN domain BMP antagonist family member 5" Q8N907 19 12965159-12974760 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.8;heart muscle: 8.2" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 13.6;Granulosa cells: 17.2;Lymphatic endothelial cells: 4.7;Sertoli cells: 5.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "HPA043493, HPA049472" Uncertain Approved Mitochondria "Secreted in other tissues" "No annotated function" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 6: Non-specific - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria "HPA043493: AB_2732505, HPA049472: AB_2680781" "unprognostic (1.18e-2)" "unprognostic (4.63e-2)" "unprognostic (7.51e-2)" "unprognostic (4.63e-2)" "unprognostic (3.82e-2)" "unprognostic (8.71e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-1)" "unprognostic (5.95e-3)" "unprognostic (7.27e-3)" "unprognostic (8.17e-2)" "unprognostic (2.15e-1)" "unprognostic (2.48e-10)" "unprognostic (4.43e-1)" "unprognostic (2.48e-2)" "unprognostic (6.77e-2)" "unprognostic (1.37e-1)" DAO "DAAO, DAMOX" ENSG00000110887 "D-amino acid oxidase" P14920 12 108858932-108901043 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 48.0;kidney: 86.9;liver: 145.1" "Group enriched" "Detected in some" 11 "Hepatocytes: 56.4;Proximal tubular cells: 69.1" "Cancer enriched" "Detected in some" 9 "liver cancer: 13.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Group enriched" "Detected in some" 10 "cerebellum: 66.4;pons and medulla: 20.2" "Low region specificity" "Detected in many" "HPA038653, HPA038654" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 "HPA038653: AB_10673016, HPA038654: AB_10673285" "unprognostic (1.50e-1)" "unprognostic (5.61e-2)" "unprognostic (1.43e-1)" "unprognostic (2.91e-1)" "unprognostic (2.18e-1)" "unprognostic (2.99e-2)" "unprognostic (2.31e-3)" "unprognostic (8.02e-2)" "unprognostic (2.88e-2)" "unprognostic (9.59e-2)" "unprognostic (9.07e-2)" "unprognostic (7.13e-2)" "prognostic favorable (4.11e-4)" "unprognostic (3.44e-3)" "unprognostic (8.96e-2)" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" DBH DBM ENSG00000123454 "Dopamine beta-hydroxylase" P09172 9 133636363-133659329 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "adrenal gland: 264.4" "Cell type enriched" "Detected in single" 63 "Oocytes: 58.8" "Cancer enhanced" "Detected in some" "liver cancer: 1.7" "Region enriched" "Detected in many" 22 "pons: 513.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 24 "Neuroblastoma: 209.4" "Region enriched" "Detected in some" 6 "pons and medulla: 22.1" "Region enriched" "Detected in single" 26 "pons: 22.1" "HPA002130, HPA005960, HPA070789" Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme NA NA 1600000000 "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 44: Oocytes - Unknown function" 17 Vesicles "Endoplasmic reticulum" "HPA002130: AB_2666554, HPA005960: AB_1078628, HPA070789: AB_2686312" "unprognostic (1.93e-3)" "unprognostic (7.52e-3)" "unprognostic (8.53e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-3)" "unprognostic (3.38e-3)" "unprognostic (3.39e-3)" "unprognostic (3.97e-2)" "unprognostic (1.71e-1)" "unprognostic (8.99e-2)" "unprognostic (5.80e-2)" "unprognostic (7.69e-2)" "unprognostic (2.81e-7)" "unprognostic (9.31e-2)" "unprognostic (6.77e-2)" "unprognostic (1.49e-2)" "unprognostic (5.06e-3)" DCD "AIDD, DCD-1, DSEP, HCAP, PIF" ENSG00000161634 Dermcidin P81605 12 54644589-54648493 "Plasma proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 2396.9" "Cell type enriched" "Detected in some" 26 "Melanocytes: 5710.1" "Cancer enriched" "Detected in some" 9 "breast cancer: 91.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Bone cancer: 1.0;breast cancer: 3.9" "Skin - Eccrine sweat gland cells" HPA063967 Enhanced "Secreted in other tissues" Enzyme NA NA 410000000 "Cluster 15: NK-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 2 "HPA063967: AB_2685163" "unprognostic (3.55e-2)" "unprognostic (1.61e-1)" DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 3461.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1244.1;Fibroblasts: 6900.8;Leydig cells: 6252.9;Ovarian stromal cells: 2294.9;Peritubular cells: 1873.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 724.2" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 718.9" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 1900000 "Cluster 46: Basophils - Proteolysis" "Cluster 62: Connective tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" DDIAS "C11orf82, FLJ25416, FLJ38838, noxin" ENSG00000165490 "DNA damage induced apoptosis suppressor" Q8IXT1 11 82899975-82958277 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.7;testis: 10.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 6.9;Plasma cells: 7.7;Spermatocytes: 12.3;Spermatogonia: 15.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038540, HPA038541" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 52: Non-specific - Cell proliferation" "Plasma membrane, Cytosol" "HPA038540: AB_10672648, HPA038541: AB_2676071" "unprognostic (2.53e-1)" "unprognostic (2.27e-1)" "unprognostic (5.04e-3)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (3.86e-6)" "unprognostic (4.65e-3)" "unprognostic (1.01e-3)" "unprognostic (8.24e-3)" "unprognostic (2.04e-4)" "unprognostic (4.72e-2)" "unprognostic (1.11e-16)" "unprognostic (7.17e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-1)" "unprognostic (9.13e-2)" DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA057194" Approved Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" Receptor NA NA 4400000 "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Nucleoplasm, Cell Junctions" "CAB010162: AB_2092090, CAB025656: , HPA057194: " "unprognostic (2.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.75e-3)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (4.41e-2)" "prognostic favorable (3.31e-10)" "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (5.49e-3)" "unprognostic (4.09e-2)" DDX17 P72 ENSG00000100201 "DEAD-box helicase 17" Q92841 22 38483438-38507660 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, mRNA processing, mRNA splicing, RNA-mediated gene silencing, rRNA processing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024908, HPA063142" Supported Supported "Nuclear speckles" "Intracellular and membrane" Transcription NA NA 420000 "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Neuronal - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 66: Non-specific - Mitochondria" "Cluster 55: Non-specific - Transcription" 20 "Nuclear speckles" "CAB024908: , HPA063142: AB_2684949" "unprognostic (1.46e-2)" "unprognostic (5.99e-3)" "unprognostic (4.24e-3)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.06e-4)" "unprognostic (1.17e-1)" "unprognostic (5.51e-1)" "unprognostic (2.52e-2)" "unprognostic (2.73e-2)" "unprognostic (1.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" DDX20 "DP103, GEMIN3" ENSG00000064703 "DEAD-box helicase 20" Q9UHI6 1 111754832-111775602 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 51.3" "Group enriched" "Detected in all" 7 "Early spermatids: 706.3;Late spermatids: 762.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005516, CAB015427" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 44: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 11: Late spermatids - Unknown function" 9 "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB015427: AB_629518, HPA005516: AB_1849612" "unprognostic (3.71e-2)" "unprognostic (5.25e-2)" "prognostic favorable (9.85e-5)" "unprognostic (8.73e-2)" "unprognostic (2.51e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (6.35e-6)" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (7.46e-3)" "unprognostic (4.21e-1)" "unprognostic (5.22e-2)" "unprognostic (1.05e-3)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (4.23e-1)" "unprognostic (1.30e-2)" DEAF1 "NUDR, SPN, ZMYND5" ENSG00000177030 "DEAF1 transcription factor" O75398 11 644233-707118 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 131.8" "Cell type enhanced" "Detected in all" "Oocytes: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030302 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Breast glandular cells - Lactation" 9 Nucleoplasm "Nucleoli fibrillar center" "HPA030302: AB_2673421" "unprognostic (1.32e-2)" "unprognostic (3.32e-2)" "unprognostic (3.58e-3)" "unprognostic (5.90e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (2.42e-2)" "unprognostic (2.65e-1)" "unprognostic (2.48e-1)" "unprognostic (2.61e-3)" "unprognostic (2.43e-1)" "unprognostic (2.39e-2)" "unprognostic (2.79e-1)" "unprognostic (3.03e-1)" "unprognostic (1.20e-1)" "unprognostic (5.15e-2)" DEFA1 "DEF1, DEFA2, HNP-1, MRS" ENSG00000206047 "Defensin alpha 1" P59665 8 6977649-6980092 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense, Host-virus interaction" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 35 "bone marrow: 62254.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 21 "neutrophil: 2665.7" "Lineage enriched" "Detected in many" 21 "granulocytes: 2665.7" "Cancer enriched" "Detected in single" 60 "Leukemia: 47.0" "Lung - Neutrophil_1" "CAB032548, HPA052517" Enhanced "Secreted to blood" Defense NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 7: T-cells - T-cell receptor" 1 "CAB032548: AB_2277258, HPA052517: AB_2681860" DEFA1B ENSG00000240247 "Defensin alpha 1B" P59665 8 6996766-6999198 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense, Host-virus interaction" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.3;lung: 50.5;lymphoid tissue: 146.9" "Cell type enriched" "Detected in single" 4 "Kupffer cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Neutrophil_1" HPA052517 Supported "Secreted to blood" Defense NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Neutrophils - Degranulation" 1 "HPA052517: AB_2681860" DEFA3 "DEF3, HNP-3" ENSG00000239839 "Defensin alpha 3" P59666 8 7015869-7018297 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 63 "bone marrow: 36396.6" "Cell type enriched" "Detected in some" 5 "Kupffer cells: 52.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 20 "neutrophil: 833.8" "Lineage enriched" "Detected in many" 20 "granulocytes: 833.8" "Cancer enriched" "Detected in single" 223 "Leukemia: 22.3" "Liver - Erythroid cells, Lung - Neutrophil_1" HPA052517 Supported "Secreted to blood" Defense NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" "HPA052517: AB_2681860" "unprognostic (8.21e-2)" DEFA4 "DEF4, HP-4" ENSG00000164821 "Defensin alpha 4" P12838 8 6935820-6938306 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "bone marrow: 2664.7" "Cell type enriched" "Detected in some" 10 "Kupffer cells: 10.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "neutrophil: 13.2" "Lineage enriched" "Detected in many" 13 "granulocytes: 13.2" "Cancer enriched" "Detected in single" 291 "Leukemia: 29.1" "Liver - Erythroid cells, Lung - Neutrophil_1" HPA051266 Enhanced "Secreted to blood" Defense NA NA 98000 "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" "HPA051266: AB_2681414" DEFA5 "DEF5, HD-5" ENSG00000164816 "Defensin alpha 5" Q01523 8 7055304-7056739 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 772 "intestine: 9494.8" "Cell type enriched" "Detected in some" 19 "Undifferentiated cells: 23958.3" "Cancer enhanced" "Detected in many" "cervical cancer: 181.1;colorectal cancer: 147.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 29 "Gastric cancer: 121.3" "HPA015309, HPA015775, CAB069919" Enhanced Approved Vesicles,Midbody "Secreted to digestive system" Immunity Yes NA 110000 "Cluster 25: Small intestine - Absorption" "Cluster 32: Non-specific - Cell proliferation" "Cluster 16: Intestinal goblet cells - Mucin production" Vesicles Midbody "CAB069919: AB_905358, HPA015309: , HPA015775: AB_1847594" "prognostic favorable (9.44e-5)" "unprognostic (3.91e-2)" DEFA6 "DEF6, HD-6" ENSG00000164822 "Defensin alpha 6" Q01524 8 6924697-6926076 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 865 "intestine: 4676.4" "Cell type enriched" "Detected in some" 35 "Undifferentiated cells: 10058.3" "Group enriched" "Detected in many" 5 "cervical cancer: 21.2;colorectal cancer: 75.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.7;Gastric cancer: 12.8" HPA019462 Enhanced "Secreted to digestive system" Immunity NA NA 260000 "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 3 "HPA019462: AB_1847595" "unprognostic (7.48e-3)" "unprognostic (1.63e-1)" "unprognostic (1.34e-1)" DEFB1 "BD1, DEFB-1, DEFB101, HBD-1, HBD1, MGC51822" ENSG00000164825 "Defensin beta 1" P60022 8 6870592-6877936 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 1698.6;pancreas: 725.9;salivary gland: 1917.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 1848.7;Distal tubular cells: 12736.3;Ductal cells: 1962.9;Mucus glandular cells: 5835.8;Salivary duct cells: 3325.3" "Cancer enhanced" "Detected in many" "renal cancer: 522.9" "Group enriched" "Detected in many" 5 "amygdala: 2.9;cerebellum: 3.4;hypothalamus: 1.8;midbrain: 4.7;thalamus: 6.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 57.7;ovarian cancer: 43.5" "Kidney - Intercalated cells" "Not detected" "Not detected" "Secreted in other tissues" Defense NA NA 2500000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (2.31e-2)" "unprognostic (8.35e-3)" "unprognostic (1.24e-1)" "unprognostic (1.75e-1)" "unprognostic (1.89e-1)" "unprognostic (2.16e-3)" "unprognostic (4.41e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.77e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (5.94e-4)" "unprognostic (3.24e-1)" "prognostic favorable (1.90e-5)" "unprognostic (9.62e-2)" "unprognostic (2.86e-2)" "unprognostic (2.21e-2)" "unprognostic (1.16e-1)" DEFB103A "DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3" ENSG00000176797 "Defensin beta 103A" P81534 8 7881392-7882663 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.4;salivary gland: 3.1;vagina: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.0" "Secreted in other tissues" Defense NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" 9 DEFB103B ENSG00000177243 "Defensin beta 103B" P81534 8 7428888-7430348 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "cervix: 1.3" "Cell type enhanced" "Detected in single" "Suprabasal keratinocytes: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Defense NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 9 DEFB104A "DEFB-4, DEFB104, DEFB4" ENSG00000176782 "Defensin beta 104A" Q8WTQ1 8 7836436-7841242 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 757 "epididymis: 1270.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.9;Distal tubular cells: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA045292: AB_2679288" DEFB104B ENSG00000177023 "Defensin beta 104B" Q8WTQ1 8 7470308-7475082 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" Defense NA NA "HPA045292: AB_2679288" DEFB105A "DEFB-5, DEFB105" ENSG00000186562 "Defensin beta 105A" Q8NG35 8 7821004-7823880 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1967 "epididymis: 1205.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" DEFB105B ENSG00000186599 "Defensin beta 105B" Q8NG35 8 7487679-7489593 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4893 "epididymis: 489.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 46: Lymphoma - Humoral immune response" DEFB106A "DEFB-6, DEFB106" ENSG00000186579 "Defensin beta 106A" Q8N104 8 7825139-7829053 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17324 "epididymis: 2968.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045592 Supported "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "HPA045592: AB_2679378" DEFB106B ENSG00000187082 "Defensin beta 106B" Q8N104 8 7482504-7486400 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 390 "epididymis: 38.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045592 Supported "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "HPA045592: AB_2679378" DEFB107A "DEFB-7, DEFB107" ENSG00000186572 "Defensin beta 107A" Q8IZN7 8 7811720-7815716 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 1364 "epididymis: 136.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045626 Approved "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "HPA045626: AB_2679396" DEFB107B HsT21816 ENSG00000198129 "Defensin beta 107B" Q8IZN7 8 7495911-7509311 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5184 "epididymis: 518.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045626 Approved "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "HPA045626: AB_2679396" DEFB108B ENSG00000184276 "Defensin beta 108B" Q8NET1 11 71833200-71837710 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 125 "epididymis: 12.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" 3 DEFB109B DEFB109P1B ENSG00000206034 "Defensin beta 109B" Q30KR1 8 7312722-7320096 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "epididymis: 15.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.1;Inhibitory neurons: 1.5;Oligodendrocyte precursor cells: 3.3;Oligodendrocytes: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" DEFB110 "DEFB-10, DEFB-11, DEFB111" ENSG00000203970 "Defensin beta 110" Q30KQ9 6 50009138-50021994 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 4722 "epididymis: 848.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Neurons - Neuronal signaling" DEFB113 DEFB-13 ENSG00000214642 "Defensin beta 113" Q30KQ7 6 49968677-49969625 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 462 "epididymis: 46.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" DEFB114 DEFB-14 ENSG00000177684 "Defensin beta 114" Q30KQ6 6 49960249-49964164 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 515 "epididymis: 51.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" DEFB115 DEFB-15 ENSG00000215547 "Defensin beta 115" Q30KQ5 20 31257664-31259632 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "epididymis: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053160 Uncertain "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 7: Liver cancer - Metabolism" 2 "HPA053160: AB_2682062" DEFB116 DEFB-16 ENSG00000215545 "Defensin beta 116" Q30KQ4 20 31303212-31308585 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047430 Uncertain "Secreted in male reproductive system" Defense NA NA "Cluster 51: Myeloma - Immunoglobulins" "HPA047430: AB_10964749" DEFB118 "C20orf63, DEFB-18, dJ1018D12.3, ESC42" ENSG00000131068 "Defensin beta 118" Q96PH6 20 31368601-31373923 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9676 "epididymis: 967.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042634 Enhanced "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" 2 "HPA042634: AB_10797505" "unprognostic (3.24e-1)" DEFB119 "DEFB-19, DEFB-20, DEFB120" ENSG00000180483 "Defensin beta 119" Q8N690 20 31377164-31390590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 1870.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.6;Early spermatids: 53.2;Late spermatids: 80.2;Rod photoreceptor cells: 118.8;Sertoli cells: 424.3" "Cancer enriched" "Detected in single" 67 "testis cancer: 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 1.9" HPA043059 Supported "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 66: Photoreceptor cells - Visual perception" "HPA043059: AB_10797025" "unprognostic (2.03e-1)" DEFB121 DEFB-21 ENSG00000204548 "Defensin beta 121" Q5J5C9 20 31404845-31412838 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11981 "epididymis: 2536.7" "Group enriched" "Detected in some" 23 "Early spermatids: 17.1;Late spermatids: 5.0;Spermatocytes: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA079460 Enhanced "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 8 "HPA079460: " DEFB123 DEFB-23 ENSG00000180424 "Defensin beta 123" Q8N688 20 31440632-31450257 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 371 "epididymis: 155.0;testis: 143.2" "Group enriched" "Detected in some" 6 "Late spermatids: 35.2;Sertoli cells: 76.2" "Cancer enriched" "Detected in single" 17 "testis cancer: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Defense NA NA "Cluster 63: Testis - Spermatid development" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Late spermatids - Spermatogenesis" "unprognostic (9.16e-2)" DEFB124 DEFB-24 ENSG00000180383 "Defensin beta 124" Q8NES8 20 31465471-31476757 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.7;testis: 6.9" "Group enriched" "Detected in some" 5 "Ciliated cells: 2.1;Endometrial stromal cells: 5.1;Sertoli cells: 5.4;Smooth muscle cells: 1.8" "Cancer enriched" "Detected in some" 4 "testis cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted in other tissues" Defense NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 69: Skin cancer - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" 2 "unprognostic (1.24e-2)" "unprognostic (9.76e-3)" "unprognostic (1.27e-1)" "unprognostic (3.23e-3)" "unprognostic (6.92e-3)" "unprognostic (3.69e-2)" "unprognostic (3.37e-2)" "unprognostic (1.78e-1)" "unprognostic (9.07e-2)" "unprognostic (4.43e-1)" "unprognostic (3.32e-7)" "unprognostic (1.56e-2)" "unprognostic (1.29e-1)" "unprognostic (4.42e-2)" "unprognostic (4.28e-1)" DEFB125 DEFB-25 ENSG00000178591 "Defensin beta 125" Q8N687 20 87250-97094 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "epididymis: 1.5;seminal vesicle: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 36: Late spermatids - Unknown function" DEFB126 "bA530N10.1, C20orf8, DEFB-26" ENSG00000125788 "Defensin beta 126" Q9BYW3 20 142590-145751 "Disease related genes, Predicted secreted proteins" Fertilization "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 300 "epididymis: 1251.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 12: Squamous epithelial cells - Keratinization" "unprognostic (1.16e-1)" "unprognostic (1.21e-1)" "unprognostic (3.16e-2)" "unprognostic (2.41e-2)" "unprognostic (2.32e-1)" "unprognostic (1.47e-1)" DEFB127 "bA530N10.2, C20orf73, DEF-27" ENSG00000088782 "Defensin beta 127" Q9H1M4 20 157454-159163 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1171 "epididymis: 1050.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 30: Granulocytes - Unknown function" 12 DEFB128 DEFB-28 ENSG00000185982 "Defensin beta 128" Q7Z7B8 20 187853-189711 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11632 "epididymis: 1163.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" 1 DEFB129 "bA530N10.3, C20orf87, DEFB-29" ENSG00000125903 "Defensin beta 129" Q9H1M3 20 227258-229886 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 591 "epididymis: 1895.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA014581 Enhanced "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 34: Testis cancer - Unknown function" 1 "HPA014581: AB_2732410" DEFB130A "DEFB-30, DEFB130, DEFB30" ENSG00000232948 "Defensin beta 130A" P0DP74 8 12310962-12318316 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 25 "epididymis: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" DEFB130B ENSG00000233050 "Defensin beta 130B" P0DP73 8 12064389-12071747 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 25 "epididymis: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" DEFB131A "DEFB-31, DEFB131" ENSG00000186146 "Defensin beta 131A" P59861 4 9444414-9450666 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "epididymis: 130.2" "Group enriched" "Detected in some" 20 "Basal prostatic cells: 15.2;Proximal enterocytes: 4.4" "Cancer enriched" "Detected in single" 18 "thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Secreted in other tissues" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "unprognostic (2.11e-1)" DEFB131B ENSG00000225805 "Defensin beta 131B" A0A096LNP1 11 71878453-71884561 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 67 "epididymis: 59.2" "Cell type enhanced" "Detected in single" "Inhibitory neurons: 1.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Neurons - Neuronal signaling" "unprognostic (5.87e-2)" "unprognostic (1.44e-1)" "unprognostic (4.78e-2)" "unprognostic (7.44e-2)" "unprognostic (3.57e-2)" "unprognostic (3.55e-2)" "unprognostic (3.11e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (7.45e-2)" "unprognostic (1.41e-1)" "unprognostic (1.43e-1)" "unprognostic (5.21e-2)" "unprognostic (3.39e-1)" "unprognostic (1.05e-2)" "unprognostic (3.62e-1)" DEFB132 "DEFB32, RP5-1103G7.6" ENSG00000186458 "Defensin beta 132" Q7Z7B7 20 257724-261096 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "epididymis: 264.7" "Group enriched" "Detected in some" 5 "Collecting duct cells: 11.7;Prostatic glandular cells: 4.1" "Group enriched" "Detected in some" 4 "liver cancer: 0.8;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 63 "prostate cancer: 6.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Prostate glandular cells" HPA046399 Approved "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "HPA046399: AB_10960992" "unprognostic (9.27e-3)" "unprognostic (1.61e-2)" "unprognostic (2.54e-2)" DEFB134 ENSG00000205882 "Defensin beta 134" Q4QY38 8 11993174-12000752 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "epididymis: 24.5" "Group enriched" "Detected in some" 23 "Early spermatids: 41.9;Late spermatids: 40.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 11: Late spermatids - Unknown function" "unprognostic (3.80e-2)" "unprognostic (2.20e-1)" DEFB135 ENSG00000205883 "Defensin beta 135" Q30KP9 8 11982256-11984590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 349 "epididymis: 55.3" "Group enriched" "Detected in some" 11 "Early spermatids: 1.8;Late spermatids: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 1.5" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 21: Early spermatids - Spermatogenesis" DEFB136 DEFB137 ENSG00000205884 "Defensin beta 136" Q30KP8 8 11973937-11974599 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "epididymis: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA068255 Enhanced "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 11: Late spermatids - Unknown function" "HPA068255: AB_2732780" DEFB4A "DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1" ENSG00000171711 "Defensin beta 4A" O15263 8 7894677-7896716 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 120.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 22.4;Basal respiratory cells: 79.4;Exocrine glandular cells: 16.8;Ionocytes: 22.5;Pancreatic endocrine cells: 22.1" "Group enriched" "Detected in many" 6 "head and neck cancer: 32.2;melanoma: 9.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "head and neck cancer: 3.7;Uterine cancer: 8.1" "Secreted in other tissues" Defense NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "unprognostic (6.96e-2)" "unprognostic (1.17e-2)" "unprognostic (2.72e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.75e-1)" DEFB4B DEFB4P ENSG00000177257 "Defensin beta 4B" O15263 8 7414855-7416863 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 11.6;lymphoid tissue: 3.3" "Cell type enhanced" "Detected in single" "Alveolar cells type 2: 1.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.3" "Secreted in other tissues" Defense NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "unprognostic (1.35e-1)" DEPP1 "C10orf10, DEPP, FIG, Fseg" ENSG00000165507 "DEPP1 autophagy regulator" Q9NTK1 10 44970981-44978809 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 860.9;breast: 674.3" "Cell type enhanced" "Detected in many" "Adipocytes: 185.2;Endothelial cells: 193.7;Ovarian stromal cells: 249.4;Syncytiotrophoblasts: 357.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Kidney cancer: 53.4" "Colon - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013687, HPA037818, HPA037819" Uncertain Supported Vesicles,Mitochondria "Intracellular and membrane" Other NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Mitochondria Vesicles "CAB013687: , HPA037818: , HPA037819: AB_2675685" "unprognostic (3.99e-2)" "unprognostic (4.69e-2)" "unprognostic (5.57e-2)" "unprognostic (3.55e-1)" "unprognostic (1.88e-2)" "unprognostic (5.66e-3)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (4.25e-1)" "unprognostic (5.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.89e-2)" "prognostic unfavorable (2.29e-6)" "unprognostic (2.30e-3)" "unprognostic (2.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.74e-1)" DHH "HHG-3, MGC35145" ENSG00000139549 "Desert hedgehog signaling molecule" O43323 12 49086656-49094801 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 16.2" "Group enriched" "Detected in some" 5 "Granulosa cells: 32.1;Schwann cells: 23.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "spinal cord: 10.9" "Secreted in male reproductive system" "Developmental protein" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "unprognostic (7.56e-2)" "unprognostic (2.05e-3)" "unprognostic (1.14e-1)" "unprognostic (2.93e-3)" "unprognostic (2.36e-4)" "unprognostic (1.29e-1)" "unprognostic (7.22e-3)" "unprognostic (8.21e-2)" "unprognostic (5.92e-2)" "unprognostic (1.22e-1)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (8.00e-2)" "unprognostic (1.00e-1)" "unprognostic (6.97e-2)" DHRS11 "MGC4172, SDR24C1" ENSG00000278535 "Dehydrogenase/reductase 11" Q6UWP2 17 36591879-36600804 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "intestine: 209.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 214.1;Distal enterocytes: 315.6;Paneth cells: 116.2;Proximal enterocytes: 533.9;Undifferentiated cells: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041226, HPA048236, HPA053623" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" Enzyme NA NA 42000 "Cluster 25: Small intestine - Absorption" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" Cytosol "Golgi apparatus" "HPA041226: AB_2677372, HPA048236: AB_2680322, HPA053623: AB_2682209" "unprognostic (2.00e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.80e-2)" "unprognostic (3.67e-1)" "unprognostic (5.94e-2)" "unprognostic (1.33e-2)" "unprognostic (4.11e-2)" "prognostic favorable (3.24e-4)" "unprognostic (1.45e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" DHRS13 "MGC23280, SDR7C5" ENSG00000167536 "Dehydrogenase/reductase 13" Q6UX07 17 28897781-28903079 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.1;Erythroid cells: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 55.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 55.5" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022991 Uncertain Approved Vesicles "Secreted - unknown location" Enzyme NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 1: Erythroid cells - Oxygen transport" Vesicles "HPA022991: AB_1853865" "unprognostic (8.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.35e-1)" "unprognostic (1.21e-2)" "unprognostic (6.37e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (2.38e-1)" "unprognostic (4.74e-2)" "unprognostic (5.65e-2)" "unprognostic (1.20e-2)" "unprognostic (7.57e-2)" "unprognostic (1.73e-2)" "unprognostic (3.72e-2)" "unprognostic (2.63e-1)" "unprognostic (7.22e-3)" "unprognostic (2.55e-1)" DHRS4L2 SDR25C3 ENSG00000187630 "Dehydrogenase/reductase 4 like 2" Q6PKH6 14 23969874-24006408 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 102.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 203.7;Proximal enterocytes: 335.6;Proximal tubular cells: 460.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Secreted - unknown location" Enzyme NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (1.41e-2)" "unprognostic (2.83e-3)" "unprognostic (1.25e-1)" "unprognostic (2.68e-2)" "unprognostic (1.47e-1)" "unprognostic (2.53e-1)" "unprognostic (6.02e-2)" "unprognostic (3.97e-3)" "unprognostic (7.34e-2)" "prognostic favorable (3.21e-4)" "unprognostic (1.57e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-3)" "unprognostic (6.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (3.65e-2)" DHRS7C SDR32C2 ENSG00000184544 "Dehydrogenase/reductase 7C" A6NNS2 17 9771434-9791592 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 66 "heart muscle: 120.8;skeletal muscle: 297.2;tongue: 352.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 79.4;Early spermatids: 7.0;Late spermatids: 15.7;Skeletal myocytes: 22.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "thalamus: 1.7" "Secreted in other tissues" Enzyme NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 11: Neuronal - Sensory perception" "Cluster 68: Cardiomyocytes - Muscle contraction" "unprognostic (6.83e-2)" DHRS9 "3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4" ENSG00000073737 "Dehydrogenase/reductase 9" Q9BPW9 2 169064789-169096167 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 52.1;intestine: 68.1" "Cell type enhanced" "Detected in many" "Club cells: 153.0;Distal enterocytes: 194.3;Early spermatids: 184.0;Ionocytes: 253.3;Syncytiotrophoblasts: 443.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 259.3;eosinophil: 99.5;neutrophil: 77.6" "Lineage enriched" "Detected in many" 10 "granulocytes: 259.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 144.7;pancreatic cancer: 82.9" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036491, HPA036667" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA036491: AB_10673498, HPA036667: AB_10670237" "unprognostic (1.15e-1)" "unprognostic (3.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (4.80e-2)" "unprognostic (2.35e-1)" "unprognostic (3.24e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (3.62e-4)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.72e-1)" "unprognostic (3.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-1)" DHRSX "DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6" ENSG00000169084 "Dehydrogenase/reductase X-linked" Q8N5I4 X 2219506-2502805 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "HPA003035, HPA075955" Approved Uncertain "Mitotic spindle,Cytosol" "Secreted to blood" Enzyme Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 46: Brainstem - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 14 Cytosol "Mitotic spindle" "HPA003035: AB_1080631, HPA075955: " "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-2)" "unprognostic (4.65e-3)" "unprognostic (8.87e-2)" "unprognostic (1.78e-1)" "unprognostic (1.29e-1)" "unprognostic (4.59e-3)" "unprognostic (1.08e-1)" "unprognostic (1.21e-1)" "unprognostic (1.08e-2)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (1.57e-1)" "unprognostic (2.11e-1)" "unprognostic (3.69e-2)" DHX29 DDX29 ENSG00000067248 "DExH-box helicase 29" Q7Z478 5 55256055-55307694 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Helicase, Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038317, HPA038318" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Basal prostatic cells - Lipid metabolism" Cytosol "HPA038317: AB_10673169, HPA038318: AB_10672589" "unprognostic (3.43e-2)" "unprognostic (5.09e-1)" "unprognostic (2.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (2.37e-3)" "unprognostic (1.72e-1)" "unprognostic (6.66e-2)" "unprognostic (1.76e-2)" "unprognostic (3.79e-2)" "unprognostic (1.30e-1)" "unprognostic (4.57e-3)" "unprognostic (4.01e-1)" "unprognostic (3.85e-1)" "unprognostic (4.78e-3)" "unprognostic (9.40e-2)" DHX8 "DDX8, Dhr2, HRH1, PRP22, PRPF22" ENSG00000067596 "DEAH-box helicase 8" Q14562 17 43483865-43610338 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049285 Approved Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Enzyme NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Non-specific - Transcription" 5 Nucleoplasm "Nuclear bodies" "HPA049285: AB_2680698" "unprognostic (2.99e-1)" "unprognostic (4.42e-2)" "unprognostic (5.64e-2)" "unprognostic (9.02e-2)" "unprognostic (1.25e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-3)" "unprognostic (9.43e-2)" "unprognostic (2.58e-1)" "unprognostic (3.40e-2)" "unprognostic (2.26e-2)" "unprognostic (2.47e-1)" "unprognostic (1.50e-1)" "unprognostic (4.04e-1)" "unprognostic (5.08e-3)" "unprognostic (2.60e-1)" "unprognostic (6.28e-2)" DIPK2A "C3orf58, DIA1, HASF, MGC33365" ENSG00000181744 "Divergent protein kinase domain 2A" Q8NDZ4 3 143971823-144048719 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048992 Approved "Secreted in other tissues" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 50: Connective tissue cells - ECM organization" "HPA048992: AB_2680591" "unprognostic (5.96e-2)" "unprognostic (8.54e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-1)" "unprognostic (2.43e-1)" "unprognostic (2.85e-2)" "unprognostic (3.74e-2)" "unprognostic (2.31e-2)" "unprognostic (1.52e-1)" "unprognostic (1.54e-1)" "unprognostic (3.44e-1)" "unprognostic (3.98e-1)" "prognostic unfavorable (2.92e-7)" "unprognostic (4.82e-3)" "unprognostic (2.87e-1)" "unprognostic (1.70e-1)" "unprognostic (1.50e-2)" DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 171.1;Endothelial cells: 140.5;Lymphatic endothelial cells: 151.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" "No annotated function" NA NA 940000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" DKK1 "DKK-1, SK" ENSG00000107984 "Dickkopf WNT signaling pathway inhibitor 1" O94907 10 52314281-52318042 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 32.8;placenta: 47.2" "Cell type enriched" "Detected in many" 4 "Endometrial stromal cells: 350.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" 3 "unprognostic (5.65e-2)" "unprognostic (4.21e-2)" "unprognostic (7.09e-2)" "unprognostic (7.99e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.35e-8)" "unprognostic (7.93e-2)" "prognostic unfavorable (7.80e-6)" "unprognostic (1.54e-1)" "unprognostic (6.87e-2)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.81e-1)" "unprognostic (1.68e-1)" "unprognostic (7.47e-3)" "unprognostic (4.05e-1)" "unprognostic (1.19e-1)" "unprognostic (2.06e-2)" DKK2 ENSG00000155011 "Dickkopf WNT signaling pathway inhibitor 2" Q9UBU2 4 106921802-107283806 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 14.6" "Cell type enhanced" "Detected in some" "Endothelial cells: 5.7;Fibroblasts: 19.1;Hofbauer cells: 14.8;Inhibitory neurons: 30.9;Langerhans cells: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 35.1;Neuroblastoma: 19.4;Rhabdoid: 47.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cerebral cortex: 2.1;midbrain: 6.6;pons: 8.2;thalamus: 7.6" "CAB009727, HPA052611" Uncertain Supported "Golgi apparatus" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Golgi apparatus" "CAB009727: AB_2091492, HPA052611: AB_2732576" "unprognostic (3.14e-3)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (3.21e-2)" "unprognostic (9.75e-2)" "unprognostic (3.68e-1)" "unprognostic (1.04e-3)" "unprognostic (2.47e-2)" "unprognostic (5.11e-1)" "unprognostic (5.21e-2)" "unprognostic (3.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.32e-1)" "unprognostic (1.42e-1)" "unprognostic (6.86e-2)" "unprognostic (3.22e-1)" "unprognostic (4.58e-2)" DKK3 "CRRL, REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 1277.9" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 879.7;Muller glia cells: 1813.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 7.1;memory CD8 T-cell: 4.4" "Lineage enriched" "Detected in single" 72 "T-cells: 7.1" "Cancer enhanced" "Detected in many" "Brain cancer: 311.7" "Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" "Developmental protein" No No 18000000 "Cluster 30: Heart muscle - Heart development" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 10: Muller glia cells - Visual perception" 2 Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" DKK4 ENSG00000104371 "Dickkopf WNT signaling pathway inhibitor 4" Q9UBT3 8 42374063-42377229 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.8;intestine: 2.3" "Cell type enhanced" "Detected in some" "dendritic cells: 1.6;Early spermatids: 2.6;Gastric mucus-secreting cells: 1.8;Spermatocytes: 1.6;Suprabasal keratinocytes: 1.9" "Cancer enriched" "Detected in many" 20 "endometrial cancer: 174.4" "Region enhanced" "Detected in many" "cerebellum: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 28 "breast cancer: 169.4" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA052916 Uncertain "Secreted in other tissues" "Developmental protein" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 70: DU4475 - Unknown function" "Cluster 45: Non-specific - Mixed function" 4 "HPA052916: AB_2681987" "unprognostic (1.64e-1)" "unprognostic (5.84e-2)" "unprognostic (1.97e-1)" "unprognostic (5.37e-3)" "unprognostic (3.23e-1)" "unprognostic (2.91e-2)" "unprognostic (2.13e-2)" "unprognostic (1.99e-1)" "unprognostic (6.80e-2)" "unprognostic (2.71e-2)" "unprognostic (1.63e-2)" "unprognostic (6.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (8.11e-2)" DKKL1 "CT34, SGY-1" ENSG00000104901 "Dickkopf like acrosomal protein 1" Q9UK85 19 49361783-49375116 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 277 "testis: 335.2" "Group enriched" "Detected in some" 5 "Early spermatids: 2060.7;Late spermatids: 2493.1" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 17 "B-cells: 1.7" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025410, HPA047194" Enhanced Approved Vesicles "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 5: Rhabdoid - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" Vesicles "CAB025410: , HPA047194: AB_2679979" "unprognostic (1.64e-1)" "unprognostic (5.30e-1)" "unprognostic (5.39e-4)" "unprognostic (1.85e-4)" "unprognostic (3.79e-2)" "unprognostic (4.30e-2)" "unprognostic (5.52e-4)" "unprognostic (1.00e-1)" "unprognostic (6.76e-2)" "unprognostic (4.08e-1)" "unprognostic (1.90e-1)" "unprognostic (5.65e-2)" "unprognostic (2.56e-3)" "unprognostic (1.36e-1)" "unprognostic (1.13e-1)" "unprognostic (1.18e-1)" "unprognostic (5.57e-2)" DLG4 "PSD-95, PSD95, SAP-90, SAP90" ENSG00000132535 "Discs large MAGUK scaffold protein 4" P78352 17 7187187-7219841 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 230.5;pituitary gland: 61.1;retina: 209.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 46.3;Cone photoreceptor cells: 122.3;Rod photoreceptor cells: 79.0" "Cancer enhanced" "Detected in all" "glioma: 13.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001999, CAB002000, HPA010122, HPA071006" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 12 "CAB001999: , CAB002000: , HPA010122: AB_1855169, HPA071006: " "unprognostic (7.08e-2)" "unprognostic (1.06e-2)" "unprognostic (3.50e-3)" "unprognostic (2.48e-2)" "unprognostic (3.23e-2)" "unprognostic (1.80e-1)" "unprognostic (7.18e-3)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (2.72e-2)" "prognostic favorable (8.82e-6)" "unprognostic (3.45e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.12e-2)" "unprognostic (2.83e-2)" "unprognostic (3.68e-2)" "unprognostic (4.77e-3)" DMBT1 "Gp-340, GP340, hensin, muclin, SALSA, vomeroglandin" ENSG00000187908 "Deleted in malignant brain tumors 1" Q9UGM3 10 122560665-122643736 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Differentiation, Host-virus interaction, Protein transport, Transport" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 19 "intestine: 1601.1;salivary gland: 504.2" "Group enriched" "Detected in many" 6 "Alveolar cells type 2: 237.0;Paneth cells: 360.7;Proximal enterocytes: 161.8;Serous glandular cells: 507.9;Undifferentiated cells: 211.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 47.6;stomach cancer: 76.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 26.1" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA040778 Enhanced Approved "Centriolar satellite" "Secreted in other tissues" Transport NA NA 5200000 "Cluster 25: Small intestine - Absorption" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "Centriolar satellite" "HPA040778: AB_2677132" "unprognostic (3.32e-2)" "unprognostic (2.17e-2)" "unprognostic (3.47e-2)" "prognostic favorable (1.43e-4)" "unprognostic (8.77e-2)" "unprognostic (2.56e-2)" "unprognostic (3.70e-1)" "unprognostic (7.97e-2)" "unprognostic (1.31e-1)" "unprognostic (4.51e-1)" "unprognostic (2.22e-1)" "unprognostic (2.20e-1)" "unprognostic (1.08e-9)" "unprognostic (2.26e-1)" "unprognostic (2.92e-4)" "unprognostic (2.00e-3)" "unprognostic (2.22e-1)" DMKN ZD52F10 ENSG00000161249 Dermokine Q6E0U4 19 35497220-35513658 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "skin 1: 4645.8" "Cell type enriched" "Detected in many" 8 "Suprabasal keratinocytes: 4475.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.7" "Group enriched" "Detected in many" 5 "NK-cells: 11.7;T-cells: 6.4" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2" "Region enhanced" "Detected in all" "basal ganglia: 51.9" "Low region specificity" "Detected in some" "HPA029406, HPA071641" Enhanced Approved Nucleoplasm,Cytosol "Secreted in other tissues" "No annotated function" NA NA 47000000 "Cluster 15: NK-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 12: Squamous epithelial cells - Keratinization" 6 "Nucleoplasm, Cytosol" "HPA029406: AB_10603661, HPA071641: " "unprognostic (5.70e-2)" "unprognostic (2.36e-2)" "unprognostic (3.64e-2)" "unprognostic (1.03e-1)" "unprognostic (1.28e-2)" "unprognostic (2.48e-2)" "unprognostic (3.82e-2)" "unprognostic (3.23e-1)" "unprognostic (1.03e-1)" "unprognostic (8.82e-2)" "unprognostic (2.54e-1)" "unprognostic (9.93e-2)" "prognostic favorable (5.37e-6)" "unprognostic (3.50e-1)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" DMP1 ENSG00000152592 "Dentin matrix acidic phosphoprotein 1" Q13316 4 87650280-87664361 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "Rhabdoid: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037465 Approved "Secreted to extracellular matrix" Other NA NA 64000 "Cluster 3: Rhabdoid - Membrane components" "Cluster 18: Early spermatids - Unknown function" "HPA037465: AB_10672492" "unprognostic (6.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-3)" "unprognostic (1.80e-1)" "unprognostic (4.96e-3)" "unprognostic (7.73e-2)" "unprognostic (3.88e-1)" "unprognostic (1.11e-1)" "unprognostic (1.35e-2)" "unprognostic (8.50e-9)" "unprognostic (5.82e-2)" "unprognostic (1.49e-2)" "unprognostic (2.77e-1)" "unprognostic (1.74e-3)" DMRTA2 ENSG00000142700 "DMRT like family A2" Q96SC8 1 50417550-50423443 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 1.4;pituitary gland: 1.9;testis: 1.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.8;Basal squamous epithelial cells: 10.9;Early spermatids: 13.2;Ionocytes: 3.7;Squamous epithelial cells: 4.9" "Cancer enhanced" "Detected in many" "glioma: 5.3" "Region enhanced" "Detected in many" "white matter: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 5.2;Sarcoma: 5.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA043098, HPA062958" Uncertain Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Other NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 18: Early spermatids - Unknown function" Mitochondria Nucleoplasm "HPA043098: AB_10796684, HPA062958: AB_2684911" "unprognostic (1.60e-1)" "unprognostic (4.56e-3)" "unprognostic (2.62e-1)" "unprognostic (3.07e-1)" "unprognostic (3.03e-2)" "unprognostic (2.75e-2)" "unprognostic (1.15e-2)" "unprognostic (3.29e-1)" "unprognostic (6.89e-2)" "unprognostic (4.79e-1)" "unprognostic (7.47e-2)" "unprognostic (1.21e-3)" "unprognostic (7.08e-3)" "unprognostic (4.16e-2)" "unprognostic (7.85e-2)" "unprognostic (2.68e-3)" DNAJB11 "EDJ, ERdj3, HEDJ" ENSG00000090520 "DnaJ heat shock protein family (Hsp40) member B11" Q9UBS4 3 186567403-186585800 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 233.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010814, HPA017051" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA 100000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 6 "Endoplasmic reticulum" "HPA010814: AB_1078691, HPA017051: AB_1847792" "unprognostic (4.29e-1)" "unprognostic (1.07e-1)" "unprognostic (2.98e-2)" "unprognostic (2.24e-2)" "unprognostic (8.53e-2)" "unprognostic (1.07e-3)" "unprognostic (3.86e-2)" "unprognostic (6.52e-2)" "unprognostic (7.95e-2)" "unprognostic (2.14e-3)" "unprognostic (2.58e-2)" "unprognostic (1.05e-3)" "prognostic unfavorable (3.44e-9)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (1.82e-1)" DNAJB9 MDG1 ENSG00000128590 "DnaJ heat shock protein family (Hsp40) member B9" Q9UBS3 7 108569867-108574850 "Predicted intracellular proteins" "Unfolded protein response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 391.4;Plasma cells: 344.2;Syncytiotrophoblasts: 738.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040967, HPA041553" Supported Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Other NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "Endoplasmic reticulum, Cytosol" "HPA040967: AB_10794430, HPA041553: AB_10794300" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (4.75e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-1)" "unprognostic (5.37e-2)" "unprognostic (5.13e-2)" "unprognostic (3.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.76e-1)" "unprognostic (1.05e-1)" "unprognostic (2.68e-3)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (8.76e-2)" DNAJC3 "ERdj6, HP58, P58, p58(IPK), P58IPK, PRKRI" ENSG00000102580 "DnaJ heat shock protein family (Hsp40) member C3" Q13217 13 95677139-95794988 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Antiviral defense, Stress response, Translation regulation, Unfolded protein response" "Chaperone, Repressor" "Deafness, Diabetes mellitus, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039336, HPA041326" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" Defense NA NA 4900000 "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "Endoplasmic reticulum" "HPA039336: AB_2676451, HPA041326: AB_2677412" "unprognostic (1.44e-2)" "unprognostic (8.08e-2)" "unprognostic (2.12e-2)" "prognostic favorable (3.47e-5)" "unprognostic (8.18e-2)" "unprognostic (5.78e-2)" "unprognostic (1.09e-1)" "unprognostic (2.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.45e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (9.69e-2)" "unprognostic (7.19e-2)" "unprognostic (3.37e-2)" "unprognostic (8.30e-3)" "unprognostic (8.18e-2)" DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 116.1;pancreas: 149.5" "Cell type enriched" "Detected in all" 12 "Proximal enterocytes: 645.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted to digestive system" Enzyme NA NA 420000 "Cluster 20: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.14e-4)" DNASE1L1 "DNAS1L1, DNASEX, DNL1L, XIB" ENSG00000013563 "Deoxyribonuclease 1 like 1" P49184 X 154401236-154412112 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 141.8" "Cell type enhanced" "Detected in many" "Kupffer cells: 38.0;monocytes: 39.9;Skeletal myocytes: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072635 Approved "Intracellular and membrane" Enzyme NA NA 96000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 36: Non-specific - mRNA processing" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 10 "HPA072635: AB_2686542" "unprognostic (5.27e-2)" "unprognostic (1.95e-1)" "unprognostic (4.57e-3)" "unprognostic (2.97e-1)" "unprognostic (1.27e-2)" "unprognostic (1.59e-3)" "unprognostic (3.82e-2)" "unprognostic (3.08e-2)" "unprognostic (2.88e-1)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (4.98e-1)" "prognostic favorable (2.19e-4)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "unprognostic (6.75e-2)" DNASE1L2 DNAS1L2 ENSG00000167968 "Deoxyribonuclease 1 like 2" Q92874 16 2235816-2238711 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 16.4;skin 1: 44.4" "Cell type enhanced" "Detected in some" "Astrocytes: 2.8;Cholangiocytes: 1.9;Enteroendocrine cells: 3.4;Excitatory neurons: 2.4;Inhibitory neurons: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA044714 Uncertain Mitochondria "Secreted in other tissues" Enzyme NA NA "Cluster 13: Skin - Cornification" "Cluster 6: Non-specific - Immune response" "Cluster 3: Rhabdoid - Membrane components" "Cluster 20: Enteroendocrine cells - Hormone signaling" Mitochondria "HPA044714: AB_10962870" "unprognostic (9.88e-2)" "unprognostic (1.11e-3)" "unprognostic (6.80e-4)" "unprognostic (4.29e-2)" "unprognostic (2.35e-1)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (2.50e-1)" "unprognostic (2.72e-1)" "unprognostic (1.86e-1)" "unprognostic (2.96e-3)" "unprognostic (2.17e-2)" "unprognostic (4.67e-4)" "unprognostic (1.40e-4)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.94e-4)" DNASE1L3 "DNAS1L3, LSD" ENSG00000163687 "Deoxyribonuclease 1 like 3" Q13609 3 58192257-58214697 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Necrosis" "Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "liver: 262.8;lymphoid tissue: 256.5" "Cell type enhanced" "Detected in many" "Adipocytes: 129.0;dendritic cells: 112.1;Endothelial cells: 169.9;Fibroblasts: 280.5;Kupffer cells: 146.0;Schwann cells: 315.5;Smooth muscle cells: 102.4;Suprabasal keratinocytes: 200.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 426.2" "Lineage enriched" "Detected in many" 20 "dendritic cells: 426.2" "Cancer enhanced" "Detected in some" "Leukemia: 3.1;lymphoma: 3.5;Rhabdoid: 4.8" "Liver - Sinusoid Endothelial cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 1.0" HPA019955 Approved "Secreted to blood" Enzyme NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "HPA019955: AB_1847805" "unprognostic (7.49e-3)" "unprognostic (3.08e-3)" "unprognostic (9.75e-3)" "unprognostic (3.92e-3)" "unprognostic (2.93e-3)" "unprognostic (1.01e-2)" "prognostic favorable (1.20e-6)" "unprognostic (4.74e-4)" "unprognostic (2.10e-1)" "unprognostic (9.71e-2)" "unprognostic (1.91e-3)" "unprognostic (6.95e-2)" "prognostic favorable (1.06e-7)" "unprognostic (7.57e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (5.64e-3)" DNASE2 "DNL, DNL2" ENSG00000105612 "Deoxyribonuclease 2, lysosomal" O00115 19 12875209-12881595 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Apoptosis "Developmental protein, Endonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 209.1;Paneth cells: 139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066185 Enhanced "Intracellular and membrane" "Developmental protein" NA NA 560000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 58: Macrophages - Innate immune response" "HPA066185: AB_2685632" "unprognostic (9.62e-2)" "unprognostic (2.19e-3)" "unprognostic (8.97e-2)" "unprognostic (7.45e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (5.42e-2)" "unprognostic (4.85e-2)" "unprognostic (1.40e-1)" "unprognostic (5.12e-2)" "unprognostic (4.37e-2)" "unprognostic (2.58e-2)" "unprognostic (4.69e-2)" "unprognostic (3.57e-1)" "unprognostic (1.98e-1)" DNASE2B DLAD ENSG00000137976 "Deoxyribonuclease 2 beta" Q8WZ79 1 84398484-84415018 "Enzymes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 25 "salivary gland: 165.3" "Cell type enriched" "Detected in some" 12 "Serous glandular cells: 162.8" "Group enriched" "Detected in some" 5 "melanoma: 2.8;prostate cancer: 9.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 8.4;prostate cancer: 4.1" "Lung - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Enzyme NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 30: White matter - Myelination" "Cluster 65: Non-specific - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" "unprognostic (2.24e-1)" "unprognostic (3.57e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (4.70e-2)" "unprognostic (3.70e-1)" "unprognostic (2.86e-1)" "unprognostic (1.62e-2)" "unprognostic (9.87e-2)" "unprognostic (7.90e-2)" "unprognostic (2.72e-1)" "unprognostic (1.15e-1)" "unprognostic (3.82e-5)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" "unprognostic (6.79e-2)" "unprognostic (3.08e-3)" DPEP1 ENSG00000015413 "Dipeptidase 1" P16444 16 89613308-89638456 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 376.5;kidney: 253.3;pancreas: 490.7" "Group enriched" "Detected in many" 6 "Peritubular cells: 1200.8;Proximal enterocytes: 4594.6" "Cancer enriched" "Detected in many" 8 "colorectal cancer: 107.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 134.1" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009426, HPA012783" Enhanced Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" Enzyme NA NA 370000 "Cluster 48: Stomach - Proteolysis" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 2 "Nucleoplasm, Cell Junctions" "HPA009426: AB_1847842, HPA012783: AB_1847843" "unprognostic (3.31e-2)" "unprognostic (3.86e-1)" "unprognostic (1.37e-1)" "unprognostic (1.95e-2)" "unprognostic (1.91e-2)" "unprognostic (4.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (3.45e-2)" "unprognostic (5.18e-1)" "unprognostic (8.68e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.84e-4)" "unprognostic (6.12e-3)" "unprognostic (1.92e-1)" "unprognostic (5.23e-2)" "unprognostic (3.93e-2)" DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992245-162074394 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 134.2;parathyroid gland: 151.0;placenta: 129.7;prostate: 103.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 135.0;Prostatic glandular cells: 195.7;Proximal enterocytes: 277.2;Serous glandular cells: 142.3;Syncytiotrophoblasts: 167.3" "Cancer enhanced" "Detected in all" "prostate cancer: 55.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 52.4" "Lineage enriched" "Detected in many" 10 "T-cells: 52.4" "Cancer enhanced" "Detected in many" "Kidney cancer: 54.4" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Fibroblast_2, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045970, HPA068778, HPA071236" Enhanced "Secreted to blood" Receptor NA NA 190000000 "Cluster 1: T-cells - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" 6 "CAB045970: AB_11140529, HPA068778: , HPA071236: " "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.98e-4)" "prognostic favorable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favorable (4.99e-4)" "unprognostic (1.21e-2)" DPP7 "DPP2, DPPII" ENSG00000176978 "Dipeptidyl peptidase 7" Q9UHL4 9 137110542-137118309 "Enzymes, Plasma proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 965.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021282, CAB025541, HPA059381" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted - unknown location" Enzyme NA NA 1600000 "Cluster 13: Non-specific - Mitochondria" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Late spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "CAB025541: , HPA021282: AB_1847673, HPA059381: AB_2683999" "unprognostic (1.15e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (6.07e-6)" "unprognostic (6.78e-3)" "unprognostic (1.25e-1)" "unprognostic (8.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.10e-2)" "unprognostic (2.28e-2)" "unprognostic (5.71e-3)" "prognostic favorable (8.31e-5)" "unprognostic (7.99e-2)" "unprognostic (1.46e-2)" "unprognostic (2.56e-2)" "unprognostic (1.72e-1)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 410.5" "Group enriched" "Detected in many" 6 "Fibroblasts: 261.4;Leydig cells: 162.3;Peritubular cells: 105.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.0;thyroid cancer: 6.0" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.4" HPA065548 Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 610000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" DRAXIN "C1orf187, FLJ34999, Neucrin" ENSG00000162490 "Dorsal inhibitory axon guidance protein" Q8NBI3 1 11691710-11725857 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.5;Langerhans cells: 2.3;NK-cells: 6.3;T-cells: 4.0" "Group enriched" "Detected in some" 6 "glioma: 5.1;testis cancer: 2.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.4" "Cancer enhanced" "Detected in some" "testis cancer: 4.2" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA014302 Uncertain "Secreted in brain" "Developmental protein" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: NK-cells - Adaptive immune response" 1 "HPA014302: AB_1853084" "unprognostic (5.28e-2)" "unprognostic (2.73e-1)" "unprognostic (6.58e-2)" "unprognostic (4.95e-2)" "unprognostic (2.51e-1)" "unprognostic (1.85e-1)" "unprognostic (1.37e-2)" "unprognostic (1.84e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-1)" "unprognostic (1.51e-2)" "unprognostic (7.47e-2)" "unprognostic (5.16e-6)" "unprognostic (4.65e-2)" "unprognostic (1.15e-1)" "unprognostic (8.52e-2)" "unprognostic (5.08e-1)" DSCAM "CHD2-42, CHD2-52" ENSG00000171587 "DS cell adhesion molecule" O60469 21 40010999-40847158 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.1;pituitary gland: 4.0;retina: 1.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 1045.7;Oligodendrocyte precursor cells: 4106.7" "Cancer enriched" "Detected in single" 14 "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Skin - Sebaceous gland cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019324, HPA057493" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "Golgi apparatus" "HPA019324: AB_2670118, HPA057493: " "unprognostic (1.47e-2)" "unprognostic (1.04e-1)" "unprognostic (7.59e-2)" "unprognostic (1.99e-2)" "unprognostic (9.98e-2)" "unprognostic (5.49e-4)" "unprognostic (1.78e-1)" "unprognostic (9.58e-2)" "unprognostic (7.95e-2)" "unprognostic (1.53e-1)" "unprognostic (8.85e-3)" "unprognostic (2.12e-2)" "unprognostic (2.00e-3)" "unprognostic (2.17e-2)" "unprognostic (2.29e-1)" "unprognostic (8.75e-2)" "unprognostic (5.46e-3)" DSE "DS-Epi1, DSEPI, SART2" ENSG00000111817 "Dermatan sulfate epimerase" Q9UL01 6 116254173-116444861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Isomerase "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 196.1;Late spermatids: 274.4;Macrophages: 135.2;Mesothelial cells: 126.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 5.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014764 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" "HPA014764: AB_1856587" "unprognostic (1.28e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (3.23e-3)" "unprognostic (1.21e-1)" "unprognostic (1.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.02e-2)" "unprognostic (7.81e-2)" "prognostic unfavorable (6.34e-4)" "unprognostic (5.11e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (6.19e-3)" "unprognostic (2.54e-2)" "unprognostic (2.06e-1)" "unprognostic (1.10e-2)" DSPP "DFNA39, DGI1, DMP3" ENSG00000152591 "Dentin sialophosphoprotein" Q9NZW4 4 87608529-87616873 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Deafness, Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 115 "Rhabdoid: 11.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036230 Uncertain "Secreted in other tissues" Other NA NA 27000 "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA036230: AB_10672239" "unprognostic (2.34e-1)" "unprognostic (1.08e-2)" "unprognostic (3.01e-1)" "unprognostic (1.27e-1)" "unprognostic (2.21e-2)" "unprognostic (1.26e-1)" "unprognostic (1.76e-1)" EBAG9 "EB9, RCAS1" ENSG00000147654 "Estrogen receptor binding site associated antigen 9" O00559 8 109539711-109570072 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021153, HPA021154, CAB072810, CAB072811, CAB072812" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" Other NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 23 "Golgi apparatus" "CAB072810: , CAB072811: , CAB072812: , HPA021153: AB_1856151, HPA021154: AB_1856152" "unprognostic (3.04e-2)" "unprognostic (9.99e-2)" "unprognostic (2.08e-1)" "unprognostic (1.99e-1)" "unprognostic (5.06e-2)" "unprognostic (8.13e-2)" "unprognostic (2.63e-1)" "unprognostic (3.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (1.04e-1)" "unprognostic (3.72e-1)" "unprognostic (9.72e-3)" "unprognostic (6.46e-2)" "unprognostic (5.16e-1)" "unprognostic (3.53e-1)" "unprognostic (3.71e-2)" EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 142.7" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 585.8;Syncytiotrophoblasts: 295.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.9;memory B-cell: 18.7;naive B-cell: 14.8;non-classical monocyte: 6.4" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.4" "Cancer enriched" "Detected in many" 4 "lymphoma: 69.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046635 Enhanced "Secreted to blood" Cytokine NA NA 203000 1400000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 472.5;esophagus: 1332.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 105.7;Fibroblasts: 113.6;Melanocytes: 91.0;Suprabasal keratinocytes: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 178.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (granular), Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" "Developmental protein" NA NA 8700000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Suprabasal keratinocytes - Cornification" 27 Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 119.8;ovary: 113.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 61.4;Hepatocytes: 46.9;Leydig cells: 121.5;Ovarian stromal cells: 58.4;Peritubular cells: 70.9;Smooth muscle cells: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.9" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Uncertain "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" "No annotated function" Yes NA 10000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" ECRG4 "augurin, C2orf40" ENSG00000119147 "ECRG4 augurin precursor" Q9H1Z8 2 106063246-106078155 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 424.3" "Cell type enhanced" "Detected in many" "Adipocytes: 278.5;Breast myoepithelial cells: 607.8;Ciliated cells: 160.3;Early spermatids: 751.8;Late spermatids: 441.6;Smooth muscle cells: 231.5" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 72.8" "Region enriched" "Detected in all" 10 "choroid plexus: 467.0" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 8.5;naive CD8 T-cell: 7.2" "Lineage enriched" "Detected in single" 83 "T-cells: 8.5" "Not detected" "Not detected" "Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008546 Uncertain "Secreted to blood" "No annotated function" NA NA 330000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 21: Early spermatids - Spermatogenesis" 2 "HPA008546: AB_2066524" "prognostic favorable (4.58e-4)" "unprognostic (3.91e-1)" "unprognostic (2.44e-2)" "unprognostic (1.34e-2)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.61e-3)" "unprognostic (6.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-3)" "unprognostic (1.36e-2)" "unprognostic (1.06e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (9.11e-3)" "unprognostic (1.30e-4)" EDA "ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED" ENSG00000158813 "Ectodysplasin A" Q92838 X 69616067-70039472 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 80.5;Oligodendrocyte precursor cells: 28.3;Oligodendrocytes: 42.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;MAIT T-cell: 1.3" "Group enriched" "Detected in many" 5 "monocytes: 1.2;T-cells: 1.3" "Cancer enhanced" "Detected in many" "prostate cancer: 6.1" "Skeletal muscle - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA037972, HPA037973" Supported "Vesicles,Lipid droplets" "Secreted - unknown location" "Developmental protein" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 76: Oligodendrocyte precursor - Unknown function" 20 Vesicles "Lipid droplets" "HPA037972: AB_2675761, HPA037973: AB_2675762" "unprognostic (3.76e-2)" "unprognostic (8.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.59e-3)" "unprognostic (7.85e-2)" "unprognostic (1.25e-4)" "unprognostic (4.33e-4)" "unprognostic (5.03e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-2)" "unprognostic (2.01e-1)" "prognostic favorable (1.04e-9)" "unprognostic (8.63e-4)" "unprognostic (7.64e-2)" "unprognostic (9.85e-2)" "unprognostic (2.79e-1)" EDDM13 ENSG00000267710 "Epididymal protein 13" A0A1B0GTR0 19 56272748-56310454 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 141 "epididymis: 96.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5.8;Lymphatic endothelial cells: 7.7;Suprabasal keratinocytes: 8.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "unprognostic (1.08e-4)" "unprognostic (1.19e-2)" "unprognostic (2.27e-1)" "unprognostic (1.40e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-1)" "unprognostic (3.22e-3)" "unprognostic (1.33e-1)" "unprognostic (5.23e-3)" "unprognostic (2.93e-2)" "unprognostic (9.16e-2)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (3.84e-2)" "unprognostic (4.20e-1)" EDDM3A "FAM12A, HE3-ALPHA" ENSG00000181562 "Epididymal protein 3A" Q14507 14 20745887-20748380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "epididymis: 620.9" "Group enriched" "Detected in some" 22 "Basal prostatic cells: 25.9;Collecting duct cells: 31.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049952 Approved "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 11: White matter - Signal transduction" "Cluster 50: Lymphoma - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" "HPA049952: AB_2680970" "unprognostic (1.42e-1)" "unprognostic (9.88e-2)" "unprognostic (8.56e-3)" "unprognostic (2.10e-1)" EDDM3B "FAM12B, HE3-BETA" ENSG00000181552 "Epididymal protein 3B" P56851 14 20768404-20770948 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 283 "epididymis: 2502.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA001323 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 50: Lymphoma - Unknown function" 17 "HPA001323: AB_1848377" "unprognostic (2.40e-2)" EDEM2 "bA4204.1, C20orf31, C20orf49, FLJ10783" ENSG00000088298 "ER degradation enhancing alpha-mannosidase like protein 2" Q9BV94 20 35115364-35147336 "Predicted intracellular proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 161.9;Plasma cells: 99.4;Syncytiotrophoblasts: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037238, HPA048353" Approved "Intracellular and membrane" Other NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 53: Non-specific - Glycosylation" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 77: Plasma cells - Protein processing" "CAB037238: AB_1840826, HPA048353: AB_2680369" "unprognostic (1.19e-1)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.05e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.31e-3)" "unprognostic (1.81e-1)" "unprognostic (2.10e-2)" "unprognostic (9.87e-2)" "unprognostic (1.46e-1)" "unprognostic (5.09e-2)" "prognostic unfavorable (4.76e-6)" "unprognostic (4.53e-2)" "unprognostic (1.31e-1)" "unprognostic (3.50e-3)" "unprognostic (2.29e-2)" EDEM3 C1orf22 ENSG00000116406 "ER degradation enhancing alpha-mannosidase like protein 3" Q9BZQ6 1 184690237-184754907 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Unfolded protein response" Hydrolase "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 76.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025754, HPA025755, HPA027297" Approved Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 16: Intestinal goblet cells - Mucin production" "Endoplasmic reticulum" "HPA025754: AB_1845638, HPA025755: AB_1845639, HPA027297: AB_2672205" "unprognostic (1.74e-1)" "unprognostic (1.64e-2)" "unprognostic (3.08e-2)" "unprognostic (2.67e-2)" "unprognostic (2.30e-1)" "unprognostic (3.10e-2)" "unprognostic (7.52e-3)" "unprognostic (1.82e-1)" "unprognostic (7.06e-2)" "unprognostic (1.66e-1)" "unprognostic (1.66e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.63e-6)" "unprognostic (4.72e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-2)" "unprognostic (2.01e-1)" EDIL3 DEL1 ENSG00000164176 "EGF like repeats and discoidin domains 3" O43854 5 83940554-84384880 "Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 187.8" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 526.8;Oligodendrocytes: 1973.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 114.3;Kidney cancer: 115.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020415, HPA022122" Approved Uncertain "Plasma membrane" "Secreted to blood" "Developmental protein" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane" "HPA020415: AB_2670434, HPA022122: " "unprognostic (9.93e-3)" "unprognostic (2.38e-1)" "unprognostic (2.71e-2)" "unprognostic (8.63e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (9.19e-2)" "unprognostic (6.64e-3)" "unprognostic (2.98e-1)" "unprognostic (1.56e-1)" "unprognostic (1.04e-1)" "unprognostic (1.03e-3)" "unprognostic (2.52e-2)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (1.28e-3)" EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 43.1" "Cell type enhanced" "Detected in many" "Adipocytes: 200.1;Ductal cells: 266.1;Endothelial cells: 208.7;Enteroendocrine cells: 233.1;Exocrine glandular cells: 204.6;Glandular and luminal cells: 311.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cancer enhanced" "Detected in many" "testis cancer: 108.1" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031976, CAB032500, CAB037291" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted to blood" Other NA Yes 9740 "Cluster 25: Non-specific - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "Nucleoli, Golgi apparatus" Nucleoplasm "CAB032500: AB_2096241, CAB037291: AB_259277, HPA031976: AB_10602489" "unprognostic (1.51e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" "unprognostic (9.72e-2)" "unprognostic (3.40e-1)" "unprognostic (1.91e-1)" "unprognostic (6.24e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (8.92e-2)" "unprognostic (4.19e-2)" "unprognostic (3.17e-1)" "unprognostic (8.02e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (3.47e-1)" EDN2 ET2 ENSG00000127129 "Endothelin 2" P20800 1 41478775-41484683 "Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 25.4;esophagus: 20.2;vagina: 31.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 143.6;Club cells: 135.7;Collecting duct cells: 72.0;Ionocytes: 104.2;Proximal enterocytes: 83.1;Secretory cells: 57.5" "Cancer enhanced" "Detected in many" "cervical cancer: 24.0" "Region enriched" "Detected in single" 7 "choroid plexus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 30.6;Uterine cancer: 24.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028459 Uncertain Approved Cytosol "Secreted to blood" Other NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" Cytosol "HPA028459: AB_10602490" "unprognostic (2.71e-2)" "unprognostic (5.64e-2)" "unprognostic (8.39e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.47e-2)" "unprognostic (3.87e-1)" "unprognostic (2.66e-2)" "unprognostic (1.04e-1)" "unprognostic (5.44e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.81e-4)" "unprognostic (5.59e-2)" "unprognostic (1.28e-2)" "unprognostic (8.47e-2)" "unprognostic (1.76e-1)" "unprognostic (6.14e-2)" "unprognostic (3.85e-1)" EDN3 ET3 ENSG00000124205 "Endothelin 3" P14138 20 59300443-59325992 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Deafness, Disease variant, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 51.7;salivary gland: 66.3;vagina: 103.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 86.4;Distal enterocytes: 72.0;Paneth cells: 69.9;Proximal enterocytes: 91.7;Squamous epithelial cells: 64.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 19.1;Uterine cancer: 25.7" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Other NA NA 30900 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 19: Astrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" "unprognostic (4.64e-3)" "unprognostic (7.87e-2)" "unprognostic (7.49e-2)" "unprognostic (2.88e-3)" "prognostic favorable (1.73e-4)" "unprognostic (1.58e-1)" "unprognostic (1.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (4.01e-2)" "unprognostic (4.08e-2)" "unprognostic (4.48e-1)" "unprognostic (6.11e-2)" "unprognostic (1.55e-1)" "unprognostic (6.40e-2)" EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 342.8;Cytotrophoblasts: 1342.6;Fibroblasts: 310.2;Lymphatic endothelial cells: 378.4;Mesothelial cells: 769.6;Syncytiotrophoblasts: 824.5" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 474.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" "Growth factor" NA NA 1900000000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 46: Brainstem - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 24: Cytotrophoblasts - Mitochondria" 27 Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" EFEMP2 "FBLN4, UPH1" ENSG00000172638 "EGF containing fibulin extracellular matrix protein 2" O95967 11 65866441-65873592 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 105.0;Leydig cells: 93.8;Muller glia cells: 82.4;Ovarian stromal cells: 104.6;Peritubular cells: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023270 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 2600000 "Cluster 21: Neutrophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 83 "HPA023270: AB_1848019" "unprognostic (3.13e-1)" "unprognostic (2.15e-3)" "unprognostic (3.23e-2)" "unprognostic (5.11e-2)" "unprognostic (8.57e-3)" "unprognostic (1.50e-1)" "unprognostic (1.67e-1)" "unprognostic (6.52e-2)" "unprognostic (1.13e-2)" "unprognostic (1.71e-1)" "unprognostic (4.89e-2)" "unprognostic (9.12e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (8.33e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.58e-2)" EFNA1 "ECKLG, EPLG1, GMAN, LERK1, TNFAIP4" ENSG00000169242 "Ephrin A1" P20827 1 155127876-155134899 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 461.3" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 1137.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 11.5;naive CD8 T-cell: 5.9" "Lineage enriched" "Detected in single" 23 "T-cells: 11.5" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Lung - Alveolar cells type 1, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069549 Approved "Secreted to blood" "Developmental protein" NA Yes 2800000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" 2 "HPA069549: " "unprognostic (5.14e-2)" "unprognostic (3.04e-3)" "unprognostic (5.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.78e-2)" "unprognostic (5.80e-3)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (2.00e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (3.58e-1)" "unprognostic (1.93e-1)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" EFNA2 "ELF-1, EPLG6, LERK6" ENSG00000099617 "Ephrin A2" O43921 19 1285873-1301431 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "gallbladder: 3.4;intestine: 12.0;liver: 12.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 21.0;Distal enterocytes: 56.7;Intestinal goblet cells: 18.0;Paneth cells: 32.4;Proximal enterocytes: 56.4;Undifferentiated cells: 19.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.5;stomach cancer: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.0" "Colon - Colon enterocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067567 Approved Mitochondria,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 5: Enterocytes - Absorption" 1 "Mitochondria, Cytosol" "HPA067567: AB_2732771" "unprognostic (1.98e-1)" "unprognostic (3.26e-1)" "unprognostic (2.87e-3)" "unprognostic (1.96e-2)" "unprognostic (4.04e-2)" "unprognostic (3.90e-1)" "unprognostic (7.19e-2)" "unprognostic (2.34e-3)" "unprognostic (3.58e-2)" "unprognostic (6.82e-2)" "unprognostic (8.48e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-3)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-4)" "unprognostic (1.94e-1)" EFNA4 "EPLG4, LERK4" ENSG00000243364 "Ephrin A4" P52798 1 155063737-155069553 "Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 29.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" CAB021350 Uncertain "Secreted to blood" "No annotated function" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 13: Skin - Cornification" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "CAB021350: " "unprognostic (4.65e-2)" "unprognostic (8.07e-2)" "unprognostic (3.43e-2)" "unprognostic (7.04e-2)" "unprognostic (7.91e-2)" "unprognostic (4.81e-1)" "prognostic unfavorable (1.00e-5)" "unprognostic (1.37e-2)" "unprognostic (3.89e-2)" "unprognostic (6.17e-2)" "unprognostic (2.87e-2)" "unprognostic (7.97e-3)" "prognostic unfavorable (3.14e-4)" "prognostic favorable (3.60e-5)" "unprognostic (3.35e-2)" "unprognostic (1.97e-1)" "unprognostic (6.29e-2)" EGFL6 MAEG ENSG00000198759 "EGF like domain multiple 6" Q8IUX8 X 13569601-13633575 "Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "placenta: 623.7" "Group enriched" "Detected in many" 4 "Oocytes: 48.5;Smooth muscle cells: 147.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 24.7" "Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001838 Enhanced "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 2 "HPA001838: AB_2666457" "unprognostic (1.66e-1)" "unprognostic (1.32e-2)" "unprognostic (9.15e-3)" "unprognostic (3.76e-3)" "unprognostic (1.77e-2)" "prognostic favorable (9.73e-4)" "unprognostic (4.13e-3)" "unprognostic (1.37e-1)" "unprognostic (5.19e-3)" "prognostic favorable (4.95e-4)" "unprognostic (2.39e-3)" "unprognostic (1.81e-1)" "unprognostic (1.14e-9)" "unprognostic (7.10e-2)" "unprognostic (3.21e-2)" "unprognostic (1.70e-1)" "unprognostic (1.82e-3)" EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 783.1;Endothelial cells: 505.6;Hofbauer cells: 261.1;Lymphatic endothelial cells: 322.0;Spermatogonia: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.6;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" EGFL8 "C6orf8, NG3" ENSG00000241404 "EGF like domain multiple 8" Q99944 6 32164595-32168281 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Schwann cells: 34.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "skin cancer: 10.1" "Colon - Enteric glia cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061173 Uncertain Approved "Nuclear speckles,Vesicles" "Secreted - unknown location" "No annotated function" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 8 Vesicles "Nuclear speckles" "HPA061173: AB_2684443" "unprognostic (7.13e-2)" "unprognostic (1.86e-1)" "unprognostic (6.79e-3)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (7.60e-4)" "unprognostic (3.42e-2)" "unprognostic (2.49e-1)" "unprognostic (6.42e-3)" "unprognostic (1.97e-1)" "unprognostic (7.60e-3)" "unprognostic (8.11e-3)" "unprognostic (1.07e-4)" "unprognostic (1.11e-1)" "unprognostic (6.79e-2)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" EGFLAM "AGRINL, AGRNL, FLJ39155, PIKA" ENSG00000164318 "EGF like, fibronectin type III and laminin G domains" Q63HQ2 5 38258409-38465480 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 116.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.4;Early spermatids: 46.5;Late spermatids: 49.7;Leydig cells: 161.0;Rod photoreceptor cells: 38.6;Sertoli cells: 38.1;Smooth muscle cells: 47.7" "Cancer enhanced" "Detected in all" "testis cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 37.6" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066577 Approved "Secreted - unknown location" "No annotated function" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA066577: " "unprognostic (2.05e-1)" "unprognostic (4.81e-2)" "unprognostic (1.01e-1)" "unprognostic (1.38e-3)" "unprognostic (1.08e-2)" "unprognostic (3.63e-3)" "unprognostic (6.31e-2)" "unprognostic (2.83e-1)" "unprognostic (2.08e-2)" "unprognostic (1.71e-3)" "unprognostic (1.12e-1)" "unprognostic (5.80e-2)" "prognostic unfavorable (4.47e-5)" "unprognostic (7.02e-6)" "unprognostic (2.60e-1)" "unprognostic (9.90e-2)" "unprognostic (1.04e-2)" EGFR "ERBB, ERBB1, ERRP" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 63.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 278.2;Salivary duct cells: 235.0;Syncytiotrophoblasts: 428.1" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534, CAB080313, CAB080314" Enhanced Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cell Junctions" "Secreted to blood" Receptor NA NA 4740000 88000000 "Cluster 58: Placenta - Pregnancy" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Fibroblasts - ECM organization" 270 "Plasma membrane, Cell Junctions" "Nucleoplasm, Nucleoli" "CAB000035: , CAB068186: AB_2665679, CAB073534: , CAB080313: , CAB080314: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" EHF "ESE3, ESEJ" ENSG00000135373 "ETS homologous factor" Q9NZC4 11 34621093-34663288 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 279.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 513.0;Basal respiratory cells: 388.6;Club cells: 409.9;Glandular and luminal cells: 405.6;Mucus glandular cells: 523.4;Salivary duct cells: 456.4;Serous glandular cells: 374.2;Squamous epithelial cells: 388.3;Suprabasal keratinocytes: 385.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "myeloid DC: 1.7" "Lineage enriched" "Detected in single" 11 "dendritic cells: 1.7" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA050923, HPA060734" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Transcription No NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" Nucleoplasm "Golgi apparatus" "HPA050923: AB_2681275, HPA060734: AB_2684351" "unprognostic (1.06e-2)" "unprognostic (1.06e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.82e-1)" "unprognostic (5.62e-2)" "unprognostic (1.22e-3)" "unprognostic (2.44e-1)" "unprognostic (2.04e-1)" "unprognostic (1.38e-1)" "unprognostic (6.79e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (1.29e-1)" "unprognostic (6.26e-2)" "unprognostic (3.47e-3)" "unprognostic (2.24e-1)" "unprognostic (2.89e-1)" "unprognostic (7.08e-2)" EHMT2 "BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a" ENSG00000204371 "Euchromatic histone lysine methyltransferase 2" Q96KQ7 6 31879759-31897698 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050550, HPA060259" Supported Supported "Nucleoplasm,Nuclear speckles" "Intracellular and membrane" Enzyme NA NA "Cluster 66: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 25 "Nucleoplasm, Nuclear speckles" "HPA050550: AB_2681170, HPA060259: AB_2684234" "unprognostic (3.11e-2)" "unprognostic (2.72e-1)" "unprognostic (4.39e-2)" "unprognostic (1.92e-2)" "unprognostic (5.44e-2)" "unprognostic (3.51e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (3.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.89e-2)" "unprognostic (1.88e-1)" "unprognostic (9.78e-3)" "unprognostic (8.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.25e-1)" "unprognostic (9.03e-2)" ELANE "ELA2, HLE, HNE, NE, PMN-E" ENSG00000197561 "Elastase, neutrophil expressed" P08246 19 851014-856247 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 92 "bone marrow: 3840.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 12.5;Kupffer cells: 9.1;Langerhans cells: 5.5;Leydig cells: 6.8;Oocytes: 19.1" "Group enriched" "Detected in some" 7 "pancreatic cancer: 3.5;stomach cancer: 3.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "classical monocyte: 4.0;neutrophil: 12.2" "Group enriched" "Detected in many" 9 "granulocytes: 12.2;monocytes: 4.0" "Cancer enriched" "Detected in some" 227 "Leukemia: 236.6" "Lung - Neutrophil_1, Skin - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015409, HPA066836, HPA073774" Enhanced "Secreted to blood" Enzyme NA NA 370000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" "CAB015409: AB_831596, HPA066836: AB_2685733, HPA073774: " "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-3)" "unprognostic (2.09e-2)" "unprognostic (1.80e-3)" "unprognostic (3.43e-2)" "unprognostic (3.92e-1)" "unprognostic (6.38e-3)" "unprognostic (5.80e-1)" "unprognostic (2.54e-2)" "unprognostic (4.06e-2)" "unprognostic (3.48e-2)" "unprognostic (1.19e-10)" "unprognostic (6.27e-3)" "unprognostic (4.00e-2)" "unprognostic (2.76e-2)" "unprognostic (4.75e-3)" ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 65.0;Fibroblasts: 141.7;Leydig cells: 107.7;Lymphatic endothelial cells: 65.5;Peritubular cells: 135.0;Skeletal myocytes: 115.1;Smooth muscle cells: 71.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Brain cancer: 62.6;Sarcoma: 187.5" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA 2900000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 4 "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" ELP5 "C17orf81, DERP6" ENSG00000170291 "Elongator acetyltransferase complex subunit 5" Q8TE02 17 7251416-7259940 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 165.0" "Group enriched" "Detected in all" 4 "Early spermatids: 445.5;Late spermatids: 708.3;Spermatocytes: 189.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023279, HPA052411" Uncertain Supported Nucleoplasm,Cytosol "Intracellular and membrane" Other NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Testis - Spermatogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 2 "Nucleoplasm, Cytosol" "HPA023279: AB_1847613, HPA052411: " "unprognostic (3.73e-2)" "unprognostic (9.21e-3)" "unprognostic (1.24e-1)" "unprognostic (2.39e-3)" "unprognostic (7.72e-2)" "unprognostic (1.22e-1)" "unprognostic (7.70e-2)" "unprognostic (1.53e-1)" "unprognostic (7.83e-3)" "unprognostic (1.60e-2)" "prognostic favorable (2.62e-4)" "unprognostic (1.36e-1)" "unprognostic (1.83e-1)" "unprognostic (8.07e-2)" "unprognostic (2.71e-1)" "unprognostic (1.62e-1)" "unprognostic (2.30e-2)" ELSPBP1 "E12, EDDM12, HE12" ENSG00000169393 "Epididymal sperm binding protein 1" Q96BH3 19 47994632-48025154 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "epididymis: 2760.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 33.8;Cone photoreceptor cells: 11.9;Early spermatids: 26.4;Late spermatids: 34.0;Muller glia cells: 14.9;Rod photoreceptor cells: 97.6" "Cancer enhanced" "Detected in single" "melanoma: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Brain cancer: 3.3" "Not detected" "Not detected" "HPA044256, HPA050341" Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 38: Non-specific - Transcription" "Cluster 66: Photoreceptor cells - Visual perception" "HPA044256: AB_2678879, HPA050341: AB_2681097" "unprognostic (1.51e-1)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" EMC10 "C19orf63, HSM1, HSS1, INM02" ENSG00000161671 "ER membrane protein complex subunit 10" Q5UCC4 19 50476400-50490871 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Angiogenesis "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 178.8" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 625.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053905, HPA062723" Approved "Secreted to blood" "Developmental protein" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 2: Skeletal myocytes - Muscle contraction" 8 "HPA053905: AB_2682303, HPA062723: " "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (9.86e-3)" "unprognostic (1.65e-1)" "unprognostic (6.94e-2)" "unprognostic (8.38e-3)" "unprognostic (3.23e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-1)" "unprognostic (2.99e-1)" "prognostic favorable (4.39e-4)" "unprognostic (5.01e-2)" "prognostic favorable (6.64e-6)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 394.2;Endothelial cells: 263.1;Lymphatic endothelial cells: 174.4;Microglial cells: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" "No annotated function" NA NA 470000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" EMID1 "EMI5, EMU1, hEmu1" ENSG00000186998 "EMI domain containing 1" Q96A84 22 29205896-29259597 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.7;lymphoid tissue: 53.4" "Cell type enhanced" "Detected in many" "Astrocytes: 87.3;Endometrial stromal cells: 22.7;Glandular and luminal cells: 19.2;granulocytes: 29.6;Oligodendrocyte precursor cells: 48.6" "Group enriched" "Detected in all" 4 "endometrial cancer: 23.1;glioma: 7.8;ovarian cancer: 10.9;thyroid cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Leukemia: 31.5" "Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000592 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 9: Endometrial stromal cells - Transcription" "HPA000592: AB_1078737" "unprognostic (2.20e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-2)" "unprognostic (7.80e-3)" "unprognostic (2.40e-2)" "unprognostic (1.42e-1)" "unprognostic (3.46e-1)" "unprognostic (6.25e-3)" "unprognostic (3.75e-2)" "unprognostic (2.33e-1)" "unprognostic (5.24e-3)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "unprognostic (3.09e-2)" "unprognostic (1.08e-1)" EMILIN1 "DKFZp586M121, EMILIN, gp115" ENSG00000138080 "Elastin microfibril interfacer 1" Q9Y6C2 2 27078615-27086403 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 57.2;Fibroblasts: 96.2;Leydig cells: 83.0;Lymphatic endothelial cells: 51.5;Ovarian stromal cells: 90.3;Peritubular cells: 162.1;Smooth muscle cells: 58.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 114.3" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002822 Supported "Secreted to extracellular matrix" "Cell adhesion" NA NA 4300000 "Cluster 13: Non-specific - Mitochondria" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 11 "HPA002822: AB_1078738" "unprognostic (3.14e-1)" "unprognostic (2.44e-2)" "unprognostic (3.92e-2)" "unprognostic (3.42e-2)" "unprognostic (3.26e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-1)" "unprognostic (2.89e-2)" "unprognostic (4.10e-3)" "unprognostic (3.07e-2)" "unprognostic (1.85e-1)" "unprognostic (7.97e-2)" "prognostic unfavorable (8.13e-9)" "unprognostic (8.96e-3)" "unprognostic (3.77e-2)" "unprognostic (1.20e-2)" "unprognostic (5.70e-3)" EMILIN2 "FLJ33200, FOAP-10" ENSG00000132205 "Elastin microfibril interfacer 2" Q9BXX0 18 2847006-2916003 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 73.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 100.7;granulocytes: 124.6;Hofbauer cells: 70.9;Langerhans cells: 118.5;Macrophages: 110.5;monocytes: 231.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.5" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 23.6" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 33.7" HPA064576 Supported "Secreted to extracellular matrix" "Cell adhesion" NA NA 840000 "Cluster 41: Basophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 29: Monocytes - Innate immune response" "HPA064576: AB_2732717" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (7.91e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-3)" "unprognostic (9.91e-3)" "prognostic unfavorable (6.30e-4)" "unprognostic (2.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.49e-1)" "unprognostic (3.15e-3)" "unprognostic (3.72e-2)" "unprognostic (2.96e-1)" EMILIN3 "C20orf130, dJ620E11.4, EMILIN5" ENSG00000183798 "Elastin microfibril interfacer 3" Q9NT22 20 41359962-41366818 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 52.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 15.9;Granulosa cells: 6.9;Microglial cells: 4.5;Oligodendrocyte precursor cells: 3.3;Peritubular cells: 4.4" "Group enriched" "Detected in many" 5 "glioma: 10.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.4" "Skin - Sebaceous gland cells, Stomach - Fibroblasts" "Region enriched" "Detected in single" 30 "cerebellum: 3.3" "Region enriched" "Detected in some" 4 "spinal cord: 5.4" "HPA044034, HPA059912, HPA078559" Enhanced Uncertain "Golgi apparatus" "Secreted to extracellular matrix" "No annotated function" NA NA 1200000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 45: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 6 "Golgi apparatus" "HPA044034: AB_2678783, HPA059912: AB_2684158, HPA078559: " "unprognostic (1.66e-4)" "unprognostic (1.85e-2)" "unprognostic (2.50e-2)" "unprognostic (2.14e-1)" "unprognostic (2.65e-1)" "unprognostic (2.15e-2)" "unprognostic (1.71e-1)" "unprognostic (7.66e-2)" "unprognostic (2.18e-3)" "unprognostic (2.57e-1)" "unprognostic (6.54e-2)" "unprognostic (7.66e-2)" "unprognostic (3.13e-7)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.97e-1)" "unprognostic (9.62e-2)" ENAM AIH2 ENSG00000132464 Enamelin Q9NRM1 4 70628744-70646824 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.3;heart muscle: 6.3;kidney: 8.6;skeletal muscle: 4.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.3;Cholangiocytes: 3.8;Collecting duct cells: 3.9;Distal tubular cells: 3.1;Late spermatids: 4.2;Proximal tubular cells: 3.6;Skeletal myocytes: 3.9" "Group enriched" "Detected in some" 5 "pancreatic cancer: 0.6;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.8;Rhabdoid: 1.1" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" Other NA NA 23000 "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 38: Proximal tubular cells - Transmembrane transport" "unprognostic (1.52e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (1.02e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (7.94e-3)" "unprognostic (4.73e-2)" "unprognostic (2.06e-1)" "unprognostic (9.06e-4)" "unprognostic (1.01e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.81e-14)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (2.12e-1)" "unprognostic (1.45e-1)" ENDOD1 KIAA0830 ENSG00000149218 "Endonuclease domain containing 1" O94919 11 95089846-95132645 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 92.9;Oligodendrocytes: 114.4;Schwann cells: 109.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008932, HPA010517" Enhanced Approved "Nuclear membrane" "Secreted - unknown location" Immunity NA NA 5200000 "Cluster 14: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 "Nuclear membrane" "HPA008932: AB_2262252, HPA010517: AB_1852351" "unprognostic (8.81e-3)" "unprognostic (1.92e-2)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (6.34e-2)" "unprognostic (2.78e-2)" "unprognostic (4.43e-2)" "unprognostic (2.23e-1)" "unprognostic (1.41e-1)" "unprognostic (3.65e-1)" "prognostic unfavorable (8.86e-4)" "unprognostic (2.84e-1)" "prognostic favorable (6.64e-7)" "unprognostic (5.92e-2)" "unprognostic (2.35e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (3.27e-4)" ENDOG ENSG00000167136 "Endonuclease G" Q14249 9 128818500-128822676 "Plasma proteins, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 130.5" "Cell type enhanced" "Detected in all" "Ciliated cells: 149.5;Late spermatids: 160.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021335, HPA021830" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium assembly" 1 "HPA021335: AB_1848151, HPA021830: AB_1848152" "unprognostic (1.35e-1)" "unprognostic (3.41e-1)" "unprognostic (4.86e-2)" "prognostic favorable (5.12e-4)" "unprognostic (2.51e-1)" "unprognostic (3.95e-1)" "unprognostic (6.56e-2)" "unprognostic (2.64e-2)" "unprognostic (4.90e-1)" "unprognostic (6.97e-2)" "unprognostic (8.35e-3)" "unprognostic (1.03e-1)" "prognostic favorable (1.06e-7)" "unprognostic (1.69e-2)" "unprognostic (1.81e-1)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" ENDOU "P11, PP11, PRSS26" ENSG00000111405 "Endonuclease, poly(U) specific" P21128 12 47709734-47725567 "Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 80.5;vagina: 30.0" "Group enriched" "Detected in some" 10 "Suprabasal keratinocytes: 93.2;Syncytiotrophoblasts: 65.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012388, HPA067448" Enhanced "Secreted in other tissues" Enzyme NA NA 14000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA012388: AB_1854860, HPA067448: AB_2685843" "unprognostic (2.61e-2)" "unprognostic (4.92e-1)" "unprognostic (2.44e-2)" "unprognostic (1.25e-2)" "unprognostic (1.09e-1)" "prognostic favorable (6.29e-4)" "unprognostic (6.50e-2)" "unprognostic (5.49e-2)" "unprognostic (2.07e-2)" "unprognostic (1.55e-1)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" ENHO "C9orf165, UNQ470" ENSG00000168913 "Energy homeostasis associated" Q6UWT2 9 34521043-34522990 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "brain: 542.2" "Cell type enhanced" "Detected in many" "Astrocytes: 67.5;Muller glia cells: 133.8;Oocytes: 27.9;Prostatic glandular cells: 65.3" "Cancer enhanced" "Detected in many" "glioma: 44.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "myeloid DC: 28.1" "Lineage enriched" "Detected in many" 8 "dendritic cells: 28.1" "Cancer enhanced" "Detected in many" "Neuroblastoma: 11.2" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042575 Approved "Secreted in brain" "No annotated function" NA NA 4240000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Muller glia cells - Visual perception" "HPA042575: AB_10794914" "unprognostic (2.63e-2)" "unprognostic (9.53e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.30e-1)" "unprognostic (7.51e-2)" "unprognostic (9.93e-2)" "unprognostic (1.34e-2)" "unprognostic (5.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.78e-4)" "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (6.47e-2)" "unprognostic (1.87e-1)" "unprognostic (5.50e-2)" "unprognostic (8.76e-2)" ENOX1 "cCNOX, CNOX, FLJ10094, PIG38" ENSG00000120658 "Ecto-NOX disulfide-thiol exchanger 1" Q8TC92 13 43213130-43786972 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 164.4;Early spermatids: 159.7;Excitatory neurons: 437.2;Inhibitory neurons: 663.8;Late spermatids: 271.0;Oligodendrocyte precursor cells: 157.5;Oligodendrocytes: 717.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 13.8" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038355 Approved Supported "Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 8: Neurons - Neuronal signaling" 5 "Plasma membrane" "HPA038355: AB_10673171" "unprognostic (9.64e-2)" "unprognostic (3.38e-3)" "unprognostic (1.64e-1)" "unprognostic (1.20e-3)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (2.88e-1)" "unprognostic (6.72e-3)" "unprognostic (2.60e-1)" "unprognostic (2.29e-3)" "unprognostic (1.32e-1)" "unprognostic (9.93e-2)" "unprognostic (1.32e-3)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.08e-3)" "unprognostic (1.42e-2)" ENOX2 "APK1, COVA1, tNOX" ENSG00000165675 "Ecto-NOX disulfide-thiol exchanger 2" Q16206 X 130622325-130903234 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Growth regulation, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 48.1;Oligodendrocytes: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000514, HPA003027" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Transport NA NA "Cluster 41: Basophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 11: White matter - Signal transduction" "Cluster 36: Non-specific - mRNA processing" "Cluster 51: Oligodendrocytes - Unknown function" Cytosol "Plasma membrane" "HPA000514: AB_1078558, HPA003027: " "unprognostic (1.34e-2)" "unprognostic (7.02e-2)" "unprognostic (9.75e-2)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "unprognostic (2.60e-1)" "unprognostic (4.07e-2)" "unprognostic (6.07e-2)" "unprognostic (6.27e-3)" "unprognostic (5.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.09e-5)" "unprognostic (6.42e-2)" "unprognostic (4.60e-2)" "unprognostic (3.02e-1)" "unprognostic (1.38e-1)" ENPP1 "M6S1, NPPS, PC-1, PCA1, PDNP1" ENSG00000197594 "Ectonucleotide pyrophosphatase/phosphodiesterase 1" P22413 6 131808016-131895155 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" Biomineralization Hydrolase "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 102.2;Endometrial stromal cells: 78.6;Hepatocytes: 95.2;Peritubular cells: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032904, HPA062066" Enhanced "Secreted - unknown location" Enzyme NA NA 4400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Liver - Plasma proteins" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 2 "CAB032904: AB_2099635, HPA062066: AB_2684674" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.60e-2)" "unprognostic (7.22e-3)" "unprognostic (8.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.00e-1)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (3.28e-3)" ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "choroid plexus: 1296.7" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 969.5" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 54.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 54.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 88.1" "Breast - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" Enzyme NA NA 1200000000 "Cluster 41: Basophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" ENPP3 "B10, CD203c, gp130RB13-6, PD-IBETA, PDNP3" ENSG00000154269 "Ectonucleotide pyrophosphatase/phosphodiesterase 3" O14638 6 131628442-131747418 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.0;intestine: 43.2" "Group enriched" "Detected in many" 6 "Basal prostatic cells: 243.7;Glandular and luminal cells: 368.2" "Cancer enriched" "Detected in many" 8 "renal cancer: 49.6" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 86 "basophil: 30.6" "Lineage enriched" "Detected in single" 86 "granulocytes: 30.6" "Cancer enhanced" "Detected in some" "Bone cancer: 4.1;Kidney cancer: 4.0;Leukemia: 6.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Mast cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA043772 Enhanced "Secreted - unknown location" Enzyme NA NA 1100000 "Cluster 46: Basophils - Proteolysis" "Cluster 45: Intestine - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA043772: AB_10795616" "unprognostic (2.74e-1)" "unprognostic (1.99e-2)" "unprognostic (1.84e-1)" "unprognostic (5.41e-3)" "unprognostic (6.07e-2)" "unprognostic (4.86e-5)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.96e-4)" "unprognostic (2.80e-2)" "unprognostic (7.85e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" ENPP5 ENSG00000112796 "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5" Q9UJA9 6 46159185-46170980 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 237.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 44.1;Muller glia cells: 78.5;Prostatic glandular cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.9" "Lineage enriched" "Detected in many" 5 "T-cells: 14.9" "Low cancer specificity" "Detected in many" "Skin - Eccrine sweat gland cells, Stomach - Parietal cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016902 Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA 620000 "Cluster 1: T-cells - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" Cytosol Nucleoplasm "HPA016902: AB_1848172" "unprognostic (1.12e-1)" "unprognostic (5.19e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-1)" "unprognostic (7.61e-2)" "unprognostic (1.63e-1)" "unprognostic (5.01e-2)" "prognostic favorable (4.57e-4)" "unprognostic (1.96e-1)" "unprognostic (9.89e-2)" "prognostic favorable (4.04e-4)" "unprognostic (7.00e-2)" "prognostic favorable (4.44e-13)" "unprognostic (4.40e-2)" "unprognostic (2.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.60e-1)" ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 27.8;kidney: 29.5;ovary: 15.6" "Cell type enhanced" "Detected in some" "Oligodendrocytes: 111.6;Peritubular cells: 33.9;Proximal tubular cells: 20.6" "Cancer enriched" "Detected in some" 5 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042740, HPA069197" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 290000 "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 51: Oligodendrocytes - Unknown function" "Golgi apparatus" "HPA042740: AB_10793984, HPA069197: " "unprognostic (4.81e-4)" "unprognostic (1.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.56e-1)" "unprognostic (6.69e-3)" "unprognostic (3.07e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.60e-3)" "unprognostic (3.04e-2)" "unprognostic (1.72e-1)" "unprognostic (2.98e-2)" "unprognostic (2.82e-1)" "unprognostic (3.93e-3)" "unprognostic (2.01e-1)" ENPP7 "alk-SMase, NPP7" ENSG00000182156 "Ectonucleotide pyrophosphatase/phosphodiesterase 7" Q6UWV6 17 79730943-79742219 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 101.7" "Group enriched" "Detected in some" 27 "Hepatocytes: 7.8;Proximal enterocytes: 27.7;Proximal tubular cells: 8.6" "Cancer enriched" "Detected in some" 6 "liver cancer: 6.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Myeloma: 1.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA024603 Approved "Intracellular and membrane" Enzyme NA NA 450000 "Cluster 25: Small intestine - Absorption" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 22: Proximal enterocytes - Digestion" 4 "HPA024603: AB_1848174" "unprognostic (4.00e-2)" "unprognostic (1.16e-2)" "unprognostic (6.49e-2)" "unprognostic (4.83e-2)" "unprognostic (1.55e-1)" "unprognostic (2.65e-2)" "unprognostic (1.24e-1)" "unprognostic (1.01e-1)" "unprognostic (8.45e-4)" "unprognostic (4.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (5.21e-2)" "unprognostic (1.25e-1)" "unprognostic (1.80e-2)" ENSG00000267335 ENSG00000267335 "Novel protein" 19 49022953-49036895 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "pituitary gland: 16.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA038925 Uncertain "Secreted - unknown location" NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 50: Lymphoma - Unknown function" "HPA038925: AB_2676272" ENSG00000275063 ENSG00000275063 P0DP08 Unmapped 41444-41876 "Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 600.5;lymphoid tissue: 742.7;urinary bladder: 419.4" "Cell type enriched" "Detected in some" 186 "Plasma cells: 2639.7" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 368 "memory B-cell: 404.4;naive B-cell: 260.3" "Lineage enriched" "Detected in single" 447 "B-cells: 404.4" "Cancer enriched" "Detected in some" 4 "lymphoma: 47.9" "Secreted to blood" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 13: Non-specific - Mixed function" "Cluster 23: Plasma cells - Humoral immune response" ENSG00000277400 ENSG00000277400 Q8WZ33 Unmapped 53590-115018 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Ductal cells: 3.9;Exocrine glandular cells: 2.3;Pancreatic endocrine cells: 3.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Intracellular and membrane" Transcription NA NA "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 45: Non-specific - Mixed function" ENSG00000284779 ENSG00000284779 "Novel protein" 11 2131395-2149603 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Sarcoma: 1.9" "Not detected" "Not detected" HPA071234 Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 33: Sarcoma - Muscle contraction" "Cluster 43: Hepatocytes - Metabolism" Nucleoplasm "HPA071234: " ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)" O75356 14 73958010-74019399 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 103.8;kidney: 91.8;liver: 255.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 190.4;Hepatocytes: 115.5;Intestinal goblet cells: 86.4;Prostatic glandular cells: 78.6;Proximal enterocytes: 79.9" "Group enriched" "Detected in all" 5 "liver cancer: 18.2;prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.4;eosinophil: 9.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 18.4" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" Enzyme NA NA 5900000 "Cluster 46: Basophils - Proteolysis" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 2 "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" ENTPD6 "CD39L2, dJ738P15.3, IL6ST2, NTPDase-6" ENSG00000197586 "Ectonucleoside triphosphate diphosphohydrolase 6" O75354 20 25195693-25228075 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015491, HPA069555" Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA 41000 "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 16: Intestinal goblet cells - Mucin production" "Golgi apparatus" "HPA015491: AB_2669200, HPA069555: AB_2686152" "unprognostic (3.24e-1)" "unprognostic (1.27e-2)" "unprognostic (5.91e-2)" "unprognostic (1.16e-1)" "unprognostic (1.76e-1)" "unprognostic (4.44e-1)" "unprognostic (2.10e-3)" "unprognostic (7.41e-3)" "unprognostic (2.74e-3)" "unprognostic (1.17e-1)" "unprognostic (2.14e-1)" "unprognostic (1.03e-1)" "unprognostic (8.14e-3)" "unprognostic (1.78e-2)" "unprognostic (2.74e-1)" "unprognostic (4.86e-2)" "unprognostic (4.48e-2)" EOGT "AER61, C3orf64, FLJ33770" ENSG00000163378 "EGF domain specific O-linked N-acetylglucosamine transferase" Q5NDL2 3 68975217-69013684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019460 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Smooth muscle cells - Muscle contraction" "Nucleoplasm, Nuclear membrane" Cytosol "HPA019460: AB_1844628" "unprognostic (2.62e-1)" "unprognostic (3.72e-1)" "unprognostic (1.07e-1)" "unprognostic (1.95e-2)" "unprognostic (8.96e-2)" "unprognostic (6.30e-2)" "unprognostic (2.18e-3)" "unprognostic (6.66e-2)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (8.97e-5)" "unprognostic (7.41e-2)" "unprognostic (4.67e-1)" "unprognostic (3.44e-2)" "unprognostic (2.04e-1)" EPDR1 "EPDR, MERP-1, MERP1, UCC1" ENSG00000086289 "Ependymin related 1" Q9UM22 7 37920640-37951936 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 117.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 53.8;Alveolar cells type 2: 73.2;Granulosa cells: 51.4;Peritubular cells: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Kidney cancer: 143.0" "Breast - Adipocytes (Breast), Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026298, HPA072321" Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 6: Ovarian stromal cells - Transcription" 10 "CAB026298: AB_425991, HPA072321: " "unprognostic (1.99e-2)" "unprognostic (9.30e-2)" "unprognostic (4.44e-3)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (4.85e-2)" "prognostic unfavorable (6.97e-4)" "unprognostic (2.53e-2)" "unprognostic (2.75e-1)" "unprognostic (3.13e-1)" "unprognostic (7.23e-2)" "unprognostic (1.85e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (4.13e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.00e-4)" EPGN "ALGV3072, EPG, PRO9904" ENSG00000182585 "Epithelial mitogen" Q6UW88 4 74308470-74316789 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 47.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 13.2;Basal squamous epithelial cells: 12.9;Mesothelial cells: 22.1;Squamous epithelial cells: 7.5;Suprabasal keratinocytes: 35.1" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014420 Approved Nucleoplasm,Vesicles,Cytosol "Secreted in other tissues" "Growth factor" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Nucleoplasm, Cytosol" Vesicles "HPA014420: AB_10601551" "unprognostic (7.51e-2)" "unprognostic (8.08e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" "unprognostic (2.38e-4)" "unprognostic (2.20e-1)" "unprognostic (2.01e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (4.06e-4)" "unprognostic (3.84e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.40e-4)" EPHA10 "FLJ16103, FLJ33655" ENSG00000183317 "EPH receptor A10" Q5JZY3 1 37713880-37765133 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.3;intestine: 13.1;testis: 13.0" "Group enriched" "Detected in some" 4 "Early spermatids: 52.2;Late spermatids: 178.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027497 Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 25: Small intestine - Absorption" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 36: Late spermatids - Unknown function" "HPA027497: AB_10601158" "unprognostic (9.27e-2)" "unprognostic (1.21e-1)" "unprognostic (2.94e-2)" "unprognostic (1.24e-6)" "unprognostic (1.06e-1)" "unprognostic (1.11e-2)" "unprognostic (5.39e-2)" "unprognostic (1.25e-1)" "unprognostic (2.55e-2)" "unprognostic (1.40e-1)" "unprognostic (7.06e-3)" "unprognostic (1.50e-1)" "unprognostic (8.81e-5)" "unprognostic (2.55e-2)" "unprognostic (2.97e-2)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 30.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 68.2;Inhibitory neurons: 101.4;Microglial cells: 98.4;Oligodendrocytes: 44.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" 2 "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" EPHA7 Hek11 ENSG00000135333 "EPH receptor A7" Q15375 6 93240020-93419687 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 23.8;parathyroid gland: 67.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 133.8;Inhibitory neurons: 164.5" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 33.5;Sarcoma: 26.4" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 81.6" CAB010496 Approved "Intracellular and membrane" Receptor NA NA 660000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 6 "CAB010496: AB_2099673" "unprognostic (3.34e-1)" "unprognostic (7.82e-2)" "unprognostic (1.41e-1)" "unprognostic (9.32e-2)" "unprognostic (1.19e-1)" "unprognostic (3.56e-2)" "unprognostic (1.62e-2)" "unprognostic (4.07e-1)" "unprognostic (4.16e-2)" "unprognostic (3.19e-2)" "unprognostic (5.69e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.56e-2)" "unprognostic (4.82e-2)" EPHA8 "EEK, Hek3" ENSG00000070886 "EPH receptor A8" P29322 1 22563489-22603595 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "choroid plexus: 32.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.6;Early spermatids: 2.4;Horizontal cells: 5.0;Late spermatids: 4.5;Oocytes: 5.1;Rod photoreceptor cells: 9.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enriched" "Detected in all" 5 "choroid plexus: 62.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 4.0" "Region enhanced" "Detected in many" "cerebellum: 13.0" "Region enriched" "Detected in many" 5 "cerebellum: 17.6" "CAB009660, HPA031433" Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "CAB009660: AB_2099696, HPA031433: AB_10601371" "unprognostic (8.58e-2)" "unprognostic (8.59e-2)" "unprognostic (3.72e-1)" "unprognostic (1.15e-2)" "unprognostic (4.69e-4)" "unprognostic (3.58e-1)" "unprognostic (7.14e-2)" "unprognostic (1.52e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.10e-1)" "unprognostic (9.84e-14)" "unprognostic (2.14e-3)" "unprognostic (1.69e-1)" "unprognostic (2.76e-1)" "unprognostic (8.68e-2)" EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.6" "Cell type enhanced" "Detected in many" "Ductal cells: 43.8;Enteroendocrine cells: 54.0;Intestinal goblet cells: 42.4;Oligodendrocytes: 71.0;Undifferentiated cells: 92.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor No No 380000 "Cluster 45: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 16: Intestinal goblet cells - Mucin production" 4 "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" EPHB6 HEP ENSG00000106123 "EPH receptor B6" 7 142855061-142871094 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 59.5;skin 1: 63.8" "Cell type enhanced" "Detected in many" "Mesothelial cells: 181.6;Muller glia cells: 193.3;Prostatic glandular cells: 76.9;Suprabasal keratinocytes: 105.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 70.9;cerebral cortex: 120.2;white matter: 83.2" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035784 Uncertain "Nuclear speckles" "Intracellular and membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 80: Non-specific - Endocytosis" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 10: Muller glia cells - Visual perception" "Nuclear speckles" "HPA035784: AB_2674781" "unprognostic (1.90e-2)" "prognostic favorable (1.80e-4)" "unprognostic (7.08e-3)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (2.53e-3)" "unprognostic (3.15e-2)" "unprognostic (4.39e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.06e-3)" "unprognostic (3.18e-1)" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (4.93e-2)" "unprognostic (3.16e-1)" "prognostic favorable (4.68e-5)" EPHX3 "ABHD9, FLJ22408" ENSG00000105131 "Epoxide hydrolase 3" Q9H6B9 19 15226919-15233435 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 67.0;skin 1: 74.1;vagina: 35.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 14.8;Club cells: 18.4;Ionocytes: 14.4;Serous glandular cells: 13.3;Squamous epithelial cells: 37.2;Suprabasal keratinocytes: 67.7" "Cancer enhanced" "Detected in many" "cervical cancer: 30.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 19 "dendritic cells: 1.3;monocytes: 2.4" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.7;testis cancer: 3.1" "Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012842 Uncertain Approved Nucleoplasm "Intracellular and membrane" Enzyme NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA012842: AB_10601648" "unprognostic (1.39e-1)" "unprognostic (1.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.74e-1)" "unprognostic (8.24e-2)" "prognostic favorable (2.27e-5)" "unprognostic (8.83e-3)" "unprognostic (1.50e-1)" "unprognostic (3.90e-1)" "unprognostic (4.36e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-1)" "unprognostic (3.68e-2)" "unprognostic (1.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.01e-2)" EPO EP ENSG00000130427 Erythropoietin P01588 7 100720468-100723700 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Erythrocyte maturation" Hormone "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 46.0" "Group enriched" "Detected in some" 4 "Exocrine glandular cells: 6.4;Extravillous trophoblasts: 16.8;Hepatocytes: 18.5" "Group enriched" "Detected in many" 5 "liver cancer: 2.7;renal cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" CAB010336 Supported "Secreted to blood" Hormone NA NA 12300 "Cluster 83: Liver - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 2 "CAB010336: AB_2098408" "unprognostic (2.93e-1)" "unprognostic (1.57e-2)" "unprognostic (1.08e-3)" "unprognostic (7.30e-2)" "unprognostic (1.09e-1)" "unprognostic (1.78e-3)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.52e-2)" "unprognostic (5.16e-2)" "unprognostic (9.70e-2)" "unprognostic (2.44e-3)" "unprognostic (3.31e-1)" "prognostic unfavorable (2.18e-6)" "unprognostic (4.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (3.34e-1)" EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 84.7;Hofbauer cells: 37.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" Receptor NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Thyroid gland - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 4 "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" EPPIN "CT71, dJ461P17.2, EPPIN1, EPPIN2, EPPIN3, SPINLW1, WAP7, WFDC7" ENSG00000101448 "Epididymal peptidase inhibitor" O95925 20 45540626-45547752 "Predicted intracellular proteins, Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 87 "epididymis: 319.7;testis: 81.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 21.4;Granulosa cells: 31.7;Late spermatids: 22.9;Sertoli cells: 119.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067335 Supported "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 42: Ciliated cells - Cilium assembly" "HPA067335: " "unprognostic (1.17e-1)" "unprognostic (1.79e-1)" "unprognostic (3.08e-3)" "unprognostic (1.06e-2)" "unprognostic (3.75e-2)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (2.00e-2)" EPPIN-WFDC6 SPINLW1-WFDC6 ENSG00000249139 "EPPIN-WFDC6 readthrough" O95925 20 45534196-45547662 "Predicted secreted proteins" "Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 79 "epididymis: 62.3;testis: 52.0" "Cell type enriched" "Detected in single" 7 "Sertoli cells: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA067335 Supported "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 63: Testis - Spermatid development" "Cluster 15: Kidney cancer - Membrane components" "Cluster 6: Ovarian stromal cells - Transcription" "HPA067335: " "unprognostic (1.46e-3)" "unprognostic (6.38e-2)" EPS15 "AF-1P, MLLT5" ENSG00000085832 "Epidermal growth factor receptor pathway substrate 15" P42566 1 51354263-51519328 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Host-virus interaction, Protein transport, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 292.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008451, CAB010164, HPA061431" Approved Enhanced Vesicles,Cytosol "Intracellular and membrane" Transport NA NA 65000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Oligodendrocytes - Unknown function" 9 "Vesicles, Cytosol" "CAB010164: AB_631445, HPA008451: AB_1848221, HPA061431: AB_2732662" "unprognostic (1.45e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.05e-2)" "unprognostic (7.72e-3)" "unprognostic (3.99e-1)" "unprognostic (1.42e-1)" "unprognostic (4.96e-3)" "unprognostic (9.26e-2)" "unprognostic (4.13e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (5.36e-2)" "unprognostic (8.73e-3)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" EPYC "DSPG3, Pg-Lb, SLRR3B" ENSG00000083782 Epiphycan Q99645 12 90963682-91005026 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "placenta: 6.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "breast cancer: 2.4;ovarian cancer: 7.7;pancreatic cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Rhabdoid: 25.9;Sarcoma: 10.8" "Region enhanced" "Detected in single" "midbrain: 1.4" "Low region specificity" "Detected in all" "HPA038212, HPA045455" Approved "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 2 "HPA038212: AB_10672739, HPA045455: AB_2679330" "unprognostic (2.25e-1)" "unprognostic (2.08e-1)" "unprognostic (2.79e-1)" "unprognostic (4.28e-2)" "unprognostic (1.81e-2)" "unprognostic (4.07e-2)" "unprognostic (9.20e-2)" "unprognostic (3.23e-1)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.77e-2)" "unprognostic (6.44e-9)" "unprognostic (2.83e-2)" "unprognostic (3.08e-1)" "unprognostic (8.68e-2)" "unprognostic (1.20e-1)" EQTN "AFAF, C9orf11, equatorin, SPACA8" ENSG00000120160 Equatorin Q9NQ60 9 27284654-27297150 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 53 "testis: 36.7" "Cell type enriched" "Detected in some" 18 "Early spermatids: 997.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA015089, HPA015504" Enhanced Approved "Plasma membrane,Actin filaments" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 18: Early spermatids - Unknown function" "Plasma membrane, Actin filaments" "HPA015089: AB_1845795, HPA015504: AB_2067598" "unprognostic (7.83e-2)" "unprognostic (1.55e-1)" "unprognostic (5.64e-2)" "unprognostic (8.12e-3)" "unprognostic (1.34e-3)" "unprognostic (4.41e-2)" "unprognostic (3.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.32e-1)" "unprognostic (1.89e-1)" "unprognostic (5.67e-2)" "unprognostic (1.14e-1)" "unprognostic (4.59e-2)" "unprognostic (8.46e-2)" "unprognostic (3.90e-2)" "unprognostic (1.42e-1)" ERAP1 "A-LAP, ARTS-1, ERAAP1, KIAA0525, PILS-AP" ENSG00000164307 "Endoplasmic reticulum aminopeptidase 1" Q9NZ08 5 96760810-96808100 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.3;Inhibitory neurons: 76.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025095, HPA042317" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA NA 30000000 "Cluster 1: T-cells - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 30: White matter - Myelination" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 15: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB025095: , HPA042317: AB_2677946" "unprognostic (2.33e-3)" "unprognostic (3.45e-1)" "unprognostic (1.84e-3)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.38e-1)" "unprognostic (1.88e-3)" "unprognostic (5.37e-2)" "unprognostic (1.45e-1)" "unprognostic (7.94e-2)" "unprognostic (4.52e-2)" "unprognostic (3.23e-1)" "unprognostic (7.09e-2)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (5.14e-2)" ERAP2 "L-RAP, LRAP" ENSG00000164308 "Endoplasmic reticulum aminopeptidase 2" Q6P179 5 96875986-96919703 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025618, HPA034498, HPA064360" Enhanced Approved "Golgi apparatus" "Secreted to blood" Immunity NA NA 11000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Langerhans cells - Innate immune response" "Golgi apparatus" "CAB025618: , HPA034498: AB_2674191, HPA064360: " "unprognostic (4.62e-2)" "unprognostic (1.60e-1)" "unprognostic (4.98e-2)" "unprognostic (1.56e-1)" "unprognostic (3.14e-1)" "unprognostic (8.71e-2)" "unprognostic (2.60e-2)" "unprognostic (1.17e-2)" "unprognostic (5.03e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.01e-1)" "unprognostic (9.54e-3)" "unprognostic (6.59e-2)" "unprognostic (8.48e-2)" "unprognostic (4.65e-2)" "unprognostic (3.05e-1)" ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 207.6;Schwann cells: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" Receptor NA NA 450000 "Cluster 48: Stomach - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" 19 "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" EREG ER ENSG00000124882 Epiregulin O14944 4 74365145-74388749 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 127.2" "Cell type enriched" "Detected in many" 4 "monocytes: 3221.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 126.8" "Adipose visceral - Neutrophils, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047186, HPA054373" Uncertain Vesicles "Secreted to blood" "Growth factor" NA NA 46000 "Cluster 6: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 5 Vesicles "HPA047186: , HPA054373: " "unprognostic (1.26e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (4.56e-3)" "unprognostic (3.94e-2)" "unprognostic (2.24e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (6.57e-5)" "unprognostic (2.94e-1)" "unprognostic (1.70e-6)" "unprognostic (2.42e-2)" "unprognostic (1.13e-2)" "unprognostic (6.59e-3)" "unprognostic (3.16e-3)" ERFE "C1QTNF15, CTRP15, FAM132B, FLJ37034" ENSG00000178752 Erythroferrone Q4G0M1 2 238158970-238168900 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 11.4;skeletal muscle: 14.4;testis: 12.4;thyroid gland: 24.1" "Cell type enhanced" "Detected in some" "Early spermatids: 55.8;Erythroid cells: 22.5;Late spermatids: 17.4;Oocytes: 11.0;Skeletal myocytes: 8.8;Spermatocytes: 21.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 25.9" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted to blood" Hormone NA NA 277000 "Cluster 78: Testis - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "unprognostic (1.66e-1)" "unprognostic (9.14e-2)" "unprognostic (3.64e-4)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.84e-1)" "unprognostic (9.61e-4)" "unprognostic (4.68e-3)" "unprognostic (3.16e-3)" "unprognostic (9.63e-2)" "unprognostic (9.11e-2)" "unprognostic (1.31e-4)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (4.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.33e-2)" ERLEC1 "C2orf30, CL25084, ERLECTIN, XTP3-B, XTP3TPB" ENSG00000068912 "Endoplasmic reticulum lectin 1" Q96DZ1 2 53787009-53833038 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 440.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031501, HPA031502, HPA031503" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" "HPA031501: AB_10600104, HPA031502: AB_10602174, HPA031503: AB_10670425" "unprognostic (1.27e-2)" "unprognostic (3.36e-3)" "unprognostic (3.17e-1)" "unprognostic (1.97e-3)" "unprognostic (1.08e-2)" "unprognostic (1.86e-1)" "unprognostic (3.27e-3)" "unprognostic (3.79e-1)" "unprognostic (1.29e-1)" "unprognostic (2.95e-2)" "unprognostic (1.82e-1)" "unprognostic (1.92e-1)" "unprognostic (4.71e-2)" "unprognostic (1.47e-1)" "unprognostic (8.13e-2)" "unprognostic (2.33e-2)" "unprognostic (3.92e-2)" ERLIN1 "C10orf69, Erlin-1, KE04, SPFH1, SPG62" ENSG00000107566 "ER lipid raft associated 1" O75477 10 100150094-100186033 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 110.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 68.5;Hepatocytes: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" HPA011252 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 4: Extravillous trophoblasts - Unknown function" 11 "Endoplasmic reticulum" "HPA011252: AB_1853965" "unprognostic (3.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (6.98e-3)" "unprognostic (2.69e-1)" "unprognostic (1.70e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (7.63e-4)" "unprognostic (1.26e-1)" "unprognostic (9.68e-2)" "unprognostic (1.99e-3)" "unprognostic (9.09e-2)" "unprognostic (1.32e-3)" "unprognostic (6.10e-3)" "unprognostic (1.76e-1)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" ERLIN2 "C8orf2, Erlin-2, NET32, SPFH2, SPG18" ENSG00000147475 "ER lipid raft associated 2" O94905 8 37736601-37758422 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002025, CAB014894" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 5 "Endoplasmic reticulum" "CAB014894: , HPA002025: AB_1080077" "unprognostic (5.82e-3)" "unprognostic (2.45e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.39e-2)" "unprognostic (1.89e-1)" "unprognostic (3.77e-2)" "unprognostic (6.67e-2)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.78e-3)" "prognostic favorable (6.67e-6)" "unprognostic (4.78e-2)" "unprognostic (2.83e-1)" "unprognostic (3.43e-1)" "unprognostic (2.33e-1)" ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690310-23713226 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 18.7;gallbladder: 16.4;intestine: 28.0;salivary gland: 22.2;stomach 1: 50.5" "Cell type enhanced" "Detected in some" "Club cells: 56.5;Distal enterocytes: 92.0;Enteroendocrine cells: 39.6;Gastric mucus-secreting cells: 159.2;Intestinal goblet cells: 147.0;Ionocytes: 59.6;Undifferentiated cells: 37.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.0;pancreatic cancer: 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 13.3;colorectal cancer: 19.5;Gallbladder cancer: 8.9;Gastric cancer: 16.2;pancreatic cancer: 8.7" "Breast - Adipocytes (Breast), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA076875 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Transcription NA NA "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "Endoplasmic reticulum, Cytosol" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" ERO1A "ERO1-alpha, Ero1alpha, ERO1L" ENSG00000197930 "Endoplasmic reticulum oxidoreductase 1 alpha" Q96HE7 14 52639915-52695900 "Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 167.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 431.0;Club cells: 218.4;Ductal cells: 217.4;Extravillous trophoblasts: 244.1;Ionocytes: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026653, HPA030053, CAB034294" Enhanced "Intracellular and membrane" Transport NA NA 110000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 6 "CAB034294: AB_2098744, HPA026653: AB_1848254, HPA030053: AB_10601467" "unprognostic (8.64e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.86e-2)" "unprognostic (5.89e-2)" "unprognostic (5.69e-3)" "unprognostic (4.23e-2)" "prognostic unfavorable (7.59e-4)" "prognostic unfavorable (1.10e-5)" "unprognostic (4.98e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (2.27e-4)" "unprognostic (3.17e-1)" "prognostic unfavorable (6.54e-9)" "unprognostic (9.19e-2)" "unprognostic (2.78e-2)" "unprognostic (4.58e-1)" "unprognostic (5.03e-2)" ERO1B "ERO1-L(beta), Ero1beta, ERO1LB" ENSG00000086619 "Endoplasmic reticulum oxidoreductase 1 beta" Q86YB8 1 236214681-236282019 "Predicted intracellular proteins" "Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 177.1" "Cell type enhanced" "Detected in many" "Early spermatids: 156.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028085 Enhanced "Intracellular and membrane" Transport NA NA "Cluster 41: Basophils - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Dendritic cells - Antigen presentation" "HPA028085: AB_10601214" "unprognostic (1.16e-1)" "unprognostic (1.33e-3)" "unprognostic (1.00e-1)" "unprognostic (1.41e-1)" "unprognostic (1.07e-1)" "unprognostic (9.80e-2)" "unprognostic (2.49e-2)" "prognostic favorable (7.53e-5)" "unprognostic (1.73e-2)" "unprognostic (2.85e-2)" "unprognostic (4.65e-2)" "unprognostic (5.90e-2)" "unprognostic (8.26e-3)" "unprognostic (7.87e-2)" "unprognostic (3.37e-1)" "unprognostic (2.22e-3)" "unprognostic (8.09e-3)" ERP27 "C12orf46, FLJ32115, PDIA8" ENSG00000139055 "Endoplasmic reticulum protein 27" Q96DN0 12 14914039-14938537 "Predicted intracellular proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "pancreas: 1746.8" "Group enriched" "Detected in many" 4 "Distal tubular cells: 264.3;Secretory cells: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bile duct cancer: 23.7" "Pancreas - Exocrine glandular cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA039636, HPA052851" Enhanced "Intracellular and membrane" Other NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Pancreas - Proteolysis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 10 "HPA039636: AB_10795403, HPA052851: AB_2681972" "unprognostic (9.02e-3)" "unprognostic (2.53e-1)" "unprognostic (1.41e-1)" "unprognostic (4.69e-2)" "unprognostic (8.70e-2)" "unprognostic (3.92e-3)" "unprognostic (2.70e-1)" "unprognostic (1.48e-2)" "unprognostic (2.37e-3)" "unprognostic (5.33e-2)" "unprognostic (2.34e-2)" "unprognostic (1.88e-1)" "unprognostic (7.89e-2)" "unprognostic (4.55e-2)" "unprognostic (8.98e-2)" "unprognostic (1.76e-3)" "unprognostic (3.45e-2)" ERP29 "C12orf8, ERp28, ERp31, PDI-DB, PDIA9" ENSG00000089248 "Endoplasmic reticulum protein 29" P30040 12 112013348-112023449 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039363, HPA039456" Enhanced Uncertain Nucleoplasm,Microtubules "Intracellular and membrane" "No annotated function" NA NA 900000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 28: Dendritic cells - Antigen presentation" 16 Microtubules Nucleoplasm "HPA039363: AB_10673422, HPA039456: AB_10672963" "unprognostic (2.70e-2)" "unprognostic (1.16e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.43e-5)" "unprognostic (1.13e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" "unprognostic (5.10e-3)" "unprognostic (2.58e-1)" "unprognostic (3.21e-1)" "unprognostic (2.74e-3)" "unprognostic (3.34e-1)" "unprognostic (1.76e-1)" "unprognostic (6.26e-2)" ERP44 "KIAA0573, PDIA10, TXNDC4" ENSG00000023318 "Endoplasmic reticulum protein 44" Q9BS26 9 99979185-100099052 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001318 Supported "Intracellular and membrane" Other NA NA 5300000 "Cluster 40: Monocytes - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 2: Neurons - Nucleosome" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 4 "HPA001318: AB_1080427" "unprognostic (8.28e-2)" "unprognostic (1.32e-1)" "unprognostic (5.56e-2)" "unprognostic (5.97e-3)" "unprognostic (1.55e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (1.29e-1)" "unprognostic (3.88e-2)" "unprognostic (2.58e-1)" "unprognostic (2.00e-2)" "unprognostic (5.38e-2)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-1)" "unprognostic (1.66e-1)" "unprognostic (3.90e-1)" "unprognostic (2.31e-1)" ERVH48-1 "C21orf105, NDUFV3-AS1, SUPYN" ENSG00000233056 "Endogenous retrovirus group 48 member 1" M5A8F1 21 42916803-42925630 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 98 "placenta: 148.0" "Group enriched" "Detected in some" 21 "Cytotrophoblasts: 132.0;Extravillous trophoblasts: 280.0;Syncytiotrophoblasts: 77.7" "Cancer enriched" "Detected in some" 18 "testis cancer: 74.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 7.8" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.8" "Cancer enriched" "Detected in many" 5 "testis cancer: 41.3" "Prostate - Prostate glandular cells" "Secreted in female reproductive system" "No annotated function" NA NA 57000 "Cluster 21: Neutrophils - Unknown function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (5.28e-2)" "unprognostic (5.92e-2)" "unprognostic (5.66e-2)" "unprognostic (9.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" "unprognostic (1.92e-2)" "unprognostic (3.48e-1)" "unprognostic (1.52e-2)" "unprognostic (7.74e-2)" "unprognostic (3.12e-3)" "unprognostic (1.57e-1)" "unprognostic (1.81e-1)" "unprognostic (1.83e-2)" "unprognostic (1.08e-2)" ERVMER34-1 envMER34 ENSG00000226887 "Endogenous retrovirus group MER34 member 1, envelope" Q9H9K5 4 52722618-52751586 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 12.5;placenta: 10.5" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 80.5;Extravillous trophoblasts: 96.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA011423, HPA024053" Approved Approved Nucleoplasm,Cytosol "Secreted to blood" "No annotated function" NA NA 6000000 "Cluster 58: Placenta - Pregnancy" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 4: Extravillous trophoblasts - Unknown function" Nucleoplasm Cytosol "HPA011423: AB_2668510, HPA024053: " "unprognostic (5.34e-2)" "unprognostic (1.29e-1)" "unprognostic (1.91e-3)" "unprognostic (5.86e-2)" "unprognostic (4.08e-4)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.88e-4)" "unprognostic (5.28e-2)" "unprognostic (2.99e-2)" "unprognostic (2.39e-3)" "unprognostic (2.62e-3)" "unprognostic (4.23e-2)" "unprognostic (1.03e-2)" "unprognostic (1.32e-2)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" "unprognostic (1.82e-1)" ESM1 ENSG00000164283 "Endothelial cell specific molecule 1" Q9NQ30 5 54977867-55022671 "Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 19.2;thyroid gland: 16.8" "Cell type enhanced" "Detected in some" "Ductal cells: 18.2;Endothelial cells: 81.9;Mucus glandular cells: 21.5;Pancreatic endocrine cells: 17.0" "Cancer enriched" "Detected in all" 8 "renal cancer: 65.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "ovarian cancer: 67.4;Sarcoma: 47.6;thyroid cancer: 85.4" "Low region specificity" "Detected in single" "Region enhanced" "Detected in some" "midbrain: 3.6" CAB047364 Approved "Secreted to blood" "Developmental protein" NA NA 1540000 340000 "Cluster 1: T-cells - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 7 "CAB047364: " "unprognostic (4.70e-2)" "prognostic unfavorable (2.11e-7)" "unprognostic (2.63e-3)" "unprognostic (2.31e-3)" "unprognostic (4.68e-2)" "unprognostic (1.55e-1)" "unprognostic (6.85e-3)" "unprognostic (1.59e-2)" "unprognostic (1.05e-1)" "unprognostic (1.78e-3)" "unprognostic (1.18e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (4.00e-4)" "unprognostic (7.77e-2)" "unprognostic (1.09e-1)" "unprognostic (7.84e-2)" "unprognostic (2.94e-1)" ESRP1 "FLJ20171, RBM35A" ENSG00000104413 "Epithelial splicing regulatory protein 1" Q6NXG1 8 94641074-94707466 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.7;Intestinal goblet cells: 97.3;Suprabasal keratinocytes: 93.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023719, HPA023720, HPA067104" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Other NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 28 "Nuclear bodies" Nucleoplasm "HPA023719: AB_1856124, HPA023720: AB_1856125, HPA067104: AB_2685779" "prognostic unfavorable (9.28e-4)" "unprognostic (7.12e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.12e-1)" "unprognostic (6.99e-3)" "unprognostic (2.70e-1)" "unprognostic (2.61e-2)" "unprognostic (5.19e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (4.48e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.96e-2)" "unprognostic (1.29e-1)" EXOG "ENDOGL1, ENDOGL2, ENGL, ENGL-a, ENGL-b" ENSG00000157036 "Exo/endonuclease G" Q9Y2C4 3 38496127-38542161 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012531, HPA071050" Enhanced Supported Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 30: Heart muscle - Heart development" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" Mitochondria "HPA012531: AB_2732403, HPA071050: " "unprognostic (2.88e-1)" "unprognostic (5.81e-3)" "unprognostic (3.55e-3)" "unprognostic (2.77e-1)" "unprognostic (8.32e-3)" "unprognostic (8.90e-3)" "unprognostic (4.78e-4)" "unprognostic (3.59e-2)" "unprognostic (3.99e-2)" "unprognostic (3.10e-2)" "prognostic favorable (1.92e-5)" "prognostic unfavorable (4.90e-4)" "unprognostic (6.51e-2)" "unprognostic (1.64e-2)" "unprognostic (4.79e-2)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" EXTL1 "EXTL, MGC70794" ENSG00000158008 "Exostosin like glycosyltransferase 1" Q92935 1 26019884-26036464 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 31.6;skeletal muscle: 12.2;tongue: 28.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.8;Breast glandular cells: 8.5;Excitatory neurons: 22.0;Horizontal cells: 6.9;Melanocytes: 8.6;Oligodendrocyte precursor cells: 9.9" "Cancer enriched" "Detected in some" 13 "melanoma: 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Rhabdoid: 8.6;skin cancer: 25.6" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010726, HPA037749" Uncertain Approved Vesicles,Centrosome "Intracellular and membrane" Enzyme NA NA 79000 "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 17: Breast glandular cells - Lactation" 4 Centrosome Vesicles "HPA010726: , HPA037749: AB_10805350" "unprognostic (2.00e-1)" "unprognostic (1.10e-2)" "unprognostic (8.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.47e-2)" "unprognostic (6.14e-3)" "unprognostic (3.78e-2)" "unprognostic (1.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.44e-2)" "unprognostic (3.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-3)" "unprognostic (2.27e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-2)" EXTL2 ENSG00000162694 "Exostosin like glycosyltransferase 2" Q9UBQ6 1 100872372-100895179 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 216.6;Syncytiotrophoblasts: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 84.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020716, HPA068921" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA 80000000 "Cluster 41: Basophils - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Cytotrophoblasts - Mitochondria" 3 Nucleoplasm Cytosol "CAB020716: , HPA068921: AB_2686058" "unprognostic (3.14e-1)" "unprognostic (6.34e-2)" "unprognostic (1.50e-2)" "unprognostic (8.20e-2)" "unprognostic (9.07e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (7.81e-3)" "unprognostic (1.10e-2)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" "unprognostic (3.00e-1)" "unprognostic (3.17e-2)" "unprognostic (6.84e-2)" "unprognostic (7.83e-2)" "unprognostic (1.24e-2)" "unprognostic (4.34e-2)" EYS "bA166P24.2, bA307F22.3, bA74E24.1, C6orf178, C6orf179, C6orf180, dJ1018A4.2, dJ303F19.1, EGFL10, EGFL11, RP25, SPAM" ENSG00000188107 "Eyes shut homolog" Q5T1H1 6 63719980-65707226 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "retina: 24.2" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 154.6;Early spermatids: 104.3;Inhibitory neurons: 80.2;Late spermatids: 44.4;Rod photoreceptor cells: 159.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.4" "Testis - Early spermatids, Testis - Late spermatids" "Secreted in other tissues" Other NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "unprognostic (2.92e-2)" "unprognostic (1.90e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-2)" "unprognostic (2.16e-3)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (6.38e-2)" "unprognostic (3.67e-1)" "unprognostic (1.97e-1)" "unprognostic (2.04e-1)" "unprognostic (2.18e-1)" "unprognostic (2.61e-4)" "unprognostic (1.89e-1)" "unprognostic (8.41e-2)" "unprognostic (6.38e-3)" "unprognostic (1.11e-1)" F10 ENSG00000126218 "Coagulation factor X" P00742 13 113122799-113149529 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 156.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 109.1;Hepatocytes: 170.7;Leydig cells: 217.7;Peritubular cells: 232.6;Smooth muscle cells: 57.6" "Cancer enriched" "Detected in many" 11 "liver cancer: 95.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 6.9;liver cancer: 16.8" "Breast - Fibroblasts, Colon - Fibroblasts, Liver - Hepatocytes, Pancreas - Alpha cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" "Blood coagulation" NA NA 13000000000 "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 53: Fibroblasts - ECM organization" 3 "unprognostic (4.18e-2)" "unprognostic (1.07e-1)" "unprognostic (7.62e-2)" "unprognostic (9.88e-2)" "unprognostic (9.44e-2)" "unprognostic (1.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "prognostic favorable (1.82e-5)" "unprognostic (6.39e-2)" "prognostic unfavorable (5.14e-5)" "unprognostic (6.60e-2)" "unprognostic (1.21e-1)" "unprognostic (3.87e-2)" "unprognostic (2.23e-3)" F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 235.6" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 69.2" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.8" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039808 Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 4400000000 "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" F12 ENSG00000131187 "Coagulation factor XII" P00748 5 177402133-177416583 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 311 "liver: 589.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 375.4" "Cancer enriched" "Detected in many" 21 "liver cancer: 171.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 1.7" "Lineage enhanced" "Detected in single" "granulocytes: 1.7" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA003825 Approved "Secreted to blood" "Blood coagulation" NA NA 1040000 7000000000 "Cluster 19: Eosinophils - Unknown function" "Cluster 31: Liver - Plasma proteins" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Hepatocytes - Metabolism" 1 "HPA003825: AB_1078790" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (2.93e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-1)" "prognostic favorable (4.63e-5)" "unprognostic (6.97e-2)" "unprognostic (1.26e-2)" "unprognostic (3.96e-2)" "unprognostic (4.41e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (4.11e-2)" "unprognostic (3.69e-1)" "unprognostic (3.40e-6)" "unprognostic (6.48e-2)" F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 224.8;placenta: 473.0" "Group enriched" "Detected in many" 4 "Hofbauer cells: 791.5;Langerhans cells: 206.4;Macrophages: 321.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.3;myeloid DC: 179.8" "Group enriched" "Detected in many" 184 "dendritic cells: 179.8;granulocytes: 50.0;monocytes: 141.3" "Cancer enhanced" "Detected in some" "cervical cancer: 13.1;Leukemia: 20.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" "Blood coagulation" NA NA 1400000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Placenta - Pregnancy" "Cluster 8: Immune cells - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 12 "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" F13B FXIIIB ENSG00000143278 "Coagulation factor XIII B chain" P05160 1 197038741-197067260 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 210 "liver: 194.1" "Cell type enriched" "Detected in some" 16 "Hepatocytes: 59.1" "Cancer enriched" "Detected in single" 816 "liver cancer: 46.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003827, HPA052139" Supported "Secreted to blood" "Blood coagulation" NA NA 4700000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "HPA003827: AB_1078794, HPA052139: AB_2681744" "unprognostic (1.46e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.21e-2)" F2 ENSG00000180210 "Coagulation factor II, thrombin" P00734 11 46719196-46739506 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1310 "liver: 1180.6" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 841.1" "Cancer enriched" "Detected in some" 110 "liver cancer: 508.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "liver cancer: 64.3" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016780, HPA051476, HPA054698" Enhanced "Secreted to blood" "Blood coagulation" NA NA 108000000000 41000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 1 "CAB016780: , HPA051476: AB_2681498, HPA054698: AB_2682578" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "unprognostic (2.64e-2)" "unprognostic (1.85e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (2.23e-2)" "unprognostic (3.94e-2)" "unprognostic (5.79e-2)" "unprognostic (8.29e-2)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.75e-12)" "unprognostic (5.65e-3)" "unprognostic (5.80e-2)" "unprognostic (1.54e-3)" F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 673.7;Basal respiratory cells: 344.3;Club cells: 387.7;Exocrine glandular cells: 355.4;Ionocytes: 309.6;Peritubular cells: 505.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 655.6" "Kidney - Podocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 603000 "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" F5 ENSG00000198734 "Coagulation factor V" P12259 1 169511951-169586588 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 79.3;liver: 171.0;placenta: 45.4" "Group enriched" "Detected in many" 7 "Cholangiocytes: 95.4;Cytotrophoblasts: 83.4;Hepatocytes: 220.7;Syncytiotrophoblasts: 60.4" "Cancer enriched" "Detected in many" 7 "liver cancer: 69.6" "Region enriched" "Detected in all" 22 "choroid plexus: 306.3" "Group enriched" "Detected in some" 4 "classical monocyte: 4.1;eosinophil: 8.1;neutrophil: 7.0;T-reg: 6.2" "Group enriched" "Detected in many" 13 "granulocytes: 8.1;monocytes: 4.1;T-cells: 6.2" "Cancer enhanced" "Detected in many" "liver cancer: 17.9" "Breast - Adipocytes (Breast), Kidney - Podocytes, Liver - Hepatocytes, Lung - Neutrophil_2, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Group enriched" "Detected in many" 5 "basal ganglia: 2.7;hippocampal formation: 6.6;pons and medulla: 4.4;thalamus: 5.5" "Group enriched" "Detected in all" 7 "amygdala: 53.1;basal ganglia: 46.2;cerebral cortex: 89.3;hippocampal formation: 80.9;olfactory bulb: 37.0" HPA002036 Approved "Golgi apparatus" "Secreted to blood" "Blood coagulation" NA NA 7670000000 13000000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 11: Liver - Plasma proteins" "Cluster 36: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 62: Hepatocytes - Metabolism" "Golgi apparatus" "HPA002036: AB_1078787" "unprognostic (3.67e-2)" "unprognostic (2.77e-4)" "unprognostic (5.42e-2)" "unprognostic (2.56e-4)" "unprognostic (2.03e-1)" "unprognostic (2.39e-4)" "unprognostic (3.46e-3)" "unprognostic (9.25e-3)" "unprognostic (2.02e-1)" "unprognostic (8.99e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.15e-2)" "unprognostic (3.41e-1)" "unprognostic (4.31e-1)" F7 ENSG00000057593 "Coagulation factor VII" P08709 13 113105788-113120685 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "liver: 156.3" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 119.3" "Cancer enriched" "Detected in some" 17 "liver cancer: 41.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 3.0;liver cancer: 8.7" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA004826 Approved Mitochondria "Secreted to blood" "Blood coagulation" NA NA 351000000 1300000000 "Cluster 31: Liver - Plasma proteins" "Cluster 1: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 1 Mitochondria "HPA004826: AB_10602805" "unprognostic (2.06e-1)" "unprognostic (2.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.50e-3)" "unprognostic (3.81e-1)" "unprognostic (4.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.35e-3)" "unprognostic (3.36e-3)" "unprognostic (1.09e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" F8 "DXS1253E, F8C, FVIII, HEMA" ENSG00000185010 "Coagulation factor VIII" P00451 X 154835788-155026940 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Disease variant, FDA approved drug targets, Hemophilia, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 51.5" "Cell type enhanced" "Detected in many" "Adipocytes: 107.1;Endothelial cells: 203.3;Lymphatic endothelial cells: 132.0" "Cancer enhanced" "Detected in all" "renal cancer: 7.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB018777 Enhanced "Secreted to blood" "Blood coagulation" NA NA 25000000 "Cluster 33: Non-specific - ATP binding" "Cluster 30: Heart muscle - Heart development" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "CAB018777: AB_640320" "unprognostic (2.09e-1)" "unprognostic (5.66e-4)" "unprognostic (4.94e-2)" "unprognostic (8.32e-5)" "unprognostic (1.26e-1)" "unprognostic (5.05e-2)" "unprognostic (6.05e-2)" "unprognostic (8.27e-2)" "unprognostic (6.58e-2)" "unprognostic (1.68e-1)" "unprognostic (1.67e-2)" "unprognostic (5.58e-2)" "unprognostic (1.24e-2)" "unprognostic (2.16e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-2)" "unprognostic (4.44e-2)" F9 FIX ENSG00000101981 "Coagulation factor IX" P00740 X 139530739-139563459 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets, Hemophilia, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2448 "liver: 683.7" "Group enriched" "Detected in some" 12 "Hepatocytes: 519.8;Kupffer cells: 161.1" "Cancer enriched" "Detected in single" 1354 "liver cancer: 67.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" "Blood coagulation" NA NA 8200000000 "Cluster 31: Liver - Plasma proteins" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Hepatocytes - Metabolism" "prognostic favorable (6.69e-4)" FABP5 "E-FABP, KFABP, PA-FABP" ENSG00000164687 "Fatty acid binding protein 5" Q01469 8 81280536-81284777 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1805.2;esophagus: 3587.3;vagina: 2521.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3926.9;Basal squamous epithelial cells: 2822.4;Hofbauer cells: 2210.6;Squamous epithelial cells: 9957.6;Suprabasal keratinocytes: 7972.1" "Group enriched" "Detected in all" 4 "cervical cancer: 268.3;head and neck cancer: 288.8;urothelial cancer: 73.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017831, CAB040577, HPA051895" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Transport NA NA 14000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB017831: , CAB040577: , HPA051895: AB_2681654" "unprognostic (8.76e-2)" "unprognostic (7.28e-2)" "unprognostic (1.54e-2)" "unprognostic (9.04e-2)" "unprognostic (1.33e-3)" "unprognostic (1.37e-1)" "unprognostic (1.95e-3)" "unprognostic (4.03e-3)" "unprognostic (2.71e-1)" "unprognostic (3.13e-1)" "unprognostic (6.16e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (4.69e-10)" "unprognostic (1.99e-1)" "unprognostic (3.72e-1)" "unprognostic (1.61e-1)" "unprognostic (6.60e-2)" FABP6 "I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP" ENSG00000170231 "Fatty acid binding protein 6" P51161 5 160187367-160238735 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 85 "intestine: 4405.2" "Cell type enriched" "Detected in some" 65 "Proximal enterocytes: 68077.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 62.8" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 6.6" "HPA012601, CAB024713" Enhanced "Intracellular and membrane" Transport NA NA 890000 "Cluster 25: Small intestine - Absorption" "Cluster 44: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" "CAB024713: , HPA012601: AB_1848435" "unprognostic (3.03e-2)" "unprognostic (7.55e-2)" "unprognostic (1.27e-1)" "unprognostic (5.00e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (5.35e-7)" "unprognostic (3.05e-1)" "unprognostic (1.97e-1)" "unprognostic (2.41e-2)" "unprognostic (2.16e-1)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.35e-9)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (2.48e-1)" "unprognostic (1.85e-3)" FAM172A "C5orf21, DKFZP564D172, Toupee" ENSG00000113391 "Family with sequence similarity 172 member A" Q8WUF8 5 93617725-94111699 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 165.3;Excitatory neurons: 251.1;Inhibitory neurons: 285.2;Microglial cells: 217.4;Oligodendrocyte precursor cells: 248.6;Oligodendrocytes: 320.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012299, HPA045505" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" Other NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Neuronal - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 1 Nucleoplasm Cytosol "HPA012299: AB_1845724, HPA045505: AB_2679354" "unprognostic (1.12e-2)" "unprognostic (2.17e-1)" "unprognostic (3.10e-2)" "unprognostic (7.78e-2)" "unprognostic (2.03e-2)" "unprognostic (1.23e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-2)" "unprognostic (1.51e-1)" "unprognostic (1.57e-2)" "unprognostic (2.52e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.38e-1)" "unprognostic (6.56e-2)" "unprognostic (1.72e-2)" "unprognostic (1.03e-2)" FAM177A1 C14orf24 ENSG00000151327 "Family with sequence similarity 177 member A1" Q8N128 14 35045117-35116630 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 809.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053222, HPA055440" Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" "No annotated function" NA NA 170000 "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Vesicles Nucleoplasm "HPA053222: AB_2682083, HPA055440: AB_2682817" "unprognostic (6.86e-2)" "unprognostic (2.03e-1)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (1.91e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (4.64e-3)" "unprognostic (6.28e-2)" "unprognostic (7.79e-2)" "prognostic favorable (8.51e-5)" "unprognostic (1.12e-2)" "unprognostic (7.22e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (1.69e-1)" "unprognostic (8.28e-2)" "unprognostic (1.91e-1)" FAM180A "HWKM1940, UNQ1940" ENSG00000189320 "Family with sequence similarity 180 member A" Q6UWF9 7 135728348-135748813 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 15.5;heart muscle: 15.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.0;Fibroblasts: 15.9;Langerhans cells: 6.0;Melanocytes: 5.2;Mesothelial cells: 5.4;Ovarian stromal cells: 4.5;Pancreatic endocrine cells: 8.5;Peritubular cells: 4.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 6 "choroid plexus: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 8.8;Sarcoma: 21.6" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021224 Uncertain Approved Nucleoplasm "Secreted - unknown location" "No annotated function" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm "HPA021224: AB_1851352" "unprognostic (3.85e-2)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-2)" "unprognostic (1.97e-3)" "unprognostic (5.62e-2)" "unprognostic (7.55e-2)" "unprognostic (8.88e-4)" "unprognostic (3.14e-3)" "unprognostic (1.82e-1)" "unprognostic (4.35e-4)" "unprognostic (6.62e-4)" FAM180B LOC399888 ENSG00000196666 "Family with sequence similarity 180 member B" Q6P0A1 11 47586678-47589194 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "choroid plexus: 26.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 16.3;Langerhans cells: 7.2;Leydig cells: 2.4;Peritubular cells: 4.0" "Cancer enhanced" "Detected in some" "melanoma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enhanced" "Detected in many" "spinal cord: 7.7" HPA029408 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 15: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 53: Fibroblasts - ECM organization" 1 "HPA029408: AB_10601319" "unprognostic (1.28e-2)" "unprognostic (4.99e-3)" "unprognostic (7.48e-2)" "unprognostic (7.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.64e-2)" "unprognostic (1.21e-3)" "unprognostic (1.04e-1)" "unprognostic (2.69e-1)" "unprognostic (3.87e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-5)" "unprognostic (5.65e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" FAM20A DKFZp434F2322 ENSG00000108950 "FAM20A golgi associated secretory pathway pseudokinase" Q96MK3 17 68535113-68601367 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 49.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.8;Hepatocytes: 56.0;Hofbauer cells: 81.0;Late spermatids: 197.5;Serous glandular cells: 98.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Adipose subcutaneous - Adipose progenitor cells, Colon - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048964 Approved "Secreted in other tissues" Other NA NA 13000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "HPA048964: AB_2680575" "unprognostic (3.68e-2)" "unprognostic (3.14e-2)" "unprognostic (3.35e-2)" "unprognostic (4.49e-3)" "unprognostic (6.56e-2)" "unprognostic (5.29e-2)" "unprognostic (3.90e-3)" "unprognostic (2.39e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (9.16e-10)" "unprognostic (1.25e-3)" "unprognostic (1.06e-1)" "unprognostic (4.55e-2)" "unprognostic (2.39e-2)" FAM20C "DKFZp547D065, DMP4, G-CK, IMAGE:4942737" ENSG00000177706 "FAM20C golgi associated secretory pathway kinase" Q8IXL6 7 192571-260772 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" Biomineralization "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 78.7;Serous glandular cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 50.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019823 Supported "Nucleoplasm,Golgi apparatus" "Secreted in other tissues" Enzyme NA NA 240000000 "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 75: Serous glandular cells - Salivary secretion" 3 "Golgi apparatus" Nucleoplasm "HPA019823: AB_1848389" "unprognostic (1.94e-1)" "prognostic unfavorable (8.89e-4)" "unprognostic (3.15e-2)" "unprognostic (1.03e-2)" "unprognostic (3.33e-3)" "unprognostic (2.47e-2)" "unprognostic (7.86e-2)" "unprognostic (2.45e-3)" "unprognostic (3.35e-2)" "prognostic unfavorable (9.40e-6)" "unprognostic (1.97e-3)" "unprognostic (2.49e-1)" "unprognostic (3.08e-3)" "unprognostic (1.94e-2)" "unprognostic (3.92e-2)" "unprognostic (2.16e-2)" "unprognostic (3.83e-3)" FAM24A AC073585.4 ENSG00000203795 "Family with sequence similarity 24 member A" A6NFZ4 10 122910610-122913111 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 172 "testis: 17.1" "Cell type enriched" "Detected in some" 49 "Early spermatids: 458.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA052490 Supported "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 27: Breast cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" "HPA052490: AB_2681851" FAM24B "AC073585.2, MGC45962" ENSG00000213185 "Family with sequence similarity 24 member B" Q8N5W8 10 122849078-122879641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.6" "Group enriched" "Detected in many" 4 "Distal tubular cells: 83.0;Early spermatids: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Kidney - Intercalated cells, Testis - Early spermatids" HPA052490 Supported "Intracellular and membrane" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 28: Neuronal - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 18: Early spermatids - Unknown function" 2 "HPA052490: AB_2681851" "unprognostic (4.03e-2)" "unprognostic (4.27e-2)" "unprognostic (3.13e-3)" "unprognostic (8.40e-5)" "unprognostic (2.55e-2)" "unprognostic (3.31e-2)" "unprognostic (6.42e-7)" "unprognostic (2.99e-1)" "unprognostic (7.06e-3)" "unprognostic (3.00e-1)" "unprognostic (5.89e-2)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" "unprognostic (2.58e-1)" "unprognostic (9.23e-2)" "unprognostic (1.25e-1)" "unprognostic (8.81e-3)" FAM3A "2-19, DXS560S, XAP-7" ENSG00000071889 "FAM3 metabolism regulating signaling molecule A" P98173 X 154506159-154516242 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 113.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025016, HPA035268, HPA056991" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" "Secreted to blood" "No annotated function" Yes No 15000 "Cluster 41: Basophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 16: Intestinal goblet cells - Mucin production" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "CAB025016: , HPA035268: , HPA056991: AB_2683303" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.19e-2)" "unprognostic (4.73e-2)" "unprognostic (5.19e-2)" "unprognostic (2.54e-2)" "unprognostic (2.57e-2)" "unprognostic (2.53e-1)" "unprognostic (6.27e-2)" "unprognostic (3.42e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (2.74e-1)" "unprognostic (1.41e-1)" "unprognostic (4.04e-1)" "unprognostic (9.71e-2)" FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 138.6;pancreas: 206.1;salivary gland: 116.0;stomach 1: 111.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 311.2;Exocrine glandular cells: 293.7;Proximal enterocytes: 846.1;Serous glandular cells: 260.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Region enriched" "Detected in single" 9 "choroid plexus: 2.3" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cancer enhanced" "Detected in many" "breast cancer: 12.3;colorectal cancer: 8.6;lung cancer: 7.7" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells (progenitors), Liver - Cholangiocyte, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" Cytokine NA NA 2080000 250000 "Cluster 48: Stomach - Proteolysis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 3 Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" FAM3C "GS3876, ILEI" ENSG00000196937 "FAM3 metabolism regulating signaling molecule C" Q92520 7 121348878-121396364 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 303.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "memory B-cell: 22.6;naive B-cell: 20.1" "Lineage enriched" "Detected in many" 7 "B-cells: 22.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043376, HPA050548" Enhanced Enhanced "Golgi apparatus" "Secreted in other tissues" "Developmental protein" NA NA 48000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 45 "Golgi apparatus" "HPA043376: AB_2678452, HPA050548: AB_2681169" "unprognostic (9.44e-2)" "unprognostic (3.91e-1)" "unprognostic (1.75e-1)" "unprognostic (8.11e-3)" "unprognostic (1.26e-2)" "unprognostic (3.09e-3)" "unprognostic (3.38e-3)" "unprognostic (2.44e-1)" "unprognostic (2.95e-1)" "unprognostic (1.22e-2)" "unprognostic (2.15e-3)" "unprognostic (1.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.48e-1)" "unprognostic (9.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" FAM3D "EF7, OIT1" ENSG00000198643 "FAM3 metabolism regulating signaling molecule D" Q96BQ1 3 58633946-58666834 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 257.4;intestine: 472.8;salivary gland: 454.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 358.6;Distal enterocytes: 916.6;Enteroendocrine cells: 310.4;Intestinal goblet cells: 1087.5;Ionocytes: 340.2;Paneth cells: 568.5;Proximal enterocytes: 348.8;Serous glandular cells: 586.3;Undifferentiated cells: 430.5" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 151.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Lineage enhanced" "Detected in single" "granulocytes: 3.7" "Group enriched" "Detected in some" 6 "colorectal cancer: 29.2;Gastric cancer: 13.6" "Colon - Colon enterocytes, Pancreas - Ductal cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013844 Approved "Secreted to digestive system" "No annotated function" NA NA 15000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA013844: AB_2668897" "prognostic favorable (7.51e-4)" "unprognostic (1.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.67e-2)" "unprognostic (5.51e-2)" "prognostic favorable (1.89e-4)" "unprognostic (7.97e-2)" "unprognostic (6.54e-2)" "unprognostic (7.43e-2)" "unprognostic (5.48e-2)" "unprognostic (2.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.68e-2)" "unprognostic (1.64e-1)" "unprognostic (2.00e-1)" "unprognostic (6.97e-4)" "unprognostic (2.34e-2)" FAM78A "C9orf59, FLJ00024" ENSG00000126882 "Family with sequence similarity 78 member A" Q5JUQ0 9 131258076-131277365 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 60.5;testis: 31.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 44.7;Early spermatids: 63.4;Extravillous trophoblasts: 42.0;Late spermatids: 128.2;NK-cells: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Leukemia: 42.0;lymphoma: 25.8;Myeloma: 17.1" "Heart muscle - Cardiomyocytes, Liver - Kupffer cells, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021472, HPA023914" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 11: Late spermatids - Unknown function" 2 "Nucleoplasm, Vesicles" "HPA021472: AB_1848411, HPA023914: AB_1848412" "unprognostic (5.16e-2)" "prognostic favorable (3.67e-4)" "unprognostic (3.65e-2)" "unprognostic (2.07e-2)" "unprognostic (2.71e-1)" "prognostic favorable (2.00e-4)" "unprognostic (3.24e-1)" "unprognostic (5.49e-2)" "unprognostic (1.46e-2)" "unprognostic (5.83e-1)" "unprognostic (5.84e-2)" "unprognostic (6.79e-2)" "unprognostic (1.59e-3)" "unprognostic (2.61e-3)" "unprognostic (7.42e-2)" "unprognostic (2.61e-2)" "unprognostic (2.39e-1)" FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 30.5;smooth muscle: 25.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 63.7;Fibroblasts: 47.2;Microglial cells: 17.0;Muller glia cells: 45.5;Pancreatic endocrine cells: 32.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 27.0" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 4.0;hippocampal formation: 3.1" HPA059739 Uncertain "Secreted to blood" "Cell adhesion" NA NA 108000000 56000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88953813-89029605 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 66.0;Secretory cells: 76.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 101.1" "Group enriched" "Detected in all" 5 "granulocytes: 101.1;T-cells: 90.6" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 11900000 420000 "Cluster 35: Neutrophils - Protein binding" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 48: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 8 "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.6" "Group enriched" "Detected in some" 7 "NK-cells: 71.7;T-cells: 26.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.2" "Group enriched" "Detected in many" 9 "NK-cells: 41.6;T-cells: 58.2" "Cancer enriched" "Detected in single" 4 "colorectal cancer: 1.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" Cytokine NA NA 73600 "Cluster 15: NK-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 19: NK-cells - Adaptive immune response" 28 "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" FAT1 "CDHF7, CDHR8, FAT" ENSG00000083857 "FAT atypical cadherin 1" Q14517 4 186587794-186726722 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 84.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 111.6;Salivary duct cells: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "HPA001869, HPA023882" Enhanced "Intracellular and membrane" "Cell adhesion" NA NA 4600000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "HPA001869: AB_1078818, HPA023882: AB_1848429" "unprognostic (1.98e-1)" "unprognostic (4.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.86e-1)" "unprognostic (1.53e-2)" "unprognostic (5.82e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.15e-3)" "unprognostic (6.80e-2)" "unprognostic (3.57e-2)" "unprognostic (8.03e-3)" "unprognostic (9.41e-2)" "unprognostic (6.25e-3)" "unprognostic (4.27e-2)" FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1826.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 636.6;Endometrial stromal cells: 611.2;Extravillous trophoblasts: 720.8;Fibroblasts: 1354.1;Syncytiotrophoblasts: 1303.4" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Region enriched" "Detected in all" 13 "choroid plexus: 1731.1" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" Other NA NA 21000000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 283.2" "Cell type enhanced" "Detected in many" "Adipocytes: 87.2;Endometrial stromal cells: 83.8;Fibroblasts: 408.9;Leydig cells: 174.8;Peritubular cells: 214.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 92.6" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA 35000000 "Cluster 18: Non-specific - Translation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 7 "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Fibroblasts: 215.1;Leydig cells: 615.0;Peritubular cells: 773.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.7" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 12000000 "Cluster 41: Basophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 11 "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 14.8;Inhibitory neurons: 29.6;Melanocytes: 22.3;Oocytes: 83.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.5;naive CD4 T-cell: 29.6;T-reg: 36.6" "Lineage enriched" "Detected in many" 35 "T-cells: 36.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 17.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" "Cell adhesion" NA NA 310000 "Cluster 31: T-cells - T-cell receptor" "Cluster 16: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" FBN1 "FBN, MASS, MFS1, OCTD, SGS, WMS" ENSG00000166147 "Fibrillin 1" P35555 15 48408313-48645721 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Heparin-binding, Hormone" "Aortic aneurysm, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 51.1;placenta: 63.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 127.4;Fibroblasts: 446.6;Inhibitory neurons: 118.4;Leydig cells: 235.6;Oligodendrocytes: 203.5;Peritubular cells: 227.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 71.3" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002670, HPA017759, HPA021057, CAB058696, CAB068188, CAB080202" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" Hormone NA NA 520000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 7 "Golgi apparatus" "Plasma membrane" "CAB002670: , CAB058696: AB_2665596, CAB068188: AB_2665597, CAB080202: , HPA017759: AB_1848584, HPA021057: AB_1848586" "unprognostic (3.97e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.51e-1)" "unprognostic (9.49e-2)" "unprognostic (2.00e-2)" "unprognostic (4.79e-2)" "unprognostic (7.82e-2)" "unprognostic (1.50e-2)" "unprognostic (2.78e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (7.44e-5)" "prognostic unfavorable (6.57e-4)" "unprognostic (1.25e-2)" "unprognostic (8.69e-3)" "prognostic unfavorable (5.11e-4)" FBN2 "CCA, DA9" ENSG00000138829 "Fibrillin 2" P35556 5 128257909-128659185 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "placenta: 65.0" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 292.9;Syncytiotrophoblasts: 154.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Lineage enriched" "Detected in single" 6 "monocytes: 2.2" "Cancer enhanced" "Detected in many" "Sarcoma: 46.8" "Testis - Early spermatids" "Region enhanced" "Detected in single" "olfactory bulb: 2.0" "Low region specificity" "Detected in many" "HPA012853, CAB026401" Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 11000000 "Cluster 58: Placenta - Pregnancy" "Cluster 3: Choroid plexus - Cilium" "Cluster 3: Rhabdoid - Membrane components" "Cluster 24: Cytotrophoblasts - Mitochondria" "CAB026401: , HPA012853: AB_1848588" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (7.29e-3)" "unprognostic (1.79e-3)" "unprognostic (6.74e-2)" "unprognostic (2.33e-1)" "unprognostic (4.92e-3)" "unprognostic (9.41e-2)" "unprognostic (1.06e-2)" "unprognostic (4.66e-1)" "unprognostic (1.12e-1)" "unprognostic (8.69e-2)" "unprognostic (8.60e-5)" "unprognostic (1.04e-2)" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (7.41e-5)" FBN3 KIAA1776 ENSG00000142449 "Fibrillin 3" Q75N90 19 8065402-8149592 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.3;salivary gland: 3.9" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 16.0" "Cancer enhanced" "Detected in many" "testis cancer: 8.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.9;testis cancer: 4.2" "Kidney - Intercalated cells" "Low region specificity" "Detected in single" HPA049482 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 2400000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "HPA049482: AB_2680786" "unprognostic (9.66e-3)" "unprognostic (5.15e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (4.14e-2)" "unprognostic (5.14e-3)" "unprognostic (6.26e-2)" "unprognostic (4.10e-3)" "unprognostic (3.17e-2)" "unprognostic (8.94e-2)" "unprognostic (4.61e-2)" "unprognostic (1.53e-1)" "unprognostic (2.76e-2)" "unprognostic (1.34e-2)" "unprognostic (2.57e-1)" "unprognostic (1.17e-2)" "unprognostic (3.17e-1)" FCAR "CD89, FcalphaR, FcalphaRI" ENSG00000186431 "Fc alpha receptor" P24071 19 54874235-54891420 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "IgA-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 25.9;lung: 10.2;lymphoid tissue: 13.1" "Group enriched" "Detected in some" 5 "Kupffer cells: 13.9;Macrophages: 20.4;monocytes: 47.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "classical monocyte: 1.3;neutrophil: 4.1" "Group enriched" "Detected in many" 27 "granulocytes: 4.1;monocytes: 1.3" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" HPA014050 Approved Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "HPA014050: AB_1846338" "unprognostic (1.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (4.71e-3)" "unprognostic (3.46e-1)" "unprognostic (2.02e-1)" "unprognostic (7.99e-2)" "unprognostic (1.54e-2)" "unprognostic (1.59e-2)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (7.05e-2)" "unprognostic (4.19e-6)" "unprognostic (9.23e-2)" "unprognostic (8.10e-3)" "unprognostic (8.04e-3)" "unprognostic (9.81e-2)" FCER2 "CD23, CD23A, CLEC4J, FCE2, FcepsilonRII, FCErII" ENSG00000104921 "Fc epsilon receptor II" P06734 19 7688758-7702146 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgE-binding protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 41.0" "Cell type enriched" "Detected in some" 16 "B-cells: 141.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.1" "Region enhanced" "Detected in single" "cerebral cortex: 2.8" "Group enriched" "Detected in many" 24 "memory B-cell: 201.7;naive B-cell: 497.3" "Lineage enriched" "Detected in many" 34 "B-cells: 497.3" "Group enriched" "Detected in some" 16 "Leukemia: 49.4;lymphoma: 34.1;Myeloma: 41.1" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002624, HPA008928, HPA067430" Enhanced "Secreted to blood" Receptor NA NA 240000 "Cluster 18: Non-specific - Translation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 1 "CAB002624: , HPA008928: AB_1846285, HPA067430: " "unprognostic (3.20e-4)" "unprognostic (1.87e-3)" "unprognostic (1.95e-2)" "unprognostic (2.44e-2)" "unprognostic (4.77e-2)" "unprognostic (1.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.89e-3)" "unprognostic (2.71e-1)" "unprognostic (1.88e-1)" "unprognostic (2.04e-2)" "unprognostic (8.55e-2)" "unprognostic (2.46e-4)" "unprognostic (2.99e-1)" "unprognostic (1.80e-1)" "unprognostic (4.89e-2)" "unprognostic (5.17e-2)" FCGBP "FC(GAMMA)BP, FcgammaBP" ENSG00000275395 "Fc gamma binding protein" 19 39863323-39934626 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 201.2;salivary gland: 82.9;thyroid gland: 96.9" "Cell type enriched" "Detected in many" 22 "Intestinal goblet cells: 10673.4" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Gastric cancer: 12.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" FCGR3A "CD16, CD16a, FCG3, FcgammaRIIIa, FCGR3, FcGRIIIA" ENSG00000203747 "Fc gamma receptor IIIa" P08637 1 161541759-161550968 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 202.0;lymphoid tissue: 294.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 240.5;Kupffer cells: 656.2;Macrophages: 303.8;monocytes: 1050.2;NK-cells: 597.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1806.3;non-classical monocyte: 4107.1" "Lineage enriched" "Detected in all" 6 "monocytes: 4107.1" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "CAB032435, HPA055431" Supported "Secreted to blood" Receptor NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" FCGR3B "CD16, CD16b, FCG3, FcgammaRIIIb, FCGR3, FcRIIIb" ENSG00000162747 "Fc gamma receptor IIIb" O75015 1 161623196-161631963 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.5;lymphoid tissue: 79.0" "Cell type enriched" "Detected in some" 7 "Serous glandular cells: 28.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 6 "cerebral cortex: 11.0;pons: 4.2" "Immune cell enriched" "Detected in many" 356 "neutrophil: 6077.6" "Lineage enriched" "Detected in many" 356 "granulocytes: 6077.6" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Secreted to blood" Receptor NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" "unprognostic (1.60e-1)" "unprognostic (1.36e-1)" "unprognostic (1.59e-3)" "unprognostic (4.16e-2)" "unprognostic (1.15e-1)" "unprognostic (6.52e-2)" "unprognostic (3.97e-2)" "unprognostic (6.96e-3)" "unprognostic (2.53e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (8.67e-2)" "unprognostic (5.16e-2)" "unprognostic (1.35e-1)" "unprognostic (8.37e-3)" "unprognostic (2.28e-1)" "unprognostic (9.24e-2)" FCMR "FAIM3, FcmuR, TOSO" ENSG00000162894 "Fc mu receptor" O60667 1 206903317-206923247 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 63.7;lymphoid tissue: 175.4" "Group enriched" "Detected in many" 5 "B-cells: 334.0;NK-cells: 96.0;T-cells: 108.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 10 "Leukemia: 23.9;lymphoma: 55.8;Myeloma: 45.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003910 Approved Approved "Plasma membrane,Focal adhesion sites" "Secreted to blood" Immunity NA NA 5500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "Plasma membrane, Focal adhesion sites" "HPA003910: AB_1078798" "prognostic favorable (4.23e-4)" "unprognostic (1.16e-3)" "unprognostic (7.48e-2)" "unprognostic (3.06e-3)" "unprognostic (2.04e-1)" "unprognostic (2.69e-3)" "unprognostic (1.15e-1)" "unprognostic (4.85e-3)" "unprognostic (1.03e-1)" "unprognostic (3.97e-1)" "unprognostic (3.23e-2)" "unprognostic (2.01e-1)" "unprognostic (8.15e-3)" "unprognostic (8.06e-2)" "unprognostic (2.12e-2)" "unprognostic (3.74e-2)" "unprognostic (5.05e-3)" FCN1 FCNM ENSG00000085265 "Ficolin 1" O00602 9 134903232-134917912 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 157.1;lung: 41.8;lymphoid tissue: 86.0" "Group enriched" "Detected in many" 6 "Hofbauer cells: 754.4;Kupffer cells: 531.0;Macrophages: 490.5;monocytes: 1059.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1694.0;intermediate monocyte: 1189.2" "Lineage enhanced" "Detected in all" "monocytes: 1694.0" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.1" "Adipose visceral - Neutrophils, Lung - Neutrophil_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000685, HPA001295, CAB016760" Enhanced "Secreted to blood" Immunity NA NA 1060000000 36000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "CAB016760: , HPA000685: AB_1078840, HPA001295: AB_1078842" "unprognostic (1.57e-2)" "unprognostic (2.23e-1)" "unprognostic (1.14e-3)" "unprognostic (1.34e-1)" "unprognostic (9.91e-2)" "unprognostic (1.62e-3)" "unprognostic (3.66e-3)" "unprognostic (2.21e-1)" "unprognostic (1.14e-1)" "unprognostic (5.59e-2)" "unprognostic (2.49e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.73e-2)" "unprognostic (5.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.28e-1)" FCN2 "EBP-37, FCNL, ficolin-2, P35" ENSG00000160339 "Ficolin 2" Q15485 9 134880810-134887523 "Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 96.6" "Group enriched" "Detected in some" 9 "Endothelial cells: 71.9;Fibroblasts: 194.2;Kupffer cells: 75.4" "Group enriched" "Detected in some" 8 "breast cancer: 1.0;liver cancer: 2.0;prostate cancer: 1.1;renal cancer: 0.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5;intermediate monocyte: 4.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells" "Region enriched" "Detected in some" 24 "spinal cord: 51.0" "Secreted to blood" Immunity NA NA 8100000000 1400000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-4)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" "unprognostic (3.81e-1)" "unprognostic (2.82e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" "unprognostic (1.05e-1)" "unprognostic (3.07e-1)" FCN3 "FCNH, HAKA1" ENSG00000142748 "Ficolin 3" O75636 1 27369110-27374824 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "liver: 270.1;lung: 702.7" "Group enriched" "Detected in some" 5 "Endothelial cells: 509.8;Fibroblasts: 450.4;Kupffer cells: 220.6" "Cancer enhanced" "Detected in many" "renal cancer: 7.6" "Region enriched" "Detected in all" 8 "choroid plexus: 20.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Liver - Sinusoid Endothelial cells, Testis - Endothelial cells" CAB025945 Approved "Secreted to blood" Immunity NA NA 22800000000 14000000000 "Cluster 11: Liver - Plasma proteins" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "CAB025945: " "unprognostic (1.59e-1)" "unprognostic (5.25e-2)" "unprognostic (1.55e-2)" "unprognostic (8.27e-2)" "unprognostic (1.45e-3)" "unprognostic (1.27e-2)" "unprognostic (1.87e-3)" "unprognostic (1.21e-1)" "unprognostic (6.28e-4)" "unprognostic (7.07e-2)" "unprognostic (2.86e-2)" "unprognostic (3.23e-2)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.02e-1)" "unprognostic (6.97e-2)" "unprognostic (1.61e-2)" FCRL5 "BXMAS1, CD307e, FCRH5, IRTA2" ENSG00000143297 "Fc receptor like 5" Q96RD9 1 157513377-157552515 "CD markers, Disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 35.4" "Group enriched" "Detected in some" 9 "B-cells: 83.7;Early spermatids: 68.8;Plasma cells: 249.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "memory B-cell: 13.0;naive B-cell: 14.2" "Lineage enriched" "Detected in single" 17 "B-cells: 14.2" "Group enriched" "Detected in some" 12 "lymphoma: 20.4;Myeloma: 7.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Receptor NA NA 169000000 65000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" 2 "unprognostic (1.30e-3)" "unprognostic (3.51e-2)" "unprognostic (7.59e-3)" "unprognostic (1.57e-2)" "unprognostic (9.41e-3)" "unprognostic (4.32e-5)" "unprognostic (2.61e-2)" "unprognostic (6.93e-2)" "unprognostic (7.40e-2)" "unprognostic (7.66e-3)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (9.51e-10)" "unprognostic (1.20e-1)" "unprognostic (4.40e-1)" "unprognostic (8.99e-2)" "unprognostic (2.78e-1)" FCRLA "FCRL, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRLM1, FCRLX, FREB, MGC4595" ENSG00000132185 "Fc receptor like A" Q7L513 1 161706972-161714352 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 95.7" "Group enriched" "Detected in some" 4 "B-cells: 129.6;Melanocytes: 34.4" "Cancer enriched" "Detected in many" 21 "melanoma: 38.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 369.4;naive B-cell: 342.8" "Lineage enriched" "Detected in many" 10 "B-cells: 369.4" "Cancer enriched" "Detected in some" 5 "lymphoma: 220.7" "Skin - Melanocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB016545 Enhanced "Intracellular and membrane" Other NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "CAB016545: AB_2247037" "unprognostic (5.46e-4)" "unprognostic (7.19e-2)" "unprognostic (3.69e-3)" "unprognostic (4.75e-4)" "unprognostic (4.69e-2)" "unprognostic (1.48e-4)" "unprognostic (1.45e-2)" "unprognostic (4.15e-3)" "unprognostic (8.66e-2)" "unprognostic (3.58e-4)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (6.84e-5)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (1.56e-1)" "unprognostic (2.08e-2)" FCRLB "FCRL2, FCRLM2, FCRLY, FLJ31052, FREB-2" ENSG00000162746 "Fc receptor like B" Q6BAA4 1 161721544-161728143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 8.1;Erythroid cells: 7.4;NK-cells: 7.5;Proximal tubular cells: 7.8;Secretory cells: 6.9;Sertoli cells: 8.2" "Cancer enhanced" "Detected in many" "urothelial cancer: 7.8" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 17 "lymphoma: 25.9" "Not detected" "Not detected" "Not detected" "Not detected" CAB026139 Uncertain Supported Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 19: NK-cells - Adaptive immune response" Cytosol "CAB026139: " "unprognostic (1.87e-1)" "unprognostic (1.20e-4)" "unprognostic (5.77e-3)" "unprognostic (7.49e-3)" "unprognostic (1.73e-3)" "unprognostic (2.95e-1)" "unprognostic (2.98e-2)" "unprognostic (1.18e-3)" "unprognostic (1.89e-1)" "unprognostic (3.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.60e-1)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.27e-1)" "unprognostic (9.92e-3)" "unprognostic (3.14e-2)" FDCSP "C4orf7, FDC-SP" ENSG00000181617 "Follicular dendritic cell secreted protein" Q8NFU4 4 70226124-70235252 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "lymphoid tissue: 3158.9;salivary gland: 6415.4" "Cell type enriched" "Detected in some" 5 "Mucus glandular cells: 3349.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 336.0" "Region enhanced" "Detected in single" "midbrain: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 85.9;Rhabdoid: 24.2" "Not detected" "Not detected" "HPA014326, CAB014890" Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 3: Choroid plexus - Cilium" "Cluster 1: Neuronal - Visual perception" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "CAB014890: , HPA014326: AB_1845719" "unprognostic (1.26e-3)" "unprognostic (2.32e-1)" "unprognostic (8.73e-3)" "unprognostic (9.62e-2)" "prognostic favorable (2.38e-4)" "unprognostic (5.99e-3)" "prognostic favorable (1.32e-4)" "unprognostic (2.04e-1)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.79e-1)" "unprognostic (1.96e-1)" "unprognostic (3.68e-2)" "unprognostic (2.80e-1)" "unprognostic (7.83e-2)" FETUB ENSG00000090512 "Fetuin B" Q9UGM5 3 186635969-186653141 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 227.3" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 46.2" "Cancer enriched" "Detected in some" 12 "liver cancer: 44.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035132, HPA035133" Supported Approved Vesicles "Secreted to blood" "Enzyme inhibitor" NA NA 47500000000 3600000000 "Cluster 83: Liver - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 43: Hepatocytes - Metabolism" 6 Vesicles "HPA035132: AB_10601650, HPA035133: " "unprognostic (9.01e-2)" "unprognostic (1.95e-1)" "unprognostic (4.62e-1)" "unprognostic (8.74e-2)" "unprognostic (6.28e-3)" "unprognostic (1.24e-2)" "unprognostic (7.55e-2)" "unprognostic (9.78e-2)" "unprognostic (1.73e-2)" "unprognostic (9.18e-2)" "unprognostic (1.79e-1)" "unprognostic (8.39e-2)" FGA ENSG00000171560 "Fibrinogen alpha chain" P02671 4 154583126-154590742 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 386 "liver: 17848.7" "Cell type enriched" "Detected in many" 30 "Hepatocytes: 13631.3" "Cancer enriched" "Detected in many" 43 "liver cancer: 2431.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "liver cancer: 180.5" "Liver - Hepatocytes, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "CAB016776, HPA051370, HPA064755" Supported Enhanced "Endoplasmic reticulum" "Secreted to blood" "Blood coagulation" NA NA 407000000 140000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 3 "Endoplasmic reticulum" "CAB016776: , HPA051370: AB_2681458, HPA064755: AB_2685345" "unprognostic (5.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.29e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.23e-6)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" FGB ENSG00000171564 "Fibrinogen beta chain" P02675 4 154563011-154572807 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 372 "liver: 17393.5" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 15989.7" "Cancer enriched" "Detected in many" 42 "liver cancer: 2262.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "liver cancer: 219.4" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001900, HPA001901, CAB008624" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to blood" "Blood coagulation" NA NA 110000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 1 "Endoplasmic reticulum" "CAB008624: AB_1615610, HPA001900: AB_1078865, HPA001901: AB_1078864" "unprognostic (1.16e-1)" "unprognostic (3.89e-2)" "unprognostic (4.65e-2)" "unprognostic (3.44e-1)" "unprognostic (2.20e-3)" "unprognostic (1.42e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.48e-2)" "unprognostic (7.91e-2)" FGF1 "AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-alpha, FGFA, GLIO703, HBGF1" ENSG00000113578 "Fibroblast growth factor 1" P05230 5 142592178-142698070 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 290.8" "Cell type enhanced" "Detected in many" "Astrocytes: 71.2;Breast myoepithelial cells: 29.1;Cardiomyocytes: 70.6;Muller glia cells: 66.4;Oligodendrocytes: 111.5" "Cancer enriched" "Detected in many" 12 "glioma: 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003265, CAB017519" Enhanced Supported Nucleoplasm "Secreted in other tissues" "Growth factor" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 4 Nucleoplasm "CAB017519: AB_629473, HPA003265: AB_1848522" "unprognostic (1.25e-2)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (3.41e-3)" "unprognostic (2.55e-2)" "unprognostic (3.52e-1)" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.63e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.54e-1)" "prognostic favorable (2.59e-5)" "unprognostic (3.72e-4)" "unprognostic (2.49e-1)" "prognostic favorable (3.45e-5)" "unprognostic (3.01e-4)" FGF10 ENSG00000070193 "Fibroblast growth factor 10" O15520 5 44300247-44389706 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant, Ectodermal dysplasia, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 53.0;Fibroblasts: 53.2;Leydig cells: 24.6;Ovarian stromal cells: 20.8;Peritubular cells: 32.7" "Cancer enriched" "Detected in some" 6 "breast cancer: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gastric cancer: 3.2;Neuroblastoma: 5.4;Sarcoma: 1.4" "Kidney - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB010315 Uncertain "Secreted in other tissues" "Growth factor" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 3 "CAB010315: AB_2262731" "unprognostic (1.40e-1)" "unprognostic (1.25e-1)" "unprognostic (8.54e-2)" "unprognostic (1.08e-1)" "unprognostic (3.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.54e-2)" "unprognostic (4.06e-3)" "unprognostic (2.72e-2)" "unprognostic (6.73e-2)" "unprognostic (5.59e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-2)" "unprognostic (1.11e-2)" "unprognostic (2.14e-2)" "unprognostic (5.23e-4)" FGF16 MF4 ENSG00000196468 "Fibroblast growth factor 16" O43320 X 77447389-77457278 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "choroid plexus: 4.3" "Cell type enhanced" "Detected in single" "Fibroblasts: 1.3" "Not detected" "Not detected" "Region enhanced" "Detected in some" "choroid plexus: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Sarcoma: 1.4" "Thyroid - Fibroblasts" "Group enriched" "Detected in some" 6 "basal ganglia: 3.6;hippocampal formation: 2.0;olfactory bulb: 6.7" "Not detected" "Not detected" "Secreted in other tissues" "Growth factor" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 6 "unprognostic (4.01e-2)" "unprognostic (5.30e-2)" "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.31e-1)" "unprognostic (6.57e-2)" "unprognostic (1.49e-2)" FGF17 FGF-13 ENSG00000158815 "Fibroblast growth factor 17" O60258 8 22042398-22048809 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "brain: 72.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.0;Cone photoreceptor cells: 8.5;Excitatory neurons: 10.3;Granulosa cells: 3.7;Horizontal cells: 6.9;Inhibitory neurons: 12.5" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6;testis cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "basal ganglia: 2.1" "Low region specificity" "Detected in some" HPA052600 Uncertain "Secreted in brain" "Growth factor" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA052600: AB_2681881" "unprognostic (3.45e-2)" "unprognostic (1.64e-2)" "unprognostic (3.03e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (3.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (5.65e-2)" "unprognostic (1.34e-1)" "unprognostic (7.92e-5)" "unprognostic (6.85e-2)" "unprognostic (2.58e-4)" "unprognostic (6.55e-3)" "unprognostic (7.18e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-3)" FGF18 "FGF-18, ZFGF5" ENSG00000156427 "Fibroblast growth factor 18" O76093 5 171419647-171457626 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 15.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 22.6;Cardiomyocytes: 38.0;Glandular and luminal cells: 25.0;Mesothelial cells: 11.8;Secretory cells: 18.9" "Group enriched" "Detected in many" 6 "endometrial cancer: 19.0;ovarian cancer: 21.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ovarian cancer: 35.7;Uterine cancer: 29.3" "Low region specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.1" HPA018795 Uncertain "Secreted in other tissues" "Growth factor" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Non-specific - Transcription" "HPA018795: AB_1848523" "unprognostic (3.01e-1)" "unprognostic (2.38e-2)" "unprognostic (1.23e-1)" "unprognostic (3.66e-3)" "unprognostic (6.62e-3)" "unprognostic (1.50e-1)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-3)" "unprognostic (3.65e-2)" "unprognostic (3.18e-2)" "unprognostic (2.29e-1)" "unprognostic (1.37e-8)" "unprognostic (7.33e-2)" "unprognostic (2.58e-1)" "unprognostic (3.19e-1)" "unprognostic (2.76e-2)" FGF19 ENSG00000162344 "Fibroblast growth factor 19" O95750 11 69698238-69704022 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "gallbladder: 229.2" "Group enriched" "Detected in some" 5 "Cholangiocytes: 34.3;Ductal cells: 14.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 31.1;Gastric cancer: 26.0" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA036082 Approved "Secreted to blood" "Growth factor" NA NA 133000 "Cluster 62: Connective tissue - ECM organization" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "HPA036082: AB_10669665" "unprognostic (7.46e-3)" "unprognostic (2.43e-3)" "unprognostic (5.52e-3)" "unprognostic (1.22e-1)" "unprognostic (4.68e-3)" "unprognostic (6.45e-2)" "unprognostic (5.72e-3)" "unprognostic (2.26e-1)" "unprognostic (6.39e-3)" "unprognostic (1.66e-2)" "unprognostic (8.82e-3)" FGF2 FGFB ENSG00000138685 "Fibroblast growth factor 2" P09038 4 122826682-122898236 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 33.5;Astrocytes: 105.3;Endometrial stromal cells: 38.6;Oligodendrocyte precursor cells: 39.6;Schwann cells: 56.0;Secretory cells: 37.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000125, HPA065502" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Secreted in other tissues" "Growth factor" NA NA 92500 "Cluster 64: Neuronal - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 5 "Nucleoplasm, Nuclear bodies" "CAB000125: , HPA065502: " "unprognostic (1.53e-2)" "unprognostic (3.12e-1)" "unprognostic (1.08e-1)" "unprognostic (7.42e-2)" "unprognostic (2.10e-1)" "unprognostic (3.33e-1)" "unprognostic (6.98e-2)" "unprognostic (1.25e-1)" "unprognostic (2.82e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (9.85e-4)" "unprognostic (3.37e-1)" "unprognostic (4.61e-3)" "unprognostic (2.36e-1)" "unprognostic (1.81e-1)" "unprognostic (4.45e-2)" "unprognostic (3.45e-3)" FGF20 ENSG00000078579 "Fibroblast growth factor 20" Q9NP95 8 16992181-17002345 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.8" "Cell type enriched" "Detected in some" 5 "Microglial cells: 8.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 17.9;Rhabdoid: 5.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 2.5" "Secreted in other tissues" "Growth factor" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Macrophages - Innate immune response" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (5.57e-3)" "unprognostic (3.95e-2)" "unprognostic (1.59e-3)" "unprognostic (1.40e-2)" "unprognostic (1.94e-1)" "unprognostic (2.65e-2)" "unprognostic (9.32e-2)" "unprognostic (9.95e-2)" "unprognostic (3.92e-1)" "unprognostic (4.08e-2)" FGF21 ENSG00000105550 "Fibroblast growth factor 21" Q9NSA1 19 48755524-48758333 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 107 "liver: 82.1" "Group enriched" "Detected in some" 38 "Cholangiocytes: 1.9;Hepatocytes: 6.5" "Cancer enriched" "Detected in single" 315 "liver cancer: 33.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 1.6;Rhabdoid: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061286 Supported "Secreted to blood" "Growth factor" NA NA 254000 73000 "Cluster 31: Liver - Plasma proteins" "Cluster 13: Non-specific - Mixed function" "Cluster 43: Hepatocytes - Metabolism" 6 "HPA061286: AB_2684466" "unprognostic (1.64e-2)" "unprognostic (3.62e-1)" "unprognostic (3.21e-2)" "unprognostic (3.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.85e-2)" FGF22 ENSG00000070388 "Fibroblast growth factor 22" Q9HCT0 19 639879-644373 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.6;skin 1: 13.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.5;Horizontal cells: 13.2;Ovarian stromal cells: 9.0;Rod photoreceptor cells: 6.5;Syncytiotrophoblasts: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" "Growth factor" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 37: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (2.84e-3)" "unprognostic (1.04e-2)" "unprognostic (1.17e-1)" "unprognostic (5.25e-4)" "unprognostic (1.16e-1)" "unprognostic (3.66e-3)" "unprognostic (2.85e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-4)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (3.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.31e-1)" "unprognostic (8.36e-2)" FGF23 ENSG00000118972 "Fibroblast growth factor 23" Q9GZV9 12 4368227-4379712 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" Differentiation "Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 4.8;liver: 4.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.4;Cone photoreceptor cells: 3.4;Early spermatids: 8.8;Endothelial cells: 2.6;Mucus glandular cells: 2.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "cerebral cortex: 105.3;choroid plexus: 69.3;midbrain: 27.6" "Immune cell enhanced" "Detected in all" "basophil: 9.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" "Growth factor" NA NA 56800 "Cluster 35: Neutrophils - Protein binding" "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "unprognostic (1.31e-1)" "unprognostic (2.18e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-1)" FGF3 "HBGF-3, INT2" ENSG00000186895 "Fibroblast growth factor 3" P11487 11 69809968-69819416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 133 "brain: 13.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.4" "Region enriched" "Detected in some" 6 "cerebellum: 7.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "cervical cancer: 21.5" "Region enhanced" "Detected in some" "basal ganglia: 3.1" "Not detected" "Not detected" HPA012692 Enhanced "Secreted in brain" "Growth factor" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 32: Non-specific - Cell proliferation" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA012692: AB_1848526" "unprognostic (6.42e-3)" "unprognostic (7.82e-2)" "unprognostic (1.89e-1)" "unprognostic (3.61e-1)" "unprognostic (7.75e-2)" FGF4 "HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF" ENSG00000075388 "Fibroblast growth factor 4" P08620 11 69771022-69775341 "Cancer-related genes, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 3.3;Late spermatids: 1.5;Spermatocytes: 1.3" "Cancer enriched" "Detected in some" 5 "testis cancer: 13.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 1.4;Gastric cancer: 3.3;liver cancer: 2.1;testis cancer: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA011209 Uncertain "Secreted in other tissues" "Growth factor" NA NA 326000 "Cluster 32: Non-specific - Cell proliferation" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA011209: AB_1848527" "unprognostic (1.47e-2)" "unprognostic (6.22e-2)" "unprognostic (7.77e-2)" "unprognostic (8.56e-2)" FGF5 ENSG00000138675 "Fibroblast growth factor 5" P12034 4 80266639-80336680 "Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.1;gallbladder: 2.7;intestine: 1.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.1;Melanocytes: 1.7;Microglial cells: 1.8;Proximal tubular cells: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 24.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 19.3" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted in brain" "Growth factor" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (8.49e-4)" "unprognostic (1.10e-1)" "unprognostic (2.91e-1)" "unprognostic (2.80e-3)" "unprognostic (6.87e-4)" "unprognostic (2.53e-1)" "unprognostic (1.69e-1)" "unprognostic (3.57e-3)" "unprognostic (1.17e-2)" "unprognostic (3.33e-16)" "unprognostic (3.02e-3)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" FGF6 ENSG00000111241 "Fibroblast growth factor 6" P10767 12 4428155-4445815 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "skeletal muscle: 13.3;tongue: 9.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Leukemia: 3.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Growth factor" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 36: Late spermatids - Unknown function" 1 "unprognostic (4.29e-2)" FGF7 KGF ENSG00000140285 "Fibroblast growth factor 7" P21781 15 49423237-49488775 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 61.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 61.2;Distal tubular cells: 46.1;Endometrial stromal cells: 41.1;Fibroblasts: 177.0;Leydig cells: 74.9;Ovarian stromal cells: 60.1;Smooth muscle cells: 61.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 11.7" "Prostate - Fibroblasts, Skin - Endothelial cells" "Region enriched" "Detected in some" 6 "cerebellum: 8.7" "Group enriched" "Detected in all" 5 "hippocampal formation: 20.1;spinal cord: 9.6" HPA043605 Uncertain Approved Nucleoplasm,Nucleoli "Secreted in other tissues" "Growth factor" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "HPA043605: AB_10960215" "unprognostic (4.65e-1)" "unprognostic (7.62e-2)" "unprognostic (2.50e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (3.62e-2)" "unprognostic (5.74e-3)" "unprognostic (2.56e-2)" "unprognostic (7.30e-2)" "unprognostic (5.79e-2)" "unprognostic (1.91e-3)" "unprognostic (1.22e-3)" "unprognostic (7.59e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-3)" FGF8 AIGF ENSG00000107831 "Fibroblast growth factor 8" P55075 10 101770109-101780371 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "skeletal muscle: 34.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.1;testis cancer: 3.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 4 "Sarcoma: 14.3" "Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Growth factor" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 38: Proximal tubular cells - Transmembrane transport" "unprognostic (1.56e-1)" "unprognostic (3.90e-3)" "unprognostic (1.12e-2)" "unprognostic (4.88e-1)" "unprognostic (2.47e-2)" "unprognostic (9.09e-2)" "unprognostic (8.75e-3)" "unprognostic (8.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.95e-2)" "unprognostic (1.17e-2)" "unprognostic (2.35e-9)" "unprognostic (6.17e-3)" "unprognostic (9.01e-2)" "unprognostic (1.97e-1)" FGF9 ENSG00000102678 "Fibroblast growth factor 9" P31371 13 21671073-21704498 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.0;kidney: 10.4;retina: 8.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 30.5;Excitatory neurons: 35.5;Horizontal cells: 51.6;Inhibitory neurons: 52.5;Muller glia cells: 115.7" "Group enriched" "Detected in some" 5 "endometrial cancer: 3.7;ovarian cancer: 1.2;renal cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.0" "Adipose visceral - Mesothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067007 Enhanced Approved "Secreted in other tissues" "Growth factor" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 10: Muller glia cells - Visual perception" "HPA067007: AB_2732755" "unprognostic (6.59e-3)" "unprognostic (9.09e-3)" "unprognostic (2.15e-2)" "unprognostic (9.24e-2)" "unprognostic (2.19e-1)" "unprognostic (2.37e-2)" "unprognostic (7.42e-4)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (3.86e-1)" "unprognostic (2.38e-3)" "unprognostic (7.93e-2)" "prognostic favorable (1.70e-6)" "unprognostic (5.38e-2)" "unprognostic (1.27e-1)" "unprognostic (3.49e-1)" "unprognostic (6.92e-2)" FGFBP1 "FGFBP, HBP17" ENSG00000137440 "Fibroblast growth factor binding protein 1" Q14512 4 15935577-15938740 "Cancer-related genes, Predicted secreted proteins" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 113.9;esophagus: 409.9;vagina: 167.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 906.0;Basal respiratory cells: 573.1;Ionocytes: 251.4;Squamous epithelial cells: 587.5;Suprabasal keratinocytes: 1258.7" "Group enriched" "Detected in many" 5 "cervical cancer: 117.5;head and neck cancer: 246.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 379.0;head and neck cancer: 386.0" "Colon - Colon enterocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA004332 Enhanced "Secreted in other tissues" Other NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "HPA004332: AB_1078856" "unprognostic (2.87e-3)" "unprognostic (3.55e-1)" "unprognostic (5.03e-2)" "unprognostic (6.99e-2)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (5.03e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-2)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (3.31e-3)" FGFBP2 KSP37 ENSG00000137441 "Fibroblast growth factor binding protein 2" Q9BYJ0 4 15960245-15969309 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 28.1;bone marrow: 53.7" "Cell type enriched" "Detected in many" 10 "NK-cells: 1186.6" "Group enriched" "Detected in many" 9 "glioma: 4.8;head and neck cancer: 13.1;lung cancer: 16.7;melanoma: 16.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 552.5;memory CD8 T-cell: 331.9" "Lineage enriched" "Detected in many" 8 "T-cells: 552.5" "Group enriched" "Detected in some" 16 "Rhabdoid: 72.7;skin cancer: 19.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung)" "Secreted to blood" Other NA NA 346000000 36000000 "Cluster 24: Non-specific - Transcription" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 5: Rhabdoid - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" 1 "unprognostic (3.51e-3)" "unprognostic (8.81e-3)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-2)" "unprognostic (1.54e-1)" "unprognostic (6.14e-2)" "unprognostic (1.35e-2)" "unprognostic (9.89e-2)" "unprognostic (1.76e-1)" "unprognostic (2.55e-2)" "unprognostic (3.33e-1)" "unprognostic (3.51e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (9.61e-2)" "unprognostic (1.49e-2)" FGFBP3 "C10orf13, MGC39320" ENSG00000174721 "Fibroblast growth factor binding protein 3" Q8TAT2 10 91906584-91909486 "Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 20.0;Muller glia cells: 27.2" "Cancer enhanced" "Detected in many" "glioma: 4.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.7" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 15 "Rhabdoid: 67.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA053943 Uncertain "Secreted in brain" Other NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" "HPA053943: AB_2682318" "unprognostic (8.66e-2)" "unprognostic (6.00e-2)" "unprognostic (4.47e-2)" "unprognostic (2.88e-1)" "unprognostic (9.98e-3)" "unprognostic (7.76e-2)" "unprognostic (1.43e-1)" "unprognostic (1.96e-2)" "unprognostic (1.06e-1)" "unprognostic (1.12e-1)" "unprognostic (3.39e-3)" "unprognostic (2.61e-1)" "unprognostic (3.90e-1)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "unprognostic (2.63e-1)" "unprognostic (6.76e-3)" FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability, Lacrimo-auriculo-dento-digital syndrome, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 594.1" "Group enriched" "Detected in many" 5 "Astrocytes: 216.4;Cholangiocytes: 190.8;Oligodendrocytes: 523.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 3.0;eosinophil: 2.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Gastric cancer: 171.5" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" Receptor NA NA 1200000 "Cluster 46: Basophils - Proteolysis" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 7 "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" FGFR3 "ACH, CD333, CEK2, JTK4" ENSG00000068078 "Fibroblast growth factor receptor 3" P22607 4 1793293-1808872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 155.8;esophagus: 135.7;skin 1: 264.2" "Cell type enhanced" "Detected in many" "Astrocytes: 389.2;Basal keratinocytes: 98.3;Cholangiocytes: 70.6;Suprabasal keratinocytes: 96.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 150.3" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004231, HPA067204" Enhanced Supported "Endoplasmic reticulum" "Secreted - unknown location" Receptor NA NA 2500000 "Cluster 80: Non-specific - Endocytosis" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 47: Astrocytes - Unknown function" 192 "Endoplasmic reticulum" "CAB004231: AB_627596, HPA067204: AB_2685804" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (5.90e-2)" "unprognostic (1.24e-3)" "unprognostic (7.22e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.88e-2)" "unprognostic (1.30e-1)" "unprognostic (9.11e-3)" "unprognostic (1.98e-1)" "unprognostic (4.74e-2)" "unprognostic (1.97e-1)" FGFR4 "CD334, JTK2" ENSG00000160867 "Fibroblast growth factor receptor 4" P22455 5 177086905-177098144 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 80.5;lung: 63.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 61.1;Enteroendocrine cells: 17.0;Hepatocytes: 23.4;Proximal tubular cells: 17.0;Undifferentiated cells: 32.0" "Cancer enhanced" "Detected in many" "liver cancer: 42.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "liver cancer: 117.0" "Liver - Hepatocytes, Lung - Fibroblast_1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005196, HPA027273, HPA027369, HPA028251" Approved "Intracellular and membrane" Receptor NA NA 7400000 "Cluster 47: Spleen - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 2: Skeletal myocytes - Muscle contraction" 3 "CAB005196: AB_631512, HPA027273: AB_10600212, HPA027369: AB_10599427, HPA028251: AB_10601221" "unprognostic (1.96e-1)" "unprognostic (2.10e-2)" "unprognostic (1.12e-1)" "unprognostic (9.06e-3)" "unprognostic (2.87e-1)" "unprognostic (1.95e-2)" "unprognostic (7.85e-3)" "unprognostic (9.19e-2)" "unprognostic (4.25e-1)" "unprognostic (4.46e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.71e-3)" "unprognostic (2.41e-1)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" FGG ENSG00000171557 "Fibrinogen gamma chain" P02679 4 154604134-154612967 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 330 "liver: 16058.1" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 9849.5" "Cancer enriched" "Detected in many" 19 "liver cancer: 1503.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "liver cancer: 229.6" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027529, CAB033120, HPA074638" Supported Approved "Endoplasmic reticulum" "Secreted to blood" "Blood coagulation" NA NA 267000000000 73000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Hepatocytes - Metabolism" 3 "Endoplasmic reticulum" "CAB033120: AB_2103818, HPA027529: AB_10601322, HPA074638: " "unprognostic (1.26e-2)" "unprognostic (4.77e-3)" "unprognostic (6.33e-3)" "unprognostic (3.69e-3)" "unprognostic (2.18e-3)" "unprognostic (9.63e-2)" "unprognostic (7.57e-3)" "prognostic unfavorable (1.00e-6)" "unprognostic (1.75e-3)" "unprognostic (3.21e-1)" "unprognostic (1.14e-1)" FGL1 "HFREP-1, HPS" ENSG00000104760 "Fibrinogen like 1" Q08830 8 17864380-17910365 "Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 4058.4" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 7048.4" "Cancer enriched" "Detected in some" 40 "liver cancer: 399.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Gastric cancer: 14.9;liver cancer: 57.2" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" Immunity NA NA 57000000 "Cluster 83: Liver - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 1 "unprognostic (3.62e-2)" "unprognostic (1.14e-2)" "unprognostic (1.75e-5)" "unprognostic (3.00e-1)" "unprognostic (3.54e-2)" "unprognostic (7.89e-2)" "unprognostic (2.15e-1)" "unprognostic (2.62e-1)" "unprognostic (2.71e-1)" "unprognostic (1.09e-2)" "unprognostic (2.86e-7)" "prognostic unfavorable (5.38e-4)" "unprognostic (3.62e-1)" "unprognostic (2.58e-2)" "unprognostic (1.35e-1)" FGL2 "pT49, T49" ENSG00000127951 "Fibrinogen like 2" Q14314 7 77193369-77199848 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 158.3" "Cell type enhanced" "Detected in many" "Kupffer cells: 481.1;Langerhans cells: 675.1;Macrophages: 473.9;monocytes: 1350.3;Schwann cells: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 45 "classical monocyte: 256.3;eosinophil: 226.5;intermediate monocyte: 380.2;myeloid DC: 159.9;neutrophil: 295.2;non-classical monocyte: 381.5" "Group enriched" "Detected in all" 59 "dendritic cells: 159.9;granulocytes: 295.2;monocytes: 381.5" "Group enriched" "Detected in some" 5 "breast cancer: 9.9;Leukemia: 3.5;skin cancer: 13.7" "Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021011, HPA026682" Enhanced "Secreted to blood" "No annotated function" NA NA 38800000 7800000 "Cluster 7: Non-specific - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 29: Monocytes - Innate immune response" 1 "HPA021011: AB_1848532, HPA026682: AB_1848533" "unprognostic (9.80e-3)" "unprognostic (4.70e-3)" "unprognostic (1.19e-1)" "unprognostic (3.51e-3)" "unprognostic (1.62e-1)" "unprognostic (1.00e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-2)" "unprognostic (3.49e-1)" "unprognostic (2.70e-1)" "unprognostic (3.19e-1)" "unprognostic (1.27e-1)" "unprognostic (1.19e-1)" "unprognostic (5.00e-2)" "unprognostic (1.91e-2)" "unprognostic (2.33e-1)" "unprognostic (7.01e-2)" FHOD3 "FHOS2, FLJ22297, FLJ22717, KIAA1695" ENSG00000134775 "Formin homology 2 domain containing 3" Q2V2M9 18 36297713-36780220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 167.2" "Cell type enhanced" "Detected in many" "Astrocytes: 99.1;Cone photoreceptor cells: 73.1;Excitatory neurons: 127.6;Inhibitory neurons: 179.2;Oligodendrocyte precursor cells: 107.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021827, HPA024696" Uncertain "Intracellular and membrane" Other NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA021827: AB_1848571, HPA024696: AB_1848573" "unprognostic (8.46e-2)" "unprognostic (8.76e-2)" "unprognostic (6.34e-2)" "unprognostic (3.44e-1)" "unprognostic (8.96e-2)" "unprognostic (8.30e-2)" "unprognostic (4.11e-4)" "unprognostic (2.73e-2)" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (2.16e-3)" "unprognostic (4.55e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.64e-2)" "unprognostic (4.10e-2)" "unprognostic (3.00e-3)" "unprognostic (1.20e-1)" FIBIN MGC24932 ENSG00000176971 "Fin bud initiation factor homolog" Q8TAL6 11 26994112-26997087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 31.0;Fibroblasts: 82.0;Leydig cells: 41.2;Oligodendrocyte precursor cells: 30.2;Ovarian stromal cells: 30.2;Peritubular cells: 40.2;Schwann cells: 45.2" "Cancer enhanced" "Detected in all" "glioma: 48.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "Rhabdoid: 103.1" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040120 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" "HPA040120: AB_10795243" "unprognostic (1.72e-1)" "unprognostic (2.61e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (1.62e-2)" "unprognostic (5.42e-2)" "unprognostic (7.28e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (5.08e-3)" "unprognostic (3.16e-2)" "unprognostic (2.20e-1)" "prognostic favorable (1.93e-5)" "prognostic unfavorable (6.72e-4)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.85e-6)" "unprognostic (1.02e-2)" FICD "HIP13, HYPE" ENSG00000198855 "FIC domain protein adenylyltransferase" Q9BVA6 12 108515277-108525837 "Enzymes, Predicted intracellular proteins" "Unfolded protein response" "Hydrolase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 46.3;Late spermatids: 67.5;Syncytiotrophoblasts: 35.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021390, HPA071134" Approved Approved Nucleoplasm "Intracellular and membrane" Enzyme NA NA "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 1 Nucleoplasm "HPA021390: AB_1851340, HPA071134: AB_2686347" "unprognostic (1.00e-1)" "unprognostic (8.76e-2)" "unprognostic (1.76e-2)" "prognostic favorable (4.61e-5)" "unprognostic (6.92e-2)" "unprognostic (2.68e-2)" "unprognostic (5.73e-2)" "unprognostic (2.84e-2)" "unprognostic (8.68e-2)" "unprognostic (2.57e-1)" "unprognostic (3.15e-2)" "unprognostic (1.19e-1)" "unprognostic (7.66e-2)" "unprognostic (1.56e-2)" "unprognostic (6.22e-2)" "unprognostic (3.12e-2)" "unprognostic (3.65e-2)" FJX1 "FLJ22416, FLJ25593" ENSG00000179431 "Four-jointed box kinase 1" Q86VR8 11 35618460-35620865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.1;Cytotrophoblasts: 25.7;Endometrial stromal cells: 34.1" "Cancer enhanced" "Detected in all" "glioma: 34.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059220 Uncertain Approved Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 9: Endometrial stromal cells - Transcription" Vesicles "HPA059220: AB_2683950" "unprognostic (8.99e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-3)" "unprognostic (5.20e-2)" "unprognostic (5.72e-2)" "unprognostic (9.56e-3)" "unprognostic (5.16e-2)" "unprognostic (1.06e-2)" "unprognostic (1.74e-1)" "unprognostic (4.39e-3)" "unprognostic (5.28e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (9.24e-9)" "unprognostic (1.64e-2)" "unprognostic (9.64e-2)" "unprognostic (8.35e-2)" "prognostic unfavorable (6.56e-4)" FKBP10 "FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65" ENSG00000141756 "FKBP prolyl isomerase 10" Q96AY3 17 41812680-41823213 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 75.9;Fibroblasts: 95.3;Leydig cells: 46.2;Mesothelial cells: 56.4;Peritubular cells: 43.8;Smooth muscle cells: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013808, HPA051171, HPA057021" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 110000 "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 2 "Golgi apparatus" "HPA013808: , HPA051171: AB_2681371, HPA057021: AB_2683312" "unprognostic (8.30e-2)" "prognostic unfavorable (4.16e-4)" "unprognostic (9.05e-2)" "unprognostic (1.71e-2)" "unprognostic (4.77e-2)" "unprognostic (2.95e-2)" "unprognostic (1.14e-2)" "unprognostic (9.98e-2)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.34e-2)" "unprognostic (5.77e-2)" "prognostic unfavorable (3.43e-5)" "prognostic unfavorable (4.99e-4)" FKBP14 "FKBP22, FLJ20731" ENSG00000106080 "FKBP prolyl isomerase 14" Q9NWM8 7 30010587-30026702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isomerase, Rotamase" "Deafness, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Colon - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013329, HPA026829" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 67: Non-specific - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" Cytosol "Nucleoplasm, Golgi apparatus" "HPA013329: AB_1848613, HPA026829: AB_10601651" "prognostic unfavorable (1.60e-4)" "unprognostic (1.12e-3)" "unprognostic (6.84e-2)" "unprognostic (1.23e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (6.06e-2)" "unprognostic (7.00e-2)" "unprognostic (6.99e-2)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.93e-3)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "prognostic unfavorable (4.25e-4)" FKBP2 "FKBP-13, FKBP13, PPIase" ENSG00000173486 "FKBP prolyl isomerase 2" P26885 11 64241003-64244132 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 448.9;Proximal tubular cells: 190.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 931.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" Enzyme No No 510000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 5 "Plasma membrane" "CAB025561: , HPA049405: AB_2680749" "unprognostic (4.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.77e-2)" "unprognostic (2.66e-3)" "unprognostic (7.40e-2)" "unprognostic (1.92e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-1)" "unprognostic (3.23e-1)" "unprognostic (5.91e-3)" "unprognostic (5.86e-2)" "unprognostic (7.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (5.23e-1)" "unprognostic (2.30e-1)" "unprognostic (3.57e-2)" FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 54.4" "Cell type enhanced" "Detected in many" "Early spermatids: 146.3;Endometrial stromal cells: 56.0;Fibroblasts: 58.1;Leydig cells: 64.8;Ovarian stromal cells: 91.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 62: Connective tissue - ECM organization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 59 "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 85.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" Enzyme No No 63000 "Cluster 35: Neutrophils - Protein binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" FKRP "FKTR, LGMD2I, MDC1C" ENSG00000181027 "Fukutin related protein" Q9H9S5 19 46746046-46776988 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transferase "Cardiomyopathy, Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043115, HPA060454" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" Enzyme NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 62: Hepatocytes - Metabolism" 1 "Nucleoplasm, Golgi apparatus, Cytosol" "HPA043115: AB_2678324, HPA060454: AB_2684281" "unprognostic (4.44e-2)" "unprognostic (5.20e-2)" "unprognostic (2.19e-2)" "unprognostic (8.37e-3)" "unprognostic (1.83e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (3.85e-1)" "unprognostic (2.99e-2)" "unprognostic (4.59e-3)" "prognostic favorable (8.98e-4)" "unprognostic (3.53e-1)" "unprognostic (2.30e-2)" "unprognostic (2.53e-1)" "unprognostic (2.46e-1)" "unprognostic (1.01e-1)" "unprognostic (2.53e-2)" FLRT2 ENSG00000185070 "Fibronectin leucine rich transmembrane protein 2" O43155 14 85530144-85654428 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 39.7" "Cell type enhanced" "Detected in many" "Astrocytes: 265.0;Excitatory neurons: 531.8;Inhibitory neurons: 307.0;Leydig cells: 210.3;Microglial cells: 413.3;Oligodendrocyte precursor cells: 199.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 27.1" "Colon - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "Developmental protein" NA NA 17000 "Cluster 68: Non-specific - Protein processing" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (8.13e-3)" "unprognostic (4.59e-3)" "unprognostic (3.57e-2)" "unprognostic (1.46e-2)" "unprognostic (4.75e-2)" "unprognostic (9.46e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (5.34e-2)" "unprognostic (8.02e-6)" "unprognostic (1.98e-3)" "unprognostic (8.03e-2)" "unprognostic (1.50e-2)" "unprognostic (1.50e-5)" FLRT3 ENSG00000125848 "Fibronectin leucine rich transmembrane protein 3" Q9NZU0 20 14322985-14337614 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 22.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 229.3;Alveolar cells type 2: 160.4;Basal prostatic cells: 69.4;Mesothelial cells: 71.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056033 Enhanced Supported "Plasma membrane,Cell Junctions,Cytosol" "Intracellular and membrane" "Developmental protein" NA NA 1100000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" 1 "Plasma membrane" "Cell Junctions, Cytosol" "HPA056033: AB_2683016" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (2.98e-1)" "unprognostic (1.14e-3)" "unprognostic (2.30e-1)" "unprognostic (6.00e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.85e-5)" "unprognostic (1.24e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.05e-1)" "prognostic favorable (1.49e-7)" "unprognostic (1.54e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-3)" "unprognostic (3.65e-1)" FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "placenta: 405.3" "Cell type enhanced" "Detected in many" "Adipocytes: 383.1;Endothelial cells: 364.4;Extravillous trophoblasts: 980.8;Microglial cells: 414.2;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 15.1;testis cancer: 39.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" Receptor NA NA 876000 87000 "Cluster 58: Placenta - Pregnancy" "Cluster 47: Endothelial cells - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" 6 "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" FLT3LG ENSG00000090554 "Fms related receptor tyrosine kinase 3 ligand" P49771 19 49474207-49486231 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 19.2;T-cells: 50.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 77.9;MAIT T-cell: 144.7;memory CD4 T-cell: 158.7;memory CD8 T-cell: 102.0;naive CD4 T-cell: 170.1;naive CD8 T-cell: 138.2;T-reg: 171.5" "Lineage enriched" "Detected in all" 6 "T-cells: 171.5" "Low cancer specificity" "Detected in many" "Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" Cytokine NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 1 "unprognostic (1.29e-3)" "prognostic favorable (2.17e-5)" "unprognostic (2.12e-3)" "unprognostic (9.16e-2)" "unprognostic (3.05e-1)" "unprognostic (3.81e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (1.03e-2)" "unprognostic (6.07e-2)" "unprognostic (1.16e-2)" "unprognostic (2.88e-1)" "unprognostic (7.78e-6)" "unprognostic (2.17e-1)" "unprognostic (5.25e-2)" "unprognostic (8.22e-3)" "unprognostic (5.68e-2)" FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Lymphatic endothelial cells: 193.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 14 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" Receptor NA NA 20000000 290000000 "Cluster 1: T-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 54: Non-specific - Transcription" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 2 "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" FMOD SLRR2E ENSG00000122176 Fibromodulin Q06828 1 203340628-203351758 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 52.8;Intestinal goblet cells: 75.3;Mesothelial cells: 47.4;Ovarian stromal cells: 46.1;Prostatic glandular cells: 34.3;Smooth muscle cells: 37.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 17.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "breast cancer: 43.2;skin cancer: 19.0;thyroid cancer: 17.1" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 94.0" "Secreted to extracellular matrix" "No annotated function" NA NA 2600000 "Cluster 62: Connective tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" "unprognostic (1.48e-1)" "unprognostic (8.88e-2)" "unprognostic (9.35e-2)" "unprognostic (2.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.17e-3)" "unprognostic (1.86e-1)" "unprognostic (3.30e-1)" "unprognostic (5.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (9.40e-3)" "unprognostic (3.58e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (2.67e-4)" FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1674.5;placenta: 2828.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 3161.0;Fibroblasts: 697.7;Hepatocytes: 800.2;Pancreatic endocrine cells: 517.9;Smooth muscle cells: 482.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 4284.8;thyroid cancer: 4456.7" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" "Acute phase" NA NA 227000000000 47000000000 "Cluster 11: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 21 "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" FNDC1 "bA243O10.1, dJ322A24.1, FNDC2, KIAA1866" ENSG00000164694 "Fibronectin type III domain containing 1" Q4ZHG4 6 159169400-159272108 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 13.7;intestine: 12.4;thyroid gland: 19.7" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 4.2;Fibroblasts: 20.1;Skeletal myocytes: 5.9;Smooth muscle cells: 8.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 32.5" "Group enriched" "Detected in many" 6 "cerebral cortex: 11.9;hippocampal formation: 18.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 12.8;Kidney cancer: 9.5;Rhabdoid: 18.7" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skin - Fibroblast_1, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Region enhanced" "Detected in many" "spinal cord: 12.5" "HPA030962, HPA030963" Approved Approved "Nuclear speckles" "Secreted to extracellular matrix" "No annotated function" NA NA 14000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "Nuclear speckles" "HPA030962: AB_10696212, HPA030963: AB_2673676" "unprognostic (4.59e-2)" "unprognostic (9.17e-3)" "unprognostic (7.62e-2)" "prognostic favorable (6.10e-5)" "unprognostic (4.57e-1)" "unprognostic (2.11e-1)" "unprognostic (5.52e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "unprognostic (4.18e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.93e-6)" "unprognostic (6.49e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.76e-3)" FNDC4 "FLJ22362, FRCP1" ENSG00000115226 "Fibronectin type III domain containing 4" Q9H6D8 2 27491883-27495200 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 120.3;liver: 123.8" "Cell type enhanced" "Detected in many" "Early spermatids: 183.9;Hepatocytes: 133.4;Late spermatids: 613.6" "Cancer enhanced" "Detected in all" "glioma: 39.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 16.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051804, HPA063581" Uncertain Approved Nucleoplasm,Aggresome,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 36: Late spermatids - Unknown function" Nucleoplasm "Aggresome, Cytosol" "HPA051804: AB_2681617, HPA063581: AB_2685048" "unprognostic (2.57e-1)" "unprognostic (1.19e-3)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.46e-3)" "unprognostic (1.27e-1)" "unprognostic (4.77e-3)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (9.64e-2)" "unprognostic (8.28e-3)" "unprognostic (4.41e-2)" "unprognostic (1.28e-2)" "unprognostic (1.13e-2)" "unprognostic (5.74e-3)" "unprognostic (2.40e-3)" "prognostic unfavorable (6.11e-4)" FNDC5 FRCP2 ENSG00000160097 "Fibronectin type III domain containing 5" Q8NAU1 1 32862268-32872482 "Predicted membrane proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 311.6;tongue: 459.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 52.9;Cardiomyocytes: 83.0;Horizontal cells: 44.1;Muller glia cells: 39.7;Serous glandular cells: 38.6;Skeletal myocytes: 45.9" "Group enriched" "Detected in many" 7 "glioma: 4.2;liver cancer: 10.0;testis cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Neuroblastoma: 21.7;Sarcoma: 36.8" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051290 Enhanced "Intracellular and membrane" Hormone NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 53: Fibroblasts - ECM organization" "HPA051290: AB_2681422" "unprognostic (4.36e-2)" "unprognostic (9.08e-3)" "unprognostic (7.62e-4)" "unprognostic (1.03e-2)" "unprognostic (3.77e-2)" "unprognostic (6.26e-2)" "unprognostic (5.68e-2)" "unprognostic (2.76e-2)" "unprognostic (1.45e-2)" "unprognostic (1.83e-1)" "unprognostic (3.15e-3)" "unprognostic (1.63e-1)" "unprognostic (9.07e-2)" "unprognostic (7.07e-3)" "unprognostic (1.13e-1)" "unprognostic (3.37e-3)" "unprognostic (1.33e-2)" FNDC7 FLJ35838 ENSG00000143107 "Fibronectin type III domain containing 7" Q5VTL7 1 108712908-108742749 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Early spermatids: 5.1;Horizontal cells: 1.3;Late spermatids: 1.8;Oligodendrocyte precursor cells: 3.3;Oligodendrocytes: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028079, HPA054297" Enhanced Approved "Nucleoplasm,Actin filaments" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 18: Early spermatids - Unknown function" "Actin filaments" Nucleoplasm "HPA028079: AB_10602501, HPA054297: AB_2682441" "unprognostic (2.35e-2)" "unprognostic (2.65e-2)" "unprognostic (3.74e-1)" "unprognostic (8.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-4)" "unprognostic (1.90e-10)" "unprognostic (1.59e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" FOLR1 "FOLR, FRalpha" ENSG00000110195 "Folate receptor alpha" P15328 11 72189558-72196323 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Transport Receptor "FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "choroid plexus: 2944.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 387.7;Alveolar cells type 2: 264.2;Breast glandular cells: 223.4;Ciliated cells: 209.6;Collecting duct cells: 254.8;Cytotrophoblasts: 468.5;Proximal tubular cells: 245.3;Secretory cells: 415.8;Syncytiotrophoblasts: 323.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 259.5" "Region enriched" "Detected in all" 38 "choroid plexus: 993.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 85.2" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 1, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" Receptor NA NA 448000 140000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 17: Breast glandular cells - Lactation" 1 "unprognostic (3.30e-1)" "unprognostic (2.19e-1)" "unprognostic (6.55e-2)" "unprognostic (3.49e-2)" "unprognostic (7.67e-3)" "unprognostic (1.98e-2)" "prognostic unfavorable (2.50e-4)" "unprognostic (1.18e-2)" "unprognostic (8.13e-2)" "unprognostic (2.47e-2)" "unprognostic (2.58e-2)" "unprognostic (2.87e-3)" "unprognostic (1.67e-1)" "unprognostic (2.52e-1)" "unprognostic (1.11e-1)" "unprognostic (2.20e-1)" "unprognostic (2.69e-1)" FOLR2 FRbeta ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 162.7" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.4;intermediate monocyte: 50.8" "Group enriched" "Detected in many" 4 "dendritic cells: 18.8;monocytes: 64.4" "Group enriched" "Detected in some" 18 "Leukemia: 1.8;lymphoma: 4.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Receptor NA NA 15000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 58: Placenta - Pregnancy" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" FOLR3 "FR-G, FRgamma" ENSG00000110203 "Folate receptor gamma" P41439 11 72114869-72139892 "Metabolic proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 94.5" "Cell type enriched" "Detected in some" 16 "Distal tubular cells: 387.3" "Cancer enhanced" "Detected in some" "ovarian cancer: 5.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "classical monocyte: 325.3;neutrophil: 490.4" "Group enriched" "Detected in many" 11 "granulocytes: 490.4;monocytes: 325.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.2;Sarcoma: 5.6" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils" "Secreted to blood" Receptor NA NA 12000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Neutrophils - Degranulation" 1 "unprognostic (1.47e-2)" "unprognostic (6.26e-3)" "unprognostic (1.94e-2)" "unprognostic (8.72e-3)" "unprognostic (6.87e-3)" "unprognostic (9.56e-2)" "unprognostic (1.58e-1)" "unprognostic (3.72e-1)" "unprognostic (1.72e-1)" "unprognostic (1.54e-1)" "unprognostic (7.35e-2)" "unprognostic (7.90e-2)" "unprognostic (8.39e-2)" "unprognostic (9.99e-4)" "unprognostic (1.96e-1)" "unprognostic (2.03e-6)" "unprognostic (4.17e-1)" FOXRED2 "ERFAD, FLJ23322" ENSG00000100350 "FAD dependent oxidoreductase domain containing 2" Q8IWF2 22 36487190-36507221 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 21.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 5.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 5.3" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031611, HPA031612" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 66: Non-specific - Mitochondria" "Cluster 58: Macrophages - Innate immune response" 1 "HPA031611: AB_10599975, HPA031612: AB_10601887" "unprognostic (3.66e-1)" "prognostic favorable (4.86e-5)" "unprognostic (6.73e-2)" "unprognostic (1.26e-1)" "unprognostic (4.66e-1)" "unprognostic (7.58e-2)" "unprognostic (2.24e-3)" "unprognostic (2.00e-2)" "unprognostic (4.31e-1)" "unprognostic (7.15e-3)" "unprognostic (1.67e-2)" "unprognostic (1.48e-2)" "unprognostic (2.15e-2)" "unprognostic (9.56e-3)" "unprognostic (4.49e-1)" "prognostic unfavorable (9.32e-4)" "unprognostic (9.42e-2)" FPGS ENSG00000136877 "Folylpolyglutamate synthase" Q05932 9 127794597-127814327 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Ligase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mesothelial cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050488 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 45: Non-specific - Mixed function" "HPA050488: AB_2681143" "unprognostic (6.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.02e-1)" "prognostic favorable (9.08e-4)" "unprognostic (1.25e-1)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (6.25e-2)" "unprognostic (2.63e-1)" "unprognostic (1.16e-1)" "unprognostic (6.97e-2)" "unprognostic (1.76e-1)" "unprognostic (8.54e-3)" "unprognostic (2.61e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" FRAS1 "FLJ14927, FLJ22031, KIAA1500" ENSG00000138759 "Fraser extracellular matrix complex subunit 1" Q86XX4 4 78057323-78544269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 11.6" "Group enriched" "Detected in many" 10 "Excitatory neurons: 197.6;Inhibitory neurons: 362.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051601 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 8: Neurons - Neuronal signaling" "HPA051601: AB_2681547" "unprognostic (1.33e-2)" "unprognostic (1.04e-2)" "unprognostic (9.37e-2)" "unprognostic (8.91e-2)" "unprognostic (2.97e-1)" "unprognostic (2.04e-1)" "unprognostic (1.45e-3)" "unprognostic (2.02e-2)" "unprognostic (1.07e-1)" "unprognostic (2.69e-2)" "unprognostic (2.09e-2)" "unprognostic (4.02e-2)" "prognostic favorable (4.69e-4)" "unprognostic (2.56e-1)" "unprognostic (1.10e-1)" "unprognostic (4.78e-3)" "unprognostic (6.09e-2)" FREM1 "C9orf143, C9orf145, C9orf154, DKFZp686M16108, FLJ25461, TILRR" ENSG00000164946 "FRAS1 related extracellular matrix 1" Q5H8C1 9 14737152-14910995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 35.6" "Group enriched" "Detected in many" 6 "Early spermatids: 49.2;Inhibitory neurons: 120.1;Late spermatids: 146.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 4.9;Rhabdoid: 5.9" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" "Developmental protein" NA NA 58000 "Cluster 53: Non-specific - Glycosylation" "Cluster 25: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 65: Neurons - Synaptic function" "unprognostic (1.13e-5)" "unprognostic (2.59e-3)" "unprognostic (2.89e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (6.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.66e-3)" "unprognostic (4.43e-1)" "unprognostic (1.31e-1)" "unprognostic (3.62e-2)" "unprognostic (6.23e-2)" "unprognostic (8.95e-13)" "unprognostic (2.28e-3)" "unprognostic (8.53e-2)" "unprognostic (3.41e-2)" "unprognostic (2.86e-1)" FREM3 ENSG00000183090 "FRAS1 related extracellular matrix 3" P0C091 4 143577302-143700675 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.2" "Cell type enhanced" "Detected in some" "Astrocytes: 1.5;Excitatory neurons: 9.4;Inhibitory neurons: 3.4;Oligodendrocyte precursor cells: 4.2;Oligodendrocytes: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 3.1;hypothalamus: 2.8;thalamus: 4.4" HPA041641 Uncertain "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "HPA041641: AB_2677592" "unprognostic (1.19e-2)" "unprognostic (4.09e-9)" "unprognostic (3.09e-3)" "unprognostic (2.74e-1)" "unprognostic (1.66e-1)" "unprognostic (4.74e-2)" "unprognostic (1.98e-1)" "unprognostic (1.91e-1)" "unprognostic (2.68e-1)" "unprognostic (2.17e-1)" "unprognostic (1.46e-1)" "unprognostic (2.30e-1)" "unprognostic (7.11e-3)" "unprognostic (3.24e-1)" FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 152.8;lymphoid tissue: 86.6;retina: 326.6;tongue: 111.8" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 3313.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 98.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 23.1;Neuroblastoma: 12.5" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Eccrine sweat gland cells" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" "Developmental protein" NA NA 44000 "Cluster 39: Retina & Testis - Cilium" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 10: Muller glia cells - Visual perception" 1 "unprognostic (5.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.64e-2)" "unprognostic (2.38e-2)" "unprognostic (4.67e-2)" "unprognostic (8.58e-2)" "unprognostic (5.41e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (3.53e-2)" "unprognostic (1.05e-2)" "unprognostic (6.04e-2)" "unprognostic (3.21e-1)" FSHB ENSG00000131808 "Follicle stimulating hormone subunit beta" P01225 11 30231014-30235261 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 292 "pituitary gland: 232.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB023410, HPA069703" Enhanced "Secreted to blood" Hormone NA NA 78000 "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 51: Neurons - Mixed function" "Cluster 18: Early spermatids - Unknown function" 1 "CAB023410: AB_324983, HPA069703: AB_2686176" "unprognostic (1.04e-1)" FSHR "FSHRO, LGR1, ODG1" ENSG00000170820 "Follicle stimulating hormone receptor" P23945 2 48962157-49154527 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "ovary: 2.7;testis: 2.2" "Cell type enhanced" "Detected in some" "Early spermatids: 1.8;Excitatory neurons: 9.7;Granulosa cells: 5.2;Late spermatids: 8.1;Oligodendrocyte precursor cells: 2.8;Sertoli cells: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Receptor NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 1 "unprognostic (5.94e-2)" "unprognostic (4.06e-3)" "unprognostic (5.78e-2)" FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 67.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 62.8;Fibroblasts: 62.4;Granulosa cells: 60.1;Hepatocytes: 48.6;Salivary duct cells: 43.5;Skeletal myocytes: 210.8" "Cancer enhanced" "Detected in all" "liver cancer: 45.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 415.0;head and neck cancer: 203.7" "Heart muscle - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" "No annotated function" NA NA 1800000 "Cluster 83: Liver - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 7 Vesicles "CAB026025: , HPA016612: " "unprognostic (1.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (7.73e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-3)" "unprognostic (8.02e-2)" "unprognostic (2.32e-2)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.44e-5)" "unprognostic (1.21e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-1)" FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 394.4;Fibroblasts: 536.5;Leydig cells: 324.4;Peritubular cells: 264.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1295.8" "Kidney - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved Vesicles,Cytosol "Secreted to blood" Other NA NA 34000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 8 "Vesicles, Cytosol" "HPA035251: AB_10601906, HPA040815: AB_2732489" "unprognostic (2.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.84e-2)" "unprognostic (4.54e-3)" "unprognostic (4.10e-2)" "unprognostic (1.35e-1)" "unprognostic (9.88e-2)" "unprognostic (3.05e-2)" "unprognostic (1.19e-2)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (4.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.05e-2)" "unprognostic (4.47e-3)" FSTL3 "FLRG, FSRP" ENSG00000070404 "Follistatin like 3" O95633 19 676392-683392 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Osteogenesis, Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Extravillous trophoblasts: 4317.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 221.3" "Pancreas - Ductal cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB024899, HPA045378" Approved Supported Nucleoplasm "Secreted in other tissues" Transcription NA Yes 7000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 4: Extravillous trophoblasts - Unknown function" Nucleoplasm "CAB024899: , HPA045378: AB_2679300" "unprognostic (9.86e-3)" "unprognostic (1.32e-3)" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.19e-3)" "unprognostic (1.51e-3)" "unprognostic (8.64e-3)" "prognostic unfavorable (4.61e-7)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-3)" "unprognostic (7.22e-3)" "unprognostic (3.07e-1)" "unprognostic (3.75e-1)" "unprognostic (5.89e-3)" FSTL4 KIAA1061 ENSG00000053108 "Follistatin like 4" Q6MZW2 5 133196455-133612541 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 377.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 52.3" "Kidney - Intercalated cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045920 Uncertain Approved "Nuclear membrane,Mitochondria" "Secreted to blood" "No annotated function" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" Mitochondria "Nuclear membrane" "HPA045920: AB_10965844" "unprognostic (5.52e-2)" "unprognostic (2.54e-1)" "unprognostic (5.74e-2)" "unprognostic (8.14e-2)" "unprognostic (1.87e-1)" "unprognostic (3.97e-2)" "unprognostic (6.35e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (4.74e-2)" "unprognostic (8.66e-2)" "unprognostic (3.73e-4)" "unprognostic (2.02e-2)" "unprognostic (9.91e-3)" "unprognostic (1.03e-2)" "unprognostic (4.25e-2)" FSTL5 "DKFZp566D234, KIAA1263" ENSG00000168843 "Follistatin like 5" Q8N475 4 161383897-162164004 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 47.6;retina: 91.9" "Group enriched" "Detected in some" 4 "Bipolar cells: 294.6;Cone photoreceptor cells: 372.1;Excitatory neurons: 178.2;Inhibitory neurons: 494.3;Rod photoreceptor cells: 162.6" "Cancer enriched" "Detected in single" 6 "melanoma: 1.7" "Region enhanced" "Detected in all" "cerebellum: 151.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.7;Sarcoma: 23.3" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 76.9" "Secreted in brain" "No annotated function" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 65: Neurons - Synaptic function" "unprognostic (4.90e-2)" "unprognostic (4.46e-1)" "unprognostic (1.52e-2)" "unprognostic (2.03e-1)" "unprognostic (3.66e-2)" "unprognostic (2.99e-2)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (1.10e-1)" "unprognostic (3.39e-2)" "unprognostic (1.61e-1)" "unprognostic (1.08e-10)" "unprognostic (8.45e-4)" "unprognostic (1.53e-1)" "unprognostic (1.52e-1)" "unprognostic (6.60e-3)" FTCDNL1 FONG ENSG00000226124 "Formiminotransferase cyclodeaminase N-terminal like" E5RQL4 2 199760544-199851192 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 37.8;Excitatory neurons: 42.0;Oligodendrocytes: 107.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA065748, HPA078878" Enhanced Vesicles "Secreted in other tissues" "No annotated function" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 51: Oligodendrocytes - Unknown function" Vesicles "HPA065748: , HPA078878: " "unprognostic (1.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.27e-2)" "unprognostic (9.80e-2)" "unprognostic (3.09e-1)" "unprognostic (7.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.86e-2)" "prognostic favorable (3.31e-4)" "unprognostic (3.92e-2)" "unprognostic (4.63e-2)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.21e-2)" FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 182.1;Distal enterocytes: 193.9;Paneth cells: 181.1;Proximal enterocytes: 220.7;Syncytiotrophoblasts: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Pancreas - Macrophages, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" Enzyme NA NA 60000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" 3 Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494812-143511720 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 159.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" Enzyme NA NA 56000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 77: Plasma cells - Protein processing" 12 "HPA031659: AB_10600661, HPA031661: AB_10601681" "unprognostic (1.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (2.70e-9)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (7.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-3)" "unprognostic (9.18e-2)" "unprognostic (2.69e-1)" "unprognostic (7.25e-2)" "unprognostic (5.07e-2)" FURIN "FUR, PACE, PCSK3, SPC1" ENSG00000140564 "Furin, paired basic amino acid cleaving enzyme" P09958 15 90868588-90883564 "Enzymes, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 298.0;salivary gland: 214.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 100.4;Hepatocytes: 113.1;monocytes: 102.8;Serous glandular cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009499, HPA067869" Enhanced Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 130000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 75: Serous glandular cells - Salivary secretion" 4 "Golgi apparatus" Nucleoplasm "CAB009499: AB_2105095, HPA067869: " "unprognostic (2.46e-1)" "unprognostic (2.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.30e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (9.92e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (4.52e-3)" "unprognostic (4.57e-2)" "unprognostic (4.46e-2)" "unprognostic (4.27e-3)" "unprognostic (8.20e-2)" FUT10 ENSG00000172728 "Fucosyltransferase 10" Q6P4F1 8 33370824-33473146 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 132.8;Early spermatids: 247.4;Late spermatids: 296.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053970, HPA058655" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" "Nucleoplasm, Endoplasmic reticulum, Golgi apparatus" "HPA053970: AB_2682327, HPA058655: AB_2683789" "unprognostic (6.02e-2)" "unprognostic (4.61e-2)" "unprognostic (2.85e-3)" "unprognostic (6.24e-2)" "unprognostic (1.01e-1)" "unprognostic (4.80e-2)" "unprognostic (5.40e-3)" "unprognostic (6.07e-2)" "unprognostic (2.84e-1)" "unprognostic (2.23e-1)" "unprognostic (9.10e-3)" "unprognostic (2.76e-4)" "unprognostic (3.06e-3)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-3)" "unprognostic (6.01e-3)" FUT11 MGC33202 ENSG00000196968 "Fucosyltransferase 11" Q495W5 10 73772276-73780251 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 119.1;Late spermatids: 264.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014033 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 1200000 "Cluster 15: NK-cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Late spermatids - Unknown function" 2 "Nuclear membrane" "Golgi apparatus" "HPA014033: AB_1849192" "prognostic unfavorable (6.78e-4)" "prognostic unfavorable (2.39e-6)" "unprognostic (1.47e-2)" "unprognostic (2.42e-3)" "unprognostic (3.27e-1)" "unprognostic (7.64e-2)" "unprognostic (2.29e-2)" "unprognostic (3.50e-3)" "unprognostic (1.51e-1)" "unprognostic (9.30e-2)" "unprognostic (9.77e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.67e-4)" "unprognostic (2.59e-2)" "unprognostic (1.71e-1)" "unprognostic (3.61e-1)" "unprognostic (2.66e-2)" FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830408-5839722 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 77.2;kidney: 35.1;salivary gland: 44.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 49.2;Intestinal goblet cells: 72.0;Ionocytes: 40.1;Paneth cells: 32.8;Proximal enterocytes: 118.6;Proximal tubular cells: 57.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "colorectal cancer: 7.9;Gastric cancer: 4.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA 51000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "Golgi apparatus" "HPA043707: AB_2678628, HPA046966: AB_2679879" "unprognostic (3.65e-2)" "unprognostic (3.00e-3)" "unprognostic (2.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.02e-2)" "unprognostic (6.68e-3)" "unprognostic (4.01e-2)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (4.94e-2)" "prognostic favorable (3.17e-8)" "unprognostic (1.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115823-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1749.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 612.8;Distal enterocytes: 2942.0;Intestinal goblet cells: 871.0;Paneth cells: 1297.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1961.9" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "spinal cord: 5.1" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" 1 Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" "unprognostic (2.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.37e-3)" "unprognostic (3.31e-3)" "unprognostic (6.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.15e-6)" "unprognostic (4.17e-2)" "unprognostic (2.08e-1)" "unprognostic (5.06e-2)" "unprognostic (7.69e-3)" GABBR1 "GPRC3A, hGB1a" ENSG00000204681 "Gamma-aminobutyric acid type B receptor subunit 1" Q9UBS5 6 29555629-29633976 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 228.8" "Cell type enhanced" "Detected in many" "Astrocytes: 142.7;Excitatory neurons: 56.7;Horizontal cells: 56.0;Inhibitory neurons: 65.2;Oligodendrocyte precursor cells: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050483, HPA058459" Uncertain Approved Centrosome "Intracellular and membrane" Receptor NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Astrocytes - Unknown function" 4 Centrosome "HPA050483: AB_2681140, HPA058459: " "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (3.22e-3)" "unprognostic (2.93e-3)" "unprognostic (3.37e-1)" "unprognostic (2.65e-1)" "unprognostic (7.95e-4)" "unprognostic (5.44e-2)" "unprognostic (4.24e-2)" "unprognostic (1.14e-1)" "prognostic favorable (2.54e-5)" "unprognostic (1.23e-3)" "prognostic unfavorable (3.77e-10)" "unprognostic (3.82e-2)" "unprognostic (2.26e-1)" "unprognostic (3.87e-2)" "unprognostic (2.55e-2)" GABRA2 ENSG00000151834 "Gamma-aminobutyric acid type A receptor subunit alpha2" P47869 4 46243548-46475230 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.6" "Group enriched" "Detected in many" 4 "Astrocytes: 403.5;Excitatory neurons: 151.0;Inhibitory neurons: 106.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.6;glioma: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 7.6" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029363, CAB079061" Supported Uncertain "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 1 "Plasma membrane" Nucleoplasm "CAB079061: , HPA029363: " "unprognostic (2.03e-2)" "unprognostic (2.77e-1)" "unprognostic (2.45e-4)" "unprognostic (6.87e-3)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.09e-1)" "unprognostic (6.90e-3)" "unprognostic (8.83e-2)" "unprognostic (2.22e-5)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "pituitary gland: 862.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 31.2;Ductal cells: 29.4;Endometrial stromal cells: 52.1;Exocrine glandular cells: 28.7;Extravillous trophoblasts: 55.9;Glandular and luminal cells: 25.1;Pancreatic endocrine cells: 86.6" "Cancer enhanced" "Detected in many" "testis cancer: 22.2" "Region enriched" "Detected in all" 13 "hypothalamus: 1423.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 257.1" "Colon - Colon enteroendocrine cells, Skin - Sebaceous gland cells" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in many" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" Hormone NA NA 60000 200000 "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" 6 "Golgi apparatus" Vesicles "CAB079779: , HPA049864: AB_2680922" "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" GAL3ST1 CST ENSG00000128242 "Galactose-3-O-sulfotransferase 1" Q99999 22 30554635-30574665 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 63.9;intestine: 23.7;kidney: 17.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 34.3;Muller glia cells: 33.8;Oligodendrocyte precursor cells: 25.0;Oligodendrocytes: 49.9;Proximal enterocytes: 42.9" "Cancer enriched" "Detected in many" 6 "renal cancer: 38.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 16 "Kidney cancer: 235.5" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001220, HPA077138" Approved Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" Vesicles Nucleoplasm "HPA001220: AB_1078933, HPA077138: " "unprognostic (2.69e-2)" "unprognostic (3.12e-4)" "unprognostic (5.93e-2)" "unprognostic (1.08e-2)" "unprognostic (2.32e-1)" "unprognostic (6.50e-3)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "unprognostic (2.89e-1)" "unprognostic (5.18e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" GAL3ST2 GP3ST ENSG00000154252 "Galactose-3-O-sulfotransferase 2" Q9H3Q3 2 241776822-241804287 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "intestine: 9.1" "Cell type enhanced" "Detected in single" "Mesothelial cells: 1.2" "Group enriched" "Detected in many" 6 "colorectal cancer: 6.7;ovarian cancer: 4.9;stomach cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 7.5" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA071809 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 7: T-cells - T-cell receptor" 1 "HPA071809: AB_2686450" "unprognostic (5.22e-3)" "unprognostic (6.52e-2)" "unprognostic (1.85e-2)" "unprognostic (4.04e-3)" "unprognostic (3.04e-4)" "unprognostic (3.45e-2)" "unprognostic (2.48e-2)" "unprognostic (2.87e-1)" "unprognostic (4.13e-2)" "unprognostic (2.25e-3)" "unprognostic (2.58e-1)" "unprognostic (4.99e-2)" "unprognostic (2.87e-11)" "unprognostic (4.32e-2)" "unprognostic (1.55e-1)" "unprognostic (5.99e-3)" "unprognostic (3.49e-1)" GAL3ST3 GAL3ST2 ENSG00000175229 "Galactose-3-O-sulfotransferase 3" Q96A11 11 66040765-66049161 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.0;thyroid gland: 16.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.6;Cardiomyocytes: 3.8;Cone photoreceptor cells: 8.5;Excitatory neurons: 3.5;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 7.1;Rod photoreceptor cells: 21.5" "Group enriched" "Detected in many" 5 "glioma: 4.7;ovarian cancer: 5.5;thyroid cancer: 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.5" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 64: Neuronal - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" "prognostic unfavorable (6.53e-6)" "unprognostic (1.24e-1)" "unprognostic (3.30e-1)" "unprognostic (1.57e-2)" "unprognostic (2.62e-1)" "unprognostic (6.08e-2)" "unprognostic (2.01e-3)" "unprognostic (7.26e-2)" "unprognostic (2.07e-2)" "unprognostic (1.40e-1)" "unprognostic (5.29e-1)" GALC ENSG00000054983 Galactosylceramidase P54803 14 87837820-87993665 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism, Sphingolipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 210.8;Late spermatids: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022196 Approved "Intracellular and membrane" Enzyme NA NA 53000 "Cluster 25: Non-specific - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 30: Granulocytes - Unknown function" "CAB022196: " "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (9.39e-2)" "unprognostic (3.08e-1)" "unprognostic (9.70e-2)" "unprognostic (1.73e-1)" "unprognostic (6.56e-2)" "unprognostic (8.44e-3)" "unprognostic (8.08e-2)" "unprognostic (1.84e-2)" "unprognostic (6.00e-2)" "unprognostic (2.13e-1)" "unprognostic (6.80e-2)" "unprognostic (2.72e-2)" GALNS "GalN6S, GALNAC6S, GAS" ENSG00000141012 "Galactosamine (N-acetyl)-6-sulfatase" P34059 16 88813734-88856970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Dwarfism, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ciliated cells: 39.0;Spermatocytes: 49.7;Spermatogonia: 44.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 11.3;granulocytes: 31.4;monocytes: 17.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026404, HPA042433, HPA074225" Supported Approved Cytosol "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" Cytosol "CAB026404: , HPA042433: AB_2732499, HPA074225: " "unprognostic (3.16e-1)" "unprognostic (9.98e-2)" "unprognostic (4.03e-3)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (3.66e-4)" "unprognostic (4.15e-3)" "unprognostic (1.32e-1)" "unprognostic (4.84e-3)" "unprognostic (2.00e-1)" "unprognostic (3.53e-2)" "unprognostic (4.12e-3)" "unprognostic (4.24e-2)" "unprognostic (5.54e-2)" "unprognostic (3.59e-2)" "unprognostic (6.84e-2)" GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mucus glandular cells: 210.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" Enzyme NA NA 2600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 21: Non-specific - Metabolism" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA012628: AB_1849439" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" "unprognostic (2.08e-1)" "unprognostic (2.83e-2)" "unprognostic (1.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" "unprognostic (3.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (4.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.07e-2)" "unprognostic (8.60e-2)" GALNT10 GalNAc-T10 ENSG00000164574 "Polypeptide N-acetylgalactosaminyltransferase 10" Q86SR1 5 154190730-154420984 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 53.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 74.3;Granulosa cells: 94.2;Oligodendrocyte precursor cells: 147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007525 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" Enzyme NA NA 1100000 "Cluster 25: Non-specific - Unknown function" "Cluster 59: Fallopian tube - Tissue development" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA007525: AB_1849443" "unprognostic (6.99e-2)" "unprognostic (4.33e-2)" "unprognostic (9.85e-2)" "prognostic favorable (3.33e-6)" "unprognostic (1.63e-1)" "unprognostic (6.98e-2)" "unprognostic (6.95e-3)" "unprognostic (2.38e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (5.69e-4)" "unprognostic (2.88e-3)" "unprognostic (2.63e-1)" "unprognostic (1.54e-1)" "unprognostic (7.76e-3)" "unprognostic (1.22e-1)" "unprognostic (1.61e-2)" "unprognostic (3.08e-1)" GALNT12 GalNAc-T12 ENSG00000119514 "Polypeptide N-acetylgalactosaminyltransferase 12" Q8IXK2 9 98807670-98850081 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 73.0;intestine: 54.0;stomach 1: 53.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 77.1;Intestinal goblet cells: 141.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 59.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA048292, HPA071076" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" Enzyme NA NA 47000 "Cluster 22: Eosinophils - Transcription" "Cluster 53: Non-specific - Glycosylation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA048292: AB_2680343, HPA071076: " "unprognostic (7.85e-3)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.97e-3)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.61e-2)" "unprognostic (7.71e-2)" "prognostic favorable (3.24e-4)" "unprognostic (9.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-3)" "unprognostic (6.87e-2)" GALNT15 "GALNT7, GALNTL2, pp-GalNAc-T15" ENSG00000131386 "Polypeptide N-acetylgalactosaminyltransferase 15" Q8N3T1 3 16174680-16231992 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 110.1" "Cell type enhanced" "Detected in many" "Adipocytes: 102.8;Astrocytes: 32.8;Early spermatids: 29.3;Endothelial cells: 61.0;Fibroblasts: 51.9;Muller glia cells: 46.4;Oligodendrocytes: 64.5" "Cancer enriched" "Detected in many" 5 "glioma: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Macrophages, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017076 Uncertain Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA 40000 "Cluster 41: Basophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 13 "Golgi apparatus" Cytosol "HPA017076: AB_1849458" "unprognostic (3.87e-1)" "unprognostic (4.84e-4)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (7.40e-4)" "unprognostic (4.24e-1)" "unprognostic (2.24e-1)" "unprognostic (8.28e-6)" "unprognostic (5.13e-2)" "unprognostic (2.58e-1)" "unprognostic (2.66e-2)" "unprognostic (1.37e-3)" "unprognostic (1.88e-1)" "unprognostic (8.51e-2)" "unprognostic (1.78e-3)" GALNT2 GalNAc-T2 ENSG00000143641 "Polypeptide N-acetylgalactosaminyltransferase 2" Q10471 1 230057990-230282122 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 141.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011222 Supported Supported "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 13000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 77: Plasma cells - Protein processing" 5 "Golgi apparatus" "HPA011222: AB_1849446" "unprognostic (1.26e-1)" "prognostic unfavorable (1.22e-6)" "unprognostic (1.15e-2)" "unprognostic (1.35e-2)" "unprognostic (8.70e-3)" "unprognostic (7.77e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (8.48e-8)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (1.70e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.79e-13)" "unprognostic (3.79e-3)" "unprognostic (1.49e-1)" "unprognostic (3.64e-2)" "unprognostic (1.89e-1)" GALNT6 GalNAc-T6 ENSG00000139629 "Polypeptide N-acetylgalactosaminyltransferase 6" Q8NCL4 12 51351247-51392867 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.0;stomach 1: 60.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.0;Gastric mucus-secreting cells: 116.1;granulocytes: 95.6;Oligodendrocytes: 53.6;Serous glandular cells: 100.2" "Cancer enhanced" "Detected in many" "breast cancer: 31.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 29.2" "Group enriched" "Detected in all" 4 "granulocytes: 29.2;monocytes: 9.8;NK-cells: 15.7" "Cancer enhanced" "Detected in many" "breast cancer: 56.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011762, HPA017086" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 4800000 "Cluster 45: Eosinophils - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 2 "Nucleoplasm, Golgi apparatus" "HPA011762: AB_1849450, HPA017086: AB_1849452" "unprognostic (2.03e-1)" "unprognostic (6.65e-2)" "unprognostic (2.26e-2)" "prognostic favorable (9.85e-4)" "unprognostic (1.35e-2)" "unprognostic (1.18e-1)" "unprognostic (7.15e-3)" "unprognostic (2.05e-1)" "unprognostic (2.27e-2)" "prognostic favorable (5.40e-4)" "unprognostic (1.88e-2)" "unprognostic (5.25e-2)" "unprognostic (7.13e-4)" "unprognostic (5.65e-3)" "unprognostic (3.18e-1)" "unprognostic (2.16e-2)" "unprognostic (1.18e-2)" GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 30.2;testis: 13.1" "Group enriched" "Detected in some" 4 "Early spermatids: 36.0;Intestinal goblet cells: 38.3;Late spermatids: 99.3" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.2;glioma: 1.8;pancreatic cancer: 0.8;testis cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.6" "Breast - Fibroblasts, Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA No "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 63: Late spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: AB_2686604" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" GALNTL6 "GalNAc-T6L, GALNT17" ENSG00000174473 "Polypeptide N-acetylgalactosaminyltransferase like 6" Q49A17 4 171812254-173041559 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.0;lymphoid tissue: 2.5;testis: 2.4" "Group enriched" "Detected in some" 17 "Excitatory neurons: 410.5;Inhibitory neurons: 1496.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 8 "B-cells: 1.6" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.6" "Skin - Melanocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031019 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 69: Neurons - Neuronal signaling" "HPA031019: AB_10601653" "unprognostic (6.84e-2)" "unprognostic (1.28e-1)" "unprognostic (2.01e-2)" "unprognostic (5.73e-2)" "unprognostic (7.50e-2)" "unprognostic (8.32e-2)" "unprognostic (3.25e-1)" "unprognostic (9.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (2.80e-1)" "unprognostic (1.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-2)" "unprognostic (4.84e-3)" "unprognostic (1.73e-2)" GALP ENSG00000197487 "Galanin like peptide" Q9UBC7 19 56176008-56185775 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Hormone, Neuropeptide" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Glandular and luminal cells: 1.1" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053938 Uncertain "Secreted in brain" Hormone NA NA "Cluster 1: Neuronal - Visual perception" "Cluster 37: Glandular & Luminal cells - Unknown function" 2 "HPA053938: AB_2682315" "unprognostic (8.51e-3)" "unprognostic (1.22e-2)" "unprognostic (2.65e-1)" "unprognostic (7.02e-2)" GANAB "G2AN, GIIA, GluII, KIAA0088" ENSG00000089597 "Glucosidase II alpha subunit" Q14697 11 62624826-62646726 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026874, HPA061426" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 23000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 4: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum" "HPA026874: AB_1849745, HPA061426: AB_2684516" "unprognostic (2.12e-1)" "unprognostic (5.95e-3)" "unprognostic (4.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (5.80e-3)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.01e-3)" "unprognostic (3.81e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.54e-4)" GARS1 "CMT2D, DSMAV, GARS, GlyRS, SMAD1" ENSG00000106105 "Glycyl-tRNA synthetase 1" P41250 7 30580533-30634033 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Hydrolase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017896, HPA019097" Enhanced Supported Cytosol "Intracellular and membrane" Enzyme NA NA 560000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 39: Non-specific - Basic cellular processes" 4 Cytosol "HPA017896: AB_1849478, HPA019097: AB_1849480" "prognostic unfavorable (1.02e-4)" "unprognostic (2.46e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (2.04e-1)" "unprognostic (1.57e-3)" "prognostic unfavorable (8.95e-5)" "unprognostic (7.31e-3)" "unprognostic (4.76e-1)" "unprognostic (4.00e-3)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "prognostic unfavorable (1.70e-5)" "unprognostic (3.92e-1)" "unprognostic (3.40e-2)" "unprognostic (6.32e-2)" "prognostic unfavorable (3.04e-5)" GAS6 "AXLLG, AXSF, DKFZp666G247, FLJ34709" ENSG00000183087 "Growth arrest specific 6" Q14393 13 113820549-113864076 "Predicted secreted proteins" "Growth regulation, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 295.4;Granulosa cells: 427.0;Secretory cells: 550.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 70.8" "Lineage enriched" "Detected in many" 50 "dendritic cells: 70.8" "Cancer enhanced" "Detected in all" "Bile duct cancer: 260.5" "Breast - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008275, HPA056080" Approved Approved "Centriolar satellite,Cytosol" "Secreted to blood" Other NA NA 8900000 3600000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Cytosol "Centriolar satellite" "HPA008275: AB_1849497, HPA056080: AB_2683032" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.97e-3)" "unprognostic (1.37e-1)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (2.92e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.55e-1)" "unprognostic (4.81e-3)" "unprognostic (1.97e-1)" "unprognostic (2.16e-2)" "unprognostic (9.00e-2)" "prognostic unfavorable (8.93e-6)" GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979087-43067898 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 79.9;Hepatocytes: 17.8;Microglial cells: 18.8;Oligodendrocyte precursor cells: 21.2;Peritubular cells: 18.7" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.0;Neuroblastoma: 1.9" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" "No annotated function" NA NA 600000 "Cluster 64: Neuronal - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 47: Astrocytes - Unknown function" Vesicles "HPA047726: AB_10960554" "unprognostic (2.16e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.93e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.57e-4)" "unprognostic (4.45e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" GAST GAS ENSG00000184502 Gastrin P01350 17 41712331-41715969 "Cancer-related genes, FDA approved drug targets, Predicted secreted proteins" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "stomach 1: 9294.1" "Group enriched" "Detected in some" 4 "Glandular and luminal cells: 105.4;Plasma cells: 56.3" "Group enriched" "Detected in many" 6 "pancreatic cancer: 38.8;stomach cancer: 23.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 2.8;colorectal cancer: 2.5;Esophageal cancer: 4.6;Gastric cancer: 9.0;head and neck cancer: 5.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" CAB000038 Enhanced "Secreted to digestive system" Hormone NA NA 87000 "Cluster 48: Stomach - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Plasma cells - Humoral immune response" 18 "CAB000038: " "unprognostic (1.27e-1)" "unprognostic (4.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "unprognostic (2.75e-2)" "unprognostic (5.68e-2)" "unprognostic (2.11e-1)" "unprognostic (2.85e-1)" "unprognostic (3.17e-1)" "unprognostic (9.07e-2)" GATD1 "FLJ34283, PDDC1" ENSG00000177225 "Glutamine amidotransferase class 1 domain containing 1" Q8NB37 11 767220-777488 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008812 Uncertain Supported Nucleoplasm "Secreted to blood" "No annotated function" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" Nucleoplasm "HPA008812: AB_10962724" "unprognostic (3.39e-1)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" "unprognostic (3.58e-2)" "unprognostic (2.82e-2)" "unprognostic (3.03e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (3.50e-2)" "unprognostic (2.19e-1)" "unprognostic (5.67e-2)" "unprognostic (5.23e-3)" "unprognostic (4.89e-3)" "prognostic favorable (3.79e-5)" "unprognostic (2.84e-2)" "unprognostic (8.40e-2)" "unprognostic (6.11e-2)" "unprognostic (6.61e-3)" GATD3 "C21orf33, D21S2048E, ES1, GATD3A, GT335, HES1, KNP-I, KNP-Ia, KNPH, KNPI" ENSG00000160221 "Glutamine amidotransferase class 1 domain containing 3" P0DPI2 21 44133610-44210114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 367.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 27.5;Enteroendocrine cells: 21.5;Undifferentiated cells: 25.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018517 Enhanced Approved Centrosome,Mitochondria "Intracellular and membrane" "No annotated function" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 16: Intestinal goblet cells - Mucin production" Mitochondria Centrosome "HPA018517: AB_2669899" "unprognostic (9.61e-3)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (3.80e-2)" "unprognostic (1.54e-3)" "unprognostic (6.57e-2)" "unprognostic (8.19e-2)" "unprognostic (1.36e-2)" "unprognostic (8.61e-3)" "unprognostic (9.43e-2)" "unprognostic (4.60e-3)" "unprognostic (1.97e-3)" "unprognostic (1.40e-1)" "unprognostic (6.96e-2)" "unprognostic (1.30e-2)" GBA1 "GBA, GLUC" ENSG00000177628 "Glucosylceramidase beta 1" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 15.3;Schwann cells: 13.4;Syncytiotrophoblasts: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" Enzyme NA NA 470000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" GBGT1 "A3GALNT, FS, MGC44848, UDP-GalNAc" ENSG00000148288 "Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group)" Q8N5D6 9 133152948-133163933 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 21.7;Kupffer cells: 22.4;Macrophages: 17.0;monocytes: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 8 "Leukemia: 27.2" "Adipose subcutaneous - Macrophages, Skeletal muscle - Macrophages, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051298 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Macrophages - Innate immune response" "HPA051298: AB_2681428" "unprognostic (4.63e-3)" "unprognostic (8.03e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (2.70e-1)" "unprognostic (8.87e-2)" "unprognostic (4.38e-1)" "unprognostic (2.97e-2)" "unprognostic (7.43e-2)" "unprognostic (9.04e-2)" "unprognostic (2.27e-3)" "unprognostic (2.35e-1)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.46e-5)" "unprognostic (2.92e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-2)" "unprognostic (6.35e-2)" GBP1 ENSG00000117228 "Guanylate binding protein 1" P32455 1 89051882-89065360 "Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 85.5" "Cell type enhanced" "Detected in many" "monocytes: 108.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - NK-cells (Lung)" "Low region specificity" "Detected in all" CAB015450 Approved "Intracellular and membrane" Immunity NA NA 110000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Liver - Plasma proteins" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 58: Macrophages - Innate immune response" 4 "CAB015450: AB_2109333" "unprognostic (3.43e-2)" "unprognostic (1.82e-2)" "prognostic favorable (8.32e-4)" "unprognostic (9.56e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (9.50e-2)" "unprognostic (3.64e-2)" "unprognostic (7.67e-2)" "prognostic favorable (5.04e-4)" "unprognostic (8.36e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (5.12e-9)" "unprognostic (4.67e-2)" "unprognostic (4.17e-2)" "unprognostic (2.23e-2)" "unprognostic (2.01e-3)" GC "DBP, hDBP, VDBP" ENSG00000145321 "GC vitamin D binding protein" P02774 4 71741696-71804041 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" Transport Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 8007.3" "Group enriched" "Detected in some" 9 "Cholangiocytes: 1684.6;Hepatocytes: 2766.0" "Cancer enriched" "Detected in many" 18 "liver cancer: 1016.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "liver cancer: 29.9" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001526, CAB008596, HPA019855" Supported "Secreted to blood" Transport NA NA 143000000000 73000000000 "Cluster 83: Liver - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "CAB008596: AB_1622398, HPA001526: AB_1078959, HPA019855: AB_1849545" "prognostic favorable (8.08e-4)" "unprognostic (1.06e-3)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.55e-1)" "unprognostic (2.15e-1)" GCG "GLP-1, GLP1, GLP2, GRPP" ENSG00000115263 Glucagon P01275 2 162142882-162152404 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "pancreas: 1880.7" "Group enriched" "Detected in some" 166 "Enteroendocrine cells: 3659.8;Pancreatic endocrine cells: 5805.4" "Cancer enriched" "Detected in some" 209 "pancreatic cancer: 428.4" "Region enriched" "Detected in single" 51 "medulla oblongata: 13.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 114.8;Rhabdoid: 411.9" "Colon - Colon enterocytes, Pancreas - Alpha cells" "Region enriched" "Detected in single" 10 "pons and medulla: 3.5" "Region enriched" "Detected in some" 5 "spinal cord: 18.2" "CAB000040, HPA036760, HPA036761" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" Hormone NA NA 127000 420000 "Cluster 15: Pancreas - Proteolysis" "Cluster 43: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 "Endoplasmic reticulum" Vesicles "CAB000040: AB_10013726, HPA036760: AB_2675296, HPA036761: AB_2675297" "unprognostic (3.13e-3)" "unprognostic (9.99e-2)" "unprognostic (1.16e-2)" "unprognostic (1.26e-2)" GCSH ENSG00000140905 "Glycine cleavage system protein H" P23434 16 81081945-81096395 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 136.2" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 500.6;Extravillous trophoblasts: 1279.9;Proximal tubular cells: 488.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041368, HPA057079" Supported Approved Vesicles "Intracellular and membrane" "No annotated function" NA NA 50000 "Cluster 30: Non-specific - DNA binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 4: Extravillous trophoblasts - Unknown function" 6 Vesicles "HPA041368: AB_10804001, HPA057079: " "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (2.47e-3)" "unprognostic (2.55e-3)" "unprognostic (4.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.96e-2)" "unprognostic (6.92e-2)" "unprognostic (2.80e-2)" "prognostic favorable (6.26e-6)" "unprognostic (1.12e-2)" "unprognostic (2.59e-1)" "unprognostic (6.31e-2)" "unprognostic (6.47e-2)" GDF1 ENSG00000130283 "Growth differentiation factor 1" P27539 19 18868545-18896158 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 45.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" Cytokine NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.0;retina: 17.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 19.0;Cone photoreceptor cells: 10.2;Fibroblasts: 25.6;Horizontal cells: 7.6;Lymphatic endothelial cells: 8.4;Rod photoreceptor cells: 27.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "Bone cancer: 13.5" "Breast - Fibroblasts, Skin - Fibroblast_2, Testis - Sertoli cells, Thyroid - Fibroblasts" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" Cytokine NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" GDF11 "BMP-11, BMP11" ENSG00000135414 "Growth differentiation factor 11" O95390 12 55743122-55757264 "Disease related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 21.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 68.3;Cone photoreceptor cells: 57.8;Horizontal cells: 41.5;Rod photoreceptor cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060985, HPA069609" Approved Approved Vesicles "Secreted to blood" Cytokine No No 46400 340000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 17: Neuronal - Synaptic function" "Cluster 46: Brainstem - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 25: Bipolar cells - Visual perception" Vesicles "HPA060985: AB_2684403, HPA069609: AB_2686159" "unprognostic (5.21e-2)" "unprognostic (1.62e-1)" "unprognostic (3.20e-2)" "unprognostic (2.41e-2)" "unprognostic (2.78e-2)" "unprognostic (3.39e-1)" "unprognostic (2.13e-1)" "unprognostic (2.62e-2)" "unprognostic (8.96e-3)" "unprognostic (1.23e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.69e-1)" "unprognostic (1.62e-2)" "unprognostic (1.27e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" "unprognostic (9.48e-2)" GDF15 "MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB" ENSG00000130513 "Growth differentiation factor 15" Q99988 19 18374731-18389176 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 361.6;urinary bladder: 169.9" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 4930.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 9 "choroid plexus: 72.0" "Immune cell enhanced" "Detected in some" "neutrophil: 2.5" "Group enriched" "Detected in many" 4 "granulocytes: 2.5;monocytes: 1.1" "Cancer enhanced" "Detected in many" "prostate cancer: 802.0;skin cancer: 1117.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA011191, CAB062554, HPA070957" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" Cytokine NA NA 1260000 960000 "Cluster 21: Neutrophils - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Respiratory epithelial cells - Unknown function" 5 "Golgi apparatus" "CAB062554: AB_2665632, HPA011191: AB_1078962, HPA070957: AB_2732168" "unprognostic (1.04e-1)" "unprognostic (1.89e-2)" "unprognostic (3.45e-2)" "unprognostic (3.36e-2)" "unprognostic (2.04e-2)" "unprognostic (2.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.30e-2)" "unprognostic (2.80e-1)" "unprognostic (2.89e-1)" "unprognostic (5.09e-2)" "unprognostic (1.46e-1)" "unprognostic (6.55e-3)" "unprognostic (3.81e-2)" "unprognostic (8.45e-2)" "unprognostic (1.25e-1)" "unprognostic (3.04e-3)" GDF2 "BMP-9, BMP9" ENSG00000263761 "Growth differentiation factor 2" Q9UK05 10 47322454-47327588 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Angiogenesis "Cytokine, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 134 "liver: 18.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatic stellate cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB023357 Uncertain "Secreted to blood" Cytokine NA NA 2210000 740000 "Cluster 31: Liver - Plasma proteins" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "CAB023357: AB_2111086" GDF3 ENSG00000184344 "Growth differentiation factor 3" Q9NR23 12 7689784-7695775 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "kidney: 2.8" "Group enriched" "Detected in some" 6 "Endothelial cells: 2.2;Granulosa cells: 1.7;Lymphatic endothelial cells: 6.1" "Cancer enriched" "Detected in some" 422 "testis cancer: 383.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 111 "testis cancer: 71.1" "Kidney - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA018468 Uncertain "Secreted to blood" Cytokine NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 34: Testis cancer - Unknown function" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "HPA018468: AB_1849586" "unprognostic (9.48e-2)" "unprognostic (3.90e-2)" "unprognostic (3.30e-2)" "unprognostic (1.86e-2)" "unprognostic (3.51e-1)" "unprognostic (5.40e-2)" "unprognostic (3.09e-1)" "unprognostic (2.08e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" "unprognostic (9.20e-2)" "unprognostic (1.25e-3)" "unprognostic (8.00e-3)" "unprognostic (1.00e-1)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" GDF5 "BMP14, CDMP1" ENSG00000125965 "Growth differentiation factor 5" P43026 20 35433347-35454746 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Chondrogenesis "Cytokine, Growth factor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "salivary gland: 9.6" "Cell type enhanced" "Detected in some" "Mesothelial cells: 1.9;Mucus glandular cells: 8.1;Serous glandular cells: 5.2" "Cancer enriched" "Detected in single" 7 "endometrial cancer: 3.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 12.4" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA015648 Uncertain "Secreted to blood" Cytokine NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 72: Neuronal - Signal transduction" "Cluster 75: Serous glandular cells - Salivary secretion" 2 "HPA015648: AB_1849589" "unprognostic (4.59e-3)" "unprognostic (3.48e-2)" "unprognostic (5.53e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (1.53e-2)" "unprognostic (4.64e-1)" "unprognostic (2.17e-3)" "unprognostic (4.38e-2)" "unprognostic (1.40e-1)" "unprognostic (8.02e-2)" "unprognostic (2.77e-1)" "unprognostic (5.57e-3)" "unprognostic (2.13e-2)" "unprognostic (1.24e-1)" "unprognostic (1.38e-1)" "unprognostic (8.96e-3)" GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Deafness, Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 3.1;Fibroblasts: 2.2;Mesothelial cells: 2.8;Oligodendrocyte precursor cells: 6.6;Oocytes: 2.2;Pancreatic endocrine cells: 1.7;Spermatogonia: 2.1" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 31.8;Neuroblastoma: 10.7;Sarcoma: 11.2;testis cancer: 14.6" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 2.0" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" Cytokine NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" GDF7 BMP12 ENSG00000143869 "Growth differentiation factor 7" Q7Z4P5 2 20667144-20679243 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 9.5;seminal vesicle: 21.7" "Cell type enriched" "Detected in some" 14 "Endometrial stromal cells: 121.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.4" "Adipose subcutaneous - Smooth muscle cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA069106 Approved Vesicles "Secreted in other tissues" Cytokine NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 9: Endometrial stromal cells - Transcription" Vesicles "HPA069106: " "unprognostic (1.35e-1)" "unprognostic (9.93e-3)" "unprognostic (5.10e-1)" "unprognostic (2.44e-3)" "unprognostic (1.35e-1)" "unprognostic (2.06e-3)" "unprognostic (8.63e-3)" "unprognostic (6.31e-3)" "unprognostic (8.00e-3)" "unprognostic (3.85e-1)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.28e-3)" "unprognostic (8.02e-3)" "unprognostic (2.05e-1)" "unprognostic (3.44e-2)" "unprognostic (1.89e-3)" GDF9 ENSG00000164404 "Growth differentiation factor 9" O60383 5 132861181-132866884 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.7" "Cell type enriched" "Detected in some" 5 "Oocytes: 155.9" "Cancer enriched" "Detected in some" 5 "breast cancer: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069146 Supported Approved "Golgi apparatus,Cytosol" "Secreted in female reproductive system" Cytokine NA NA "Cluster 63: Testis - Spermatid development" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 44: Oocytes - Unknown function" 3 "Golgi apparatus" Cytosol "HPA069146: AB_2686094" "unprognostic (4.64e-1)" "unprognostic (1.22e-1)" "unprognostic (1.25e-2)" "unprognostic (5.11e-2)" "unprognostic (1.58e-2)" "unprognostic (2.39e-2)" "unprognostic (1.55e-1)" "unprognostic (4.61e-2)" "unprognostic (4.88e-2)" "unprognostic (1.68e-1)" "unprognostic (6.70e-3)" "unprognostic (1.04e-1)" "unprognostic (1.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (4.75e-3)" "unprognostic (3.10e-2)" GDNF "ATF1, ATF2, HFB1-GDNF" ENSG00000168621 "Glial cell derived neurotrophic factor" P39905 5 37812677-37840041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes, Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7.9;skeletal muscle: 9.7" "Cell type enriched" "Detected in some" 43 "Skeletal myocytes: 108.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 20.0" "Heart muscle - Fibroblasts" "Region enhanced" "Detected in single" "basal ganglia: 2.8" "Low region specificity" "Detected in some" "CAB005210, HPA070283" Supported Approved Nucleoplasm,Vesicles "Secreted in other tissues" "Growth factor" NA NA "Cluster 79: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" 1 Vesicles Nucleoplasm "CAB005210: AB_2247684, HPA070283: AB_2686246" "unprognostic (1.08e-1)" "unprognostic (6.30e-2)" "unprognostic (3.54e-2)" "unprognostic (8.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (5.33e-2)" "unprognostic (1.92e-1)" "unprognostic (3.71e-2)" "unprognostic (2.01e-2)" "unprognostic (2.41e-1)" "unprognostic (2.10e-1)" "unprognostic (1.16e-4)" "unprognostic (2.04e-1)" "unprognostic (8.86e-2)" "unprognostic (1.05e-1)" "unprognostic (4.42e-2)" GFER "ALR, ERV1, HERV1, HPO1, HPO2, HSS" ENSG00000127554 "Growth factor, augmenter of liver regeneration" P55789 16 1984193-1987749 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Oxidoreductase" "Cataract, Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 170.5;Late spermatids: 156.0;Proximal enterocytes: 393.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041227, HPA063553" Approved Enhanced Mitochondria,Cytosol "Secreted to blood" "Growth factor" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 5 Cytosol Mitochondria "HPA041227: AB_10795538, HPA063553: AB_2685038" "unprognostic (5.35e-2)" "unprognostic (2.11e-2)" "unprognostic (3.08e-1)" "unprognostic (4.42e-2)" "unprognostic (3.15e-1)" "unprognostic (2.63e-1)" "unprognostic (1.27e-2)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.56e-1)" "unprognostic (5.93e-2)" "prognostic favorable (4.06e-4)" "unprognostic (4.93e-2)" "unprognostic (3.64e-1)" "unprognostic (3.56e-1)" "unprognostic (1.09e-2)" GFOD1 "ADG-90, C6orf114, FLJ20330" ENSG00000145990 "Glucose-fructose oxidoreductase domain containing 1" Q9NXC2 6 13357830-13487662 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 98.1;Excitatory neurons: 128.8;Inhibitory neurons: 101.8;monocytes: 163.5;NK-cells: 113.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 15.5;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 15.5;NK-cells: 13.1" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029096 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted - unknown location" Enzyme No No "Cluster 45: Eosinophils - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 17 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029096: AB_10602320" "unprognostic (5.00e-2)" "unprognostic (1.34e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.29e-5)" "unprognostic (8.49e-2)" "unprognostic (1.95e-3)" "unprognostic (1.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.34e-2)" "unprognostic (3.11e-2)" "unprognostic (6.49e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.72e-5)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (4.66e-3)" GFOD2 "FLJ23802, MGC11335" ENSG00000141098 "Glucose-fructose oxidoreductase domain containing 2" Q3B7J2 16 67674531-67719339 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 56.1" "Cell type enhanced" "Detected in all" "Early spermatids: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040939, HPA041112" Uncertain Supported Nucleoplasm,Cytosol "Secreted to blood" Enzyme NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 35: Non-specific - DNA binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 13: Spermatids - Transcription" Nucleoplasm Cytosol "HPA040939: AB_10796564, HPA041112: AB_10794541" "unprognostic (9.80e-2)" "unprognostic (2.20e-1)" "unprognostic (2.06e-2)" "unprognostic (3.16e-3)" "unprognostic (4.62e-2)" "unprognostic (1.38e-1)" "unprognostic (2.93e-2)" "unprognostic (5.61e-3)" "unprognostic (1.19e-1)" "unprognostic (2.22e-2)" "prognostic favorable (5.95e-4)" "unprognostic (1.17e-1)" "prognostic favorable (8.66e-4)" "unprognostic (1.90e-1)" "unprognostic (1.76e-1)" "unprognostic (7.87e-2)" "unprognostic (9.64e-2)" GFRA2 "GDNFRB, NTNRA, RETL2, TRNR2" ENSG00000168546 "GDNF family receptor alpha 2" O00451 8 21690398-21812357 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.2;thyroid gland: 8.4" "Cell type enriched" "Detected in some" 4 "Late spermatids: 263.4" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 9.3" "Group enriched" "Detected in many" 7 "dendritic cells: 2.5;monocytes: 9.3" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 59.7" "Liver - Kupffer cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024704, CAB032791" Uncertain Approved "Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA 9000000 "Cluster 25: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Late spermatids - Unknown function" "Plasma membrane" Vesicles "CAB032791: AB_2110428, HPA024704: AB_1849629" "unprognostic (4.24e-2)" "unprognostic (1.11e-2)" "unprognostic (4.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.93e-2)" "unprognostic (1.08e-2)" "unprognostic (7.48e-4)" "unprognostic (2.87e-1)" "unprognostic (6.11e-2)" "unprognostic (4.40e-3)" "unprognostic (2.11e-3)" "unprognostic (7.82e-2)" "unprognostic (1.50e-4)" "unprognostic (8.45e-4)" "unprognostic (1.74e-1)" "unprognostic (4.68e-2)" "unprognostic (9.63e-3)" GFRA4 ENSG00000125861 "GDNF family receptor alpha 4" Q9GZZ7 20 3659248-3663399 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "thyroid gland: 1.0" "Cell type enhanced" "Detected in some" "Early spermatids: 1.5;Late spermatids: 2.9;Proximal tubular cells: 1.6" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 96 "thyroid cancer: 10.0" "Thyroid - Parafollicular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 38: Proximal tubular cells - Transmembrane transport" "unprognostic (3.50e-2)" "unprognostic (2.36e-1)" GGA2 "KIAA1080, VEAR" ENSG00000103365 "Golgi associated, gamma adaptin ear containing, ARF binding protein 2" Q9UJY4 16 23463542-23521995 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034422, HPA043313, HPA063634" Approved Enhanced "Golgi apparatus" "Intracellular and membrane" Transport NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 16: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 12 "Golgi apparatus" "CAB034422: AB_2110748, HPA043313: AB_2678421, HPA063634: AB_2685067" "unprognostic (1.27e-1)" "prognostic favorable (1.71e-5)" "unprognostic (8.53e-2)" "unprognostic (2.22e-2)" "unprognostic (4.91e-2)" "prognostic favorable (9.70e-5)" "unprognostic (1.68e-1)" "prognostic favorable (1.68e-4)" "unprognostic (7.82e-3)" "unprognostic (3.88e-2)" "unprognostic (2.15e-3)" "unprognostic (8.55e-2)" "prognostic favorable (3.91e-5)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.15e-4)" "unprognostic (3.89e-2)" "unprognostic (2.08e-1)" GGH GATD10 ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63014881-63039407 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 121.2;liver: 183.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 518.4;Early spermatids: 371.7;Extravillous trophoblasts: 309.4;Late spermatids: 258.6;Oocytes: 235.3;Syncytiotrophoblasts: 725.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 30.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 30.6" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved "Intracellular and membrane" Enzyme NA NA 1200000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 24: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "CAB019296: , HPA025226: AB_1849645" "unprognostic (9.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.99e-7)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (1.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-2)" "unprognostic (9.62e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 173.5;liver: 113.1" "Group enriched" "Detected in some" 4 "Distal enterocytes: 23.8;Ductal cells: 57.7;Exocrine glandular cells: 30.0;Proximal enterocytes: 49.9" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 119.6" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA 3600000 "Cluster 28: Neutrophils - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 33.9;Endothelial cells: 47.8;Fibroblasts: 69.3;Leydig cells: 33.4;Lymphatic endothelial cells: 78.8;Sertoli cells: 87.0;Smooth muscle cells: 87.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3;eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Cancer enhanced" "Detected in many" "testis cancer: 62.1" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" Enzyme NA NA 22000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (6.36e-5)" "prognostic unfavorable (4.06e-4)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" GH1 "GH, GH-N, GHN, hGH-N" ENSG00000259384 "Growth hormone 1" P01241 17 63917200-63918839 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 869 "pituitary gland: 57767.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043715 Supported "Secreted to blood" Hormone NA NA 2690000 6400000 "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 1 "HPA043715: AB_2678632" "unprognostic (1.91e-2)" "unprognostic (3.51e-2)" "unprognostic (1.72e-2)" "unprognostic (2.98e-1)" "unprognostic (9.45e-4)" "unprognostic (2.48e-1)" "unprognostic (2.09e-4)" "unprognostic (2.03e-2)" "unprognostic (6.57e-2)" "unprognostic (2.33e-1)" GH2 "GH-V, GHL, GHV, hGH-V" ENSG00000136487 "Growth hormone 2" P01242 17 63880215-63881944 "Cancer-related genes, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 79 "pituitary gland: 99.7;placenta: 123.9" "Group enriched" "Detected in some" 29 "Extravillous trophoblasts: 9.9;Syncytiotrophoblasts: 34.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "testis cancer: 1.1" HPA043715 Supported "Secreted to blood" Hormone NA NA 4200000 "Cluster 58: Placenta - Pregnancy" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA043715: AB_2678632" "unprognostic (1.02e-1)" GHDC LGP1 ENSG00000167925 "GH3 domain containing" Q8N2G8 17 42188799-42194532 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031650 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 47: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA031650: AB_10601014" "unprognostic (2.30e-2)" "unprognostic (1.63e-1)" "unprognostic (2.60e-1)" "prognostic favorable (3.21e-4)" "prognostic unfavorable (6.81e-5)" "unprognostic (5.13e-2)" "unprognostic (3.35e-2)" "unprognostic (2.56e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (5.20e-4)" "unprognostic (6.69e-3)" "unprognostic (5.18e-2)" "prognostic favorable (2.00e-6)" "unprognostic (2.08e-1)" "unprognostic (7.93e-2)" "unprognostic (9.66e-2)" "unprognostic (4.02e-2)" GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 81.8;liver: 206.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.2;Hepatocytes: 119.8;Inhibitory neurons: 111.4;Oligodendrocyte precursor cells: 169.8;Syncytiotrophoblasts: 46.6" "Group enriched" "Detected in many" 4 "breast cancer: 2.8;liver cancer: 7.6;prostate cancer: 8.1;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" Receptor NA NA 2200000 24000000 "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 8: Neurons - Neuronal signaling" 9 "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: AB_2679294, HPA057705: AB_2683507" "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" GHRH GHRF ENSG00000118702 "Growth hormone releasing hormone" P01286 20 37251086-37261819 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 47.4" "Cell type enriched" "Detected in single" 10 "Cardiomyocytes: 7.0" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 8.5" "Region enriched" "Detected in single" 542 "hypothalamus: 428.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 72 "lung cancer: 28.6" "Region enriched" "Detected in many" 9 "hypothalamus: 32.9" "Region enhanced" "Detected in some" "hypothalamus: 4.9" "Secreted in other tissues" "No annotated function" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 68: Cardiomyocytes - Muscle contraction" "unprognostic (4.78e-2)" "unprognostic (2.57e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-1)" GHRHR ENSG00000106128 "Growth hormone releasing hormone receptor" Q02643 7 30938669-30993254 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 351 "pituitary gland: 206.1" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Spermatocytes: 1.6;Spermatogonia: 2.6" "Cancer enhanced" "Detected in single" "liver cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "prostate cancer: 2.1" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Receptor NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 67: Spermatogonia - Spermatogenesis" "unprognostic (8.32e-2)" "unprognostic (1.45e-1)" "unprognostic (9.30e-2)" "unprognostic (1.39e-1)" "unprognostic (7.23e-2)" "unprognostic (4.15e-1)" "unprognostic (2.28e-2)" "unprognostic (1.54e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (1.43e-2)" "unprognostic (1.47e-1)" "unprognostic (5.87e-3)" GHRL "ghrelin, MTLRP, obestatin" ENSG00000157017 "Ghrelin and obestatin prepropeptide" Q9UBU3 3 10285666-10292947 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "stomach 1: 346.3" "Cell type enriched" "Detected in many" 73 "Gastric mucus-secreting cells: 1282.9" "Cancer enhanced" "Detected in some" "stomach cancer: 3.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 17.6;classical monocyte: 11.1;eosinophil: 12.4;myeloid DC: 41.9;neutrophil: 25.9;plasmacytoid DC: 28.6" "Group enriched" "Detected in many" 6 "dendritic cells: 41.9;granulocytes: 25.9;monocytes: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA014246, CAB022731" Enhanced "Secreted to blood" Hormone NA NA 2580000 350000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 46: Gastric mucus-secreting cells - Digestion" 2 "CAB022731: , HPA014246: AB_1849659" "unprognostic (1.74e-2)" "unprognostic (3.01e-4)" "unprognostic (3.75e-1)" "unprognostic (1.05e-2)" "unprognostic (2.94e-2)" "unprognostic (1.60e-3)" "unprognostic (2.12e-1)" "unprognostic (1.06e-3)" "unprognostic (3.85e-1)" "unprognostic (5.45e-3)" "unprognostic (1.54e-3)" "unprognostic (2.71e-2)" "unprognostic (1.64e-3)" "unprognostic (4.52e-2)" "unprognostic (8.56e-2)" "unprognostic (2.14e-1)" "unprognostic (1.79e-4)" GIP ENSG00000159224 "Gastric inhibitory polypeptide" P09681 17 48958554-48968596 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Hormone "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 208 "intestine: 251.8" "Cell type enriched" "Detected in single" 35 "Enteroendocrine cells: 19.5" "Cancer enriched" "Detected in some" 63 "testis cancer: 74.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021612, HPA064596" Enhanced "Secreted to blood" Hormone NA NA 33900 540000 "Cluster 25: Small intestine - Absorption" "Cluster 1: Neuronal - Visual perception" "Cluster 20: Enteroendocrine cells - Hormone signaling" 4 "HPA021612: AB_1849506, HPA064596: " "unprognostic (2.95e-1)" "unprognostic (2.70e-3)" "unprognostic (4.42e-2)" "unprognostic (1.82e-1)" GKN1 "AMP18, BRICD1, CA11" ENSG00000169605 "Gastrokine 1" Q9NS71 2 68974573-68980980 "Plasma proteins, Predicted secreted proteins, Transporters" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1856 "stomach 1: 36428.6" "Cell type enriched" "Detected in some" 518 "Gastric mucus-secreting cells: 8421.2" "Cancer enriched" "Detected in some" 116 "stomach cancer: 255.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 26 "Bladder cancer: 18.4" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA047684 Enhanced "Secreted to digestive system" Other NA NA 18000000 "Cluster 48: Stomach - Proteolysis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Gastric mucus-secreting cells - Digestion" 13 "HPA047684: AB_2680120" "unprognostic (5.40e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.54e-1)" "prognostic favorable (4.53e-4)" GKN2 "blottin, BRICD1B, GDDR, PRO813, TFIZ1, VLTI465" ENSG00000183607 "Gastrokine 2" Q86XP6 2 68945232-68952893 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "stomach 1: 4488.5" "Cell type enriched" "Detected in some" 5 "Gastric mucus-secreting cells: 2368.8" "Cancer enriched" "Detected in some" 8 "stomach cancer: 43.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ovarian cancer: 3.0;pancreatic cancer: 4.6;prostate cancer: 1.8;thyroid cancer: 4.3" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA057765 Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 46: Gastric mucus-secreting cells - Digestion" 1 "HPA057765: AB_2683520" "unprognostic (1.81e-1)" "unprognostic (1.44e-4)" "unprognostic (2.22e-1)" GLA GALA ENSG00000102393 "Galactosidase alpha" P06280 X 101393273-101408012 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 457.1;Plasma cells: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000237, HPA000966" Enhanced "Intracellular and membrane" Enzyme NA NA 1300000 "Cluster 40: Monocytes - Innate immune response" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 80: Non-specific - Transcription" 1 "HPA000237: AB_1078968, HPA000966: AB_1078969" "unprognostic (7.27e-3)" "unprognostic (1.47e-2)" "unprognostic (1.57e-2)" "unprognostic (2.94e-1)" "unprognostic (1.60e-1)" "unprognostic (3.15e-2)" "prognostic unfavorable (5.62e-5)" "unprognostic (2.53e-1)" "unprognostic (3.42e-1)" "unprognostic (1.89e-1)" "unprognostic (2.97e-2)" "unprognostic (3.27e-2)" "unprognostic (2.73e-2)" "prognostic favorable (6.16e-4)" "unprognostic (1.13e-1)" "unprognostic (5.44e-2)" "unprognostic (2.21e-1)" GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts, Colon - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 2700000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 34: Testis cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" 6 Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" GLB1L MGC10771 ENSG00000163521 "Galactosidase beta 1 like" Q6UWU2 2 219236598-219245478 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 50.8" "Cell type enhanced" "Detected in many" "Early spermatids: 52.1;Spermatocytes: 99.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043058 Enhanced "Secreted - unknown location" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 3: Choroid plexus - Cilium" "Cluster 69: Skin cancer - ECM organization" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA043058: AB_10806375" "unprognostic (4.30e-2)" "unprognostic (6.93e-2)" "unprognostic (2.68e-2)" "unprognostic (2.08e-3)" "unprognostic (4.35e-2)" "unprognostic (1.51e-1)" "unprognostic (1.67e-3)" "unprognostic (3.32e-2)" "unprognostic (4.77e-1)" "unprognostic (2.39e-1)" "unprognostic (8.48e-3)" "unprognostic (3.27e-1)" "unprognostic (3.62e-1)" "unprognostic (1.28e-1)" "unprognostic (9.23e-3)" "unprognostic (1.33e-1)" "unprognostic (8.50e-2)" GLB1L2 ENSG00000149328 "Galactosidase beta 1 like 2" Q8IW92 11 134331874-134378341 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 155.8" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 167.8" "Cancer enhanced" "Detected in many" "prostate cancer: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;NK-cell: 3.1" "Group enriched" "Detected in many" 25 "NK-cells: 3.1;T-cells: 3.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054808, HPA059955" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 29: Forebrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" 2 Nucleoplasm Vesicles "HPA054808: AB_2682608, HPA059955: AB_2684178" "unprognostic (2.63e-2)" "unprognostic (9.77e-3)" "unprognostic (2.32e-2)" "unprognostic (2.20e-2)" "unprognostic (8.07e-2)" "unprognostic (1.54e-1)" "unprognostic (5.98e-2)" "unprognostic (2.08e-2)" "unprognostic (1.51e-1)" "unprognostic (8.31e-2)" "unprognostic (1.67e-1)" "unprognostic (1.48e-1)" "unprognostic (4.73e-2)" "unprognostic (1.22e-2)" "unprognostic (2.64e-1)" "unprognostic (3.88e-3)" "unprognostic (1.01e-1)" GLCE "HSEPI, KIAA0836" ENSG00000138604 "Glucuronic acid epimerase" O94923 15 69160584-69272217 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.5" "Cell type enhanced" "Detected in all" "Excitatory neurons: 76.3;Oligodendrocytes: 144.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 1.9;monocytes: 2.3;T-cells: 2.0" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040481, HPA048216" Uncertain Approved Mitochondria "Intracellular and membrane" Enzyme NA NA 240000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 51: Oligodendrocytes - Unknown function" Mitochondria "HPA040481: AB_2677004, HPA048216: AB_2680317" "unprognostic (1.30e-1)" "unprognostic (2.39e-1)" "unprognostic (1.20e-3)" "unprognostic (7.77e-2)" "unprognostic (1.58e-1)" "unprognostic (5.55e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-1)" "unprognostic (2.56e-1)" "unprognostic (7.47e-2)" "unprognostic (1.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (6.00e-2)" "unprognostic (5.23e-1)" "unprognostic (4.07e-2)" GLDN "CLOM, COLM, colmedin, CRG-L2, UNC-122" ENSG00000186417 Gliomedin Q6ZMI3 15 51341655-51408005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.9;brain: 44.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 475.4" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050873, HPA059441" Uncertain Supported "Vesicles,Plasma membrane" "Secreted to extracellular matrix" "Developmental protein" NA NA 410000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 51: Oligodendrocytes - Unknown function" "Vesicles, Plasma membrane" "HPA050873: , HPA059441: AB_2684018" "unprognostic (5.04e-2)" "unprognostic (2.57e-2)" "unprognostic (5.15e-5)" "unprognostic (3.21e-3)" "unprognostic (2.82e-2)" "unprognostic (2.33e-1)" "unprognostic (2.07e-4)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (3.30e-2)" "unprognostic (3.15e-1)" "unprognostic (2.14e-2)" "unprognostic (9.89e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (3.80e-3)" "unprognostic (1.37e-1)" GLIPR1 "GliPR, RTVP1" ENSG00000139278 "GLI pathogenesis related 1" P48060 12 75480753-75503863 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 312.6;Extravillous trophoblasts: 473.6;Hofbauer cells: 307.5;Kupffer cells: 228.0;Langerhans cells: 487.0;Macrophages: 267.3;monocytes: 215.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA011014 Approved "Intracellular and membrane" "No annotated function" NA NA 64000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "HPA011014: AB_1849714" "unprognostic (2.32e-3)" "unprognostic (1.25e-2)" "unprognostic (1.88e-1)" "unprognostic (1.41e-2)" "unprognostic (2.19e-1)" "unprognostic (3.31e-1)" "unprognostic (2.32e-3)" "unprognostic (4.09e-1)" "unprognostic (7.58e-2)" "unprognostic (3.10e-1)" "unprognostic (7.23e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.69e-9)" "unprognostic (9.06e-3)" "unprognostic (5.08e-2)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" GLIPR1L1 MGC26856 ENSG00000173401 "GLIPR1 like 1" Q6UWM5 12 75334670-75370560 "Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 57 "testis: 31.6" "Group enriched" "Detected in some" 10 "Early spermatids: 318.6;Spermatocytes: 146.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in all" HPA042095 Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA042095: AB_10796898" "unprognostic (2.45e-3)" "unprognostic (1.56e-1)" "unprognostic (4.40e-2)" "unprognostic (1.72e-1)" "unprognostic (7.47e-2)" "unprognostic (3.04e-1)" "unprognostic (2.70e-1)" "unprognostic (4.79e-2)" "unprognostic (3.01e-1)" "unprognostic (2.89e-1)" "unprognostic (7.90e-3)" "unprognostic (1.08e-1)" "unprognostic (9.13e-3)" "unprognostic (1.02e-1)" "unprognostic (1.65e-1)" "unprognostic (2.00e-1)" "unprognostic (2.11e-2)" GLIS3 "MGC33662, ZNF515" ENSG00000107249 "GLIS family zinc finger 3" Q8NEA6 9 3824127-4348392 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Congenital hypothyroidism, Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 14.5" "Cell type enriched" "Detected in many" 7 "Astrocytes: 616.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056426 Approved Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Transcription NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Astrocytes - Unknown function" 2 Nucleoplasm "Golgi apparatus" "HPA056426: AB_2683128" "unprognostic (6.24e-2)" "unprognostic (2.30e-2)" "unprognostic (1.54e-1)" "unprognostic (3.63e-3)" "unprognostic (4.10e-1)" "unprognostic (1.88e-1)" "unprognostic (1.81e-2)" "unprognostic (7.14e-2)" "unprognostic (4.66e-2)" "unprognostic (1.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.63e-1)" "unprognostic (1.91e-3)" "unprognostic (6.88e-3)" "unprognostic (8.54e-2)" "unprognostic (1.04e-1)" "unprognostic (6.35e-2)" GLS "GAC, GAM, GLS1, KGA, KIAA0838" ENSG00000115419 Glutaminase O94925 2 190880821-190965552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 149.1" "Cell type enhanced" "Detected in all" "Collecting duct cells: 355.9;Excitatory neurons: 412.8;Proximal tubular cells: 517.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 363.0" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036223 Enhanced Supported Mitochondria "Intracellular and membrane" Enzyme No No 92000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" Mitochondria "HPA036223: AB_10669984" "unprognostic (7.45e-2)" "unprognostic (3.42e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.17e-1)" "unprognostic (2.08e-3)" "unprognostic (2.51e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (8.01e-2)" "unprognostic (9.06e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (5.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.12e-1)" GLT1D1 FLJ31978 ENSG00000151948 "Glycosyltransferase 1 domain containing 1" Q96MS3 12 128853427-128984968 "Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.7;choroid plexus: 20.6;liver: 26.9" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 15.3;dendritic cells: 29.7;Excitatory neurons: 36.3;Inhibitory neurons: 28.9;Late spermatids: 39.7;Oligodendrocyte precursor cells: 32.5" "Group enriched" "Detected in some" 6 "liver cancer: 6.2;testis cancer: 2.6;thyroid cancer: 4.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 36.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.5" "Cancer enhanced" "Detected in some" "Leukemia: 3.3" "Adipose visceral - Neutrophils, Colon - Colon enteroendocrine cells, Lung - Neutrophil_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039051, HPA039052" Enhanced Cytosol "Secreted to blood" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 74: Neutrophils - Degranulation" Cytosol "HPA039051: AB_10673299, HPA039052: AB_10672839" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (3.60e-2)" "unprognostic (3.47e-3)" "unprognostic (2.88e-1)" "unprognostic (2.53e-1)" "unprognostic (4.04e-1)" "unprognostic (1.81e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (3.93e-5)" "unprognostic (2.39e-2)" "unprognostic (2.20e-1)" "unprognostic (1.55e-3)" "unprognostic (2.41e-1)" GLT6D1 GLTDC1 ENSG00000204007 "Glycosyltransferase 6 domain containing 1" Q7Z4J2 9 135623648-135639540 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 28 "testis: 4.6" "Group enriched" "Detected in some" 54 "Early spermatids: 23.9;Late spermatids: 16.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023424 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 11: Late spermatids - Unknown function" "HPA023424: AB_1849729" GLTPD2 ENSG00000182327 "Glycolipid transfer protein domain containing 2" A6NH11 17 4788964-4790589 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 72.0" "Group enriched" "Detected in some" 11 "Hepatocytes: 153.5;Proximal enterocytes: 50.2;Proximal tubular cells: 119.4" "Cancer enriched" "Detected in many" 5 "liver cancer: 25.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 17.5" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058295, HPA065267" Uncertain Approved Vesicles "Secreted - unknown location" "No annotated function" NA NA 150000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Vesicles "HPA058295: AB_2683671, HPA065267: AB_2685451" "unprognostic (4.00e-1)" "unprognostic (1.93e-1)" "unprognostic (1.95e-3)" "unprognostic (1.70e-1)" "unprognostic (3.03e-2)" "unprognostic (1.79e-4)" "unprognostic (1.40e-1)" "unprognostic (1.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.33e-2)" "unprognostic (5.62e-4)" "unprognostic (7.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.25e-1)" "unprognostic (4.79e-1)" "unprognostic (1.71e-4)" "unprognostic (7.59e-3)" GLUD1 "GDH, GDH1, GLUD, hGDH1" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 303.2;kidney: 273.8;liver: 892.0" "Cell type enhanced" "Detected in all" "Astrocytes: 279.0;Hepatocytes: 375.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria "Intracellular and membrane" Enzyme NA NA 23000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 19: Astrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Mitochondria "HPA042492: AB_2678024, HPA044839: AB_2679107, HPA061369: AB_2684494" "unprognostic (1.48e-1)" "unprognostic (1.26e-2)" "unprognostic (3.55e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.81e-4)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" "unprognostic (5.50e-2)" "unprognostic (2.06e-1)" "unprognostic (4.57e-3)" "prognostic unfavorable (1.76e-5)" "unprognostic (1.13e-1)" "prognostic favorable (1.44e-6)" "unprognostic (2.29e-1)" "unprognostic (4.23e-2)" "unprognostic (7.19e-2)" "unprognostic (4.27e-2)" GM2A "GM2-AP, GM2AP, SAP-3" ENSG00000196743 "Ganglioside GM2 activator" P17900 5 151212150-151270440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Gangliosidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 264.8;Hofbauer cells: 93.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 30.9;dendritic cells: 39.4;monocytes: 40.2" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008063 Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" Enzyme NA NA 19000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 58: Macrophages - Innate immune response" 1 "Vesicles, Cytosol" "HPA008063: AB_1849842" "unprognostic (4.33e-2)" "unprognostic (8.97e-3)" "unprognostic (2.27e-1)" "unprognostic (3.01e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.77e-5)" "unprognostic (1.22e-1)" "unprognostic (1.72e-2)" "unprognostic (1.31e-2)" "unprognostic (1.50e-2)" "unprognostic (5.33e-3)" "unprognostic (9.81e-2)" "unprognostic (4.24e-2)" "unprognostic (4.42e-2)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" GML LY6DL ENSG00000104499 "Glycosylphosphatidylinositol anchored molecule like" Q99445 8 142834247-142916506 "Predicted intracellular proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 187.3" "Group enriched" "Detected in some" 4 "Oocytes: 22.8;Spermatocytes: 26.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" "No annotated function" NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 33: Non-specific - DNA binding" 3 Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" GNLY "D2S69E, LAG-2, LAG2, NKG5, TLA519" ENSG00000115523 Granulysin P22749 2 85685175-85698852 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 283.6;endometrium 1: 69.6;lymphoid tissue: 83.9" "Cell type enriched" "Detected in many" 6 "NK-cells: 8158.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 17662.2" "Group enriched" "Detected in all" 63 "NK-cells: 17662.2;T-cells: 7897.0" "Group enriched" "Detected in some" 7 "Leukemia: 3.8;lymphoma: 12.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung)" "Low region specificity" "Detected in many" "CAB025186, HPA058021" Enhanced "Secreted to blood" Defense NA NA 2920000 17000 "Cluster 15: NK-cells - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" 2 "CAB025186: , HPA058021: AB_2683581" "unprognostic (5.80e-2)" "unprognostic (5.64e-3)" "unprognostic (6.68e-2)" "prognostic favorable (3.48e-5)" "unprognostic (4.34e-2)" "unprognostic (9.22e-2)" "unprognostic (2.60e-1)" "unprognostic (2.79e-2)" "prognostic favorable (6.60e-5)" "unprognostic (2.61e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.46e-2)" "unprognostic (3.37e-1)" "unprognostic (1.86e-1)" "prognostic favorable (8.07e-4)" GNPTG "C16orf27, c316G12.3, CAB56184, GNPTAG" ENSG00000090581 "N-acetylglucosamine-1-phosphate transferase subunit gamma" Q9UJJ9 16 1351931-1365737 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004055 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 560000000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" 1 "Endoplasmic reticulum" Cytosol "HPA004055: AB_1079006" "unprognostic (4.37e-2)" "unprognostic (2.20e-2)" "unprognostic (1.84e-1)" "unprognostic (9.57e-3)" "unprognostic (2.70e-3)" "unprognostic (2.09e-1)" "unprognostic (3.03e-2)" "unprognostic (3.66e-1)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (6.14e-2)" "unprognostic (2.20e-1)" "unprognostic (2.31e-1)" "unprognostic (4.85e-2)" "unprognostic (2.07e-2)" GNRH1 "GNRH, GRH, LHRH" ENSG00000147437 "Gonadotropin releasing hormone 1" P01148 8 25419258-25424654 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 9.5;Peritubular cells: 9.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Group enriched" "Detected in many" 4 "basal ganglia: 19.7;hypothalamus: 12.1;olfactory bulb: 6.7" "Group enriched" "Detected in many" 13 "basal ganglia: 9.9;hypothalamus: 22.8" HPA027532 Supported "Secreted to blood" Hormone NA NA "Cluster 66: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 55: Non-specific - Transcription" "HPA027532: AB_10612111" "unprognostic (6.49e-3)" "unprognostic (7.62e-2)" "unprognostic (2.90e-1)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.53e-4)" "unprognostic (7.80e-3)" "unprognostic (2.97e-2)" "unprognostic (1.39e-1)" "unprognostic (7.99e-2)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.08e-9)" "unprognostic (7.98e-3)" "unprognostic (5.11e-2)" "unprognostic (3.49e-1)" "unprognostic (3.68e-2)" GNRH2 ENSG00000125787 "Gonadotropin releasing hormone 2" O43555 20 3043622-3045747 "Predicted secreted proteins" Hormone "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Early spermatids: 1.3;Excitatory neurons: 1.9;Inhibitory neurons: 1.9;Late spermatids: 2.1;Oligodendrocytes: 1.2;Prostatic glandular cells: 1.8;Sertoli cells: 2.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004338 Uncertain "Secreted to blood" Hormone NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 15: Non-specific - Transcription" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 36: Late spermatids - Unknown function" "HPA004338: AB_1079012" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (1.20e-2)" "unprognostic (2.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.87e-2)" "unprognostic (1.36e-2)" "unprognostic (4.04e-3)" "unprognostic (7.00e-2)" "unprognostic (1.93e-2)" "unprognostic (2.47e-4)" "unprognostic (2.69e-1)" "unprognostic (2.98e-2)" "unprognostic (1.72e-1)" "unprognostic (3.29e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" GNS ENSG00000135677 "Glucosamine (N-acetyl)-6-sulfatase" P15586 12 64713445-64759431 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 167.6;monocytes: 273.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 229.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013695, CAB026011, HPA048508" Enhanced "Intracellular and membrane" Enzyme NA NA 510000 "Cluster 40: Monocytes - Innate immune response" "Cluster 51: Thyroid gland - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 29: Monocytes - Innate immune response" "CAB026011: , HPA013695: AB_1849741, HPA048508: AB_2680423" "unprognostic (8.07e-2)" "unprognostic (2.39e-1)" "unprognostic (2.76e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.76e-4)" "unprognostic (9.33e-2)" "prognostic unfavorable (1.94e-5)" "unprognostic (1.26e-1)" "unprognostic (4.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.04e-2)" "unprognostic (3.30e-2)" "unprognostic (3.28e-3)" "unprognostic (1.42e-1)" "unprognostic (3.77e-2)" "unprognostic (1.09e-1)" "unprognostic (3.04e-1)" GOLM1 "bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73" ENSG00000135052 "Golgi membrane protein 1" Q8NBJ4 9 86026146-86100173 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 386.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 397.1;Gastric mucus-secreting cells: 240.5;Late spermatids: 447.2;Paneth cells: 244.4" "Cancer enhanced" "Detected in all" "prostate cancer: 343.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 2.2;classical monocyte: 3.5;gdT-cell: 3.5;intermediate monocyte: 2.6;neutrophil: 4.3;non-classical monocyte: 4.2;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010638, HPA011929, CAB015341" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA 81000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 45 "Golgi apparatus" "CAB015341: AB_2113334, HPA010638: AB_1849886, HPA011929: AB_1849888" "unprognostic (1.47e-1)" "unprognostic (2.31e-2)" "unprognostic (1.10e-1)" "prognostic favorable (8.14e-5)" "unprognostic (1.97e-1)" "unprognostic (4.40e-3)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.89e-3)" "unprognostic (2.81e-1)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "unprognostic (1.34e-2)" "unprognostic (5.59e-3)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.87e-3)" "unprognostic (1.23e-1)" GOT2 "KAT4, KATIV, KYAT4, mitAAT" ENSG00000125166 "Glutamic-oxaloacetic transaminase 2" P00505 16 58707131-58734342 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Aminotransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 211.8;heart muscle: 303.0;liver: 311.8;skeletal muscle: 673.7;tongue: 698.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 380.2;Hepatocytes: 167.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018139, HPA058537" Enhanced "Intracellular and membrane" Transport NA NA 2800000 "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA018139: AB_1849903, HPA058537: " "unprognostic (1.50e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-3)" "unprognostic (2.63e-3)" "unprognostic (3.02e-2)" "prognostic unfavorable (1.61e-4)" "prognostic favorable (5.75e-5)" "unprognostic (1.12e-2)" "unprognostic (3.19e-1)" "unprognostic (3.72e-2)" "unprognostic (2.27e-1)" "unprognostic (3.00e-1)" "prognostic favorable (2.90e-9)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (2.22e-1)" GP2 ZAP75 ENSG00000169347 "Glycoprotein 2" P55259 16 20309574-20327808 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 964 "pancreas: 34245.9" "Group enriched" "Detected in some" 7 "Cholangiocytes: 101.1;Exocrine glandular cells: 233.8;Prostatic glandular cells: 176.0" "Cancer enriched" "Detected in many" 14 "pancreatic cancer: 320.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.4" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "midbrain: 1.0" "HPA015739, HPA016668" Enhanced "Secreted to digestive system" Receptor NA NA 41000 "Cluster 15: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA015739: AB_1849905, HPA016668: AB_1849907" "unprognostic (2.14e-2)" "unprognostic (1.97e-2)" "unprognostic (5.68e-2)" "unprognostic (4.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.84e-1)" "unprognostic (6.35e-2)" "unprognostic (8.17e-3)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" GP6 GPVI ENSG00000088053 "Glycoprotein VI platelet" Q9HCN6 19 55013705-55038264 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;testis: 2.6" "Cell type enhanced" "Detected in some" "Early spermatids: 13.8;Excitatory neurons: 9.5;Horizontal cells: 4.4;Inhibitory neurons: 9.8;Late spermatids: 10.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA047611, HPA066482" Approved Supported "Plasma membrane" "Intracellular and membrane" "Blood coagulation" NA NA 44000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 78: Testis - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 2 "Plasma membrane" "HPA047611: , HPA066482: AB_2685674" "unprognostic (3.06e-3)" "unprognostic (4.58e-2)" "unprognostic (1.74e-5)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (7.50e-4)" "unprognostic (2.81e-1)" "unprognostic (1.00e-1)" "unprognostic (4.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.53e-1)" "unprognostic (2.62e-1)" "unprognostic (3.32e-2)" "unprognostic (5.44e-3)" "unprognostic (2.70e-2)" GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 219.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 221.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 382.6" "Colon - Enteric glia cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 9500000 "Cluster 21: Testis - Unknown function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" GPC2 "cerebroglycan, DKFZp547M109, FLJ38962" ENSG00000213420 "Glypican 2" Q8N158 7 100169606-100177381 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.0;skin 1: 5.5;testis: 11.5" "Cell type enhanced" "Detected in many" "Early spermatids: 15.0;Late spermatids: 23.1;Oligodendrocyte precursor cells: 7.5;Spermatocytes: 12.7" "Cancer enhanced" "Detected in many" "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 45.6" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025423 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 21: Testis - Unknown function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 21: Early spermatids - Spermatogenesis" "CAB025423: " "unprognostic (4.33e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-4)" "unprognostic (3.42e-2)" "unprognostic (1.27e-1)" "unprognostic (2.36e-3)" "unprognostic (6.67e-2)" "unprognostic (1.15e-1)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-4)" "unprognostic (7.25e-4)" "unprognostic (1.67e-4)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (1.05e-1)" "prognostic favorable (9.94e-4)" GPC4 K-glypican ENSG00000076716 "Glypican 4" O75487 X 133300103-133415489 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 49.2;Astrocytes: 51.7;Extravillous trophoblasts: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "testis cancer: 223.0" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030834, HPA030836" Approved Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA 190000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Alveolar cells - Lung function" 1 "Plasma membrane" Nucleoplasm "HPA030834: , HPA030836: AB_10601327" "unprognostic (9.60e-2)" "unprognostic (8.67e-2)" "unprognostic (2.29e-1)" "unprognostic (8.21e-2)" "unprognostic (8.51e-3)" "unprognostic (5.90e-3)" "unprognostic (5.68e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.54e-2)" "unprognostic (1.26e-1)" "unprognostic (5.87e-3)" "unprognostic (1.30e-1)" "prognostic favorable (1.25e-5)" "unprognostic (1.97e-1)" "unprognostic (2.89e-1)" "unprognostic (2.75e-1)" "unprognostic (2.72e-1)" GPC5 ENSG00000179399 "Glypican 5" P78333 13 91398621-92873682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.8;kidney: 7.0;testis: 5.9" "Cell type enriched" "Detected in some" 20 "Astrocytes: 3668.6" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.1" "Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040152, HPA044081" Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Astrocytes - Unknown function" 2 Nucleoplasm Cytosol "HPA040152: AB_2676863, HPA044081: AB_2678801" "unprognostic (4.99e-3)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (9.93e-5)" "prognostic unfavorable (4.37e-4)" "unprognostic (4.46e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-2)" "unprognostic (9.49e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-5)" "unprognostic (2.19e-2)" "unprognostic (1.82e-6)" "unprognostic (3.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.11e-1)" "unprognostic (6.69e-3)" GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 154.8;Excitatory neurons: 322.8;Inhibitory neurons: 475.7;Oligodendrocyte precursor cells: 649.0;Rod photoreceptor cells: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 39.0;testis cancer: 36.4" "Breast - Adipocytes (Breast), Colon - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA013601, HPA017671" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 420000 "Cluster 83: Liver - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 8: Neurons - Neuronal signaling" "Golgi apparatus, Vesicles" "HPA013601: , HPA017671: AB_1849833" "unprognostic (5.24e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" "unprognostic (9.76e-2)" "unprognostic (1.72e-1)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-2)" "unprognostic (3.71e-2)" "unprognostic (2.53e-3)" "unprognostic (6.21e-3)" "unprognostic (7.42e-2)" "unprognostic (3.36e-1)" "unprognostic (3.35e-3)" GPD2 ENSG00000115159 "Glycerol-3-phosphate dehydrogenase 2" P43304 2 156435290-156613735 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 143.4;Late spermatids: 101.0;Oligodendrocyte precursor cells: 139.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.3;eosinophil: 1.7;intermediate monocyte: 1.6;myeloid DC: 2.7;neutrophil: 1.1;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 1.7;monocytes: 3.3" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008012, HPA045506" Enhanced Supported Mitochondria "Intracellular and membrane" Enzyme NA NA 620000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 79: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 76: Oligodendrocyte precursor - Unknown function" Mitochondria "HPA008012: AB_1079013, HPA045506: AB_2679355" "unprognostic (1.30e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (4.79e-3)" "unprognostic (3.25e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (2.60e-3)" "unprognostic (6.67e-2)" "unprognostic (6.02e-3)" "unprognostic (1.73e-1)" "unprognostic (1.89e-1)" "unprognostic (2.41e-1)" "unprognostic (1.01e-2)" GPHA2 "A2, GPA2, MGC126572, ZSIG51" ENSG00000149735 "Glycoprotein hormone subunit alpha 2" Q96T91 11 64934471-64935893 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "pancreas: 348.9" "Group enriched" "Detected in some" 4 "Exocrine glandular cells: 10.0;Oocytes: 14.7;Spermatocytes: 8.0" "Cancer enriched" "Detected in some" 7 "testis cancer: 15.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 1.5;liver cancer: 1.3;Rhabdoid: 1.1" "Kidney - Proximal tubular cells, Pancreas - Exocrine glandular cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA067068 Approved Vesicles "Secreted to blood" Hormone NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 1 Vesicles "HPA067068: " "unprognostic (1.13e-1)" "unprognostic (8.31e-3)" "unprognostic (1.51e-2)" "unprognostic (9.22e-4)" "unprognostic (7.88e-3)" "unprognostic (2.62e-1)" "unprognostic (1.45e-1)" "unprognostic (3.20e-2)" "unprognostic (1.82e-1)" "unprognostic (1.75e-1)" "unprognostic (5.03e-2)" "unprognostic (9.86e-3)" "unprognostic (1.70e-1)" GPHB5 "GPB5, ZLUT1" ENSG00000179600 "Glycoprotein hormone subunit beta 5" Q86YW7 14 63312835-63318935 "Predicted secreted proteins" Hormone "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Hormone NA NA "Cluster 57: Stomach & Colon cancer - Digestion" 7 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 1146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171, CAB080077, CAB080078, CAB080085" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to blood" Cytokine NA No 86000000 "Cluster 25: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" Cytosol "Plasma membrane" "CAB018655: AB_2112653, CAB040563: , CAB080077: , CAB080078: , CAB080085: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" GPIHBP1 "GPI-HBP1, LOC338328" ENSG00000277494 "Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1" Q8IV16 8 143213218-143217170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.6;brain: 70.8" "Cell type enriched" "Detected in some" 4 "Adipocytes: 328.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066302 Enhanced "Intracellular and membrane" Transport NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "HPA066302: AB_2685654" "unprognostic (2.05e-1)" "unprognostic (3.11e-2)" "unprognostic (1.71e-3)" "unprognostic (2.43e-3)" "unprognostic (1.58e-1)" "unprognostic (9.50e-2)" "unprognostic (1.75e-3)" "unprognostic (8.01e-2)" "unprognostic (2.04e-1)" "unprognostic (1.30e-1)" "unprognostic (9.31e-2)" "unprognostic (8.69e-2)" "unprognostic (5.06e-3)" "unprognostic (9.65e-3)" "unprognostic (1.41e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-3)" GPLD1 ENSG00000112293 "Glycosylphosphatidylinositol specific phospholipase D1" P80108 6 24424565-24495205 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 44.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 49.3;Excitatory neurons: 60.4;Hepatocytes: 80.5;Inhibitory neurons: 75.0;Oligodendrocyte precursor cells: 31.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 6.3" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008625, HPA012500" Uncertain "Secreted to blood" Enzyme NA NA 103000000000 3100000000 "Cluster 83: Liver - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 43: Hepatocytes - Metabolism" "CAB008625: AB_1621070, HPA012500: AB_1849931" "unprognostic (6.80e-3)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (4.81e-5)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.12e-4)" "unprognostic (6.37e-4)" "unprognostic (7.93e-2)" "unprognostic (2.86e-2)" "unprognostic (6.07e-4)" "unprognostic (2.68e-1)" "unprognostic (5.28e-4)" "unprognostic (2.20e-1)" "unprognostic (9.98e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" GPNMB "HGFIN, NMB" ENSG00000136235 "Glycoprotein nmb" Q14956 7 23235967-23275108 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 565.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 243.7;Cardiomyocytes: 250.8;Fibroblasts: 256.8;Hofbauer cells: 706.1;Macrophages: 223.7;Melanocytes: 934.5;Suprabasal keratinocytes: 213.8" "Cancer enhanced" "Detected in all" "melanoma: 354.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.1;intermediate monocyte: 3.9" "Lineage enriched" "Detected in single" 6 "monocytes: 3.9" "Cancer enriched" "Detected in many" 6 "skin cancer: 692.4" "Breast - Fibroblasts, Colon - Fibroblasts, Lung - Macrophages, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Region enhanced" "Detected in many" "olfactory bulb: 9.7" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA NA 33000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 21: Testis - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 1 "unprognostic (3.37e-2)" "unprognostic (1.18e-1)" "unprognostic (6.65e-2)" "unprognostic (1.82e-1)" "unprognostic (5.14e-2)" "unprognostic (4.16e-1)" "unprognostic (1.39e-1)" "unprognostic (3.89e-2)" "unprognostic (7.13e-2)" "unprognostic (2.79e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (2.08e-3)" "unprognostic (1.24e-2)" "unprognostic (3.46e-2)" "unprognostic (4.82e-1)" "unprognostic (6.95e-2)" GPR15LG "AP-57, C10orf99, CSBF, FLJ21763, GPR15L, RLLV1833, UNQ1833" ENSG00000188373 "G protein-coupled receptor 15 ligand" Q6UWK7 10 84173801-84185294 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 187.8;intestine: 265.9;vagina: 111.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 1331.7;Enteroendocrine cells: 271.4;Intestinal goblet cells: 217.5;Paneth cells: 776.7;Proximal enterocytes: 345.9;Suprabasal keratinocytes: 408.3;Undifferentiated cells: 211.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 91.5;head and neck cancer: 102.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 26.7;head and neck cancer: 7.5" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050920 Enhanced "Secreted in other tissues" Cytokine NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "HPA050920: AB_2681274" "unprognostic (3.13e-2)" "unprognostic (1.43e-1)" "unprognostic (6.04e-2)" "unprognostic (1.78e-2)" "unprognostic (7.46e-3)" "unprognostic (2.05e-1)" "unprognostic (7.98e-2)" "unprognostic (2.04e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (3.70e-1)" "unprognostic (4.67e-2)" GPR162 "A-2, GRCA" ENSG00000250510 "G protein-coupled receptor 162" Q16538 12 6821624-6829972 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 147.1;choroid plexus: 75.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 70.3;Ciliated cells: 50.4;Excitatory neurons: 35.5;Horizontal cells: 71.8;Inhibitory neurons: 31.5;Muller glia cells: 46.1" "Cancer enriched" "Detected in many" 6 "glioma: 16.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 17.5" "Group enriched" "Detected in many" 6 "granulocytes: 17.5;monocytes: 6.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.0" "Heart muscle - Fibroblasts, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055135 Enhanced Approved "Centriolar satellite" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" 2 "Centriolar satellite" "HPA055135: AB_2682710" "unprognostic (4.76e-2)" "unprognostic (8.00e-2)" "unprognostic (8.24e-3)" "unprognostic (1.31e-2)" "unprognostic (1.31e-1)" "unprognostic (2.38e-1)" "unprognostic (4.78e-2)" "unprognostic (2.25e-2)" "unprognostic (5.83e-3)" "unprognostic (1.18e-1)" "prognostic favorable (4.29e-5)" "unprognostic (3.82e-3)" "prognostic unfavorable (1.37e-6)" "unprognostic (3.10e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.64e-2)" GPX3 ENSG00000211445 "Glutathione peroxidase 3" P22352 5 151020591-151028988 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 10840.5" "Group enriched" "Detected in many" 5 "Muller glia cells: 4288.3;Proximal tubular cells: 16878.3" "Cancer enhanced" "Detected in all" "renal cancer: 605.6;thyroid cancer: 856.0" "Group enriched" "Detected in all" 4 "choroid plexus: 1127.5;medulla oblongata: 588.7" "Immune cell enriched" "Detected in some" 5 "neutrophil: 20.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.8" "Cancer enhanced" "Detected in all" "ovarian cancer: 198.7;thyroid cancer: 178.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Region enhanced" "Detected in all" "hypothalamus: 239.6" "Low region specificity" "Detected in all" CAB069456 Approved "Secreted to blood" Enzyme NA NA 5090000000 6200000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 38: Proximal tubular cells - Transmembrane transport" "CAB069456: AB_1616682" "unprognostic (4.03e-1)" "unprognostic (7.35e-2)" "unprognostic (5.05e-3)" "unprognostic (9.01e-2)" "unprognostic (1.41e-2)" "unprognostic (8.13e-2)" "unprognostic (1.39e-2)" "unprognostic (1.62e-1)" "unprognostic (5.75e-3)" "unprognostic (2.70e-3)" "unprognostic (8.17e-3)" "unprognostic (1.14e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (2.14e-1)" "unprognostic (5.11e-2)" "unprognostic (1.26e-1)" GPX4 "MCSP, PHGPx" ENSG00000167468 "Glutathione peroxidase 4" P36969 19 1103982-1106791 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Developmental protein, Oxidoreductase, Peroxidase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Late spermatids: 18077.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008630, HPA047224, HPA058546" Enhanced Approved Nucleoplasm,Mitochondria "Intracellular and membrane" "Developmental protein" NA NA 150000 "Cluster 29: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" "CAB008630: AB_1616685, HPA047224: AB_2679990, HPA058546: AB_2683749" "unprognostic (8.42e-3)" "prognostic favorable (7.18e-4)" "unprognostic (8.14e-3)" "prognostic favorable (1.84e-5)" "unprognostic (1.00e-1)" "unprognostic (8.72e-2)" "unprognostic (2.53e-3)" "unprognostic (8.49e-2)" "unprognostic (2.69e-2)" "unprognostic (1.47e-1)" "prognostic favorable (7.72e-4)" "unprognostic (1.29e-1)" "prognostic favorable (8.61e-4)" "unprognostic (1.61e-2)" "unprognostic (2.20e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" GPX5 ENSG00000224586 "Glutathione peroxidase 5" O75715 6 28525881-28534955 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 9.0" "Group enriched" "Detected in some" 43 "Early spermatids: 15.3;Late spermatids: 42.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted in male reproductive system" Enzyme NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 36: Late spermatids - Unknown function" "unprognostic (3.34e-2)" "unprognostic (3.74e-2)" GPX6 GPXP3 ENSG00000198704 "Glutathione peroxidase 6" P59796 6 28503296-28528215 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "epididymis: 3.2" "Group enriched" "Detected in some" 4 "Early spermatids: 2.9;Late spermatids: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 16 "basal ganglia: 23.9" "Low region specificity" "Detected in many" "Secreted in male reproductive system" Enzyme NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 34: Testis cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" "unprognostic (2.99e-2)" GPX7 "FLJ14777, GPX6, NPGPx" ENSG00000116157 "Glutathione peroxidase 7" Q96SL4 1 52602371-52609051 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 46.1;Plasma cells: 32.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to blood" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 18: Non-specific - Ribosome" "Cluster 36: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 50: Connective tissue cells - ECM organization" 10 "unprognostic (5.87e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (7.43e-3)" "unprognostic (3.18e-1)" "unprognostic (5.64e-2)" "unprognostic (6.12e-3)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (8.18e-2)" "unprognostic (4.17e-1)" "unprognostic (2.48e-3)" "prognostic unfavorable (2.26e-5)" "unprognostic (1.14e-2)" "unprognostic (9.24e-2)" "unprognostic (3.08e-2)" "unprognostic (5.44e-2)" GREM1 "CKTSF1B1, CRAC1, DAND2, DRM, gremlin, HMPS" ENSG00000166923 "Gremlin 1, DAN family BMP antagonist" O60565 15 32718004-32745106 "Disease related genes, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 109.1;smooth muscle: 65.6" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 362.1" "Cancer enhanced" "Detected in many" "stomach cancer: 24.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 31.2;thyroid cancer: 33.0" "Testis - Spermatogonia" "Group enriched" "Detected in many" 5 "hippocampal formation: 3.2;olfactory bulb: 10.9" "Low region specificity" "Detected in many" HPA007526 Uncertain "Secreted to blood" Cytokine NA NA 242000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 4 "HPA007526: AB_1849971" "unprognostic (4.74e-2)" "unprognostic (2.78e-1)" "unprognostic (4.63e-2)" "unprognostic (6.80e-2)" "unprognostic (3.58e-1)" "unprognostic (1.72e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.46e-4)" "unprognostic (5.33e-2)" "unprognostic (2.32e-1)" "unprognostic (7.20e-3)" "unprognostic (2.79e-1)" "unprognostic (2.13e-11)" "unprognostic (1.77e-2)" "unprognostic (6.60e-2)" "unprognostic (3.29e-2)" "unprognostic (1.16e-3)" GREM2 "CKTSF1B2, DAND3, FLJ21195, Prdc" ENSG00000180875 "Gremlin 2, DAN family BMP antagonist" Q9H772 1 240489573-240612155 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Heparin-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 30.3;liver: 25.7" "Cell type enriched" "Detected in many" 10 "Syncytiotrophoblasts: 312.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.6" "Kidney - Fibroblasts, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB009920 Approved "Secreted to blood" Cytokine NA NA 12000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "CAB009920: AB_2279266" "unprognostic (2.01e-1)" "unprognostic (2.49e-1)" "unprognostic (7.41e-2)" "unprognostic (7.58e-3)" "unprognostic (2.82e-3)" "unprognostic (1.34e-1)" "unprognostic (8.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.31e-2)" "unprognostic (6.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.97e-2)" "unprognostic (3.07e-8)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.38e-2)" GRHL3 "SOM, TFCP2L4" ENSG00000158055 "Grainyhead like transcription factor 3" Q8TE85 1 24199558-24364482 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 117.4;skin 1: 51.8;vagina: 46.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 27.5;Basal squamous epithelial cells: 30.1;Squamous epithelial cells: 125.2;Suprabasal keratinocytes: 108.5" "Group enriched" "Detected in many" 4 "cervical cancer: 13.3;head and neck cancer: 16.1;urothelial cancer: 28.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 37.7;testis cancer: 30.1" "Adipose visceral - Mesothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA059960 Enhanced Approved Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 2 Nucleoplasm "HPA059960: AB_2684180" "unprognostic (8.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.95e-2)" "unprognostic (7.83e-3)" "unprognostic (7.58e-3)" "unprognostic (6.28e-3)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (9.01e-3)" "unprognostic (4.03e-2)" "unprognostic (1.24e-1)" "unprognostic (7.36e-2)" "unprognostic (8.59e-4)" "unprognostic (9.79e-2)" "unprognostic (1.83e-1)" "unprognostic (6.97e-3)" "unprognostic (7.42e-2)" GRIA3 "GluA3, GLUR3, GLURC, MRX94" ENSG00000125675 "Glutamate ionotropic receptor AMPA type subunit 3" P42263 X 123184153-123490915 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.6;retina: 16.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 452.9;Inhibitory neurons: 380.2;Oligodendrocyte precursor cells: 361.3" "Cancer enriched" "Detected in some" 11 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Brain cancer: 2.9;liver cancer: 4.0;Neuroblastoma: 3.0;thyroid cancer: 3.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Fibroblast_2, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058659, HPA073344" Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "HPA058659: AB_2683791, HPA073344: " "unprognostic (2.14e-2)" "unprognostic (6.00e-2)" "unprognostic (2.02e-2)" "unprognostic (2.94e-3)" "unprognostic (5.09e-2)" "unprognostic (4.29e-4)" "unprognostic (2.42e-1)" "unprognostic (6.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (3.78e-3)" "unprognostic (8.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" GRIA4 "GluA4, GLUR4, GLURD" ENSG00000152578 "Glutamate ionotropic receptor AMPA type subunit 4" P48058 11 105609535-105982090 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 62.4;retina: 30.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 772.7;Horizontal cells: 237.3;Inhibitory neurons: 1002.4;Oligodendrocyte precursor cells: 708.9" "Cancer enriched" "Detected in some" 5 "glioma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 9.9;Rhabdoid: 9.5" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063282 Uncertain "Focal adhesion sites" "Intracellular and membrane" Receptor NA NA "Cluster 28: Neuronal - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "Focal adhesion sites" "HPA063282: " "unprognostic (1.45e-1)" "unprognostic (2.63e-1)" "unprognostic (4.09e-4)" "unprognostic (4.45e-3)" "unprognostic (1.92e-3)" "unprognostic (4.14e-4)" "unprognostic (1.40e-2)" "unprognostic (3.73e-4)" "unprognostic (1.62e-1)" "unprognostic (3.89e-1)" "unprognostic (2.04e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (2.48e-1)" "unprognostic (1.38e-1)" "unprognostic (3.35e-2)" "unprognostic (1.28e-1)" GRIK2 "GluK2, GLUR6, MRT6" ENSG00000164418 "Glutamate ionotropic receptor kainate type subunit 2" Q13002 6 100962701-102081622 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "brain: 61.2" "Group enriched" "Detected in some" 26 "Excitatory neurons: 699.9;Inhibitory neurons: 2270.7;Oligodendrocyte precursor cells: 1157.9" "Cancer enriched" "Detected in some" 5 "glioma: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.2;skin cancer: 8.4" "Colon - Enteric glia cells, Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014395, HPA014623, CAB022463" Approved "Intracellular and membrane" Receptor NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "CAB022463: , HPA014395: AB_1850303, HPA014623: AB_1850305" "unprognostic (1.43e-3)" "unprognostic (1.26e-2)" "unprognostic (3.99e-2)" "unprognostic (3.20e-1)" "unprognostic (1.92e-1)" "unprognostic (3.48e-2)" "unprognostic (2.57e-1)" "unprognostic (4.32e-2)" "unprognostic (8.46e-2)" "unprognostic (9.19e-2)" "unprognostic (4.01e-2)" "unprognostic (1.36e-1)" "unprognostic (1.34e-5)" "unprognostic (1.94e-3)" "unprognostic (7.78e-2)" "unprognostic (1.09e-2)" "unprognostic (8.68e-4)" GRM3 "GPRC1C, mGlu3, MGLUR3" ENSG00000198822 "Glutamate metabotropic receptor 3" Q14832 7 86643909-86864879 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "brain: 50.4" "Group enriched" "Detected in some" 19 "Astrocytes: 389.5;Excitatory neurons: 262.7;Oligodendrocytes: 957.1" "Cancer enriched" "Detected in single" 7 "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 51: Oligodendrocytes - Unknown function" "unprognostic (2.05e-1)" "unprognostic (3.78e-2)" "unprognostic (1.90e-1)" "unprognostic (2.70e-3)" "unprognostic (3.16e-1)" "unprognostic (1.07e-3)" "unprognostic (6.99e-3)" "unprognostic (2.98e-1)" "unprognostic (2.71e-1)" "unprognostic (9.13e-3)" "unprognostic (1.88e-3)" "unprognostic (2.04e-1)" "unprognostic (3.91e-3)" "unprognostic (4.00e-2)" "unprognostic (9.34e-2)" "unprognostic (1.72e-3)" "unprognostic (1.12e-2)" GRM5 "GPRC1E, mGlu5, MGLUR5, PPP1R86" ENSG00000168959 "Glutamate metabotropic receptor 5" P41594 11 88504576-89065982 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 14.4" "Group enriched" "Detected in some" 26 "Excitatory neurons: 872.0;Inhibitory neurons: 927.5;Oligodendrocyte precursor cells: 976.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Gallbladder cancer: 2.6" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 65: Neurons - Synaptic function" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (9.57e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (2.62e-1)" "unprognostic (1.26e-1)" "unprognostic (7.16e-2)" "unprognostic (8.15e-4)" "unprognostic (3.43e-2)" GRN "CLN11, PCDGF, PGRN" ENSG00000030582 "Granulin precursor" P28799 17 44345246-44353106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1429.9;Kupffer cells: 774.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 2059.0;intermediate monocyte: 1123.1;myeloid DC: 1535.9;neutrophil: 854.4;non-classical monocyte: 550.5;plasmacytoid DC: 1334.2" "Group enriched" "Detected in all" 8 "dendritic cells: 1535.9;granulocytes: 854.4;monocytes: 2059.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008763, CAB019394, HPA028747" Uncertain Enhanced Endosomes,Lysosomes "Secreted to blood" Cytokine NA NA 138000000 110000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" 216 Lysosomes Endosomes "CAB019394: , HPA008763: AB_1850339, HPA028747: AB_10603767" "unprognostic (1.84e-1)" "unprognostic (2.34e-1)" "unprognostic (8.38e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (7.41e-2)" "unprognostic (3.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-2)" "unprognostic (1.52e-1)" "unprognostic (6.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" GRP ENSG00000134443 "Gastrin releasing peptide" P07492 18 59220158-59230774 "Predicted intracellular proteins, Predicted secreted proteins" "Mast cell degranulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7;lung: 8.7;stomach 1: 11.9" "Group enriched" "Detected in some" 4 "Breast myoepithelial cells: 32.1;Early spermatids: 19.5;Late spermatids: 12.1;Smooth muscle cells: 9.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.6" "Region enriched" "Detected in many" 5 "midbrain: 56.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 26 "Bone cancer: 180.1;lung cancer: 47.9;thyroid cancer: 71.6" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Parafollicular cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 33.2" "Secreted in other tissues" Other NA NA 340000 "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "unprognostic (3.91e-2)" "unprognostic (1.85e-1)" "unprognostic (2.30e-3)" "unprognostic (3.21e-2)" "unprognostic (7.86e-3)" "unprognostic (3.01e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (1.79e-1)" "unprognostic (5.86e-4)" "unprognostic (2.65e-4)" "unprognostic (9.94e-2)" "unprognostic (6.99e-2)" "unprognostic (5.16e-2)" GSDMD "DF5L, FLJ12150, GSDMDC1" ENSG00000104518 "Gasdermin D" P57764 8 143553207-143563062 "Predicted intracellular proteins, Transporters" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 181.0;Proximal enterocytes: 283.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004656, HPA044487" Uncertain Supported Nucleoplasm "Intracellular and membrane" Immunity NA NA 11000 "Cluster 33: Non-specific - ATP binding" "Cluster 47: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 7 Nucleoplasm "CAB004656: AB_426076, HPA044487: AB_2678957" "unprognostic (1.11e-2)" "unprognostic (8.44e-2)" "unprognostic (6.72e-2)" "unprognostic (4.00e-2)" "unprognostic (4.38e-2)" "unprognostic (1.10e-1)" "unprognostic (1.66e-1)" "unprognostic (2.65e-1)" "unprognostic (7.20e-2)" "unprognostic (6.36e-2)" "unprognostic (4.66e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (1.43e-4)" "unprognostic (8.51e-3)" "unprognostic (1.60e-1)" "unprognostic (1.96e-1)" "unprognostic (6.77e-3)" GSG1 MGC3146 ENSG00000111305 "Germ cell associated 1" Q2KHT4 12 13083532-13103683 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 418.0" "Cell type enriched" "Detected in some" 7 "Late spermatids: 10952.0" "Cancer enhanced" "Detected in single" "testis cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "Rhabdoid: 117.1" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Late spermatids - Unknown function" 1 "unprognostic (1.50e-1)" "unprognostic (2.21e-2)" "unprognostic (6.33e-2)" "unprognostic (2.36e-2)" "unprognostic (1.34e-1)" "unprognostic (8.01e-2)" "unprognostic (1.04e-1)" "unprognostic (4.52e-1)" "unprognostic (6.85e-2)" "unprognostic (8.23e-2)" "unprognostic (5.91e-2)" "unprognostic (3.20e-3)" "unprognostic (1.48e-1)" "unprognostic (3.65e-2)" "unprognostic (1.79e-1)" "unprognostic (6.32e-3)" GSN DKFZp313L0718 ENSG00000148180 Gelsolin P06396 9 121207794-121332843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cilium biogenesis/degradation" "Actin capping, Actin-binding" "Amyloidosis, Cancer-related genes, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 2404.8" "Cell type enhanced" "Detected in all" "Adipocytes: 1460.5;Fibroblasts: 3746.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 1140.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Colon - Fibroblasts, Lung - Fibroblast_2, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Region enriched" "Detected in all" 4 "white matter: 869.4" "Low region specificity" "Detected in all" "CAB010823, CAB016728, CAB036009, HPA054026" Supported Supported "Actin filaments" "Secreted to blood" Other NA NA 112000000000 240000000000 "Cluster 29: Non-specific - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 126 "Actin filaments" "CAB010823: , CAB016728: , CAB036009: , HPA054026: AB_2682347" "unprognostic (3.25e-2)" "unprognostic (4.44e-3)" "unprognostic (1.22e-1)" "unprognostic (3.10e-3)" "unprognostic (4.23e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (6.54e-2)" "unprognostic (6.56e-2)" "unprognostic (3.06e-2)" "unprognostic (8.01e-3)" "unprognostic (4.98e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.79e-5)" GUCA2A "GUCA2, STARA" ENSG00000197273 "Guanylate cyclase activator 2A" Q02747 1 42162690-42164745 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "intestine: 901.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4872.7;Paneth cells: 22598.0;Proximal enterocytes: 11340.5" "Group enriched" "Detected in many" 7 "colorectal cancer: 31.6;urothelial cancer: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 11.2" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA018215 Enhanced "Secreted to blood" "No annotated function" NA NA 18000000 "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 9 "HPA018215: AB_1850443" "unprognostic (7.98e-3)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (9.07e-2)" "unprognostic (1.14e-1)" "unprognostic (8.06e-2)" "unprognostic (2.89e-1)" "unprognostic (3.10e-1)" "unprognostic (9.15e-2)" GUCA2B ENSG00000044012 "Guanylate cyclase activator 2B" Q16661 1 42153410-42155820 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 139.3" "Cell type enriched" "Detected in some" 12 "Paneth cells: 24388.4" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "colorectal cancer: 16.5" "Colon - Colon enterocytes, Skin - Keratinocyte (granular), Stomach - Parietal cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Secreted to blood" "No annotated function" NA NA 77700 1200000 "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 40: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" 2 "unprognostic (2.59e-2)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (6.22e-2)" "unprognostic (1.86e-1)" GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" Enzyme NA NA 330000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 58: Macrophages - Innate immune response" Vesicles "HPA036322: AB_10670796, HPA036323: AB_2675059" "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" GXYLT1 "FLJ43151, GLT8D3" ENSG00000151233 "Glucoside xylosyltransferase 1" Q4G148 12 42081845-42144874 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077997 Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme NA NA 3200000 "Cluster 25: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Endoplasmic reticulum" Vesicles "HPA077997: " "unprognostic (1.09e-2)" "unprognostic (1.16e-1)" "unprognostic (1.53e-1)" "unprognostic (5.07e-1)" "unprognostic (1.22e-1)" "unprognostic (9.89e-2)" "unprognostic (5.22e-3)" "unprognostic (1.77e-2)" "unprognostic (4.42e-3)" "unprognostic (1.46e-2)" "unprognostic (1.64e-2)" "unprognostic (3.20e-1)" "unprognostic (1.92e-2)" "unprognostic (8.16e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-2)" "prognostic favorable (3.91e-4)" GYPB "CD235b, GPB, MNS, SS" ENSG00000250361 "Glycophorin B (MNS blood group)" P06028 4 143996104-144019380 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "bone marrow: 62.2" "Cell type enriched" "Detected in some" 310 "Erythroid cells: 915.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 149 "Leukemia: 17.3" "Liver - Erythroid cells" "Intracellular and membrane" Other NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 4 GZMA "CTLA3, HFSP" ENSG00000145649 "Granzyme A" P12544 5 55102646-55110252 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 66.4" "Group enriched" "Detected in many" 32 "NK-cells: 1198.7;T-cells: 673.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 15 "gdT-cell: 943.6;MAIT T-cell: 927.9;memory CD4 T-cell: 250.8;memory CD8 T-cell: 922.8;naive CD8 T-cell: 495.6;NK-cell: 720.7" "Group enriched" "Detected in all" 42 "NK-cells: 720.7;T-cells: 943.6" "Cancer enriched" "Detected in some" 5 "lymphoma: 68.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA054134, HPA076751" Enhanced "Secreted to blood" Enzyme NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" "HPA054134: AB_2682395, HPA076751: " "prognostic favorable (7.27e-4)" "unprognostic (7.29e-3)" "unprognostic (1.50e-2)" "prognostic favorable (6.44e-6)" "unprognostic (2.96e-3)" "unprognostic (1.85e-3)" "unprognostic (8.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.15e-3)" "unprognostic (3.03e-2)" "unprognostic (1.77e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (1.26e-6)" "unprognostic (5.91e-2)" "unprognostic (5.57e-1)" "unprognostic (5.73e-3)" "unprognostic (3.33e-3)" GZMB "CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT" ENSG00000100453 "Granzyme B" P10144 14 24630954-24634267 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 65.8;lymphoid tissue: 35.3" "Group enriched" "Detected in many" 7 "dendritic cells: 2843.3;NK-cells: 1916.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "hypothalamus: 14.2" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 6750.5" "Lineage enriched" "Detected in all" 5 "dendritic cells: 6750.5" "Cancer enriched" "Detected in some" 59 "lymphoma: 294.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "CAB000376, HPA003418" Enhanced "Secreted to blood" Enzyme NA NA 2170 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" 1 "CAB000376: AB_323716, HPA003418: AB_1079020" "prognostic favorable (7.27e-4)" "unprognostic (2.82e-3)" "unprognostic (8.54e-2)" "prognostic favorable (1.58e-5)" "unprognostic (2.07e-3)" "unprognostic (1.48e-3)" "unprognostic (4.43e-2)" "unprognostic (8.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.05e-3)" "unprognostic (4.26e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.10e-7)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" GZMH "CCP-X, CGL-2, CSP-C, CTLA1, CTSGL2" ENSG00000100450 "Granzyme H" P20718 14 24606480-24609699 "Enzymes, Predicted secreted proteins" Cytolysis "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.4;lymphoid tissue: 24.6" "Group enriched" "Detected in some" 19 "NK-cells: 559.1;T-cells: 241.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 5 "gdT-cell: 1682.7;memory CD4 T-cell: 492.5;memory CD8 T-cell: 1389.7;naive CD8 T-cell: 1217.5" "Lineage enriched" "Detected in all" 7 "T-cells: 1682.7" "Cancer enriched" "Detected in single" 5 "lymphoma: 1.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA029200 Enhanced "Secreted to blood" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" "HPA029200: AB_10602908" "unprognostic (3.72e-3)" "unprognostic (1.47e-3)" "unprognostic (5.35e-2)" "prognostic favorable (2.00e-6)" "unprognostic (8.80e-2)" "unprognostic (1.65e-3)" "unprognostic (2.08e-3)" "unprognostic (1.13e-1)" "unprognostic (1.62e-2)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (1.74e-6)" "unprognostic (1.23e-1)" "unprognostic (1.80e-1)" "unprognostic (3.35e-2)" "unprognostic (2.77e-3)" GZMK "PRSS, TRYP2" ENSG00000113088 "Granzyme K" P49863 5 55024256-55034570 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 97.2" "Group enriched" "Detected in many" 7 "NK-cells: 132.7;T-cells: 263.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 742.7;NK-cell: 506.4" "Group enriched" "Detected in many" 199 "NK-cells: 506.4;T-cells: 742.7" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA059953, HPA063181, HPA065895" Enhanced Approved "Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Golgi apparatus" "HPA059953: , HPA063181: AB_2684955, HPA065895: " "prognostic favorable (8.68e-4)" "unprognostic (3.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.83e-3)" "unprognostic (2.61e-2)" "unprognostic (1.12e-3)" "unprognostic (1.03e-3)" "unprognostic (8.13e-3)" "unprognostic (3.50e-2)" "unprognostic (4.53e-2)" "unprognostic (9.74e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.3;lymphoid tissue: 22.2" "Group enriched" "Detected in many" 34 "NK-cells: 666.9;T-cells: 222.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 585.3" "Group enriched" "Detected in all" 33 "NK-cells: 195.3;T-cells: 585.3" "Cancer enhanced" "Detected in some" "Leukemia: 5.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" Immunity NA NA "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 1 "HPA015624: AB_2669245" "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favorable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favorable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" H6PD "GDH, H6PDH" ENSG00000049239 "Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase" O95479 1 9234774-9271337 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 92.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 140.1;Mesothelial cells: 89.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004824, HPA005440" Approved Uncertain Cytosol "Intracellular and membrane" Enzyme NA NA 140000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 75: Serous glandular cells - Salivary secretion" Cytosol "HPA004824: AB_1079037, HPA005440: AB_1079036" "unprognostic (4.83e-3)" "unprognostic (3.91e-2)" "unprognostic (1.18e-1)" "unprognostic (3.49e-1)" "unprognostic (5.53e-3)" "unprognostic (2.86e-2)" "unprognostic (8.35e-2)" "unprognostic (5.18e-2)" "unprognostic (9.73e-2)" "unprognostic (1.26e-3)" "unprognostic (2.16e-2)" "unprognostic (7.35e-3)" "unprognostic (8.20e-2)" "unprognostic (3.61e-1)" "unprognostic (1.30e-1)" "unprognostic (8.65e-2)" "unprognostic (1.95e-1)" HABP2 "FSAP, HABP, HGFAL, PHBP" ENSG00000148702 "Hyaluronan binding protein 2" Q14520 10 113550837-113589602 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "liver: 424.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 120.2;Ductal cells: 38.7;Hepatocytes: 185.7;Kupffer cells: 33.7;Oocytes: 85.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 92.4" "Region enhanced" "Detected in some" "cerebral cortex: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 14.7;liver cancer: 19.4" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA019518 Uncertain "Secreted to blood" Enzyme NA NA 20200000000 4400000000 "Cluster 31: Liver - Plasma proteins" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "HPA019518: AB_1850467" "unprognostic (3.89e-2)" "unprognostic (6.15e-2)" "unprognostic (1.33e-1)" "unprognostic (1.24e-1)" "unprognostic (1.45e-1)" "unprognostic (6.92e-2)" "unprognostic (1.01e-1)" "unprognostic (5.86e-3)" "unprognostic (1.67e-1)" "unprognostic (9.78e-2)" "unprognostic (5.10e-2)" "unprognostic (4.77e-2)" "unprognostic (9.18e-3)" "unprognostic (2.62e-3)" "unprognostic (2.11e-1)" "unprognostic (3.22e-1)" "unprognostic (9.05e-3)" HAMP "HEPC, HFE2B, LEAP-1, LEAP1" ENSG00000105697 "Hepcidin antimicrobial peptide" P81172 19 35280716-35285143 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide, Hormone" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 2003.9" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 2832.2" "Group enriched" "Detected in many" 12 "glioma: 6.5;liver cancer: 16.3" "Region enhanced" "Detected in all" "medulla oblongata: 70.6" "Group enriched" "Detected in some" 7 "myeloid DC: 1.5;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.7" "Cancer enriched" "Detected in some" 5 "liver cancer: 52.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Hormone NA NA 1900000 10000000 "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "unprognostic (5.53e-2)" "unprognostic (5.02e-4)" "unprognostic (2.10e-3)" "unprognostic (4.69e-3)" "unprognostic (5.35e-2)" "unprognostic (2.24e-1)" "unprognostic (3.92e-2)" "unprognostic (9.36e-2)" "unprognostic (2.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.61e-1)" "unprognostic (1.86e-1)" "unprognostic (3.68e-7)" "unprognostic (4.11e-2)" "unprognostic (3.93e-2)" "unprognostic (4.08e-2)" "unprognostic (7.77e-2)" HAPLN1 CRTL1 ENSG00000145681 "Hyaluronan and proteoglycan link protein 1" P10915 5 83637805-83720855 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 72.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 16.3;Inhibitory neurons: 34.1;Smooth muscle cells: 74.0;Syncytiotrophoblasts: 11.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 45.0;testis cancer: 64.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019105, HPA019482, HPA025238" Enhanced Approved Approved Vesicles "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" Vesicles "HPA019105: AB_1850496, HPA019482: AB_1850498, HPA025238: " "unprognostic (5.74e-4)" "unprognostic (2.94e-2)" "unprognostic (6.58e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (2.76e-3)" "unprognostic (6.01e-4)" "unprognostic (2.52e-2)" "unprognostic (1.70e-1)" "unprognostic (9.04e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "prognostic unfavorable (4.81e-9)" "unprognostic (6.87e-2)" "unprognostic (2.04e-1)" "unprognostic (8.62e-2)" "unprognostic (3.91e-2)" HAPLN2 BRAL1 ENSG00000132702 "Hyaluronan and proteoglycan link protein 2" Q9GZV7 1 156619331-156625725 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 86 "brain: 617.5" "Cell type enriched" "Detected in some" 9 "Oligodendrocytes: 188.1" "Cancer enriched" "Detected in some" 10 "glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 2.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045765 Enhanced "Secreted in brain" "No annotated function" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 36 "HPA045765: AB_10964781" "unprognostic (3.19e-3)" "unprognostic (1.06e-1)" "unprognostic (1.02e-2)" "unprognostic (3.41e-1)" "unprognostic (1.88e-1)" "unprognostic (2.44e-1)" "unprognostic (1.92e-1)" "unprognostic (2.04e-3)" "unprognostic (1.31e-1)" "unprognostic (8.25e-2)" "unprognostic (5.54e-3)" "unprognostic (2.72e-2)" "unprognostic (2.70e-2)" "unprognostic (1.08e-1)" "unprognostic (2.25e-1)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" HAPLN3 "EXLD1, HsT19883" ENSG00000140511 "Hyaluronan and proteoglycan link protein 3" Q96S86 15 88877294-88895597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 1158.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 51.0" "Lineage enriched" "Detected in all" 5 "T-cells: 51.0" "Cancer enhanced" "Detected in many" "Uterine cancer: 52.1" "Colon - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039237 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA039237: AB_10805357" "unprognostic (1.67e-2)" "unprognostic (1.04e-3)" "unprognostic (2.57e-1)" "unprognostic (2.53e-2)" "unprognostic (3.27e-1)" "unprognostic (2.24e-2)" "unprognostic (4.21e-1)" "unprognostic (3.82e-1)" "unprognostic (3.37e-3)" "unprognostic (7.37e-3)" "unprognostic (1.13e-3)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.18e-13)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.12e-1)" HAPLN4 "BRAL2, KIAA1926" ENSG00000187664 "Hyaluronan and proteoglycan link protein 4" Q86UW8 19 19254756-19262804 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 45.5;intestine: 14.9;liver: 13.8" "Group enriched" "Detected in some" 9 "Excitatory neurons: 15.5;Inhibitory neurons: 19.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Kidney - Proximal tubular cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055856 Enhanced "Secreted in brain" "No annotated function" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 8: Neurons - Neuronal signaling" "HPA055856: AB_2682946" "unprognostic (3.36e-4)" HARS2 "HARSL, HARSR, HO3" ENSG00000112855 "Histidyl-tRNA synthetase 2, mitochondrial" P49590 5 140691430-140699305 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035941, HPA075303" Approved Approved Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA035941: AB_10671237, HPA075303: " "prognostic unfavorable (6.49e-4)" "unprognostic (3.15e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.79e-2)" "unprognostic (1.78e-1)" "unprognostic (8.30e-3)" "prognostic unfavorable (2.92e-4)" "unprognostic (7.77e-2)" "unprognostic (1.88e-1)" "unprognostic (5.26e-2)" "unprognostic (1.58e-1)" "unprognostic (2.68e-2)" "unprognostic (1.85e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (1.31e-2)" HBEGF "DTR, DTS, HEGFL" ENSG00000113070 "Heparin binding EGF like growth factor" Q99075 5 140332843-140346603 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 123.8" "Cell type enhanced" "Detected in many" "Macrophages: 223.9;monocytes: 315.2;Squamous epithelial cells: 297.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 1.6" "Group enriched" "Detected in many" 6 "dendritic cells: 1.6;monocytes: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053243 Uncertain "Secreted to blood" "Growth factor" NA NA 118000 "Cluster 40: Monocytes - Innate immune response" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 3 "HPA053243: AB_2682086" "unprognostic (3.64e-1)" "unprognostic (3.05e-1)" "unprognostic (4.31e-2)" "unprognostic (5.09e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (8.44e-3)" "unprognostic (3.51e-2)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (7.09e-4)" "prognostic favorable (6.00e-4)" "unprognostic (2.20e-2)" "unprognostic (6.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.54e-1)" "unprognostic (2.87e-2)" HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002946 Approved Enhanced Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 5 Mitochondria "HPA002946: AB_1079041" "prognostic unfavorable (8.69e-5)" "unprognostic (6.89e-3)" "unprognostic (8.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.44e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (9.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.52e-2)" "unprognostic (2.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (6.17e-8)" "unprognostic (2.66e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.93e-2)" HCRT "OX, PPOX" ENSG00000161610 "Hypocretin neuropeptide precursor" O43612 17 42184060-42185452 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1531 "brain: 441.9" "Cell type enhanced" "Detected in some" "B-cells: 1.5;Collecting duct cells: 1.9;Enteroendocrine cells: 1.9;Kupffer cells: 3.3;Oligodendrocyte precursor cells: 1.9;Pancreatic endocrine cells: 1.7" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Region enriched" "Detected in many" 8 "hypothalamus: 901.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "hypothalamus: 93.4" "Region enriched" "Detected in some" 60 "hypothalamus: 146.5" "HPA064801, CAB079778" Enhanced Supported "Secreted to blood" Neuropeptide NA NA "Cluster 32: Basophils - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 7: T-cells - T-cell receptor" "CAB079778: , HPA064801: " "unprognostic (3.34e-2)" "unprognostic (7.76e-5)" "unprognostic (3.21e-2)" "unprognostic (3.01e-2)" "unprognostic (2.20e-2)" "unprognostic (1.41e-1)" "unprognostic (1.23e-1)" HDGF HMG1L2 ENSG00000143321 "Heparin binding growth factor" P51858 1 156742109-156766925 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "DNA-binding, Growth factor, Heparin-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026035, HPA048728, HPA053422" Enhanced Enhanced Nucleoplasm "Secreted to blood" "Growth factor" NA NA 790000 "Cluster 29: Non-specific - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "CAB026035: , HPA048728: AB_2680503, HPA053422: AB_2682146" "unprognostic (2.80e-1)" "unprognostic (9.63e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (9.06e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (2.43e-8)" "unprognostic (9.80e-3)" "unprognostic (2.34e-2)" "prognostic favorable (9.84e-4)" "unprognostic (2.45e-3)" "unprognostic (3.67e-2)" "unprognostic (1.40e-3)" "unprognostic (8.66e-3)" "unprognostic (2.14e-1)" "unprognostic (2.06e-1)" "unprognostic (3.86e-2)" HDHD5 CECR5 ENSG00000069998 "Haloacid dehalogenase like hydrolase domain containing 5" Q9BXW7 22 17137511-17165287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005548 Approved Approved Mitochondria "Intracellular and membrane" "No annotated function" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA005548: AB_1078497" "unprognostic (4.04e-2)" "unprognostic (5.04e-2)" "unprognostic (4.54e-3)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (5.71e-2)" "unprognostic (1.04e-3)" "unprognostic (7.35e-2)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (5.76e-2)" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (7.07e-3)" "unprognostic (1.71e-1)" "unprognostic (1.20e-2)" "unprognostic (7.21e-3)" HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 251.5;Endothelial cells: 127.8;Mesothelial cells: 191.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "monocytes: 1.3;NK-cells: 2.1;T-cells: 1.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA 510000000 "Cluster 33: Non-specific - ATP binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Vesicles "Plasma membrane" "HPA010952: AB_2668389, HPA011559: AB_1850580" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.48e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (1.69e-1)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.11e-2)" "unprognostic (4.99e-2)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.16e-4)" HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340924-72376420 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 213.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018082, HPA054583" Supported Supported Vesicles,Cytosol "Intracellular and membrane" Enzyme NA NA 20000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles Cytosol "HPA018082: , HPA054583: AB_2682531" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (3.41e-1)" "prognostic favorable (5.63e-8)" "unprognostic (6.58e-2)" "unprognostic (1.32e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (3.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (9.98e-2)" "unprognostic (3.98e-1)" "unprognostic (7.05e-3)" "unprognostic (3.02e-2)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" HEXB ENSG00000049860 "Hexosaminidase subunit beta" P07686 5 74640023-74722647 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 458.7;Hofbauer cells: 316.0;Syncytiotrophoblasts: 508.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055409, HPA056010" Enhanced "Intracellular and membrane" Enzyme NA NA 40000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 25 "HPA055409: AB_2682808, HPA056010: AB_2683008" "unprognostic (3.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.85e-2)" "unprognostic (8.72e-2)" "unprognostic (1.12e-2)" "unprognostic (6.44e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (2.21e-1)" "unprognostic (5.01e-2)" "unprognostic (1.58e-3)" "unprognostic (6.45e-2)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (1.31e-2)" "unprognostic (9.67e-2)" "unprognostic (1.64e-2)" HGF "DFNB39, F-TCF, HGFB, HPTA, SF" ENSG00000019991 "Hepatocyte growth factor" P14210 7 81699010-81770438 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Serine protease homolog" "Cancer-related genes, Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "placenta: 301.5" "Cell type enhanced" "Detected in many" "Early spermatids: 18.7;Endometrial stromal cells: 21.8;Fibroblasts: 23.2;Inhibitory neurons: 21.6;monocytes: 22.1;Muller glia cells: 27.8;Smooth muscle cells: 64.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 94.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.6" "Cancer enhanced" "Detected in many" "Neuroblastoma: 101.3;Rhabdoid: 247.7" "Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010333, HPA040360, HPA044088" Approved "Secreted to blood" "Growth factor" NA NA 4110000 14000 "Cluster 46: Basophils - Proteolysis" "Cluster 58: Placenta - Pregnancy" "Cluster 24: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 2 "CAB010333: AB_647965, HPA040360: AB_2676939, HPA044088: AB_2678804" "unprognostic (5.24e-2)" "unprognostic (6.77e-2)" "unprognostic (1.72e-2)" "unprognostic (5.12e-2)" "unprognostic (1.85e-2)" "unprognostic (7.45e-5)" "unprognostic (1.66e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-2)" "unprognostic (2.97e-2)" "unprognostic (2.74e-1)" "unprognostic (5.29e-2)" "prognostic unfavorable (5.59e-4)" "unprognostic (7.90e-3)" "unprognostic (2.92e-2)" "unprognostic (1.14e-2)" "unprognostic (2.06e-2)" HGFAC "HGFA, HGFAP" ENSG00000109758 "HGF activator" Q04756 4 3441968-3449486 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "liver: 211.9" "Group enriched" "Detected in some" 5 "Early spermatids: 75.5;Hepatocytes: 55.8;Late spermatids: 163.2" "Cancer enriched" "Detected in some" 22 "liver cancer: 26.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058279, HPA059076" Enhanced "Secreted to blood" Enzyme NA NA 7590000 9300000000 "Cluster 31: Liver - Plasma proteins" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 11: Late spermatids - Unknown function" 4 "HPA058279: AB_2683665, HPA059076: AB_2683898" "unprognostic (2.70e-2)" "unprognostic (8.20e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-2)" "unprognostic (2.85e-3)" "unprognostic (5.37e-3)" "unprognostic (5.90e-2)" "unprognostic (1.81e-1)" "unprognostic (8.54e-3)" "unprognostic (5.52e-2)" "prognostic unfavorable (9.31e-4)" "unprognostic (2.87e-1)" "unprognostic (2.24e-1)" "unprognostic (9.49e-2)" "unprognostic (3.74e-4)" HHIP "FLJ20992, HIP" ENSG00000164161 "Hedgehog interacting protein" Q96QV1 4 144646156-144745271 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.1;lung: 15.7" "Group enriched" "Detected in some" 6 "Alveolar cells type 2: 291.5;Leydig cells: 142.1;Oligodendrocytes: 384.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 115.1" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012616 Uncertain Uncertain Nucleoplasm "Secreted in other tissues" "No annotated function" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Alveolar cells - Lung function" 1 Nucleoplasm "HPA012616: AB_1850687" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.02e-2)" "unprognostic (7.12e-3)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-1)" "unprognostic (1.95e-2)" "unprognostic (4.20e-1)" "unprognostic (1.90e-2)" "unprognostic (1.89e-1)" "unprognostic (9.66e-3)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" HHIPL1 KIAA1822 ENSG00000182218 "HHIP like 1" Q96JK4 14 99645129-99680569 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.5" "Cell type enhanced" "Detected in some" "Astrocytes: 31.6;Bipolar cells: 9.3;Excitatory neurons: 8.0;Inhibitory neurons: 11.7;Mesothelial cells: 7.9;Muller glia cells: 12.7;Oligodendrocyte precursor cells: 12.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.2" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Secreted in other tissues" "No annotated function" NA NA 120000 "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 47: Astrocytes - Unknown function" "unprognostic (6.16e-2)" "unprognostic (3.44e-2)" "unprognostic (3.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (2.75e-2)" "unprognostic (4.70e-3)" "unprognostic (6.68e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (1.35e-3)" "unprognostic (8.49e-6)" "unprognostic (2.52e-2)" "unprognostic (2.97e-1)" "unprognostic (2.70e-2)" "unprognostic (7.12e-6)" HHIPL2 "FLJ13840, KIAA1822L" ENSG00000143512 "HHIP like 2" Q6UWX4 1 222522258-222548104 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.7;thyroid gland: 1.9" "Group enriched" "Detected in some" 9 "Early spermatids: 14.2;Late spermatids: 26.9;Spermatocytes: 11.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059673 Enhanced Uncertain Mitochondria,Cytosol "Secreted in other tissues" "No annotated function" No NA "Cluster 78: Testis - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 Mitochondria Cytosol "HPA059673: AB_2684100" "unprognostic (1.35e-2)" "unprognostic (4.62e-3)" "unprognostic (2.91e-1)" "unprognostic (9.21e-2)" "unprognostic (3.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.74e-3)" "prognostic unfavorable (4.64e-4)" "unprognostic (8.07e-2)" "unprognostic (3.64e-1)" "unprognostic (2.29e-2)" "unprognostic (2.14e-2)" "unprognostic (0.00e+0)" "unprognostic (6.52e-2)" "unprognostic (4.21e-4)" "unprognostic (2.30e-3)" "unprognostic (8.38e-2)" HHLA1 PLA2L ENSG00000132297 "HERV-H LTR-associating 1" C9JL84 8 132061480-132111159 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 1.1;Oligodendrocyte precursor cells: 1.4;Oocytes: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" "No annotated function" NA NA "Cluster 34: Testis cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" "unprognostic (5.15e-2)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" HILPDA "C7orf68, FLJ21076, HIG-2, HIG2" ENSG00000135245 "Hypoxia inducible lipid droplet associated" Q9Y5L2 7 128455849-128458418 "Predicted membrane proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 159.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 166.6;Cytotrophoblasts: 123.2;Extravillous trophoblasts: 286.5;Ionocytes: 180.0;Syncytiotrophoblasts: 327.1" "Cancer enhanced" "Detected in all" "renal cancer: 72.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 67.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010515 Approved Supported "Nucleoplasm,Lipid droplets" "Intracellular and membrane" Other NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Lipid droplets" Nucleoplasm "HPA010515: AB_1850710" "unprognostic (1.10e-2)" "unprognostic (1.68e-2)" "unprognostic (1.88e-2)" "unprognostic (2.27e-1)" "unprognostic (2.10e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.30e-11)" "unprognostic (9.20e-3)" "unprognostic (4.07e-3)" "unprognostic (2.49e-1)" "unprognostic (4.06e-3)" "unprognostic (2.15e-2)" "prognostic unfavorable (2.05e-7)" "unprognostic (2.23e-2)" "unprognostic (2.77e-1)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 107.6;Hepatocytes: 88.1;Proximal tubular cells: 112.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria "Intracellular and membrane" Enzyme NA NA 110000 "Cluster 13: Non-specific - Mitochondria" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria "HPA020961: AB_1850715, HPA059109: AB_2683906" "unprognostic (9.64e-3)" "unprognostic (1.53e-2)" "unprognostic (3.02e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-1)" "unprognostic (2.38e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.71e-3)" "unprognostic (2.87e-2)" "prognostic favorable (2.97e-9)" "unprognostic (4.29e-2)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (1.72e-1)" HLA-C "D6S204, HLA-JY3, PSORS1" ENSG00000204525 "Major histocompatibility complex, class I, C" P10321 6 31268749-31272130 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1411.1" "Cell type enhanced" "Detected in all" "monocytes: 2864.5;NK-cells: 2895.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Thyroid - T-cells" "Intracellular and membrane" Immunity NA NA 240000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 14: Langerhans cells - Innate immune response" 6 "unprognostic (2.17e-1)" "unprognostic (3.38e-1)" "unprognostic (3.05e-2)" "unprognostic (4.42e-2)" "unprognostic (1.56e-1)" "unprognostic (2.08e-1)" "unprognostic (1.51e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-3)" "unprognostic (3.23e-3)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (2.34e-1)" "unprognostic (2.00e-1)" "unprognostic (8.12e-2)" "unprognostic (1.87e-2)" "unprognostic (7.16e-2)" HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2275.7;Endothelial cells: 1508.4;monocytes: 2383.9;NK-cells: 1828.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "CAB024589, HPA031454, CAB080329" Enhanced Supported "Vesicles,Plasma membrane" "Secreted to blood" Immunity NA NA 100000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 14: Langerhans cells - Innate immune response" 1 "Vesicles, Plasma membrane" "CAB024589: AB_324025, CAB080329: , HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" HLA-G ENSG00000204632 "Major histocompatibility complex, class I, G" P17693 6 29826967-29831125 "Cancer-related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Immunity "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 13.1;placenta: 10.7" "Cell type enriched" "Detected in many" 21 "Extravillous trophoblasts: 2180.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.1" "Testis - Late spermatids" CAB016158 Enhanced "Secreted to blood" Immunity NA NA 32800000 67000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Lung - Lung function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" 4 "CAB016158: AB_627938" "unprognostic (1.13e-2)" "unprognostic (9.95e-2)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (8.35e-2)" "unprognostic (1.35e-1)" "unprognostic (1.18e-3)" "unprognostic (2.51e-1)" "prognostic favorable (3.91e-5)" "unprognostic (6.34e-2)" "unprognostic (8.31e-2)" "unprognostic (1.78e-1)" "unprognostic (1.03e-2)" "unprognostic (6.56e-3)" "unprognostic (1.40e-1)" "unprognostic (1.52e-2)" "unprognostic (3.19e-3)" HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.7" "Cell type enhanced" "Detected in many" "Adipocytes: 37.7;Endothelial cells: 22.1;Fibroblasts: 22.5;Lymphatic endothelial cells: 35.5;Microglial cells: 42.9;Oocytes: 16.9;Salivary duct cells: 17.1;Schwann cells: 22.2" "Cancer enriched" "Detected in many" 6 "melanoma: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 64.8;skin cancer: 50.9" "Breast - Fibroblasts, Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 13.2" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" Other NA NA 9200000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 53: Fibroblasts - ECM organization" 1 "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: AB_2681572" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (8.00e-2)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.59e-7)" "unprognostic (1.22e-2)" "unprognostic (5.17e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-3)" HMCN2 "DKFZp434P0216, FLJ23816" ENSG00000148357 "Hemicentin 2" Q8NDA2 9 130265760-130434123 "Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 32.8;intestine: 49.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 12.6;Early spermatids: 13.9;Fibroblasts: 17.9;Late spermatids: 12.8;Proximal enterocytes: 34.9;Skeletal myocytes: 21.5;Smooth muscle cells: 9.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 9.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.4;Sarcoma: 3.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053903, HPA070647" Enhanced Approved Vesicles "Secreted to extracellular matrix" Other NA NA 27000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA053903: AB_2682301, HPA070647: AB_2686290" "unprognostic (1.61e-1)" "unprognostic (8.05e-3)" "unprognostic (1.69e-1)" "unprognostic (5.53e-4)" "unprognostic (1.05e-1)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "unprognostic (8.78e-3)" "unprognostic (3.23e-1)" "unprognostic (3.97e-4)" "unprognostic (3.36e-2)" "unprognostic (3.93e-1)" "unprognostic (1.04e-3)" "unprognostic (1.53e-2)" "unprognostic (3.62e-2)" "unprognostic (8.96e-3)" "unprognostic (8.63e-2)" HMGB1 "DKFZp686A04236, HMG1, HMG3, SBP-1" ENSG00000189403 "High mobility group box 1" P09429 13 30456704-30617597 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Autophagy, Chemotaxis, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "HPA003506, CAB005873, HPA073663" Supported Supported Nucleoplasm "Secreted to blood" Immunity NA NA 2800000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 52: Non-specific - Cell proliferation" 20 Nucleoplasm "CAB005873: AB_444360, HPA003506: AB_1079070, HPA073663: " "unprognostic (9.56e-2)" "unprognostic (1.34e-1)" "unprognostic (1.97e-2)" "unprognostic (1.07e-1)" "unprognostic (4.44e-2)" "unprognostic (4.29e-2)" "unprognostic (3.16e-2)" "unprognostic (4.33e-2)" "unprognostic (5.73e-2)" "unprognostic (1.73e-1)" "unprognostic (2.64e-2)" "unprognostic (2.30e-2)" "unprognostic (4.28e-3)" "unprognostic (5.22e-3)" "unprognostic (4.67e-1)" "unprognostic (9.13e-3)" "unprognostic (1.97e-2)" HMGB2 HMG2 ENSG00000164104 "High mobility group box 2" P26583 4 173331376-173334432 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, DNA recombination, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "bone marrow: 2317.3;lymphoid tissue: 914.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 1571.7;Extravillous trophoblasts: 938.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 802.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003506, CAB037206, HPA053314, HPA073663" Enhanced Supported Nucleoplasm,Nucleoli "Secreted to blood" Transcription NA Yes 1200000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 52: Non-specific - Cell proliferation" 10 Nucleoplasm Nucleoli "CAB037206: AB_1079071, HPA003506: AB_1079070, HPA053314: AB_2682109, HPA073663: " "unprognostic (2.82e-1)" "unprognostic (8.52e-3)" "unprognostic (2.56e-1)" "unprognostic (8.37e-2)" "unprognostic (8.05e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (3.76e-5)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.13e-4)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (9.65e-2)" "prognostic unfavorable (7.60e-12)" "unprognostic (1.60e-2)" "unprognostic (2.83e-2)" "unprognostic (2.68e-2)" "unprognostic (1.21e-2)" HMGCL HL ENSG00000117305 "3-hydroxy-3-methylglutaryl-CoA lyase" P35914 1 23801885-23838620 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 170.4;Proximal tubular cells: 194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004727 Enhanced "Intracellular and membrane" Enzyme NA NA 34000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "HPA004727: AB_1079074" "unprognostic (8.24e-2)" "unprognostic (3.21e-2)" "prognostic favorable (7.67e-4)" "unprognostic (1.23e-3)" "unprognostic (5.47e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (3.05e-1)" "unprognostic (8.24e-2)" "prognostic favorable (5.07e-8)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (8.60e-2)" "unprognostic (3.39e-3)" HMSD "ACC-6, ACC6, C18orf53" ENSG00000221887 "Histocompatibility minor serpin domain containing" "A8MTL9, P0C7T4" 18 63949301-63981774 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "brain: 30.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 8.7;Basal respiratory cells: 4.0;dendritic cells: 6.0;Oligodendrocytes: 10.4;Spermatogonia: 8.9" "Cancer enhanced" "Detected in single" "cervical cancer: 1.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 19 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.8" "Cancer enhanced" "Detected in many" "lymphoma: 7.3" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 14: Langerhans cells - Innate immune response" "unprognostic (5.83e-3)" "unprognostic (1.40e-1)" "unprognostic (1.40e-2)" "unprognostic (5.42e-3)" "unprognostic (6.20e-2)" "unprognostic (1.16e-2)" "unprognostic (4.91e-2)" "unprognostic (3.80e-1)" "unprognostic (1.41e-2)" "unprognostic (5.19e-3)" "unprognostic (8.67e-2)" "unprognostic (1.44e-1)" "unprognostic (7.14e-6)" "unprognostic (1.22e-1)" "unprognostic (2.85e-1)" "unprognostic (1.45e-3)" "unprognostic (3.55e-1)" HNRNPA2B1 HNRPA2B1 ENSG00000122566 "Heterogeneous nuclear ribonucleoprotein A2/B1" P22626 7 26171151-26201529 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Transport" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001666, HPA005812, CAB012403, HPA065537" Supported Supported Nucleoplasm "Intracellular and membrane" Transport NA NA 11000000 "Cluster 30: Non-specific - DNA binding" "Cluster 66: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 80: Non-specific - Transcription" 5 Nucleoplasm "CAB012403: , HPA001666: AB_1850836, HPA005812: AB_2667441, HPA065537: AB_2685507" "unprognostic (1.19e-1)" "unprognostic (4.45e-1)" "unprognostic (2.33e-1)" "unprognostic (6.39e-2)" "unprognostic (5.64e-2)" "unprognostic (8.04e-3)" "prognostic unfavorable (1.03e-6)" "unprognostic (1.25e-2)" "unprognostic (9.12e-3)" "unprognostic (4.35e-3)" "unprognostic (1.31e-1)" "prognostic unfavorable (5.12e-4)" "prognostic unfavorable (8.01e-5)" "unprognostic (6.74e-2)" "unprognostic (3.36e-2)" "unprognostic (2.02e-1)" "unprognostic (1.56e-2)" HP ENSG00000257017 Haptoglobin P00738 16 72054505-72061055 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Acute phase, Immunity" "Antibiotic, Antimicrobial, Antioxidant, Serine protease homolog" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 85 "liver: 54575.6" "Group enriched" "Detected in many" 45 "Hepatocytes: 52816.7;Mesothelial cells: 16337.1" "Cancer enriched" "Detected in many" 81 "liver cancer: 1297.4" "Region enhanced" "Detected in all" "medulla oblongata: 56.4" "Group enriched" "Detected in many" 5 "classical monocyte: 49.5;eosinophil: 80.5" "Group enriched" "Detected in many" 7 "granulocytes: 80.5;monocytes: 49.5" "Group enriched" "Detected in some" 12 "Gastric cancer: 6.6;Leukemia: 4.1;liver cancer: 15.7" "Liver - Hepatocytes" "CAB003787, HPA047750, HPA066795" Enhanced Approved Vesicles "Secreted to blood" "Acute phase" NA NA 998000000000 100000000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 31: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 3 Vesicles "CAB003787: , HPA047750: AB_2680146, HPA066795: " "unprognostic (6.38e-3)" "unprognostic (7.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.41e-2)" "unprognostic (2.34e-3)" "unprognostic (2.07e-1)" "unprognostic (7.79e-3)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "prognostic unfavorable (6.94e-13)" "unprognostic (4.34e-4)" "unprognostic (1.80e-1)" "unprognostic (6.61e-2)" "unprognostic (2.49e-2)" HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063148-72077246 "Enzymes, Plasma proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 786.9" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 205.7" "Cancer enriched" "Detected in some" 53 "liver cancer: 185.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "liver cancer: 2.3;prostate cancer: 3.5" "Liver - Hepatocytes" HPA047750 Supported Approved Vesicles "Secreted to blood" Other NA NA 49000000000 55000000000 "Cluster 83: Liver - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 15: Non-specific - Mixed function" Vesicles "HPA047750: AB_2680146" "unprognostic (2.43e-1)" "unprognostic (4.69e-2)" "unprognostic (5.97e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (8.21e-2)" "unprognostic (2.30e-1)" "unprognostic (3.44e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 32.7;Kupffer cells: 37.4;Macrophages: 21.1;Suprabasal keratinocytes: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.6" "Group enriched" "Detected in many" 4 "granulocytes: 18.6;monocytes: 27.2" "Low cancer specificity" "Detected in all" "Breast - Macrophages" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" "Cell adhesion" No No 6500000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" HPSE2 "HPA2, HPR2, UFS" ENSG00000172987 "Heparanase 2 (inactive)" Q8WWQ2 10 98457077-99235862 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.0;cervix: 35.5;vagina: 26.7" "Cell type enriched" "Detected in some" 9 "Astrocytes: 854.3" "Cancer enhanced" "Detected in some" "prostate cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Leukemia: 7.4;prostate cancer: 2.1" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044603 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Astrocytes - Unknown function" "HPA044603: AB_10794051" "unprognostic (2.44e-1)" "unprognostic (4.28e-3)" "unprognostic (4.83e-3)" "unprognostic (6.00e-2)" "unprognostic (1.15e-1)" "unprognostic (1.59e-1)" "unprognostic (3.05e-2)" "unprognostic (1.82e-2)" "unprognostic (4.03e-2)" "unprognostic (7.94e-2)" "unprognostic (1.38e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-4)" "unprognostic (5.79e-2)" "unprognostic (2.51e-1)" "unprognostic (9.39e-3)" "unprognostic (6.13e-3)" HPX ENSG00000110169 Hemopexin P02790 11 6431049-6442617 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 886 "liver: 5126.7" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 4942.9" "Cancer enriched" "Detected in many" 79 "liver cancer: 571.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 9.0" "Breast - Breast glandular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016725, HPA065318, HPA068847" Approved "Secreted to blood" Transport NA NA 425000000000 190000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "CAB016725: , HPA065318: , HPA068847: " "unprognostic (3.39e-2)" "unprognostic (9.26e-2)" "unprognostic (3.88e-1)" "unprognostic (6.19e-4)" "unprognostic (2.05e-2)" "unprognostic (2.41e-1)" "prognostic favorable (2.26e-4)" "unprognostic (6.33e-2)" "unprognostic (5.67e-3)" "unprognostic (3.88e-1)" "unprognostic (5.08e-3)" "unprognostic (2.78e-2)" "unprognostic (5.82e-12)" "unprognostic (2.01e-1)" "unprognostic (4.48e-1)" "unprognostic (1.84e-2)" "unprognostic (2.14e-2)" HRC MGC133236 ENSG00000130528 "Histidine rich calcium binding protein" P23327 19 49151198-49155396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 50 "heart muscle: 695.2;skeletal muscle: 436.8;tongue: 234.9" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 2388.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Myeloma: 7.7;Rhabdoid: 2.9;Sarcoma: 5.7" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA004833 Enhanced "Intracellular and membrane" "No annotated function" NA NA 100000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" 2 "HPA004833: AB_1079083" "unprognostic (1.06e-1)" "unprognostic (1.04e-3)" "unprognostic (1.46e-2)" "unprognostic (4.94e-2)" "unprognostic (5.66e-2)" "unprognostic (9.75e-3)" "unprognostic (3.44e-1)" "unprognostic (1.74e-1)" "unprognostic (4.09e-1)" "unprognostic (1.62e-1)" "unprognostic (7.41e-3)" "unprognostic (5.85e-3)" "unprognostic (4.04e-2)" "unprognostic (6.68e-2)" "unprognostic (1.07e-1)" "unprognostic (1.86e-1)" "unprognostic (1.46e-1)" HRG "HPRG, HRGP" ENSG00000113905 "Histidine rich glycoprotein" P04196 3 186660216-186678234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Blood coagulation, Chemotaxis, Fibrinolysis, Hemostasis" Heparin-binding "Disease variant, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 174 "liver: 5270.7" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 396.9" "Cancer enriched" "Detected in some" 262 "liver cancer: 406.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050269, HPA054598" Supported "Secreted to blood" "Blood coagulation" NA NA 120000000000 28000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 2 "HPA050269: AB_2681068, HPA054598: AB_2682539" "unprognostic (2.67e-1)" "unprognostic (1.74e-2)" "unprognostic (7.58e-5)" "prognostic favorable (9.64e-5)" "unprognostic (1.44e-1)" "unprognostic (2.98e-3)" "unprognostic (2.22e-1)" "unprognostic (1.55e-2)" "unprognostic (1.14e-1)" "unprognostic (5.50e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-2)" HS2ST1 KIAA0448 ENSG00000153936 "Heparan sulfate 2-O-sulfotransferase 1" Q7LGA3 1 86914635-87109982 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 152.7;Excitatory neurons: 121.8;Inhibitory neurons: 124.6;Oligodendrocyte precursor cells: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043069, HPA043603, HPA075001" Supported Approved Mitochondria "Intracellular and membrane" Enzyme No No "Cluster 34: B-cells - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 47: Astrocytes - Unknown function" Mitochondria "HPA043069: AB_10964127, HPA043603: AB_10963432, HPA075001: AB_2686726" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (1.28e-3)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (7.20e-2)" "unprognostic (5.34e-2)" "unprognostic (7.70e-2)" "unprognostic (1.70e-3)" "unprognostic (1.45e-1)" "unprognostic (5.80e-2)" "unprognostic (1.63e-2)" "unprognostic (5.07e-2)" "unprognostic (3.24e-1)" "unprognostic (7.58e-2)" HS3ST1 3OST1 ENSG00000002587 "Heparan sulfate-glucosamine 3-sulfotransferase 1" O14792 4 11393150-11429564 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 30.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 147.6;Ionocytes: 127.4;Lymphatic endothelial cells: 98.3;Ovarian stromal cells: 172.3;Peritubular cells: 88.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 36 "memory B-cell: 15.0;naive B-cell: 26.7;plasmacytoid DC: 42.5" "Group enriched" "Detected in many" 110 "B-cells: 26.7;dendritic cells: 42.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 29.8" "Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002237 Approved Approved Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 6: Ovarian stromal cells - Transcription" Vesicles "HPA002237: AB_1079085" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (4.01e-2)" "prognostic favorable (7.73e-4)" "unprognostic (3.32e-2)" "unprognostic (8.90e-3)" "unprognostic (4.21e-1)" "unprognostic (2.08e-1)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "prognostic favorable (5.99e-8)" "unprognostic (9.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "prognostic favorable (8.67e-4)" HS6ST1 HS6ST ENSG00000136720 "Heparan sulfate 6-O-sulfotransferase 1" O60243 2 128236716-128318868 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 73.1;granulocytes: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044586 Approved Nucleoplasm "Intracellular and membrane" Enzyme NA NA 72000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 30: Granulocytes - Unknown function" 2 Nucleoplasm "HPA044586: AB_10963057" "unprognostic (9.94e-2)" "unprognostic (8.93e-3)" "unprognostic (4.94e-3)" "unprognostic (6.69e-3)" "unprognostic (1.99e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-2)" "unprognostic (3.21e-2)" "unprognostic (2.87e-1)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (4.28e-2)" "unprognostic (1.21e-2)" "unprognostic (2.77e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.66e-2)" HS6ST2 HS6ST-2 ENSG00000171004 "Heparan sulfate 6-O-sulfotransferase 2" Q96MM7 X 132626015-132961395 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.4;kidney: 15.3;ovary: 15.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.8;Excitatory neurons: 36.3;Inhibitory neurons: 42.4;Leydig cells: 60.8;Oligodendrocyte precursor cells: 50.9;Peritubular cells: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Ascending Loop of Henle cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034625 Uncertain Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus" "Plasma membrane" "HPA034625: AB_10612119" "unprognostic (7.62e-3)" "unprognostic (4.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.41e-1)" "unprognostic (3.24e-1)" "unprognostic (5.54e-2)" "unprognostic (1.44e-1)" "unprognostic (1.71e-2)" "unprognostic (1.14e-2)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-1)" "unprognostic (8.39e-5)" "unprognostic (1.36e-3)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.03e-4)" HS6ST3 ENSG00000185352 "Heparan sulfate 6-O-sulfotransferase 3" Q8IZP7 13 96090107-96839562 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 16.7" "Group enriched" "Detected in some" 27 "Excitatory neurons: 1266.4;Inhibitory neurons: 859.7;Oligodendrocyte precursor cells: 908.9" "Cancer enhanced" "Detected in many" "breast cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.2;Neuroblastoma: 3.3" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA078257 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments" "Intracellular and membrane" Enzyme NA NA 24000 "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Nuclear membrane" "Plasma membrane, Actin filaments" "HPA078257: AB_2732374" "unprognostic (2.34e-2)" "unprognostic (1.90e-2)" "unprognostic (2.82e-2)" "unprognostic (1.72e-2)" "unprognostic (4.88e-2)" "unprognostic (2.78e-2)" "unprognostic (1.55e-1)" "unprognostic (3.67e-3)" "unprognostic (8.11e-3)" "unprognostic (1.19e-1)" "prognostic favorable (6.12e-5)" "unprognostic (1.54e-4)" "unprognostic (2.24e-1)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 86.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" Vesicles "HPA049078: AB_2680622" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-3)" "unprognostic (5.26e-2)" "unprognostic (9.37e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-3)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (4.52e-1)" "unprognostic (1.73e-2)" HSD17B11 "17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2" ENSG00000198189 "Hydroxysteroid 17-beta dehydrogenase 11" Q8NBQ5 4 87336515-87391188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 280.6;liver: 234.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 360.6;Distal enterocytes: 353.9;Paneth cells: 458.7;Proximal enterocytes: 1083.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 772.2" "Group enriched" "Detected in all" 4 "granulocytes: 772.2;monocytes: 202.3" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021608 Enhanced Supported "Lipid droplets" "Intracellular and membrane" Enzyme NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 5: Enterocytes - Absorption" 54 "Lipid droplets" "HPA021608: AB_1847660" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.14e-2)" "unprognostic (9.68e-2)" "unprognostic (1.92e-1)" "unprognostic (3.35e-1)" "unprognostic (3.70e-2)" "unprognostic (1.78e-1)" "unprognostic (8.53e-2)" "unprognostic (1.24e-3)" "unprognostic (1.83e-1)" "unprognostic (2.65e-3)" "unprognostic (5.53e-2)" "unprognostic (2.13e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-2)" HSP90AB1 "HSPC2, HSPCB" ENSG00000096384 "Heat shock protein 90 alpha family class B member 1" P08238 6 44246166-44253888 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005230, HPA055729, HPA072606, HPA074351" Enhanced Supported Cytosol "Intracellular and membrane" Other NA Yes 63000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 80: Non-specific - Transcription" 137 Cytosol "CAB005230: AB_2121392, HPA055729: AB_2682899, HPA072606: AB_2732203, HPA074351: AB_2732252" "unprognostic (6.12e-3)" "unprognostic (2.96e-3)" "unprognostic (4.72e-2)" "unprognostic (9.24e-2)" "unprognostic (4.20e-1)" "unprognostic (1.15e-3)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "unprognostic (7.97e-2)" "prognostic favorable (4.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (3.02e-1)" "unprognostic (9.53e-2)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" HSP90B1 "GP96, GRP94, TRA1" ENSG00000166598 "Heat shock protein 90 beta family member 1" P14625 12 103930107-103953931 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 4886.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003901, CAB005224, HPA008424, CAB078151" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA 330000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 5 "Endoplasmic reticulum" "CAB005224: AB_2119181, CAB078151: AB_2665765, HPA003901: AB_1851181, HPA008424: AB_1851184" "unprognostic (1.03e-1)" "unprognostic (3.44e-2)" "unprognostic (1.18e-1)" "unprognostic (5.70e-2)" "unprognostic (1.17e-2)" "unprognostic (7.14e-3)" "unprognostic (3.00e-2)" "unprognostic (7.22e-2)" "unprognostic (8.77e-2)" "unprognostic (8.30e-2)" "unprognostic (2.76e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.03e-10)" "unprognostic (2.95e-1)" "unprognostic (2.39e-1)" "unprognostic (1.24e-1)" "unprognostic (1.28e-2)" HSPA13 STCH ENSG00000155304 "Heat shock protein family A (Hsp70) member 13" P48723 21 14371115-14383484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 128.9;Syncytiotrophoblasts: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014797 Approved "Intracellular and membrane" "No annotated function" NA NA 3300000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 6 "HPA014797: AB_1857567" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.77e-3)" "unprognostic (1.06e-1)" "unprognostic (1.72e-1)" "unprognostic (2.85e-3)" "unprognostic (1.41e-2)" "unprognostic (7.86e-2)" "unprognostic (1.64e-1)" "unprognostic (2.46e-1)" "unprognostic (5.62e-2)" "unprognostic (1.52e-2)" "unprognostic (1.65e-1)" "unprognostic (2.29e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-2)" HSPA1A "HSP70-1, HSPA1" ENSG00000204389 "Heat shock protein family A (Hsp70) member 1A" P0DMV8 6 31815543-31817946 "Disease related genes, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Langerhans cells: 3033.1;Skeletal myocytes: 2522.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 6.9;monocytes: 3.6;T-cells: 3.1" "Cancer enhanced" "Detected in many" "cervical cancer: 45.8" "CAB017451, CAB032815, HPA052504" Supported Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" Receptor NA Yes 47000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 80: Non-specific - Transcription" 7 "Nucleoplasm, Vesicles" Cytosol "CAB017451: AB_10013742, CAB032815: AB_627759, HPA052504: AB_2681854" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.98e-1)" "unprognostic (1.18e-2)" "unprognostic (6.17e-3)" "unprognostic (2.47e-2)" "unprognostic (1.74e-2)" "unprognostic (8.43e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" "unprognostic (6.48e-2)" "unprognostic (4.12e-2)" "unprognostic (1.51e-1)" HSPA5 "BiP, GRP78" ENSG00000044574 "Heat shock protein family A (Hsp70) member 5" P11021 9 125234853-125241382 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 1312.2;Syncytiotrophoblasts: 1441.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005221, HPA038845, HPA038846" Enhanced Approved Cytosol "Intracellular and membrane" Enzyme NA NA 790000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 6: Bone marrow - Innate immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 22 Cytosol "CAB005221: AB_631616, HPA038845: AB_10673477, HPA038846: AB_10673478" "unprognostic (3.98e-2)" "unprognostic (2.50e-3)" "unprognostic (6.64e-2)" "unprognostic (9.60e-3)" "unprognostic (1.54e-3)" "unprognostic (6.02e-3)" "unprognostic (9.08e-3)" "unprognostic (9.11e-3)" "unprognostic (4.50e-2)" "unprognostic (7.45e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.03e-1)" "unprognostic (1.34e-1)" "unprognostic (7.28e-2)" "unprognostic (3.66e-2)" HSPB6 "FLJ32389, Hsp20, PPP1R91" ENSG00000004776 "Heat shock protein family B (small) member 6" O14558 19 35754566-35758079 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 2865.7;tongue: 1690.4" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 176.4;Fibroblasts: 172.1;Leydig cells: 261.6;Ovarian stromal cells: 112.8;Peritubular cells: 218.2;Skeletal myocytes: 400.1;Smooth muscle cells: 207.3" "Cancer enhanced" "Detected in all" "stomach cancer: 93.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 63.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001974, HPA044153, HPA054811" Enhanced Supported "Nuclear speckles,Mitochondria,Cytosol" "Intracellular and membrane" Other NA NA 310000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 "Mitochondria, Cytosol" "Nuclear speckles" "CAB001974: , HPA044153: AB_2678836, HPA054811: AB_2682610" "unprognostic (3.19e-2)" "unprognostic (8.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.01e-1)" "unprognostic (5.21e-3)" "unprognostic (7.02e-2)" "unprognostic (9.67e-2)" "unprognostic (7.57e-2)" "unprognostic (1.18e-1)" "unprognostic (7.23e-2)" "unprognostic (1.20e-1)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.32e-2)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (1.43e-6)" HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 351.7;Endothelial cells: 288.6;Fibroblasts: 185.2;Schwann cells: 190.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Developmental protein" NA NA 1400000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" HTN1 HIS1 ENSG00000126550 "Histatin 1" P15515 4 70050438-70058848 "Predicted secreted proteins, Transporters" Biomineralization "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 2616 "salivary gland: 47123.7" "Cell type enriched" "Detected in some" 37 "Serous glandular cells: 83897.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 23 "skin cancer: 2.3" HPA077315 Approved "Secreted to digestive system" Defense NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "HPA077315: " "unprognostic (2.22e-1)" HTN3 HIS2 ENSG00000205649 "Histatin 3" P15516 4 70028455-70036538 "Predicted secreted proteins, Transporters" Biomineralization "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1103 "salivary gland: 131918.2" "Cell type enriched" "Detected in some" 36 "Serous glandular cells: 245289.6" "Cancer enhanced" "Detected in single" "melanoma: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 3.8" CAB073541 Enhanced "Secreted to digestive system" Defense NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "CAB073541: " HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 771.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 237.9;Mesothelial cells: 419.8;Muller glia cells: 335.4;Ovarian stromal cells: 227.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Podocytes, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" Enzyme NA NA 24800000 7600000 "Cluster 64: Neuronal - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 188.5" "Group enriched" "Detected in many" 5 "Fibroblasts: 138.9;Leydig cells: 43.9;Ovarian stromal cells: 45.0;Peritubular cells: 40.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Region enhanced" "Detected in many" "choroid plexus: 9.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 26.5" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 13.5" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" Enzyme NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 4 Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" HTRA4 FLJ90724 ENSG00000169495 "HtrA serine peptidase 4" P83105 8 38974228-38988663 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 64.5" "Cell type enriched" "Detected in some" 12 "Extravillous trophoblasts: 534.7" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "testis cancer: 8.8" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in all" HPA045402 Enhanced "Secreted in female reproductive system" Enzyme NA NA 23000 "Cluster 24: Non-specific - Transcription" "Cluster 58: Placenta - Pregnancy" "Cluster 9: Non-specific - Receptor signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" 5 "HPA045402: AB_2679316" "unprognostic (1.20e-1)" "unprognostic (5.83e-4)" "unprognostic (8.02e-2)" "unprognostic (2.13e-2)" "unprognostic (8.20e-2)" "unprognostic (2.42e-2)" "unprognostic (1.80e-1)" "unprognostic (7.40e-3)" "unprognostic (1.40e-1)" "unprognostic (5.14e-4)" "unprognostic (1.01e-1)" "unprognostic (8.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.58e-1)" "unprognostic (5.19e-3)" "unprognostic (2.39e-3)" "unprognostic (1.19e-3)" HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 196.6;lymphoid tissue: 92.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 25.1;Hepatocytes: 119.5;Proximal tubular cells: 49.9" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.3" "Cancer enhanced" "Detected in many" "liver cancer: 17.4" "Colon - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Endothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" Enzyme NA NA 590000 "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 18: Liver cancer - Metabolism" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" HYAL3 "LUCA-3, LUCA14, Minna14" ENSG00000186792 "Hyaluronidase 3" O43820 3 50292831-50299405 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 273.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 33.2;eosinophil: 54.7" "Lineage enriched" "Detected in all" 7 "granulocytes: 54.7" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA049402 Uncertain "Secreted to blood" Enzyme NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 6: Bone marrow - Innate immune response" "Cluster 37: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 63: Late spermatids - Spermatogenesis" 2 "HPA049402: AB_2680746" "unprognostic (1.21e-3)" "unprognostic (2.55e-2)" "unprognostic (5.45e-2)" "unprognostic (8.19e-2)" "unprognostic (3.07e-1)" "unprognostic (1.65e-2)" "unprognostic (7.98e-3)" "unprognostic (7.36e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" "unprognostic (5.40e-2)" "unprognostic (5.71e-2)" "unprognostic (2.61e-1)" "unprognostic (8.09e-2)" "unprognostic (1.28e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.12e-5)" HYOU1 "Grp170, HSP12A, ORP150" ENSG00000149428 "Hypoxia up-regulated 1" Q9Y4L1 11 119044188-119057227 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Stress response" Chaperone "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 128.3;Plasma cells: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049296 Approved "Intracellular and membrane" Other NA NA 130000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 2 "HPA049296: AB_2680702" "unprognostic (2.97e-2)" "unprognostic (2.48e-2)" "unprognostic (8.46e-2)" "prognostic favorable (2.58e-4)" "unprognostic (2.19e-1)" "unprognostic (1.35e-2)" "unprognostic (1.61e-3)" "unprognostic (1.81e-1)" "unprognostic (8.98e-2)" "unprognostic (7.93e-2)" "unprognostic (2.01e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (5.10e-5)" "unprognostic (3.86e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (5.00e-4)" "unprognostic (1.38e-2)" IAPP "AMYLIN, DAP, IAP" ENSG00000121351 "Islet amyloid polypeptide" P10997 12 21354959-21379980 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "pancreas: 161.3" "Cell type enriched" "Detected in some" 7 "Pancreatic endocrine cells: 487.3" "Cancer enriched" "Detected in single" 76 "pancreatic cancer: 21.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.4;thyroid cancer: 1.6" "Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "CAB000352, HPA053194" Enhanced Approved Vesicles "Secreted to blood" Hormone NA NA 11900 "Cluster 15: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 18: Early spermatids - Unknown function" 2 Vesicles "CAB000352: AB_2121635, HPA053194: AB_2682076" "unprognostic (5.52e-3)" "unprognostic (1.00e-1)" "unprognostic (4.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.91e-1)" IBSP "BSP, BSP-II, SP-II" ENSG00000029559 "Integrin binding sialoprotein" P21815 4 87799554-87812435 "Cancer-related genes, Predicted secreted proteins" "Biomineralization, Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pituitary gland: 1.9" "Cell type enriched" "Detected in single" 11 "Hofbauer cells: 6.6" "Group enriched" "Detected in many" 4 "breast cancer: 3.8;glioma: 12.2" "Region enhanced" "Detected in some" "thalamus: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Cell adhesion" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 58: Macrophages - Innate immune response" 1 "unprognostic (2.53e-2)" "unprognostic (3.55e-2)" "unprognostic (1.49e-2)" "unprognostic (3.93e-1)" "unprognostic (3.75e-2)" "unprognostic (9.48e-3)" "unprognostic (1.03e-3)" "unprognostic (4.07e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-11)" "unprognostic (6.20e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-3)" "unprognostic (2.11e-1)" ICAM4 "CD242, LW" ENSG00000105371 "Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)" Q14773 19 10286955-10288522 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Blood group antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 13.2;lung: 9.0" "Cell type enhanced" "Detected in many" "Adipocytes: 25.1;Alveolar cells type 2: 83.9;Endothelial cells: 21.3;Erythroid cells: 33.2;monocytes: 31.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "non-classical monocyte: 216.1" "Lineage enriched" "Detected in many" 7 "monocytes: 216.1" "Cancer enriched" "Detected in many" 5 "Leukemia: 35.5" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.3;lymphoid tissue: 19.6" "Cell type enriched" "Detected in some" 16 "T-cells: 96.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.2" "Lineage enriched" "Detected in single" 54 "T-cells: 29.2" "Cancer enhanced" "Detected in some" "Leukemia: 2.4;lymphoma: 2.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells, Testis - Spermatogonia, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" "No annotated function" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" ID1 "bHLHb24, dJ857M17.1.2" ENSG00000125968 "Inhibitor of DNA binding 1" P41134 20 31605283-31606515 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1528.2;Basal respiratory cells: 1392.0;Paneth cells: 1064.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025915, HPA058518, HPA068861" Approved Enhanced Nucleoplasm "Intracellular and membrane" "Developmental protein" NA No "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 13 Nucleoplasm "CAB025915: , HPA058518: AB_2683740, HPA068861: " "unprognostic (3.89e-2)" "unprognostic (3.45e-2)" "unprognostic (2.62e-2)" "unprognostic (3.19e-2)" "unprognostic (1.27e-2)" "unprognostic (1.74e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.85e-4)" "unprognostic (2.29e-1)" "unprognostic (1.58e-1)" "unprognostic (2.14e-2)" "unprognostic (7.83e-2)" "unprognostic (1.67e-2)" "unprognostic (1.71e-3)" "unprognostic (2.97e-1)" "unprognostic (6.17e-3)" "unprognostic (3.41e-3)" IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574096 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Secreted in other tissues" Receptor NA NA 310000 "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 3 "HPA063478: AB_2685020" "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favorable (3.69e-4)" "prognostic favorable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" IDS "ID2S, SIDS" ENSG00000010404 "Iduronate 2-sulfatase" P22304 X 149476988-149521096 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 433.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 224.4;granulocytes: 153.4;Inhibitory neurons: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078003 Approved "Intracellular and membrane" Enzyme NA NA 17000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "HPA078003: " "unprognostic (9.88e-2)" "unprognostic (1.10e-2)" "unprognostic (6.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (4.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.71e-2)" "unprognostic (1.42e-1)" "unprognostic (9.76e-3)" "unprognostic (3.61e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" IDUA "MPS1, MPSI" ENSG00000127415 Alpha-L-iduronidase P35475 4 986997-1004564 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025901, HPA046979, HPA054254" Enhanced Supported Vesicles "Intracellular and membrane" Enzyme NA NA 170000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 77: Plasma cells - Protein processing" Vesicles "CAB025901: , HPA046979: AB_2679888, HPA054254: AB_2682429" "unprognostic (3.62e-2)" "unprognostic (9.08e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-2)" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-2)" "unprognostic (1.89e-3)" "unprognostic (2.64e-2)" "unprognostic (4.61e-3)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.24e-1)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "prognostic favorable (8.04e-5)" IFI27L2 "FAM14A, TLH29" ENSG00000119632 "Interferon alpha inducible protein 27 like 2" Q9H2X8 14 94127779-94130253 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" HPA049588 Approved Nucleoli,Cytosol "Intracellular and membrane" Other No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 6: Ovarian stromal cells - Transcription" Cytosol Nucleoli "HPA049588: " "unprognostic (9.70e-3)" "unprognostic (2.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.76e-1)" "unprognostic (2.45e-1)" "unprognostic (2.80e-2)" "unprognostic (7.46e-3)" "unprognostic (4.76e-2)" "unprognostic (4.69e-2)" "unprognostic (1.58e-2)" "unprognostic (4.79e-3)" "unprognostic (3.96e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (3.88e-1)" "unprognostic (5.09e-2)" "unprognostic (3.52e-2)" IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 554.6;lymphoid tissue: 688.9" "Group enriched" "Detected in many" 4 "Hofbauer cells: 205.3;Kupffer cells: 132.8;Langerhans cells: 136.5;Macrophages: 255.7;monocytes: 168.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9529.3;eosinophil: 3901.6;intermediate monocyte: 14264.3;myeloid DC: 5706.8;non-classical monocyte: 9916.5" "Group enriched" "Detected in all" 8 "dendritic cells: 5706.8;granulocytes: 3901.6;monocytes: 14264.3" "Cancer enhanced" "Detected in all" "lymphoma: 572.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" Immunity NA NA 110000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" 3 "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" IFI35 IFP35 ENSG00000068079 "Interferon induced protein 35" P80217 17 43006740-43014456 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 132.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003283, HPA045946, HPA075580" Approved Supported Nucleoplasm,Nucleoli,Cytosol "Secreted to blood" Immunity NA NA 120000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 47: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 1 "Nucleoplasm, Cytosol" Nucleoli "HPA003283: , HPA045946: AB_2679509, HPA075580: " "prognostic favorable (1.41e-4)" "unprognostic (1.14e-2)" "unprognostic (1.82e-1)" "unprognostic (2.16e-1)" "unprognostic (1.32e-1)" "unprognostic (3.26e-1)" "unprognostic (3.90e-3)" "unprognostic (1.14e-1)" "unprognostic (6.92e-2)" "unprognostic (9.78e-3)" "unprognostic (6.51e-3)" "unprognostic (1.22e-1)" "prognostic unfavorable (4.03e-5)" "unprognostic (3.55e-1)" "unprognostic (3.62e-2)" "unprognostic (1.34e-2)" "unprognostic (1.49e-1)" IFNA1 "IFL, IFN, IFN-ALPHA, IFN-alphaD, IFNA@, IFNA13" ENSG00000197919 "Interferon alpha 1" P01562 9 21440439-21441316 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.1" HPA047557 Uncertain "Secreted to blood" Interferon NA NA 10000 "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" 1 "HPA047557: AB_2680087" "unprognostic (3.14e-1)" "unprognostic (1.55e-1)" "unprognostic (9.75e-2)" "unprognostic (5.88e-2)" IFNA10 IFN-alphaC ENSG00000186803 "Interferon alpha 10" P01566 9 21206181-21207143 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "HPA047557: AB_2680087" IFNA13 ENSG00000233816 "Interferon alpha 13" P01562 9 21367372-21368057 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" 1 "HPA047557: AB_2680087" IFNA14 "IFN-alphaH, LEIF2H" ENSG00000228083 "Interferon alpha 14" P01570 9 21239002-21240005 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 58: Macrophages - Innate immune response" "HPA047557: AB_2680087" IFNA16 IFN-alphaO ENSG00000147885 "Interferon alpha 16" P05015 9 21216373-21217311 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA 1 "HPA047557: AB_2680087" IFNA17 "IFN-alphaI, LEIF2C1" ENSG00000234829 "Interferon alpha 17" P01571 9 21227243-21228222 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "HPA047557: AB_2680087" IFNA2 "IFN-alphaA, IFNA" ENSG00000188379 "Interferon alpha 2" P01563 9 21384255-21385398 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Oligodendrocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA 253000 "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 80: Non-specific - Transcription" 2 "HPA047557: AB_2680087" IFNA21 IFN-alphaI ENSG00000137080 "Interferon alpha 21" P01568 9 21165637-21166660 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "HPA047557: AB_2680087" IFNA4 "IFN-alpha4a, MGC142200" ENSG00000236637 "Interferon alpha 4" P05014 9 21186618-21187587 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "HPA047557: AB_2680087" IFNA5 IFN-alphaG ENSG00000147873 "Interferon alpha 5" P01569 9 21304326-21305313 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA047557: AB_2680087" IFNA6 IFN-alphaK ENSG00000120235 "Interferon alpha 6" P05013 9 21350253-21350956 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "HPA047557: AB_2680087" IFNA7 "IFN-alphaJ, IFNA-J" ENSG00000214042 "Interferon alpha 7" P01567 9 21201469-21202205 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 10: Ciliated cells - Ion channel activity" "HPA047557: AB_2680087" IFNA8 IFN-alphaB ENSG00000120242 "Interferon alpha 8" P32881 9 21409117-21410185 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047557 Uncertain "Secreted to blood" Interferon NA NA "Cluster 37: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" 1 "HPA047557: AB_2680087" IFNAR2 IFNABR ENSG00000159110 "Interferon alpha and beta receptor subunit 2" P48551 21 33205282-33265675 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 86.2;Plasma cells: 86.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 108.5" "Colon - Endothelial cells, Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Receptor NA NA 1500000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 7 "unprognostic (2.00e-2)" "unprognostic (7.83e-3)" "unprognostic (4.98e-2)" "unprognostic (1.22e-2)" "unprognostic (1.09e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-3)" "unprognostic (8.05e-2)" "unprognostic (4.17e-2)" "unprognostic (2.11e-2)" "unprognostic (7.65e-2)" "unprognostic (4.42e-1)" "prognostic unfavorable (7.54e-7)" "unprognostic (9.70e-3)" "unprognostic (2.39e-1)" "unprognostic (5.12e-3)" "unprognostic (1.85e-2)" IFNB1 "IFB, IFF, IFNB" ENSG00000171855 "Interferon beta 1" P01574 9 21077104-21077942 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "Hofbauer cells: 7.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073843 Supported "Secreted to blood" Interferon NA NA 3750 "Cluster 53: Neurons - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA073843: " "unprognostic (2.38e-1)" "unprognostic (2.60e-4)" IFNE IFNE1 ENSG00000184995 "Interferon epsilon" Q86WN2 9 21480839-21482313 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 1.4" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 3.6;Cholangiocytes: 1.9;Club cells: 1.3;Gastric mucus-secreting cells: 1.2;Glandular and luminal cells: 1.1;Ionocytes: 2.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Interferon NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 35: Respiratory epithelial cells - Unknown function" "unprognostic (1.52e-3)" "unprognostic (8.36e-2)" "unprognostic (5.44e-2)" "unprognostic (1.56e-5)" "unprognostic (2.70e-1)" "unprognostic (2.25e-1)" "unprognostic (5.14e-3)" "unprognostic (6.32e-1)" "unprognostic (2.68e-2)" "unprognostic (1.14e-2)" "unprognostic (1.43e-2)" "unprognostic (9.63e-3)" "unprognostic (1.04e-1)" "unprognostic (3.27e-2)" "unprognostic (6.58e-3)" "unprognostic (3.34e-2)" IFNG ENSG00000111537 "Interferon gamma" P01579 12 68154768-68159740 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Antiviral defense, Growth regulation" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.4;lymphoid tissue: 7.3" "Group enriched" "Detected in many" 15 "NK-cells: 81.0;T-cells: 211.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "gdT-cell: 5.5;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.6;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 7 "T-cells: 6.6" "Not detected" "Not detected" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB010344 Approved "Secreted to blood" Interferon NA NA "Cluster 24: Non-specific - Transcription" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" 1 "CAB010344: AB_2123447" "unprognostic (2.16e-4)" "unprognostic (1.93e-3)" "unprognostic (9.21e-2)" "unprognostic (1.04e-4)" "unprognostic (5.14e-1)" "unprognostic (3.96e-3)" "unprognostic (1.33e-1)" "unprognostic (3.17e-4)" "unprognostic (7.79e-2)" "unprognostic (7.97e-3)" "unprognostic (1.63e-2)" "unprognostic (5.36e-2)" "unprognostic (7.62e-9)" "unprognostic (3.54e-2)" "unprognostic (5.36e-1)" "unprognostic (6.32e-2)" "unprognostic (7.38e-3)" IFNK ENSG00000147896 "Interferon kappa" Q9P0W0 9 27524290-27526498 "Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 0.5;head and neck cancer: 0.6;urothelial cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 35 "Bladder cancer: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Interferon NA NA "Cluster 11: White matter - Signal transduction" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Non-specific - Mixed function" "unprognostic (5.58e-3)" "unprognostic (4.64e-3)" "unprognostic (1.06e-1)" IFNL1 "IL-29, IL29" ENSG00000182393 "Interferon lambda 1" Q8IU54 19 39296407-39298673 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Langerhans cells: 10.1;NK-cells: 9.0;T-cells: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 10 "gdT-cell: 2.7;MAIT T-cell: 2.8;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.7;myeloid DC: 2.3;naive CD8 T-cell: 1.4;NK-cell: 4.6" "Group enriched" "Detected in many" 33 "dendritic cells: 2.3;NK-cells: 4.6;T-cells: 2.8" "Not detected" "Not detected" "Secreted to blood" Interferon NA NA 97000 "Cluster 1: T-cells - Unknown function" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" "unprognostic (3.08e-2)" "unprognostic (8.74e-2)" "unprognostic (2.46e-4)" "unprognostic (5.76e-2)" "unprognostic (6.91e-3)" "unprognostic (5.73e-3)" "unprognostic (3.94e-2)" "unprognostic (4.80e-2)" "unprognostic (2.96e-5)" "unprognostic (7.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" IFNL2 "IL-28A, IL28A" ENSG00000183709 "Interferon lambda 2" Q8IZJ0 19 39268396-39270188 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 14 "Breast myoepithelial cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB025489 Uncertain "Secreted to blood" Interferon NA NA "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 17: Breast glandular cells - Lactation" "CAB025489: " "unprognostic (1.37e-1)" "unprognostic (2.84e-1)" "unprognostic (1.05e-1)" "unprognostic (2.11e-2)" "unprognostic (1.08e-1)" "unprognostic (6.96e-2)" IFNL3 "IL-28B, IL28B, IL28C" ENSG00000197110 "Interferon lambda 3" Q8IZI9 19 39243455-39245250 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 11 "Breast myoepithelial cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interferon NA NA 1700 "Cluster 31: Non-specific - Antiviral immune response" "Cluster 21: Early spermatids - Spermatogenesis" "unprognostic (2.67e-1)" "unprognostic (9.19e-2)" "unprognostic (4.17e-1)" "unprognostic (6.86e-2)" "unprognostic (1.89e-2)" "unprognostic (1.66e-1)" IFNL4 IFNAN ENSG00000272395 "Interferon lambda 4 (gene/pseudogene)" 19 39246314-39248856 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Late spermatids: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 21: Early spermatids - Spermatogenesis" "unprognostic (1.84e-1)" "unprognostic (6.09e-3)" "unprognostic (3.76e-1)" "unprognostic (2.60e-2)" IFNLR1 "CRF2/12, IFNLR, IL-28R1, IL28RA" ENSG00000185436 "Interferon lambda receptor 1" Q8IU57 1 24154168-24187959 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 13.3;dendritic cells: 14.7;Proximal enterocytes: 16.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 4.9;naive B-cell: 5.9;plasmacytoid DC: 11.4" "Group enriched" "Detected in many" 5 "B-cells: 5.9;dendritic cells: 11.4" "Cancer enhanced" "Detected in many" "lymphoma: 20.0" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017319 Uncertain Approved Cytosol "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" 2 Cytosol "HPA017319: AB_1851708" "prognostic favorable (5.12e-4)" "unprognostic (7.16e-2)" "unprognostic (8.61e-3)" "unprognostic (8.48e-2)" "unprognostic (8.09e-2)" "unprognostic (1.22e-2)" "unprognostic (7.28e-3)" "unprognostic (2.33e-1)" "unprognostic (5.10e-2)" "unprognostic (1.93e-1)" "unprognostic (5.51e-2)" "unprognostic (4.50e-1)" "unprognostic (3.66e-3)" "unprognostic (5.15e-2)" "unprognostic (1.69e-1)" "unprognostic (2.69e-1)" "unprognostic (1.10e-1)" IFNW1 ENSG00000177047 "Interferon omega 1" P05000 9 21140632-21141832 "Predicted secreted proteins" "Antiviral defense" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interferon NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" IGF1 "IGF, IGF-I, IGF1A, IGFI" ENSG00000017427 "Insulin like growth factor 1" P05019 12 102395874-102481744 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 85.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1287.0;Fibroblasts: 441.6;Hepatocytes: 238.1;Leydig cells: 1105.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.4" "Lineage enriched" "Detected in single" 24 "B-cells: 2.4" "Group enriched" "Detected in many" 5 "Bone cancer: 7.3;Myeloma: 22.2" "Breast - Adipocytes (Breast), Colon - Endothelial cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048946 Approved "Secreted to blood" "Growth factor" NA NA 103000000 330000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 62: Connective tissue - ECM organization" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: Endometrial stromal cells - Transcription" 3 "HPA048946: AB_2680566" "unprognostic (1.25e-1)" "unprognostic (2.86e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.04e-4)" "unprognostic (1.52e-1)" "unprognostic (2.10e-1)" "unprognostic (1.59e-3)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.04e-2)" "unprognostic (2.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-3)" IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2158391 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "placenta: 2670.3" "Cell type enhanced" "Detected in some" "Adipocytes: 75.8;Cytotrophoblasts: 117.3;Extravillous trophoblasts: 251.5;Leydig cells: 162.0;Syncytiotrophoblasts: 175.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 618.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 597.2;Sarcoma: 625.3" "Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007556 Enhanced Approved "Golgi apparatus" "Secreted to blood" Hormone NA NA 609000000 1200000000 "Cluster 58: Placenta - Pregnancy" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 4: Extravillous trophoblasts - Unknown function" 2 "Golgi apparatus" "HPA007556: AB_2667860" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" IGFALS ALS ENSG00000099769 "Insulin like growth factor binding protein acid labile subunit" P35858 16 1790413-1794971 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 113.8" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 65.5" "Cancer enhanced" "Detected in many" "liver cancer: 11.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040692, HPA040948" Supported "Secreted to blood" "Cell adhesion" NA NA 14700000000 26000000000 "Cluster 83: Liver - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Hepatocytes - Metabolism" "HPA040692: AB_10794067, HPA040948: AB_10794999" "unprognostic (2.74e-3)" "unprognostic (1.95e-1)" "unprognostic (9.13e-2)" "prognostic unfavorable (6.06e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-2)" "prognostic favorable (5.97e-4)" "unprognostic (5.54e-4)" "unprognostic (3.00e-1)" "unprognostic (1.17e-1)" "unprognostic (9.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (4.39e-1)" "unprognostic (5.51e-2)" IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1163.6" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 900.0" "Cancer enriched" "Detected in many" 29 "liver cancer: 385.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 38.2;liver cancer: 75.4;ovarian cancer: 50.4" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" Other NA NA 28100000 25000000 "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Hepatocytes - Metabolism" 3 "Golgi apparatus" "CAB004445: AB_627782, HPA046972: AB_2679884, HPA050640: AB_2681197" "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (9.41e-2)" "unprognostic (7.80e-2)" "unprognostic (7.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.90e-11)" "prognostic unfavorable (6.64e-4)" "unprognostic (7.20e-2)" "unprognostic (7.98e-2)" "unprognostic (3.43e-1)" IGFBP2 IBP2 ENSG00000115457 "Insulin like growth factor binding protein 2" P18065 2 216632828-216664436 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 926.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 656.1;Endometrial stromal cells: 1446.9;Granulosa cells: 948.5;Hepatocytes: 527.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 8 "choroid plexus: 238.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pancreas - Exocrine glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077723 Approved "Endoplasmic reticulum" "Secreted to blood" Other NA NA 303000000 810000000 "Cluster 68: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 9: Endometrial stromal cells - Transcription" 1 "Endoplasmic reticulum" "HPA077723: AB_2686853" "unprognostic (2.58e-1)" "unprognostic (5.95e-2)" "unprognostic (1.94e-1)" "unprognostic (3.32e-3)" "unprognostic (9.50e-3)" "unprognostic (2.36e-2)" "unprognostic (2.06e-1)" "unprognostic (9.11e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.22e-5)" "unprognostic (5.04e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.22e-1)" IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 693.4;placenta: 1799.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 815.8;Club cells: 408.7;Extravillous trophoblasts: 2449.9;Ionocytes: 425.9" "Cancer enhanced" "Detected in all" "renal cancer: 377.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 48.9" "Lineage enriched" "Detected in many" 5 "dendritic cells: 48.9" "Cancer enriched" "Detected in all" 5 "Kidney cancer: 3358.0" "Liver - Hepatic stellate cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB010360 Uncertain Vesicles "Secreted to blood" Other NA NA 3250000000 3600000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 5 Vesicles "CAB010360: AB_2233528" "unprognostic (4.46e-3)" "unprognostic (4.84e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (8.14e-3)" "unprognostic (3.31e-2)" "unprognostic (2.03e-1)" "unprognostic (9.67e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (5.07e-7)" "unprognostic (2.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-3)" "unprognostic (2.63e-1)" IGFBP4 "BP-4, HT29-IGFBP, IBP4, IGFBP-4" ENSG00000141753 "Insulin like growth factor binding protein 4" P22692 17 40443450-40457725 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 646.9;Endometrial stromal cells: 547.6;Endothelial cells: 579.4;Fibroblasts: 719.0;Hepatocytes: 406.4;Lymphatic endothelial cells: 414.7;Mesothelial cells: 410.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 19.6;NK-cell: 37.1" "Group enriched" "Detected in many" 5 "NK-cells: 37.1;T-cells: 19.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066240 Supported "Secreted to blood" Other NA NA 227000000 410000000 "Cluster 15: NK-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 10 "HPA066240: AB_2685643" "unprognostic (1.03e-3)" "unprognostic (1.61e-1)" "unprognostic (1.85e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.44e-3)" "unprognostic (1.00e-1)" "prognostic favorable (5.49e-4)" "unprognostic (4.55e-2)" "unprognostic (1.19e-2)" "unprognostic (2.28e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (6.23e-2)" "unprognostic (1.73e-1)" "unprognostic (2.36e-1)" "unprognostic (3.81e-2)" IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1439.2;ovary: 1232.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 1641.6;Granulosa cells: 1338.6;Leydig cells: 1791.9;Ovarian stromal cells: 2540.9;Peritubular cells: 982.9;Smooth muscle cells: 1479.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 337.9;breast cancer: 378.2" "Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040514, HPA070407" Supported Approved Vesicles "Secreted to blood" Other NA NA 110000000 380000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 6: Ovarian stromal cells - Transcription" 63 Vesicles "HPA040514: AB_2677016, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" IGFBP6 ENSG00000167779 "Insulin like growth factor binding protein 6" P24592 12 53097436-53102345 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 348.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 530.2;Fibroblasts: 1573.6;Leydig cells: 978.1;Peritubular cells: 1530.1;Sertoli cells: 492.3;Smooth muscle cells: 600.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 145.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 31.7;non-classical monocyte: 20.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 139.2" "HPA008005, HPA075088" Uncertain "Secreted to blood" Other NA NA 199000000 300000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 28 "HPA008005: AB_1851499, HPA075088: " "unprognostic (4.93e-3)" "unprognostic (2.61e-1)" "unprognostic (2.55e-1)" "unprognostic (8.62e-2)" "prognostic unfavorable (4.80e-4)" "unprognostic (2.55e-1)" "unprognostic (9.79e-2)" "unprognostic (2.00e-2)" "unprognostic (2.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.52e-2)" "unprognostic (4.05e-2)" "unprognostic (1.23e-3)" "unprognostic (6.97e-3)" "unprognostic (1.22e-1)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" IGFBP7 "FSTL2, IGFBP-7, MAC25, PSF" ENSG00000163453 "Insulin like growth factor binding protein 7" Q16270 4 57030773-57110385 "Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 11372.7;Lymphatic endothelial cells: 4268.3;Peritubular cells: 11790.1;Sertoli cells: 3560.1;Smooth muscle cells: 4123.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 8 "choroid plexus: 2654.6" "Immune cell enhanced" "Detected in many" "eosinophil: 21.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 739.6;Kidney cancer: 772.0" "Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002196, CAB020668" Approved Approved "Golgi apparatus" "Secreted to blood" "Cell adhesion" NA NA 30300000 190000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "Golgi apparatus" "CAB020668: , HPA002196: AB_1079107" "unprognostic (2.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.82e-2)" "unprognostic (5.97e-3)" "unprognostic (3.86e-1)" "unprognostic (3.18e-1)" "unprognostic (2.96e-3)" "unprognostic (1.02e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-2)" "unprognostic (2.57e-1)" "unprognostic (6.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-3)" "unprognostic (1.78e-1)" "unprognostic (3.58e-1)" "unprognostic (7.55e-2)" IGFBPL1 bA113O24.1 ENSG00000137142 "Insulin like growth factor binding protein like 1" Q8WX77 9 38406528-38424454 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "thyroid gland: 16.0" "Cell type enhanced" "Detected in some" "Early spermatids: 13.8;Enteroendocrine cells: 7.5;Hofbauer cells: 5.9;Late spermatids: 25.3;Oocytes: 8.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Neuroblastoma: 122.0;testis cancer: 222.3" "Adipose subcutaneous - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051354 Uncertain Uncertain Nucleoplasm,Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 10: Muller glia cells - Visual perception" "Nucleoplasm, Vesicles" "HPA051354: " "unprognostic (5.63e-2)" "unprognostic (3.33e-1)" "unprognostic (5.22e-2)" "unprognostic (2.42e-1)" "unprognostic (2.56e-2)" "unprognostic (1.92e-1)" "unprognostic (1.30e-1)" "unprognostic (5.66e-2)" "unprognostic (2.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (3.94e-1)" "unprognostic (3.92e-2)" "unprognostic (1.59e-2)" "unprognostic (6.67e-2)" IGFL1 UNQ644 ENSG00000188293 "IGF like family member 1" Q6UW32 19 46229742-46231243 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 109.8;salivary gland: 33.5;vagina: 30.6" "Cell type enriched" "Detected in some" 41 "Suprabasal keratinocytes: 451.2" "Group enriched" "Detected in many" 7 "cervical cancer: 47.6;head and neck cancer: 60.7;melanoma: 23.3;urothelial cancer: 84.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 30.2;head and neck cancer: 34.3" HPA014001 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 2 "HPA014001: AB_2668919" "unprognostic (1.35e-1)" "unprognostic (9.70e-2)" "unprognostic (2.89e-1)" "unprognostic (1.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.67e-2)" "unprognostic (3.06e-1)" "unprognostic (4.50e-3)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (3.23e-1)" IGFL2 UNQ645 ENSG00000204866 "IGF like family member 2" Q6UWQ7 19 46143106-46161298 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 40.3" "Cell type enhanced" "Detected in some" "Astrocytes: 17.0;Excitatory neurons: 26.1;Inhibitory neurons: 28.1;Oligodendrocytes: 35.8;Suprabasal keratinocytes: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 102.4" "Adipose visceral - Mesothelial cells, Testis - Early spermatids" HPA059137 Uncertain Approved "Nucleoplasm,Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA "Cluster 13: Skin - Cornification" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" Nucleoplasm "Plasma membrane" "HPA059137: AB_2683920" "unprognostic (1.53e-1)" "unprognostic (7.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.69e-2)" "unprognostic (7.30e-2)" "unprognostic (9.74e-2)" "unprognostic (1.92e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (1.68e-1)" "unprognostic (4.26e-3)" "unprognostic (9.63e-3)" "unprognostic (4.14e-9)" "unprognostic (1.27e-1)" "unprognostic (2.76e-2)" "unprognostic (8.73e-2)" "unprognostic (9.91e-3)" IGFL3 UNQ483 ENSG00000188624 "IGF like family member 3" Q6UXB1 19 46120067-46124688 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 26.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.2;Basal respiratory cells: 1.5;Exocrine glandular cells: 2.4;Late spermatids: 1.1;Suprabasal keratinocytes: 4.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Rhabdoid: 213.3" HPA062776 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 82: Skin - Keratinization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA062776: AB_2684866" "unprognostic (8.61e-2)" "unprognostic (6.26e-2)" "unprognostic (2.69e-1)" "unprognostic (4.78e-2)" "unprognostic (7.45e-3)" "unprognostic (2.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.90e-1)" "unprognostic (1.86e-4)" "unprognostic (2.86e-2)" "unprognostic (1.90e-1)" "unprognostic (3.69e-2)" IGFL4 ENSG00000204869 "IGF like family member 4" Q6B9Z1 19 46039182-46077118 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "retina: 48.5;skin 1: 12.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.1;Cone photoreceptor cells: 10.2;Excitatory neurons: 9.2;Inhibitory neurons: 9.6;Rod photoreceptor cells: 39.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA047655 Approved Approved Cytosol "Secreted - unknown location" "No annotated function" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 76: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" Cytosol "HPA047655: AB_2680113" "unprognostic (1.22e-2)" "unprognostic (3.37e-2)" "unprognostic (2.57e-1)" "unprognostic (7.96e-2)" "unprognostic (5.48e-2)" "unprognostic (1.03e-1)" "unprognostic (2.39e-1)" "unprognostic (8.25e-2)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (1.09e-2)" "unprognostic (3.59e-4)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (3.38e-1)" "unprognostic (2.85e-1)" IGFLR1 "FLJ22573, TMEM149, U2AF1L4" ENSG00000126246 "IGF like family receptor 1" Q9H665 19 35738801-35742453 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 48.7" "Cell type enhanced" "Detected in many" "B-cells: 20.3;dendritic cells: 42.6;Hepatocytes: 21.0;Langerhans cells: 44.5;Macrophages: 21.5;Plasma cells: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 901.7" "Lineage enriched" "Detected in all" 4 "dendritic cells: 901.7" "Cancer enhanced" "Detected in all" "Myeloma: 17.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA012369, HPA070778" Uncertain Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 47: Spleen - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 1 "Nucleoplasm, Plasma membrane" "HPA012369: AB_1858095, HPA070778: " "unprognostic (5.97e-3)" "prognostic favorable (6.55e-4)" "unprognostic (1.94e-1)" "unprognostic (5.42e-2)" "unprognostic (8.31e-3)" "unprognostic (2.34e-4)" "unprognostic (6.71e-2)" "unprognostic (1.74e-2)" "unprognostic (1.87e-2)" "prognostic favorable (1.59e-5)" "unprognostic (1.44e-3)" "unprognostic (3.52e-1)" "unprognostic (8.72e-12)" "unprognostic (2.74e-1)" "unprognostic (1.22e-1)" "unprognostic (2.29e-1)" "unprognostic (3.32e-3)" IGHA1 AL928768.3 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7198.9;salivary gland: 4545.3;stomach 1: 6480.0" "Cell type enriched" "Detected in many" 16 "Plasma cells: 107776.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2579.2;naive B-cell: 1123.4" "Lineage enriched" "Detected in many" 282 "B-cells: 2579.2" "Cancer enriched" "Detected in some" 20 "Myeloma: 1517.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "HPA001217, HPA006013" Approved "Immunoglobulin genes" Immunity NA NA 130000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (8.87e-5)" "unprognostic (5.36e-3)" "unprognostic (2.10e-2)" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "prognostic favorable (3.81e-5)" "unprognostic (1.17e-1)" "unprognostic (3.86e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.83e-7)" "unprognostic (8.10e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "intestine: 562.7" "Cell type enriched" "Detected in many" 30 "Plasma cells: 9424.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 878 "memory B-cell: 280.4;naive B-cell: 124.8" "Lineage enriched" "Detected in single" 1215 "B-cells: 280.4" "Cancer enriched" "Detected in some" 5 "Myeloma: 47.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "HPA001217, HPA006013" Approved "Immunoglobulin genes" Immunity NA NA 67000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (1.98e-9)" "unprognostic (3.20e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.40e-5)" "unprognostic (4.56e-2)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (3.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.50e-6)" "unprognostic (2.12e-1)" "unprognostic (3.28e-2)" "unprognostic (9.70e-2)" "unprognostic (4.47e-1)" IGHD1-1 IGHD11 ENSG00000236170 "Immunoglobulin heavy diversity 1-1" P0DOY5 14 105919502-105919518 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA IGHE ENSG00000211891 "Immunoglobulin heavy constant epsilon" P01854 14 105597691-105601728 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "B-cells: 96.6;Oocytes: 157.3;Plasma cells: 42.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 29 "Myeloma: 138.8" "Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA 77000000 "Cluster 20: Myeloma - Immune response" "Cluster 73: B-cells - B-cell function" "unprognostic (3.18e-2)" "unprognostic (1.28e-2)" "unprognostic (1.54e-3)" "unprognostic (4.99e-1)" "unprognostic (4.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (2.40e-2)" "unprognostic (8.04e-2)" "unprognostic (3.88e-2)" "unprognostic (3.01e-3)" "unprognostic (1.07e-2)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.63e-1)" IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 5665.1;urinary bladder: 3867.4" "Cell type enriched" "Detected in many" 5 "Plasma cells: 12047.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 768.6" "Lineage enriched" "Detected in many" 122 "B-cells: 768.6" "Cancer enriched" "Detected in some" 8 "Myeloma: 1184.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "HPA001245, CAB008642" Supported "Immunoglobulin genes" Immunity NA NA 230000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 1 "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 189.5;urinary bladder: 108.3" "Cell type enriched" "Detected in some" 11 "Plasma cells: 4935.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 460 "memory B-cell: 344.6;naive B-cell: 128.5" "Lineage enriched" "Detected in single" 670 "B-cells: 344.6" "Group enriched" "Detected in some" 9 "lymphoma: 19.2;Myeloma: 54.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA001245 Approved "Immunoglobulin genes" Immunity NA NA 250000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA001245: AB_1079121" "prognostic favorable (3.53e-4)" "unprognostic (6.88e-3)" "unprognostic (2.40e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "prognostic favorable (3.30e-6)" "unprognostic (1.06e-1)" "unprognostic (6.67e-2)" "unprognostic (1.74e-1)" "unprognostic (7.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (4.72e-2)" "unprognostic (3.32e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-2)" IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 904.5" "Cell type enriched" "Detected in many" 5 "Plasma cells: 5943.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 416 "memory B-cell: 211.7;naive B-cell: 65.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.7" "Cancer enriched" "Detected in some" 4 "lymphoma: 97.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" IGHG4 ENSG00000211892 "Immunoglobulin heavy constant gamma 4 (G4m marker)" P01861 14 105620506-105626066 "FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 2402.4" "Group enriched" "Detected in some" 4 "B-cells: 423.0;Plasma cells: 595.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 457 "memory B-cell: 123.0;naive B-cell: 74.3" "Lineage enriched" "Detected in single" 569 "B-cells: 123.0" "Group enriched" "Detected in some" 43 "lymphoma: 133.6;Myeloma: 34.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Mesothelial cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells" HPA001245 Approved "Immunoglobulin genes" Immunity NA NA 170000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "HPA001245: AB_1079121" "unprognostic (7.29e-3)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.16e-4)" "unprognostic (4.58e-1)" "unprognostic (1.92e-2)" "unprognostic (3.49e-1)" "unprognostic (8.63e-2)" "unprognostic (4.74e-2)" "unprognostic (6.71e-2)" "prognostic unfavorable (9.09e-8)" "unprognostic (2.84e-2)" "unprognostic (4.23e-1)" "unprognostic (9.24e-2)" "unprognostic (7.72e-2)" IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 355.2;lymphoid tissue: 408.4;salivary gland: 113.8;stomach 1: 253.6" "Cell type enriched" "Detected in single" 19 "Plasma cells: 1.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 3.6" "Group enriched" "Detected in some" 72 "memory B-cell: 277.0;naive B-cell: 181.7;plasmacytoid DC: 99.3" "Group enriched" "Detected in many" 73 "B-cells: 277.0;dendritic cells: 99.3" "Group enriched" "Detected in some" 6 "Leukemia: 3.4;lymphoma: 2.4;Myeloma: 1.5" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (5.28e-3)" "unprognostic (2.05e-2)" "unprognostic (6.81e-2)" "unprognostic (9.53e-2)" "prognostic favorable (3.55e-4)" "unprognostic (2.51e-1)" "unprognostic (2.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" IGHM ENSG00000211899 "Immunoglobulin heavy constant mu" P01871 14 105851705-105856218 "Disease related genes, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 1279.4;lymphoid tissue: 3116.6" "Group enriched" "Detected in some" 8 "B-cells: 2732.6;Plasma cells: 9466.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 16 "memory B-cell: 4293.6;naive B-cell: 6750.1" "Lineage enriched" "Detected in all" 19 "B-cells: 6750.1" "Cancer enriched" "Detected in some" 4 "lymphoma: 1665.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008643 Uncertain "Immunoglobulin genes" Immunity NA NA 110000000000 "Cluster 18: Non-specific - Translation" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "CAB008643: AB_1617732" "unprognostic (2.91e-3)" "prognostic favorable (6.49e-4)" "unprognostic (9.30e-3)" "unprognostic (9.90e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.70e-6)" "unprognostic (9.61e-3)" "unprognostic (1.01e-1)" "unprognostic (1.52e-2)" "unprognostic (3.23e-3)" "unprognostic (2.46e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (3.01e-1)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (6.28e-3)" IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 12 "esophagus: 155.7;urinary bladder: 150.1" "Cell type enriched" "Detected in some" 21 "Plasma cells: 8841.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.4" "Lineage enriched" "Detected in many" 21 "B-cells: 73.4" "Cancer enriched" "Detected in single" 121 "lymphoma: 41.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 4700000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 445.0;lymphoid tissue: 1121.8" "Cell type enriched" "Detected in some" 42 "Plasma cells: 849.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 51 "memory B-cell: 286.5;naive B-cell: 348.4" "Lineage enriched" "Detected in many" 56 "B-cells: 348.4" "Cancer enriched" "Detected in some" 8 "Myeloma: 578.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 4000000000 "Cluster 18: Non-specific - Translation" "Cluster 8: Immune cells - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (1.63e-3)" "unprognostic (1.09e-3)" "unprognostic (1.88e-1)" "unprognostic (9.46e-2)" "unprognostic (5.78e-2)" "prognostic favorable (1.67e-5)" "unprognostic (9.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.99e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.17e-2)" "unprognostic (8.59e-2)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" IGHV1-24 ENSG00000211950 "Immunoglobulin heavy variable 1-24" A0A0C4DH33 14 106276548-106277043 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 54.0;esophagus: 44.6;lymphoid tissue: 33.0;urinary bladder: 62.1" "Cell type enriched" "Detected in some" 19 "Plasma cells: 974.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.3;medulla oblongata: 2.7" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.8" "Lineage enriched" "Detected in single" 9 "B-cells: 2.8" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.2" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 3100000000 "Cluster 14: Non-specific - Unknown function" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (9.01e-4)" "unprognostic (2.67e-2)" "unprognostic (1.66e-2)" "unprognostic (1.93e-3)" "prognostic favorable (3.61e-4)" "unprognostic (1.28e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.59e-1)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.07e-7)" "unprognostic (5.43e-2)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "unprognostic (4.78e-2)" IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 215.2;lymphoid tissue: 608.8" "Cell type enriched" "Detected in some" 197 "Plasma cells: 7201.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 7 "memory B-cell: 52.9;naive B-cell: 27.9" "Lineage enriched" "Detected in many" 9 "B-cells: 52.9" "Cancer enriched" "Detected in some" 30 "Myeloma: 733.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 2600000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" IGHV1-45 ENSG00000211961 "Immunoglobulin heavy variable 1-45" A0A0A0MS14 14 106506996-106507491 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 18.2;lymphoid tissue: 29.3;stomach 1: 16.9" "Cell type enriched" "Detected in single" 13 "Plasma cells: 3.6" "Cancer enriched" "Detected in many" 7 "lung cancer: 15.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.1" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 380000000 "Cluster 24: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (5.57e-4)" "unprognostic (5.07e-3)" "unprognostic (2.12e-3)" "unprognostic (1.46e-1)" "unprognostic (7.64e-3)" "unprognostic (2.90e-1)" "unprognostic (3.50e-2)" "unprognostic (3.16e-1)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.05e-1)" "unprognostic (1.28e-3)" "unprognostic (2.94e-2)" "unprognostic (2.87e-1)" "unprognostic (2.32e-1)" "unprognostic (3.16e-1)" IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 43.3;lung: 11.1;salivary gland: 20.2" "Cell type enriched" "Detected in some" 27 "Plasma cells: 7343.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "Myeloma: 18.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 2900000000 "Cluster 55: Lymphoma - Immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" IGHV1-58 ENSG00000211968 "Immunoglobulin heavy variable 1-58" A0A0C4DH39 14 106622357-106622855 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 49.5;urinary bladder: 197.8" "Cell type enriched" "Detected in some" 36 "Plasma cells: 82.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 49 "memory B-cell: 8.7;naive B-cell: 12.8" "Lineage enriched" "Detected in single" 58 "B-cells: 12.8" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 120000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 6: Leukemia - Signal transduction" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (9.63e-3)" "unprognostic (6.78e-2)" "unprognostic (5.64e-2)" "unprognostic (4.04e-2)" "prognostic favorable (7.25e-4)" "unprognostic (4.56e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-1)" "unprognostic (1.46e-2)" "unprognostic (4.89e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (3.24e-2)" "unprognostic (5.28e-2)" "unprognostic (6.79e-2)" "unprognostic (1.36e-1)" IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "gallbladder: 73.2;intestine: 133.8;urinary bladder: 160.6" "Cell type enriched" "Detected in some" 134 "Plasma cells: 198.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 18 "medulla oblongata: 4.9;pons: 5.9" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 9 "lymphoma: 2.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 2700000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (3.51e-3)" "unprognostic (7.03e-2)" "prognostic favorable (9.56e-5)" "prognostic favorable (8.32e-4)" "unprognostic (1.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (8.20e-2)" "unprognostic (6.82e-2)" IGHV1-69-2 IGHV1-F ENSG00000281990 "Immunoglobulin heavy variable 1-69-2" A0A0G2JMI3 14 106737110-106737547 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 14.0;intestine: 21.4;lymphoid tissue: 35.4;salivary gland: 15.8;stomach 1: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 6.7;naive B-cell: 5.5" "Lineage enriched" "Detected in many" 6 "B-cells: 6.7" "Cancer enhanced" "Detected in single" "Leukemia: 1.4" "Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 1100000000 "Cluster 34: B-cells - Unknown function" "Cluster 6: Leukemia - Signal transduction" "Cluster 61: Plasma cells - Immunoglobulins & histones" IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2804.1;stomach 1: 960.1" "Cell type enriched" "Detected in some" 167 "Plasma cells: 6373.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 225 "memory B-cell: 185.4;naive B-cell: 435.3" "Lineage enriched" "Detected in many" 316 "B-cells: 435.3" "Cancer enriched" "Detected in some" 8 "lymphoma: 278.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 1200000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" IGHV2-26 ENSG00000211951 "Immunoglobulin heavy variable 2-26" A0A0B4J1V2 14 106301396-106301862 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 124.0;urinary bladder: 221.0" "Cell type enriched" "Detected in some" 14 "Plasma cells: 107.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 14 "memory B-cell: 14.1" "Lineage enriched" "Detected in single" 141 "B-cells: 14.1" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 190000000 "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (9.39e-3)" "unprognostic (4.50e-2)" "unprognostic (7.66e-3)" "unprognostic (2.94e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-2)" "unprognostic (1.18e-1)" "unprognostic (1.67e-1)" "unprognostic (1.72e-1)" "unprognostic (2.13e-2)" "unprognostic (4.99e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (6.68e-2)" "unprognostic (2.61e-1)" "unprognostic (2.24e-1)" "unprognostic (8.09e-2)" IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 448.7;lymphoid tissue: 1381.5;stomach 1: 686.9" "Cell type enriched" "Detected in some" 199 "Plasma cells: 6554.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 22 "memory B-cell: 67.0;naive B-cell: 67.6" "Lineage enriched" "Detected in many" 22 "B-cells: 67.6" "Cancer enriched" "Detected in some" 32 "Myeloma: 1988.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 700000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" IGHV2-70 ENSG00000274576 "Immunoglobulin heavy variable 2-70" P01814 14 106770577-106771020 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 704.3;stomach 1: 487.4" "Cell type enriched" "Detected in some" 507 "Plasma cells: 5448.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 8.4" "Group enriched" "Detected in some" 242 "memory B-cell: 24.7;naive B-cell: 23.5" "Lineage enriched" "Detected in single" 248 "B-cells: 24.7" "Cancer enriched" "Detected in some" 5 "lymphoma: 124.6" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 170000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "unprognostic (8.01e-3)" "unprognostic (2.93e-2)" "unprognostic (3.56e-3)" "unprognostic (2.38e-2)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (9.10e-2)" "unprognostic (2.50e-1)" "unprognostic (8.93e-2)" "unprognostic (2.91e-1)" IGHV2-70D ENSG00000211974 "Immunoglobulin heavy variable 2-70D" A0A0C4DH43 14 106723574-106724093 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.5;lymphoid tissue: 88.5;stomach 1: 45.6" "Cell type enriched" "Detected in single" 116 "Plasma cells: 39.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 68 "memory B-cell: 9.7;naive B-cell: 3.8" "Lineage enriched" "Detected in single" 98 "B-cells: 9.7" "Cancer enriched" "Detected in single" 5 "lymphoma: 2.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 110000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "unprognostic (5.57e-2)" "unprognostic (9.48e-3)" "prognostic favorable (3.34e-4)" "unprognostic (4.34e-2)" "unprognostic (8.37e-3)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.13e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.70e-2)" "unprognostic (3.83e-1)" "unprognostic (3.66e-2)" "unprognostic (8.11e-2)" IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 212.3;lymphoid tissue: 594.5;stomach 1: 200.6" "Cell type enriched" "Detected in some" 66 "Plasma cells: 1519.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 446 "memory B-cell: 43.2;naive B-cell: 45.9" "Lineage enriched" "Detected in single" 459 "B-cells: 45.9" "Cancer enriched" "Detected in some" 14 "lymphoma: 17.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 18000000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" IGHV3-13 ENSG00000211942 "Immunoglobulin heavy variable 3-13" P01766 14 106129540-106130072 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 65.0;lymphoid tissue: 133.1;urinary bladder: 87.5" "Cell type enriched" "Detected in some" 19 "Plasma cells: 84.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 194 "memory B-cell: 18.9;naive B-cell: 19.7" "Lineage enriched" "Detected in single" 197 "B-cells: 19.7" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 33000000000 "Cluster 14: Non-specific - Unknown function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (3.24e-4)" "unprognostic (7.42e-2)" "unprognostic (1.96e-2)" "unprognostic (5.03e-2)" "prognostic favorable (6.67e-6)" "unprognostic (5.44e-2)" "unprognostic (1.23e-2)" "unprognostic (1.53e-1)" "unprognostic (5.31e-2)" "unprognostic (8.27e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (7.21e-5)" "unprognostic (6.79e-2)" "unprognostic (3.21e-1)" "unprognostic (4.45e-1)" "unprognostic (7.87e-2)" IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 186.7;stomach 1: 112.7;urinary bladder: 171.3" "Cell type enriched" "Detected in some" 149 "Plasma cells: 5188.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.7;memory B-cell: 26.1" "Group enriched" "Detected in many" 9 "B-cells: 26.1;T-cells: 21.7" "Group enriched" "Detected in some" 65 "Leukemia: 13.6;lymphoma: 27.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 20000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 43: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" IGHV3-16 ENSG00000211944 "Immunoglobulin heavy variable 3-16 (non-functional)" A0A0C4DH30 14 106165205-106165730 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 20 "Plasma cells: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 3200000000 "Cluster 59: Leukemia - T-cell receptor" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 96.3;lymphoid tissue: 210.0;stomach 1: 118.9;urinary bladder: 79.2" "Cell type enriched" "Detected in some" 147 "Plasma cells: 605.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 243 "memory B-cell: 28.6;naive B-cell: 19.9" "Lineage enriched" "Detected in single" 287 "B-cells: 28.6" "Cancer enhanced" "Detected in single" "Leukemia: 1.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 2200000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 35: RS4;11 - Unknown function" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 15.7" "Cell type enriched" "Detected in some" 76 "Plasma cells: 3025.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "white matter: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "lymphoma: 60.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 37000000000 "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1624.0;lymphoid tissue: 2897.8" "Cell type enriched" "Detected in some" 117 "Plasma cells: 10240.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 404 "memory B-cell: 550.6;naive B-cell: 338.3" "Lineage enriched" "Detected in many" 501 "B-cells: 550.6" "Cancer enriched" "Detected in some" 18 "Myeloma: 724.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 42000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 515.2;lymphoid tissue: 1254.8;stomach 1: 555.9" "Cell type enriched" "Detected in some" 131 "Plasma cells: 8897.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 408 "memory B-cell: 164.7;naive B-cell: 137.2" "Lineage enriched" "Detected in single" 445 "B-cells: 164.7" "Cancer enriched" "Detected in some" 7 "Myeloma: 279.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 8500000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1029.4;lymphoid tissue: 2300.1;stomach 1: 1727.2" "Cell type enriched" "Detected in some" 87 "Plasma cells: 1362.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 6.6" "Group enriched" "Detected in many" 101 "memory B-cell: 380.3;naive B-cell: 365.8" "Lineage enriched" "Detected in many" 103 "B-cells: 380.3" "Cancer enriched" "Detected in some" 6 "lymphoma: 24.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 7500000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" IGHV3-35 ENSG00000211957 "Immunoglobulin heavy variable 3-35 (non-functional)" A0A0C4DH35 14 106389392-106389858 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 13.7;lymphoid tissue: 12.4;salivary gland: 7.3;stomach 1: 16.3;urinary bladder: 19.8" "Cell type enriched" "Detected in single" 27 "Plasma cells: 2.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "memory B-cell: 3.7" "Lineage enriched" "Detected in single" 35 "B-cells: 3.7" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 19000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (1.39e-3)" "unprognostic (9.98e-2)" "unprognostic (1.16e-2)" "unprognostic (1.60e-2)" "prognostic favorable (2.53e-4)" "unprognostic (1.06e-1)" "unprognostic (4.74e-1)" "unprognostic (3.44e-1)" "unprognostic (2.37e-1)" "unprognostic (3.21e-1)" "unprognostic (4.29e-6)" "unprognostic (4.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" IGHV3-38 ENSG00000211958 "Immunoglobulin heavy variable 3-38 (non-functional)" A0A0C4DH36 14 106410493-106411021 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.7;lymphoid tissue: 10.1;urinary bladder: 7.0" "Cell type enriched" "Detected in single" 86 "Plasma cells: 8.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 3.4;naive B-cell: 1.5" "Lineage enriched" "Detected in single" 34 "B-cells: 3.4" "Cancer enriched" "Detected in single" 5 "prostate cancer: 1.4" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 2900000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 60: Prostate cancer - Unknown function" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (1.03e-5)" "unprognostic (5.11e-2)" "unprognostic (3.29e-3)" "unprognostic (1.02e-1)" "unprognostic (1.31e-3)" "unprognostic (8.40e-2)" "unprognostic (3.54e-2)" "unprognostic (2.05e-1)" "unprognostic (1.98e-1)" "unprognostic (1.75e-8)" "unprognostic (6.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.99e-1)" "unprognostic (2.52e-1)" IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 205.9;stomach 1: 305.8;urinary bladder: 148.1" "Cell type enriched" "Detected in some" 36 "Plasma cells: 606.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.5" "Group enriched" "Detected in some" 319 "memory B-cell: 29.5;naive B-cell: 39.2" "Lineage enriched" "Detected in single" 364 "B-cells: 39.2" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 4000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 500.5;lymphoid tissue: 832.0;stomach 1: 393.2" "Cell type enriched" "Detected in some" 71 "Plasma cells: 3482.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.7;medulla oblongata: 1.5;pons: 1.5" "Group enriched" "Detected in some" 527 "memory B-cell: 187.8;naive B-cell: 97.9" "Lineage enriched" "Detected in single" 692 "B-cells: 187.8" "Group enriched" "Detected in some" 285 "lymphoma: 65.7;Myeloma: 21.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 49000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 203.1;lymphoid tissue: 362.0;stomach 1: 176.8;urinary bladder: 96.7" "Cell type enriched" "Detected in some" 81 "Plasma cells: 803.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 186 "memory B-cell: 59.6;naive B-cell: 42.4" "Lineage enriched" "Detected in single" 217 "B-cells: 59.6" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Testis - Late spermatids, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 1600000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 13: Non-specific - Mixed function" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 79.1;lymphoid tissue: 125.8;stomach 1: 42.2" "Cell type enriched" "Detected in some" 68 "Plasma cells: 592.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 98 "memory B-cell: 54.9;naive B-cell: 52.9" "Lineage enriched" "Detected in single" 100 "B-cells: 54.9" "Group enriched" "Detected in some" 113 "Leukemia: 8.2;lymphoma: 19.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 4300000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" IGHV3-64 ENSG00000223648 "Immunoglobulin heavy variable 3-64" A0A075B6Q5 14 106657725-106658258 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.5;breast: 6.9;intestine: 11.4" "Cell type enriched" "Detected in some" 24 "Plasma cells: 64.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 20 "memory B-cell: 11.1" "Lineage enriched" "Detected in single" 111 "B-cells: 11.1" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 4300000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "prognostic favorable (6.09e-6)" "unprognostic (6.52e-2)" "unprognostic (2.11e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-3)" "unprognostic (1.40e-1)" "unprognostic (2.06e-1)" "unprognostic (8.01e-2)" "unprognostic (2.13e-2)" "unprognostic (2.33e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (3.93e-5)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" "unprognostic (3.86e-2)" "unprognostic (1.07e-2)" IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 139.8;lymphoid tissue: 262.8" "Cell type enriched" "Detected in some" 227 "Plasma cells: 1028.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.4;naive B-cell: 18.8" "Lineage enriched" "Detected in single" 420 "B-cells: 43.4" "Cancer enhanced" "Detected in single" "Leukemia: 1.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 2500000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 45.5;intestine: 55.3;urinary bladder: 100.6" "Cell type enriched" "Detected in some" 178 "Plasma cells: 1430.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 135 "memory B-cell: 39.3" "Lineage enriched" "Detected in single" 135 "B-cells: 39.3" "Group enriched" "Detected in some" 17 "Leukemia: 20.0;lymphoma: 26.7;Myeloma: 7.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 7200000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 55: Lymphoma - Immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 445.8;lymphoid tissue: 933.8" "Cell type enriched" "Detected in some" 127 "Plasma cells: 12065.3" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 148 "memory B-cell: 136.5;naive B-cell: 108.1" "Lineage enriched" "Detected in single" 165 "B-cells: 136.5" "Group enriched" "Detected in some" 327 "Leukemia: 220.1;lymphoma: 166.2;Myeloma: 182.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 39000000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" IGHV3-72 ENSG00000225698 "Immunoglobulin heavy variable 3-72" A0A0B4J1Y9 14 106790694-106791233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.2;urinary bladder: 91.7" "Cell type enriched" "Detected in some" 187 "Plasma cells: 1940.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "memory B-cell: 48.4" "Lineage enriched" "Detected in single" 249 "B-cells: 48.4" "Cancer enriched" "Detected in single" 4 "lymphoma: 2.6" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 9600000000 "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (9.10e-6)" "unprognostic (2.18e-2)" "unprognostic (1.32e-2)" "unprognostic (2.93e-2)" "prognostic favorable (8.57e-5)" "unprognostic (9.14e-3)" "unprognostic (3.98e-2)" "unprognostic (1.86e-1)" "unprognostic (9.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (9.29e-2)" "unprognostic (1.29e-1)" "unprognostic (8.81e-2)" "unprognostic (1.32e-1)" IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 137.0;urinary bladder: 79.0" "Cell type enriched" "Detected in some" 157 "Plasma cells: 719.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 87 "memory B-cell: 70.1;naive B-cell: 43.3" "Lineage enriched" "Detected in single" 107 "B-cells: 70.1" "Group enriched" "Detected in some" 232 "lymphoma: 13.6;Myeloma: 32.8" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 3200000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (7.89e-4)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.25e-7)" "unprognostic (4.23e-2)" "unprognostic (4.32e-2)" "unprognostic (5.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (4.37e-2)" IGHV3-74 ENSG00000224650 "Immunoglobulin heavy variable 3-74" A0A0B4J1X5 14 106810442-106811131 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 84.4;salivary gland: 73.5;urinary bladder: 44.9" "Cell type enriched" "Detected in some" 284 "Plasma cells: 11002.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 5 "lymphoma: 39.4" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 27000000000 "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (2.47e-4)" "unprognostic (9.70e-2)" "prognostic favorable (8.33e-4)" "unprognostic (6.96e-3)" "unprognostic (1.42e-1)" "prognostic favorable (7.79e-4)" "unprognostic (1.06e-1)" "unprognostic (7.06e-2)" "unprognostic (3.94e-1)" "unprognostic (3.07e-2)" "unprognostic (2.42e-1)" "unprognostic (9.85e-2)" "prognostic unfavorable (4.70e-6)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 43.5;lymphoid tissue: 84.8;salivary gland: 38.5;stomach 1: 29.9;urinary bladder: 118.6" "Cell type enriched" "Detected in some" 154 "Plasma cells: 234.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 6 "spinal cord: 2.5" "Group enriched" "Detected in some" 207 "memory B-cell: 28.8;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 289 "B-cells: 28.8" "Cancer enriched" "Detected in single" 10 "Myeloma: 3.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 2500000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 7: Non-specific - Ribosome" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 452.7;urinary bladder: 184.7" "Cell type enriched" "Detected in some" 152 "Plasma cells: 1180.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.8" "Group enriched" "Detected in some" 48 "memory B-cell: 43.7;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.7" "Cancer enriched" "Detected in some" 12 "Myeloma: 35.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 710000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 7: Non-specific - Ribosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (1.53e-3)" "unprognostic (9.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.74e-4)" "prognostic favorable (4.64e-5)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.72e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (2.00e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (1.09e-1)" IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "urinary bladder: 261.0" "Cell type enriched" "Detected in some" 155 "Plasma cells: 10926.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "white matter: 2.5" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 100 "lymphoma: 476.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 4300000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 22: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "lymphoid tissue: 365.9;urinary bladder: 522.6" "Cell type enriched" "Detected in some" 359 "Plasma cells: 28207.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 40 "lymphoma: 89.4;Myeloma: 52.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 5000000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 8: Immune cells - Immune response" "Cluster 13: Non-specific - Mixed function" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (5.95e-3)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (2.38e-3)" "unprognostic (4.48e-2)" "unprognostic (2.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.23e-2)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (2.04e-2)" "unprognostic (2.77e-1)" "unprognostic (7.68e-2)" "unprognostic (8.33e-2)" IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 549.8;urinary bladder: 742.3" "Cell type enriched" "Detected in some" 192 "Plasma cells: 1574.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "midbrain: 9.4" "Group enriched" "Detected in some" 23 "memory B-cell: 56.8;naive B-cell: 31.4" "Lineage enriched" "Detected in many" 29 "B-cells: 56.8" "Group enriched" "Detected in some" 49 "lymphoma: 23.3;Myeloma: 69.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 3800000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 46: Brainstem - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.03e-3)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.60e-6)" "unprognostic (2.24e-1)" "unprognostic (6.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (3.16e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 507.2;lymphoid tissue: 883.5;urinary bladder: 679.1" "Cell type enriched" "Detected in some" 154 "Plasma cells: 7286.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 3.7" "Group enriched" "Detected in some" 37 "memory B-cell: 169.4;naive B-cell: 77.5" "Lineage enriched" "Detected in many" 51 "B-cells: 169.4" "Cancer enriched" "Detected in some" 9 "lymphoma: 98.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 5500000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 199.2;lymphoid tissue: 373.6;stomach 1: 138.8" "Cell type enriched" "Detected in some" 33 "Plasma cells: 1616.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.1;naive B-cell: 25.6" "Lineage enriched" "Detected in single" 52 "B-cells: 39.1" "Cancer enriched" "Detected in single" 47 "lymphoma: 20.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 4400000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" IGHV5-10-1 IGHV5-A ENSG00000282651 "Immunoglobulin heavy variable 5-10-1" A0A0J9YXX1 14 106107972-106108464 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 305.4;lymphoid tissue: 548.7" "Cell type enriched" "Detected in some" 246 "Plasma cells: 5947.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "memory B-cell: 75.0;naive B-cell: 67.0" "Lineage enriched" "Detected in many" 16 "B-cells: 75.0" "Group enriched" "Detected in some" 9 "Leukemia: 1.6;lymphoma: 3.4" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA006014 Approved "Immunoglobulin genes" Immunity NA NA 1200000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA006014: " IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "urinary bladder: 336.3" "Cell type enriched" "Detected in some" 113 "Plasma cells: 7180.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 567 "lymphoma: 67.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA006014 Approved "Immunoglobulin genes" Immunity NA NA 2700000000 "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "HPA006014: " "unprognostic (2.03e-3)" "unprognostic (1.00e-1)" "unprognostic (3.21e-2)" "unprognostic (7.65e-3)" "unprognostic (1.80e-2)" "prognostic favorable (5.47e-4)" "unprognostic (2.40e-2)" "unprognostic (1.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.70e-1)" "unprognostic (1.17e-1)" IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "intestine: 430.7" "Cell type enriched" "Detected in some" 130 "Plasma cells: 1530.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 20.0" "Lineage enriched" "Detected in single" 53 "B-cells: 20.0" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 930000000 "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" IGHV7-4-1 ENSG00000282122 "Immunoglobulin heavy variable 7-4-1" A0A0J9YVY3 14 106025145-106025630 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 93.9;lymphoid tissue: 129.4" "Cell type enriched" "Detected in some" 96 "Plasma cells: 8553.1" "Region enhanced" "Detected in some" "cerebral cortex: 1.2;white matter: 1.1" "Group enriched" "Detected in some" 110 "memory B-cell: 8.3;naive B-cell: 13.6" "Lineage enriched" "Detected in single" 137 "B-cells: 13.6" "Cancer enriched" "Detected in single" 97 "lymphoma: 18.4" "Adipose visceral - Plasma cells, Breast - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 560000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" IGHV7-81 ENSG00000211979 "Immunoglobulin heavy variable 7-81 (non-functional)" A0A0B4J1V7 14 106874583-106875071 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.2;lymphoid tissue: 17.7;stomach 1: 12.0" "Group enriched" "Detected in some" 4 "B-cells: 2.9;Plasma cells: 2.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 5.5;naive B-cell: 4.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.5" "Cancer enhanced" "Detected in some" "lymphoma: 8.1;Rhabdoid: 3.8" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 270000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "unprognostic (5.71e-4)" "unprognostic (3.87e-1)" "unprognostic (1.06e-1)" "unprognostic (6.85e-2)" "unprognostic (2.67e-3)" "unprognostic (2.24e-1)" "unprognostic (2.07e-1)" "unprognostic (1.14e-2)" "unprognostic (6.16e-5)" "unprognostic (1.69e-3)" "unprognostic (1.78e-2)" "unprognostic (1.08e-1)" "unprognostic (5.63e-2)" "unprognostic (3.44e-1)" "unprognostic (3.63e-2)" IGHV8-51-1 "IGHV(III)-51-1, IGHVIII-51-1" ENSG00000254167 "Immunoglobulin heavy variable IGHV8-51-1 (non-functional)" 14 106583501-106583807 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "lymphoid tissue: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Leukemia: 3.3" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 59: Leukemia - T-cell receptor" "unprognostic (2.16e-1)" "unprognostic (4.58e-2)" IGIP "C5orf53, LOC492311" ENSG00000182700 "IgA inducing protein" A6NJ69 5 140125937-140129392 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Horizontal cells: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041877, HPA048615" Uncertain Approved Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 Vesicles "HPA041877: AB_2677721, HPA048615: AB_2680462" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" "unprognostic (2.00e-2)" "unprognostic (2.46e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (2.38e-1)" "unprognostic (5.05e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.94e-1)" "prognostic favorable (6.25e-6)" "unprognostic (2.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.98e-2)" "unprognostic (7.77e-2)" IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 33950.8;lymphoid tissue: 61167.3" "Cell type enriched" "Detected in many" 8 "Plasma cells: 258180.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39309.6;naive B-cell: 35339.2" "Lineage enriched" "Detected in all" 23 "B-cells: 39309.6" "Cancer enriched" "Detected in many" 6 "Myeloma: 27290.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB015377 Uncertain "Immunoglobulin genes" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "CAB015377: AB_2251264" "prognostic favorable (6.59e-4)" "unprognostic (1.04e-2)" "unprognostic (3.54e-2)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "prognostic favorable (1.18e-4)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (3.19e-2)" "unprognostic (2.81e-3)" "unprognostic (2.82e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (2.17e-9)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 2997.5;lymphoid tissue: 3221.3;salivary gland: 1199.3;stomach 1: 2368.2;urinary bladder: 1082.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38195.4;naive B-cell: 32246.9;plasmacytoid DC: 14819.2" "Group enriched" "Detected in all" 390 "B-cells: 38195.4;dendritic cells: 14819.2" "Group enriched" "Detected in many" 20 "lymphoma: 636.4;Myeloma: 2236.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 381.2;lymphoid tissue: 764.1" "Cell type enriched" "Detected in some" 199 "Plasma cells: 6634.2" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 261.0;naive B-cell: 165.1" "Lineage enriched" "Detected in single" 1004 "B-cells: 261.0" "Cancer enhanced" "Detected in single" "Myeloma: 2.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 13000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 22: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 269.4;lymphoid tissue: 578.6;urinary bladder: 251.4" "Cell type enriched" "Detected in some" 359 "Plasma cells: 10038.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "choroid plexus: 1.3" "Group enriched" "Detected in some" 522 "memory B-cell: 165.4;naive B-cell: 113.5" "Lineage enriched" "Detected in single" 619 "B-cells: 165.4" "Cancer enriched" "Detected in some" 44 "Myeloma: 129.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 10000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 361.0;lymphoid tissue: 439.5" "Cell type enriched" "Detected in some" 119 "Plasma cells: 3624.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 426 "memory B-cell: 106.2;naive B-cell: 82.7" "Lineage enriched" "Detected in single" 479 "B-cells: 106.2" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 8400000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 258.1;lymphoid tissue: 336.1" "Cell type enriched" "Detected in some" 95 "Plasma cells: 3035.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 683 "memory B-cell: 153.5;naive B-cell: 186.6" "Lineage enriched" "Detected in single" 749 "B-cells: 186.6" "Cancer enriched" "Detected in single" 482 "lymphoma: 158.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 8300000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89268001-89268506 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1666.7;stomach 1: 604.2" "Cell type enriched" "Detected in some" 57 "Plasma cells: 895.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 20.3" "Group enriched" "Detected in some" 366 "memory B-cell: 367.8;naive B-cell: 427.7" "Lineage enriched" "Detected in many" 394 "B-cells: 427.7" "Group enriched" "Detected in some" 145 "lymphoma: 168.4;Myeloma: 47.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 7: Non-specific - Ribosome" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" IGKV1-37 "IGKV137, O14" ENSG00000239862 "Immunoglobulin kappa variable 1-37 (non-functional)" A0A075B6S9 2 89297264-89297785 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 7.9;lymphoid tissue: 16.7;urinary bladder: 5.4" "Cell type enriched" "Detected in some" 14 "Plasma cells: 37.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 249 "memory B-cell: 21.3;naive B-cell: 28.3" "Lineage enriched" "Detected in single" 284 "B-cells: 28.3" "Group enriched" "Detected in some" 21 "lymphoma: 1.8;Myeloma: 2.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 69.5;lymphoid tissue: 52.9;stomach 1: 80.6" "Cell type enriched" "Detected in some" 136 "Plasma cells: 8646.4" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 387 "memory B-cell: 1074.8;naive B-cell: 941.5" "Lineage enriched" "Detected in many" 413 "B-cells: 1074.8" "Cancer enriched" "Detected in some" 9 "Myeloma: 134.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 8000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 749.9;lymphoid tissue: 1415.5;urinary bladder: 913.4" "Cell type enriched" "Detected in some" 171 "Plasma cells: 24096.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 862.6;naive B-cell: 866.9" "Lineage enriched" "Detected in many" 365 "B-cells: 866.9" "Cancer enriched" "Detected in some" 8 "Myeloma: 751.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 8400000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 149.7;lymphoid tissue: 586.5" "Cell type enriched" "Detected in some" 31 "Plasma cells: 714.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 805 "memory B-cell: 124.1;naive B-cell: 86.4" "Lineage enriched" "Detected in single" 949 "B-cells: 124.1" "Group enriched" "Detected in some" 25 "lymphoma: 3.8;Myeloma: 1.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 12000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.6;lymphoid tissue: 53.2;urinary bladder: 40.3" "Cell type enriched" "Detected in some" 25 "Plasma cells: 270.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 313 "memory B-cell: 131.7;naive B-cell: 137.1" "Lineage enriched" "Detected in single" 319 "B-cells: 137.1" "Not detected" "Not detected" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 6100000000 "Cluster 14: Non-specific - Unknown function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 412.4;lymphoid tissue: 650.3;stomach 1: 275.4" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3881.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 706 "memory B-cell: 301.9;naive B-cell: 299.3" "Lineage enriched" "Detected in single" 709 "B-cells: 301.9" "Cancer enriched" "Detected in single" 6 "lymphoma: 3.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 4500000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.8;lung: 11.2;lymphoid tissue: 27.3" "Cell type enriched" "Detected in single" 166 "Plasma cells: 113.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "memory B-cell: 13.0;naive B-cell: 12.3" "Lineage enriched" "Detected in single" 34 "B-cells: 13.0" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 12000000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 100.5;lymphoid tissue: 309.3" "Cell type enriched" "Detected in some" 805 "Plasma cells: 3466.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 736 "memory B-cell: 482.6;naive B-cell: 333.8" "Lineage enriched" "Detected in single" 870 "B-cells: 482.6" "Cancer enriched" "Detected in single" 32 "Myeloma: 22.3" "Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 370000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" IGKV1D-16 ENSG00000241244 "Immunoglobulin kappa variable 1D-16" P01601 2 90100236-90100738 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "gallbladder: 76.1;intestine: 88.6;lymphoid tissue: 160.1" "Cell type enriched" "Detected in some" 19 "Plasma cells: 989.7" "Cancer enhanced" "Detected in many" "lung cancer: 17.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 328 "memory B-cell: 57.9;naive B-cell: 121.3" "Lineage enriched" "Detected in single" 444 "B-cells: 121.3" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 9000000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 55: Lymphoma - Immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "HPA048721: " "prognostic favorable (2.41e-4)" "unprognostic (4.41e-3)" "unprognostic (3.96e-3)" "unprognostic (5.39e-2)" "unprognostic (1.35e-3)" "unprognostic (8.61e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.54e-2)" "unprognostic (6.61e-3)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (4.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.66e-2)" "unprognostic (2.84e-1)" IGKV1D-17 ENSG00000242766 "Immunoglobulin kappa variable 1D-17" A0A075B6S4 2 90082635-90083291 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.6;lymphoid tissue: 4.9" "Cell type enriched" "Detected in some" 7 "Plasma cells: 15.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 60 "memory B-cell: 7.7;naive B-cell: 4.1" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Group enriched" "Detected in some" 7 "Gallbladder cancer: 1.0;Myeloma: 1.2" "Breast - Plasma cells, Pancreas - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 1000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.47e-4)" "unprognostic (4.23e-2)" "unprognostic (2.43e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.68e-4)" "unprognostic (1.19e-1)" "unprognostic (6.18e-2)" "unprognostic (2.27e-1)" "unprognostic (8.86e-2)" "unprognostic (1.74e-5)" "unprognostic (1.38e-1)" "unprognostic (1.56e-2)" "unprognostic (1.17e-1)" "unprognostic (4.04e-3)" IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89914545 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 1.9;lymphoid tissue: 2.1;stomach 1: 2.2;urinary bladder: 1.8" "Cell type enriched" "Detected in some" 501 "Plasma cells: 2537.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.7" "Lineage enriched" "Detected in single" 27 "B-cells: 2.7" "Cancer enhanced" "Detected in single" "lymphoma: 2.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 4900000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (5.10e-3)" "unprognostic (2.03e-1)" "unprognostic (2.11e-2)" "unprognostic (2.03e-4)" "unprognostic (7.90e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-2)" IGKV1D-37 "IGKV1D37, O4" ENSG00000250036 "Immunoglobulin kappa variable 1D-37 (non-functional)" P0DSN7 2 89884740-89885216 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.3;stomach 1: 14.6;urinary bladder: 19.4" "Cell type enriched" "Detected in single" 8 "Plasma cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 208 "memory B-cell: 13.7;naive B-cell: 29.2" "Lineage enriched" "Detected in single" 283 "B-cells: 29.2" "Cancer enriched" "Detected in some" 75 "Myeloma: 260.3" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 6700000000 "Cluster 34: B-cells - Unknown function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "HPA048721: " "unprognostic (2.68e-1)" IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2814.6;lymphoid tissue: 6283.6" "Cell type enriched" "Detected in some" 252 "Plasma cells: 3634.8" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 224 "memory B-cell: 473.3;naive B-cell: 736.4" "Lineage enriched" "Detected in many" 273 "B-cells: 736.4" "Cancer enriched" "Detected in many" 18 "Myeloma: 5094.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" IGKV1D-42 ENSG00000211633 "Immunoglobulin kappa variable 1D-42 (non-functional)" A0A075B6H8 2 90190193-90190681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 45.9;lymphoid tissue: 24.5" "Cell type enriched" "Detected in single" 34 "Plasma cells: 3.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 37 "memory B-cell: 5.6;naive B-cell: 1.6" "Lineage enriched" "Detected in single" 57 "B-cells: 5.6" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 41000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (8.08e-6)" "unprognostic (4.83e-2)" "unprognostic (2.22e-2)" "unprognostic (2.51e-3)" "unprognostic (1.84e-1)" "unprognostic (2.10e-2)" "unprognostic (1.66e-5)" "unprognostic (1.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (1.39e-1)" IGKV1D-43 ENSG00000242580 "Immunoglobulin kappa variable 1D-43" A0A0B4J1Z2 2 90209873-90210529 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.8;lymphoid tissue: 4.7;stomach 1: 3.5" "Cell type enriched" "Detected in some" 48 "Plasma cells: 288.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 153 "memory B-cell: 13.3;naive B-cell: 17.1" "Lineage enriched" "Detected in single" 171 "B-cells: 17.1" "Cancer enhanced" "Detected in single" "Myeloma: 2.3" "Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 380000000 "Cluster 18: Non-specific - Translation" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.32e-5)" "unprognostic (6.71e-2)" "unprognostic (4.01e-2)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (1.37e-3)" "unprognostic (3.15e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-5)" "unprognostic (3.96e-2)" "unprognostic (2.20e-1)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" IGKV1D-8 ENSG00000239819 "Immunoglobulin kappa variable 1D-8" A0A087WSZ0 2 90220727-90221384 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 13.8" "Cell type enriched" "Detected in some" 57 "Plasma cells: 497.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 324 "memory B-cell: 32.9;naive B-cell: 31.9" "Lineage enriched" "Detected in single" 329 "B-cells: 32.9" "Group enriched" "Detected in some" 14 "lymphoma: 1.5;Myeloma: 1.1" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA048721 Approved "Immunoglobulin genes" Immunity NA NA 1900000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "HPA048721: " "prognostic favorable (2.93e-4)" "unprognostic (1.03e-3)" "unprognostic (2.23e-2)" "unprognostic (2.76e-3)" "prognostic favorable (8.80e-5)" "unprognostic (6.07e-2)" "unprognostic (9.76e-3)" "unprognostic (2.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.35e-1)" "unprognostic (9.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" IGKV2-24 ENSG00000241294 "Immunoglobulin kappa variable 2-24" A0A0C4DH68 2 89176328-89177160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 262.7;urinary bladder: 903.4" "Cell type enriched" "Detected in some" 142 "Plasma cells: 3292.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "memory B-cell: 48.3" "Lineage enriched" "Detected in single" 484 "B-cells: 48.3" "Cancer enriched" "Detected in single" 4 "lymphoma: 1.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 840000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 22: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "prognostic favorable (5.74e-6)" "unprognostic (4.92e-3)" "unprognostic (1.04e-2)" "unprognostic (2.38e-2)" "unprognostic (3.79e-3)" "prognostic favorable (1.59e-4)" "unprognostic (5.02e-2)" "unprognostic (1.65e-1)" "unprognostic (2.71e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.82e-5)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1053.8;lymphoid tissue: 1733.5" "Cell type enriched" "Detected in some" 141 "Plasma cells: 1190.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 14 "naive B-cell: 41.1" "Lineage enriched" "Detected in many" 39 "B-cells: 41.1" "Cancer enriched" "Detected in single" 247 "lymphoma: 221.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 34: B-cells - Unknown function" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 607.7;lymphoid tissue: 581.4;stomach 1: 313.6" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13830.9" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 315 "memory B-cell: 561.8;naive B-cell: 326.0" "Lineage enriched" "Detected in many" 398 "B-cells: 561.8" "Cancer enriched" "Detected in some" 11 "lymphoma: 288.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 6800000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" IGKV2-40 ENSG00000273962 "Immunoglobulin kappa variable 2-40" A0A087WW87 2 89330116-89330429 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 41.2" "Cell type enriched" "Detected in single" 79 "Plasma cells: 7.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "memory B-cell: 3.2;naive B-cell: 5.1" "Lineage enriched" "Detected in single" 51 "B-cells: 5.1" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (3.31e-1)" "unprognostic (1.94e-2)" IGKV2D-24 ENSG00000241566 "Immunoglobulin kappa variable 2D-24 (non-functional)" A0A075B6R9 2 90004797-90005629 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 19.0;lymphoid tissue: 24.6;urinary bladder: 14.7" "Cell type enriched" "Detected in single" 109 "Plasma cells: 68.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 8 "cerebral cortex: 1.4;hippocampal formation: 3.8" "Group enriched" "Detected in some" 48 "memory B-cell: 6.8;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.8" "Cancer enriched" "Detected in single" 5 "lymphoma: 1.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 29: Forebrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (1.21e-4)" "unprognostic (1.78e-1)" "prognostic favorable (8.07e-4)" "unprognostic (2.09e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (4.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.74e-5)" "unprognostic (7.60e-2)" "unprognostic (1.57e-2)" "unprognostic (3.85e-1)" "unprognostic (3.47e-1)" IGKV2D-26 ENSG00000211623 "Immunoglobulin kappa variable 2D-26" A0A0A0MRZ7 2 89985922-89986702 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.4;lymphoid tissue: 6.0" "Cell type enriched" "Detected in single" 7 "Plasma cells: 2.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.1" "Group enriched" "Detected in some" 246 "memory B-cell: 21.9;naive B-cell: 27.3" "Lineage enriched" "Detected in single" 273 "B-cells: 27.3" "Cancer enriched" "Detected in single" 19 "lymphoma: 1.8" "Breast - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" Immunity NA NA 1000000000 "Cluster 34: B-cells - Unknown function" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (1.11e-1)" "unprognostic (6.09e-2)" IGKV2D-28 ENSG00000242534 "Immunoglobulin kappa variable 2D-28" P01615 2 89959979-89960748 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.3;intestine: 106.0;lymphoid tissue: 93.9;salivary gland: 116.8;stomach 1: 98.6" "Cell type enriched" "Detected in some" 177 "Plasma cells: 2633.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.3" "Group enriched" "Detected in many" 221 "memory B-cell: 2988.8;naive B-cell: 2094.9" "Lineage enriched" "Detected in all" 260 "B-cells: 2988.8" "Cancer enriched" "Detected in single" 43 "lymphoma: 42.9" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 3500000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 29: Forebrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "unprognostic (3.88e-3)" "unprognostic (2.68e-2)" "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948269 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 241.4;lymphoid tissue: 449.3" "Cell type enriched" "Detected in some" 24 "Plasma cells: 348.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 261 "memory B-cell: 356.8;naive B-cell: 487.7" "Lineage enriched" "Detected in many" 302 "B-cells: 487.7" "Group enriched" "Detected in some" 23 "lymphoma: 5.8;Myeloma: 2.4" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 1500000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 14.8;lymphoid tissue: 32.5;stomach 1: 21.6" "Cell type enriched" "Detected in some" 483 "Plasma cells: 1937.8" "Cancer enhanced" "Detected in some" "stomach cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 376 "memory B-cell: 124.5;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 428 "B-cells: 164.2" "Cancer enriched" "Detected in single" 86 "lymphoma: 35.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.17e-3)" "unprognostic (6.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.98e-4)" "unprognostic (5.74e-3)" "unprognostic (3.19e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.55e-1)" IGKV2D-40 ENSG00000251039 "Immunoglobulin kappa variable 2D-40" P01614 2 89851791-89852493 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 112.7" "Cell type enriched" "Detected in some" 186 "Plasma cells: 792.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 30.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 1093 "memory B-cell: 123.2;naive B-cell: 95.2" "Lineage enriched" "Detected in single" 1233 "B-cells: 123.2" "Cancer enriched" "Detected in some" 882 "Myeloma: 2773.4" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 1900000000 "Cluster 34: B-cells - Unknown function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (5.01e-4)" "unprognostic (1.16e-2)" "unprognostic (8.37e-2)" "unprognostic (6.04e-2)" "prognostic favorable (9.78e-7)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (2.32e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (3.59e-2)" "unprognostic (3.02e-1)" "unprognostic (2.91e-1)" "unprognostic (1.25e-1)" IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 1323.4;lymphoid tissue: 2723.2;stomach 1: 765.4;urinary bladder: 1760.7" "Cell type enriched" "Detected in some" 94 "Plasma cells: 16738.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 15 "spinal cord: 34.2" "Group enriched" "Detected in many" 290 "memory B-cell: 1738.3;naive B-cell: 1408.8" "Lineage enriched" "Detected in many" 321 "B-cells: 1738.3" "Cancer enriched" "Detected in some" 17 "Myeloma: 5519.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" Immunity NA NA 18000000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 7: Non-specific - Ribosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 757.4;lymphoid tissue: 1934.6;urinary bladder: 758.7" "Cell type enriched" "Detected in some" 67 "Plasma cells: 14173.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 562 "memory B-cell: 2253.6;naive B-cell: 1663.0" "Lineage enriched" "Detected in all" 646 "B-cells: 2253.6" "Cancer enriched" "Detected in some" 37 "Myeloma: 745.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" Immunity NA NA 7200000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 22: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2965.7;lymphoid tissue: 5079.6" "Cell type enriched" "Detected in some" 120 "Plasma cells: 38821.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 17.6" "Group enriched" "Detected in many" 327 "memory B-cell: 1609.9;naive B-cell: 1229.8" "Lineage enriched" "Detected in many" 370 "B-cells: 1609.9" "Group enriched" "Detected in many" 367 "lymphoma: 353.5;Myeloma: 1322.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" Immunity NA NA 20000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 18.0;lymphoid tissue: 21.5;salivary gland: 15.4" "Cell type enriched" "Detected in some" 8 "Plasma cells: 10.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 28.0;naive B-cell: 24.5" "Lineage enriched" "Detected in single" 65 "B-cells: 28.0" "Cancer enriched" "Detected in single" 48 "Myeloma: 27.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" Immunity NA NA 850000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "Plasma membrane" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 37.2;lymphoid tissue: 56.7;stomach 1: 26.9" "Cell type enriched" "Detected in some" 89 "Plasma cells: 387.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 469 "memory B-cell: 153.1;naive B-cell: 147.2" "Lineage enriched" "Detected in single" 479 "B-cells: 153.1" "Cancer enriched" "Detected in some" 317 "Myeloma: 396.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" Immunity NA NA 6700000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "Plasma membrane" "HPA047702: " "prognostic favorable (6.40e-5)" "unprognostic (7.90e-3)" "unprognostic (1.91e-2)" "unprognostic (2.24e-3)" "prognostic favorable (5.58e-5)" "unprognostic (2.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.49e-1)" "unprognostic (3.61e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.24e-2)" IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 122.0;lymphoid tissue: 196.2;salivary gland: 52.2;stomach 1: 84.7;urinary bladder: 56.0" "Cell type enriched" "Detected in some" 355 "Plasma cells: 1603.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 190 "memory B-cell: 181.9;naive B-cell: 156.7" "Lineage enriched" "Detected in single" 204 "B-cells: 181.9" "Cancer enriched" "Detected in some" 42 "Myeloma: 3660.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" Immunity NA NA 4800000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 127.0;lymphoid tissue: 267.0" "Cell type enriched" "Detected in some" 53 "Plasma cells: 417.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Group enriched" "Detected in some" 1034 "memory B-cell: 198.1;naive B-cell: 99.4" "Lineage enriched" "Detected in single" 1377 "B-cells: 198.1" "Cancer enriched" "Detected in some" 711 "Myeloma: 2737.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" Immunity NA NA 11000000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.5;lymphoid tissue: 5.3;stomach 1: 4.3;urinary bladder: 5.3" "Cell type enriched" "Detected in single" 455 "Plasma cells: 82.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 37 "memory B-cell: 2.9;naive B-cell: 4.4" "Lineage enriched" "Detected in single" 44 "B-cells: 4.4" "Group enriched" "Detected in some" 24 "lymphoma: 2.6;Myeloma: 3.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA047702 Approved Approved "Plasma membrane" "Immunoglobulin genes" Immunity NA NA 3700000000 "Cluster 34: B-cells - Unknown function" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "Plasma membrane" "HPA047702: " "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (6.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.05e-1)" "unprognostic (4.02e-1)" IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1742.2;lymphoid tissue: 3074.1" "Cell type enriched" "Detected in some" 33 "Plasma cells: 27833.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 590 "memory B-cell: 3048.7;naive B-cell: 3092.7" "Lineage enriched" "Detected in all" 595 "B-cells: 3092.7" "Cancer enriched" "Detected in some" 11 "lymphoma: 582.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA 8500000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" IGKV5-2 "B2, IGKV52" ENSG00000211599 "Immunoglobulin kappa variable 5-2" P06315 2 88897232-88897784 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.8;lymphoid tissue: 80.5" "Cell type enriched" "Detected in some" 164 "Plasma cells: 969.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "memory B-cell: 21.5;naive B-cell: 17.4" "Lineage enriched" "Detected in many" 21 "B-cells: 21.5" "Cancer enriched" "Detected in single" 24 "lymphoma: 11.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA 4700000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (1.77e-3)" "unprognostic (1.26e-2)" "unprognostic (1.34e-1)" "unprognostic (2.49e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.37e-1)" "unprognostic (2.26e-1)" "unprognostic (1.29e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.62e-6)" "unprognostic (2.60e-1)" "unprognostic (2.99e-2)" "unprognostic (1.52e-1)" "unprognostic (7.85e-2)" IGKV6-21 "A26, IGKV621" ENSG00000211611 "Immunoglobulin kappa variable 6-21 (non-functional)" A0A0C4DH24 2 89159751-89160366 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 93.7;lymphoid tissue: 136.6" "Cell type enriched" "Detected in some" 82 "Plasma cells: 945.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 195 "memory B-cell: 29.0;naive B-cell: 9.9" "Lineage enriched" "Detected in single" 290 "B-cells: 29.0" "Cancer enriched" "Detected in single" 9 "Myeloma: 1.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 250000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 20: Myeloma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (1.82e-4)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "unprognostic (2.32e-2)" "unprognostic (1.51e-3)" "unprognostic (1.93e-1)" "unprognostic (6.32e-2)" "unprognostic (4.74e-2)" "unprognostic (8.91e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" IGKV6D-21 "A10, IGKV6D21" ENSG00000225523 "Immunoglobulin kappa variable 6D-21 (non-functional)" A0A0A0MT36 2 90021567-90022185 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 64.5;lymphoid tissue: 148.0;urinary bladder: 220.0" "Cell type enriched" "Detected in some" 4 "Plasma cells: 134.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.4" "Group enriched" "Detected in some" 155 "memory B-cell: 14.2;naive B-cell: 16.6" "Lineage enriched" "Detected in single" 167 "B-cells: 16.6" "Not detected" "Not detected" "Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "prognostic favorable (1.95e-4)" "unprognostic (5.47e-3)" "unprognostic (2.85e-3)" "prognostic favorable (5.25e-5)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (3.45e-7)" "unprognostic (7.23e-2)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (2.07e-1)" IGKV6D-41 ENSG00000211626 "Immunoglobulin kappa variable 6D-41 (non-functional)" A0A0C4DH26 2 90069662-90070238 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.5;intestine: 3.2;lymphoid tissue: 2.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 0.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "memory B-cell: 3.0;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 49 "B-cells: 4.9" "Cancer enriched" "Detected in single" 13 "lymphoma: 1.2" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" Immunity NA NA 32000000 "Cluster 34: B-cells - Unknown function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (3.64e-2)" "unprognostic (4.43e-1)" IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3166.8;lymphoid tissue: 5425.9;stomach 1: 2268.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 745 "memory B-cell: 5791.3;naive B-cell: 5907.8" "Lineage enriched" "Detected in all" 752 "B-cells: 5907.8" "Cancer enriched" "Detected in many" 46 "Myeloma: 14011.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9437.0;lymphoid tissue: 19382.3;stomach 1: 10530.9" "Cell type enriched" "Detected in many" 8 "Plasma cells: 107273.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 36 "memory B-cell: 11410.9;naive B-cell: 10729.1" "Lineage enriched" "Detected in all" 37 "B-cells: 11410.9" "Cancer enriched" "Detected in many" 10 "Myeloma: 14457.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (5.76e-5)" "unprognostic (2.29e-2)" "unprognostic (4.54e-3)" "unprognostic (1.46e-2)" "unprognostic (4.02e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.96e-2)" "unprognostic (7.52e-2)" "unprognostic (7.15e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (4.47e-9)" "unprognostic (2.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" IGLC3 IGLC ENSG00000211679 "Immunoglobulin lambda constant 3 (Kern-Oz+ marker)" P0DOY3 22 22906342-22906803 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3970.7;lymphoid tissue: 7928.0;stomach 1: 4009.5;urinary bladder: 3601.8" "Cell type enriched" "Detected in many" 11 "Plasma cells: 37474.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 34 "memory B-cell: 7287.2;naive B-cell: 6162.3" "Lineage enriched" "Detected in all" 37 "B-cells: 7287.2" "Cancer enriched" "Detected in many" 19 "Myeloma: 12802.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "CAB000050, CAB016533" Supported "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "CAB000050: , CAB016533: AB_629719" "prognostic favorable (2.32e-4)" "unprognostic (1.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.54e-2)" "unprognostic (8.41e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.45e-2)" "unprognostic (4.59e-2)" "unprognostic (8.77e-2)" "prognostic favorable (4.58e-4)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.04e-9)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" "unprognostic (5.97e-2)" IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 86.7;lymphoid tissue: 101.3;salivary gland: 68.3;stomach 1: 110.2" "Cell type enriched" "Detected in some" 4 "Plasma cells: 141.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 244 "memory B-cell: 129.9;naive B-cell: 134.9" "Lineage enriched" "Detected in single" 249 "B-cells: 134.9" "Cancer enriched" "Detected in some" 24 "Myeloma: 3425.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.20e-3)" "unprognostic (5.94e-2)" "unprognostic (3.91e-1)" "unprognostic (2.16e-2)" "prognostic favorable (2.03e-4)" "unprognostic (2.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (2.74e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (1.61e-6)" "unprognostic (2.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 97.1;lymphoid tissue: 52.2;salivary gland: 33.2;stomach 1: 39.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 25 "memory B-cell: 20.1;naive B-cell: 11.1" "Lineage enriched" "Detected in single" 32 "B-cells: 20.1" "Cancer enriched" "Detected in some" 5 "Myeloma: 966.9" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" IGLL1 "14.1, CD179B, IGL5, IGLL, IGVPB" ENSG00000128322 "Immunoglobulin lambda like polypeptide 1" P15814 22 23573125-23580302 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 69.3;testis: 24.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 162.7" "Group enriched" "Detected in some" 5 "endometrial cancer: 0.5;lung cancer: 0.5;stomach cancer: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 12.0;naive B-cell: 14.9" "Lineage enriched" "Detected in many" 11 "B-cells: 14.9" "Group enriched" "Detected in some" 13 "Leukemia: 379.0;lymphoma: 146.4" "Breast - Plasma cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA051134, HPA071406" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" "No annotated function" NA NA 48000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 6: Bone marrow - Innate immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 36: Late spermatids - Unknown function" 2 "Endoplasmic reticulum" "HPA051134: AB_2681356, HPA071406: AB_2686393" "unprognostic (6.21e-2)" "unprognostic (5.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.91e-6)" "unprognostic (1.08e-1)" "unprognostic (5.27e-2)" "unprognostic (6.17e-3)" "unprognostic (5.89e-2)" "unprognostic (9.07e-2)" "unprognostic (1.99e-4)" "unprognostic (2.35e-2)" "unprognostic (5.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.21e-2)" IGLL5 ENSG00000254709 "Immunoglobulin lambda like polypeptide 5" B9A064 22 22887780-22896111 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 397.1;lymphoid tissue: 656.5;stomach 1: 300.1" "Cell type enriched" "Detected in some" 9 "Plasma cells: 1531.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 227 "memory B-cell: 517.6;naive B-cell: 619.6" "Lineage enriched" "Detected in many" 247 "B-cells: 619.6" "Cancer enriched" "Detected in some" 4 "Myeloma: 1179.4" "Secreted to blood" "No annotated function" NA NA 53000000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (6.10e-4)" "unprognostic (7.64e-3)" "unprognostic (4.33e-2)" "unprognostic (1.51e-3)" "unprognostic (2.82e-2)" "prognostic favorable (3.41e-5)" "unprognostic (1.76e-2)" "unprognostic (2.18e-1)" "unprognostic (7.28e-2)" "unprognostic (1.87e-2)" "unprognostic (1.01e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (5.94e-8)" "unprognostic (1.85e-1)" "unprognostic (4.63e-1)" "unprognostic (8.52e-2)" "unprognostic (6.50e-2)" IGLON5 LOC402665 ENSG00000142549 "IgLON family member 5" A6NGN9 19 51311644-51330891 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 64.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.6;Horizontal cells: 69.2;Inhibitory neurons: 16.8;Spermatogonia: 9.5" "Group enriched" "Detected in many" 5 "glioma: 9.2;ovarian cancer: 3.5;testis cancer: 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Neuroblastoma: 15.2;testis cancer: 7.2" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041994 Approved "Secreted in brain" "No annotated function" NA NA 15000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA041994: AB_10794641" "unprognostic (2.09e-1)" "unprognostic (5.76e-2)" "unprognostic (1.80e-2)" "unprognostic (8.87e-3)" "unprognostic (2.33e-1)" "unprognostic (2.66e-1)" "unprognostic (3.47e-4)" "unprognostic (6.38e-5)" "unprognostic (4.54e-2)" "unprognostic (7.89e-3)" "unprognostic (1.59e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (5.62e-7)" "unprognostic (1.77e-2)" "unprognostic (9.28e-2)" "unprognostic (1.36e-2)" "unprognostic (1.86e-3)" IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 260.0;stomach 1: 118.7;urinary bladder: 83.6" "Cell type enriched" "Detected in some" 31 "Plasma cells: 313.3" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 61.2;naive B-cell: 86.2" "Lineage enriched" "Detected in single" 731 "B-cells: 86.2" "Cancer enriched" "Detected in some" 45 "lymphoma: 117.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 980000000 "Cluster 34: B-cells - Unknown function" "Cluster 55: Lymphoma - Immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1251.4;stomach 1: 1249.5" "Cell type enriched" "Detected in some" 237 "Plasma cells: 27451.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 493 "memory B-cell: 669.2;naive B-cell: 580.6" "Lineage enriched" "Detected in many" 528 "B-cells: 669.2" "Cancer enriched" "Detected in some" 14 "Myeloma: 2249.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 2300000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 580.6;lymphoid tissue: 1868.3;stomach 1: 509.4" "Cell type enriched" "Detected in some" 87 "Plasma cells: 8341.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 839 "memory B-cell: 975.4;naive B-cell: 853.6" "Lineage enriched" "Detected in many" 895 "B-cells: 975.4" "Group enriched" "Detected in some" 164 "lymphoma: 40.0;Myeloma: 93.6" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 4000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 683.5;lymphoid tissue: 1747.6" "Cell type enriched" "Detected in some" 10 "Plasma cells: 8877.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 639 "memory B-cell: 1525.2;naive B-cell: 824.7" "Lineage enriched" "Detected in many" 830 "B-cells: 1525.2" "Cancer enriched" "Detected in some" 235 "Myeloma: 3497.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 3000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" IGLV1-50 ENSG00000211645 "Immunoglobulin lambda variable 1-50 (non-functional)" A0A075B6I6 22 22327300-22327814 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.9;lymphoid tissue: 14.2;stomach 1: 19.8" "Cell type enriched" "Detected in single" 1496 "Plasma cells: 882.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "memory B-cell: 11.0;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 33 "B-cells: 11.0" "Group enriched" "Detected in some" 7 "lymphoma: 2.1;Myeloma: 4.3" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.75e-4)" "unprognostic (8.01e-2)" "unprognostic (1.28e-3)" "unprognostic (6.91e-2)" "unprognostic (2.10e-1)" "prognostic favorable (7.08e-4)" "unprognostic (2.81e-1)" "unprognostic (2.41e-1)" "unprognostic (2.02e-1)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (7.38e-2)" "unprognostic (1.58e-4)" "unprognostic (4.89e-3)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-2)" IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1270.8;lymphoid tissue: 2930.7;urinary bladder: 1531.4" "Cell type enriched" "Detected in some" 262 "Plasma cells: 14574.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 277.1;naive B-cell: 179.3" "Lineage enriched" "Detected in many" 11 "B-cells: 277.1" "Group enriched" "Detected in many" 52 "lymphoma: 181.2;Myeloma: 189.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 1700000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 37: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22214794-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 117.4;intestine: 312.0;lymphoid tissue: 318.5;salivary gland: 245.2;stomach 1: 188.7" "Cell type enriched" "Detected in some" 17 "Plasma cells: 208.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 2.0;choroid plexus: 1.4;medulla oblongata: 2.6;white matter: 1.0" "Group enriched" "Detected in some" 32 "memory B-cell: 59.2;naive B-cell: 35.1" "Lineage enriched" "Detected in many" 40 "B-cells: 59.2" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 54000000 "Cluster 34: B-cells - Unknown function" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "prognostic favorable (9.35e-5)" "unprognostic (2.65e-2)" "unprognostic (9.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.29e-1)" "prognostic favorable (8.30e-5)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (3.33e-1)" "unprognostic (5.57e-2)" "unprognostic (5.17e-2)" "unprognostic (3.86e-1)" IGLV11-55 ENSG00000211641 "Immunoglobulin lambda variable 11-55 (non-functional)" A0A075B6I3 22 22201663-22202161 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.1" "Group enriched" "Detected in some" 27 "Late spermatids: 4.5;Plasma cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.9" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 46: Lymphoma - Humoral immune response" "Cluster 36: Late spermatids - Unknown function" "unprognostic (1.22e-1)" "unprognostic (6.16e-2)" IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1495.9;lymphoid tissue: 2834.1" "Cell type enriched" "Detected in some" 97 "Plasma cells: 5094.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1408.5;naive B-cell: 855.5" "Lineage enriched" "Detected in many" 46 "B-cells: 1408.5" "Cancer enriched" "Detected in some" 12 "Myeloma: 2659.7" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 980000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2526.6;lymphoid tissue: 5207.0;stomach 1: 2455.6" "Cell type enriched" "Detected in some" 143 "Plasma cells: 38146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 51 "memory B-cell: 3671.8;naive B-cell: 2675.2" "Lineage enriched" "Detected in all" 59 "B-cells: 3671.8" "Cancer enriched" "Detected in many" 10 "Myeloma: 6526.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 2200000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 261.4;lymphoid tissue: 217.0" "Cell type enriched" "Detected in some" 192 "Plasma cells: 1809.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 322.8;naive B-cell: 127.9" "Lineage enriched" "Detected in many" 64 "B-cells: 322.8" "Cancer enriched" "Detected in some" 1869 "Myeloma: 5114.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 570000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (6.06e-5)" "unprognostic (2.81e-2)" "unprognostic (7.47e-3)" "unprognostic (1.13e-2)" "prognostic favorable (7.75e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (1.95e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 670.1;lymphoid tissue: 1550.8;stomach 1: 652.8" "Cell type enriched" "Detected in some" 75 "Plasma cells: 7101.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 368 "memory B-cell: 2082.0;naive B-cell: 2618.1" "Lineage enriched" "Detected in all" 410 "B-cells: 2618.1" "Cancer enriched" "Detected in some" 24 "Myeloma: 4664.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 540000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" IGLV2-33 ENSG00000211656 "Immunoglobulin lambda variable 2-33 (non-functional)" A0A075B6J2 22 22588155-22588688 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.1;lymphoid tissue: 2.7;salivary gland: 2.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 3.0;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 30 "B-cells: 3.0" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 20: Myeloma - Immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (1.29e-2)" "unprognostic (1.79e-3)" "unprognostic (2.13e-1)" "unprognostic (4.30e-1)" "unprognostic (2.64e-3)" "unprognostic (2.47e-2)" "unprognostic (2.06e-1)" "unprognostic (6.68e-2)" IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1104.8;lymphoid tissue: 982.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 3424.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 125 "memory B-cell: 1445.0;naive B-cell: 2116.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2116.3" "Cancer enriched" "Detected in many" 82 "Myeloma: 4571.8" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 1500000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1188.7;lymphoid tissue: 3222.6;stomach 1: 1416.9" "Cell type enriched" "Detected in some" 61 "Plasma cells: 32733.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 728 "memory B-cell: 783.5;naive B-cell: 1045.8" "Lineage enriched" "Detected in many" 833 "B-cells: 1045.8" "Cancer enriched" "Detected in some" 4 "lymphoma: 146.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003285 Approved "Immunoglobulin genes" Immunity NA NA 4300000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 305.5;lymphoid tissue: 684.8;stomach 1: 280.3" "Cell type enriched" "Detected in some" 89 "Plasma cells: 1050.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "medulla oblongata: 3.4" "Group enriched" "Detected in some" 785 "memory B-cell: 550.8;naive B-cell: 316.8" "Lineage enriched" "Detected in single" 997 "B-cells: 550.8" "Cancer enriched" "Detected in some" 67 "Myeloma: 3522.7" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003285 Approved "Immunoglobulin genes" Immunity NA NA 2000000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "unprognostic (6.00e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.27e-4)" "unprognostic (7.40e-3)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (9.55e-2)" "unprognostic (2.79e-1)" "unprognostic (3.55e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (9.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" IGLV3-12 ENSG00000211667 "Immunoglobulin lambda variable 3-12" A0A075B6K2 22 22771824-22772582 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.2" "Cell type enhanced" "Detected in single" "B-cells: 1.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 4.3;memory B-cell: 9.2;memory CD8 T-cell: 4.0;naive B-cell: 6.8;NK-cell: 5.7" "Group enriched" "Detected in many" 64 "B-cells: 9.2;NK-cells: 5.7;T-cells: 4.3" "Not detected" "Not detected" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 850000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "unprognostic (1.92e-3)" "unprognostic (4.30e-2)" "unprognostic (1.68e-3)" "unprognostic (2.03e-2)" "prognostic favorable (8.39e-6)" "unprognostic (8.44e-2)" "unprognostic (4.62e-2)" "unprognostic (5.01e-2)" "unprognostic (2.88e-2)" "unprognostic (3.15e-4)" "unprognostic (3.62e-2)" "unprognostic (4.71e-1)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" IGLV3-16 ENSG00000211665 "Immunoglobulin lambda variable 3-16" A0A075B6K0 22 22747383-22747921 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 77.8;urinary bladder: 41.3" "Cell type enriched" "Detected in some" 6 "Plasma cells: 39.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 394 "memory B-cell: 107.8;naive B-cell: 122.0" "Lineage enriched" "Detected in single" 418 "B-cells: 122.0" "Cancer enriched" "Detected in single" 398 "Myeloma: 61.3" "Adipose visceral - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 350000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-3)" "unprognostic (4.30e-3)" "unprognostic (4.05e-1)" "prognostic favorable (2.99e-5)" "unprognostic (3.88e-1)" "unprognostic (1.12e-1)" "unprognostic (9.83e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (9.08e-7)" "unprognostic (4.31e-2)" "unprognostic (3.41e-1)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 988.5;lymphoid tissue: 1915.1;stomach 1: 1203.4" "Cell type enriched" "Detected in some" 171 "Plasma cells: 7331.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 353 "memory B-cell: 621.3;naive B-cell: 506.4" "Lineage enriched" "Detected in many" 389 "B-cells: 621.3" "Cancer enriched" "Detected in single" 272 "lymphoma: 199.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 1200000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 22: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1760.6;urinary bladder: 747.9" "Cell type enriched" "Detected in some" 118 "Plasma cells: 5888.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 337 "memory B-cell: 433.3;naive B-cell: 225.5" "Lineage enriched" "Detected in single" 444 "B-cells: 433.3" "Cancer enriched" "Detected in some" 15 "Myeloma: 691.2" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 4700000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (1.75e-3)" "unprognostic (6.04e-3)" "unprognostic (4.21e-2)" "unprognostic (2.59e-3)" "unprognostic (4.06e-3)" "prognostic favorable (3.26e-7)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (3.86e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (9.54e-8)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (7.52e-2)" IGLV3-22 ENSG00000211661 "Immunoglobulin lambda variable 3-22" A0A075B6J6 22 22704265-22704822 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.5;lymphoid tissue: 9.2" "Cell type enriched" "Detected in single" 8 "Plasma cells: 3.2" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 72 "memory B-cell: 6.6;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 78 "B-cells: 7.8" "Cancer enriched" "Detected in single" 11 "Myeloma: 3.0" "Breast - Plasma cells, Lung - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 1100000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (2.00e-1)" "unprognostic (9.93e-3)" "unprognostic (3.73e-1)" IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2361.4;stomach 1: 986.3" "Cell type enriched" "Detected in some" 50 "Plasma cells: 11187.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 547.5;naive B-cell: 799.3" "Lineage enriched" "Detected in many" 53 "B-cells: 799.3" "Cancer enriched" "Detected in some" 14 "Myeloma: 1932.5" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003285 Approved "Immunoglobulin genes" Immunity NA NA 3200000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 388.7" "Cell type enriched" "Detected in some" 140 "Plasma cells: 793.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 720 "memory B-cell: 194.8;naive B-cell: 371.2" "Lineage enriched" "Detected in single" 945 "B-cells: 371.2" "Not detected" "Not detected" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 720000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" IGLV3-32 ENSG00000211657 "Immunoglobulin lambda variable 3-32 (non-functional)" A0A0A0MS00 22 22594528-22595056 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells" "Immunoglobulin genes" Immunity NA NA "unprognostic (4.68e-2)" "unprognostic (1.31e-1)" "unprognostic (7.93e-2)" IGLV3-9 ENSG00000211670 "Immunoglobulin lambda variable 3-9" A0A075B6K5 22 22819010-22819756 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 304.0;stomach 1: 113.8" "Cell type enriched" "Detected in some" 120 "Plasma cells: 251.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.6" "Group enriched" "Detected in many" 52 "memory B-cell: 64.9;naive B-cell: 170.3" "Lineage enriched" "Detected in many" 75 "B-cells: 170.3" "Cancer enriched" "Detected in some" 4 "Myeloma: 5.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003285 Approved "Immunoglobulin genes" Immunity NA NA 1500000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 18: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "HPA003285: AB_1079122" "prognostic favorable (2.59e-4)" "unprognostic (6.52e-3)" "unprognostic (1.95e-1)" "unprognostic (5.40e-2)" "prognostic favorable (9.80e-5)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.47e-2)" "unprognostic (4.58e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-1)" IGLV4-3 ENSG00000211672 "Immunoglobulin lambda variable 4-3" A0A075B6K6 22 22871507-22872035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 15.2;stomach 1: 28.1" "Cell type enriched" "Detected in some" 18 "Plasma cells: 28.5" "Cancer enhanced" "Detected in many" "lung cancer: 4.6" "Region enhanced" "Detected in single" "medulla oblongata: 1.1" "Group enriched" "Detected in some" 98 "memory B-cell: 11.8;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 119 "B-cells: 11.8" "Group enriched" "Detected in some" 35 "Leukemia: 30.3;Myeloma: 79.8" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Immunoglobulin genes" Immunity NA NA 1600000 "Cluster 34: B-cells - Unknown function" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (7.22e-2)" "unprognostic (5.51e-3)" "unprognostic (2.71e-1)" "unprognostic (4.37e-4)" "unprognostic (1.87e-1)" "unprognostic (2.74e-1)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 187.1;lymphoid tissue: 113.2;urinary bladder: 179.2" "Cell type enriched" "Detected in some" 79 "Plasma cells: 726.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 77 "memory B-cell: 79.7;naive B-cell: 49.2" "Lineage enriched" "Detected in single" 95 "B-cells: 79.7" "Group enriched" "Detected in some" 16 "Leukemia: 234.7;lymphoma: 729.3" "Breast - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 120000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 55: Lymphoma - Immune response" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 417.3;lymphoid tissue: 446.6;salivary gland: 112.8;stomach 1: 277.5;urinary bladder: 197.4" "Cell type enriched" "Detected in some" 53 "Plasma cells: 4999.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 2.1" "Group enriched" "Detected in some" 301 "memory B-cell: 333.0;naive B-cell: 225.3" "Lineage enriched" "Detected in single" 359 "B-cells: 333.0" "Cancer enriched" "Detected in single" 405 "lymphoma: 277.1" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 320000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" IGLV5-37 ENSG00000211654 "Immunoglobulin lambda variable 5-37" A0A075B6J1 22 22427540-22428035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 23.8;intestine: 10.1;lymphoid tissue: 40.1;salivary gland: 10.3;stomach 1: 16.0" "Group enriched" "Detected in some" 4 "B-cells: 2.8;Plasma cells: 7.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 54 "memory B-cell: 6.2;naive B-cell: 7.0" "Lineage enriched" "Detected in single" 58 "B-cells: 7.0" "Not detected" "Not detected" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 14000000 "Cluster 34: B-cells - Unknown function" "Cluster 55: Lymphoma - Immune response" "Cluster 61: Plasma cells - Immunoglobulins & histones" "prognostic favorable (4.69e-4)" "unprognostic (2.44e-2)" "unprognostic (5.68e-3)" "unprognostic (4.26e-1)" "prognostic favorable (4.71e-4)" "unprognostic (4.97e-2)" "unprognostic (3.56e-2)" "unprognostic (3.15e-1)" "unprognostic (5.34e-6)" "unprognostic (1.66e-1)" "unprognostic (4.32e-1)" "unprognostic (1.25e-1)" IGLV5-45 ENSG00000211650 "Immunoglobulin lambda variable 5-45" A0A087WSX0 22 22375986-22376505 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 39.1;salivary gland: 8.3;urinary bladder: 11.5" "Cell type enriched" "Detected in some" 68 "Plasma cells: 4034.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.2;naive B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.2" "Cancer enriched" "Detected in single" 16 "Myeloma: 2.2" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 160000000 "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "prognostic favorable (4.62e-4)" "unprognostic (6.18e-2)" "unprognostic (2.26e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.58e-3)" "unprognostic (2.77e-1)" "unprognostic (8.89e-2)" "unprognostic (1.06e-1)" "unprognostic (5.16e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.95e-6)" "unprognostic (6.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (8.36e-2)" IGLV5-48 ENSG00000211647 "Immunoglobulin lambda variable 5-48 (non-functional)" A0A075B6I7 22 22352940-22353433 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.2;lymphoid tissue: 5.1;urinary bladder: 2.6" "Cell type enriched" "Detected in some" 10 "Plasma cells: 32.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 62 "memory B-cell: 5.4;naive B-cell: 6.8" "Lineage enriched" "Detected in single" 69 "B-cells: 6.8" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (3.76e-3)" "unprognostic (1.91e-2)" "unprognostic (9.43e-2)" "unprognostic (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-2)" "unprognostic (2.97e-1)" IGLV5-52 ENSG00000211643 "Immunoglobulin lambda variable 5-52" A0A0A0MRZ9 22 22318727-22319226 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 25 "B-cells: 1.5;Plasma cells: 3.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 11.7;naive B-cell: 10.3" "Lineage enriched" "Detected in many" 6 "B-cells: 11.7" "Low cancer specificity" "Detected in all" "Immunoglobulin genes" Immunity NA NA 1200000 "Cluster 14: Non-specific - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (7.26e-2)" "unprognostic (7.05e-2)" "unprognostic (1.86e-2)" "unprognostic (4.66e-1)" "unprognostic (1.29e-1)" "unprognostic (7.61e-5)" "unprognostic (1.22e-1)" "unprognostic (1.89e-1)" "unprognostic (8.45e-2)" "unprognostic (1.51e-1)" "unprognostic (3.93e-2)" "unprognostic (2.25e-3)" "unprognostic (7.75e-2)" "unprognostic (3.51e-2)" "unprognostic (1.57e-1)" "unprognostic (5.46e-2)" IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1752.9;urinary bladder: 652.7" "Cell type enriched" "Detected in some" 150 "Plasma cells: 7810.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 11 "memory B-cell: 355.6;naive B-cell: 294.1" "Lineage enriched" "Detected in many" 13 "B-cells: 355.6" "Cancer enriched" "Detected in some" 6 "lymphoma: 204.4" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA028862 Supported "Immunoglobulin genes" Immunity NA NA 1900000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA028862: " "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.8;lymphoid tissue: 231.1;stomach 1: 112.5" "Cell type enriched" "Detected in some" 49 "Plasma cells: 902.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 324 "memory B-cell: 132.7;naive B-cell: 54.5" "Lineage enriched" "Detected in single" 459 "B-cells: 132.7" "Cancer enhanced" "Detected in single" "lymphoma: 1.8" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003182 Approved "Immunoglobulin genes" Immunity NA NA 130000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 61: Plasma cells - Immunoglobulins & histones" "HPA003182: " "prognostic favorable (6.49e-6)" "unprognostic (7.85e-3)" "prognostic favorable (7.00e-4)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "prognostic favorable (3.08e-5)" "unprognostic (7.63e-3)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 385.9;lymphoid tissue: 444.8;stomach 1: 243.4;urinary bladder: 428.8" "Cell type enriched" "Detected in some" 202 "Plasma cells: 5326.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "hypothalamus: 3.1" "Group enriched" "Detected in some" 378 "memory B-cell: 184.5;naive B-cell: 82.7" "Lineage enriched" "Detected in single" 522 "B-cells: 184.5" "Cancer enriched" "Detected in single" 5 "lymphoma: 2.9" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" HPA003182 Approved "Immunoglobulin genes" Immunity NA NA 270000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (3.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (3.94e-3)" "unprognostic (4.25e-3)" "unprognostic (4.68e-3)" "unprognostic (1.74e-1)" "unprognostic (2.77e-2)" "unprognostic (7.47e-3)" "unprognostic (2.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" IGLV8-61 ENSG00000211638 "Immunoglobulin lambda variable 8-61" A0A075B6I0 22 22098700-22099212 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 781.2;lymphoid tissue: 951.8" "Group enriched" "Detected in some" 5 "B-cells: 9.3;Plasma cells: 12.5" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "cerebral cortex: 3.3;choroid plexus: 1.7;pons: 1.3;spinal cord: 1.3;white matter: 1.6" "Group enriched" "Detected in some" 633 "memory B-cell: 259.2;naive B-cell: 534.4" "Lineage enriched" "Detected in single" 852 "B-cells: 534.4" "Cancer enriched" "Detected in some" 6 "lymphoma: 12.1" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Low region specificity" "Detected in all" "Immunoglobulin genes" Immunity NA NA 620000000 "Cluster 14: Non-specific - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "unprognostic (1.07e-3)" "unprognostic (2.73e-2)" "prognostic favorable (3.84e-4)" "unprognostic (1.07e-2)" "unprognostic (5.24e-2)" "unprognostic (1.04e-3)" "unprognostic (1.65e-1)" "unprognostic (1.75e-3)" "unprognostic (2.05e-1)" "unprognostic (2.11e-1)" "unprognostic (3.32e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 121.1;lymphoid tissue: 114.9" "Cell type enriched" "Detected in some" 7 "Plasma cells: 40.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 674 "memory B-cell: 70.6;naive B-cell: 88.6" "Lineage enriched" "Detected in single" 751 "B-cells: 88.6" "Cancer enriched" "Detected in single" 89 "lymphoma: 40.8" "Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Immunoglobulin genes" Immunity NA NA 43000000 "Cluster 14: Non-specific - Unknown function" "Cluster 37: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (3.04e-5)" "unprognostic (4.30e-3)" "unprognostic (1.83e-2)" "unprognostic (5.61e-2)" "prognostic favorable (2.00e-5)" "unprognostic (6.29e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (1.66e-1)" "unprognostic (3.07e-1)" "unprognostic (3.90e-2)" "unprognostic (7.16e-2)" IGSF1 "IGCD1, IGDC1, INHBP, KIAA0364, MGC75490, PGSF2" ENSG00000147255 "Immunoglobulin superfamily member 1" Q8N6C5 X 131273506-131578899 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pituitary gland: 163.3" "Cell type enhanced" "Detected in some" "Astrocytes: 3.7;Bipolar cells: 10.7;Breast glandular cells: 3.7;Granulosa cells: 3.2;Pancreatic endocrine cells: 5.1;Schwann cells: 9.2" "Cancer enriched" "Detected in many" 8 "thyroid cancer: 65.8" "Region enhanced" "Detected in all" "hypothalamus: 153.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 9.0" "Breast - Breast glandular cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in all" "hypothalamus: 144.1" "Low region specificity" "Detected in all" "HPA012732, HPA035582" Enhanced Approved Cytosol "Intracellular and membrane" Receptor NA NA 100000 "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Bipolar cells - Visual perception" Cytosol "HPA012732: AB_2732404, HPA035582: AB_2674687" "unprognostic (1.40e-3)" "unprognostic (1.79e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (4.25e-8)" "unprognostic (1.01e-1)" "unprognostic (2.40e-2)" "unprognostic (1.90e-3)" "unprognostic (2.52e-3)" "unprognostic (8.03e-3)" "unprognostic (9.36e-2)" "unprognostic (5.65e-2)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (5.96e-2)" "unprognostic (1.66e-1)" "unprognostic (2.35e-1)" "unprognostic (5.13e-2)" IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151461061 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 12.6;ovary: 17.2" "Cell type enhanced" "Detected in many" "Early spermatids: 205.4;Late spermatids: 41.4;Microglial cells: 59.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 11.8;Rhabdoid: 9.2" "Colon - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" "Developmental protein" NA NA 540000 "Cluster 62: Connective tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 18: Early spermatids - Unknown function" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" IGSF21 "MGC15730, RP11-121A23.1" ENSG00000117154 "Immunoglobin superfamily member 21" Q96ID5 1 18107798-18378483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 95.0" "Group enriched" "Detected in some" 4 "Bipolar cells: 164.7;Excitatory neurons: 79.4;Microglial cells: 71.6;Oligodendrocyte precursor cells: 132.5" "Group enriched" "Detected in many" 5 "breast cancer: 4.1;glioma: 8.6;prostate cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.6;lung cancer: 3.4;thyroid cancer: 7.6" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA NA 23000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.50e-3)" "unprognostic (7.06e-2)" "unprognostic (3.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-2)" "unprognostic (7.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.34e-2)" "unprognostic (2.33e-1)" "unprognostic (7.85e-4)" "unprognostic (3.76e-5)" "unprognostic (2.10e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-2)" IHH "BDA1, HHG2" ENSG00000163501 "Indian hedgehog signaling molecule" Q14623 2 219054424-219060921 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 13.6;intestine: 21.7;stomach 1: 14.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 40.8;Enteroendocrine cells: 49.3;Gastric mucus-secreting cells: 12.4;Intestinal goblet cells: 40.6;Paneth cells: 13.9;Prostatic glandular cells: 17.1;Proximal enterocytes: 18.1;Undifferentiated cells: 18.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.8;endometrial cancer: 30.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 13.8;Gastric cancer: 11.1;liver cancer: 7.1" "Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Developmental protein" NA NA 23000000 "Cluster 45: Intestine - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.63e-2)" "prognostic favorable (3.67e-6)" "unprognostic (4.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.28e-1)" "unprognostic (1.06e-1)" "unprognostic (5.86e-2)" "unprognostic (2.74e-1)" "unprognostic (6.31e-2)" "unprognostic (3.33e-3)" "unprognostic (1.81e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-1)" "unprognostic (1.51e-2)" "unprognostic (2.91e-2)" IL10 "CSIF, IL-10, IL10A, TGIF" ENSG00000136634 "Interleukin 10" P22301 1 206767602-206774541 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 5.4;lymphoid tissue: 6.7" "Group enriched" "Detected in some" 6 "Hofbauer cells: 32.4;Kupffer cells: 56.2;Langerhans cells: 44.9;Macrophages: 114.5;monocytes: 118.4" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "thalamus: 5.7" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6;intermediate monocyte: 1.3" "Lineage enriched" "Detected in single" 5 "monocytes: 1.6" "Cancer enriched" "Detected in some" 8 "lymphoma: 15.9" "Adipose subcutaneous - Macrophages, Testis - Late spermatids, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB013120, HPA071391" Approved "Secreted to blood" Interleukin NA NA 5670 "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 8 "CAB013120: , HPA071391: " "unprognostic (3.65e-2)" "unprognostic (1.14e-1)" "unprognostic (1.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.20e-1)" "unprognostic (2.63e-3)" "unprognostic (2.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" "unprognostic (4.26e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-1)" "unprognostic (4.66e-4)" "unprognostic (7.11e-2)" "unprognostic (1.93e-2)" "unprognostic (2.73e-1)" "unprognostic (1.96e-2)" IL11 "AGIF, IL-11" ENSG00000095752 "Interleukin 11" P20809 19 55364382-55370463 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.4" "Cell type enriched" "Detected in some" 4 "Pancreatic endocrine cells: 127.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 34800 "Cluster 65: Cerebellum - Nervous system development" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 3 "unprognostic (6.60e-3)" "unprognostic (7.23e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (3.32e-3)" "unprognostic (6.33e-2)" "unprognostic (1.04e-2)" "unprognostic (7.84e-5)" "unprognostic (2.47e-1)" "unprognostic (2.52e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (4.83e-2)" "unprognostic (4.07e-8)" "unprognostic (1.23e-1)" "unprognostic (1.41e-1)" "unprognostic (3.82e-3)" "unprognostic (3.08e-2)" IL11RA ENSG00000137070 "Interleukin 11 receptor subunit alpha" Q14626 9 34652162-34661902 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Receptor "Craniosynostosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 49.2;Late spermatids: 98.4;Sertoli cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.6" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013162, CAB032830, HPA036652, HPA036653" Supported Approved "Vesicles,Plasma membrane" "Secreted to blood" Receptor NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 66: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 53: Fibroblasts - ECM organization" 1 "Vesicles, Plasma membrane" "CAB032830: AB_2123745, HPA013162: AB_2668790, HPA036652: AB_2675229, HPA036653: " "unprognostic (7.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.05e-1)" "unprognostic (6.76e-3)" "unprognostic (1.67e-1)" "unprognostic (1.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.52e-2)" "unprognostic (1.89e-2)" "unprognostic (4.02e-1)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (2.14e-1)" "unprognostic (1.51e-1)" "unprognostic (2.93e-2)" "unprognostic (8.71e-2)" IL12A "CLMF, IL-12A, NFSK, NKSF1, p35" ENSG00000168811 "Interleukin 12A" P29459 3 159988835-159996019 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 4.2;Oligodendrocyte precursor cells: 3.8;Plasma cells: 2.9;Schwann cells: 4.0;Spermatogonia: 2.7;Squamous epithelial cells: 2.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 2.6" "Not detected" "Not detected" HPA001886 Uncertain "Secreted to blood" Interleukin NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Neurons - Synaptic function" 1 "HPA001886: AB_1079132" "unprognostic (6.23e-2)" "unprognostic (7.82e-5)" "unprognostic (1.25e-1)" "unprognostic (3.10e-2)" "unprognostic (4.22e-1)" "unprognostic (7.18e-2)" "unprognostic (4.18e-5)" "unprognostic (2.22e-1)" "unprognostic (1.91e-1)" "unprognostic (1.07e-2)" "unprognostic (1.28e-1)" "unprognostic (2.31e-2)" "unprognostic (9.57e-10)" "unprognostic (1.62e-1)" "unprognostic (1.42e-1)" "unprognostic (1.16e-1)" "unprognostic (9.61e-2)" IL12B "CLMF, CLMF2, IL-12B, NKSF, NKSF2" ENSG00000113302 "Interleukin 12B" P29460 5 159314780-159330863 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.3" "Cell type enriched" "Detected in single" 4 "Langerhans cells: 2.0" "Cancer enriched" "Detected in single" 20 "testis cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "lymphoma: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA040970 Supported "Secreted to blood" Interleukin NA NA 140000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 2 "HPA040970: AB_10796234" "unprognostic (5.96e-5)" "unprognostic (4.59e-5)" "unprognostic (1.05e-1)" "unprognostic (3.40e-1)" "unprognostic (9.13e-4)" "unprognostic (6.89e-2)" "unprognostic (2.58e-4)" "unprognostic (6.69e-3)" "unprognostic (3.83e-2)" "unprognostic (4.50e-2)" "unprognostic (2.53e-1)" "unprognostic (7.15e-3)" "unprognostic (9.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-2)" IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.7" "Cell type enhanced" "Detected in some" "Kupffer cells: 12.2;monocytes: 36.4;NK-cells: 54.6;Plasma cells: 11.0;T-cells: 26.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 14 "Leukemia: 9.4;lymphoma: 19.8;Myeloma: 26.5" "Breast - T-cells, Lung - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" IL12RB2 ENSG00000081985 "Interleukin 12 receptor subunit beta 2" Q99665 1 67307364-67398724 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 6.4;skeletal muscle: 3.4" "Group enriched" "Detected in some" 4 "Erythroid cells: 5.7;Excitatory neurons: 21.7;Hofbauer cells: 8.9;Inhibitory neurons: 15.8;Melanocytes: 8.6;NK-cells: 18.0;T-cells: 14.9" "Group enriched" "Detected in many" 4 "cervical cancer: 1.8;head and neck cancer: 2.5;melanoma: 5.6;renal cancer: 1.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 4.8;NK-cell: 15.9" "Group enriched" "Detected in many" 41 "NK-cells: 15.9;T-cells: 4.8" "Cancer enhanced" "Detected in some" "Leukemia: 4.0;skin cancer: 5.2" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "Low region specificity" "Detected in all" HPA024168 Uncertain Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Plasma membrane" "HPA024168: AB_1851629" "unprognostic (1.32e-1)" "unprognostic (1.54e-3)" "unprognostic (2.09e-1)" "unprognostic (2.68e-2)" "unprognostic (2.82e-2)" "unprognostic (1.09e-3)" "unprognostic (2.37e-2)" "unprognostic (3.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.38e-2)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (1.08e-3)" "unprognostic (1.82e-1)" "unprognostic (4.69e-2)" "unprognostic (7.11e-3)" "unprognostic (1.90e-1)" IL13 "ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600" ENSG00000169194 "Interleukin 13" P35225 5 132656263-132661110 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 44 "testis: 23.6" "Cell type enhanced" "Detected in some" "Early spermatids: 103.1;granulocytes: 122.5;Late spermatids: 199.5;Spermatocytes: 35.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 45 "lymphoma: 4.8" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 40000 "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 36: Late spermatids - Unknown function" 2 "unprognostic (2.17e-1)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.92e-1)" "unprognostic (5.21e-3)" "unprognostic (1.79e-1)" "unprognostic (2.69e-1)" "unprognostic (5.20e-1)" "unprognostic (7.10e-2)" "unprognostic (3.61e-3)" "unprognostic (3.34e-1)" "unprognostic (5.97e-4)" "unprognostic (4.70e-2)" "unprognostic (2.05e-1)" "unprognostic (7.39e-2)" "unprognostic (1.38e-1)" IL13RA1 "CD213a1, IL-13Ra, NR4" ENSG00000131724 "Interleukin 13 receptor subunit alpha 1" P78552 X 118727133-118794535 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 181.7;Macrophages: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 10.9;eosinophil: 12.1;myeloid DC: 17.2;neutrophil: 29.0" "Group enriched" "Detected in many" 7 "dendritic cells: 17.2;granulocytes: 29.0;monocytes: 10.9" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA 17000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" 4 "unprognostic (5.14e-3)" "unprognostic (4.72e-2)" "unprognostic (7.12e-2)" "unprognostic (7.75e-2)" "unprognostic (8.81e-3)" "unprognostic (3.82e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.44e-1)" "unprognostic (1.90e-1)" "unprognostic (8.21e-2)" "prognostic unfavorable (1.19e-8)" "unprognostic (1.88e-2)" "unprognostic (2.37e-2)" "unprognostic (2.82e-2)" "unprognostic (5.08e-2)" IL15 "IL-15, MGC9721" ENSG00000164136 "Interleukin 15" P40933 4 141636583-141733987 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 78.2;monocytes: 52.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004457, HPA037738" Approved Supported "Nucleoplasm,Nuclear speckles" "Secreted to blood" Interleukin NA NA 182000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: Endometrial stromal cells - Transcription" 2 "Nucleoplasm, Nuclear speckles" "CAB004457: AB_2124575, HPA037738: AB_2675640" "unprognostic (1.10e-2)" "unprognostic (1.53e-1)" "unprognostic (1.04e-2)" "unprognostic (8.57e-2)" "unprognostic (8.77e-3)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (2.90e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (5.20e-2)" "unprognostic (1.74e-2)" "unprognostic (3.75e-2)" "unprognostic (1.09e-1)" "unprognostic (4.03e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" IL15RA "CD215, IL-15RA" ENSG00000134470 "Interleukin 15 receptor subunit alpha" Q13261 10 5943639-5978187 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 35.8;Exocrine glandular cells: 36.4;Fibroblasts: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" CAB026215 Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 57: Lung - Lung function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 53: Fibroblasts - ECM organization" 3 "Plasma membrane, Cytosol" "CAB026215: " "unprognostic (2.86e-2)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (4.45e-2)" "unprognostic (7.87e-2)" "unprognostic (5.49e-2)" "prognostic unfavorable (2.67e-6)" "unprognostic (5.09e-3)" "unprognostic (1.82e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.35e-4)" "unprognostic (6.18e-3)" "prognostic unfavorable (1.27e-12)" "unprognostic (4.43e-2)" "unprognostic (4.69e-2)" "unprognostic (4.08e-2)" "unprognostic (5.75e-2)" IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 68.3;lymphoid tissue: 131.7" "Cell type enhanced" "Detected in many" "B-cells: 122.8;dendritic cells: 116.3;Kupffer cells: 162.5;Langerhans cells: 107.8;monocytes: 57.9;NK-cells: 86.1;Plasma cells: 70.9;T-cells: 69.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 116.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 25 "Leukemia: 33.0;lymphoma: 45.6;Myeloma: 44.7;skin cancer: 15.3" "Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.1" "Region enriched" "Detected in many" 12 "cerebellum: 62.9" "CAB005247, HPA018467, HPA048861" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" Interleukin NA NA 208000 7300 "Cluster 35: Neutrophils - Protein binding" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" IL17A "CTLA8, IL-17, IL-17A, IL17" ENSG00000112115 "Interleukin 17A" Q16552 6 52186375-52190638 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in some" 10 "T-cells: 23.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052258 Uncertain "Secreted to blood" Interleukin NA NA 9920 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 20: Myeloma - Immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "HPA052258: " "unprognostic (5.55e-1)" "unprognostic (2.18e-4)" "unprognostic (3.05e-4)" "unprognostic (1.41e-2)" "unprognostic (2.22e-2)" IL17B "IL-17B, IL-20, MGC138900, MGC138901, NIRF, ZCYTO7" ENSG00000127743 "Interleukin 17B" Q9UHF5 5 149371324-149404202 "Cancer-related genes, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 36.3;Peritubular cells: 13.1;Sertoli cells: 19.0;Skeletal myocytes: 7.8;Smooth muscle cells: 8.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 12 "basophil: 1.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.2" "Cancer enriched" "Detected in some" 9 "Brain cancer: 11.6" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Sertoli cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA042441 Uncertain "Secreted to blood" Interleukin NA NA 75000 "Cluster 46: Basophils - Proteolysis" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 2: Neurons - Nucleosome" "Cluster 38: Non-specific - Transcription" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA042441: AB_10797014" "unprognostic (2.83e-4)" "unprognostic (2.71e-2)" "unprognostic (4.90e-3)" "unprognostic (9.22e-2)" "unprognostic (7.43e-2)" "unprognostic (5.03e-2)" "unprognostic (9.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.80e-1)" "unprognostic (6.54e-2)" "unprognostic (9.30e-3)" "unprognostic (3.22e-1)" "unprognostic (6.98e-8)" "unprognostic (2.66e-1)" "unprognostic (1.53e-1)" "unprognostic (6.47e-2)" "unprognostic (1.10e-1)" IL17C "CX2, IL-17C, IL-21, MGC126884, MGC138401" ENSG00000124391 "Interleukin 17C" Q9P0M4 16 88638572-88640468 "Predicted secreted proteins" "Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 2.0;urinary bladder: 1.6" "Group enriched" "Detected in some" 10 "Basal respiratory cells: 406.7;Ionocytes: 292.7" "Cancer enhanced" "Detected in some" "stomach cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA065051 Supported "Secreted to blood" Interleukin NA NA 30500 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 70: DU4475 - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA065051: AB_2685413" "unprognostic (1.60e-1)" "unprognostic (1.69e-1)" "unprognostic (7.31e-2)" "unprognostic (4.45e-1)" "unprognostic (5.58e-2)" "unprognostic (2.93e-2)" "unprognostic (3.50e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-2)" "unprognostic (3.46e-1)" "unprognostic (1.89e-2)" "unprognostic (3.04e-3)" "unprognostic (2.73e-2)" "unprognostic (7.91e-2)" "unprognostic (3.56e-3)" "unprognostic (8.37e-3)" IL17D "FLJ30846, IL-17D, IL-27, IL27" ENSG00000172458 "Interleukin 17D" Q8TAD2 13 20702127-20723098 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 151.2;skeletal muscle: 126.4" "Cell type enhanced" "Detected in many" "Astrocytes: 60.7;Early spermatids: 20.2;Excitatory neurons: 16.9;Late spermatids: 36.8;Muller glia cells: 23.1;Oligodendrocyte precursor cells: 19.3;Skeletal myocytes: 28.3" "Group enriched" "Detected in many" 9 "glioma: 10.8;melanoma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Interleukin NA NA 25000 "Cluster 33: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 53: Fibroblasts - ECM organization" "unprognostic (1.76e-2)" "unprognostic (2.05e-1)" "unprognostic (1.38e-2)" "unprognostic (2.23e-1)" "unprognostic (4.26e-2)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "unprognostic (1.37e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.35e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.32e-1)" "unprognostic (7.93e-2)" "unprognostic (5.97e-2)" IL17F "IL-17F, ML-1, ML1" ENSG00000112116 "Interleukin 17F" Q96PD4 6 52236681-52245689 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" Cytokine "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 2.1" "Cell type enriched" "Detected in single" 6 "T-cells: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 85 "lymphoma: 18.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 30000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "unprognostic (1.40e-1)" "unprognostic (1.20e-1)" "unprognostic (3.02e-1)" "unprognostic (2.52e-1)" IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115693 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.7" "Cell type enhanced" "Detected in all" "dendritic cells: 77.9;Kupffer cells: 83.4;Macrophages: 65.6;monocytes: 60.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 15.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Lung - Neutrophil_2, Skin - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" Receptor NA NA 62000 "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.92e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (9.83e-2)" "unprognostic (7.66e-2)" "unprognostic (5.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.96e-2)" "prognostic favorable (8.35e-4)" "unprognostic (2.16e-2)" "unprognostic (1.27e-1)" "unprognostic (6.51e-3)" IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 17.6;cervix: 17.4;kidney: 57.7;liver: 32.3" "Cell type enhanced" "Detected in many" "Astrocytes: 45.8;Oligodendrocyte precursor cells: 35.4;Proximal tubular cells: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" IL17RE FLJ23658 ENSG00000163701 "Interleukin 17 receptor E" Q8NFR9 3 9902612-9916402 "Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.2;skin 1: 30.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 74.7;Enteroendocrine cells: 36.9;Gastric mucus-secreting cells: 49.5;Intestinal goblet cells: 63.4;Paneth cells: 41.7;Proximal enterocytes: 67.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 2.9;cerebellum: 4.0;hypothalamus: 1.3;medulla oblongata: 1.4;pons: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Alveolar cells type 1" "Region enhanced" "Detected in single" "cerebellum: 1.5" HPA019011 Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 45: Intestine - Digestion" "Cluster 37: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA019011: AB_1851667" "unprognostic (1.08e-2)" "unprognostic (7.58e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-3)" "unprognostic (1.09e-1)" "unprognostic (9.81e-2)" "unprognostic (1.50e-1)" "unprognostic (8.43e-2)" "unprognostic (6.69e-2)" "unprognostic (6.31e-2)" "unprognostic (3.55e-3)" "unprognostic (4.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-2)" IL18 "IGIF, IL-18, IL-1g, IL1F4" ENSG00000150782 "Interleukin 18" Q14116 11 112143253-112164096 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 120.4;skin 1: 145.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 171.4;Basal squamous epithelial cells: 207.2;granulocytes: 198.7;Kupffer cells: 174.3;Macrophages: 154.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Liver - Kupffer cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003980, CAB007772" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted to blood" Interleukin NA Yes 196000 16000 "Cluster 29: Non-specific - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 58: Macrophages - Innate immune response" 2 "Nucleoplasm, Golgi apparatus" Cytosol "CAB007772: AB_562304, HPA003980: AB_1851670" "unprognostic (2.31e-3)" "unprognostic (3.25e-1)" "prognostic favorable (2.78e-4)" "unprognostic (3.41e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-1)" "unprognostic (1.65e-1)" "unprognostic (8.15e-2)" "unprognostic (3.23e-1)" "unprognostic (2.78e-1)" "unprognostic (1.96e-3)" "unprognostic (4.13e-1)" "unprognostic (3.58e-2)" "unprognostic (1.51e-1)" "unprognostic (3.19e-2)" "unprognostic (3.15e-2)" "unprognostic (9.01e-2)" IL18BP IL18BPa ENSG00000137496 "Interleukin 18 binding protein" O95998 11 71998613-72007315 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.2" "Cell type enhanced" "Detected in many" "Adipocytes: 13.0;Endothelial cells: 13.4;Exocrine glandular cells: 13.2;Langerhans cells: 16.1;Macrophages: 16.0;monocytes: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025980, HPA041061" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" "No annotated function" NA NA 3070000 16000000 "Cluster 25: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Endoplasmic reticulum" "CAB025980: , HPA041061: AB_2677280" "unprognostic (2.66e-3)" "unprognostic (2.04e-3)" "unprognostic (9.14e-3)" "unprognostic (1.70e-2)" "unprognostic (5.58e-3)" "unprognostic (7.75e-2)" "unprognostic (1.41e-1)" "unprognostic (6.20e-2)" "unprognostic (1.19e-2)" "unprognostic (1.75e-3)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.93e-6)" "unprognostic (1.19e-1)" "unprognostic (4.14e-2)" "unprognostic (6.76e-2)" "unprognostic (1.93e-2)" IL19 "IL-10C, IL-19, MDA1, NG.1, ZMDA1" ENSG00000142224 "Interleukin 19" Q9UHD0 1 206770764-206842981 "Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 19.2;salivary gland: 6.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 13.8;Ionocytes: 33.9;Rod photoreceptor cells: 6.5;Salivary duct cells: 8.7;Serous glandular cells: 9.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 172000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 35: Respiratory epithelial cells - Unknown function" "unprognostic (6.21e-2)" "unprognostic (3.84e-2)" "unprognostic (3.55e-1)" "unprognostic (2.17e-2)" "unprognostic (2.48e-5)" "unprognostic (1.07e-1)" "unprognostic (8.72e-3)" "unprognostic (8.42e-2)" "unprognostic (2.04e-3)" "unprognostic (9.17e-2)" "unprognostic (7.20e-2)" "unprognostic (4.91e-2)" "unprognostic (2.78e-1)" IL1A "IL-1A, IL1, IL1-ALPHA, IL1F1" ENSG00000115008 "Interleukin 1 alpha" P01583 2 112773925-112784493 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.9;testis: 10.1;urinary bladder: 25.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 36.7;Glandular and luminal cells: 28.2;Macrophages: 60.3;monocytes: 214.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.3;urothelial cancer: 17.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 98.6;head and neck cancer: 136.3" "Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" Interleukin NA NA 10800 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 5 "unprognostic (3.41e-2)" "prognostic unfavorable (9.52e-4)" "unprognostic (1.99e-2)" "unprognostic (4.28e-2)" "unprognostic (2.08e-1)" "unprognostic (8.03e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.62e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-3)" "unprognostic (1.22e-1)" "unprognostic (4.30e-3)" "prognostic unfavorable (4.03e-4)" "unprognostic (1.66e-1)" "unprognostic (2.44e-1)" "unprognostic (8.62e-2)" IL1B "IL-1B, IL1-BETA, IL1F2" ENSG00000125538 "Interleukin 1 beta" P01584 2 112829751-112836816 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 198.6;urinary bladder: 121.6" "Cell type enriched" "Detected in many" 5 "monocytes: 11738.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 94.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 177.9;Sarcoma: 319.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" Interleukin NA NA 2330 "Cluster 28: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 1 "unprognostic (1.55e-3)" "prognostic unfavorable (1.31e-4)" "unprognostic (2.75e-2)" "unprognostic (5.71e-2)" "unprognostic (1.34e-1)" "unprognostic (7.12e-2)" "unprognostic (2.63e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-1)" "unprognostic (3.63e-3)" "unprognostic (3.72e-2)" "unprognostic (5.57e-2)" "prognostic unfavorable (7.49e-5)" "unprognostic (1.29e-2)" "unprognostic (4.42e-2)" "unprognostic (5.09e-2)" "unprognostic (4.01e-2)" IL1F10 "FKSG75, IL-1F10, IL-1HY2, IL1-theta, MGC11983, MGC119832, MGC119833" ENSG00000136697 "Interleukin 1 family member 10" Q8WWZ1 2 113067970-113075843 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skin 1: 12.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 222000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" 1 "unprognostic (3.89e-1)" "unprognostic (6.25e-2)" "unprognostic (1.48e-1)" "unprognostic (1.18e-1)" "unprognostic (2.42e-2)" IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 303.4;Glandular and luminal cells: 312.5;Langerhans cells: 221.8;Mesothelial cells: 245.0;Prostatic glandular cells: 291.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 1400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 2 "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" IL1R2 "CD121b, IL1RB" ENSG00000115590 "Interleukin 1 receptor type 2" P27930 2 101991960-102028544 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 5 "Langerhans cells: 1470.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Region enhanced" "Detected in many" "cerebral cortex: 14.5" "Immune cell enriched" "Detected in some" 26 "neutrophil: 378.7" "Lineage enriched" "Detected in many" 26 "granulocytes: 378.7" "Cancer enhanced" "Detected in many" "lymphoma: 66.7" "Adipose visceral - Neutrophils, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Neutrophils" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027597, HPA027598" Uncertain "Secreted to blood" Receptor NA NA 7130000 27000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 28: Dendritic cells - Antigen presentation" 2 "HPA027597: AB_10600768, HPA027598: AB_10601229" "unprognostic (3.54e-2)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.83e-2)" "unprognostic (6.59e-2)" "unprognostic (1.42e-1)" "unprognostic (6.36e-2)" "unprognostic (4.82e-3)" "unprognostic (1.62e-2)" "unprognostic (7.15e-2)" "unprognostic (8.20e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.58e-12)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "unprognostic (1.77e-1)" "unprognostic (6.62e-2)" IL1RAP "C3orf13, IL-1RAcP, IL1R3" ENSG00000196083 "Interleukin 1 receptor accessory protein" Q9NPH3 3 190514051-190659750 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 218.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 125.7;Hepatocytes: 315.4;Oligodendrocyte precursor cells: 280.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 23.9;neutrophil: 95.8" "Lineage enriched" "Detected in many" 15 "granulocytes: 95.8" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035293 Uncertain Approved Vesicles,Cytosol "Secreted to blood" Receptor NA NA 350000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 43: Hepatocytes - Metabolism" 3 "Vesicles, Cytosol" "HPA035293: AB_10671511" "unprognostic (6.48e-2)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (8.84e-3)" "unprognostic (2.35e-2)" "unprognostic (6.60e-2)" "unprognostic (2.62e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.16e-7)" "unprognostic (4.02e-3)" "unprognostic (9.06e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.29e-4)" IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 59.9;kidney: 122.8;lung: 157.1;placenta: 193.2" "Cell type enriched" "Detected in many" 6 "granulocytes: 1024.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.4;eosinophil: 29.4" "Lineage enriched" "Detected in single" 73 "granulocytes: 38.4" "Cancer enhanced" "Detected in many" "Esophageal cancer: 24.0;pancreatic cancer: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" Receptor NA NA 19100000 3100000 "Cluster 41: Basophils - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 1 "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: AB_1079128, HPA007917: AB_1079129" "unprognostic (7.25e-2)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (5.28e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "unprognostic (2.07e-1)" "unprognostic (2.77e-1)" "unprognostic (4.50e-2)" "unprognostic (8.58e-2)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-3)" IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113099315-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1898.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 324.5;Hofbauer cells: 399.9;Langerhans cells: 377.6;Squamous epithelial cells: 526.1;Suprabasal keratinocytes: 1054.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "classical monocyte: 69.8;myeloid DC: 66.9;neutrophil: 257.2" "Group enriched" "Detected in many" 738 "dendritic cells: 66.9;granulocytes: 257.2;monocytes: 69.8" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 164.8" "Heart muscle - Neutrophils, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "HPA001482, CAB009633, CAB080340" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" "No annotated function" NA NA 291000 45000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Nucleoplasm, Cytosol" Centrosome "CAB009633: AB_2125576, CAB080340: , HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" IL2 "IL-2, TCGF" ENSG00000109471 "Interleukin 2" P60568 4 122451470-122456725 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Cytokine, Growth factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 9 "T-cells: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB010310 Uncertain "Secreted to blood" Interleukin NA NA 20300 "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "CAB010310: AB_649346" "unprognostic (8.87e-5)" "unprognostic (6.13e-3)" "unprognostic (1.38e-3)" "unprognostic (9.79e-3)" "unprognostic (2.56e-2)" "unprognostic (7.32e-2)" "unprognostic (2.06e-5)" "unprognostic (5.21e-3)" "unprognostic (8.01e-2)" IL20 "IL-20, IL10D, ZCYTO10" ENSG00000162891 "Interleukin 20" Q9NYY1 1 206865623-206869223 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.7;skin 1: 1.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 41.7;Basal prostatic cells: 29.6;Basal respiratory cells: 14.0;Granulosa cells: 20.8;Langerhans cells: 18.8;Salivary duct cells: 16.5;Suprabasal keratinocytes: 11.6" "Cancer enhanced" "Detected in some" "breast cancer: 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 13 "breast cancer: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" CAB025802 Uncertain "Secreted to blood" Interleukin NA NA 109000 "Cluster 21: Testis - Unknown function" "Cluster 27: Breast cancer - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" "CAB025802: " "unprognostic (3.08e-2)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (1.16e-2)" "unprognostic (6.45e-2)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (3.46e-1)" "unprognostic (1.60e-1)" "unprognostic (3.38e-2)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" IL21 "IL-21, Za11" ENSG00000138684 "Interleukin 21" Q9HBE4 4 122610108-122621066 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "lymphoid tissue: 5.8" "Group enriched" "Detected in some" 8 "Early spermatids: 18.7;Late spermatids: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 55700 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 11: Late spermatids - Unknown function" "unprognostic (2.42e-1)" "unprognostic (2.12e-1)" "unprognostic (6.80e-2)" IL22 "IL-21, IL-22, IL-D110, IL-TIF, ILTIF, MGC79382, MGC79384, TIFa, TIFIL-23, zcyto18" ENSG00000127318 "Interleukin 22" Q9GZX6 12 68248242-68253604 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.5" "Cell type enriched" "Detected in some" 4 "T-cells: 35.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.7" "Region enriched" "Detected in some" 20 "cerebellum: 19.7" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 86900 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "unprognostic (2.57e-1)" "unprognostic (4.24e-2)" IL22RA2 "CRF2-S1, IL-22BP" ENSG00000164485 "Interleukin 22 receptor subunit alpha 2" Q969J5 6 137143820-137173648 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "breast: 3.5;lymphoid tissue: 3.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.7;Breast myoepithelial cells: 3.5;Macrophages: 1.1;Syncytiotrophoblasts: 1.9" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030582, CAB034906" Uncertain "Secreted to blood" Receptor NA NA 40500000 "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 17: Breast glandular cells - Lactation" "CAB034906: AB_2124501, HPA030582: AB_10600716" "unprognostic (1.09e-1)" "unprognostic (7.97e-4)" "unprognostic (1.32e-3)" "unprognostic (1.24e-2)" "unprognostic (4.03e-3)" "unprognostic (1.11e-1)" "unprognostic (4.51e-1)" "unprognostic (1.92e-1)" "unprognostic (1.07e-1)" "unprognostic (1.10e-1)" "unprognostic (7.58e-2)" "unprognostic (1.32e-1)" "unprognostic (1.62e-1)" "unprognostic (6.61e-2)" IL23A "IL-23, IL-23A, IL23P19, P19, SGRF" ENSG00000110944 "Interleukin 23 subunit alpha" Q9NPF7 12 56334174-56340410 "FDA approved drug targets, Predicted secreted proteins" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Tissue remodeling" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "urinary bladder: 42.8" "Cell type enriched" "Detected in many" 4 "Langerhans cells: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "MAIT T-cell: 14.2;memory B-cell: 19.0;memory CD4 T-cell: 25.8;memory CD8 T-cell: 12.5;naive B-cell: 21.6;naive CD4 T-cell: 28.2;naive CD8 T-cell: 17.7;T-reg: 15.6" "Group enriched" "Detected in many" 12 "B-cells: 21.6;T-cells: 28.2" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Region enhanced" "Detected in some" "white matter: 3.9" "Not detected" "Not detected" HPA001554 Approved Approved Cytosol "Secreted to blood" Interleukin NA NA 11000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 Cytosol "HPA001554: AB_1079135" "unprognostic (2.34e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" "unprognostic (1.06e-1)" "unprognostic (5.24e-2)" "unprognostic (4.01e-3)" "unprognostic (4.40e-1)" "unprognostic (1.43e-3)" "unprognostic (1.30e-1)" "unprognostic (6.79e-2)" "unprognostic (3.38e-2)" "unprognostic (4.16e-2)" "unprognostic (3.03e-10)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.83e-1)" "unprognostic (4.50e-3)" IL24 "C49A, FISP, IL-24, IL10B, mda-7, Mob-5, ST16" ENSG00000162892 "Interleukin 24" Q13007 1 206897443-206904139 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 14.8;lymphoid tissue: 24.9;urinary bladder: 14.0" "Cell type enhanced" "Detected in some" "B-cells: 1.9;Basal keratinocytes: 5.3;Macrophages: 2.1;Mesothelial cells: 1.5;Pancreatic endocrine cells: 3.4;Smooth muscle cells: 1.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 9.9" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 10 "B-cells: 5.4;T-cells: 3.7" "Cancer enriched" "Detected in many" 5 "skin cancer: 86.0" "Not detected" "Not detected" "Not detected" "Not detected" CAB025972 Uncertain "Secreted to blood" Interleukin NA NA 140000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 47: Spleen - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 4 "CAB025972: " "prognostic favorable (5.09e-4)" "unprognostic (3.79e-1)" "unprognostic (2.89e-2)" "unprognostic (4.09e-3)" "unprognostic (3.98e-1)" "unprognostic (2.68e-1)" "unprognostic (2.85e-2)" "unprognostic (2.20e-2)" "unprognostic (3.98e-1)" "unprognostic (3.35e-2)" "unprognostic (8.04e-2)" "unprognostic (7.63e-2)" "unprognostic (3.43e-4)" "unprognostic (5.41e-2)" "unprognostic (1.29e-1)" "unprognostic (7.91e-2)" "unprognostic (3.33e-2)" IL25 "IL-17E, IL-25, IL17E" ENSG00000166090 "Interleukin 25" Q9H293 14 23372809-23376403 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB024864 Uncertain "Secreted to blood" Interleukin NA NA 35000 "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "CAB024864: " "unprognostic (1.49e-1)" "unprognostic (6.82e-2)" IL26 "AK155, IL-26" ENSG00000111536 "Interleukin 26" Q9NPH9 12 68201349-68225810 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.5;Mesothelial cells: 1.2;T-cells: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "lymphoma: 29.4" "Low region specificity" "Detected in all" HPA077990 Approved "Golgi apparatus,Vesicles" "Secreted to blood" Interleukin NA NA 35700 "Cluster 71: Lymphoma - Inflammatory response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Golgi apparatus, Vesicles" "HPA077990: " "unprognostic (2.71e-1)" "unprognostic (8.87e-2)" "unprognostic (3.26e-5)" "unprognostic (7.10e-2)" "unprognostic (5.90e-2)" "unprognostic (2.96e-1)" "unprognostic (3.69e-5)" "unprognostic (3.80e-1)" "unprognostic (5.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.79e-2)" IL27 "IL-27, IL-27A, IL27A, IL27p28, IL30, MGC71873, p28" ENSG00000197272 "Interleukin 27" Q8NEV9 16 28499362-28512051 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antiviral protein, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 26.1" "Group enriched" "Detected in some" 6 "Hepatocytes: 16.5;Syncytiotrophoblasts: 31.1" "Cancer enriched" "Detected in some" 8 "liver cancer: 4.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.6;intermediate monocyte: 3.8" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB024722 Approved "Secreted to blood" Interleukin NA NA 521000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "CAB024722: " "unprognostic (4.79e-3)" "unprognostic (2.66e-3)" "unprognostic (4.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.09e-1)" "unprognostic (6.55e-3)" "prognostic favorable (1.30e-4)" "unprognostic (3.76e-2)" "unprognostic (8.23e-3)" "unprognostic (1.29e-2)" "unprognostic (6.07e-3)" "unprognostic (4.57e-2)" "unprognostic (2.41e-7)" "unprognostic (6.44e-2)" "unprognostic (1.04e-3)" "unprognostic (2.13e-1)" "unprognostic (2.83e-2)" IL3 "IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF" ENSG00000164399 "Interleukin 3" P08700 5 132060655-132063204 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 17800 "Cluster 9: Non-specific - Receptor signaling" "Cluster 49: HMC-1 - Innate immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "unprognostic (9.74e-2)" IL31 IL-31 ENSG00000204671 "Interleukin 31" Q6EBC2 12 122172029-122174221 "Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" CAB025657 Uncertain "Secreted to blood" Interleukin NA NA 37800 "Cluster 50: Lymphoma - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "CAB025657: " "unprognostic (1.70e-1)" IL32 "NK4, TAIF, TAIFb, TAIFd" ENSG00000008517 "Interleukin 32" P24001 16 3065297-3082192 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 808.7;pancreas: 654.9" "Cell type enhanced" "Detected in many" "Ductal cells: 1395.6;Exocrine glandular cells: 3125.9;Pancreatic endocrine cells: 3246.5;Proximal enterocytes: 4806.7;Proximal tubular cells: 5236.5;T-cells: 1635.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 4640.3" "Lineage enriched" "Detected in all" 8 "T-cells: 4640.3" "Cancer enhanced" "Detected in all" "Kidney cancer: 674.0" "HPA029397, CAB030029" Uncertain "Secreted to blood" Interleukin NA NA 46100 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Non-specific - Mixed function" "CAB030029: AB_1089175, HPA029397: AB_10612120" "unprognostic (2.00e-2)" "unprognostic (2.89e-2)" "unprognostic (2.86e-1)" "prognostic favorable (1.33e-4)" "unprognostic (2.95e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-2)" "unprognostic (2.58e-2)" "unprognostic (1.73e-3)" "unprognostic (2.19e-2)" "unprognostic (3.32e-3)" "unprognostic (3.51e-1)" "unprognostic (3.30e-2)" "unprognostic (8.08e-2)" "unprognostic (3.86e-2)" "unprognostic (3.16e-2)" "unprognostic (4.29e-3)" IL33 "C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV" ENSG00000137033 "Interleukin 33" O95760 9 6215786-6257983 "Predicted intracellular proteins, Predicted secreted proteins" Transcription Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 118.2" "Cell type enhanced" "Detected in many" "Adipocytes: 73.0;Basal respiratory cells: 69.3;Endothelial cells: 155.2;Fibroblasts: 89.8;Gastric mucus-secreting cells: 47.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "colorectal cancer: 24.6;Rhabdoid: 15.7;Sarcoma: 26.2;thyroid cancer: 8.9" "Heart muscle - Fibroblasts, Liver - Vascular Endothelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007057, HPA022899, HPA024426" Supported Supported Nucleoplasm,Vesicles "Secreted to blood" Interleukin NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 5 Nucleoplasm Vesicles "CAB007057: , HPA022899: , HPA024426: AB_1845820" "prognostic favorable (4.42e-4)" "unprognostic (8.36e-2)" "unprognostic (5.67e-3)" "unprognostic (7.67e-3)" "unprognostic (4.27e-1)" "unprognostic (1.63e-1)" "unprognostic (2.59e-3)" "unprognostic (2.66e-3)" "unprognostic (3.18e-1)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (8.08e-2)" "unprognostic (1.58e-3)" "unprognostic (4.70e-3)" "unprognostic (4.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.85e-3)" IL34 "C16orf77, IL-34, MGC34647" ENSG00000157368 "Interleukin 34" Q6ZMJ4 16 70579895-70660682 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 103.8;skin 1: 60.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 17.8;Leydig cells: 18.2;Melanocytes: 18.9;Muller glia cells: 23.0;Peritubular cells: 41.0;Schwann cells: 39.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 13 "eosinophil: 18.6" "Lineage enriched" "Detected in single" 187 "granulocytes: 18.6" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Skin - Keratinocyte (other), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Interleukin NA NA 57100 "Cluster 22: Eosinophils - Transcription" "Cluster 47: Spleen - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 1 "unprognostic (3.76e-3)" "prognostic favorable (7.41e-4)" "unprognostic (5.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.27e-2)" "prognostic favorable (9.69e-4)" "unprognostic (8.19e-2)" "unprognostic (1.59e-3)" "unprognostic (3.83e-2)" "unprognostic (6.11e-3)" "unprognostic (3.18e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (3.52e-8)" "unprognostic (6.47e-3)" "unprognostic (4.58e-2)" "unprognostic (5.83e-2)" "unprognostic (4.37e-2)" IL36A "FIL1, FIL1E, IL-1F6, IL1(EPSILON), IL1F6, MGC129552, MGC129553" ENSG00000136694 "Interleukin 36 alpha" Q9UHA7 2 113005459-113008044 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "esophagus: 397.4;lymphoid tissue: 112.2" "Cell type enhanced" "Detected in some" "Serous glandular cells: 2.2;Suprabasal keratinocytes: 1.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 8.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.2" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 249000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 59: Suprabasal keratinocytes - Cornification" "unprognostic (1.37e-1)" "unprognostic (9.66e-3)" "unprognostic (5.46e-1)" IL36B "FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882" ENSG00000136696 "Interleukin 36 beta" Q9NZH7 2 113022089-113052867 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 2.1;lymphoid tissue: 3.7;skin 1: 7.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 1.6;Brain cancer: 3.0" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA035664 Uncertain "Secreted to blood" Interleukin NA NA 8560 "Cluster 13: Skin - Cornification" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Late spermatids - Unknown function" "HPA035664: AB_10669672" "unprognostic (8.45e-2)" "unprognostic (1.62e-1)" "unprognostic (3.56e-2)" "unprognostic (1.06e-1)" "unprognostic (3.77e-2)" "unprognostic (2.40e-3)" "unprognostic (2.05e-1)" "unprognostic (7.10e-3)" IL36G "IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1" ENSG00000136688 "Interleukin 36 gamma" Q9NZH8 2 112973203-112985658 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 13.9;lymphoid tissue: 38.3;skin 1: 30.3" "Group enriched" "Detected in some" 5 "Basal respiratory cells: 132.5;Ionocytes: 47.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 36.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gallbladder cancer: 50.3;head and neck cancer: 17.3" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA068168 Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Interleukin NA NA 37100 11000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA068168: " "unprognostic (1.56e-2)" "unprognostic (2.88e-1)" "unprognostic (7.27e-2)" "unprognostic (3.15e-2)" "unprognostic (4.91e-2)" "unprognostic (1.92e-1)" "unprognostic (3.68e-1)" "unprognostic (3.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (5.79e-2)" "unprognostic (5.58e-2)" "unprognostic (1.06e-1)" IL36RN "FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840" ENSG00000136695 "Interleukin 36 receptor antagonist" Q9UBH0 2 113058638-113065382 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 25.8;lymphoid tissue: 43.8;skin 1: 58.4" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 9.0;Suprabasal keratinocytes: 9.3;Syncytiotrophoblasts: 4.3" "Cancer enriched" "Detected in some" 7 "head and neck cancer: 25.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.6" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 107000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 11 "unprognostic (3.88e-3)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (4.29e-1)" "unprognostic (8.68e-3)" "unprognostic (9.80e-2)" "unprognostic (2.48e-1)" "unprognostic (5.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" "unprognostic (5.37e-2)" "unprognostic (3.85e-3)" "unprognostic (4.23e-3)" IL37 "FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7" ENSG00000125571 "Interleukin 37" Q9NZH6 2 112911165-112918882 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 117.8" "Cell type enriched" "Detected in some" 5 "Ionocytes: 18.0" "Cancer enriched" "Detected in some" 6 "lung cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.5" "Skin - Keratinocyte (granular)" "HPA054371, HPA057950" Uncertain Supported Nucleoplasm,Vesicles "Secreted to blood" Interleukin NA NA 76700 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 6 Nucleoplasm Vesicles "HPA054371: AB_2682465, HPA057950: AB_2683561" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.71e-5)" "unprognostic (1.11e-1)" "unprognostic (2.58e-2)" "unprognostic (1.09e-2)" "unprognostic (1.28e-2)" "unprognostic (9.54e-2)" "unprognostic (8.26e-3)" "unprognostic (3.95e-2)" "unprognostic (1.66e-1)" "unprognostic (8.92e-2)" "unprognostic (1.35e-2)" IL4 "BCGF-1, BCGF1, BSF1, IL-4, MGC79402" ENSG00000113520 "Interleukin 4" P05112 5 132673986-132682678 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "B-cell activation" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "T-cells: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 862 "basophil: 476.8" "Lineage enriched" "Detected in single" 862 "granulocytes: 476.8" "Cancer enhanced" "Detected in single" "lymphoma: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA072995, CAB078477" Approved "Secreted to blood" Interleukin NA NA 13600 "Cluster 46: Basophils - Proteolysis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 50: Lymphoma - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 "CAB078477: AB_417057, HPA072995: AB_2732215" "unprognostic (3.40e-2)" "unprognostic (9.19e-2)" "unprognostic (1.41e-1)" "unprognostic (2.49e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.69e-1)" "unprognostic (7.33e-2)" "unprognostic (2.26e-2)" "unprognostic (1.96e-1)" "unprognostic (1.47e-10)" "unprognostic (9.21e-3)" "unprognostic (2.88e-1)" "unprognostic (4.93e-2)" "unprognostic (1.24e-2)" IL4I1 FIG1 ENSG00000104951 "Interleukin 4 induced 1" Q96RQ9 19 49889654-49929539 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 17.6;testis: 26.0" "Cell type enhanced" "Detected in many" "Early spermatids: 96.0;Hofbauer cells: 92.7;Langerhans cells: 456.0;Secretory cells: 135.5" "Cancer enhanced" "Detected in all" "ovarian cancer: 35.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 103.5" "Group enriched" "Detected in many" 6 "monocytes: 36.6;T-cells: 103.5" "Cancer enhanced" "Detected in many" "lymphoma: 33.1;Myeloma: 18.6" "Breast - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045598 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" Immunity NA NA "Cluster 1: T-cells - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 50: Lymphoma - Unknown function" "Cluster 14: Langerhans cells - Innate immune response" 2 "Nucleoplasm, Cytosol" "HPA045598: AB_10969138" "unprognostic (6.23e-2)" "unprognostic (1.32e-2)" "unprognostic (8.39e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.61e-2)" "unprognostic (3.74e-3)" "unprognostic (7.03e-2)" "unprognostic (2.52e-2)" "unprognostic (3.84e-3)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.23e-10)" "unprognostic (2.10e-1)" "unprognostic (1.01e-1)" "unprognostic (6.44e-2)" "unprognostic (2.11e-3)" IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 71.7;granulocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 77.1" "Group enriched" "Detected in all" 5 "B-cells: 77.1;granulocytes: 31.1" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 139.2" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" Receptor NA NA 38500 110000 "Cluster 34: B-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Neutrophils - Degranulation" 3 "Plasma membrane" "Nucleoplasm, Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" IL5 "EDF, IL-5, TRF" ENSG00000113525 "Interleukin 5" P05113 5 132541445-132556838 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 4.9" "Group enriched" "Detected in some" 9 "granulocytes: 6.7;Spermatocytes: 17.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "memory B-cell: 1.4" "Lineage enriched" "Detected in single" 8 "B-cells: 1.4" "Cancer enriched" "Detected in single" 4 "lymphoma: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB010304 Approved "Secreted to blood" Interleukin NA NA 4130 "Cluster 46: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 59: Leukemia - T-cell receptor" "Cluster 31: Spermatocytes - Spermatogenesis" 2 "CAB010304: AB_2296159" "unprognostic (1.66e-1)" "unprognostic (4.76e-2)" "unprognostic (5.30e-3)" "unprognostic (2.35e-1)" "unprognostic (9.07e-2)" "unprognostic (7.98e-2)" "unprognostic (2.03e-2)" "unprognostic (3.51e-2)" "unprognostic (1.97e-1)" "unprognostic (1.44e-2)" "unprognostic (1.53e-1)" "unprognostic (2.09e-1)" "unprognostic (5.27e-2)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" IL5RA "CD125, CDw125, IL5R" ENSG00000091181 "Interleukin 5 receptor subunit alpha" Q01344 3 3066324-3126613 "CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 6.0;fallopian tube: 10.4" "Group enriched" "Detected in some" 5 "Ciliated cells: 31.3;granulocytes: 34.5;Plasma cells: 16.6" "Cancer enhanced" "Detected in some" "prostate cancer: 1.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 190 "basophil: 179.4;eosinophil: 356.1" "Lineage enriched" "Detected in many" 253 "granulocytes: 356.1" "Cancer enhanced" "Detected in some" "lymphoma: 2.7;Myeloma: 8.5" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Mast cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" Receptor NA NA 910000 "Cluster 22: Eosinophils - Transcription" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 50: Lymphoma - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" 3 "unprognostic (1.38e-3)" "unprognostic (2.26e-2)" "unprognostic (2.66e-1)" "unprognostic (6.13e-3)" "unprognostic (2.66e-1)" "unprognostic (1.54e-3)" "unprognostic (7.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.83e-1)" "unprognostic (1.67e-1)" "unprognostic (9.84e-4)" "unprognostic (4.32e-3)" "unprognostic (3.08e-2)" "unprognostic (6.95e-2)" "unprognostic (2.20e-1)" "unprognostic (7.49e-2)" "unprognostic (4.93e-2)" IL6 "BSF2, HGF, HSF, IFNB2, IL-6" ENSG00000136244 "Interleukin 6" P05231 7 22725884-22732002 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 210.6;urinary bladder: 265.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 239.2;Fibroblasts: 109.1;Glandular and luminal cells: 328.1;monocytes: 160.7;Smooth muscle cells: 310.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 15.1" "Group enriched" "Detected in some" 47 "memory B-cell: 4.1;naive B-cell: 5.2" "Lineage enriched" "Detected in single" 52 "B-cells: 5.2" "Cancer enhanced" "Detected in many" "Kidney cancer: 219.1" "Colon - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB023406, CAB072821" Supported Approved Vesicles "Secreted to blood" "Acute phase" NA NA 5700 "Cluster 14: Non-specific - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Smooth muscle cells - Signal transduction" 5 Vesicles "CAB023406: AB_617317, CAB072821: " "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (3.59e-2)" "unprognostic (9.88e-3)" "unprognostic (1.35e-1)" "unprognostic (3.07e-3)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.10e-11)" "unprognostic (2.45e-3)" "unprognostic (2.10e-1)" "unprognostic (4.31e-2)" "unprognostic (7.80e-2)" IL6R "CD126, gp80, IL-1Ra, IL-6R, IL6RA" ENSG00000160712 "Interleukin 6 receptor" P08887 1 154405193-154469450 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.9;skeletal muscle: 90.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 86.2;Langerhans cells: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 89.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 83.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" Receptor NA NA 24800000 35000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" 3 "unprognostic (1.19e-1)" "unprognostic (3.97e-1)" "unprognostic (1.19e-1)" "unprognostic (1.08e-1)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-2)" "unprognostic (3.27e-1)" "unprognostic (6.42e-2)" "prognostic favorable (1.65e-4)" "unprognostic (7.94e-2)" "unprognostic (1.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.51e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" IL6ST "CD130, GP130, IL-6RB, sGP130" ENSG00000134352 "Interleukin 6 cytokine family signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 689.8;Mesothelial cells: 413.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 22.8" "Lineage enriched" "Detected in many" 5 "T-cells: 22.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" Receptor NA NA 160000000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Liver - Plasma proteins" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 8 "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: AB_1078439" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (3.95e-2)" "unprognostic (8.93e-2)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (9.53e-3)" "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (3.69e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" IL7 IL-7 ENSG00000104432 "Interleukin 7" P13232 8 78675743-78805523 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 118.9;Late spermatids: 146.6;Lymphatic endothelial cells: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.8;naive B-cell: 8.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA019590 Approved "Secreted to blood" Interleukin NA NA 60700 "Cluster 32: Basophils - Transcription" "Cluster 25: Small intestine - Absorption" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 36: Late spermatids - Unknown function" 1 "HPA019590: AB_10794621" "unprognostic (3.19e-3)" "unprognostic (1.44e-1)" "unprognostic (9.57e-3)" "unprognostic (5.45e-2)" "unprognostic (9.37e-3)" "unprognostic (3.36e-1)" "unprognostic (1.71e-1)" "unprognostic (1.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (6.55e-2)" "unprognostic (2.11e-4)" IL7R "CD127, IL7RA, lnc-IL7R" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 178.8" "Cell type enriched" "Detected in many" 6 "T-cells: 1368.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 102.3;MAIT T-cell: 370.2;memory CD4 T-cell: 214.4;memory CD8 T-cell: 151.1;naive CD4 T-cell: 180.0;naive CD8 T-cell: 125.1;NK-cell: 113.4" "Group enriched" "Detected in all" 34 "NK-cells: 113.4;T-cells: 370.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Colon - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 610000 "Cluster 27: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 10 "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" IL9 "HP40, IL-9, P40" ENSG00000145839 "Interleukin 9" P15248 5 135892246-135895841 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "lymphoma: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 11000 "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" IL9R CD129 ENSG00000124334 "Interleukin 9 receptor" Q01113 X 155997696-156010817 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.3;urinary bladder: 4.1" "Cell type enhanced" "Detected in some" "granulocytes: 1.7;T-cells: 2.3" "Group enriched" "Detected in some" 4 "cervical cancer: 0.7;urothelial cancer: 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 3.5" "Group enriched" "Detected in many" 23 "B-cells: 1.9;granulocytes: 3.5;T-cells: 1.4" "Group enriched" "Detected in some" 7 "Leukemia: 18.3;lymphoma: 14.4" "Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063240, HPA064557" Approved "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 1 "HPA063240: AB_2732700, HPA064557: AB_2732716" "unprognostic (1.07e-2)" "unprognostic (3.27e-3)" "unprognostic (9.52e-3)" "unprognostic (4.13e-2)" "unprognostic (7.35e-2)" "unprognostic (3.26e-4)" "unprognostic (8.94e-2)" "unprognostic (3.56e-2)" "unprognostic (2.01e-1)" "unprognostic (1.82e-1)" "unprognostic (2.90e-2)" "unprognostic (2.04e-1)" "unprognostic (3.98e-8)" "unprognostic (2.06e-1)" "unprognostic (2.38e-1)" "unprognostic (4.07e-1)" "prognostic favorable (1.90e-7)" ILDR1 "DFNB42, MGC50831" ENSG00000145103 "Immunoglobulin like domain containing receptor 1" Q86SU0 3 121987323-122022247 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 15.2" "Cell type enhanced" "Detected in many" "Club cells: 13.5;Collecting duct cells: 11.7;Cytotrophoblasts: 15.6;Distal enterocytes: 18.2;Glandular and luminal cells: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 4 "B-cells: 1.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 12.4" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA018207 Approved "Intracellular and membrane" Receptor NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA018207: AB_1851742" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (9.24e-2)" "unprognostic (4.46e-3)" "unprognostic (9.73e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-2)" "unprognostic (2.80e-2)" "unprognostic (2.00e-1)" "unprognostic (2.04e-1)" "unprognostic (7.78e-2)" "unprognostic (2.37e-1)" "prognostic favorable (5.79e-9)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (3.25e-3)" "unprognostic (2.21e-2)" IMPG1 "GP147, IPM150, SPACR" ENSG00000112706 "Interphotoreceptor matrix proteoglycan 1" Q17R60 6 75921114-76072678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 99 "retina: 650.2" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 863.2;Rod photoreceptor cells: 635.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 2.0" "Region enriched" "Detected in single" 4 "basal ganglia: 3.3" "Low region specificity" "Detected in many" "HPA027142, HPA030332, HPA030333" Enhanced "Secreted in other tissues" Receptor NA NA "Cluster 76: Retina - Visual perception" "Cluster 34: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA027142: AB_2672132, HPA030332: AB_2673432, HPA030333: AB_2673433" "unprognostic (6.65e-2)" "unprognostic (4.13e-2)" "unprognostic (1.20e-1)" "unprognostic (8.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.49e-3)" "unprognostic (5.97e-2)" "unprognostic (3.56e-3)" "unprognostic (1.89e-2)" "unprognostic (2.20e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-3)" "unprognostic (2.84e-1)" "unprognostic (1.73e-2)" "unprognostic (2.09e-1)" "unprognostic (6.01e-2)" "unprognostic (1.96e-2)" IMPG2 "IPM200, RP56, SPACRCAN" ENSG00000081148 "Interphotoreceptor matrix proteoglycan 2" Q9BZV3 3 101222546-101320575 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "retina: 296.1" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 640.6;Rod photoreceptor cells: 334.9" "Cancer enriched" "Detected in single" 12 "ovarian cancer: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Brain cancer: 2.3;lung cancer: 1.2;ovarian cancer: 2.2;Uterine cancer: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008779, HPA015907" Enhanced "Secreted in other tissues" Receptor NA NA "Cluster 76: Retina - Visual perception" "Cluster 44: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA008779: AB_2668138, HPA015907: AB_2669323" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.40e-1)" "unprognostic (9.58e-3)" "unprognostic (1.28e-1)" "unprognostic (4.80e-5)" "unprognostic (6.66e-4)" "unprognostic (1.85e-1)" "unprognostic (1.09e-1)" "unprognostic (6.59e-2)" "unprognostic (7.51e-3)" "unprognostic (1.28e-1)" "unprognostic (4.50e-9)" "unprognostic (7.12e-2)" "unprognostic (2.70e-1)" "unprognostic (2.81e-2)" "unprognostic (6.08e-2)" INHA ENSG00000123999 "Inhibin subunit alpha" P05111 2 219569162-219575711 "Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 73.2;ovary: 101.1;testis: 92.6" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 41.5;Granulosa cells: 120.5;Ovarian stromal cells: 59.5;Sertoli cells: 111.5;Syncytiotrophoblasts: 334.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB000047, HPA019141, HPA048834" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" Hormone NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 Vesicles "Golgi apparatus" "CAB000047: AB_322161, HPA019141: AB_1851789, HPA048834: " "unprognostic (8.90e-3)" "unprognostic (2.91e-2)" "unprognostic (2.82e-1)" "unprognostic (7.55e-2)" "unprognostic (1.02e-3)" "unprognostic (1.45e-1)" "unprognostic (3.57e-1)" "unprognostic (9.61e-3)" "unprognostic (4.15e-3)" "unprognostic (6.71e-2)" "unprognostic (3.73e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (4.03e-5)" "unprognostic (4.85e-2)" "unprognostic (7.20e-2)" "unprognostic (1.93e-1)" "unprognostic (4.43e-2)" INHBA ENSG00000122641 "Inhibin subunit beta A" P08476 7 41667168-41705834 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 20.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 97.9;Langerhans cells: 89.3;Leydig cells: 148.8;Macrophages: 84.9;Pancreatic endocrine cells: 336.2;Syncytiotrophoblasts: 178.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 141.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" Hormone NA NA 210000 "Cluster 62: Connective tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" "unprognostic (4.11e-3)" "prognostic unfavorable (1.46e-5)" "unprognostic (4.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.18e-2)" "prognostic unfavorable (4.34e-4)" "unprognostic (2.05e-2)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.44e-1)" "unprognostic (1.31e-1)" "unprognostic (1.23e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (7.91e-8)" "unprognostic (6.22e-3)" "unprognostic (1.11e-2)" "unprognostic (3.25e-2)" "unprognostic (3.18e-3)" INHBB ENSG00000163083 "Inhibin subunit beta B" P09529 2 120346136-120351803 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 50.8;breast: 41.9" "Cell type enriched" "Detected in many" 4 "Adipocytes: 199.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 44.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 49.5" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079405 Approved Vesicles "Secreted to blood" Hormone NA NA 130000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Vesicles "HPA079405: " "unprognostic (7.80e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.26e-2)" "unprognostic (4.26e-2)" "unprognostic (3.61e-3)" "unprognostic (2.13e-2)" "unprognostic (5.52e-2)" "unprognostic (6.99e-2)" "unprognostic (3.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.57e-3)" "unprognostic (4.14e-1)" "prognostic favorable (1.02e-4)" "unprognostic (1.76e-2)" INHBC ENSG00000175189 "Inhibin subunit beta C" P55103 12 57434784-57452062 "Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 171 "liver: 159.9" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 44.4" "Cancer enriched" "Detected in single" 85 "liver cancer: 22.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 4.9" "Liver - Hepatocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050755 Approved Cytosol "Secreted to blood" Hormone NA NA 21000000 "Cluster 31: Liver - Plasma proteins" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 62: Hepatocytes - Metabolism" Cytosol "HPA050755: " "unprognostic (5.26e-2)" "unprognostic (4.58e-1)" "unprognostic (3.43e-3)" "unprognostic (4.08e-3)" "unprognostic (3.76e-1)" "unprognostic (1.98e-2)" "unprognostic (1.03e-2)" "unprognostic (1.10e-1)" "unprognostic (1.34e-1)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.68e-4)" "unprognostic (2.90e-2)" "unprognostic (1.52e-1)" "unprognostic (3.55e-3)" "unprognostic (5.05e-2)" INHBE "activin, MGC4638" ENSG00000139269 "Inhibin subunit beta E" P58166 12 57452323-57459280 "Plasma proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 96 "liver: 144.2" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 33.4" "Cancer enriched" "Detected in some" 27 "liver cancer: 34.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Myeloma: 76.4" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016843, CAB034017" Enhanced Supported Vesicles "Secreted to blood" Hormone NA NA 3500000 "Cluster 31: Liver - Plasma proteins" "Cluster 35: Non-specific - DNA binding" "Cluster 13: Non-specific - Mixed function" "Cluster 62: Hepatocytes - Metabolism" Vesicles "CAB034017: AB_2233745, HPA016843: AB_1851796" "unprognostic (7.34e-2)" "unprognostic (6.73e-2)" "unprognostic (3.45e-1)" "unprognostic (4.69e-5)" "unprognostic (2.61e-1)" "unprognostic (2.50e-1)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.79e-3)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.66e-8)" "unprognostic (4.09e-3)" "unprognostic (1.56e-1)" "unprognostic (3.57e-2)" "unprognostic (7.52e-3)" INPP5A 5PTASE ENSG00000068383 "Inositol polyphosphate-5-phosphatase A" Q14642 10 132537787-132783480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 6.7" "Lineage enriched" "Detected in single" 29 "granulocytes: 6.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Region enhanced" "Detected in all" "cerebellum: 250.8" "Low region specificity" "Detected in all" HPA012285 Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 Cytosol "Plasma membrane" "HPA012285: AB_1851802" "prognostic unfavorable (7.47e-4)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (1.68e-3)" "unprognostic (1.43e-1)" "unprognostic (3.25e-2)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (5.65e-2)" "unprognostic (4.35e-1)" "unprognostic (4.70e-2)" "unprognostic (1.70e-2)" "prognostic favorable (3.15e-4)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (8.91e-3)" "unprognostic (8.66e-2)" INS "IDDM1, IDDM2" ENSG00000254647 Insulin P01308 11 2159779-2161221 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism" Hormone "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 134 "pancreas: 12517.5" "Cell type enriched" "Detected in some" 1284 "Pancreatic endocrine cells: 46354.5" "Cancer enriched" "Detected in single" 7165 "pancreatic cancer: 1751.3" "Region enhanced" "Detected in single" "pons: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bone cancer: 8.4;ovarian cancer: 2.2" "Pancreas - Beta cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 13 "midbrain: 1.7" "CAB000048, HPA004932, CAB012098, CAB053843" Enhanced "Secreted to blood" Hormone NA NA 437000 "Cluster 15: Pancreas - Proteolysis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 20: Enteroendocrine cells - Hormone signaling" 4 "CAB000048: , CAB012098: AB_300968, CAB053843: AB_620123, HPA004932: AB_1851816" "unprognostic (7.61e-2)" INS-IGF2 ENSG00000129965 "INS-IGF2 readthrough" F8WCM5 11 2132538-2161209 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 1.6;Sarcoma: 1.3" "Liver - Hepatocytes, Pancreas - Beta cells" "CAB019430, HPA071234" Enhanced Uncertain Nucleoplasm "Secreted to digestive system" "No annotated function" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 33: Sarcoma - Muscle contraction" Nucleoplasm "CAB019430: AB_10691857, HPA071234: " "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" INSL3 "MGC119818, MGC119819, RLF, RLNL" ENSG00000248099 "Insulin like 3" P51460 19 17816512-17821574 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 51 "ovary: 124.5;testis: 397.1" "Group enriched" "Detected in some" 12 "Leydig cells: 1245.8;Peritubular cells: 979.3" "Cancer enriched" "Detected in many" 21 "testis cancer: 39.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.5" "Testis - Leydig cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA028615 Enhanced "Secreted to blood" Hormone NA NA 566000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 15: Non-specific - Transcription" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" 1 "HPA028615: AB_10600717" "unprognostic (3.25e-1)" "unprognostic (2.25e-4)" "unprognostic (3.50e-5)" "unprognostic (7.04e-2)" "unprognostic (1.74e-4)" "unprognostic (4.60e-2)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (4.46e-1)" "unprognostic (4.93e-2)" "unprognostic (9.51e-10)" "unprognostic (6.80e-3)" "unprognostic (1.41e-1)" "unprognostic (8.85e-2)" "unprognostic (1.09e-5)" INSL4 EPIL ENSG00000120211 "Insulin like 4" Q14641 9 5231419-5235304 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "placenta: 15.4" "Cell type enriched" "Detected in some" 14 "Syncytiotrophoblasts: 4375.5" "Cancer enhanced" "Detected in some" "lung cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.0" HPA065145 Approved Vesicles "Secreted to blood" Hormone NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 9: Non-specific - Receptor signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Vesicles "HPA065145: " "unprognostic (9.77e-2)" "unprognostic (2.02e-1)" "unprognostic (4.66e-1)" "unprognostic (7.74e-2)" INSL5 ENSG00000172410 "Insulin like 5" Q9Y5Q6 1 66797740-66801276 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 106 "intestine: 118.8" "Cell type enriched" "Detected in some" 345 "Enteroendocrine cells: 7694.3" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.2;prostate cancer: 0.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes" "Low region specificity" "Detected in some" "HPA030100, CAB033849" Enhanced "Secreted to blood" Hormone NA NA 38500000 "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 20: Enteroendocrine cells - Hormone signaling" "CAB033849: AB_2264904, HPA030100: AB_10601915" "unprognostic (2.48e-1)" "unprognostic (4.41e-2)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (2.76e-2)" "unprognostic (1.30e-1)" "unprognostic (2.62e-2)" "unprognostic (7.53e-2)" INSL6 RIF1 ENSG00000120210 "Insulin like 6" Q9Y581 9 5123880-5185647 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "retina: 6.4;testis: 14.4" "Cell type enriched" "Detected in some" 4 "Early spermatids: 165.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021364 Enhanced "Secreted to blood" Hormone NA NA "Cluster 41: Basophils - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 9: Non-specific - Receptor signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 18: Early spermatids - Unknown function" "HPA021364: AB_1851807" "unprognostic (3.85e-4)" "unprognostic (7.41e-4)" "unprognostic (1.28e-1)" "unprognostic (1.94e-1)" "unprognostic (2.22e-1)" "unprognostic (6.92e-2)" "unprognostic (2.31e-2)" "unprognostic (3.82e-2)" "unprognostic (2.30e-1)" "unprognostic (2.52e-3)" INTS3 "C1orf60, FLJ21919, INT3, SOSS-A" ENSG00000143624 "Integrator complex subunit 3" Q68E01 1 153728050-153774808 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074391 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" Other NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 37: Glandular & Luminal cells - Unknown function" 4 Nucleoli Nucleoplasm "HPA074391: AB_2686685" "unprognostic (2.36e-1)" "unprognostic (1.94e-2)" "unprognostic (8.75e-3)" "unprognostic (6.97e-3)" "unprognostic (3.26e-1)" "unprognostic (4.48e-2)" "unprognostic (1.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.75e-1)" "unprognostic (2.45e-1)" "prognostic favorable (5.42e-4)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.85e-1)" "unprognostic (1.18e-3)" "unprognostic (8.29e-2)" IPO9 "FLJ10402, Imp9" ENSG00000198700 "Importin 9" Q96P70 1 201829149-201884291 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059540 Approved Vesicles,Cytosol "Intracellular and membrane" Transport NA NA 70000 "Cluster 25: Non-specific - Unknown function" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" 3 Cytosol Vesicles "HPA059540: " "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (7.44e-3)" "unprognostic (2.02e-2)" "unprognostic (1.13e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (4.11e-5)" "unprognostic (8.92e-3)" "unprognostic (2.23e-3)" "unprognostic (2.52e-1)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.86e-4)" "unprognostic (5.05e-2)" "unprognostic (2.57e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (5.78e-4)" IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66189195-66254622 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 77.4" "Cell type enriched" "Detected in many" 6 "monocytes: 793.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.7;classical monocyte: 23.5;intermediate monocyte: 24.2;myeloid DC: 11.5;neutrophil: 12.9;non-classical monocyte: 42.3" "Group enriched" "Detected in many" 12 "dendritic cells: 11.5;granulocytes: 12.9;monocytes: 42.3" "Cancer enhanced" "Detected in many" "Leukemia: 15.6" "Breast - Adipocytes (Breast), Lung - Neutrophil_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 3 Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" ISG15 "G1P2, IFI15, UCRP" ENSG00000187608 "ISG15 ubiquitin like modifier" P05161 1 1001138-1014540 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 311.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 622.0;Hofbauer cells: 392.5;Lymphatic endothelial cells: 349.7;Proximal enterocytes: 533.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004627 Approved "Secreted to blood" Immunity NA NA 5000000 "Cluster 19: Eosinophils - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 5 "HPA004627: AB_1079152" "unprognostic (3.65e-1)" "unprognostic (1.06e-1)" "unprognostic (1.12e-2)" "unprognostic (4.62e-2)" "unprognostic (3.96e-3)" "unprognostic (1.38e-1)" "unprognostic (4.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.48e-2)" "unprognostic (3.78e-3)" "unprognostic (2.07e-3)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.11e-10)" "unprognostic (4.55e-2)" "unprognostic (4.13e-2)" "unprognostic (1.12e-2)" "unprognostic (7.46e-2)" ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 209.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 190.8;Fibroblasts: 160.2;Leydig cells: 215.7;Ovarian stromal cells: 94.3;Peritubular cells: 152.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 30.9" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 164.5" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" "No annotated function" NA NA 130000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" ISM1 "bA149I18.1, C20orf82" ENSG00000101230 "Isthmin 1" B1AKI9 20 13221274-13300651 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 43.1" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 23.6;Fibroblasts: 17.6;Microglial cells: 8.1;Smooth muscle cells: 6.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Cancer enhanced" "Detected in many" "Kidney cancer: 4.8" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 18.7" "Secreted in other tissues" "No annotated function" NA NA 17000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "unprognostic (7.13e-2)" "unprognostic (3.55e-1)" "unprognostic (4.43e-3)" "unprognostic (5.27e-3)" "unprognostic (1.84e-2)" "unprognostic (5.56e-2)" "unprognostic (2.72e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.06e-1)" "unprognostic (4.48e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.32e-6)" "unprognostic (2.58e-2)" "unprognostic (2.10e-1)" "unprognostic (6.83e-2)" "unprognostic (1.81e-2)" ISM2 "FLJ32147, TAIL1, THSD3" ENSG00000100593 "Isthmin 2" Q6H9L7 14 77474394-77498816 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "placenta: 206.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 285.0;Extravillous trophoblasts: 701.3;Syncytiotrophoblasts: 157.4" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.7" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "HPA039314, HPA039742" Supported Supported Nucleoplasm "Secreted in female reproductive system" "No annotated function" NA NA 1100000 "Cluster 58: Placenta - Pregnancy" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 Nucleoplasm "HPA039314: AB_10673239, HPA039742: AB_10673427" "unprognostic (5.69e-2)" "unprognostic (9.17e-3)" "unprognostic (2.58e-2)" "unprognostic (1.41e-3)" "unprognostic (3.73e-2)" "unprognostic (2.34e-1)" "unprognostic (2.16e-2)" "unprognostic (3.09e-3)" "unprognostic (2.11e-1)" "unprognostic (4.13e-1)" "unprognostic (8.10e-2)" "unprognostic (1.42e-2)" "unprognostic (9.36e-2)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (3.95e-1)" ITFG1 "CDA08, LNKN-1, TIP" ENSG00000129636 "Integrin alpha FG-GAP repeat containing 1" Q8TB96 16 47154387-47464149 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 242.2;Inhibitory neurons: 273.8;Oligodendrocytes: 245.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015590, HPA019728, HPA019752" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 28000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus, Vesicles, Cytosol" "HPA015590: AB_1846347, HPA019728: AB_1846348, HPA019752: " "unprognostic (6.53e-3)" "unprognostic (9.26e-3)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.27e-1)" "unprognostic (1.39e-3)" "unprognostic (3.70e-2)" "unprognostic (9.32e-2)" "unprognostic (2.47e-1)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "prognostic favorable (1.95e-8)" "unprognostic (1.56e-2)" "unprognostic (1.61e-1)" "unprognostic (3.28e-2)" "unprognostic (4.62e-3)" ITGA4 CD49D ENSG00000115232 "Integrin subunit alpha 4" P13612 2 181457202-181538940 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 46.0;lymphoid tissue: 72.1" "Cell type enhanced" "Detected in many" "B-cells: 97.4;Erythroid cells: 158.8;Kupffer cells: 101.2;Macrophages: 101.4;monocytes: 212.7;NK-cells: 269.6;Oocytes: 172.8;Plasma cells: 117.2;T-cells: 156.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 112.7;Myeloma: 80.8" "Adipose visceral - T-cells, Breast - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "cerebellum: 18.6" HPA074961 Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA 120000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 4 "Plasma membrane" "HPA074961: AB_2732273" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-1)" "prognostic favorable (8.29e-4)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (2.26e-2)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (2.57e-2)" ITGA9 "ALPHA-RLC, ITGA4L, RLC" ENSG00000144668 "Integrin subunit alpha 9" Q13797 3 37452115-37823507 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 79.3;Inhibitory neurons: 58.4;Leydig cells: 41.9;Lymphatic endothelial cells: 72.0;Microglial cells: 51.0;Oligodendrocyte precursor cells: 87.7;Peritubular cells: 70.1;Skeletal myocytes: 45.9" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 23.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 10.3;testis cancer: 15.6" "Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030609 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" Receptor NA NA 500000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Vesicles "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA030609: AB_10600815" "unprognostic (2.35e-2)" "unprognostic (3.36e-2)" "unprognostic (5.58e-2)" "unprognostic (3.94e-2)" "unprognostic (4.48e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (8.87e-3)" "unprognostic (3.23e-1)" "unprognostic (2.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-2)" "unprognostic (3.16e-2)" ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 54.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 9.7;Pancreatic endocrine cells: 10.2;Proximal tubular cells: 19.4;Salivary duct cells: 14.8;Sertoli cells: 13.6" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "basophil: 5.6;neutrophil: 3.0" "Lineage enriched" "Detected in single" 22 "granulocytes: 5.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 99.0;skin cancer: 125.1" "Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA 38000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Thyroid gland - Unknown function" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 57: Platelets - Hemostasis" 9 "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" ITGBL1 "OSCP, TIED" ENSG00000198542 "Integrin subunit beta like 1" O95965 13 101452593-101720856 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 18.9;Fibroblasts: 73.6;Oocytes: 38.2;Smooth muscle cells: 32.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 73.5" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 75.1" "Secreted - unknown location" "No annotated function" NA NA 37000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "unprognostic (1.70e-1)" "unprognostic (2.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.12e-4)" "unprognostic (1.45e-1)" "unprognostic (3.18e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (8.84e-2)" "unprognostic (2.16e-2)" "unprognostic (9.50e-2)" "unprognostic (1.13e-5)" "unprognostic (1.44e-2)" "unprognostic (2.55e-1)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.70e-4)" ITIH1 "H1P, IATIH, ITIH" ENSG00000055957 "Inter-alpha-trypsin inhibitor heavy chain 1" P19827 3 52777595-52792068 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 777 "liver: 1459.7" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 793.7" "Cancer enriched" "Detected in some" 598 "liver cancer: 329.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041639, HPA042049" Approved Approved Vesicles "Secreted to blood" "Enzyme inhibitor" NA NA 4490000 59000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" Vesicles "HPA041639: AB_10796349, HPA042049: AB_10797379" "unprognostic (1.87e-4)" "unprognostic (1.31e-3)" "unprognostic (2.38e-1)" "unprognostic (8.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-3)" "prognostic favorable (1.89e-5)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-2)" "unprognostic (4.53e-4)" "unprognostic (4.02e-3)" "unprognostic (5.70e-3)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" ITIH2 H2P ENSG00000151655 "Inter-alpha-trypsin inhibitor heavy chain 2" P19823 10 7703316-7749520 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 566 "liver: 2091.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 406.0" "Cancer enriched" "Detected in many" 279 "liver cancer: 626.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 40 "liver cancer: 147.1" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059150 Supported Approved "Golgi apparatus" "Secreted to blood" "Enzyme inhibitor" NA NA 32000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 16: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "Golgi apparatus" "HPA059150: AB_2683930" "unprognostic (4.82e-2)" "unprognostic (6.10e-2)" "unprognostic (2.48e-2)" "unprognostic (1.21e-2)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" "prognostic favorable (1.48e-4)" "unprognostic (1.37e-1)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (2.28e-1)" "unprognostic (2.02e-1)" "unprognostic (2.10e-8)" "unprognostic (9.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.35e-1)" "unprognostic (4.46e-4)" ITIH3 H3P ENSG00000162267 "Inter-alpha-trypsin inhibitor heavy chain 3" Q06033 3 52794768-52808799 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 105 "liver: 828.4" "Group enriched" "Detected in some" 5 "Hepatocytes: 920.9;Kupffer cells: 562.7" "Cancer enriched" "Detected in some" 247 "liver cancer: 273.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "liver cancer: 5.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA017373 Approved "Secreted to blood" "Enzyme inhibitor" NA NA 9100000000 "Cluster 31: Liver - Plasma proteins" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "HPA017373: AB_1851954" "unprognostic (2.07e-2)" "unprognostic (5.79e-2)" "unprognostic (1.89e-1)" "unprognostic (3.30e-4)" "unprognostic (4.28e-2)" "unprognostic (3.26e-2)" "unprognostic (5.97e-2)" "unprognostic (6.07e-2)" "unprognostic (1.49e-1)" "unprognostic (7.05e-2)" "unprognostic (1.04e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.49e-8)" "unprognostic (2.09e-4)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (9.31e-2)" ITIH4 "H4P, IHRP, ITIHL1" ENSG00000055955 "Inter-alpha-trypsin inhibitor heavy chain 4" Q14624 3 52812962-52830688 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "liver: 1807.4" "Group enriched" "Detected in many" 4 "Early spermatids: 68.4;Hepatocytes: 91.9;Late spermatids: 159.0" "Cancer enriched" "Detected in single" 27 "liver cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.4" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001835, HPA003948, CAB072872" Enhanced Approved Vesicles "Secreted to blood" "Acute phase" NA NA 3060000 58000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 62: Hepatocytes - Metabolism" Vesicles "CAB072872: AB_2665724, HPA001835: AB_1079432, HPA003948: AB_1079433" "unprognostic (6.08e-2)" "unprognostic (4.45e-2)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "unprognostic (2.64e-1)" "unprognostic (1.96e-1)" "unprognostic (5.86e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-14)" "unprognostic (1.71e-3)" "unprognostic (2.96e-2)" "unprognostic (1.52e-1)" "unprognostic (4.21e-5)" ITIH5 MGC10848 ENSG00000123243 "Inter-alpha-trypsin inhibitor heavy chain 5" 10 7559270-7666998 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 108.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 269.7;Extravillous trophoblasts: 74.0;Fibroblasts: 83.4;Microglial cells: 153.0;Smooth muscle cells: 86.7;Syncytiotrophoblasts: 211.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Rhabdoid: 78.8;skin cancer: 68.8" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038305 Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus" Vesicles "HPA038305: AB_10670662" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-3)" "unprognostic (6.80e-2)" "unprognostic (1.80e-1)" "unprognostic (5.84e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (2.90e-1)" "unprognostic (5.80e-3)" "unprognostic (6.11e-2)" "unprognostic (1.36e-1)" "unprognostic (6.79e-3)" "unprognostic (2.00e-2)" "unprognostic (4.50e-2)" "unprognostic (3.48e-2)" ITIH6 "ITIH5L, UNQ6369" ENSG00000102313 "Inter-alpha-trypsin inhibitor heavy chain family member 6" Q6UXX5 X 54748918-54798255 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.4" "Cell type enhanced" "Detected in single" "Prostatic glandular cells: 1.2" "Cancer enriched" "Detected in some" 7 "melanoma: 10.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "skin cancer: 11.3" "Breast - Breast glandular cells, Prostate - Prostate glandular cells" HPA000506 Uncertain "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 69: Skin cancer - ECM organization" "Cluster 17: Breast glandular cells - Lactation" 6 "HPA000506: AB_2666007" "unprognostic (3.40e-1)" "unprognostic (1.04e-1)" "unprognostic (9.73e-3)" "unprognostic (7.24e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-3)" "unprognostic (9.81e-2)" "unprognostic (2.66e-1)" "unprognostic (1.02e-1)" "unprognostic (6.33e-2)" "unprognostic (4.14e-4)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (2.35e-1)" ITLN1 "FLJ20022, hIntL, HL-1, ITLN, LFR" ENSG00000179914 "Intelectin 1" Q8WWA0 1 160876540-160885180 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 732.9;intestine: 1210.7" "Cell type enriched" "Detected in many" 10 "Mesothelial cells: 20526.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 61.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "intermediate monocyte: 9.2;non-classical monocyte: 24.2" "Lineage enriched" "Detected in many" 17 "monocytes: 24.2" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.8;Leukemia: 1.4;liver cancer: 1.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes" "Not detected" "Not detected" "CAB012652, HPA063275, HPA067326" Enhanced "Secreted to blood" "No annotated function" NA NA 294000000 6400000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 47: Leukemia - Hemostasis" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "CAB012652: , HPA063275: AB_2684974, HPA067326: AB_2732764" "unprognostic (9.69e-2)" "unprognostic (2.48e-2)" "unprognostic (1.31e-3)" "unprognostic (2.28e-1)" "unprognostic (1.79e-2)" "unprognostic (1.11e-1)" "unprognostic (1.59e-2)" "unprognostic (1.70e-1)" "unprognostic (5.22e-3)" "unprognostic (1.66e-2)" "unprognostic (4.38e-1)" "unprognostic (9.96e-2)" "unprognostic (3.67e-1)" "unprognostic (8.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-2)" ITLN2 HL-2 ENSG00000158764 "Intelectin 2" Q8WWU7 1 160945025-160954809 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "intestine: 396.8" "Cell type enriched" "Detected in some" 4 "Undifferentiated cells: 260.3" "Group enriched" "Detected in many" 4 "colorectal cancer: 2.8;testis cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 5.4;pancreatic cancer: 2.3;testis cancer: 3.5" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "HPA006683, HPA067326" Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA006683: AB_2129681, HPA067326: AB_2732764" "unprognostic (1.42e-1)" "unprognostic (9.62e-3)" "unprognostic (4.61e-2)" "unprognostic (7.45e-2)" "unprognostic (2.25e-1)" "unprognostic (6.84e-4)" "unprognostic (2.47e-2)" "unprognostic (5.74e-2)" "unprognostic (1.31e-2)" "unprognostic (1.36e-1)" "unprognostic (5.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.49e-1)" "unprognostic (2.31e-1)" "unprognostic (4.91e-2)" ITM2B "BRI, BRI2, BRICD2B, E25B, E3-16" ENSG00000136156 "Integral membrane protein 2B" Q9Y287 13 48232612-48270357 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Amyloidosis, Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4399.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 4399.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029292, HPA071992" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" "No annotated function" NA NA 5800000 "Cluster 21: Neutrophils - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Non-specific - Transcription" 8 "Golgi apparatus, Vesicles" "HPA029292: AB_10601917, HPA071992: AB_2686480" "unprognostic (4.66e-2)" "unprognostic (2.02e-1)" "unprognostic (1.03e-2)" "unprognostic (1.00e-1)" "unprognostic (4.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "unprognostic (9.88e-2)" "unprognostic (2.42e-1)" "unprognostic (5.89e-2)" "unprognostic (2.87e-2)" "prognostic favorable (3.73e-5)" "unprognostic (4.38e-2)" "unprognostic (4.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.22e-1)" IZUMO4 C19orf36 ENSG00000099840 "IZUMO family member 4" Q1ZYL8 19 2096429-2099593 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "testis: 430.8" "Group enriched" "Detected in many" 25 "Early spermatids: 1722.3;Late spermatids: 2634.7;Spermatocytes: 670.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "lymphoma: 10.8;Myeloma: 6.9;Rhabdoid: 2.9" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048496 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Testis - Spermatogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA048496: AB_2680419" "unprognostic (2.75e-3)" "unprognostic (1.10e-2)" "unprognostic (3.65e-2)" "prognostic favorable (7.08e-4)" "unprognostic (1.40e-1)" "unprognostic (2.18e-5)" "unprognostic (2.67e-2)" "unprognostic (1.02e-3)" "unprognostic (1.30e-1)" "unprognostic (2.48e-1)" "prognostic favorable (1.69e-4)" "unprognostic (2.12e-1)" "unprognostic (6.58e-5)" "unprognostic (6.38e-2)" "unprognostic (2.17e-1)" "unprognostic (5.68e-1)" "unprognostic (7.51e-3)" JAM3 "JAM-3, JAM-C, JAMC" ENSG00000166086 "Junctional adhesion molecule 3" Q9BX67 11 134069071-134152001 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 81.5;Extravillous trophoblasts: 77.5;Oligodendrocyte precursor cells: 71.7;Oligodendrocytes: 319.1;Rod photoreceptor cells: 68.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 5.3" "Group enriched" "Detected in many" 7 "B-cells: 5.3;T-cells: 2.4" "Low cancer specificity" "Detected in many" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003417, HPA050434" Approved Enhanced "Golgi apparatus" "Secreted to blood" "Cell adhesion" NA NA 44000 "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 51: Oligodendrocytes - Unknown function" "Golgi apparatus" "HPA003417: AB_1851981, HPA050434: AB_2681126" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (1.38e-2)" "unprognostic (3.24e-1)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.59e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (5.06e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.23e-3)" "unprognostic (2.17e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.68e-4)" JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 2922.1;intestine: 7701.3;stomach 1: 5747.7" "Cell type enriched" "Detected in many" 13 "Plasma cells: 78745.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 13.1" "Group enriched" "Detected in all" 122 "memory B-cell: 4194.2;naive B-cell: 2578.5;plasmacytoid DC: 3595.4" "Group enriched" "Detected in all" 137 "B-cells: 4194.2;dendritic cells: 3595.4" "Cancer enriched" "Detected in many" 10 "Myeloma: 12971.3" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" "No annotated function" NA NA 2200000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" JMJD8 C16orf20 ENSG00000161999 "Jumonji domain containing 8" Q96S16 16 681670-684528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" "unprognostic (2.32e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" "unprognostic (8.38e-2)" "unprognostic (1.03e-2)" "unprognostic (2.87e-1)" "unprognostic (4.79e-2)" "unprognostic (1.46e-1)" "unprognostic (1.50e-2)" "unprognostic (4.33e-2)" "unprognostic (1.63e-2)" "unprognostic (4.96e-3)" "unprognostic (5.53e-2)" "unprognostic (1.86e-1)" "unprognostic (3.29e-1)" "unprognostic (7.04e-2)" KANSL2 "C12orf41, FLJ20436, NSL2" ENSG00000139620 "KAT8 regulatory NSL complex subunit 2" Q9H9L4 12 48653211-48682238 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038497, HPA038498" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 56: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "Nucleoplasm, Plasma membrane, Cytosol" "HPA038497: AB_10674685, HPA038498: AB_2676046" "unprognostic (3.87e-3)" "unprognostic (6.18e-2)" "unprognostic (3.67e-1)" "unprognostic (8.89e-2)" "unprognostic (5.37e-2)" "unprognostic (4.73e-2)" "prognostic unfavorable (4.98e-4)" "unprognostic (5.46e-2)" "unprognostic (1.35e-3)" "unprognostic (6.16e-2)" "unprognostic (6.75e-3)" "unprognostic (4.19e-3)" "unprognostic (8.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "prognostic favorable (4.32e-4)" KARS1 "DFNB89, KARS, KARS2" ENSG00000065427 "Lysyl-tRNA synthetase 1" Q15046 16 75627474-75648643 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Intellectual disability, Neurodegeneration, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 291.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041345, HPA041550" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 82000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" 4 Cytosol "Plasma membrane" "HPA041345: AB_10795589, HPA041550: AB_10794520" "unprognostic (1.56e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-2)" "unprognostic (1.02e-2)" "unprognostic (5.39e-2)" "prognostic unfavorable (8.84e-6)" "unprognostic (6.24e-3)" "unprognostic (8.97e-3)" "unprognostic (1.18e-1)" "unprognostic (9.11e-3)" "unprognostic (8.71e-3)" "unprognostic (8.46e-2)" "unprognostic (7.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.03e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061989-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.9;Gastric mucus-secreting cells: 33.6;Intestinal goblet cells: 63.8;Proximal enterocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 28.7" "Kidney - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011800 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA 65000 "Cluster 47: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA011800: AB_1852082" "unprognostic (3.34e-1)" "unprognostic (8.86e-3)" "unprognostic (1.16e-2)" "unprognostic (4.43e-3)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (3.44e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.11e-1)" KCNIP3 "CSEN, DREAM, KCHIP3" ENSG00000115041 "Potassium voltage-gated channel interacting protein 3" Q9Y2W7 2 95297327-95386077 "Predicted intracellular proteins, Transporters" "Apoptosis, Ion transport, Potassium transport, Transcription, Transcription regulation, Transport" "Ion channel, Potassium channel, Repressor, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.5;lymphoid tissue: 24.0;parathyroid gland: 25.9" "Cell type enhanced" "Detected in many" "Astrocytes: 12.7;Excitatory neurons: 37.6;Leydig cells: 21.9;Oligodendrocyte precursor cells: 51.4;Peritubular cells: 39.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066717, HPA069797" Enhanced Approved Vesicles "Intracellular and membrane" Transport NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" 12 Vesicles "HPA066717: , HPA069797: AB_2686199" "unprognostic (1.05e-2)" "unprognostic (5.76e-2)" "unprognostic (3.33e-3)" "prognostic unfavorable (1.58e-5)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" "unprognostic (2.23e-1)" "unprognostic (2.96e-1)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (2.32e-1)" "unprognostic (4.09e-1)" "unprognostic (1.44e-3)" "unprognostic (8.90e-2)" "unprognostic (6.51e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-1)" KCP "CRIM2, FLJ33365, NET67" ENSG00000135253 "Kielin cysteine rich BMP regulator" Q6ZWJ8 7 128862042-128910719 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 16.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 54.5;Late spermatids: 32.2;Proximal enterocytes: 58.2;Skeletal myocytes: 215.7" "Cancer enhanced" "Detected in many" "renal cancer: 5.5" "Region enriched" "Detected in single" 4 "cerebellum: 3.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Gallbladder cancer: 13.0;Kidney cancer: 8.2" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "unprognostic (6.12e-2)" "unprognostic (5.49e-2)" "unprognostic (1.45e-3)" "unprognostic (6.33e-3)" "unprognostic (2.14e-1)" "unprognostic (5.24e-3)" "unprognostic (2.01e-3)" "unprognostic (3.25e-3)" "unprognostic (9.59e-2)" "unprognostic (1.52e-1)" "unprognostic (2.20e-3)" "unprognostic (6.46e-2)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (4.84e-2)" "unprognostic (7.64e-3)" KDM1A "AOF2, BHC110, KDM1, KIAA0601, LSD1" ENSG00000004487 "Lysine demethylase 1A" O60341 1 23019443-23083689 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005884, HPA053660" Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" "Developmental protein" NA NA 7700 "Cluster 29: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Spermatocytes - Spermatogenesis" 86 Nucleoplasm Cytosol "CAB005884: AB_443964, HPA053660: AB_2682220" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic favorable (6.31e-4)" "unprognostic (1.50e-1)" "unprognostic (6.83e-2)" "unprognostic (3.95e-2)" "prognostic unfavorable (4.47e-12)" "unprognostic (1.80e-2)" "unprognostic (1.99e-2)" "unprognostic (9.41e-2)" "unprognostic (3.34e-3)" "unprognostic (2.13e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (7.74e-2)" "unprognostic (1.39e-1)" KDM3B "C5orf7, JMJD1B, KIAA1082, NET22" ENSG00000120733 "Lysine demethylase 3B" Q7LBC6 5 138352685-138437028 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016610, HPA057202" Supported Enhanced Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Non-specific - Transcription" Nucleoplasm "HPA016610: AB_1852004, HPA057202: AB_2683367" "unprognostic (1.21e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-3)" "unprognostic (1.34e-1)" "unprognostic (6.72e-2)" "unprognostic (1.72e-1)" "unprognostic (5.21e-2)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (4.68e-2)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "prognostic favorable (6.67e-4)" "unprognostic (1.73e-1)" "unprognostic (3.05e-1)" "unprognostic (1.43e-1)" "unprognostic (7.60e-2)" KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873188-45112779 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 110.9;Oligodendrocyte precursor cells: 110.8;Oligodendrocytes: 246.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" Enzyme NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 66: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 4 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: AB_1858705, HPA001165: AB_1080541, HPA002111: AB_1858704" "unprognostic (1.73e-3)" "unprognostic (6.86e-3)" "unprognostic (1.45e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.65e-2)" "unprognostic (2.58e-3)" "unprognostic (8.22e-3)" "unprognostic (3.23e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.73e-1)" "unprognostic (2.24e-2)" "unprognostic (5.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-2)" KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 138.5;Endothelial cells: 159.5;Lymphatic endothelial cells: 111.0;Mesothelial cells: 193.9;Muller glia cells: 172.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 54.8" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" Receptor NA NA 11000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 15 Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" KERA "CNA2, SLRR2B" ENSG00000139330 Keratocan O60938 12 91050491-91058024 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Fibroblasts: 1.5" "Cancer enhanced" "Detected in some" "testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.8;Sarcoma: 13.0" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "amygdala: 5.5;basal ganglia: 7.3;cerebral cortex: 8.2;hippocampal formation: 7.4" HPA039321 Uncertain "Secreted to extracellular matrix" Other NA NA "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "HPA039321: AB_10795248" "unprognostic (2.77e-1)" "unprognostic (2.39e-1)" "unprognostic (3.47e-1)" "unprognostic (3.70e-1)" "unprognostic (4.76e-3)" "unprognostic (3.65e-1)" "unprognostic (6.08e-2)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-3)" "unprognostic (2.06e-2)" "unprognostic (2.53e-1)" KIAA0319 NMIG ENSG00000137261 KIAA0319 Q5VV43 6 24544104-24646191 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.4;pituitary gland: 4.0" "Group enriched" "Detected in some" 9 "Astrocytes: 113.3;Early spermatids: 52.2;Excitatory neurons: 124.8;Inhibitory neurons: 69.6;Late spermatids: 100.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enhanced" "Detected in single" "granulocytes: 1.6" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015607, HPA076313" Enhanced Supported Approved Vesicles "Secreted in brain" "Developmental protein" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA015607: AB_1852299, HPA076313: AB_2732308" "unprognostic (1.64e-1)" "unprognostic (2.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (1.72e-2)" "unprognostic (4.65e-2)" "unprognostic (9.70e-2)" "unprognostic (2.21e-5)" "unprognostic (7.88e-4)" "unprognostic (9.53e-4)" "unprognostic (1.44e-6)" "unprognostic (1.20e-1)" "unprognostic (6.97e-2)" "unprognostic (3.13e-1)" "unprognostic (3.41e-2)" KIFC2 ENSG00000167702 "Kinesin family member C2" Q96AC6 8 144466043-144474202 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 192.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 57.8;Inhibitory neurons: 38.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029264 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Other NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA029264: AB_10609999" "unprognostic (2.03e-1)" "unprognostic (1.28e-3)" "unprognostic (3.87e-3)" "unprognostic (4.12e-3)" "unprognostic (4.28e-2)" "unprognostic (1.48e-1)" "unprognostic (2.20e-2)" "unprognostic (3.41e-2)" "unprognostic (2.12e-1)" "unprognostic (9.95e-2)" "unprognostic (2.39e-2)" "unprognostic (4.48e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" "unprognostic (8.13e-2)" "unprognostic (2.71e-2)" KIR2DL4 "103AS, 15.212, CD158D" ENSG00000189013 "Killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4" Q99706 19 54803610-54814517 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "lymphoid tissue: 3.9" "Group enriched" "Detected in some" 16 "NK-cells: 35.0;T-cells: 23.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 80 "NK-cell: 8.0" "Lineage enriched" "Detected in single" 80 "NK-cells: 8.0" "Not detected" "Not detected" "Intracellular and membrane" Receptor NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 7: T-cells - T-cell receptor" 6 "unprognostic (1.98e-2)" "unprognostic (4.16e-2)" "unprognostic (1.84e-2)" "unprognostic (3.70e-4)" "unprognostic (2.23e-1)" "unprognostic (5.95e-4)" "unprognostic (1.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.92e-5)" "unprognostic (5.15e-2)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (4.53e-8)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (6.10e-4)" "unprognostic (3.59e-3)" KIR2DS4 "CD158I, cl-39, KKA3, nkat8" ENSG00000221957 "Killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4" 19 54832676-54848569 "Predicted secreted proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "NK-cells: 32.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - NK-cells (Lung)" "Secreted to blood" NA NA "Cluster 19: NK-cells - Adaptive immune response" "unprognostic (8.67e-3)" "unprognostic (3.33e-1)" "unprognostic (5.04e-3)" "unprognostic (2.18e-1)" "unprognostic (3.21e-5)" "unprognostic (2.71e-3)" "unprognostic (1.17e-1)" "unprognostic (2.40e-2)" "unprognostic (2.43e-1)" "unprognostic (2.77e-2)" "unprognostic (3.29e-2)" "unprognostic (5.00e-2)" "unprognostic (8.51e-2)" "unprognostic (4.31e-4)" "unprognostic (3.13e-3)" KIRREL2 "DKFZp564A1164, FILTRIN, MGC15718, NEPH3, NLG1" ENSG00000126259 "Kirre like nephrin family adhesion molecule 2" Q6UWL6 19 35855861-35867136 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "pancreas: 68.0" "Group enriched" "Detected in some" 6 "Bipolar cells: 52.8;Exocrine glandular cells: 13.8" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Stomach - Gastric enteroendocrine cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA071587, HPA074326" Enhanced Supported "Centriolar satellite" "Intracellular and membrane" "No annotated function" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 "Centriolar satellite" "HPA071587: AB_2732182, HPA074326: AB_2732251" "unprognostic (1.28e-2)" "unprognostic (1.80e-1)" "unprognostic (3.29e-2)" "unprognostic (3.16e-3)" "unprognostic (2.05e-3)" "unprognostic (2.29e-1)" "unprognostic (2.00e-1)" "unprognostic (1.72e-3)" "unprognostic (3.30e-2)" "unprognostic (5.56e-2)" "unprognostic (4.85e-2)" "unprognostic (2.62e-2)" "unprognostic (2.43e-6)" "unprognostic (1.72e-1)" "unprognostic (4.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.62e-2)" KIRREL3 "KIAA1867, KIRRE, NEPH2" ENSG00000149571 "Kirre like nephrin family adhesion molecule 3" Q8IZU9 11 126423358-127003460 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 26.6" "Group enriched" "Detected in some" 16 "Excitatory neurons: 265.7;Inhibitory neurons: 459.9;Oligodendrocytes: 363.2" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 8.3" "Lineage enriched" "Detected in single" 12 "dendritic cells: 8.3" "Cancer enhanced" "Detected in many" "Brain cancer: 6.9" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053324 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" 6 "HPA053324: " "unprognostic (1.92e-1)" "unprognostic (5.29e-2)" "unprognostic (1.06e-1)" "unprognostic (4.72e-2)" "unprognostic (2.50e-2)" "unprognostic (1.09e-1)" "unprognostic (4.49e-3)" "unprognostic (6.23e-3)" "unprognostic (4.08e-2)" "unprognostic (1.76e-1)" "unprognostic (7.05e-3)" "unprognostic (3.81e-2)" "unprognostic (4.06e-6)" "unprognostic (9.91e-3)" "unprognostic (1.15e-1)" "unprognostic (2.76e-2)" "unprognostic (2.92e-1)" KISS1 ENSG00000170498 "KiSS-1 metastasis suppressor" Q15726 1 204190341-204196491 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "placenta: 226.4" "Cell type enriched" "Detected in many" 28 "Syncytiotrophoblasts: 1366.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.2" "Region enriched" "Detected in many" 6 "hypothalamus: 19.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 170.5" "Lung - Alveolar cells type 2, Testis - Late spermatids" "CAB017775, HPA035542" Enhanced Approved Vesicles "Secreted in female reproductive system" "No annotated function" NA NA 860000 "Cluster 58: Placenta - Pregnancy" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 Vesicles "CAB017775: , HPA035542: AB_2674677" "unprognostic (9.64e-2)" "unprognostic (1.78e-2)" "unprognostic (1.86e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-1)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (1.63e-1)" "unprognostic (8.98e-12)" "unprognostic (2.25e-1)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "prognostic favorable (6.29e-6)" KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness, Waardenburg syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 49.9;Basal squamous epithelial cells: 57.0;Collecting duct cells: 73.9;Excitatory neurons: 45.1;Inhibitory neurons: 58.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" "Growth factor" NA NA 260000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 32: Non-specific - Cell proliferation" "Cluster 65: Neurons - Synaptic function" 1 Vesicles "HPA070395: AB_2686264" "unprognostic (7.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.22e-3)" "unprognostic (5.61e-3)" "unprognostic (7.89e-2)" "unprognostic (5.47e-3)" "unprognostic (5.03e-2)" "prognostic favorable (5.81e-7)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" KL KLA ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 124.2;parathyroid gland: 131.0" "Group enriched" "Detected in some" 4 "Prostatic glandular cells: 40.3;Proximal tubular cells: 107.5" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Region enriched" "Detected in many" 11 "choroid plexus: 102.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.0;Kidney cancer: 4.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.9;cerebral cortex: 7.1;hippocampal formation: 7.6;medulla oblongata: 4.3" "Secreted to blood" Hormone NA NA 510000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" KLHL11 FLJ10572 ENSG00000178502 "Kelch like family member 11" Q9NVR0 17 41848518-41865423 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 104.7;Late spermatids: 61.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023021, HPA052403, HPA054269" Uncertain Approved "Nucleoplasm,Nuclear membrane" "Intracellular and membrane" Other NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" 3 Nucleoplasm "Nuclear membrane" "HPA023021: AB_1852568, HPA052403: , HPA054269: AB_2682432" "unprognostic (9.90e-2)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.82e-1)" "unprognostic (2.07e-1)" "unprognostic (1.84e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-2)" "unprognostic (1.50e-1)" "unprognostic (1.83e-2)" "unprognostic (3.25e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-3)" "unprognostic (4.05e-1)" "unprognostic (2.79e-1)" "unprognostic (3.09e-2)" "unprognostic (5.07e-2)" KLK1 Klk6 ENSG00000167748 "Kallikrein 1" P06870 19 50819146-50823787 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 84 "pancreas: 9254.3;salivary gland: 5321.3" "Group enriched" "Detected in many" 4 "Exocrine glandular cells: 519.0;Intestinal goblet cells: 1401.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 50.9;renal cancer: 84.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "memory B-cell: 9.5;naive B-cell: 4.0" "Lineage enriched" "Detected in single" 13 "B-cells: 9.5" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 12.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Pancreas - Exocrine glandular cells, Prostate - Prostate glandular cells" "Region enhanced" "Detected in many" "cerebral cortex: 9.1" HPA059690 Approved "Secreted to digestive system" Enzyme NA NA 10000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 15: Pancreas - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA059690: " "unprognostic (1.51e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (1.92e-2)" "unprognostic (7.47e-3)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (8.06e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-2)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.23e-2)" KLK10 "NES1, PRSSL1" ENSG00000129451 "Kallikrein related peptidase 10" O43240 19 51012739-51020175 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Cell cycle" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 108.7;esophagus: 400.9;vagina: 184.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 75.8;Basal respiratory cells: 62.0;Club cells: 92.0;Ionocytes: 71.8;Mucus glandular cells: 62.4;Secretory cells: 79.4;Suprabasal keratinocytes: 140.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 97.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 80.0;pancreatic cancer: 79.5" "Adipose visceral - Mesothelial cells, Prostate - Prostate basal glandular cells" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA 2500000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "prognostic favorable (8.32e-4)" "unprognostic (6.06e-2)" "unprognostic (1.73e-1)" "unprognostic (4.26e-3)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.10e-2)" "unprognostic (3.94e-1)" "unprognostic (3.38e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (2.71e-2)" "unprognostic (2.46e-6)" "unprognostic (9.34e-2)" "unprognostic (7.81e-2)" "unprognostic (2.66e-3)" "unprognostic (1.52e-2)" KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 315.2;skin 1: 232.2;vagina: 180.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 211.3;Club cells: 273.7;Ionocytes: 231.6;Late spermatids: 351.6;Mesothelial cells: 304.1;Squamous epithelial cells: 214.1;Suprabasal keratinocytes: 644.6" "Cancer enhanced" "Detected in many" "prostate cancer: 53.3" "Region enriched" "Detected in some" 26 "choroid plexus: 96.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 61.5;thyroid cancer: 43.0" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Skin - Keratinocyte (other), Testis - Late spermatids, Thyroid - Parafollicular cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "basal ganglia: 1.0" CAB026340 Approved "Secreted in other tissues" Enzyme NA NA 1800000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Suprabasal keratinocytes - Cornification" "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "cervix: 105.5;esophagus: 202.8;salivary gland: 62.8;vagina: 96.4" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 226.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.7" "Region enriched" "Detected in single" 18 "choroid plexus: 4.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 6.1" "Lung - Respiratory ciliated cells, Testis - Late spermatids, Thyroid - Parafollicular cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB025473 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Suprabasal keratinocytes - Cornification" "CAB025473: " "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-3)" "unprognostic (1.15e-1)" "unprognostic (5.80e-3)" "unprognostic (4.99e-3)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "prognostic favorable (8.01e-4)" "unprognostic (8.50e-3)" KLK13 KLK-L4 ENSG00000167759 "Kallikrein related peptidase 13" Q9UKR3 19 51055626-51065114 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 505.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 61.9;Late spermatids: 245.6;Serous glandular cells: 55.6;Squamous epithelial cells: 99.5;Suprabasal keratinocytes: 213.8" "Group enriched" "Detected in many" 4 "cervical cancer: 20.6;head and neck cancer: 42.3;melanoma: 10.9" "Region enhanced" "Detected in single" "choroid plexus: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 11.1;Esophageal cancer: 5.4;ovarian cancer: 6.6" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA062136 Enhanced "Secreted in other tissues" Enzyme NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA062136: AB_2684694" "unprognostic (1.99e-3)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (3.66e-2)" "unprognostic (3.43e-1)" "unprognostic (2.99e-2)" "unprognostic (1.69e-1)" "unprognostic (6.76e-2)" "unprognostic (2.18e-2)" "unprognostic (8.30e-2)" "unprognostic (7.07e-6)" "unprognostic (7.33e-2)" "unprognostic (2.53e-1)" "unprognostic (6.38e-2)" "unprognostic (7.06e-2)" KLK14 KLK-L6 ENSG00000129437 "Kallikrein related peptidase 14" Q9P0G3 19 51077495-51084245 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 9.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 7.8;head and neck cancer: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" CAB026228 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 13: Skin - Cornification" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" "CAB026228: " "unprognostic (2.08e-1)" "unprognostic (1.22e-1)" "unprognostic (2.44e-2)" "unprognostic (2.60e-2)" "unprognostic (1.23e-1)" "unprognostic (6.12e-2)" "unprognostic (4.91e-2)" "unprognostic (5.79e-2)" "unprognostic (7.84e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (8.87e-2)" "unprognostic (2.04e-8)" "unprognostic (1.93e-1)" "unprognostic (3.74e-3)" "unprognostic (1.94e-2)" "unprognostic (8.08e-2)" KLK15 "ACO, HSRNASPH, prostinogen" ENSG00000174562 "Kallikrein related peptidase 15" Q9H2R5 19 50825289-50837213 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.2;salivary gland: 3.9;testis: 1.1" "Cell type enhanced" "Detected in some" "Early spermatids: 5.2;Intestinal goblet cells: 33.8;Late spermatids: 9.5;Spermatocytes: 14.5;Spermatogonia: 8.7" "Group enriched" "Detected in some" 4 "prostate cancer: 3.5;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 2.4" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA019802 Uncertain "Secreted to blood" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "HPA019802: AB_1852601" "unprognostic (6.06e-2)" "unprognostic (2.85e-1)" "unprognostic (8.13e-2)" "unprognostic (2.90e-1)" "unprognostic (2.29e-2)" "unprognostic (1.16e-1)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-1)" "unprognostic (2.72e-2)" KLK2 ENSG00000167751 "Kallikrein related peptidase 2" P20151 19 50861568-50880567 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 85 "prostate: 546.6" "Cell type enriched" "Detected in some" 358 "Prostatic glandular cells: 6422.7" "Cancer enriched" "Detected in some" 1666 "prostate cancer: 989.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 134 "prostate cancer: 207.3" "Prostate - Prostate glandular cells" HPA000764 Supported "Secreted in male reproductive system" Enzyme NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Neuronal - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" "HPA000764: AB_1079700" "unprognostic (3.05e-2)" "unprognostic (2.40e-1)" "unprognostic (1.69e-1)" "unprognostic (8.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (3.22e-1)" "unprognostic (6.44e-2)" "unprognostic (8.06e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-3)" "unprognostic (7.56e-2)" "unprognostic (8.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.04e-1)" KLK3 "APS, PSA" ENSG00000142515 "Kallikrein related peptidase 3" P07288 19 50854915-50860764 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 320 "prostate: 7740.7" "Cell type enriched" "Detected in some" 900 "Prostatic glandular cells: 23789.4" "Cancer enriched" "Detected in some" 3905 "prostate cancer: 4241.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 1800 "prostate cancer: 2405.5" "Prostate - Prostate glandular cells, Testis - Late spermatids" "CAB000070, HPA000764" Enhanced "Secreted in male reproductive system" Enzyme NA NA 7000000 "Cluster 64: Neuronal - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "CAB000070: , HPA000764: AB_1079700" "unprognostic (5.06e-3)" "unprognostic (5.60e-2)" "unprognostic (9.93e-2)" "unprognostic (3.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.13e-3)" "unprognostic (1.94e-1)" "unprognostic (4.64e-1)" "unprognostic (3.15e-1)" KLK4 "EMSP, EMSP1, KLK-L1, PRSS17, PSTS" ENSG00000167749 "Kallikrein related peptidase 4" Q9Y5K2 19 50906351-50911395 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Hydrolase, Protease, Serine protease" "Amelogenesis imperfecta, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "prostate: 277.9" "Cell type enriched" "Detected in some" 91 "Prostatic glandular cells: 606.0" "Cancer enriched" "Detected in many" 55 "prostate cancer: 463.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 16 "prostate cancer: 107.3" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 5.9" HPA051839 Enhanced "Secreted in male reproductive system" Enzyme NA NA "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 2 "HPA051839: AB_2681632" "unprognostic (3.58e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-3)" "unprognostic (1.66e-3)" "unprognostic (3.11e-2)" "unprognostic (4.35e-1)" "unprognostic (3.18e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-2)" "unprognostic (8.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (4.20e-3)" "unprognostic (3.27e-3)" "unprognostic (2.21e-2)" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" KLK5 "KLK-L2, SCTE" ENSG00000167754 "Kallikrein related peptidase 5" Q9Y337 19 50943303-50953093 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 196.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 32.6;Breast myoepithelial cells: 30.1;Early spermatids: 67.4;Late spermatids: 203.1;Mucus glandular cells: 114.9" "Group enriched" "Detected in many" 5 "head and neck cancer: 73.1;melanoma: 32.1;ovarian cancer: 112.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 132.4;head and neck cancer: 188.7" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014343, CAB025503, CAB026341, HPA073512" Enhanced "Secreted in other tissues" Enzyme NA NA 2500000 "Cluster 13: Skin - Cornification" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" 2 "CAB025503: , CAB026341: , HPA014343: AB_1852603, HPA073512: " "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.30e-4)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.04e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" "unprognostic (2.21e-1)" "unprognostic (2.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.16e-3)" "prognostic unfavorable (3.85e-6)" KLK6 "Bssp, Klk7, neurosin, PRSS18, PRSS9" ENSG00000167755 "Kallikrein related peptidase 6" Q92876 19 50958631-50969673 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 457.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 25.1;Mucus glandular cells: 65.5;Oligodendrocytes: 81.8;Salivary duct cells: 23.5;Secretory cells: 97.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 131.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 650.6;Gallbladder cancer: 349.4" "Adipose visceral - Mesothelial cells, Kidney - Podocytes" "Region enhanced" "Detected in all" "pons and medulla: 167.9" "Region enhanced" "Detected in all" "spinal cord: 448.7" HPA051837 Supported "Nucleoplasm,Nuclear membrane,Cytokinetic bridge" "Secreted in other tissues" Enzyme Yes No 10000000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 100 Nucleoplasm "Nuclear membrane, Cytokinetic bridge" "HPA051837: " "unprognostic (7.30e-2)" "unprognostic (3.32e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.10e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.85e-4)" "unprognostic (3.02e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (9.07e-2)" "prognostic unfavorable (1.27e-4)" KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 92.0;skin 1: 194.8" "Group enriched" "Detected in some" 4 "Mucus glandular cells: 192.7;Salivary duct cells: 89.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bile duct cancer: 63.9;colorectal cancer: 23.3;Gastric cancer: 17.6;head and neck cancer: 31.1;ovarian cancer: 27.9" "Adipose visceral - Mesothelial cells, Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" Enzyme NA NA 3700000 "Cluster 13: Skin - Cornification" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 114.7;skin 1: 99.5;vagina: 45.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 84.9;Mesothelial cells: 37.5;Secretory cells: 26.1;Squamous epithelial cells: 25.1;Suprabasal keratinocytes: 149.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 80.1" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enriched" "Detected in single" 4 "basal ganglia: 1.9" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" Enzyme NA NA 3200000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 13 Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" KLK9 KLK-L3 ENSG00000213022 "Kallikrein related peptidase 9" Q9UKQ9 19 51002508-51009634 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 11.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.1;head and neck cancer: 8.6" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" CAB025049 Enhanced "Secreted in other tissues" Enzyme NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "CAB025049: " "unprognostic (3.22e-2)" KLKB1 KLK3 ENSG00000164344 "Kallikrein B1" P03952 4 186226438-186258471 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Inflammatory response" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 28 "liver: 318.1" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 223.6" "Cancer enriched" "Detected in some" 17 "liver cancer: 27.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" "Blood coagulation" NA NA 28900000000 5300000000 "Cluster 31: Liver - Plasma proteins" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 62: Hepatocytes - Metabolism" 8 "unprognostic (4.80e-2)" "unprognostic (4.53e-3)" "unprognostic (4.36e-2)" "unprognostic (4.17e-2)" "unprognostic (5.93e-2)" "unprognostic (1.90e-2)" "unprognostic (1.15e-2)" "unprognostic (2.83e-1)" "unprognostic (8.14e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-2)" "unprognostic (6.01e-2)" "unprognostic (7.30e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" KNG1 "BDK, BK, HK, HMWK, KNG" ENSG00000113889 "Kininogen 1" P01042 3 186717348-186744410 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis, Inflammatory response" "Protease inhibitor, Thiol protease inhibitor, Vasoactive, Vasodilator" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "liver: 3097.3" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 1654.3" "Cancer enriched" "Detected in some" 126 "liver cancer: 608.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Gastric cancer: 4.6;liver cancer: 8.0" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001616, HPA001645, CAB009809" Enhanced "Secreted to blood" "Blood coagulation" NA NA 90000000000 47000000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "CAB009809: AB_2134781, HPA001616: AB_1079216, HPA001645: AB_1079215" "unprognostic (3.88e-1)" "unprognostic (1.63e-1)" "unprognostic (2.82e-1)" "unprognostic (3.27e-1)" "unprognostic (8.30e-3)" "unprognostic (2.04e-1)" "prognostic favorable (1.28e-6)" "unprognostic (1.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (9.96e-2)" "unprognostic (1.65e-1)" "unprognostic (3.45e-3)" "unprognostic (5.20e-2)" "unprognostic (2.46e-1)" "unprognostic (4.52e-2)" KREMEN2 "KRM2, MGC10791" ENSG00000131650 "Kringle containing transmembrane protein 2" Q8NCW0 16 2964216-2968383 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 3.9;skin 1: 7.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.7;Basal squamous epithelial cells: 10.6;Cone photoreceptor cells: 10.2;Intestinal goblet cells: 15.9;Rod photoreceptor cells: 12.1;Spermatocytes: 14.8;Spermatogonia: 11.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.2;naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 38.8" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA003223 Uncertain Approved Nucleoli "Intracellular and membrane" Other NA NA "Cluster 13: Skin - Cornification" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoli "HPA003223: AB_1079217" "unprognostic (8.36e-2)" "unprognostic (4.65e-1)" "unprognostic (6.24e-3)" "unprognostic (4.61e-2)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (4.02e-3)" "prognostic unfavorable (8.98e-4)" "unprognostic (3.34e-2)" "unprognostic (1.57e-2)" "unprognostic (8.03e-2)" "unprognostic (8.57e-2)" "unprognostic (7.79e-12)" "unprognostic (6.69e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-2)" "unprognostic (6.58e-3)" KRT10 "CK10, K10, KPP" ENSG00000186395 "Keratin 10" P13645 17 40818117-40822614 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 14 "skin 1: 15346.8" "Cell type enriched" "Detected in all" 8 "Suprabasal keratinocytes: 6950.7" "Group enriched" "Detected in all" 4 "head and neck cancer: 310.0;melanoma: 562.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 214.5" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000132, HPA012014" Enhanced "Secreted in other tissues" "No annotated function" NA NA 18000000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 55: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "CAB000132: , HPA012014: AB_1852195" "unprognostic (3.07e-1)" "unprognostic (5.19e-2)" "unprognostic (1.71e-1)" "unprognostic (1.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.60e-1)" "unprognostic (3.02e-2)" "unprognostic (1.29e-2)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (1.00e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (9.32e-5)" "unprognostic (1.64e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-2)" "unprognostic (8.10e-2)" KRTDAP "KDAP, UNQ467" ENSG00000188508 "Keratinocyte differentiation associated protein" P60985 19 35487324-35495558 "Plasma proteins, Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skin 1: 5957.2;vagina: 1682.9" "Cell type enriched" "Detected in some" 15 "Suprabasal keratinocytes: 8460.7" "Group enriched" "Detected in many" 7 "head and neck cancer: 486.4;melanoma: 207.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "Esophageal cancer: 42.8;head and neck cancer: 38.2" "Region enriched" "Detected in single" 6 "white matter: 1.6" "Not detected" "Not detected" HPA063474 Enhanced "Secreted in other tissues" Other NA NA 34000000 "Cluster 13: Skin - Cornification" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA063474: AB_2685019" "unprognostic (4.55e-2)" "unprognostic (2.46e-1)" "unprognostic (1.64e-1)" "unprognostic (6.11e-2)" "unprognostic (1.59e-1)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (3.80e-2)" "unprognostic (1.50e-1)" "unprognostic (2.76e-1)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-2)" LACRT LACRITIN ENSG00000135413 Lacritin Q9GZZ8 12 54630811-54634895 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "salivary gland: 12.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 304 "breast cancer: 15.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells" "Secreted to digestive system" "No annotated function" NA NA 230000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 27: Breast cancer - Unknown function" LACTB "FLJ14902, MRPL56" ENSG00000103642 "Lactamase beta" P83111 15 63121833-63142061 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protease" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 126.6;monocytes: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036361, HPA036362" Supported Supported Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Non-specific - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Macrophages - Innate immune response" Mitochondria "HPA036361: AB_10672244, HPA036362: AB_10670798" "unprognostic (6.07e-2)" "unprognostic (2.02e-1)" "unprognostic (2.22e-2)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (3.10e-2)" "unprognostic (8.08e-2)" "unprognostic (6.25e-2)" "unprognostic (8.98e-2)" "unprognostic (3.08e-1)" "unprognostic (6.22e-3)" "unprognostic (5.16e-3)" "unprognostic (6.28e-2)" "unprognostic (3.24e-1)" "unprognostic (8.64e-2)" "unprognostic (7.90e-2)" "unprognostic (3.88e-3)" LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 352.0;skin 1: 208.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 151.4;Distal enterocytes: 143.5;Ductal cells: 156.4;Oocytes: 146.3;Proximal enterocytes: 232.2;Squamous epithelial cells: 213.2;Suprabasal keratinocytes: 354.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 257.9" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Actin filaments" "HPA007256: AB_1852681, HPA028732: AB_10602916" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.82e-1)" "unprognostic (7.55e-3)" "unprognostic (4.66e-2)" "unprognostic (7.41e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (9.11e-2)" "unprognostic (2.31e-2)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" LAG3 CD223 ENSG00000089692 "Lymphocyte activating 3" P18627 12 6772512-6778455 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.3;lymphoid tissue: 23.0;ovary: 18.0" "Cell type enhanced" "Detected in many" "Leydig cells: 38.5;Ovarian stromal cells: 28.1;Peritubular cells: 64.9;T-cells: 53.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 8 "choroid plexus: 8.5" "Immune cell enhanced" "Detected in many" "gdT-cell: 12.6;MAIT T-cell: 10.0;memory CD8 T-cell: 11.0" "Lineage enriched" "Detected in single" 49 "T-cells: 12.6" "Cancer enhanced" "Detected in some" "lymphoma: 8.0" "Breast - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002301, HPA013967" Enhanced "Intracellular and membrane" Immunity NA NA 13000 "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "CAB002301: AB_564101, HPA013967: AB_1846277" "unprognostic (9.39e-2)" "prognostic favorable (3.89e-4)" "unprognostic (8.88e-2)" "unprognostic (7.00e-3)" "unprognostic (1.08e-1)" "unprognostic (6.74e-3)" "unprognostic (8.85e-2)" "unprognostic (4.63e-3)" "unprognostic (1.94e-2)" "unprognostic (1.97e-3)" "unprognostic (8.71e-2)" "unprognostic (9.93e-2)" "prognostic unfavorable (4.62e-11)" "unprognostic (3.07e-2)" "unprognostic (2.70e-1)" "unprognostic (6.13e-2)" "unprognostic (8.19e-3)" LAIR2 "CD306, LAIR-2" ENSG00000167618 "Leukocyte associated immunoglobulin like receptor 2" Q6ISS4 19 54497879-54510687 "CD markers, Predicted intracellular proteins, Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.6;pituitary gland: 2.5" "Cell type enriched" "Detected in some" 7 "Extravillous trophoblasts: 882.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 9 "gdT-cell: 14.0;memory CD4 T-cell: 13.8;memory CD8 T-cell: 19.6;naive CD8 T-cell: 13.3;T-reg: 49.6" "Lineage enriched" "Detected in many" 40 "T-cells: 49.6" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.4" "Thyroid - T-cells" "Secreted to blood" Receptor NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 4: Extravillous trophoblasts - Unknown function" 5 "unprognostic (1.99e-3)" "unprognostic (7.49e-2)" "unprognostic (4.19e-2)" "unprognostic (1.02e-2)" "unprognostic (1.42e-1)" "unprognostic (4.86e-4)" "unprognostic (1.06e-2)" "unprognostic (8.37e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-1)" "unprognostic (2.21e-1)" "unprognostic (9.52e-2)" "unprognostic (3.68e-9)" "unprognostic (1.21e-2)" "unprognostic (3.15e-3)" "unprognostic (3.40e-5)" "unprognostic (6.71e-2)" LALBA "HAMLET, LYZG, LYZL7" ENSG00000167531 "Lactalbumin alpha" P00709 12 48567684-48570066 "Cancer-related genes, Metabolic proteins, Predicted secreted proteins" "Lactose biosynthesis" "Milk protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 922 "breast: 2109.2" "Cell type enriched" "Detected in some" 143 "Breast glandular cells: 50128.3" "Cancer enriched" "Detected in single" 599 "breast cancer: 29.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 45 "breast cancer: 2.1;Rhabdoid: 6.8" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026343, HPA029855, HPA029856" Enhanced "Secreted in female reproductive system" Other NA NA 91000 "Cluster 73: Breast - Lactation" "Cluster 3: Rhabdoid - Membrane components" "Cluster 17: Breast glandular cells - Lactation" "CAB026343: , HPA029855: AB_2673222, HPA029856: AB_10671362" "unprognostic (7.85e-2)" LAMA1 LAMA ENSG00000101680 "Laminin subunit alpha 1" P25391 18 6941742-7117797 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.2;testis: 5.7" "Cell type enhanced" "Detected in many" "Astrocytes: 86.1;Distal enterocytes: 151.5;Granulosa cells: 27.5;Intestinal goblet cells: 43.2;Paneth cells: 38.4;Proximal enterocytes: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 34.9" "Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010179 Enhanced "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 19: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" "CAB010179: AB_2133741" "unprognostic (2.75e-1)" "unprognostic (3.66e-4)" "unprognostic (2.08e-1)" "unprognostic (3.56e-1)" "unprognostic (4.97e-3)" "unprognostic (3.66e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (2.23e-2)" "unprognostic (3.43e-2)" "unprognostic (3.02e-1)" "unprognostic (6.80e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-2)" "unprognostic (4.85e-1)" "unprognostic (3.47e-2)" "unprognostic (7.34e-3)" LAMA2 LAMM ENSG00000196569 "Laminin subunit alpha 2" P24043 6 128883138-129516566 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 142.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 352.0;Fibroblasts: 218.4;Leydig cells: 181.2;Microglial cells: 661.1;Oligodendrocytes: 149.9;Peritubular cells: 211.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 5 "T-cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040310, CAB078182" Enhanced "Secreted to extracellular matrix" "Cell adhesion" NA NA 55000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "CAB040310: , CAB078182: AB_2665829" "unprognostic (1.17e-1)" "unprognostic (5.87e-2)" "unprognostic (2.17e-2)" "unprognostic (3.17e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.65e-2)" "unprognostic (9.73e-2)" "unprognostic (3.67e-2)" "unprognostic (2.44e-3)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (4.04e-2)" "unprognostic (1.24e-3)" "unprognostic (6.16e-2)" "unprognostic (5.41e-3)" "prognostic unfavorable (3.65e-5)" LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 128.1;Basal respiratory cells: 105.5;Distal enterocytes: 104.5;Gastric mucus-secreting cells: 122.0;Paneth cells: 84.4;Salivary duct cells: 74.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 161.4" "Kidney - Endothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "Cell adhesion" NA NA 1800000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Extravillous trophoblasts: 140.7;Fibroblasts: 121.0;Leydig cells: 168.8;Lymphatic endothelial cells: 212.7;Mesothelial cells: 178.8;Microglial cells: 119.0;Oligodendrocyte precursor cells: 150.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 113.3" "Breast - Endothelial cells, Colon - Smooth muscle cells, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Cell adhesion" NA NA 320000 "Cluster 62: Connective tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" LAMA5 ENSG00000130702 "Laminin subunit alpha 5" O15230 20 62307955-62367312 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 101.8;Glandular and luminal cells: 70.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA058389, CAB078157" Enhanced Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 1800000 "Cluster 66: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" Vesicles "CAB078157: AB_2665809, HPA058389: " "unprognostic (8.01e-2)" "unprognostic (2.47e-1)" "unprognostic (1.92e-2)" "unprognostic (3.42e-3)" "unprognostic (1.17e-1)" "unprognostic (9.90e-3)" "unprognostic (4.01e-3)" "unprognostic (5.45e-2)" "unprognostic (8.99e-2)" "unprognostic (1.34e-2)" "unprognostic (5.98e-3)" "unprognostic (2.98e-3)" "unprognostic (4.04e-2)" "unprognostic (9.86e-3)" "unprognostic (2.07e-1)" "unprognostic (9.76e-2)" "unprognostic (1.33e-2)" LAMB1 CLM ENSG00000091136 "Laminin subunit beta 1" P07942 7 107923799-108003213 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 218.7;Fibroblasts: 156.5;Mesothelial cells: 175.0;Peritubular cells: 159.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 54.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004056, HPA004132, CAB004256" Enhanced "Secreted to extracellular matrix" "Cell adhesion" NA NA 250000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 3 "CAB004256: AB_627867, HPA004056: AB_1079226, HPA004132: AB_1079225" "unprognostic (2.39e-1)" "unprognostic (6.45e-3)" "unprognostic (2.01e-1)" "unprognostic (6.75e-2)" "unprognostic (3.45e-3)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (3.77e-2)" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "unprognostic (3.44e-1)" "unprognostic (5.01e-2)" "unprognostic (2.87e-2)" "unprognostic (4.50e-3)" "unprognostic (1.75e-1)" "unprognostic (4.45e-2)" "unprognostic (1.46e-1)" LAMB2 "LAMS, NPHS5" ENSG00000172037 "Laminin subunit beta 2" P55268 3 49121114-49133118 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 154.1;Leydig cells: 141.1;Lymphatic endothelial cells: 133.0;Peritubular cells: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000053, HPA001895, HPA050033, CAB078160" Supported Approved Vesicles,Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA 25000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 Vesicles Cytosol "CAB000053: AB_2313665, CAB078160: AB_2665799, HPA001895: AB_1079227, HPA050033: " "unprognostic (1.12e-2)" "unprognostic (4.40e-2)" "unprognostic (5.14e-3)" "unprognostic (1.10e-1)" "unprognostic (4.08e-1)" "unprognostic (4.01e-1)" "unprognostic (5.59e-2)" "unprognostic (6.80e-2)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (1.26e-1)" "unprognostic (4.96e-2)" "unprognostic (1.21e-3)" "unprognostic (1.78e-1)" "unprognostic (4.38e-2)" "unprognostic (6.20e-2)" "unprognostic (1.24e-2)" LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 71.3;urinary bladder: 70.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 215.0;Basal respiratory cells: 405.4;Ductal cells: 165.9;Gastric mucus-secreting cells: 175.7;Ionocytes: 178.6;Salivary duct cells: 225.6" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 41.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 438.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 20000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" LAMB4 ENSG00000091128 "Laminin subunit beta 4" A4D0S4 7 108023548-108130361 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 37.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 31.4;Basal squamous epithelial cells: 25.5;Early spermatids: 14.1;Late spermatids: 11.1;Suprabasal keratinocytes: 11.7" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Bladder cancer: 2.8;cervical cancer: 1.3;Uterine cancer: 2.8" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA020242, HPA024247" Approved "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 13: Skin - Cornification" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA020242: AB_2670388, HPA024247: AB_2671496" "unprognostic (7.41e-2)" "unprognostic (1.79e-1)" "unprognostic (4.85e-2)" "unprognostic (1.77e-1)" "unprognostic (3.79e-2)" "unprognostic (6.29e-4)" "unprognostic (8.90e-3)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.27e-2)" "unprognostic (1.23e-4)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" LAMC1 LAMB2 ENSG00000135862 "Laminin subunit gamma 1" P11047 1 183023420-183145592 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 224.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 206.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "testis cancer: 422.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001908, HPA001909, CAB004486, CAB078163" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 100000000 "Cluster 14: Non-specific - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Endoplasmic reticulum, Plasma membrane" "CAB004486: AB_627870, CAB078163: AB_2665817, HPA001908: AB_1079229, HPA001909: AB_1079230" "unprognostic (1.46e-1)" "unprognostic (1.05e-2)" "unprognostic (8.30e-2)" "unprognostic (8.84e-3)" "unprognostic (3.75e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.38e-2)" "unprognostic (2.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-3)" "unprognostic (1.10e-3)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.85e-5)" LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 37.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 120.9;Basal respiratory cells: 202.4;Basal squamous epithelial cells: 151.8;Ductal cells: 154.8;Pancreatic endocrine cells: 161.3;Secretory cells: 97.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 231.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 511.2" "Breast - Breast myoepithelial cells, Liver - Cholangiocyte, Pancreas - Ductal cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004257, HPA024638, HPA046539, HPA046540, CAB078165" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" No No 130000 "Cluster 45: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Endoplasmic reticulum, Golgi apparatus" "CAB004257: AB_627873, CAB078165: AB_2665800, HPA024638: AB_1852689, HPA046539: , HPA046540: " "unprognostic (7.27e-3)" "unprognostic (7.21e-3)" "unprognostic (3.24e-1)" "unprognostic (6.20e-3)" "unprognostic (9.43e-2)" "unprognostic (4.94e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (7.11e-5)" "unprognostic (2.77e-1)" "unprognostic (7.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" LAMC3 DKFZp434E202 ENSG00000050555 "Laminin subunit gamma 3" Q9Y6N6 9 131009174-131094473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 47.1" "Group enriched" "Detected in many" 5 "Leydig cells: 111.0;Peritubular cells: 359.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 7.8;Rhabdoid: 9.2" "Kidney - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022814 Enhanced "Secreted to extracellular matrix" "Cell adhesion" NA NA 1100000 "Cluster 57: Lung - Lung function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 3: Rhabdoid - Membrane components" "Cluster 9: Endometrial stromal cells - Transcription" "HPA022814: AB_2670960" "unprognostic (9.77e-2)" "unprognostic (1.90e-1)" "unprognostic (9.55e-3)" "unprognostic (2.09e-1)" "unprognostic (2.15e-1)" "unprognostic (1.22e-2)" "unprognostic (1.38e-2)" "unprognostic (2.28e-3)" "unprognostic (6.27e-2)" "unprognostic (1.83e-1)" "unprognostic (1.58e-1)" "unprognostic (3.38e-1)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (1.63e-1)" "unprognostic (3.34e-1)" "unprognostic (7.83e-2)" LARGE2 "FLJ35207, GYLTL1B, PP5656" ENSG00000165905 "LARGE xylosyl- and glucuronyltransferase 2" Q8N3Y3 11 45921621-45929096 "Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 35.3" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 42.8;Cytotrophoblasts: 180.0;Syncytiotrophoblasts: 98.5" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 13 "choroid plexus: 26.5" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.4;naive B-cell: 2.1" "Lineage enriched" "Detected in single" 4 "B-cells: 2.1" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056621 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 34: B-cells - Unknown function" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "HPA056621: AB_2683194" "unprognostic (9.82e-2)" "unprognostic (3.63e-2)" "unprognostic (3.65e-2)" "unprognostic (2.43e-2)" "unprognostic (6.20e-2)" "unprognostic (4.46e-3)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (2.87e-1)" "unprognostic (3.30e-2)" "unprognostic (6.94e-2)" "prognostic favorable (3.04e-12)" "unprognostic (2.31e-1)" "unprognostic (9.77e-2)" "unprognostic (1.66e-1)" "unprognostic (1.18e-2)" LAT LAT1 ENSG00000213658 "Linker for activation of T cells" O43561 16 28984826-28990784 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "granulocytes: 20.7;NK-cells: 20.1;T-cells: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "basophil: 308.6;gdT-cell: 303.5;MAIT T-cell: 212.3;memory CD4 T-cell: 295.3;memory CD8 T-cell: 306.9;naive CD4 T-cell: 276.3;naive CD8 T-cell: 267.4;NK-cell: 114.7;T-reg: 411.7" "Group enriched" "Detected in all" 172 "granulocytes: 308.6;NK-cells: 114.7;T-cells: 411.7" "Cancer enhanced" "Detected in all" "Leukemia: 87.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002223, HPA011157, CAB012978, CAB079960" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" Immunity NA NA 140000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 6 "Plasma membrane" "Golgi apparatus" "CAB002223: AB_563852, CAB012978: , CAB079960: , HPA011157: AB_1079237" "unprognostic (4.35e-3)" "unprognostic (5.17e-3)" "unprognostic (1.25e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-1)" "unprognostic (7.15e-5)" "unprognostic (1.17e-1)" "unprognostic (5.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (1.52e-3)" "unprognostic (5.33e-2)" "unprognostic (1.02e-8)" "unprognostic (1.04e-2)" "unprognostic (5.58e-2)" "unprognostic (3.25e-1)" "unprognostic (1.51e-4)" LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.4;lymphoid tissue: 55.0" "Group enriched" "Detected in many" 4 "B-cells: 89.0;granulocytes: 128.2;Hofbauer cells: 106.6;Kupffer cells: 69.5;Langerhans cells: 104.6;Macrophages: 85.4;NK-cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 873.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Leukemia: 200.3;lymphoma: 102.9" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 73: B-cells - B-cell function" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" LBP BPIFD2 ENSG00000129988 "Lipopolysaccharide binding protein" P18428 20 38346482-38377013 "Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity, Lipid transport, Transport" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 1304.6" "Cell type enriched" "Detected in some" 14 "Hepatocytes: 388.2" "Cancer enriched" "Detected in many" 20 "liver cancer: 356.7" "Region enhanced" "Detected in single" "medulla oblongata: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Brain cancer: 6.7;breast cancer: 2.7;liver cancer: 2.3;lymphoma: 1.8;thyroid cancer: 2.9" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001508, CAB025905" Approved "Secreted to blood" Transport NA NA 25000000000 1300000000 "Cluster 31: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Hepatocytes - Metabolism" 1 "CAB025905: , HPA001508: AB_1079241" "unprognostic (4.20e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (4.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-2)" "unprognostic (5.50e-2)" "unprognostic (2.48e-3)" "unprognostic (6.15e-2)" "unprognostic (2.12e-1)" "unprognostic (7.93e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (3.62e-12)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-1)" LCAT ENSG00000213398 "Lecithin-cholesterol acyltransferase" P04180 16 67939750-67944131 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Hydrolase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 276.1" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044767 Approved Nucleoplasm "Secreted to blood" Enzyme NA NA 6470000000 6400000000 "Cluster 22: Eosinophils - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 2 Nucleoplasm "HPA044767: AB_2756312" "unprognostic (3.34e-2)" "unprognostic (3.56e-2)" "prognostic unfavorable (8.50e-4)" "unprognostic (5.43e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-1)" "prognostic favorable (4.21e-8)" "unprognostic (6.42e-2)" "unprognostic (4.26e-1)" "unprognostic (4.12e-1)" "unprognostic (1.50e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (9.93e-2)" "unprognostic (1.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.90e-3)" LCN1 "MGC71975, PMFA, TLC, TP, VEGP" ENSG00000160349 "Lipocalin 1" P31025 9 135521438-135526540 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Sensory transduction, Taste, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 12.5;seminal vesicle: 7.7" "Group enriched" "Detected in some" 6 "Paneth cells: 1.2;Secretory cells: 4.4" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.1" "Region enhanced" "Detected in single" "hippocampal formation: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.6" "Not detected" "Not detected" "Secreted in other tissues" Transport NA NA 3800000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "unprognostic (5.50e-3)" "unprognostic (1.10e-1)" "unprognostic (7.12e-2)" "unprognostic (3.99e-1)" "unprognostic (1.08e-2)" "unprognostic (1.11e-4)" "unprognostic (1.22e-1)" "unprognostic (7.84e-2)" "unprognostic (9.47e-2)" "unprognostic (3.94e-8)" "unprognostic (2.07e-3)" "unprognostic (3.03e-2)" "unprognostic (5.83e-2)" LCN10 ENSG00000187922 "Lipocalin 10" Q6JVE6 9 136738167-136743356 "Predicted secreted proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 31.5" "Cell type enriched" "Detected in single" 8 "B-cells: 6.4" "Cancer enriched" "Detected in single" 8 "thyroid cancer: 1.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "memory B-cell: 6.5;naive B-cell: 6.4" "Lineage enriched" "Detected in single" 18 "B-cells: 6.5" "Cancer enhanced" "Detected in single" "Leukemia: 1.9" "Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA055919 Approved "Secreted in male reproductive system" Transport NA NA "Cluster 34: B-cells - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 35: RS4;11 - Unknown function" "Cluster 73: B-cells - B-cell function" "HPA055919: AB_2682969" "unprognostic (2.02e-1)" "unprognostic (1.35e-2)" "unprognostic (2.62e-1)" "unprognostic (1.89e-1)" "unprognostic (5.85e-2)" "unprognostic (6.54e-3)" "unprognostic (2.22e-4)" "unprognostic (4.54e-2)" "unprognostic (3.97e-1)" "unprognostic (1.31e-1)" "unprognostic (4.14e-3)" "unprognostic (2.96e-1)" "unprognostic (2.77e-2)" "unprognostic (3.11e-2)" "unprognostic (2.52e-1)" "unprognostic (8.32e-2)" "unprognostic (3.86e-1)" LCN12 MGC48935 ENSG00000184925 "Lipocalin 12" Q6JVE5 9 136949551-136955497 "Predicted intracellular proteins, Predicted secreted proteins" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "epididymis: 77.5" "Cell type enhanced" "Detected in many" "Astrocytes: 18.6;Collecting duct cells: 42.8;Glandular and luminal cells: 53.9;Muller glia cells: 22.8;Secretory cells: 56.6" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 44.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Transport NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 3: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "unprognostic (7.27e-3)" "unprognostic (5.72e-3)" "unprognostic (2.45e-2)" "unprognostic (7.14e-2)" "unprognostic (4.53e-4)" "unprognostic (9.33e-3)" "unprognostic (1.97e-3)" "unprognostic (1.41e-1)" "unprognostic (1.42e-1)" "unprognostic (3.03e-1)" "unprognostic (7.33e-3)" "unprognostic (2.18e-1)" "unprognostic (5.73e-2)" "unprognostic (5.21e-3)" "unprognostic (3.06e-1)" "unprognostic (5.00e-2)" "unprognostic (7.91e-4)" LCN15 "PRO6093, UNQ2541" ENSG00000177984 "Lipocalin 15" Q6UWW0 9 136759634-136766255 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.5;seminal vesicle: 3.2" "Cell type enriched" "Detected in some" 226 "Enteroendocrine cells: 1649.4" "Cancer enriched" "Detected in some" 19 "colorectal cancer: 23.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "colorectal cancer: 15.7;liver cancer: 19.1;lung cancer: 5.9" "Low region specificity" "Detected in all" HPA060584 Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA060584: AB_2684327" "unprognostic (5.24e-1)" "unprognostic (2.61e-1)" "unprognostic (2.14e-1)" "unprognostic (3.67e-1)" "unprognostic (3.45e-2)" "unprognostic (3.28e-2)" "unprognostic (2.39e-1)" "unprognostic (1.83e-1)" LCN2 "24p3, NGAL" ENSG00000148346 "Lipocalin 2" P80188 9 128149071-128153453 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Apoptosis, Immunity, Innate immunity, Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 2741.6;gallbladder: 2147.7;salivary gland: 1269.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4540.1;Club cells: 6415.0;Ductal cells: 6544.0;Exocrine glandular cells: 2381.1;Ionocytes: 7173.7;Mucus glandular cells: 2129.9" "Cancer enhanced" "Detected in many" "stomach cancer: 944.6" "Region enriched" "Detected in single" 5 "choroid plexus: 4.2" "Group enriched" "Detected in some" 88 "basophil: 9.7;neutrophil: 11.9;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 84 "granulocytes: 11.9;monocytes: 4.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 2754.0;pancreatic cancer: 1459.4" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Group enriched" "Detected in all" 6 "cerebellum: 275.8;spinal cord: 180.6" "HPA002695, CAB016549, CAB016550" Enhanced Supported "Endoplasmic reticulum" "Secreted in other tissues" Transport NA NA 297000000 590000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 47 "Endoplasmic reticulum" "CAB016549: , CAB016550: , HPA002695: AB_1852758" "prognostic favorable (9.61e-4)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (7.38e-3)" "unprognostic (1.01e-2)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-1)" "unprognostic (1.79e-1)" "unprognostic (2.36e-2)" "unprognostic (2.83e-2)" "unprognostic (1.10e-3)" "unprognostic (6.15e-2)" "unprognostic (2.37e-1)" "unprognostic (3.15e-2)" "unprognostic (1.11e-2)" LCN6 ENSG00000267206 "Lipocalin 6" P62502 9 136744017-136748525 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 60 "epididymis: 1543.6" "Cell type enriched" "Detected in some" 4 "Endothelial cells: 83.5" "Cancer enriched" "Detected in some" 10 "thyroid cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "Leukemia: 31.7" "Testis - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Other NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 35: RS4;11 - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "unprognostic (4.05e-2)" "unprognostic (1.01e-3)" "unprognostic (1.12e-1)" "unprognostic (5.88e-2)" "unprognostic (3.23e-1)" "unprognostic (1.26e-1)" "unprognostic (3.83e-4)" "unprognostic (3.41e-2)" "unprognostic (7.47e-2)" "unprognostic (1.08e-2)" "unprognostic (2.89e-3)" "unprognostic (1.78e-1)" "unprognostic (5.55e-2)" "unprognostic (2.96e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-1)" LCN8 LCN5 ENSG00000204001 "Lipocalin 8" Q6JVE9 9 136754386-136758543 "Predicted intracellular proteins, Predicted secreted proteins" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 43 "epididymis: 82.0" "Group enriched" "Detected in some" 9 "B-cells: 13.7;Plasma cells: 3.9" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Region enriched" "Detected in single" 7 "cerebellum: 1.8" "Group enriched" "Detected in some" 60 "memory B-cell: 4.1;naive B-cell: 8.2" "Lineage enriched" "Detected in single" 79 "B-cells: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Transport NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 35: Non-specific - DNA binding" "Cluster 6: Leukemia - Signal transduction" "Cluster 73: B-cells - B-cell function" "unprognostic (1.64e-2)" "unprognostic (1.00e-1)" "unprognostic (6.71e-2)" "unprognostic (2.11e-2)" "unprognostic (2.92e-1)" "unprognostic (2.89e-1)" "unprognostic (2.00e-1)" LCN9 ENSG00000148386 "Lipocalin 9" 9 135663309-135666961 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060941 Enhanced "Secreted in male reproductive system" NA NA "Cluster 34: Testis cancer - Unknown function" "HPA060941: AB_2732654" "unprognostic (7.64e-4)" LCORL "FLJ30696, MLR1" ENSG00000178177 "Ligand dependent nuclear receptor corepressor like" Q8N3X6 4 17841187-18021876 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 127.7;Microglial cells: 129.7;Oligodendrocyte precursor cells: 109.9;Oligodendrocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028794, HPA028795, HPA060033" Uncertain Approved "Nucleoplasm,Nuclear membrane" "Intracellular and membrane" Transcription NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 65: Neurons - Synaptic function" 2 Nucleoplasm "Nuclear membrane" "HPA028794: AB_10600664, HPA028795: AB_10600882, HPA060033: AB_2684192" "unprognostic (1.06e-1)" "unprognostic (4.95e-2)" "prognostic favorable (9.65e-4)" "unprognostic (3.22e-3)" "unprognostic (3.62e-2)" "unprognostic (2.54e-4)" "unprognostic (8.90e-4)" "unprognostic (3.46e-1)" "unprognostic (3.52e-2)" "unprognostic (7.59e-2)" "unprognostic (2.10e-1)" "unprognostic (1.22e-1)" "unprognostic (7.39e-2)" "unprognostic (1.70e-2)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (7.27e-4)" LDLRAD2 ENSG00000187942 "Low density lipoprotein receptor class A domain containing 2" Q5SZI1 1 21812265-21825225 "Predicted secreted proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 1.6;Endothelial cells: 2.0;granulocytes: 1.6;Plasma cells: 2.9;Schwann cells: 4.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.2" "Heart muscle - Fibroblasts, Liver - Vascular Endothelial cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "basal ganglia: 5.3;midbrain: 7.9" HPA030478 Approved "Secreted - unknown location" Receptor NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA030478: AB_10601541" "unprognostic (4.16e-2)" "unprognostic (1.22e-1)" "unprognostic (4.13e-2)" "unprognostic (4.21e-2)" "unprognostic (1.78e-1)" "unprognostic (6.22e-3)" "unprognostic (1.35e-2)" "unprognostic (4.85e-2)" "unprognostic (7.52e-2)" "unprognostic (3.80e-2)" "unprognostic (5.34e-2)" "unprognostic (5.38e-2)" "unprognostic (1.04e-3)" "unprognostic (7.39e-3)" "unprognostic (3.14e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" LEAP2 LEAP-2 ENSG00000164406 "Liver enriched antimicrobial peptide 2" Q969E1 5 132873444-132875046 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "liver: 514.5" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 1795.3" "Cancer enriched" "Detected in many" 17 "liver cancer: 40.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted to blood" Defense NA NA 790000 "Cluster 20: Non-specific - DNA binding" "Cluster 83: Liver - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "unprognostic (2.14e-2)" "unprognostic (8.78e-2)" "unprognostic (4.75e-1)" "unprognostic (2.16e-1)" "unprognostic (2.82e-1)" "unprognostic (1.06e-2)" "unprognostic (2.78e-3)" "unprognostic (6.53e-2)" "unprognostic (3.86e-2)" "unprognostic (1.62e-1)" "unprognostic (7.08e-3)" "unprognostic (2.91e-2)" "unprognostic (1.02e-1)" "unprognostic (2.39e-1)" "unprognostic (3.97e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.68e-4)" LECT2 "chm-II, chm2" ENSG00000145826 "Leukocyte cell derived chemotaxin 2" O14960 5 135922279-135954983 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 461.9" "Group enriched" "Detected in some" 22 "Early spermatids: 170.6;Hepatocytes: 115.6;Late spermatids: 59.4" "Cancer enriched" "Detected in single" 216 "liver cancer: 35.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA043883, HPA058246" Enhanced Supported Vesicles,Cytosol "Secreted to blood" Other NA NA 26500000 5300000 "Cluster 31: Liver - Plasma proteins" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 43: Hepatocytes - Metabolism" Cytosol Vesicles "HPA043883: AB_2678714, HPA058246: " "prognostic favorable (4.16e-5)" "unprognostic (2.57e-2)" "unprognostic (3.52e-1)" LEFTY1 "LEFTB, LEFTYB" ENSG00000243709 "Left-right determination factor 1" O75610 1 225886282-225911382 "Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "intestine: 66.4;pancreas: 93.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 65.8;Enteroendocrine cells: 130.4;Glandular and luminal cells: 174.8;Intestinal goblet cells: 67.7;Paneth cells: 231.5;Undifferentiated cells: 258.5" "Group enriched" "Detected in many" 4 "colorectal cancer: 44.8;endometrial cancer: 36.2;pancreatic cancer: 13.8;testis cancer: 15.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 51 "basophil: 16.9" "Lineage enriched" "Detected in single" 51 "granulocytes: 16.9" "Group enriched" "Detected in some" 5 "colorectal cancer: 10.0;Uterine cancer: 4.4" "Colon - Colon enterocytes" "HPA047883, HPA056210" Approved "Secreted in other tissues" Cytokine NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA047883: AB_2680200, HPA056210: AB_2683067" "unprognostic (2.81e-1)" "unprognostic (2.31e-1)" "unprognostic (7.26e-2)" "unprognostic (1.18e-2)" "unprognostic (1.83e-2)" "unprognostic (3.50e-2)" "unprognostic (1.52e-2)" "unprognostic (4.60e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (7.76e-2)" "unprognostic (6.13e-2)" "prognostic unfavorable (2.48e-6)" "unprognostic (2.78e-2)" "unprognostic (1.12e-1)" "unprognostic (2.01e-1)" "unprognostic (2.61e-2)" LEFTY2 "EBAF, LEFTA, LEFTYA, TGFB4" ENSG00000143768 "Left-right determination factor 2" O00292 1 225936598-225941383 "Disease related genes, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 72.1;choroid plexus: 51.7;endometrium 1: 164.7" "Group enriched" "Detected in some" 4 "Early spermatids: 17.9;Endometrial stromal cells: 31.4;Late spermatids: 33.1;Leydig cells: 17.2;Ovarian stromal cells: 28.0;Peritubular cells: 12.7" "Cancer enriched" "Detected in many" 8 "testis cancer: 41.7" "Region enriched" "Detected in some" 20 "choroid plexus: 33.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Myeloma: 17.9;testis cancer: 23.5" "Heart muscle - Fibroblasts, Thyroid - Fibroblasts" "CAB025801, HPA047883, HPA056210" Approved "Secreted in other tissues" Cytokine NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: Endometrial stromal cells - Transcription" "CAB025801: , HPA047883: AB_2680200, HPA056210: AB_2683067" "unprognostic (3.78e-2)" "unprognostic (4.10e-3)" "unprognostic (5.79e-3)" "unprognostic (5.12e-2)" "unprognostic (1.80e-1)" "unprognostic (2.30e-1)" "unprognostic (1.52e-1)" "unprognostic (4.87e-2)" "unprognostic (9.75e-4)" "unprognostic (2.91e-1)" "unprognostic (3.84e-1)" "unprognostic (7.98e-2)" "unprognostic (9.14e-3)" "unprognostic (1.15e-1)" "unprognostic (4.69e-2)" "unprognostic (1.90e-4)" "unprognostic (1.64e-3)" LEP "OB, OBS" ENSG00000174697 Leptin P41159 7 128241278-128257629 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "adipose tissue: 296.7;breast: 87.3" "Group enriched" "Detected in some" 52 "Extravillous trophoblasts: 142.2;Syncytiotrophoblasts: 376.0" "Cancer enhanced" "Detected in some" "breast cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "testis cancer: 2.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Adipocytes (Skin), Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "CAB010490, HPA068565" Approved Approved "Vesicles,Plasma membrane" "Secreted to blood" "No annotated function" NA NA 17000000 19000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 "Vesicles, Plasma membrane" "CAB010490: AB_2296951, HPA068565: " "unprognostic (8.19e-3)" "unprognostic (5.33e-1)" "unprognostic (1.60e-4)" "unprognostic (1.19e-1)" "unprognostic (7.99e-3)" "unprognostic (1.83e-1)" "unprognostic (6.56e-3)" "unprognostic (1.98e-2)" "unprognostic (1.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.23e-2)" "unprognostic (6.84e-2)" LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 126.5" "Cell type enhanced" "Detected in many" "Adipocytes: 97.7;Endothelial cells: 85.6;Fibroblasts: 91.9;Hepatocytes: 137.3;Microglial cells: 123.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 13.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.0" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030899 Approved Supported "Intracellular and membrane" Receptor NA NA 8240000 14000000 "Cluster 33: Non-specific - ATP binding" "Cluster 83: Liver - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 53: Fibroblasts - ECM organization" 2 "HPA030899: AB_10610003" "unprognostic (1.59e-2)" "unprognostic (1.09e-3)" "unprognostic (3.09e-1)" "unprognostic (8.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (2.58e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-3)" "unprognostic (1.79e-1)" "unprognostic (2.41e-1)" "unprognostic (7.53e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" LFNG SCDO3 ENSG00000106003 "LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q8NES3 7 2512529-2529177 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 63.3;skin 1: 56.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 48.2;granulocytes: 62.4;monocytes: 181.7;NK-cells: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 108.5" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069130 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" "Developmental protein" NA NA 880000 "Cluster 25: Non-specific - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus" "Nuclear membrane" "HPA069130: AB_2686091" "unprognostic (4.58e-2)" "unprognostic (1.17e-2)" "unprognostic (2.52e-2)" "prognostic favorable (6.36e-4)" "unprognostic (1.85e-2)" "unprognostic (8.34e-2)" "unprognostic (4.15e-1)" "unprognostic (7.86e-2)" "unprognostic (1.91e-1)" "unprognostic (2.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.89e-1)" "unprognostic (5.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.09e-1)" "unprognostic (1.97e-2)" "unprognostic (2.28e-2)" LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial stromal cells: 3194.1;Hofbauer cells: 4231.1;Langerhans cells: 5027.3;Pancreatic endocrine cells: 4019.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 2024.9" "HPA000646, HPA001130, CAB002157" Enhanced Supported Cytosol "Secreted to blood" Other No Yes 10000000 20000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 15: Non-specific - Mixed function" 9 Cytosol "CAB002157: AB_563734, HPA000646: AB_1078935, HPA001130: AB_2756311" "unprognostic (1.65e-1)" "unprognostic (8.13e-2)" "unprognostic (5.13e-2)" "prognostic favorable (2.36e-5)" "unprognostic (6.38e-2)" "unprognostic (2.67e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.22e-3)" "unprognostic (4.91e-3)" "unprognostic (2.51e-1)" "unprognostic (6.16e-3)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.18e-10)" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (5.10e-4)" LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1154.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 8373.5;Paneth cells: 4392.4;Proximal enterocytes: 4885.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 652.7;intermediate monocyte: 545.4;myeloid DC: 398.3;non-classical monocyte: 443.7;T-reg: 252.7" "Group enriched" "Detected in all" 13 "dendritic cells: 398.3;monocytes: 652.7;T-cells: 252.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA NA 1900000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 13 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: AB_2136784, HPA003162: AB_1078937, HPA076528: " "unprognostic (1.42e-1)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.73e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-3)" "unprognostic (5.97e-2)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.96e-2)" "unprognostic (2.65e-3)" "unprognostic (7.60e-3)" LGALS3BP "90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B" ENSG00000108679 "Galectin 3 binding protein" Q08380 17 78971238-78979947 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 533.0;Proximal enterocytes: 869.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "monocytes: 27.2;T-cells: 68.6" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000410, HPA000554" Uncertain "Secreted to blood" "Cell adhesion" NA NA 7100000000 "Cluster 11: T-cells - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 5: Enterocytes - Absorption" 6 "HPA000410: , HPA000554: AB_1079246" "unprognostic (1.23e-2)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.63e-3)" "unprognostic (1.62e-2)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (1.57e-2)" "unprognostic (4.55e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (1.58e-1)" "unprognostic (1.65e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" LGALS7 "GAL7, LGALS7A, PIG1, TP53I1" ENSG00000205076 "Galectin 7" P47929 19 38770968-38773517 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 382.0;skin 1: 850.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 244.4;Basal squamous epithelial cells: 204.8;Squamous epithelial cells: 703.2;Suprabasal keratinocytes: 1071.6" "Group enriched" "Detected in many" 7 "cervical cancer: 32.0;head and neck cancer: 64.8;melanoma: 27.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Esophageal cancer: 12.5;head and neck cancer: 28.3" "HPA001549, CAB032606" Enhanced "Intracellular and membrane" Other NA NA 4000000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 6 "CAB032606: AB_640852, HPA001549: AB_1078938" "unprognostic (1.56e-2)" "unprognostic (1.30e-2)" "unprognostic (1.18e-2)" "unprognostic (4.86e-2)" "unprognostic (2.39e-1)" "unprognostic (2.38e-1)" "unprognostic (2.35e-1)" "unprognostic (1.05e-2)" "unprognostic (9.01e-2)" "unprognostic (3.37e-1)" "unprognostic (1.93e-1)" "unprognostic (3.31e-2)" "unprognostic (3.09e-2)" LGALS7B GAL7 ENSG00000178934 "Galectin 7B" P47929 19 38789200-38791754 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6489.8" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 1317.5;Suprabasal keratinocytes: 2899.8" "Cancer enhanced" "Detected in many" "cervical cancer: 142.7;head and neck cancer: 185.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.3;head and neck cancer: 2.3;liver cancer: 1.9" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "HPA001549, CAB025100" Supported "Intracellular and membrane" Other NA NA 4000000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 6 "CAB025100: , HPA001549: AB_1078938" "unprognostic (4.20e-2)" "unprognostic (2.15e-1)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.81e-1)" "unprognostic (3.54e-2)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (5.92e-2)" "unprognostic (3.66e-3)" "unprognostic (6.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.20e-2)" "unprognostic (1.29e-3)" LGALS9 LGALS9A ENSG00000168961 "Galectin 9" O00182 17 27629798-27649560 "Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 95.8;stomach 1: 85.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 188.2;Gastric mucus-secreting cells: 163.9;Hofbauer cells: 314.6;Intestinal goblet cells: 172.3;Kupffer cells: 213.0;Macrophages: 160.4;monocytes: 222.0;Paneth cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 66.9" "Lung - Macrophages, Stomach - Gastric mucous cells" "HPA046876, HPA047218, CAB080347" Approved Supported Cytosol "Secreted to blood" Immunity NA NA 448000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" Cytosol "CAB080347: , HPA046876: AB_2679852, HPA047218: AB_2679988" "unprognostic (2.62e-2)" "prognostic favorable (2.35e-5)" "unprognostic (1.16e-2)" "unprognostic (3.57e-1)" "unprognostic (2.01e-1)" "unprognostic (2.46e-3)" "unprognostic (1.58e-2)" "unprognostic (8.60e-2)" "unprognostic (4.79e-1)" "unprognostic (1.80e-1)" "unprognostic (8.13e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (4.76e-2)" "unprognostic (3.02e-2)" "unprognostic (2.23e-2)" "unprognostic (2.24e-3)" LGI1 "EPITEMPIN, EPT, ETL1, IB1099" ENSG00000108231 "Leucine rich glioma inactivated 1" O95970 10 93757840-93806272 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 46.6;choroid plexus: 70.6" "Cell type enhanced" "Detected in some" "Astrocytes: 230.4;Excitatory neurons: 55.2;Inhibitory neurons: 71.4;Oligodendrocyte precursor cells: 26.9" "Group enriched" "Detected in some" 7 "glioma: 1.8;testis cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0;Rhabdoid: 6.2;testis cancer: 3.1" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" "No annotated function" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 47: Astrocytes - Unknown function" "unprognostic (1.26e-1)" "unprognostic (4.68e-2)" "unprognostic (2.45e-2)" "unprognostic (1.01e-1)" "unprognostic (8.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.24e-3)" "unprognostic (1.85e-1)" "unprognostic (4.07e-3)" "unprognostic (8.71e-2)" "unprognostic (2.21e-1)" "unprognostic (5.93e-2)" "unprognostic (4.65e-1)" LGI2 "FLJ10675, KIAA1916" ENSG00000153012 "Leucine rich repeat LGI family member 2" Q8N0V4 4 24998847-25030946 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "parathyroid gland: 123.8" "Cell type enhanced" "Detected in some" "Horizontal cells: 13.8;Inhibitory neurons: 32.0;Oligodendrocyte precursor cells: 9.4;Oocytes: 8.8;Smooth muscle cells: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017140 Approved Uncertain Centrosome "Secreted to blood" "No annotated function" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 69: Neurons - Neuronal signaling" Centrosome "HPA017140: AB_1852833" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (4.31e-2)" "unprognostic (1.20e-5)" "unprognostic (3.99e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-2)" "unprognostic (8.54e-2)" "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (3.47e-2)" "unprognostic (1.62e-1)" "unprognostic (9.38e-5)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (2.06e-4)" "unprognostic (5.03e-3)" LGI3 ENSG00000168481 "Leucine rich repeat LGI family member 3" Q8N145 8 22146830-22157084 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Exocytosis "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 95.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 46.7;Excitatory neurons: 17.1;Horizontal cells: 17.6;Inhibitory neurons: 22.8;Melanocytes: 77.3;Oligodendrocytes: 54.4" "Group enriched" "Detected in many" 5 "glioma: 4.7;melanoma: 14.3;thyroid cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 28 "skin cancer: 13.5" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" Other NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Alveolar cells - Lung function" "unprognostic (4.41e-2)" "unprognostic (1.78e-1)" "unprognostic (3.28e-1)" "unprognostic (8.11e-3)" "unprognostic (1.14e-1)" "unprognostic (7.45e-2)" "unprognostic (3.38e-1)" "unprognostic (2.43e-2)" "unprognostic (9.64e-2)" "unprognostic (1.64e-2)" "unprognostic (6.25e-3)" "unprognostic (1.26e-2)" "unprognostic (5.59e-5)" "unprognostic (1.36e-2)" "unprognostic (9.41e-2)" "unprognostic (4.80e-2)" "unprognostic (4.14e-2)" LGI4 ENSG00000153902 "Leucine rich repeat LGI family member 4" Q8N135 19 35124513-35142451 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Schwann cells: 451.4" "Group enriched" "Detected in many" 6 "glioma: 4.5;melanoma: 11.5;renal cancer: 13.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.4;skin cancer: 3.7" "Colon - Enteric glia cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042116, HPA043556" Approved Approved "Golgi apparatus" "Secreted in brain" "No annotated function" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Golgi apparatus" "HPA042116: AB_2677855, HPA043556: AB_2678550" "unprognostic (3.79e-1)" "unprognostic (6.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-2)" "unprognostic (3.71e-2)" "unprognostic (2.12e-2)" "unprognostic (4.26e-2)" "unprognostic (4.57e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.84e-7)" "unprognostic (1.71e-2)" "unprognostic (4.47e-1)" "unprognostic (7.73e-2)" "unprognostic (7.13e-2)" LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748679 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1263.9;Syncytiotrophoblasts: 507.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 209.4" "Lineage enriched" "Detected in all" 12 "dendritic cells: 209.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001426: AB_1079247" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.47e-1)" "prognostic favorable (4.70e-4)" "unprognostic (8.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.18e-3)" "unprognostic (7.24e-2)" LHB "CGB4, hLHB, LSH-B" ENSG00000104826 "Luteinizing hormone subunit beta" P01229 19 49015980-49017091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 249 "pituitary gland: 4374.0" "Cell type enhanced" "Detected in some" "Early spermatids: 4.7;Late spermatids: 4.7;Melanocytes: 3.4;Oocytes: 3.7;Syncytiotrophoblasts: 10.2" "Cancer enhanced" "Detected in many" "melanoma: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "CAB022241, CAB022707, HPA038925" Enhanced "Secreted to blood" Hormone NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 2 "CAB022241: , CAB022707: , HPA038925: AB_2676272" "unprognostic (8.12e-2)" "unprognostic (3.59e-1)" "unprognostic (2.34e-3)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (5.69e-2)" "unprognostic (7.04e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (6.78e-4)" "unprognostic (2.47e-2)" "unprognostic (1.68e-3)" "unprognostic (1.38e-1)" "unprognostic (4.46e-1)" "unprognostic (9.52e-2)" "unprognostic (4.86e-2)" LIF "CDF, DIA, HILDA" ENSG00000128342 "LIF interleukin 6 family cytokine" P15018 22 30240453-30246759 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 46.1;urinary bladder: 87.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 97.2;Glandular and luminal cells: 177.8;granulocytes: 147.2;Ionocytes: 278.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "choroid plexus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018844, CAB025985" Uncertain Supported Cytosol "Secreted in other tissues" Cytokine NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 5 Cytosol "CAB025985: , HPA018844: AB_1852814" "unprognostic (1.28e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (8.79e-2)" "unprognostic (4.61e-2)" "unprognostic (7.36e-3)" "unprognostic (4.18e-3)" "unprognostic (1.17e-2)" "unprognostic (1.41e-2)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (6.78e-8)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (8.99e-2)" "unprognostic (4.71e-3)" LIFR CD118 ENSG00000113594 "LIF receptor subunit alpha" P42702 5 38474668-38608354 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 337.3;Astrocytes: 357.3;Endothelial cells: 362.2;Oligodendrocytes: 256.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA 260000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "unprognostic (6.00e-3)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (2.81e-3)" "unprognostic (8.80e-2)" "unprognostic (7.13e-2)" "unprognostic (1.11e-1)" "prognostic favorable (1.92e-4)" "unprognostic (1.78e-1)" "unprognostic (9.80e-2)" "unprognostic (2.73e-3)" "unprognostic (1.06e-1)" "prognostic favorable (1.40e-7)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-2)" "unprognostic (1.65e-1)" LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.2;lymphoid tissue: 55.9" "Group enriched" "Detected in some" 8 "Hofbauer cells: 51.9;Kupffer cells: 73.3;Macrophages: 38.9;monocytes: 101.0" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 31.8" "Group enriched" "Detected in many" 6 "granulocytes: 31.8;monocytes: 11.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.6" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Neutrophil_2, Pancreas - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Secreted to blood" Receptor NA NA 140000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 29: Monocytes - Innate immune response" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" LILRA5 "CD85, CD85f, ILT11, LILRB7, LIR9" ENSG00000187116 "Leukocyte immunoglobulin like receptor A5" A6NI73 19 54307070-54313166 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.4;lymphoid tissue: 74.5" "Cell type enriched" "Detected in some" 8 "monocytes: 824.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "classical monocyte: 128.6;intermediate monocyte: 252.9;neutrophil: 137.5;non-classical monocyte: 312.7" "Group enriched" "Detected in many" 6 "granulocytes: 137.5;monocytes: 312.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Secreted to blood" Receptor NA NA 670000 "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "unprognostic (8.52e-2)" "unprognostic (3.61e-1)" "unprognostic (2.23e-1)" "unprognostic (1.77e-1)" "unprognostic (1.57e-2)" "unprognostic (6.56e-2)" "unprognostic (2.90e-1)" "unprognostic (1.86e-1)" "unprognostic (3.11e-1)" "unprognostic (6.61e-3)" "unprognostic (2.01e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (3.61e-2)" "unprognostic (6.51e-3)" "unprognostic (4.68e-2)" "unprognostic (6.21e-2)" LILRB1 "CD85, CD85j, ILT2, LIR-1, LIR1, MIR-7, PIR-B, PIRB" ENSG00000104972 "Leukocyte immunoglobulin like receptor B1" 19 54617158-54638022 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 35.3" "Cell type enhanced" "Detected in some" "dendritic cells: 58.5;Hofbauer cells: 29.3;Kupffer cells: 72.5;Macrophages: 67.3;Microglial cells: 29.5;monocytes: 226.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 52.6;non-classical monocyte: 74.2" "Lineage enriched" "Detected in many" 11 "monocytes: 74.2" "Group enriched" "Detected in some" 40 "Leukemia: 2.3;lymphoma: 6.1;Myeloma: 3.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Liver - Kupffer cells, Prostate - T-cells, Stomach - Macrophages" "Intracellular and membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" "unprognostic (9.23e-2)" "unprognostic (4.20e-2)" "unprognostic (4.95e-2)" "unprognostic (3.29e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-2)" "unprognostic (1.24e-1)" "unprognostic (3.89e-2)" "unprognostic (3.58e-1)" "unprognostic (9.64e-2)" "unprognostic (1.24e-1)" "unprognostic (5.92e-2)" "prognostic unfavorable (3.08e-6)" "unprognostic (6.57e-2)" "unprognostic (1.62e-2)" "unprognostic (7.06e-2)" "unprognostic (8.03e-2)" LIME1 "dJ583P15.4, FLJ20406, LIME" ENSG00000203896 "Lck interacting transmembrane adaptor 1" Q9H400 20 63736283-63739103 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 237.0" "Cell type enhanced" "Detected in some" "Astrocytes: 20.4;Gastric mucus-secreting cells: 21.2;Plasma cells: 134.1;T-cells: 34.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 315.5;MAIT T-cell: 285.7;memory CD4 T-cell: 438.9;memory CD8 T-cell: 412.4;naive CD4 T-cell: 290.2;naive CD8 T-cell: 320.3;plasmacytoid DC: 750.7;T-reg: 691.2" "Group enriched" "Detected in all" 8 "dendritic cells: 750.7;T-cells: 691.2" "Cancer enriched" "Detected in many" 9 "Myeloma: 158.1" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Not detected" "Not detected" CAB015363 Approved "Intracellular and membrane" Immunity NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 83: Liver - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: T-cells - T-cell receptor" 37 "CAB015363: AB_629890" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (5.95e-3)" "unprognostic (3.01e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-3)" "unprognostic (3.06e-2)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (1.94e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-3)" "prognostic unfavorable (5.04e-5)" "unprognostic (2.39e-2)" "unprognostic (4.25e-2)" "unprognostic (1.67e-1)" "prognostic favorable (6.92e-6)" LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 388.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 457.6;Kupffer cells: 634.6;Macrophages: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.7;intermediate monocyte: 355.8;myeloid DC: 123.8;non-classical monocyte: 199.7" "Group enriched" "Detected in all" 6 "dendritic cells: 123.8;monocytes: 355.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA 280000 "Cluster 40: Monocytes - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" LIPC "HL, HTGL" ENSG00000166035 "Lipase C, hepatic type" P11150 15 58410569-58569844 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "liver: 165.9" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 149.3" "Group enriched" "Detected in some" 14 "liver cancer: 20.4;renal cancer: 10.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "granulocytes: 1.7;NK-cells: 1.5;T-cells: 1.8" "Group enriched" "Detected in many" 5 "Gastric cancer: 22.7;Kidney cancer: 6.3;liver cancer: 18.6" "Liver - Hepatocytes, Skin - Fibroblast_1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" Enzyme NA NA 5500000 "Cluster 33: Non-specific - ATP binding" "Cluster 31: Liver - Plasma proteins" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "unprognostic (1.76e-2)" "unprognostic (9.15e-3)" "unprognostic (7.89e-2)" "unprognostic (7.15e-4)" "unprognostic (1.40e-1)" "unprognostic (1.33e-2)" "unprognostic (9.93e-3)" "unprognostic (6.25e-2)" "unprognostic (3.79e-2)" "unprognostic (1.10e-2)" "unprognostic (3.06e-1)" "unprognostic (2.31e-1)" "unprognostic (2.82e-2)" "unprognostic (1.41e-1)" "unprognostic (2.87e-2)" "unprognostic (1.80e-2)" "unprognostic (2.27e-2)" LIPF "HGL, HLAL" ENSG00000182333 "Lipase F, gastric type" P07098 10 88664441-88678814 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 142 "stomach 1: 36201.8" "Cell type enriched" "Detected in some" 316 "Gastric mucus-secreting cells: 1628.3" "Cancer enriched" "Detected in some" 75 "stomach cancer: 278.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Chief cells" "Region enriched" "Detected in single" 77 "olfactory bulb: 7.6" HPA045930 Enhanced "Secreted to digestive system" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 27: Breast cancer - Unknown function" "Cluster 46: Gastric mucus-secreting cells - Digestion" "HPA045930: AB_10959518" "unprognostic (1.53e-1)" "unprognostic (1.83e-1)" LIPG EDL ENSG00000101670 "Lipase G, endothelial type" Q9Y5X9 18 49560699-49599185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "placenta: 144.4;thyroid gland: 235.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 25.5;Extravillous trophoblasts: 73.5;Glandular and luminal cells: 35.0;Hepatocytes: 61.8;Syncytiotrophoblasts: 29.5" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 20.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016966 Uncertain "Secreted to blood" Enzyme NA NA 657000000 810000 "Cluster 58: Placenta - Pregnancy" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 50: Connective tissue cells - ECM organization" "HPA016966: AB_1852893" "unprognostic (2.20e-2)" "unprognostic (3.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.25e-3)" "unprognostic (6.38e-2)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" "unprognostic (4.55e-3)" "unprognostic (9.93e-2)" "unprognostic (1.44e-1)" "unprognostic (6.44e-2)" "unprognostic (8.74e-2)" "unprognostic (2.98e-1)" "unprognostic (8.68e-2)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (1.35e-1)" LIPH "LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B" ENSG00000163898 "Lipase H" Q8WWY8 3 185506262-185552588 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.5;stomach 1: 47.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 152.9;Gastric mucus-secreting cells: 172.1;Granulosa cells: 101.5;Intestinal goblet cells: 159.8;Ionocytes: 397.6;Proximal enterocytes: 138.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 39.7;pancreatic cancer: 33.3" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA049079 Approved "Secreted to blood" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA049079: AB_2680623" "unprognostic (4.50e-3)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (3.38e-1)" "unprognostic (1.01e-1)" "unprognostic (8.59e-2)" "unprognostic (1.44e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (7.88e-2)" "prognostic favorable (9.20e-5)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (4.21e-4)" "unprognostic (1.15e-1)" LIPI "CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5" ENSG00000188992 "Lipase I" Q6XZB0 21 14108813-14210955 "Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 169 "epididymis: 409.2" "Cell type enhanced" "Detected in some" "Early spermatids: 2.0;Excitatory neurons: 1.5;Inhibitory neurons: 1.9;Microglial cells: 1.8;Oligodendrocyte precursor cells: 1.9" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 54 "Bone cancer: 22.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA049665 Supported "Plasma membrane" "Secreted in male reproductive system" Enzyme NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" "HPA049665: " "unprognostic (2.60e-2)" "unprognostic (3.49e-1)" "unprognostic (1.12e-3)" "unprognostic (1.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.68e-1)" "unprognostic (4.53e-2)" "unprognostic (2.90e-1)" "unprognostic (3.64e-13)" "unprognostic (2.82e-1)" "unprognostic (4.14e-2)" "unprognostic (2.90e-1)" "unprognostic (7.87e-3)" LIPK "bA186O14.2, LIPL2" ENSG00000204021 "Lipase family member K" Q5VXJ0 10 88706249-88752776 "Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 28.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (other), Stomach - Chief cells" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "unprognostic (7.65e-2)" "unprognostic (8.64e-2)" "unprognostic (3.57e-2)" "unprognostic (3.19e-7)" "unprognostic (1.25e-1)" "unprognostic (1.60e-2)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" LIPM "bA304I5.1, LIPL3" ENSG00000173239 "Lipase family member M" Q5VYY2 10 88802730-88820546 "Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "skin 1: 27.3" "Cell type enhanced" "Detected in single" "Mesothelial cells: 2.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071276 Approved "Endoplasmic reticulum" "Secreted in other tissues" Enzyme NA NA "Cluster 13: Skin - Cornification" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 12: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum" "HPA071276: " "unprognostic (7.72e-2)" "unprognostic (8.49e-4)" "unprognostic (1.42e-2)" "unprognostic (2.23e-4)" "unprognostic (6.70e-3)" "unprognostic (3.01e-3)" "unprognostic (5.75e-2)" "unprognostic (6.63e-2)" "unprognostic (5.61e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (6.47e-4)" "unprognostic (1.59e-2)" "unprognostic (5.93e-2)" "unprognostic (7.05e-3)" "unprognostic (4.17e-2)" "unprognostic (9.02e-2)" "unprognostic (9.70e-6)" LIPN "bA186O14.3, LIPL4" ENSG00000204020 "Lipase family member N" Q5VXI9 10 88759982-88779626 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 26.0" "Cell type enriched" "Detected in some" 8 "monocytes: 186.5" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 2.9;eosinophil: 10.3;intermediate monocyte: 7.5;neutrophil: 5.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 8 "granulocytes: 10.3;monocytes: 8.5" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" Enzyme NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 82: Skin - Keratinization" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.27e-1)" "unprognostic (1.07e-1)" "unprognostic (2.03e-2)" "unprognostic (9.75e-2)" "unprognostic (2.54e-2)" "unprognostic (4.40e-2)" "unprognostic (5.77e-3)" "unprognostic (1.65e-1)" LLCFC1 "C7orf34, CTM-1" ENSG00000165131 "LLLL and CFNLAS motif containing 1" Q96L11 7 142939343-142940868 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 40 "testis: 64.2" "Group enriched" "Detected in some" 68 "Early spermatids: 453.3;Late spermatids: 299.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Other NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Early spermatids - Unknown function" "unprognostic (5.05e-2)" "unprognostic (9.94e-2)" "unprognostic (5.49e-3)" "unprognostic (2.76e-2)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (2.23e-2)" "unprognostic (1.85e-3)" "unprognostic (3.54e-1)" "unprognostic (2.02e-1)" LNPEP "CAP, IRAP, P-LAP, PLAP" ENSG00000113441 "Leucyl and cystinyl aminopeptidase" Q9UIQ6 5 96935394-97037513 "Enzymes, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 187.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043642 Approved "Intracellular and membrane" Enzyme NA NA 9800000 "Cluster 32: Basophils - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 19: NK-cells - Adaptive immune response" 4 "HPA043642: AB_10964137" "unprognostic (1.52e-1)" "unprognostic (5.39e-2)" "unprognostic (7.78e-2)" "unprognostic (1.53e-2)" "unprognostic (6.38e-2)" "unprognostic (6.59e-3)" "unprognostic (6.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.11e-1)" "unprognostic (3.54e-3)" "unprognostic (6.24e-2)" "unprognostic (2.08e-1)" "unprognostic (3.28e-1)" "unprognostic (4.13e-3)" "unprognostic (1.46e-1)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" LNX1 "LNX, MPDZ, PDZRN2" ENSG00000072201 "Ligand of numb-protein X 1" Q8TBB1 4 53459301-53701405 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 69.7;Early spermatids: 218.6;Excitatory neurons: 119.8;Glandular and luminal cells: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002235, HPA071091" Approved Supported "Cell Junctions,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 34: Neurons - Neuronal signaling" 333 "Cell Junctions" Cytosol "HPA002235: AB_1079261, HPA071091: AB_2686344" "unprognostic (4.95e-2)" "unprognostic (1.74e-2)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (2.79e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (5.62e-2)" "unprognostic (8.14e-2)" "unprognostic (1.06e-1)" "unprognostic (5.18e-2)" "unprognostic (8.56e-2)" "prognostic favorable (3.08e-7)" "unprognostic (2.67e-1)" "unprognostic (5.49e-2)" "unprognostic (6.81e-2)" "unprognostic (3.05e-2)" LOX ENSG00000113083 "Lysyl oxidase" P28300 5 122063195-122078413 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 27.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.4;Early spermatids: 50.4;Extravillous trophoblasts: 48.8;Fibroblasts: 84.4;Lymphatic endothelial cells: 146.7;Mesothelial cells: 57.0;Pancreatic endocrine cells: 124.0" "Cancer enhanced" "Detected in all" "renal cancer: 39.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 80.9;Kidney cancer: 81.9" "Heart muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043930 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" Enzyme NA NA 550000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 5 "Endoplasmic reticulum" "HPA043930: AB_2678736" "unprognostic (5.10e-2)" "unprognostic (1.03e-2)" "unprognostic (6.99e-3)" "unprognostic (3.64e-2)" "unprognostic (9.86e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.42e-3)" "unprognostic (3.06e-3)" "unprognostic (8.92e-2)" "unprognostic (3.21e-3)" "unprognostic (1.91e-1)" "prognostic unfavorable (3.93e-8)" "unprognostic (1.11e-3)" "unprognostic (9.92e-2)" "unprognostic (4.31e-2)" "prognostic unfavorable (3.32e-4)" LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 173.8;Fibroblasts: 58.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 26.2" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cancer enhanced" "Detected in many" "Brain cancer: 89.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Colon - Smooth muscle cells, Liver - Hepatic stellate cells, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" Enzyme No No 280000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA042111: AB_10794412, HPA063583: AB_2685050" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (3.05e-2)" "unprognostic (3.61e-2)" "prognostic unfavorable (9.52e-5)" "unprognostic (7.95e-2)" "unprognostic (2.49e-1)" "unprognostic (2.44e-1)" "unprognostic (3.10e-1)" "unprognostic (1.57e-1)" "unprognostic (1.63e-1)" "unprognostic (9.83e-2)" "unprognostic (1.14e-3)" "unprognostic (4.51e-2)" "unprognostic (5.81e-2)" "unprognostic (1.41e-2)" "unprognostic (9.76e-2)" LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 39.7" "Cell type enriched" "Detected in many" 6 "Oocytes: 241.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Kidney cancer: 665.7" "Breast - Adipocytes (Breast), Skeletal muscle - Fibroblasts, Thyroid - Endothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" Transcription NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 4 Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" LOXL3 ENSG00000115318 "Lysyl oxidase like 3" P58215 2 74532258-74555690 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Oxidoreductase "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 13.3;Hofbauer cells: 17.2;Macrophages: 10.2;Melanocytes: 10.3;Microglial cells: 28.6;monocytes: 10.4;Oligodendrocyte precursor cells: 10.8;Pancreatic endocrine cells: 11.9;Sertoli cells: 10.9" "Cancer enhanced" "Detected in many" "melanoma: 15.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 11.7;non-classical monocyte: 9.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Rhabdoid: 94.7;skin cancer: 164.6" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035281 Approved "Secreted to extracellular matrix" Enzyme NA NA 200000 "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "HPA035281: AB_10601766" "unprognostic (7.54e-2)" "unprognostic (2.53e-2)" "unprognostic (5.34e-3)" "unprognostic (4.55e-3)" "unprognostic (6.85e-2)" "unprognostic (1.96e-1)" "unprognostic (1.68e-3)" "unprognostic (6.84e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.22e-2)" "unprognostic (7.33e-3)" "unprognostic (7.09e-2)" "unprognostic (3.38e-2)" LOXL4 "FLJ21889, LOXC" ENSG00000138131 "Lysyl oxidase like 4" Q96JB6 10 98247690-98268194 "Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 134.1;Collecting duct cells: 33.1;Pancreatic endocrine cells: 30.6;Salivary duct cells: 47.3;Skeletal myocytes: 31.2" "Cancer enhanced" "Detected in all" "melanoma: 44.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "skin cancer: 160.0" "Lung - Fibroblast_1, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB033876, HPA037609" Approved Approved Vesicles "Secreted to extracellular matrix" Enzyme NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Respiratory epithelial cells - Unknown function" 15 Vesicles "CAB033876: AB_2135101, HPA037609: AB_2675579" "unprognostic (9.91e-3)" "unprognostic (3.97e-2)" "unprognostic (1.81e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (7.71e-2)" "unprognostic (1.75e-2)" "unprognostic (8.38e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.57e-4)" "unprognostic (2.51e-1)" "unprognostic (4.97e-2)" "unprognostic (5.25e-2)" "unprognostic (5.77e-3)" "unprognostic (1.28e-1)" "unprognostic (6.10e-2)" "unprognostic (7.40e-3)" LPA "LP, Lp(a)" ENSG00000198670 Lipoprotein(a) P08519 6 160531482-160664275 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid transport, Transport" "Hydrolase, Protease, Serine protease" Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 65 "liver: 74.5" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 34.5" "Cancer enriched" "Detected in single" 38 "liver cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "CAB016072, HPA060604" Supported "Secreted to blood" Transport NA NA 78800000000 1800000000 "Cluster 31: Liver - Plasma proteins" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 62: Hepatocytes - Metabolism" 2 "CAB016072: AB_2135240, HPA060604: AB_2684330" "unprognostic (2.16e-1)" "unprognostic (5.10e-1)" "unprognostic (7.75e-3)" "unprognostic (6.70e-2)" "unprognostic (1.60e-1)" "unprognostic (4.17e-3)" "unprognostic (1.59e-1)" "unprognostic (6.38e-3)" "unprognostic (3.63e-2)" "unprognostic (3.18e-1)" "unprognostic (7.45e-3)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (3.72e-2)" LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 904.9;heart muscle: 394.5" "Cell type enhanced" "Detected in many" "Adipocytes: 404.3;Breast glandular cells: 110.6;Cardiomyocytes: 655.2;Schwann cells: 154.4" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Region enhanced" "Detected in all" "basal ganglia: 106.9" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cancer enhanced" "Detected in many" "cervical cancer: 15.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Adipocytes (Skin), Testis - Endothelial cells" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 4 "basal ganglia: 101.9;spinal cord: 74.2" HPA048749 Supported Vesicles "Secreted to blood" Enzyme NA NA 4200000 "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 17: Breast glandular cells - Lactation" 9 Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" LPO SPO ENSG00000167419 Lactoperoxidase P22079 17 58218548-58268518 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Antimicrobial, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 847 "salivary gland: 998.8" "Cell type enriched" "Detected in some" 37 "Serous glandular cells: 1096.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "midbrain: 5.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.4" "Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028688 Enhanced Supported "Secreted to digestive system" Enzyme NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA028688: AB_10601909" "unprognostic (2.74e-1)" "unprognostic (5.12e-2)" "unprognostic (4.14e-3)" "unprognostic (1.56e-3)" "unprognostic (2.41e-2)" "unprognostic (9.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (2.40e-2)" "unprognostic (6.27e-3)" "unprognostic (6.32e-2)" "unprognostic (2.56e-1)" "unprognostic (0.00e+0)" "unprognostic (3.41e-2)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (1.22e-1)" LRCH3 MGC4126 ENSG00000186001 "Leucine rich repeats and calponin homology domain containing 3" Q96II8 3 197791226-197888436 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 95.7;Oligodendrocytes: 129.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012380, HPA017299" Uncertain Enhanced Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 32: Basophils - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" 1 Cytosol "HPA012380: AB_1853260, HPA017299: AB_2669576" "unprognostic (1.25e-1)" "unprognostic (4.92e-1)" "unprognostic (1.43e-1)" "unprognostic (2.69e-3)" "unprognostic (1.05e-1)" "unprognostic (8.26e-2)" "prognostic unfavorable (2.95e-4)" "unprognostic (3.29e-1)" "unprognostic (4.13e-1)" "unprognostic (9.85e-2)" "unprognostic (1.64e-1)" "unprognostic (2.06e-2)" "unprognostic (1.79e-3)" "unprognostic (3.29e-2)" "unprognostic (2.67e-1)" "unprognostic (5.59e-2)" "unprognostic (1.32e-1)" LRCOL1 ENSG00000204583 "Leucine rich colipase like 1" A6NCL2 12 132603150-132610582 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "epididymis: 48.9" "Group enriched" "Detected in some" 5 "Hepatocytes: 27.5;Lymphatic endothelial cells: 22.0" "Group enriched" "Detected in some" 4 "endometrial cancer: 0.8;liver cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Fibroblasts" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 70: DU4475 - Unknown function" "Cluster 62: Hepatocytes - Metabolism" "unprognostic (5.09e-3)" "unprognostic (7.83e-3)" "unprognostic (3.26e-1)" "unprognostic (6.94e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-2)" "prognostic favorable (7.04e-4)" "unprognostic (4.54e-2)" "unprognostic (6.08e-2)" "unprognostic (5.29e-2)" "unprognostic (4.66e-3)" "unprognostic (1.52e-1)" "unprognostic (6.50e-6)" "unprognostic (1.46e-3)" "unprognostic (9.63e-2)" "unprognostic (3.31e-1)" "unprognostic (4.00e-3)" LRFN5 "C14orf146, FIGLER8, SALM5" ENSG00000165379 "Leucine rich repeat and fibronectin type III domain containing 5" Q96NI6 14 41606876-41904549 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7;cervix: 9.8;parathyroid gland: 10.8" "Group enriched" "Detected in some" 13 "Excitatory neurons: 845.2;Inhibitory neurons: 558.1;Oligodendrocyte precursor cells: 277.8" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.8;Sarcoma: 3.2" "Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001177 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "HPA001177: AB_1079274" "unprognostic (5.23e-3)" "unprognostic (1.37e-1)" "unprognostic (5.10e-1)" "unprognostic (6.24e-2)" "unprognostic (2.39e-1)" "unprognostic (3.54e-1)" "unprognostic (1.31e-1)" "unprognostic (6.38e-3)" "unprognostic (2.61e-2)" "unprognostic (5.78e-2)" "unprognostic (2.70e-2)" "unprognostic (9.27e-2)" "unprognostic (6.02e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (6.07e-3)" "unprognostic (2.92e-3)" LRG1 LRG ENSG00000171236 "Leucine rich alpha-2-glycoprotein 1" P02750 19 4536402-4540036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "liver: 920.6" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 621.6" "Cancer enriched" "Detected in many" 9 "liver cancer: 160.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 19 "neutrophil: 285.0" "Lineage enriched" "Detected in many" 45 "granulocytes: 285.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils" "Low region specificity" "Detected in single" "HPA001888, HPA001889" Enhanced Approved Vesicles "Secreted to blood" "No annotated function" NA NA 21000000000 42000000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Hepatocytes - Metabolism" 1 Vesicles "HPA001888: AB_1079276, HPA001889: AB_1079275" "unprognostic (5.54e-3)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (1.42e-1)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (1.46e-3)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.66e-6)" "unprognostic (4.06e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.49e-4)" "unprognostic (2.60e-2)" LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Host-virus interaction" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 105.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 328.0;Leydig cells: 229.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.5" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" Receptor NA NA 180000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 7 Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" LRP8 "APOER2, HSZ75190, LRP-8, MCI1" ENSG00000157193 "LDL receptor related protein 8" Q14114 1 53242364-53328469 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.3;thyroid gland: 40.3" "Cell type enhanced" "Detected in many" "Astrocytes: 29.1;Bipolar cells: 40.2;Excitatory neurons: 34.7;Horizontal cells: 50.4;Inhibitory neurons: 111.8;Microglial cells: 41.2;Sertoli cells: 35.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073031 Enhanced "Secreted in other tissues" Receptor NA NA 2000000 "Cluster 20: Non-specific - DNA binding" "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA073031: AB_2732217" "unprognostic (3.83e-2)" "unprognostic (6.06e-2)" "unprognostic (6.36e-2)" "prognostic unfavorable (3.46e-6)" "unprognostic (3.46e-1)" "unprognostic (6.13e-2)" "unprognostic (1.03e-3)" "prognostic unfavorable (7.02e-4)" "unprognostic (6.65e-2)" "unprognostic (1.86e-1)" "unprognostic (1.66e-1)" "unprognostic (9.11e-2)" "unprognostic (8.88e-16)" "unprognostic (7.73e-3)" "unprognostic (5.47e-2)" "unprognostic (6.98e-2)" "unprognostic (3.00e-2)" LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 95.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 32.4;Granulosa cells: 36.9;Leydig cells: 108.7;Oocytes: 55.9;Ovarian stromal cells: 167.6;Peritubular cells: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cancer enhanced" "Detected in many" "Brain cancer: 51.0;Sarcoma: 69.5" "Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Other Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 62: Connective tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 6: Ovarian stromal cells - Transcription" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" LRRC32 "D11S833E, GARP" ENSG00000137507 "Leucine rich repeat containing 32" Q14392 11 76657524-76670747 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Growth factor binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 77.9;Endothelial cells: 147.9;Extravillous trophoblasts: 194.1;Smooth muscle cells: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.2" "Lineage enhanced" "Detected in single" "T-cells: 2.2" "Group enriched" "Detected in many" 4 "Bone cancer: 4.0;lymphoma: 11.0;Sarcoma: 8.6;testis cancer: 7.0" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055775, HPA058434" Enhanced Nucleoplasm "Intracellular and membrane" Other NA NA 98000 "Cluster 28: Neutrophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoplasm "HPA055775: AB_2732600, HPA058434: AB_2732622" "unprognostic (3.18e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (4.19e-3)" "unprognostic (1.16e-1)" "unprognostic (8.84e-2)" "unprognostic (1.39e-2)" "unprognostic (2.24e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.58e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (3.93e-5)" "unprognostic (7.99e-3)" "unprognostic (1.15e-2)" "unprognostic (5.22e-3)" "prognostic unfavorable (2.64e-4)" LTA "LT, TNFB, TNFSF1" ENSG00000226979 "Lymphotoxin alpha" P01374 6 31572054-31574324 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 1.9;lymphoid tissue: 5.5;testis: 4.1" "Cell type enhanced" "Detected in some" "B-cells: 11.3;dendritic cells: 3.4;NK-cells: 3.2;T-cells: 14.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "lymphoma: 17.1" "Adipose visceral - T-cells, Breast - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA007729 Uncertain "Secreted to blood" Cytokine NA NA 8150 "Cluster 70: Lymphoid tissue - Immune response" "Cluster 50: Lymphoma - Unknown function" "Cluster 7: T-cells - T-cell receptor" 3 "HPA007729: AB_1852906" "unprognostic (3.76e-2)" "unprognostic (1.48e-2)" "unprognostic (1.36e-3)" "unprognostic (8.99e-5)" "unprognostic (3.22e-1)" "unprognostic (5.13e-3)" "unprognostic (2.07e-1)" "unprognostic (4.71e-2)" "unprognostic (3.10e-2)" "unprognostic (3.39e-4)" "unprognostic (2.68e-2)" "unprognostic (6.77e-2)" "unprognostic (8.72e-12)" "unprognostic (2.59e-1)" "unprognostic (5.49e-2)" "unprognostic (4.30e-2)" "unprognostic (3.03e-1)" LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 155.6" "Cell type enhanced" "Detected in many" "Astrocytes: 102.8;Cardiomyocytes: 88.9;Fibroblasts: 98.2;Leydig cells: 93.8;Mucus glandular cells: 115.3;Peritubular cells: 159.3;Smooth muscle cells: 121.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 3.2" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025428 Approved "Secreted to extracellular matrix" Other NA NA 96000000 "Cluster 20: Non-specific - DNA binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" LTBP2 "C14orf141, LTBP3" ENSG00000119681 "Latent transforming growth factor beta binding protein 2" Q14767 14 74498183-74612378 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Heparin-binding" "Disease variant, Dwarfism, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 66.6;Fibroblasts: 84.3;Peritubular cells: 80.1;Salivary duct cells: 56.4;Smooth muscle cells: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Fibroblasts, Kidney - Fibroblasts" "Group enriched" "Detected in some" 10 "cerebellum: 5.3;olfactory bulb: 2.4" "Region enhanced" "Detected in all" "olfactory bulb: 20.5" HPA003415 Approved Approved Nucleoplasm "Secreted to extracellular matrix" Other NA NA 14000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA003415: AB_1079284" "unprognostic (1.24e-1)" "unprognostic (3.09e-2)" "unprognostic (5.10e-2)" "unprognostic (3.92e-3)" "unprognostic (2.08e-3)" "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (4.43e-2)" "unprognostic (1.08e-1)" "unprognostic (1.61e-1)" "unprognostic (2.80e-2)" "unprognostic (3.77e-1)" "unprognostic (1.98e-3)" "unprognostic (2.22e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.94e-4)" LTBP3 LTBP2 ENSG00000168056 "Latent transforming growth factor beta binding protein 3" Q9NS15 11 65538559-65558930 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 55.7;naive B-cell: 44.7" "Lineage enriched" "Detected in all" 5 "B-cells: 55.7" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Other NA NA 2200000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 64: Neuronal - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Fibroblasts - ECM organization" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (8.50e-3)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.24e-2)" "unprognostic (9.22e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.52e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.25e-2)" "unprognostic (2.24e-2)" LTBP4 "FLJ46318, FLJ90018, LTBP-4, LTBP-4L" ENSG00000090006 "Latent transforming growth factor beta binding protein 4" Q8N2S1 19 40592883-40629818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 284.3;Leydig cells: 956.5;Ovarian stromal cells: 322.3;Peritubular cells: 607.3;Schwann cells: 250.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015194 Approved "Secreted to extracellular matrix" Other NA NA 9700000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 24: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 2 "CAB015194: AB_2139064" "unprognostic (3.29e-2)" "unprognostic (3.91e-1)" "unprognostic (6.09e-2)" "unprognostic (9.94e-2)" "unprognostic (7.86e-3)" "unprognostic (8.41e-3)" "unprognostic (2.67e-2)" "unprognostic (5.94e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (2.36e-4)" "unprognostic (3.34e-2)" "unprognostic (4.62e-2)" "unprognostic (5.52e-3)" "unprognostic (5.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (6.83e-2)" LTF HLF2 ENSG00000012223 Lactotransferrin P02788 3 46435645-46485234 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Ion transport, Iron transport, Osteogenesis, Transcription, Transcription regulation, Transport" "Antibiotic, Antimicrobial, DNA-binding, Heparin-binding, Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 4212.2;salivary gland: 1128.6" "Group enriched" "Detected in many" 5 "Breast glandular cells: 1470.5;Club cells: 393.9;Mucus glandular cells: 1389.1;Serous glandular cells: 1532.1" "Group enriched" "Detected in all" 5 "breast cancer: 239.0;endometrial cancer: 170.3;glioma: 152.6;prostate cancer: 195.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 23 "neutrophil: 5.4;non-classical monocyte: 17.0" "Group enriched" "Detected in many" 23 "granulocytes: 5.4;monocytes: 17.0" "Cancer enhanced" "Detected in some" "Myeloma: 2.9" "Lung - Neutrophil_1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB008646, CAB016201, HPA057177, HPA059976" Enhanced "Secreted to blood" Transport NA NA 350000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 6: Bone marrow - Innate immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 17: Breast glandular cells - Lactation" "CAB008646: AB_1618695, CAB016201: AB_629860, HPA057177: AB_2683361, HPA059976: AB_2684185" "unprognostic (7.24e-3)" "unprognostic (2.43e-1)" "unprognostic (5.94e-2)" "unprognostic (3.41e-2)" "unprognostic (7.14e-3)" "unprognostic (3.45e-2)" "unprognostic (6.43e-3)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" "unprognostic (4.21e-2)" "unprognostic (3.43e-1)" "unprognostic (1.04e-1)" "prognostic favorable (6.30e-5)" "unprognostic (1.66e-2)" "unprognostic (3.53e-1)" "unprognostic (2.05e-1)" "unprognostic (9.09e-3)" LUM "LDC, SLRR2D" ENSG00000139329 Lumican P51884 12 91102629-91111494 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 714.3;placenta: 518.2" "Group enriched" "Detected in many" 5 "Endometrial stromal cells: 974.3;Fibroblasts: 1433.9;Leydig cells: 406.4;Smooth muscle cells: 502.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "choroid plexus: 8.1" "Immune cell enriched" "Detected in single" 122 "basophil: 12.1" "Lineage enriched" "Detected in single" 122 "granulocytes: 12.1" "Cancer enhanced" "Detected in many" "Rhabdoid: 228.0" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 9 "spinal cord: 197.5" "HPA001522, CAB025783" Supported "Secreted to extracellular matrix" "No annotated function" NA NA 29000000000 "Cluster 46: Basophils - Proteolysis" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 4 "CAB025783: , HPA001522: AB_1079285" "unprognostic (5.54e-2)" "unprognostic (2.27e-1)" "unprognostic (3.32e-1)" "unprognostic (2.75e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (2.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-2)" "unprognostic (2.20e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (5.25e-3)" "unprognostic (2.27e-2)" "unprognostic (2.38e-2)" "unprognostic (2.06e-2)" LUZP2 ENSG00000187398 "Leucine zipper protein 2" Q86TE4 11 24496970-25082638 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 6.3;brain: 17.2" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 1773.4" "Group enriched" "Detected in some" 7 "glioma: 3.5;prostate cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 5.7" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039007, HPA046161" Enhanced Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted in brain" "No annotated function" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039007: AB_2676307, HPA046161: AB_2679564" "unprognostic (4.49e-2)" "unprognostic (2.74e-2)" "unprognostic (8.63e-2)" "unprognostic (3.50e-1)" "unprognostic (5.22e-3)" "unprognostic (3.38e-1)" "unprognostic (4.88e-2)" "unprognostic (5.67e-4)" "unprognostic (2.40e-1)" "unprognostic (5.66e-2)" "unprognostic (6.16e-3)" "unprognostic (4.09e-2)" "unprognostic (5.18e-3)" "unprognostic (9.41e-3)" "unprognostic (4.18e-2)" "unprognostic (2.17e-1)" "unprognostic (9.64e-2)" LVRN "APQ, AQPEP, FLJ90650, TAQPEP" ENSG00000172901 Laeverin Q6Q4G3 5 115962454-116027619 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "adipose tissue: 10.6;placenta: 21.0" "Group enriched" "Detected in some" 5 "Early spermatids: 27.7;Extravillous trophoblasts: 40.5;Late spermatids: 66.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.0;Gallbladder cancer: 1.9;thyroid cancer: 1.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "spinal cord: 3.3" HPA053254 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 53: Fibroblasts - ECM organization" "HPA053254: AB_2682092" "unprognostic (1.47e-1)" "unprognostic (3.38e-3)" "unprognostic (5.81e-2)" "unprognostic (2.97e-3)" "unprognostic (5.38e-2)" "unprognostic (1.32e-1)" "unprognostic (2.59e-3)" "unprognostic (1.88e-2)" "unprognostic (2.23e-1)" "unprognostic (2.23e-2)" "unprognostic (3.83e-3)" "unprognostic (1.22e-1)" "unprognostic (1.67e-7)" "unprognostic (1.05e-2)" "unprognostic (5.94e-2)" "unprognostic (6.53e-2)" "unprognostic (3.31e-2)" LY6E "RIG-E, SCA-2, TSA-1" ENSG00000160932 "Lymphocyte antigen 6 family member E" Q16553 8 143017982-143023832 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 599.1" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 1517.6;Extravillous trophoblasts: 5448.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 756.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Other NA NA 44000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 29: Forebrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" 3 "unprognostic (1.05e-1)" "unprognostic (8.80e-2)" "unprognostic (3.88e-2)" "unprognostic (3.70e-3)" "unprognostic (9.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" "unprognostic (6.64e-2)" "unprognostic (4.94e-1)" "unprognostic (7.34e-2)" "unprognostic (1.74e-3)" "unprognostic (1.71e-2)" "prognostic unfavorable (6.74e-8)" "unprognostic (2.68e-1)" "unprognostic (2.28e-3)" "unprognostic (1.84e-3)" "unprognostic (2.12e-2)" LY6G5B "C6orf19, G5b" ENSG00000240053 "Lymphocyte antigen 6 family member G5B" Q8NDX9 6 31669976-31673776 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 3.4;Langerhans cells: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA048307 Approved "Secreted to blood" "No annotated function" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA048307: AB_2680348" "unprognostic (2.69e-2)" "unprognostic (1.52e-1)" "unprognostic (8.53e-2)" "unprognostic (1.44e-2)" "unprognostic (5.80e-2)" "unprognostic (9.85e-3)" "unprognostic (5.04e-3)" "unprognostic (8.34e-3)" "unprognostic (5.45e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-4)" "unprognostic (7.27e-3)" "unprognostic (1.98e-5)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (3.00e-2)" "unprognostic (3.98e-4)" LY6G5C "C6orf20, G5c, NG33" ENSG00000204428 "Lymphocyte antigen 6 family member G5C" Q5SRR4 6 31676684-31684040 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5" "Cell type enhanced" "Detected in many" "Early spermatids: 28.8;Spermatocytes: 16.9;Spermatogonia: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA038690 Approved "Secreted - unknown location" "No annotated function" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 50: Lymphoma - Unknown function" "Cluster 57: Platelets - Hemostasis" "HPA038690: AB_10673286" "unprognostic (1.51e-2)" "unprognostic (7.26e-2)" "unprognostic (7.19e-2)" "prognostic favorable (1.07e-4)" "unprognostic (4.83e-1)" "unprognostic (6.91e-2)" "unprognostic (1.33e-1)" "unprognostic (1.57e-2)" "unprognostic (4.27e-2)" "unprognostic (5.63e-2)" "unprognostic (3.74e-5)" "unprognostic (5.84e-2)" "unprognostic (3.78e-4)" "unprognostic (1.53e-1)" "unprognostic (2.07e-1)" "unprognostic (5.88e-2)" "unprognostic (1.39e-2)" LY6G6D "C6orf23, G6D, Ly6-D, MEGT1, NG25" ENSG00000244355 "Lymphocyte antigen 6 family member G6D" O95868 6 31715348-31717919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "seminal vesicle: 6.5;skin 1: 23.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 22 "colorectal cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "colorectal cancer: 46.5" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 6.1" "Not detected" "Not detected" HPA054412 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 13: Skin - Cornification" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 12: Squamous epithelial cells - Keratinization" 3 "HPA054412: AB_2682480" "unprognostic (5.48e-2)" "unprognostic (1.25e-1)" "unprognostic (2.81e-2)" "unprognostic (2.13e-1)" LY6H NMLY6 ENSG00000176956 "Lymphocyte antigen 6 family member H" O94772 8 143157914-143160711 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 414.1" "Cell type enhanced" "Detected in some" "Adipocytes: 22.0;Enteroendocrine cells: 18.1;Excitatory neurons: 23.9;Horizontal cells: 16.4;Inhibitory neurons: 45.7;Oligodendrocyte precursor cells: 21.2;Spermatogonia: 25.9" "Cancer enhanced" "Detected in many" "glioma: 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.6;lung cancer: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077218 Enhanced "Intracellular and membrane" "No annotated function" NA NA 12000 "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA077218: " "unprognostic (8.76e-2)" "unprognostic (2.76e-1)" "unprognostic (1.41e-2)" "unprognostic (9.45e-4)" "unprognostic (3.34e-3)" "unprognostic (1.82e-1)" "unprognostic (1.71e-4)" "unprognostic (2.26e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-3)" "unprognostic (3.76e-3)" "unprognostic (5.97e-2)" "unprognostic (2.20e-5)" "unprognostic (6.43e-3)" "unprognostic (1.54e-1)" "unprognostic (8.98e-2)" "unprognostic (9.89e-3)" LY6K "CT97, FLJ35226, HSJ001348" ENSG00000160886 "Lymphocyte antigen 6 family member K" Q17RY6 8 142700111-142705127 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.1;testis: 35.0" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 231.7;Spermatocytes: 444.7" "Cancer enhanced" "Detected in many" "cervical cancer: 11.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.7" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.7" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 742.9" "Kidney - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017770, CAB075742, CAB075743, CAB079929" Enhanced Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 21: Testis - Unknown function" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB075742: AB_2665748, CAB075743: AB_2665749, CAB079929: , HPA017770: AB_1853414" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-3)" "unprognostic (3.47e-2)" "unprognostic (2.39e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.17e-5)" "unprognostic (4.18e-2)" "unprognostic (6.89e-2)" "unprognostic (9.75e-2)" "unprognostic (1.40e-1)" "unprognostic (5.27e-5)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.61e-2)" LY86 "dJ80N2.1, MD-1" ENSG00000112799 "Lymphocyte antigen 86" O95711 6 6588108-6654983 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 76.2" "Cell type enhanced" "Detected in many" "B-cells: 152.4;Hofbauer cells: 255.0;Kupffer cells: 155.6;Langerhans cells: 122.7;Macrophages: 132.9;Microglial cells: 101.1;Schwann cells: 65.3" "Cancer enhanced" "Detected in all" "glioma: 22.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 427.5;myeloid DC: 427.0" "Group enriched" "Detected in all" 43 "B-cells: 336.4;dendritic cells: 427.0;monocytes: 427.5" "Group enriched" "Detected in some" 4 "Leukemia: 42.0;lymphoma: 44.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025000, HPA044895" Approved "Secreted to blood" Immunity NA NA 77000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 73: B-cells - B-cell function" 2 "CAB025000: , HPA044895: AB_2679138" "unprognostic (1.82e-1)" "unprognostic (2.49e-3)" "unprognostic (2.01e-2)" "unprognostic (7.88e-2)" "unprognostic (2.15e-1)" "unprognostic (1.93e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-3)" "unprognostic (3.52e-2)" "unprognostic (3.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (1.11e-1)" "unprognostic (4.20e-2)" LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 573.3;Kupffer cells: 350.9;Langerhans cells: 169.9;Macrophages: 173.3;monocytes: 121.2;Plasma cells: 141.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 632.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 632.0" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" Immunity NA NA 250000 "Cluster 28: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" 3 Vesicles "HPA053060: AB_2682029" "unprognostic (2.96e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.38e-11)" "unprognostic (2.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" LYG1 "LYGA1, SALW1939" ENSG00000144214 "Lysozyme g1" Q8N1E2 2 99284238-99304742 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 22.9" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 190.1" "Cancer enriched" "Detected in many" 15 "renal cancer: 31.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 3 "unprognostic (1.53e-2)" "unprognostic (3.13e-2)" "unprognostic (1.53e-2)" "unprognostic (3.73e-1)" "unprognostic (9.74e-2)" "unprognostic (3.76e-4)" "unprognostic (6.94e-4)" "unprognostic (2.58e-2)" "unprognostic (4.72e-2)" "unprognostic (9.74e-3)" "unprognostic (5.01e-2)" "unprognostic (1.06e-2)" "prognostic favorable (8.44e-4)" "unprognostic (1.31e-1)" "unprognostic (2.58e-1)" "unprognostic (1.07e-1)" "unprognostic (2.31e-3)" LYG2 "LYGA2, LYGH" ENSG00000185674 "Lysozyme g2" Q86SG7 2 99242246-99255666 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "retina: 3.3;skin 1: 8.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 13.3;Excitatory neurons: 18.9;Horizontal cells: 12.6;Inhibitory neurons: 16.8;Oocytes: 11.8;Rod photoreceptor cells: 27.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039179 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Skin - Cornification" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 66: Photoreceptor cells - Visual perception" 1 "HPA039179: AB_10794633" "unprognostic (5.12e-2)" "unprognostic (8.70e-3)" "unprognostic (6.29e-2)" "unprognostic (3.91e-2)" "unprognostic (1.47e-1)" "unprognostic (7.29e-2)" "unprognostic (1.86e-2)" "unprognostic (1.78e-2)" "unprognostic (1.90e-1)" "unprognostic (1.30e-2)" "unprognostic (1.30e-5)" "unprognostic (1.40e-3)" "unprognostic (1.08e-13)" "unprognostic (9.98e-2)" "unprognostic (1.44e-1)" "unprognostic (1.19e-2)" "unprognostic (9.24e-3)" LYNX1-SLURP2 ENSG00000284505 "LYNX1-SLURP2 readthrough" 8 142764334-142778224 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 6.1;intestine: 6.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.2;Serous glandular cells: 2.2;Suprabasal keratinocytes: 3.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 8 "monocytes: 1.4" "Low cancer specificity" "Detected in single" "Intracellular and membrane" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" LYPD1 "LYPDC1, MGC29643" ENSG00000150551 "LY6/PLAUR domain containing 1" Q8N2G4 2 132643286-132671579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 80.4;fallopian tube: 51.7;pituitary gland: 32.8" "Cell type enhanced" "Detected in many" "Ductal cells: 84.8;Exocrine glandular cells: 97.1;Oocytes: 101.5;Secretory cells: 306.1;Serous glandular cells: 62.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 57.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 22 "granulocytes: 3.6" "Cancer enhanced" "Detected in many" "skin cancer: 51.7" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068333 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA068333: " "unprognostic (9.25e-2)" "unprognostic (7.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.07e-2)" "unprognostic (6.40e-3)" "unprognostic (5.60e-2)" "unprognostic (8.36e-3)" "unprognostic (1.05e-2)" "unprognostic (6.70e-2)" "unprognostic (2.86e-2)" "unprognostic (1.51e-2)" "unprognostic (1.43e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" LYPD2 "LYPDC2, RGTR430, UNQ430" ENSG00000197353 "LY6/PLAUR domain containing 2" Q6UXB3 8 142750150-142752532 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "esophagus: 338.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 124.8;Club cells: 222.3;Ionocytes: 625.9;monocytes: 300.5;Serous glandular cells: 99.6" "Cancer enhanced" "Detected in many" "cervical cancer: 45.9;ovarian cancer: 46.7" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 13 "non-classical monocyte: 442.4" "Lineage enriched" "Detected in many" 22 "monocytes: 442.4" "Cancer enhanced" "Detected in some" "Bladder cancer: 10.3;head and neck cancer: 6.1;pancreatic cancer: 6.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" "No annotated function" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "prognostic favorable (2.00e-4)" "unprognostic (3.10e-2)" "prognostic favorable (2.63e-4)" "unprognostic (3.85e-3)" "unprognostic (3.75e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-2)" "unprognostic (3.11e-3)" "unprognostic (1.53e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (1.12e-1)" "unprognostic (2.04e-1)" LYPD4 MGC42718 ENSG00000273111 "LY6/PLAUR domain containing 4" Q6UWN0 19 41837074-41844697 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 306 "testis: 101.9" "Cell type enhanced" "Detected in some" "Early spermatids: 269.7;Late spermatids: 851.8;Spermatocytes: 208.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" "No annotated function" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Late spermatids - Unknown function" "unprognostic (4.07e-2)" "unprognostic (2.92e-1)" "unprognostic (3.21e-1)" "unprognostic (1.00e-1)" LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 10.7;placenta: 15.2" "Cell type enhanced" "Detected in many" "Astrocytes: 38.7;Early spermatids: 38.5;Inhibitory neurons: 63.5;Late spermatids: 242.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" "No annotated function" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 1 Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" LYPD6B "CT116, LYPD7" ENSG00000150556 "LY6/PLAUR domain containing 6B" Q8NI32 2 149038107-149215262 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 92.5" "Cell type enhanced" "Detected in many" "Early spermatids: 233.7;Gastric mucus-secreting cells: 78.4;Inhibitory neurons: 75.0;Late spermatids: 137.2;Secretory cells: 59.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "basophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049239 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 32: Basophils - Transcription" "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 21: Early spermatids - Spermatogenesis" "HPA049239: AB_2680688" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (3.12e-3)" "unprognostic (1.64e-1)" "unprognostic (3.37e-1)" "unprognostic (2.01e-2)" "unprognostic (6.27e-2)" "unprognostic (3.64e-2)" "unprognostic (7.95e-3)" "unprognostic (2.59e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-3)" LYPD8 ENSG00000259823 "LY6/PLAUR domain containing 8" Q6UX82 1 248739415-248755759 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 208.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 337.2;Intestinal goblet cells: 187.1;Paneth cells: 1045.9" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 15.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.3;lung cancer: 1.8" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" "No annotated function" NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" "unprognostic (6.69e-3)" "unprognostic (3.53e-2)" "unprognostic (1.08e-5)" "unprognostic (1.42e-2)" "unprognostic (1.35e-1)" "unprognostic (2.16e-4)" "unprognostic (8.62e-2)" "unprognostic (7.28e-2)" "unprognostic (3.22e-1)" "unprognostic (9.73e-2)" "unprognostic (1.87e-1)" "unprognostic (1.19e-4)" "unprognostic (2.57e-1)" "unprognostic (2.89e-1)" "unprognostic (1.07e-1)" LYZ ENSG00000090382 Lysozyme P61626 12 69348381-69354234 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 10445.2;salivary gland: 20501.5;stomach 1: 8699.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 3336.3;Hofbauer cells: 2606.3;Kupffer cells: 3020.6;Langerhans cells: 5810.2;Macrophages: 3871.1;Schwann cells: 1522.9;Serous glandular cells: 2909.4" "Cancer enhanced" "Detected in all" "stomach cancer: 976.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 25283.6;myeloid DC: 14448.9" "Group enriched" "Detected in all" 20 "dendritic cells: 14448.9;monocytes: 25283.6" "Cancer enhanced" "Detected in many" "Gastric cancer: 1810.2;Leukemia: 764.8" "Adipose visceral - Macrophages, Colon - Macrophages, Kidney - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000055, HPA048284, HPA066182" Enhanced Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" Enzyme NA NA 1500000000 1500000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus, Actin filaments" Nucleoplasm "CAB000055: AB_2341230, HPA048284: AB_2680339, HPA066182: AB_2732741" "unprognostic (8.52e-2)" "unprognostic (6.12e-3)" "unprognostic (2.83e-1)" "unprognostic (7.29e-2)" "unprognostic (7.91e-2)" "prognostic favorable (7.45e-4)" "unprognostic (1.21e-1)" "unprognostic (7.40e-2)" "unprognostic (1.41e-1)" "unprognostic (2.08e-2)" "unprognostic (1.44e-1)" "unprognostic (3.13e-1)" "unprognostic (2.50e-1)" "unprognostic (2.37e-1)" "unprognostic (3.65e-2)" "unprognostic (5.78e-2)" "unprognostic (3.62e-2)" LYZL1 "LYC2, MGC33408" ENSG00000120563 "Lysozyme like 1" Q6UWQ5 10 29289061-29318328 "Enzymes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 431 "testis: 49.6" "Group enriched" "Detected in some" 58 "Early spermatids: 743.4;Late spermatids: 223.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Secreted in male reproductive system" Enzyme NA NA "Cluster 10: Testis - Spermatid development" "Cluster 18: Early spermatids - Unknown function" "unprognostic (1.88e-1)" "unprognostic (8.40e-3)" LYZL2 ENSG00000151033 "Lysozyme like 2" Q7Z4W2 10 30611779-30629762 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 692 "testis: 69.1" "Group enriched" "Detected in some" 60 "Early spermatids: 872.6;Late spermatids: 276.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Secreted in male reproductive system" Enzyme NA NA "Cluster 10: Testis - Spermatid development" "Cluster 27: Breast cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" "unprognostic (2.83e-4)" LYZL4 "LYC4, MGC26768" ENSG00000157093 "Lysozyme like 4" Q96KX0 3 42397083-42410610 "Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "testis: 50.7" "Group enriched" "Detected in some" 64 "Early spermatids: 468.2;Late spermatids: 180.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA038806 Approved "Secreted in male reproductive system" Other NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 18: Early spermatids - Unknown function" "HPA038806: AB_10674841" "unprognostic (4.03e-1)" "unprognostic (5.68e-1)" "unprognostic (1.06e-1)" LYZL6 "LYC1, PRO1485, TKAL754" ENSG00000275722 "Lysozyme like 6" O75951 17 35934518-35943713 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Antimicrobial, Bacteriolytic enzyme, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "testis: 46.6" "Cell type enriched" "Detected in some" 6 "Early spermatids: 504.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025734, HPA053073" Enhanced "Secreted in male reproductive system" Enzyme NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" "HPA025734: AB_1853444, HPA053073: AB_2682034" MAGT1 "DKFZp564K142, IAP, MRX95, OST3B, SLC58A1" ENSG00000102158 "Magnesium transporter 1" Q9H0U3 X 77825747-77899271 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049851 Approved "Intracellular and membrane" Transport NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 1 "HPA049851: AB_2680913" "prognostic unfavorable (1.30e-4)" "unprognostic (3.32e-1)" "unprognostic (6.47e-2)" "unprognostic (1.16e-1)" "unprognostic (2.39e-1)" "unprognostic (3.81e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (8.98e-4)" "unprognostic (2.03e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.03e-1)" "unprognostic (1.60e-2)" "unprognostic (5.56e-3)" "unprognostic (1.14e-1)" "unprognostic (6.25e-3)" "unprognostic (1.66e-1)" MALSU1 "C7orf30, mtRsfA" ENSG00000156928 "Mitochondrial assembly of ribosomal large subunit 1" Q96EH3 7 23298739-23311729 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 258.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020487, HPA052210" Approved Enhanced Mitochondria "Intracellular and membrane" Other NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 23: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 10 Mitochondria "HPA020487: AB_1845757, HPA052210: AB_2681762" "unprognostic (3.62e-1)" "unprognostic (3.68e-1)" "unprognostic (1.43e-1)" "unprognostic (4.66e-3)" "unprognostic (5.24e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (1.08e-1)" "unprognostic (1.51e-2)" "unprognostic (9.79e-2)" "unprognostic (1.83e-3)" "unprognostic (3.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.68e-1)" MAMDC2 MGC21981 ENSG00000165072 "MAM domain containing 2" Q7Z304 9 70043848-70226972 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 72.1" "Cell type enhanced" "Detected in many" "Early spermatids: 41.7;Excitatory neurons: 35.8;Fibroblasts: 43.4;Inhibitory neurons: 41.2;Leydig cells: 94.2;Microglial cells: 43.8;Peritubular cells: 78.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 19.2" "Breast - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021814, HPA022249" Uncertain Approved "Nuclear speckles,Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 58: Macrophages - Innate immune response" 1 "Nuclear speckles, Plasma membrane" "HPA021814: AB_1853508, HPA022249: AB_2139157" "unprognostic (1.88e-1)" "unprognostic (3.16e-3)" "unprognostic (2.21e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (8.49e-2)" "unprognostic (1.27e-2)" "unprognostic (8.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.92e-1)" "unprognostic (3.67e-1)" "unprognostic (3.03e-2)" "unprognostic (4.23e-3)" "unprognostic (2.35e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (2.79e-3)" MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 26.3;dendritic cells: 39.2;Langerhans cells: 29.0;Macrophages: 27.0;Plasma cells: 57.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.7;intermediate monocyte: 178.7;myeloid DC: 159.0;non-classical monocyte: 139.1;plasmacytoid DC: 187.7" "Group enriched" "Detected in all" 5 "dendritic cells: 187.7;monocytes: 201.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 3200000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 23: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" MAN2B2 "EpMAN, KIAA0935" ENSG00000013288 "Mannosidase alpha class 2B member 2" Q9Y2E5 4 6575189-6623362 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "Secreted to blood" Enzyme NA NA 15000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 58: Macrophages - Innate immune response" 9 "unprognostic (1.30e-1)" "unprognostic (3.32e-1)" "unprognostic (1.28e-1)" "prognostic favorable (7.59e-4)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (1.31e-1)" "unprognostic (1.57e-1)" "unprognostic (5.78e-2)" "unprognostic (3.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.72e-1)" "unprognostic (6.53e-2)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-3)" "unprognostic (2.18e-1)" MANEAL FLJ31434 ENSG00000185090 "Mannosidase endo-alpha like" Q5VSG8 1 37793847-37801137 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.3;Cone photoreceptor cells: 13.6;Enteroendocrine cells: 13.7;Horizontal cells: 22.0;Inhibitory neurons: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063423 Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 47000 "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Golgi apparatus" "HPA063423: AB_2685011" "unprognostic (8.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (7.92e-2)" "prognostic favorable (5.28e-4)" "prognostic unfavorable (3.32e-4)" "unprognostic (3.02e-1)" "unprognostic (1.03e-2)" "unprognostic (7.67e-2)" "unprognostic (6.27e-3)" "unprognostic (1.08e-1)" "unprognostic (1.17e-3)" "unprognostic (8.29e-3)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (2.26e-1)" MANF "ARMET, ARP" ENSG00000145050 "Mesencephalic astrocyte derived neurotrophic factor" P55145 3 51385291-51389397 "Plasma proteins, Predicted secreted proteins" "Stress response, Unfolded protein response" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 436.0;Plasma cells: 509.3;Syncytiotrophoblasts: 511.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 109.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011175 Approved Supported "Endoplasmic reticulum" "Secreted to blood" "Growth factor" NA NA 7500000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 1 "Endoplasmic reticulum" "HPA011175: AB_1845039" "unprognostic (2.90e-2)" "unprognostic (5.24e-2)" "unprognostic (1.11e-2)" "unprognostic (2.51e-2)" "unprognostic (5.84e-2)" "prognostic unfavorable (9.58e-6)" "prognostic unfavorable (7.48e-4)" "unprognostic (7.37e-2)" "unprognostic (1.25e-1)" "unprognostic (1.12e-3)" "unprognostic (1.35e-1)" "unprognostic (3.01e-1)" "unprognostic (1.21e-2)" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (1.27e-1)" "unprognostic (5.10e-2)" MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 9.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 48.0;Inhibitory neurons: 55.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" Transcription NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 8: Neurons - Neuronal signaling" 4 "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" MAPT "DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau, tau-40" ENSG00000186868 "Microtubule associated protein tau" P10636 17 45894527-46028334 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alzheimer disease, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 135.5;skeletal muscle: 76.2" "Cell type enhanced" "Detected in many" "Astrocytes: 135.0;Bipolar cells: 278.2;Early spermatids: 130.2;Excitatory neurons: 182.9;Horizontal cells: 226.6;Inhibitory neurons: 147.3;Late spermatids: 428.0;Muller glia cells: 123.3;Oligodendrocyte precursor cells: 121.7;Oligodendrocytes: 152.5" "Cancer enhanced" "Detected in many" "breast cancer: 9.5;glioma: 13.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "Bone cancer: 46.4;Neuroblastoma: 13.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000151, HPA048895, HPA069524, HPA069570, CAB072344" Enhanced Supported "Nuclear speckles,Plasma membrane" "Secreted to blood" "No annotated function" NA NA 7100 "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" 18 "Plasma membrane" "Nuclear speckles" "CAB000151: , CAB072344: , HPA048895: AB_2680550, HPA069524: AB_2686145, HPA069570: AB_2686155" "unprognostic (1.78e-3)" "unprognostic (7.51e-2)" "unprognostic (3.71e-2)" "unprognostic (8.40e-5)" "unprognostic (1.40e-1)" "unprognostic (1.31e-2)" "unprognostic (4.06e-5)" "unprognostic (6.04e-2)" "unprognostic (2.19e-2)" "unprognostic (3.49e-2)" "unprognostic (3.88e-3)" "unprognostic (2.65e-1)" "unprognostic (1.72e-3)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (1.85e-2)" "unprognostic (5.47e-2)" MASP1 "CRARF, MAP-1, Map44, MASP, MASP-3, PRSS5" ENSG00000127241 "MBL associated serine protease 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 116.0;heart muscle: 111.9;liver: 178.0" "Cell type enhanced" "Detected in some" "Astrocytes: 26.6;Cardiomyocytes: 29.0;Cholangiocytes: 26.7;Endometrial stromal cells: 29.6;Fibroblasts: 16.5;Hepatocytes: 57.4" "Group enriched" "Detected in some" 9 "glioma: 6.8;liver cancer: 7.7;prostate cancer: 3.0;renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 11.8;Rhabdoid: 14.6" "Breast - Fibroblasts, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblast_1, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" Immunity No NA 8670000000 1900000000 "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "Nucleoplasm, Cytosol" "HPA001617: AB_1079314, HPA009641: AB_1079313" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (1.99e-1)" "unprognostic (5.20e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-6)" "prognostic favorable (2.20e-4)" "unprognostic (9.92e-2)" "unprognostic (3.22e-1)" "unprognostic (2.29e-1)" "unprognostic (4.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.82e-3)" "unprognostic (3.56e-3)" "unprognostic (1.97e-1)" "unprognostic (7.85e-2)" "unprognostic (4.29e-1)" MASP2 "MAP-2, Map19, MASP1P1, sMAP" ENSG00000009724 "MBL associated serine protease 2" O00187 1 11022009-11047239 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 57 "liver: 464.7" "Cell type enriched" "Detected in some" 47 "Hepatocytes: 634.2" "Cancer enriched" "Detected in some" 71 "liver cancer: 41.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029313, HPA029314" Uncertain Supported "Golgi apparatus" "Secreted to blood" "Complement pathway" NA NA 340000000 820000000 "Cluster 83: Liver - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 4 "Golgi apparatus" "HPA029313: AB_10669654, HPA029314: AB_10670029" "unprognostic (7.00e-2)" "unprognostic (8.37e-2)" "unprognostic (2.75e-2)" "unprognostic (2.89e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-3)" "prognostic favorable (1.60e-4)" "unprognostic (2.92e-3)" "unprognostic (3.13e-2)" "unprognostic (4.04e-2)" "unprognostic (6.90e-3)" "unprognostic (8.30e-4)" "unprognostic (7.14e-2)" "unprognostic (3.91e-1)" "unprognostic (2.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-4)" MATN1 "CMP, CRTM" ENSG00000162510 "Matrilin 1" P21941 1 30711277-30723585 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "retina: 4.8" "Cell type enhanced" "Detected in some" "B-cells: 3.0;Breast myoepithelial cells: 1.2" "Cancer enriched" "Detected in single" 4 "thyroid cancer: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA028580 Supported "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 76: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 73: B-cells - B-cell function" "HPA028580: AB_10601913" "unprognostic (4.71e-2)" "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (3.75e-6)" "unprognostic (9.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.31e-3)" "unprognostic (2.63e-1)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (7.31e-2)" "unprognostic (5.22e-2)" "unprognostic (4.01e-13)" "unprognostic (8.23e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-2)" "unprognostic (3.42e-2)" MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 113.8;Late spermatids: 106.7;Peritubular cells: 252.9;Proximal enterocytes: 109.1;Schwann cells: 270.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 1500000 "Cluster 1: T-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 2 "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" MATN3 "EDM5, HOA" ENSG00000132031 "Matrilin 3" O15232 2 19992052-20012668 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 12.8;placenta: 10.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 21.8;Breast glandular cells: 4.7;Microglial cells: 4.5;Peritubular cells: 4.8;Sertoli cells: 5.4;Smooth muscle cells: 8.0" "Cancer enhanced" "Detected in all" "pancreatic cancer: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 29.3;testis cancer: 24.9" "Lung - Alveolar cells type 1" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 2.3" "HPA051250, HPA074980" Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA 440000 "Cluster 34: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 48: Smooth muscle cells - Signal transduction" 5 "Endoplasmic reticulum, Golgi apparatus, Vesicles" "HPA051250: AB_2681406, HPA074980: " "unprognostic (3.47e-1)" "prognostic unfavorable (1.41e-4)" "unprognostic (7.57e-2)" "unprognostic (2.75e-2)" "unprognostic (1.71e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.62e-5)" "unprognostic (1.27e-1)" "unprognostic (4.84e-2)" "unprognostic (7.40e-2)" "unprognostic (3.20e-2)" "unprognostic (2.54e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.51e-1)" "unprognostic (7.04e-2)" "unprognostic (3.15e-2)" MATN4 ENSG00000124159 "Matrilin 4" O95460 20 45293445-45308529 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "pancreas: 24.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.7;Exocrine glandular cells: 2.8;Fibroblasts: 6.0;Langerhans cells: 6.0;Oligodendrocyte precursor cells: 2.8;Spermatogonia: 4.9" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" "No annotated function" NA NA 14000 "Cluster 15: Pancreas - Proteolysis" "Cluster 59: Leukemia - T-cell receptor" "Cluster 53: Fibroblasts - ECM organization" "unprognostic (1.54e-1)" "unprognostic (2.39e-2)" "unprognostic (2.22e-2)" "unprognostic (3.60e-2)" "unprognostic (8.38e-2)" "unprognostic (9.67e-2)" "unprognostic (1.84e-1)" "unprognostic (6.79e-2)" "unprognostic (6.27e-2)" "unprognostic (6.74e-3)" "unprognostic (5.53e-1)" "unprognostic (6.19e-3)" "unprognostic (3.63e-6)" "unprognostic (2.38e-1)" "unprognostic (4.69e-2)" "unprognostic (4.27e-1)" "unprognostic (5.38e-2)" MATR3 "KIAA0723, MGC9105, MPD2, VCPDM" ENSG00000015479 "Matrin 3" P43243 5 139293674-139331677 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" RNA-binding "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 63.7;Basal squamous epithelial cells: 66.7;Erythroid cells: 45.0;Plasma cells: 51.3;Squamous epithelial cells: 46.6;T-cells: 43.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033552, HPA036564, HPA036565" Supported Approved Nucleoplasm "Intracellular and membrane" Immunity NA NA 260000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 28: Neuronal - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 49: Non-specific - Transcription" 14 Nucleoplasm "CAB033552: AB_2281755, HPA036564: AB_10669907, HPA036565: AB_10673623" "unprognostic (9.33e-2)" "unprognostic (6.57e-2)" "unprognostic (8.37e-2)" "unprognostic (7.53e-2)" "unprognostic (7.20e-2)" "unprognostic (4.32e-3)" "unprognostic (1.03e-1)" "unprognostic (3.56e-2)" "unprognostic (2.96e-2)" "unprognostic (1.93e-1)" "unprognostic (1.23e-1)" "unprognostic (9.36e-2)" "unprognostic (1.08e-3)" "unprognostic (1.73e-1)" "unprognostic (1.93e-1)" "unprognostic (3.86e-2)" "unprognostic (7.90e-2)" MAU2 "KIAA0892, mau-2, MAU2L, MGC75361, SCC4" ENSG00000129933 "MAU2 sister chromatid cohesion factor" Q9Y6X3 19 19320829-19358754 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059897 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Other NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 79: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" 1 Nucleoplasm "Nuclear bodies" "HPA059897: AB_2684154" "unprognostic (3.53e-1)" "unprognostic (2.94e-2)" "unprognostic (1.18e-1)" "unprognostic (9.57e-3)" "unprognostic (1.87e-1)" "prognostic favorable (3.90e-5)" "unprognostic (1.68e-2)" "unprognostic (3.49e-3)" "unprognostic (5.56e-3)" "unprognostic (3.56e-1)" "unprognostic (3.98e-3)" "unprognostic (1.28e-1)" "unprognostic (4.27e-3)" "unprognostic (2.42e-2)" "unprognostic (1.10e-1)" "unprognostic (6.67e-3)" "unprognostic (2.96e-2)" MAZ "Pur-1, ZF87, Zif87, ZNF801" ENSG00000103495 "MYC associated zinc finger protein" P56270 16 29806106-29811164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048315, HPA059495, HPA065930" Approved Enhanced Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 51: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 1 Nucleoplasm "HPA048315: AB_2680353, HPA059495: AB_2684039, HPA065930: AB_2685579" "unprognostic (1.05e-1)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" "unprognostic (3.83e-1)" "unprognostic (3.25e-3)" "unprognostic (6.16e-2)" "unprognostic (1.27e-1)" "unprognostic (5.12e-2)" "unprognostic (2.00e-1)" "unprognostic (6.39e-3)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.20e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (7.08e-2)" MBL2 "COLEC1, MBL, MBP, MBP-C, MBP1" ENSG00000165471 "Mannose binding lectin 2" P11226 10 52765380-52772784 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement activation lectin pathway, Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2727 "liver: 272.6" "Cell type enriched" "Detected in some" 98 "Hepatocytes: 230.9" "Cancer enriched" "Detected in single" 275 "liver cancer: 22.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "liver cancer: 1.0" "Liver - Hepatocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 13 "basal ganglia: 1.3" "HPA002027, CAB016782" Enhanced "Secreted to blood" "Complement pathway" NA NA 1220000000 1900000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 9 "CAB016782: , HPA002027: AB_1079324" "unprognostic (1.72e-2)" "unprognostic (3.03e-1)" MCCC1 "MCCA, MCCCalpha" ENSG00000078070 "Methylcrotonyl-CoA carboxylase subunit 1" Q96RQ3 3 183015218-183116075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008310, HPA071630" Approved Enhanced Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 72: Alveolar cells - Lung function" 1 Mitochondria "HPA008310: AB_1853620, HPA071630: " "unprognostic (4.01e-2)" "unprognostic (1.83e-3)" "unprognostic (2.05e-2)" "unprognostic (2.59e-3)" "unprognostic (3.46e-2)" "unprognostic (4.16e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-3)" "unprognostic (2.57e-3)" "unprognostic (9.82e-2)" "unprognostic (9.74e-2)" "unprognostic (7.65e-2)" "prognostic favorable (3.68e-4)" "unprognostic (4.73e-1)" "unprognostic (2.21e-1)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" MCCD1 ENSG00000204511 "Mitochondrial coiled-coil domain 1" P59942 6 31528962-31530232 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 73 "kidney: 79.6" "Group enriched" "Detected in some" 36 "Distal tubular cells: 399.5;Proximal tubular cells: 316.3" "Group enriched" "Detected in some" 5 "breast cancer: 0.7;endometrial cancer: 0.8;liver cancer: 2.4;renal cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Intracellular and membrane" "No annotated function" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 20 "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (2.71e-1)" "unprognostic (3.22e-2)" "prognostic favorable (1.73e-4)" MCEE "GLOD2, MCE, MMCE" ENSG00000124370 "Methylmalonyl-CoA epimerase" Q96PE7 2 71109684-71130239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 110.8;Distal tubular cells: 86.1;Hepatocytes: 95.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035196 Approved Nucleoli "Intracellular and membrane" Enzyme No No 29000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Breast glandular cells - Lactation" 4 Nucleoli "HPA035196: AB_10601871" "unprognostic (7.65e-2)" "unprognostic (8.20e-2)" "unprognostic (3.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.35e-1)" "prognostic favorable (4.76e-4)" "prognostic favorable (5.78e-4)" "unprognostic (4.86e-3)" "unprognostic (6.48e-2)" "unprognostic (1.08e-1)" "unprognostic (7.43e-3)" "unprognostic (8.59e-2)" "unprognostic (9.40e-3)" "unprognostic (4.90e-2)" "unprognostic (3.55e-1)" "unprognostic (6.51e-2)" "unprognostic (5.38e-2)" MCF2L "ARHGEF14, DBS, KIAA0362, OST" ENSG00000126217 "MCF.2 cell line derived transforming sequence like" O15068 13 112894378-113099742 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 162.5" "Cell type enhanced" "Detected in many" "Adipocytes: 126.2;Bipolar cells: 61.9;Cone photoreceptor cells: 96.9;Endothelial cells: 65.6;Intestinal goblet cells: 70.9;Microglial cells: 88.6;Oligodendrocytes: 69.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 35.9" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Other NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "unprognostic (1.56e-1)" "unprognostic (2.53e-2)" "unprognostic (8.86e-3)" "prognostic favorable (6.01e-4)" "unprognostic (9.07e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.02e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.36e-5)" "unprognostic (1.17e-1)" "prognostic favorable (9.14e-6)" "unprognostic (2.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.24e-1)" "prognostic favorable (2.63e-5)" MCFD2 "F5F8D, LMAN1IP, SDNSF" ENSG00000180398 "Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit" Q8NI22 2 46901870-46941855 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Serous glandular cells: 413.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022410, HPA034593" Supported "Intracellular and membrane" Transport NA NA 1200000 "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 75: Serous glandular cells - Salivary secretion" 8 "CAB022410: , HPA034593: AB_2674239" "unprognostic (1.16e-2)" "unprognostic (5.71e-3)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (2.50e-1)" "unprognostic (2.87e-2)" "unprognostic (3.98e-2)" "unprognostic (3.10e-2)" "unprognostic (3.93e-2)" "unprognostic (8.32e-2)" "unprognostic (1.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.64e-4)" MDFIC "HIC, MDFIC1" ENSG00000135272 "MyoD family inhibitor domain containing" Q9P1T7 7 114922094-115019917 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 93.1;Muller glia cells: 104.6;T-cells: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030716 Approved Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Transcription NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Nucleoplasm, Golgi apparatus" "HPA030716: AB_10671364" "unprognostic (1.24e-3)" "unprognostic (4.15e-1)" "unprognostic (2.38e-2)" "unprognostic (2.29e-2)" "unprognostic (1.39e-1)" "unprognostic (3.13e-3)" "unprognostic (1.73e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (8.02e-2)" "unprognostic (6.38e-3)" "unprognostic (3.68e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (6.13e-3)" "unprognostic (7.10e-2)" "unprognostic (1.42e-1)" "unprognostic (3.55e-1)" MDGA1 "GPIM, MAMDC3" ENSG00000112139 "MAM domain containing glycosylphosphatidylinositol anchor 1" Q8NFP4 6 37630679-37699306 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "brain: 108.3" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Bipolar cells: 32.1;Cone photoreceptor cells: 25.5;Horizontal cells: 35.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 7 "cerebellum: 175.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031235, HPA050382" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA 1200000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Plasma membrane" "Golgi apparatus" "HPA031235: AB_10603017, HPA050382: AB_2681108" "unprognostic (4.67e-2)" "unprognostic (6.97e-3)" "unprognostic (3.24e-1)" "unprognostic (5.69e-4)" "unprognostic (2.75e-2)" "unprognostic (2.41e-1)" "unprognostic (1.45e-2)" "unprognostic (2.00e-1)" "unprognostic (2.02e-2)" "unprognostic (1.45e-1)" "unprognostic (2.16e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-5)" "unprognostic (9.19e-3)" "unprognostic (5.28e-3)" "unprognostic (3.80e-3)" "unprognostic (4.60e-2)" MDK "FLJ27379, MK, NEGF2" ENSG00000110492 Midkine P21741 11 46380756-46383837 "Cancer-related genes, Predicted secreted proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 588.2" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 656.5;Granulosa cells: 739.5;Ovarian stromal cells: 1036.0;Paneth cells: 1087.7;Proximal enterocytes: 793.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.8;neutrophil: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010055, HPA057126" Uncertain Approved Vesicles "Secreted to blood" "Growth factor" NA NA 158000 960000 "Cluster 62: Connective tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 9 Vesicles "CAB010055: AB_627949, HPA057126: AB_2683344" "unprognostic (8.87e-3)" "unprognostic (6.65e-2)" "unprognostic (4.02e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.90e-1)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.11e-2)" "unprognostic (4.01e-2)" "unprognostic (4.15e-1)" "prognostic unfavorable (3.06e-6)" "unprognostic (8.78e-2)" "unprognostic (1.31e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" MEGF10 "KIAA1780, SR-F3" ENSG00000145794 "Multiple EGF like domains 10" Q96KG7 5 127290796-127465737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis, Phagocytosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.9;retina: 7.8" "Group enriched" "Detected in some" 4 "Astrocytes: 207.1;Oligodendrocyte precursor cells: 91.5;Oligodendrocytes: 355.2" "Cancer enhanced" "Detected in some" "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Sarcoma: 10.0;skin cancer: 6.9" "Colon - Enteric glia cells, Liver - Hepatocytes, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011401 Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 73000000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 47: Astrocytes - Unknown function" "Plasma membrane" "HPA011401: " "unprognostic (7.02e-2)" "unprognostic (4.50e-2)" "unprognostic (1.02e-1)" "unprognostic (2.26e-3)" "unprognostic (8.91e-3)" "unprognostic (1.59e-2)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.52e-1)" "unprognostic (1.41e-1)" "unprognostic (1.76e-4)" "unprognostic (5.28e-3)" "unprognostic (2.59e-1)" "unprognostic (9.36e-4)" "unprognostic (1.17e-1)" MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 24.4;Lymphatic endothelial cells: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Prostate basal glandular cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" "No annotated function" Yes No 1700000 "Cluster 22: Eosinophils - Transcription" "Cluster 13: Skin - Cornification" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 3 Microtubules "Cytokinetic bridge" "HPA052129: AB_2681739" "unprognostic (1.95e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.16e-2)" "unprognostic (2.38e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.19e-1)" "unprognostic (4.16e-2)" "unprognostic (1.73e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-3)" "unprognostic (1.60e-1)" "unprognostic (1.64e-1)" "unprognostic (9.51e-2)" "unprognostic (3.43e-2)" MEI1 "MGC40042, SPATA38" ENSG00000167077 "Meiotic double-stranded break formation protein 1" Q5TIA1 22 41699503-41799456 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.9;testis: 38.4" "Cell type enhanced" "Detected in many" "Early spermatids: 62.4;Late spermatids: 53.9;NK-cells: 25.8;Plasma cells: 119.9;Spermatocytes: 43.2;T-cells: 25.2" "Cancer enhanced" "Detected in many" "cervical cancer: 5.5" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Myeloma: 13.7" "Breast - Plasma cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 4 "olfactory bulb: 2.3" HPA049240 Approved "Intracellular and membrane" Other NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "HPA049240: AB_2680689" "unprognostic (1.95e-3)" "prognostic favorable (1.59e-6)" "unprognostic (6.13e-3)" "unprognostic (1.86e-2)" "unprognostic (9.70e-2)" "unprognostic (2.97e-3)" "unprognostic (9.04e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" "unprognostic (5.96e-2)" "unprognostic (9.65e-2)" "unprognostic (2.62e-1)" "unprognostic (2.45e-10)" "unprognostic (2.82e-1)" "unprognostic (3.02e-1)" "unprognostic (1.85e-1)" "unprognostic (7.39e-2)" MELTF "CD228, FLJ38863, MAP97, MFI2, MGC4856, MTf, MTF1" ENSG00000163975 Melanotransferrin P08582 3 196980590-197029835 "CD markers, Plasma proteins, Predicted intracellular proteins" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 34.1;salivary gland: 69.2" "Cell type enhanced" "Detected in many" "Ductal cells: 28.1;granulocytes: 43.4;Mesothelial cells: 33.3;Serous glandular cells: 27.2" "Cancer enhanced" "Detected in all" "melanoma: 32.7" "Region enhanced" "Detected in all" "choroid plexus: 63.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 190.5" "Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA004880 Approved "Intracellular and membrane" Transport NA NA 41000000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Non-specific - Mixed function" 1 "HPA004880: AB_1853844" "unprognostic (8.68e-3)" "unprognostic (3.68e-2)" "unprognostic (1.75e-2)" "unprognostic (7.68e-3)" "unprognostic (1.06e-2)" "unprognostic (1.08e-2)" "unprognostic (5.53e-2)" "unprognostic (1.64e-3)" "unprognostic (1.20e-2)" "unprognostic (1.23e-1)" "unprognostic (3.68e-3)" "unprognostic (8.14e-2)" "prognostic unfavorable (6.99e-11)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "unprognostic (5.75e-2)" "unprognostic (2.09e-2)" MEP1B ENSG00000141434 "Meprin A subunit beta" Q16820 18 32185069-32220404 "Enzymes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "intestine: 353.8" "Cell type enriched" "Detected in some" 50 "Proximal enterocytes: 199.6" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "colorectal cancer: 3.1;Myeloma: 2.3" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029119 Enhanced "Secreted to digestive system" Enzyme NA NA 310000 "Cluster 25: Small intestine - Absorption" "Cluster 9: Non-specific - Receptor signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "HPA029119: AB_2672913" "unprognostic (1.33e-1)" "unprognostic (6.72e-2)" "unprognostic (2.79e-2)" "unprognostic (1.00e-1)" "unprognostic (3.50e-4)" "unprognostic (1.27e-1)" "unprognostic (1.74e-2)" "unprognostic (4.30e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (8.31e-4)" "unprognostic (4.74e-2)" "unprognostic (3.39e-1)" "unprognostic (2.71e-1)" "unprognostic (3.39e-2)" "unprognostic (3.75e-2)" MEPE ENSG00000152595 "Matrix extracellular phosphoglycoprotein" Q9NQ76 4 87821398-87846814 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 46 "brain: 4.6" "Cell type enriched" "Detected in single" 18 "Inhibitory neurons: 12.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 15.8;cerebral cortex: 55.6;hypothalamus: 17.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "amygdala: 1.0" "HPA038003, HPA038004" Uncertain "Secreted to extracellular matrix" Other NA NA 810000 "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA038003: AB_2675780, HPA038004: AB_10670537" "unprognostic (2.88e-1)" "unprognostic (8.15e-2)" "unprognostic (3.62e-1)" "unprognostic (1.91e-1)" "unprognostic (1.61e-1)" "unprognostic (4.76e-2)" "unprognostic (1.11e-1)" "unprognostic (3.14e-2)" "unprognostic (1.98e-1)" "unprognostic (2.41e-1)" "unprognostic (5.64e-4)" MESD "BOCA, KIAA0081, MESDC2" ENSG00000117899 "Mesoderm development LRP chaperone" Q14696 15 80946289-80989828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" Chaperone "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 356.7;Syncytiotrophoblasts: 475.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039414, HPA041721" Approved Supported "Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Other NA NA 1600000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 53: Non-specific - Glycosylation" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 24: Cytotrophoblasts - Mitochondria" 51 "Endoplasmic reticulum" "Nuclear bodies, Cytosol" "HPA039414: AB_10674981, HPA041721: AB_2756310" "unprognostic (9.21e-2)" "unprognostic (4.50e-2)" "unprognostic (8.02e-2)" "prognostic favorable (2.31e-4)" "unprognostic (4.93e-3)" "unprognostic (2.32e-3)" "unprognostic (3.47e-2)" "unprognostic (3.09e-3)" "unprognostic (4.04e-1)" "prognostic favorable (1.12e-4)" "unprognostic (7.93e-2)" "unprognostic (3.05e-2)" "unprognostic (3.42e-2)" "unprognostic (1.68e-1)" "unprognostic (4.32e-2)" "unprognostic (3.83e-1)" "unprognostic (1.88e-1)" MEST PEG1 ENSG00000106484 "Mesoderm specific transcript" Q5EB52 7 130486171-130506465 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 745.6" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 831.0;Syncytiotrophoblasts: 815.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 24.2" "Group enriched" "Detected in all" 4 "dendritic cells: 9.2;granulocytes: 19.4;T-cells: 24.2" "Cancer enhanced" "Detected in all" "Rhabdoid: 745.8;Uterine cancer: 608.1" "Breast - Adipocytes (Breast), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005623 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 58: Placenta - Pregnancy" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 6 "Golgi apparatus, Cytosol" "HPA005623: AB_1079364" "unprognostic (6.14e-2)" "unprognostic (5.06e-3)" "unprognostic (9.82e-2)" "unprognostic (1.64e-3)" "unprognostic (3.02e-1)" "unprognostic (1.88e-1)" "unprognostic (9.36e-3)" "unprognostic (1.12e-1)" "unprognostic (7.81e-2)" "unprognostic (6.22e-2)" "unprognostic (1.16e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (6.20e-5)" "unprognostic (7.09e-2)" "unprognostic (1.05e-1)" "unprognostic (2.30e-1)" "unprognostic (1.67e-2)" MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 41.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 95.5;Cytotrophoblasts: 75.8;Glandular and luminal cells: 138.4;Mesothelial cells: 72.0;Salivary duct cells: 113.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 289.3" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" Receptor NA NA 179000000 100000000 "Cluster 11: Liver - Plasma proteins" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 16 "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" METRN "C16orf23, MGC2601" ENSG00000103260 "Meteorin, glial cell differentiation regulator" Q9UJH8 16 715118-719655 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 390.3;choroid plexus: 179.5" "Cell type enriched" "Detected in many" 4 "Muller glia cells: 1025.4" "Cancer enhanced" "Detected in all" "glioma: 69.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Region enhanced" "Detected in all" "cerebellum: 612.7" "Low region specificity" "Detected in some" HPA051164 Approved Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted in brain" "Developmental protein" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 10: Muller glia cells - Visual perception" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA051164: AB_2681369" "unprognostic (1.60e-2)" "unprognostic (3.49e-1)" "unprognostic (4.47e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (7.49e-2)" "unprognostic (1.82e-1)" "unprognostic (2.59e-1)" "unprognostic (8.13e-2)" "unprognostic (2.35e-1)" "unprognostic (2.12e-2)" "unprognostic (3.32e-1)" "unprognostic (5.03e-3)" "unprognostic (3.62e-2)" "unprognostic (1.26e-1)" "unprognostic (3.09e-1)" "unprognostic (2.17e-2)" METRNL ENSG00000176845 "Meteorin like, glial cell differentiation regulator" Q641Q3 17 83079609-83095122 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 244.8" "Cell type enhanced" "Detected in many" "dendritic cells: 344.0;granulocytes: 367.7;monocytes: 1274.4;NK-cells: 739.5;Schwann cells: 299.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023792 Uncertain "Secreted to blood" Hormone NA NA 445000 1300000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA023792: AB_2144182" "unprognostic (7.99e-2)" "unprognostic (2.32e-1)" "unprognostic (1.04e-1)" "unprognostic (1.32e-2)" "unprognostic (6.41e-3)" "unprognostic (7.35e-2)" "unprognostic (4.26e-2)" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (1.01e-1)" "unprognostic (8.51e-2)" "unprognostic (3.50e-3)" "unprognostic (4.43e-1)" "unprognostic (2.23e-1)" "unprognostic (2.46e-1)" "unprognostic (1.61e-2)" METTL17 "FLJ20859, METT11D1" ENSG00000165792 "Methyltransferase like 17" Q9H7H0 14 20989973-20997035 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002955, HPA059802" Uncertain Enhanced Nucleoplasm "Intracellular and membrane" Enzyme No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 49: Non-specific - Transcription" 11 Nucleoplasm "HPA002955: AB_2144183, HPA059802: AB_2684129" "unprognostic (1.90e-2)" "unprognostic (1.21e-1)" "unprognostic (2.17e-1)" "unprognostic (2.53e-1)" "unprognostic (2.88e-1)" "unprognostic (1.28e-1)" "unprognostic (1.00e-2)" "unprognostic (2.23e-3)" "unprognostic (1.90e-1)" "unprognostic (1.33e-1)" "unprognostic (1.39e-1)" "unprognostic (4.02e-2)" "unprognostic (3.06e-2)" "unprognostic (1.39e-2)" "unprognostic (1.35e-1)" "unprognostic (2.11e-1)" "unprognostic (3.29e-2)" METTL24 "C6orf186, dJ71D21.2" ENSG00000053328 "Methyltransferase like 24" Q5JXM2 6 110243940-110358349 "Predicted secreted proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "smooth muscle: 11.3" "Group enriched" "Detected in some" 4 "Astrocytes: 28.5;Excitatory neurons: 23.0;Inhibitory neurons: 27.5;Late spermatids: 8.1;Oligodendrocyte precursor cells: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 2.4" "Lineage enriched" "Detected in single" 11 "T-cells: 2.4" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Liver - Hepatic stellate cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA037441, HPA037442" Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" "HPA037441: AB_10670933, HPA037442: AB_10696931" "unprognostic (6.62e-2)" "unprognostic (1.15e-1)" "unprognostic (9.31e-3)" "unprognostic (5.02e-2)" "unprognostic (5.21e-3)" "unprognostic (1.46e-1)" "unprognostic (6.12e-2)" "unprognostic (2.06e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (8.45e-2)" "unprognostic (5.96e-2)" "unprognostic (1.54e-4)" "unprognostic (4.08e-2)" "unprognostic (1.23e-2)" "unprognostic (1.63e-2)" "unprognostic (4.78e-3)" METTL9 DREV1 ENSG00000197006 "Methyltransferase like 9" Q9H1A3 16 21597218-21657471 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 329.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053588, HPA056347" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 40: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "Nucleoplasm, Cell Junctions" Cytosol "HPA053588: AB_2682203, HPA056347: " "unprognostic (1.55e-1)" "unprognostic (2.18e-2)" "unprognostic (1.98e-3)" "unprognostic (5.43e-2)" "unprognostic (5.81e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (8.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.11e-2)" "unprognostic (7.57e-3)" "unprognostic (1.73e-2)" "unprognostic (3.18e-1)" "unprognostic (1.49e-3)" "unprognostic (2.14e-1)" "unprognostic (3.28e-1)" "unprognostic (5.17e-2)" "unprognostic (1.65e-1)" MEX3C "FLJ38871, RKHD2, RNF194" ENSG00000176624 "Mex-3 RNA binding family member C" Q5U5Q3 18 51174550-51218333 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 114.8" "Group enriched" "Detected in all" 7 "Early spermatids: 457.7;Late spermatids: 571.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040603 Uncertain Approved Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 32: Basophils - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 11: Late spermatids - Unknown function" 1 Vesicles "HPA040603: AB_10805714" "unprognostic (1.09e-1)" "unprognostic (2.90e-2)" "unprognostic (8.88e-2)" "unprognostic (8.88e-3)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "prognostic unfavorable (8.49e-5)" "unprognostic (4.34e-2)" "unprognostic (4.43e-1)" "unprognostic (1.05e-2)" "unprognostic (1.03e-2)" "unprognostic (6.75e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-1)" "unprognostic (8.01e-2)" "unprognostic (3.17e-1)" MFAP2 "MAGP, MAGP-1" ENSG00000117122 "Microfibril associated protein 2" P55001 1 16974502-16980632 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 237.3;Fibroblasts: 62.4;Granulosa cells: 75.3;Leydig cells: 54.3;Lymphatic endothelial cells: 62.2;Peritubular cells: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA007354 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 210000 "Cluster 62: Connective tissue - ECM organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "HPA007354: AB_1079365" "unprognostic (5.10e-2)" "unprognostic (3.81e-2)" "unprognostic (2.62e-1)" "unprognostic (2.92e-2)" "unprognostic (4.86e-1)" "unprognostic (1.53e-3)" "unprognostic (3.72e-3)" "unprognostic (2.21e-1)" "unprognostic (1.85e-2)" "unprognostic (1.98e-1)" "unprognostic (9.45e-3)" "unprognostic (9.12e-2)" "prognostic unfavorable (2.52e-8)" "unprognostic (2.18e-3)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (5.66e-3)" MFAP3L "KIAA0626, NYD-sp9" ENSG00000198948 "Microfibril associated protein 3 like" O75121 4 169986597-170033031 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 45.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1849.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 5.7;eosinophil: 1.8;neutrophil: 3.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.7" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017986, HPA062306, HPA077490" Enhanced Supported "Nucleoplasm,Cell Junctions" "Intracellular and membrane" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Testis - Spermatid development" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoplasm "Cell Junctions" "HPA017986: AB_1853842, HPA062306: , HPA077490: AB_2686842" "unprognostic (8.04e-3)" "unprognostic (8.67e-3)" "unprognostic (3.74e-1)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (7.92e-2)" "unprognostic (3.50e-2)" "unprognostic (3.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.33e-1)" "unprognostic (3.96e-1)" "unprognostic (7.58e-2)" "prognostic favorable (1.42e-8)" "unprognostic (6.59e-3)" "unprognostic (2.12e-1)" "unprognostic (1.62e-4)" "unprognostic (2.40e-3)" MFAP4 ENSG00000166482 "Microfibril associated protein 4" P55083 17 19383442-19387190 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 607.9;Lymphatic endothelial cells: 90.9;Ovarian stromal cells: 144.0;Peritubular cells: 227.4;Smooth muscle cells: 193.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "eosinophil: 1.0;intermediate monocyte: 1.8;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 15 "granulocytes: 1.0;monocytes: 1.9" "Cancer enhanced" "Detected in many" "Bone cancer: 118.8;Neuroblastoma: 110.6" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054097 Supported Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "Cell adhesion" NA NA 110000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Endoplasmic reticulum" "HPA054097: AB_2682378" "unprognostic (3.02e-2)" "unprognostic (9.07e-2)" "unprognostic (3.39e-1)" "unprognostic (8.56e-3)" "unprognostic (9.80e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.37e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.83e-7)" "unprognostic (1.07e-2)" "unprognostic (2.92e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (7.12e-4)" MFAP5 "MAGP2, MP25" ENSG00000197614 "Microfibril associated protein 5" Q13361 12 8637346-8662888 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 234.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 146.4;Extravillous trophoblasts: 1252.1;Fibroblasts: 684.6;Syncytiotrophoblasts: 282.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "testis cancer: 126.5" "Lung - Fibroblast_2, Pancreas - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 10 "spinal cord: 56.8" HPA010553 Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 3200000 "Cluster 35: Neutrophils - Protein binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 2: Neurons - Nucleosome" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA010553: AB_1853843" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (4.25e-2)" "unprognostic (4.84e-2)" "unprognostic (1.44e-1)" "unprognostic (6.05e-2)" "unprognostic (2.15e-3)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (8.79e-2)" "unprognostic (8.63e-3)" "unprognostic (3.05e-1)" "unprognostic (4.41e-7)" "prognostic unfavorable (6.87e-4)" "unprognostic (8.81e-2)" "unprognostic (2.05e-2)" "prognostic unfavorable (5.81e-4)" MFGE8 "BA46, EDIL1, hP47, HsT19888, MFG-E8, OAcGD3S, SED1, SPAG10" ENSG00000140545 "Milk fat globule EGF and factor V/VIII domain containing" Q08431 15 88898683-88913468 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 402.7;Rod photoreceptor cells: 943.1;Sertoli cells: 473.2;Smooth muscle cells: 549.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 15.9" "Group enriched" "Detected in many" 7 "granulocytes: 5.7;NK-cells: 7.7;T-cells: 15.9" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002753, HPA002807" Enhanced Approved Cytosol "Secreted to blood" "Cell adhesion" NA NA 2830000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" Cytosol "CAB002753: , HPA002807: AB_1078072" "unprognostic (1.28e-1)" "unprognostic (1.23e-1)" "unprognostic (1.63e-2)" "unprognostic (7.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.11e-3)" "unprognostic (6.27e-2)" "unprognostic (8.49e-2)" "unprognostic (3.99e-1)" "prognostic unfavorable (6.06e-9)" "prognostic unfavorable (3.08e-4)" "unprognostic (4.85e-2)" "unprognostic (7.36e-3)" "unprognostic (2.41e-3)" MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486393 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "Adipocytes: 49.5;B-cells: 33.0;Endothelial cells: 40.4;Erythroid cells: 40.1;Hofbauer cells: 38.6;Kupffer cells: 39.9;monocytes: 40.5;NK-cells: 57.2;Plasma cells: 34.7;T-cells: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 149.5;lymphoma: 165.2;Myeloma: 119.2" "Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" "Developmental protein" NA NA 74000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" Vesicles "HPA048936: AB_2680564, HPA056479: " "unprognostic (1.21e-1)" "unprognostic (4.17e-3)" "prognostic unfavorable (5.12e-4)" "prognostic favorable (1.65e-4)" "unprognostic (6.41e-3)" "unprognostic (1.00e-2)" "unprognostic (2.64e-1)" "unprognostic (2.36e-2)" "unprognostic (4.64e-2)" "unprognostic (2.91e-2)" "unprognostic (5.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (2.67e-1)" "unprognostic (4.03e-2)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" MFSD4B "KIAA1919, MGC33953, SLC60A2" ENSG00000173214 "Major facilitator superfamily domain containing 4B" Q5TF39 6 111259327-111445354 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 82.0;Rod photoreceptor cells: 80.1;Syncytiotrophoblasts: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031784 Approved "Intracellular and membrane" Transport NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 55: Non-specific - Transcription" 2 "HPA031784: AB_10603775" "unprognostic (2.98e-2)" "unprognostic (1.64e-2)" "unprognostic (1.89e-2)" "unprognostic (3.00e-1)" "unprognostic (1.94e-1)" "unprognostic (3.07e-2)" "unprognostic (7.50e-5)" "unprognostic (3.51e-2)" "unprognostic (2.33e-1)" "unprognostic (6.84e-2)" "unprognostic (2.94e-2)" "unprognostic (3.41e-1)" "unprognostic (6.04e-3)" "unprognostic (9.27e-2)" "unprognostic (3.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.98e-4)" MGAT3 GNT-III ENSG00000128268 "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase" Q09327 22 39457012-39492194 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.2;intestine: 27.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 28.3;Excitatory neurons: 24.3;Horizontal cells: 27.7;Inhibitory neurons: 26.2;Late spermatids: 26.4;Oligodendrocyte precursor cells: 20.3;Oligodendrocytes: 42.5;Proximal enterocytes: 32.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4;eosinophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Myeloma: 58.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017598 Approved "Intracellular and membrane" Enzyme NA NA 170000 "Cluster 22: Eosinophils - Transcription" "Cluster 65: Cerebellum - Nervous system development" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA017598: AB_1853853" "unprognostic (1.41e-3)" "unprognostic (5.98e-3)" "unprognostic (4.79e-2)" "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (5.71e-3)" "unprognostic (8.92e-2)" "unprognostic (2.17e-1)" "unprognostic (4.35e-3)" "unprognostic (6.77e-2)" "unprognostic (8.12e-3)" "unprognostic (8.74e-2)" "prognostic unfavorable (5.04e-8)" "unprognostic (6.73e-2)" "unprognostic (1.46e-1)" "unprognostic (5.89e-2)" "unprognostic (4.92e-2)" MGAT4A "GnT-4a, GnT-Iva" ENSG00000071073 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A" Q9UM21 2 98619106-98731132 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 94.8" "Cell type enhanced" "Detected in all" "Microglial cells: 167.3;NK-cells: 141.3;Proximal enterocytes: 129.1;T-cells: 116.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007608 Enhanced Approved "Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 11: T-cells - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Golgi apparatus" "HPA007608: AB_10602008" "prognostic unfavorable (4.30e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.48e-8)" "unprognostic (1.35e-1)" "unprognostic (2.28e-2)" "unprognostic (3.82e-3)" "unprognostic (1.89e-1)" "unprognostic (3.76e-1)" "unprognostic (3.58e-1)" "unprognostic (2.80e-2)" "unprognostic (2.32e-2)" "unprognostic (4.17e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.04e-2)" "unprognostic (2.04e-1)" MGAT4B GnT-Ivb ENSG00000161013 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B" Q9UQ53 5 179797597-179806952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 270.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 209.2;Proximal enterocytes: 212.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 5.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.5" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012804, HPA052134" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA 19000 "Cluster 19: Eosinophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 2 Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA012804: , HPA052134: AB_2681741" "unprognostic (2.01e-2)" "unprognostic (8.68e-3)" "unprognostic (1.40e-1)" "unprognostic (3.83e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (3.61e-3)" "unprognostic (7.57e-3)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (5.13e-2)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "prognostic favorable (5.78e-4)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.42e-1)" MGAT5 "GNT-V, MGAT5A" ENSG00000152127 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase" Q09328 2 134119983-134454621 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.7;Inhibitory neurons: 129.3;Microglial cells: 135.1;Oligodendrocyte precursor cells: 117.0;Oligodendrocytes: 461.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010919 Approved "Intracellular and membrane" Enzyme NA NA 440000 "Cluster 22: Eosinophils - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 51: Oligodendrocytes - Unknown function" "HPA010919: AB_10601864" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.21e-2)" "unprognostic (3.65e-1)" "unprognostic (3.76e-1)" "unprognostic (4.45e-3)" "unprognostic (3.41e-3)" "unprognostic (5.68e-2)" "unprognostic (8.63e-3)" "unprognostic (1.59e-1)" "unprognostic (2.64e-1)" "unprognostic (5.97e-2)" "unprognostic (1.81e-2)" "unprognostic (9.27e-2)" "unprognostic (2.17e-2)" "unprognostic (1.91e-1)" MGP ENSG00000111341 "Matrix Gla protein" P08493 12 14880864-14885857 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 8976.4;Breast myoepithelial cells: 5372.2;Fibroblasts: 4620.8;Leydig cells: 2014.3;Serous glandular cells: 4800.3;Smooth muscle cells: 2428.7" "Cancer enriched" "Detected in all" 5 "breast cancer: 845.3" "Region enriched" "Detected in all" 6 "choroid plexus: 329.6" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.6" "Group enriched" "Detected in many" 4 "breast cancer: 636.8;Rhabdoid: 1570.8" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013949 Approved "Secreted to blood" "Developmental protein" NA NA 29000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA013949: AB_1853599" "unprognostic (5.71e-3)" "unprognostic (5.85e-3)" "unprognostic (1.20e-3)" "unprognostic (2.83e-2)" "unprognostic (1.27e-1)" "unprognostic (1.21e-1)" "unprognostic (1.55e-2)" "unprognostic (4.17e-3)" "unprognostic (1.01e-2)" "unprognostic (6.93e-2)" "unprognostic (1.90e-1)" "unprognostic (4.26e-2)" "prognostic unfavorable (4.15e-6)" "unprognostic (1.55e-2)" "unprognostic (4.69e-2)" "unprognostic (7.50e-2)" "unprognostic (8.97e-3)" MIA CD-RAP ENSG00000261857 "MIA SH3 domain containing" Q16674 19 40771648-40777490 "Cancer-related genes, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 56.0;pituitary gland: 74.2;salivary gland: 41.9;stomach 1: 64.0" "Group enriched" "Detected in some" 6 "Breast glandular cells: 43.9;Breast myoepithelial cells: 91.8;Melanocytes: 147.7;Schwann cells: 74.1" "Cancer enriched" "Detected in many" 5 "melanoma: 58.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Cancer enriched" "Detected in many" 5 "skin cancer: 473.9" "Colon - Enteric glia cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 27 "olfactory bulb: 25.9" HPA042369 Approved "Secreted to blood" "Growth factor" NA NA 8270000 64000 "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Stomach - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Non-specific - Mixed function" "HPA042369: AB_10794420" "prognostic favorable (2.08e-4)" "unprognostic (1.30e-1)" "unprognostic (3.15e-1)" "unprognostic (9.02e-3)" "unprognostic (2.27e-1)" "unprognostic (1.11e-1)" "unprognostic (6.37e-3)" "unprognostic (3.67e-2)" "unprognostic (1.61e-1)" "unprognostic (9.37e-2)" "unprognostic (1.17e-1)" "unprognostic (3.19e-1)" "unprognostic (3.29e-8)" "unprognostic (5.88e-2)" "unprognostic (2.44e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" MIA2 "cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, CTAGE5, FLJ22404, MEA6, MGEA, MGEA11, MGEA6, TALI" ENSG00000150527 "MIA SH3 domain ER export factor 2" Q96PC5 14 39230231-39388513 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 131.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "choroid plexus: 135.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000387, HPA000922, HPA054066, HPA055459" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 75: Serous glandular cells - Salivary secretion" 7 "Endoplasmic reticulum" "HPA000387: AB_1078582, HPA000922: AB_1078581, HPA054066: AB_2682368, HPA055459: AB_2682819" "unprognostic (2.62e-1)" "unprognostic (7.17e-3)" "unprognostic (2.33e-1)" "unprognostic (5.27e-4)" "unprognostic (3.21e-4)" "unprognostic (2.63e-1)" "unprognostic (2.48e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.93e-2)" "unprognostic (8.08e-2)" "unprognostic (2.91e-1)" "unprognostic (3.97e-2)" MICOS13 "C19orf70, MIC12, MIC13, P117, QIL1" ENSG00000174917 "Mitochondrial contact site and cristae organizing system subunit 13" Q5XKP0 19 5678421-5680516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Late spermatids: 3896.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042672 Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 7 Mitochondria Nucleoplasm "HPA042672: AB_10794531" "unprognostic (9.54e-2)" "unprognostic (4.90e-3)" "unprognostic (3.04e-1)" "unprognostic (3.21e-3)" "unprognostic (1.52e-2)" "unprognostic (1.80e-1)" "unprognostic (1.65e-1)" "unprognostic (2.53e-3)" "unprognostic (2.14e-2)" "unprognostic (9.32e-2)" "unprognostic (2.50e-2)" "unprognostic (1.57e-1)" "prognostic favorable (7.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.94e-2)" "unprognostic (2.27e-1)" "unprognostic (5.47e-2)" MIER1 "hMI-ER1, KIAA1610, MI-ER1" ENSG00000198160 "MIER1 transcriptional regulator" Q8N108 1 66924895-66988619 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019589, HPA050306" Enhanced Enhanced Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 6: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 Nucleoplasm "HPA019589: AB_1853953, HPA050306: AB_2681080" "unprognostic (3.38e-3)" "unprognostic (1.34e-1)" "prognostic favorable (4.96e-4)" "unprognostic (1.63e-1)" "prognostic favorable (3.44e-8)" "unprognostic (1.61e-1)" "unprognostic (3.15e-3)" "unprognostic (1.32e-1)" "unprognostic (1.05e-1)" "unprognostic (3.92e-3)" "unprognostic (4.48e-3)" "unprognostic (2.57e-2)" "unprognostic (2.81e-2)" "unprognostic (2.25e-2)" "unprognostic (2.73e-1)" "unprognostic (5.15e-2)" "unprognostic (2.45e-2)" MIF "GIF, GLIF" ENSG00000240972 "Macrophage migration inhibitory factor" P14174 22 23894383-23895227 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Isomerase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2046.9;Mesothelial cells: 1648.6;Proximal tubular cells: 2208.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003868, CAB005284" Approved Enhanced Nucleoplasm,Cytosol "Secreted to blood" Cytokine No No 13800000 5000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 4 Cytosol Nucleoplasm "CAB005284: AB_648587, HPA003868: AB_1079290" "unprognostic (1.68e-1)" "unprognostic (7.79e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.36e-2)" "unprognostic (9.48e-2)" "unprognostic (1.22e-3)" "unprognostic (2.17e-2)" "unprognostic (1.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.28e-2)" "unprognostic (2.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" MINPP1 MIPP ENSG00000107789 "Multiple inositol-polyphosphate phosphatase 1" Q9UNW1 10 87504875-87553461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Erythroid cells: 192.7;Hepatocytes: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026859 Approved "Intracellular and membrane" Enzyme NA NA 370000000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 40: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 1 "HPA026859: AB_1853961" "unprognostic (9.15e-2)" "unprognostic (8.76e-3)" "unprognostic (2.08e-2)" "unprognostic (2.97e-1)" "unprognostic (1.35e-1)" "unprognostic (5.20e-3)" "unprognostic (3.47e-2)" "unprognostic (1.74e-1)" "unprognostic (4.55e-1)" "unprognostic (2.07e-2)" "unprognostic (6.54e-2)" "unprognostic (6.50e-3)" "prognostic unfavorable (6.98e-5)" "unprognostic (2.43e-1)" "unprognostic (2.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.01e-2)" MLN ENSG00000096395 Motilin P12872 6 33794673-33804003 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 411 "intestine: 247.0" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "testis cancer: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "HPA069392, HPA077622" Enhanced "Secreted to blood" Hormone NA NA 450000 200000 "Cluster 25: Small intestine - Absorption" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 9: Endometrial stromal cells - Transcription" 2 "HPA069392: AB_2686136, HPA077622: " "unprognostic (7.70e-2)" "unprognostic (6.70e-2)" "unprognostic (4.44e-2)" "unprognostic (3.14e-1)" MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 595.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 89.7;Enteroendocrine cells: 82.4;Hepatocytes: 198.8;Kupffer cells: 56.4;Proximal enterocytes: 92.5;Skeletal myocytes: 48.8" "Cancer enriched" "Detected in many" 6 "liver cancer: 60.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 83: Liver - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Hepatocytes - Metabolism" Nucleoplasm "HPA064640: AB_2685309" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.06e-3)" "unprognostic (3.46e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (6.13e-3)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (2.46e-2)" "unprognostic (7.72e-3)" MMEL1 "MMEL2, NEPII, NL1, NL2, SEP" ENSG00000142606 "Membrane metalloendopeptidase like 1" Q495T6 1 2590639-2633016 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 23.9" "Cell type enhanced" "Detected in many" "Early spermatids: 145.6;Late spermatids: 47.9;Paneth cells: 63.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "breast cancer: 1.9;prostate cancer: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007876, HPA008205, CAB020786" Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" "CAB020786: , HPA007876: AB_1854012, HPA008205: AB_1854011" "unprognostic (5.80e-2)" "unprognostic (4.61e-2)" "unprognostic (1.87e-1)" "unprognostic (4.27e-2)" "unprognostic (1.33e-1)" "unprognostic (2.71e-2)" "unprognostic (1.45e-1)" "unprognostic (7.96e-2)" "unprognostic (1.36e-2)" "unprognostic (2.37e-1)" "unprognostic (4.54e-3)" "unprognostic (2.44e-2)" "unprognostic (4.79e-2)" "unprognostic (3.18e-1)" "unprognostic (2.82e-1)" "unprognostic (2.18e-3)" "unprognostic (7.01e-4)" MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789401-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 73.2;stomach 1: 46.2;urinary bladder: 50.4" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 77.3;Cholangiocytes: 32.4;Ductal cells: 114.5;Exocrine glandular cells: 87.0;Pancreatic endocrine cells: 83.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Region enriched" "Detected in single" 7 "cerebral cortex: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 912.7;thyroid cancer: 1579.6" "Pancreas - Ductal cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "amygdala: 1.1;hippocampal formation: 4.0" HPA004920 Approved Vesicles "Secreted to extracellular matrix" Enzyme NA NA 7730000 55000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA004920: AB_2667293" "unprognostic (4.11e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavorable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770502-102780628 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "endometrium 1: 256.8" "Cell type enriched" "Detected in some" 17 "Basal respiratory cells: 3568.1" "Group enriched" "Detected in many" 4 "cervical cancer: 47.8;head and neck cancer: 102.2;lung cancer: 42.3" "Region enhanced" "Detected in some" "thalamus: 3.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "head and neck cancer: 33.9;Rhabdoid: 128.8;Sarcoma: 41.0" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Enzyme NA NA 765000 "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (8.76e-2)" "unprognostic (3.38e-1)" "unprognostic (1.98e-3)" "unprognostic (2.72e-3)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (5.67e-8)" "unprognostic (2.08e-3)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (6.99e-5)" "unprognostic (2.66e-2)" "unprognostic (7.98e-2)" "unprognostic (5.46e-2)" "prognostic favorable (7.12e-4)" MMP11 STMY3 ENSG00000099953 "Matrix metallopeptidase 11" P24347 22 23768226-23784316 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "cervix: 62.9;endometrium 1: 138.5;placenta: 38.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 74.0;Extravillous trophoblasts: 46.3;Fibroblasts: 17.8" "Cancer enhanced" "Detected in all" "pancreatic cancer: 119.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 4.5" "Lineage enriched" "Detected in single" 5 "dendritic cells: 4.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002593, HPA055204, HPA068864" Approved Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" Enzyme NA NA 640000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Non-specific - Transcription" "Cluster 9: Endometrial stromal cells - Transcription" "Golgi apparatus" Cytosol "CAB002593: , HPA055204: , HPA068864: AB_2686051" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.84e-3)" "unprognostic (2.77e-2)" "unprognostic (6.73e-2)" "unprognostic (2.14e-2)" "unprognostic (5.15e-1)" "unprognostic (2.73e-2)" "unprognostic (2.20e-1)" "unprognostic (1.89e-3)" "unprognostic (7.04e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (8.05e-2)" "unprognostic (6.78e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-2)" MMP12 HME ENSG00000262406 "Matrix metallopeptidase 12" P39900 11 102862736-102874982 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.2;lymphoid tissue: 39.3;urinary bladder: 15.5" "Group enriched" "Detected in some" 9 "Extravillous trophoblasts: 344.9;Langerhans cells: 117.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.7;head and neck cancer: 1.3;lymphoma: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 70: Lymphoid tissue - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 4: Extravillous trophoblasts - Unknown function" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" "unprognostic (1.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.69e-2)" "unprognostic (7.31e-2)" "unprognostic (1.52e-2)" "unprognostic (1.52e-3)" "unprognostic (5.45e-2)" "unprognostic (3.05e-6)" "unprognostic (1.08e-2)" "unprognostic (4.66e-2)" "unprognostic (1.73e-1)" "unprognostic (6.92e-2)" MMP13 CLG3 ENSG00000137745 "Matrix metallopeptidase 13" P45452 11 102942995-102955732 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "urinary bladder: 11.1" "Cell type enriched" "Detected in some" 16 "Basal respiratory cells: 370.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 70.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 46.7;thyroid cancer: 26.5" "Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB002742 Supported "Secreted to extracellular matrix" Enzyme NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "CAB002742: " "unprognostic (8.98e-3)" "unprognostic (1.54e-1)" "unprognostic (4.75e-2)" "unprognostic (4.57e-2)" "unprognostic (3.05e-2)" "unprognostic (1.59e-3)" "unprognostic (1.32e-1)" "unprognostic (6.35e-3)" "unprognostic (1.69e-1)" "unprognostic (7.55e-3)" "unprognostic (2.24e-1)" "unprognostic (1.73e-8)" "unprognostic (2.12e-2)" "unprognostic (3.14e-1)" "unprognostic (4.14e-2)" "unprognostic (4.33e-2)" MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.4" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 2254.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 11.0" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" Enzyme NA NA "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" MMP17 MT4-MMP ENSG00000198598 "Matrix metallopeptidase 17" Q9ULZ9 12 131828393-131851783 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 45.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.4;Inhibitory neurons: 13.6;Melanocytes: 41.2;monocytes: 21.7;Oligodendrocyte precursor cells: 25.0" "Cancer enriched" "Detected in many" 10 "melanoma: 29.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "skin cancer: 61.3" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (9.11e-2)" "unprognostic (1.27e-2)" "unprognostic (1.69e-2)" "unprognostic (3.71e-3)" "unprognostic (5.62e-2)" "unprognostic (1.85e-2)" "unprognostic (8.90e-3)" "unprognostic (2.14e-2)" "unprognostic (2.60e-1)" "unprognostic (2.66e-4)" "unprognostic (7.68e-2)" "unprognostic (5.88e-2)" "unprognostic (9.26e-10)" "unprognostic (1.15e-2)" "unprognostic (2.65e-1)" "unprognostic (1.21e-3)" "unprognostic (2.81e-2)" MMP19 "MMP18, RASI-1" ENSG00000123342 "Matrix metallopeptidase 19" Q99542 12 55835433-55842966 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Angiogenesis, Collagen degradation, Differentiation" "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 56.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 58.2;Fibroblasts: 53.4;Kupffer cells: 36.9;Langerhans cells: 98.2;Macrophages: 96.4;Mesothelial cells: 32.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "thalamus: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.9" "Breast - Adipocytes (Breast), Colon - Neutrophils" "Region enriched" "Detected in many" 5 "olfactory bulb: 7.2" "Low region specificity" "Detected in all" HPA070804 Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "Developmental protein" NA NA 2100000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 34: Testis cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" "Endoplasmic reticulum, Vesicles" "HPA070804: AB_2686315" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (2.28e-2)" "unprognostic (2.42e-1)" "unprognostic (4.77e-3)" "unprognostic (4.77e-3)" "unprognostic (2.01e-2)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (8.56e-9)" "unprognostic (5.06e-3)" "unprognostic (1.28e-3)" "unprognostic (2.73e-2)" "unprognostic (4.00e-2)" MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1025.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 219.7;Extravillous trophoblasts: 528.1;Fibroblasts: 757.2;Leydig cells: 332.5;Peritubular cells: 398.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 781.9" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" Enzyme NA NA 1600000000 220000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 5 Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" MMP20 ENSG00000137674 "Matrix metallopeptidase 20" O60882 11 102576832-102625332 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Amelogenesis imperfecta" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 18 "Early spermatids: 124.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lymphoma: 2.0;prostate cancer: 2.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 46: Lymphoma - Humoral immune response" "Cluster 18: Early spermatids - Unknown function" "unprognostic (4.62e-3)" "unprognostic (2.61e-2)" "unprognostic (1.68e-3)" "unprognostic (1.75e-1)" "unprognostic (2.13e-1)" "unprognostic (3.06e-1)" "unprognostic (2.97e-2)" "unprognostic (6.75e-2)" "unprognostic (9.58e-5)" "unprognostic (6.10e-2)" "unprognostic (2.35e-1)" MMP21 ENSG00000154485 "Matrix metallopeptidase 21" Q8N119 10 125753580-125775821 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" Heterotaxy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 16 "epididymis: 52.6" "Cell type enhanced" "Detected in some" "Early spermatids: 4.4;Late spermatids: 15.9;Ovarian stromal cells: 6.0;Rod photoreceptor cells: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 6: Ovarian stromal cells - Transcription" "unprognostic (1.32e-2)" "unprognostic (1.28e-1)" "unprognostic (8.51e-2)" "unprognostic (2.19e-2)" "unprognostic (4.02e-2)" "unprognostic (2.21e-2)" "unprognostic (4.22e-3)" "unprognostic (1.01e-1)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (2.89e-2)" "unprognostic (3.62e-2)" "unprognostic (9.70e-8)" "unprognostic (1.30e-2)" "unprognostic (7.69e-2)" "unprognostic (7.00e-2)" "unprognostic (2.18e-1)" MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226690-35276998 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 69.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 17.4;Excitatory neurons: 23.8;Horizontal cells: 15.1;Inhibitory neurons: 36.8;Mesothelial cells: 20.4;Oligodendrocyte precursor cells: 11.8;Oligodendrocytes: 11.2;Proximal tubular cells: 13.6" "Cancer enhanced" "Detected in many" "renal cancer: 11.4;testis cancer: 10.8" "Region enriched" "Detected in all" 4 "cerebellum: 88.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 30.5;Kidney cancer: 41.0" "Adipose visceral - Mesothelial cells, Colon - Smooth muscle cells, Pancreas - Ductal cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 68.1" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" Yes No "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (4.51e-4)" "unprognostic (2.47e-2)" "unprognostic (7.61e-3)" "unprognostic (1.22e-1)" "unprognostic (4.59e-2)" "unprognostic (2.32e-2)" "unprognostic (8.82e-2)" "unprognostic (9.20e-3)" "unprognostic (7.12e-2)" "prognostic favorable (8.17e-11)" "unprognostic (3.32e-2)" "unprognostic (5.63e-2)" "unprognostic (1.69e-2)" "unprognostic (9.90e-4)" MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.8;lymphoid tissue: 79.9" "Cell type enhanced" "Detected in some" "Kupffer cells: 3.8;Langerhans cells: 3.5;Macrophages: 4.1;Schwann cells: 4.3;Serous glandular cells: 4.3;T-cells: 4.2" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cancer enhanced" "Detected in some" "Leukemia: 2.6" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" Enzyme NA NA 120000 "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 74: Neutrophils - Degranulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" MMP26 "endometase, MGC126590, MGC126592" ENSG00000167346 "Matrix metallopeptidase 26" Q9NRE1 11 4704784-4992431 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "endometrium 1: 8.8" "Cell type enriched" "Detected in some" 11 "Glandular and luminal cells: 166.7" "Cancer enriched" "Detected in some" 4 "endometrial cancer: 8.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Glandular & Luminal cells - Unknown function" "unprognostic (4.21e-3)" "unprognostic (2.63e-1)" MMP27 ENSG00000137675 "Matrix metallopeptidase 27" Q9H306 11 102691487-102705769 "Enzymes, Predicted intracellular proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.5;salivary gland: 1.8;skin 1: 2.3" "Cell type enhanced" "Detected in some" "Fibroblasts: 3.4;Langerhans cells: 1.1;Melanocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Fibroblasts, Colon - Fibroblasts, Stomach - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" HPA069097 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 13: Skin - Cornification" "Cluster 60: Prostate cancer - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "HPA069097: AB_2686085" "unprognostic (3.99e-2)" "unprognostic (2.37e-4)" "unprognostic (1.25e-3)" "unprognostic (1.63e-1)" "unprognostic (4.60e-1)" MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 92.0;Alveolar cells type 2: 76.4;Distal enterocytes: 146.7;Paneth cells: 58.3;Proximal enterocytes: 77.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 55.6" "Breast - Adipocytes (Breast), Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 21: Testis - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 1 "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation, Immunity, Innate immunity" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 87.7;salivary gland: 277.6" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 19.9;Early spermatids: 31.2;Extravillous trophoblasts: 16.6;Fibroblasts: 51.3;Pancreatic endocrine cells: 17.0;Serous glandular cells: 11.0;Smooth muscle cells: 18.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Region enriched" "Detected in some" 5 "thalamus: 15.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Brain cancer: 71.9;Sarcoma: 120.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" Immunity NA NA 2540000 460000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 1 Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 492.8;salivary gland: 260.0;urinary bladder: 203.4" "Group enriched" "Detected in many" 5 "Ductal cells: 7365.3;Pancreatic endocrine cells: 4761.1" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 627.7;Uterine cancer: 461.4" "Liver - Cholangiocyte, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles,Cytosol "Secreted to extracellular matrix" Enzyme NA NA 2810000 35000 "Cluster 58: Placenta - Pregnancy" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Vesicles" Cytosol "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711796-102727050 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "bone marrow: 496.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 3.5;Macrophages: 1.4" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 1.7" "Cancer enriched" "Detected in some" 42 "skin cancer: 47.1" "Lung - Neutrophil_1, Thyroid - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA021763, HPA022935" Enhanced Approved Vesicles "Secreted to extracellular matrix" Enzyme NA NA 360000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 6: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 74: Neutrophils - Degranulation" Vesicles "HPA021221: AB_1854043, HPA021763: , HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" MMP9 CLG4B ENSG00000100985 "Matrix metallopeptidase 9" P14780 20 46008908-46016561 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "bone marrow: 372.5;lymphoid tissue: 102.8" "Group enriched" "Detected in many" 10 "Hofbauer cells: 223.7;Langerhans cells: 692.8;Macrophages: 337.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 10.9" "Immune cell enriched" "Detected in some" 127 "neutrophil: 272.9" "Lineage enriched" "Detected in single" 342 "granulocytes: 272.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.3" "Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000348, HPA001238, HPA063909, CAB068199, CAB068200, CAB068201" Enhanced Approved Cytosol "Secreted to blood" Enzyme NA NA 43300000 61000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 3 Cytosol "CAB000348: , CAB068199: AB_2665675, CAB068200: AB_2665676, CAB068201: AB_2665677, HPA001238: AB_1079398, HPA063909: AB_2685150" "unprognostic (4.62e-2)" "unprognostic (1.64e-1)" "unprognostic (2.85e-2)" "prognostic favorable (2.55e-4)" "unprognostic (6.65e-3)" "unprognostic (2.82e-1)" "prognostic unfavorable (7.19e-4)" "unprognostic (1.54e-1)" "unprognostic (8.57e-2)" "unprognostic (3.21e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (4.05e-5)" "unprognostic (4.65e-1)" "unprognostic (9.85e-3)" "unprognostic (2.48e-2)" "unprognostic (2.17e-3)" MMRN1 "ECM, EMILIN4, GPIa*, MMRN" ENSG00000138722 "Multimerin 1" Q13201 4 89879532-89954629 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 7 "Lymphatic endothelial cells: 1678.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "NK-cell: 6.3;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 9 "dendritic cells: 2.2;NK-cells: 6.3" "Cancer enhanced" "Detected in some" "Leukemia: 17.0;Rhabdoid: 13.3" "Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA035769 Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA 200000000 "Cluster 14: Non-specific - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Endoplasmic reticulum" "HPA035769: AB_10696511" "unprognostic (1.15e-1)" "unprognostic (1.81e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.11e-1)" "unprognostic (7.05e-3)" "unprognostic (1.62e-3)" "unprognostic (1.91e-1)" "unprognostic (1.88e-1)" "unprognostic (2.12e-1)" "unprognostic (9.71e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.77e-4)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.14e-1)" "unprognostic (1.36e-1)" "unprognostic (2.23e-2)" MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Adipocytes: 217.5;Endothelial cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 84000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 200.1" "Cell type enhanced" "Detected in some" "dendritic cells: 324.9;Hofbauer cells: 102.7;Kupffer cells: 424.4;Macrophages: 187.8;monocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 289.4;intermediate monocyte: 209.0;myeloid DC: 144.2;non-classical monocyte: 245.5;plasmacytoid DC: 204.5" "Group enriched" "Detected in many" 6 "dendritic cells: 204.5;monocytes: 289.4" "Group enriched" "Detected in some" 237 "Leukemia: 10.4;lymphoma: 36.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046801 Approved "Secreted to blood" Immunity NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" "HPA046801: AB_2679814" "unprognostic (1.24e-1)" "unprognostic (2.17e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-2)" "unprognostic (2.79e-3)" "unprognostic (7.82e-2)" "unprognostic (1.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-1)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" MPIG6B "C6orf25, G6b, G6b-B, NG31" ENSG00000204420 "Megakaryocyte and platelet inhibitory receptor G6b" O95866 6 31718594-31726714 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.7;skin 1: 8.0" "Cell type enhanced" "Detected in some" "dendritic cells: 11.9;Early spermatids: 4.6;Erythroid cells: 9.4;granulocytes: 23.5;Late spermatids: 11.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.6" "Adipose subcutaneous - Mast cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA054404, HPA073017" Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 330000 "Cluster 13: Skin - Cornification" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" "Golgi apparatus" "Nucleoplasm, Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA054404: , HPA073017: AB_2686566" "unprognostic (1.45e-1)" "unprognostic (1.25e-1)" "unprognostic (2.93e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" "unprognostic (6.53e-2)" "unprognostic (3.53e-2)" "unprognostic (2.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "unprognostic (2.70e-1)" "unprognostic (1.71e-2)" "unprognostic (1.82e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-2)" "unprognostic (1.71e-2)" MPO ENSG00000005381 Myeloperoxidase P05164 17 58269855-58280935 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 160 "bone marrow: 3400.6" "Cell type enriched" "Detected in some" 17 "Erythroid cells: 69.6" "Cancer enhanced" "Detected in single" "stomach cancer: 1.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 776 "Leukemia: 854.7" "Lung - Neutrophil_1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000059, HPA021147, HPA061464, CAB080352, CAB080353, CAB080354" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme No NA 576000000 24000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 2 Vesicles Nucleoplasm "CAB000059: AB_2335676, CAB080352: , CAB080353: , CAB080354: , HPA021147: AB_1854083, HPA061464: AB_2684531" "unprognostic (1.91e-1)" "unprognostic (9.08e-2)" "unprognostic (4.62e-2)" "unprognostic (2.90e-2)" "unprognostic (2.13e-3)" "unprognostic (2.78e-1)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (6.92e-2)" "unprognostic (8.34e-3)" "unprognostic (4.91e-2)" "unprognostic (3.07e-3)" "unprognostic (2.83e-1)" "unprognostic (1.14e-2)" "unprognostic (8.05e-2)" MR1 HLALS ENSG00000153029 "Major histocompatibility complex, class I-related" Q95460 1 181033374-181061938 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048304 Supported "Plasma membrane" "Intracellular and membrane" Immunity NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Non-specific - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 1 "Plasma membrane" "HPA048304: AB_2680347" "unprognostic (6.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.31e-2)" "unprognostic (1.96e-1)" "unprognostic (8.66e-3)" "unprognostic (4.37e-2)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.18e-1)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.05e-2)" "unprognostic (7.40e-3)" "unprognostic (4.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-2)" MRPL2 "CGI-22, MRP-L14, RPML14" ENSG00000112651 "Mitochondrial ribosomal protein L2" Q5T653 6 43054029-43059438 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007455, HPA064814" Approved Supported Nucleoplasm,Mitochondria "Intracellular and membrane" Other NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" Mitochondria Nucleoplasm "HPA007455: AB_1079410, HPA064814: AB_2685358" "unprognostic (2.31e-1)" "unprognostic (1.49e-2)" "unprognostic (3.06e-1)" "unprognostic (1.48e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-2)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (3.17e-1)" "prognostic favorable (6.01e-4)" "unprognostic (3.07e-1)" "unprognostic (1.79e-1)" "unprognostic (3.24e-2)" "unprognostic (6.42e-2)" "unprognostic (2.33e-2)" "unprognostic (3.13e-1)" "unprognostic (2.78e-1)" MRPL21 ENSG00000197345 "Mitochondrial ribosomal protein L21" Q7Z2W9 11 68891276-68903835 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051657 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Other NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA051657: AB_2681565" "unprognostic (1.80e-1)" "unprognostic (6.09e-2)" "unprognostic (4.80e-2)" "unprognostic (8.96e-3)" "unprognostic (9.25e-3)" "prognostic unfavorable (5.97e-4)" "unprognostic (3.23e-2)" "unprognostic (1.51e-1)" "unprognostic (1.09e-1)" "unprognostic (1.06e-1)" "unprognostic (4.84e-2)" "unprognostic (7.36e-2)" "unprognostic (1.26e-2)" "unprognostic (3.73e-2)" "unprognostic (1.72e-1)" "unprognostic (4.36e-2)" "unprognostic (3.12e-1)" MRPL24 MRP-L18 ENSG00000143314 "Mitochondrial ribosomal protein L24" Q96A35 1 156737303-156741590 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 226.7;Proximal tubular cells: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030295, HPA054323" Approved "Intracellular and membrane" Other NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA030295: AB_10600932, HPA054323: AB_2732583" "unprognostic (1.51e-1)" "unprognostic (1.52e-1)" "unprognostic (2.26e-2)" "unprognostic (1.47e-2)" "unprognostic (2.83e-1)" "unprognostic (3.69e-2)" "unprognostic (1.71e-2)" "unprognostic (3.11e-1)" "unprognostic (1.63e-1)" "unprognostic (5.80e-2)" "unprognostic (3.05e-3)" "unprognostic (2.73e-2)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.47e-1)" "unprognostic (8.75e-2)" "unprognostic (3.74e-1)" "unprognostic (1.94e-1)" MRPL27 ENSG00000108826 "Mitochondrial ribosomal protein L27" Q9P0M9 17 50367857-50373207 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 402.6;Proximal tubular cells: 407.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021416 Approved "Intracellular and membrane" Other NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 1 "HPA021416: AB_1854103" "unprognostic (2.09e-1)" "unprognostic (2.27e-2)" "unprognostic (4.66e-2)" "unprognostic (8.23e-2)" "unprognostic (2.10e-2)" "unprognostic (2.99e-2)" "unprognostic (7.03e-2)" "unprognostic (1.42e-1)" "unprognostic (8.79e-2)" "unprognostic (1.96e-2)" "unprognostic (2.43e-2)" "unprognostic (4.27e-2)" "unprognostic (1.65e-1)" "unprognostic (1.14e-1)" "unprognostic (7.61e-2)" "unprognostic (3.14e-2)" "unprognostic (7.76e-3)" MRPL32 "bMRP-59b, HSPC283, L32mt, MRP-L32" ENSG00000106591 "Mitochondrial ribosomal protein L32" Q9BYC8 7 42932376-42948958 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048965 Uncertain "Intracellular and membrane" Other NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 1 "HPA048965: AB_2680576" "unprognostic (1.15e-1)" "unprognostic (2.31e-1)" "unprognostic (3.82e-2)" "unprognostic (1.40e-1)" "unprognostic (5.90e-3)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-2)" "unprognostic (8.22e-3)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (5.05e-3)" "unprognostic (4.09e-2)" "unprognostic (1.43e-2)" "unprognostic (2.97e-1)" "unprognostic (2.21e-2)" MRPL35 ENSG00000132313 "Mitochondrial ribosomal protein L35" Q9NZE8 2 86199355-86213790 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043482 Uncertain "Intracellular and membrane" Other NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Mixed function" "HPA043482: AB_10959449" "unprognostic (3.68e-2)" "unprognostic (6.24e-2)" "unprognostic (9.14e-3)" "unprognostic (1.68e-2)" "unprognostic (9.38e-3)" "unprognostic (7.72e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.81e-2)" "unprognostic (1.76e-2)" "unprognostic (1.42e-2)" "unprognostic (1.62e-1)" "unprognostic (1.66e-1)" "prognostic favorable (9.96e-6)" "unprognostic (1.94e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (2.52e-3)" MRPL55 ENSG00000162910 "Mitochondrial ribosomal protein L55" Q7Z7F7 1 228106679-228109312 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027641 Supported "Intracellular and membrane" Other NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 43: Hepatocytes - Metabolism" "HPA027641: AB_10600825" "unprognostic (4.84e-2)" "unprognostic (3.63e-2)" "unprognostic (6.10e-3)" "unprognostic (3.03e-2)" "unprognostic (7.49e-2)" "unprognostic (2.71e-1)" "unprognostic (2.79e-1)" "unprognostic (1.22e-2)" "unprognostic (4.15e-1)" "prognostic favorable (6.76e-4)" "unprognostic (6.09e-3)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.62e-6)" "unprognostic (5.54e-2)" "unprognostic (8.23e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-1)" MRPS14 HSMRPS14 ENSG00000120333 "Mitochondrial ribosomal protein S14" O60783 1 175010789-175023425 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051087 Uncertain Supported "Nuclear membrane,Mitochondria" "Intracellular and membrane" Other NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" 3 Mitochondria "Nuclear membrane" "HPA051087: AB_2681339" "unprognostic (9.24e-2)" "unprognostic (6.37e-2)" "unprognostic (1.50e-1)" "unprognostic (3.46e-1)" "unprognostic (3.44e-2)" "unprognostic (5.39e-2)" "unprognostic (1.61e-2)" "unprognostic (3.01e-2)" "unprognostic (7.32e-2)" "unprognostic (4.85e-2)" "unprognostic (7.67e-2)" "unprognostic (3.10e-2)" "unprognostic (1.31e-3)" "unprognostic (1.67e-1)" "unprognostic (8.04e-2)" "unprognostic (2.42e-1)" "unprognostic (3.21e-2)" MRPS22 "C3orf5, GIBT, GK002, MRP-S22" ENSG00000175110 "Mitochondrial ribosomal protein S22" P82650 3 139005806-139360497 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006083, HPA007830" Enhanced Supported Mitochondria "Intracellular and membrane" Other NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mitochondria" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA006083: AB_1854122, HPA007830: AB_1854123" "unprognostic (8.38e-2)" "unprognostic (1.52e-2)" "unprognostic (3.04e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (5.22e-3)" "unprognostic (5.45e-3)" "unprognostic (4.85e-2)" "unprognostic (2.18e-2)" "unprognostic (2.78e-2)" "unprognostic (4.49e-3)" "prognostic unfavorable (1.55e-5)" "prognostic unfavorable (1.85e-4)" "unprognostic (3.22e-3)" "unprognostic (2.56e-2)" "unprognostic (1.49e-1)" "unprognostic (1.77e-1)" "unprognostic (3.40e-1)" MSH3 "DUP, MRP1" ENSG00000113318 "MutS homolog 3" P20585 5 80654652-80876815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036081 Approved "Nuclear bodies" "Intracellular and membrane" Other NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 7: Non-specific - Ribosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 3 "Nuclear bodies" "HPA036081: AB_10673229" "unprognostic (1.91e-1)" "unprognostic (7.61e-2)" "prognostic favorable (5.90e-5)" "unprognostic (2.95e-2)" "unprognostic (1.89e-1)" "unprognostic (6.41e-2)" "unprognostic (1.81e-1)" "unprognostic (8.70e-2)" "unprognostic (3.17e-2)" "unprognostic (2.62e-2)" "unprognostic (2.63e-1)" "unprognostic (3.91e-1)" "prognostic favorable (1.77e-4)" "unprognostic (5.15e-3)" "unprognostic (1.46e-1)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" MSLN "CAK1, MPF" ENSG00000102854 Mesothelin Q13421 16 760734-768865 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.4;fallopian tube: 268.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 344.4;Ionocytes: 378.5;Mesothelial cells: 758.3;Paneth cells: 198.8;Secretory cells: 822.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 343.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.9" "Group enriched" "Detected in many" 39 "dendritic cells: 5.9;monocytes: 1.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 100.1;pancreatic cancer: 97.1" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "spinal cord: 3.8" "CAB002216, HPA017172, CAB080356, CAB080357" Enhanced Supported "Vesicles,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 17000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 59: Fallopian tube - Tissue development" "Cluster 18: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" "Vesicles, Plasma membrane" "CAB002216: AB_563874, CAB080356: , CAB080357: , HPA017172: AB_1853819" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (3.95e-2)" "unprognostic (2.46e-1)" "unprognostic (9.47e-2)" "unprognostic (8.57e-2)" "unprognostic (4.69e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.63e-1)" "prognostic favorable (5.91e-4)" "unprognostic (2.00e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-2)" "unprognostic (3.35e-2)" MSMB "IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94" ENSG00000263639 "Microseminoprotein beta" P08118 10 46033307-46048180 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "prostate: 9036.6" "Cell type enriched" "Detected in many" 11 "Prostatic glandular cells: 29753.7" "Cancer enriched" "Detected in many" 42 "prostate cancer: 3435.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "prostate cancer: 295.9" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB026357, HPA051257" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 6000000 "Cluster 64: Neuronal - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "CAB026357: , HPA051257: AB_2681410" "unprognostic (6.47e-2)" "unprognostic (7.21e-3)" "unprognostic (1.37e-2)" "unprognostic (8.18e-3)" "unprognostic (4.28e-3)" "unprognostic (9.24e-3)" "unprognostic (1.66e-1)" "unprognostic (8.66e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (2.01e-1)" "unprognostic (7.04e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.19e-4)" MSMP "PC-3, PSMP" ENSG00000215183 "Microseminoprotein, prostate associated" Q1L6U9 9 35752990-35756613 "Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.2;pituitary gland: 1.5;placenta: 1.2" "Cell type enriched" "Detected in some" 8 "Late spermatids: 200.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "prostate cancer: 70.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA055174 Uncertain Supported Vesicles,Cytosol "Secreted in other tissues" Cytokine No No 30000 "Cluster 41: Basophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 11: Late spermatids - Unknown function" Vesicles Cytosol "HPA055174: AB_2682726" MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 83.6;liver: 62.4" "Cell type enhanced" "Detected in all" "Excitatory neurons: 605.0;Inhibitory neurons: 304.6;Oligodendrocyte precursor cells: 252.3;Proximal tubular cells: 522.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" Enzyme No No 55000 "Cluster 7: Non-specific - Innate immune response" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 5 "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" MSRB2 "CBS-1, CBS1, CGI-131, MSRB, PILB" ENSG00000148450 "Methionine sulfoxide reductase B2" Q9Y3D2 10 23095579-23122013 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 336.3;Proximal tubular cells: 422.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027933 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 40: Non-specific - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 9 "HPA027933: AB_10601867" "unprognostic (4.89e-2)" "unprognostic (2.76e-2)" "unprognostic (7.14e-3)" "unprognostic (3.47e-3)" "unprognostic (4.51e-1)" "unprognostic (9.26e-3)" "unprognostic (1.62e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (6.07e-3)" "unprognostic (3.47e-2)" "unprognostic (1.08e-2)" "unprognostic (2.03e-1)" "unprognostic (1.82e-2)" "unprognostic (6.74e-2)" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" MSRB3 "DFNB74, DKFZp686C1178, FLJ36866" ENSG00000174099 "Methionine sulfoxide reductase B3" Q8IXL7 12 65278643-65491430 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 231.9;Lymphatic endothelial cells: 90.4;Peritubular cells: 116.3;Smooth muscle cells: 156.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 41.8" "Lineage enhanced" "Detected in many" "granulocytes: 41.8" "Cancer enhanced" "Detected in all" "Rhabdoid: 95.9" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014432 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" 4 "HPA014432: AB_1854146" "unprognostic (1.40e-2)" "prognostic unfavorable (3.84e-4)" "unprognostic (2.86e-3)" "unprognostic (1.94e-1)" "unprognostic (2.74e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-2)" "unprognostic (5.33e-2)" "unprognostic (8.28e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (8.85e-8)" "unprognostic (3.29e-3)" "unprognostic (7.80e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (2.17e-4)" MST1 "D3F15S2, DNF15S2, HGFL, MSP, NF15S2" ENSG00000173531 "Macrophage stimulating 1" 3 49683947-49689501 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "liver: 905.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 196.0;Mesothelial cells: 44.6;Proximal enterocytes: 54.0;Proximal tubular cells: 42.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024036, HPA068514, CAB080358" Approved Approved Vesicles "Secreted to blood" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" Vesicles "CAB080358: , HPA024036: AB_1854147, HPA068514: " "unprognostic (5.13e-3)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (1.16e-2)" "unprognostic (9.42e-3)" "unprognostic (8.24e-2)" "unprognostic (2.97e-1)" "prognostic favorable (7.14e-4)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" MSTN GDF8 ENSG00000138379 Myostatin O14793 2 190055700-190062729 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 9.7;tongue: 14.7" "Cell type enhanced" "Detected in some" "Early spermatids: 19.4;Late spermatids: 7.1;Muller glia cells: 17.2;Schwann cells: 4.0;Skeletal myocytes: 3.9" "Cancer enriched" "Detected in some" 9 "glioma: 6.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Sarcoma: 18.2" "Colon - Enteric glia cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009963 Approved "Secreted in other tissues" Cytokine NA NA 7600000 "Cluster 3: Non-specific - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 53: Fibroblasts - ECM organization" 4 "CAB009963: AB_2148798" "unprognostic (8.45e-2)" "unprognostic (2.84e-2)" "unprognostic (3.52e-2)" "unprognostic (2.54e-1)" "prognostic favorable (2.86e-4)" "unprognostic (7.59e-3)" "unprognostic (2.95e-1)" "unprognostic (4.09e-2)" "unprognostic (1.91e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-3)" "unprognostic (7.72e-3)" "unprognostic (1.12e-4)" "unprognostic (1.06e-1)" "unprognostic (3.94e-1)" "unprognostic (6.53e-2)" "unprognostic (5.67e-4)" MTHFD2 ENSG00000065911 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" P13995 2 74186172-74217565 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 275.1;Smooth muscle cells: 162.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003684, HPA049657" Approved Supported Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 18: Non-specific - Ribosome" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 13: Non-specific - Mixed function" "Cluster 48: Smooth muscle cells - Signal transduction" Mitochondria "CAB003684: AB_425867, HPA049657: AB_2680842" "unprognostic (1.82e-3)" "unprognostic (4.60e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (2.07e-5)" "prognostic favorable (1.01e-4)" "unprognostic (3.10e-3)" "unprognostic (2.24e-3)" "unprognostic (4.75e-3)" "unprognostic (2.64e-2)" "unprognostic (3.96e-2)" "unprognostic (3.76e-3)" "unprognostic (3.57e-3)" "prognostic unfavorable (1.11e-16)" "unprognostic (3.66e-2)" "unprognostic (6.52e-2)" "unprognostic (9.07e-2)" "unprognostic (2.34e-3)" MTMR14 "C3orf29, FLJ22405, FLJ90311, hEDTP, hJumpy" ENSG00000163719 "Myotubularin related protein 14" Q8NCE2 3 9649433-9702393 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054063 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" "HPA054063: AB_2682365" "unprognostic (9.50e-2)" "unprognostic (5.60e-3)" "unprognostic (9.28e-2)" "unprognostic (1.31e-1)" "unprognostic (8.81e-3)" "unprognostic (2.34e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (2.42e-1)" "unprognostic (2.00e-1)" "unprognostic (3.51e-3)" "unprognostic (7.04e-2)" "unprognostic (1.37e-1)" "prognostic favorable (2.74e-4)" "unprognostic (1.25e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-1)" "unprognostic (1.01e-3)" MTTP "ABL, MTP" ENSG00000138823 "Microsomal triglyceride transfer protein" P55157 4 99564081-99623997 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 267.5;liver: 258.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 206.9;Muller glia cells: 127.4;Proximal enterocytes: 560.1" "Cancer enriched" "Detected in many" 13 "liver cancer: 28.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Gastric cancer: 5.1;liver cancer: 18.2" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA051170, HPA054862" Uncertain Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Transport NA NA 640000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 1 "Endoplasmic reticulum, Cytosol" "HPA051170: , HPA054862: AB_2682628" "unprognostic (1.66e-2)" "unprognostic (1.14e-1)" "unprognostic (5.64e-2)" "unprognostic (5.33e-2)" "unprognostic (3.49e-3)" "unprognostic (7.38e-2)" "unprognostic (1.05e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (3.66e-2)" "unprognostic (1.00e-2)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (2.02e-2)" "unprognostic (3.64e-1)" "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" MTX2 ENSG00000128654 "Metaxin 2" O75431 2 176269395-176338025 "Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 237.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031550, HPA031551, HPA031552" Approved Approved Supported Nucleoli,Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 31: Spermatocytes - Spermatogenesis" 4 Mitochondria Nucleoli "HPA031550: AB_10599733, HPA031551: AB_10601442, HPA031552: AB_10794616" "unprognostic (2.61e-1)" "unprognostic (9.86e-2)" "unprognostic (6.54e-2)" "prognostic unfavorable (5.06e-4)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "unprognostic (2.87e-2)" "unprognostic (3.97e-2)" "unprognostic (1.80e-2)" "unprognostic (8.30e-2)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (9.92e-2)" "unprognostic (3.15e-2)" "unprognostic (1.33e-2)" MUC1 "ADMCKD, ADMCKD1, Ca15-3, CD227, EMA, KL-6, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 419.1;stomach 1: 862.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 963.7;Alveolar cells type 2: 1456.7;Exocrine glandular cells: 951.7;Gastric mucus-secreting cells: 572.5;Ionocytes: 447.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Cancer enhanced" "Detected in all" "breast cancer: 211.1;pancreatic cancer: 218.2" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Mitotic cells (Colon), Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855, CAB080102, CAB080103" Enhanced Supported "Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA 4000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , CAB080102: , CAB080103: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" MUC13 DRCC1 ENSG00000173702 "Mucin 13, cell surface associated" Q9H3R2 3 124905442-124953819 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 597.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 500.9;Enteroendocrine cells: 161.4;Intestinal goblet cells: 447.1;Paneth cells: 323.4;Proximal enterocytes: 400.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 198.4;stomach cancer: 152.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 178.0;Gastric cancer: 65.7" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045163, HPA079663" Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA045163: AB_10960396, HPA079663: " "unprognostic (8.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-3)" "unprognostic (2.93e-1)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-2)" "unprognostic (2.94e-1)" "unprognostic (5.10e-2)" "unprognostic (2.02e-1)" "unprognostic (9.64e-2)" "prognostic unfavorable (9.73e-5)" "unprognostic (2.05e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" MUC15 ENSG00000169550 "Mucin 15, cell surface associated" Q8N387 11 26559032-26572263 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "epididymis: 1903.7" "Cell type enriched" "Detected in many" 9 "Syncytiotrophoblasts: 952.8" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 56.7" "Region enhanced" "Detected in many" "basal ganglia: 10.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Group enriched" "Detected in some" 4 "cerebellum: 1.2;thalamus: 1.4" "Low region specificity" "Detected in all" "HPA026110, HPA073304" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 3 "HPA026110: AB_1854200, HPA073304: " "unprognostic (1.49e-1)" "unprognostic (2.08e-3)" "unprognostic (7.71e-5)" "unprognostic (5.09e-3)" "unprognostic (2.77e-2)" "unprognostic (3.04e-2)" "unprognostic (6.58e-2)" "unprognostic (1.12e-1)" "unprognostic (9.44e-3)" "unprognostic (1.98e-1)" "unprognostic (7.27e-3)" "unprognostic (4.96e-3)" "unprognostic (1.09e-1)" "unprognostic (5.70e-2)" "unprognostic (4.54e-3)" MUC16 "CA-125, CA125, FLJ14303" ENSG00000181143 "Mucin 16, cell surface associated" Q8WXI7 19 8848844-8981342 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 7.0;cervix: 15.4;fallopian tube: 5.7;salivary gland: 5.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 157.5;Club cells: 88.3;Glandular and luminal cells: 170.2;Ionocytes: 224.9;Mesothelial cells: 429.4;Salivary duct cells: 117.9" "Cancer enriched" "Detected in many" 4 "ovarian cancer: 21.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 15.7" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.3" "CAB055172, HPA065600, CAB080360" Enhanced "Secreted in other tissues" "No annotated function" NA NA 25000 "Cluster 62: Connective tissue - ECM organization" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" "CAB055172: AB_2148831, CAB080360: , HPA065600: AB_2732736" "unprognostic (8.66e-2)" "unprognostic (3.89e-2)" "unprognostic (5.37e-2)" "unprognostic (3.07e-1)" "unprognostic (1.76e-2)" "unprognostic (3.01e-3)" "unprognostic (3.83e-3)" "unprognostic (1.31e-2)" "unprognostic (1.00e-2)" "unprognostic (1.86e-1)" "unprognostic (1.89e-3)" "unprognostic (1.81e-1)" "unprognostic (2.60e-8)" "unprognostic (3.50e-2)" "unprognostic (2.86e-1)" "unprognostic (1.43e-1)" "unprognostic (3.68e-3)" MUC17 ENSG00000169876 "Mucin 17, cell surface associated" Q685J3 7 101020072-101058859 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 62 "intestine: 41.5" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 309.8" "Cancer enhanced" "Detected in some" "stomach cancer: 22.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 3.3;colorectal cancer: 5.7;Gastric cancer: 10.4;pancreatic cancer: 4.1" "Colon - Colon enterocytes" "Not detected" "Not detected" HPA031634 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA031634: AB_10603021" "unprognostic (2.37e-2)" "unprognostic (2.41e-1)" "unprognostic (8.17e-3)" "unprognostic (5.57e-3)" "unprognostic (6.07e-2)" "unprognostic (8.79e-8)" "unprognostic (1.28e-1)" "unprognostic (2.47e-2)" MUC19 FLJ35746 ENSG00000205592 "Mucin 19, oligomeric" 12 40393395-40570832 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 18 "salivary gland: 3.2;testis: 1.0" "Group enriched" "Detected in some" 7 "Early spermatids: 33.3;Late spermatids: 22.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "breast cancer: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 27: Breast cancer - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" "unprognostic (7.80e-3)" "unprognostic (2.84e-1)" "unprognostic (1.69e-1)" "unprognostic (2.53e-1)" "unprognostic (4.25e-3)" "unprognostic (8.16e-2)" "unprognostic (1.27e-1)" "unprognostic (5.45e-2)" "unprognostic (8.63e-2)" "unprognostic (6.99e-2)" "unprognostic (8.64e-3)" "unprognostic (2.57e-2)" "unprognostic (1.60e-1)" "unprognostic (2.12e-1)" "unprognostic (7.35e-3)" MUC2 ENSG00000198788 "Mucin 2, oligomeric mucus/gel-forming" 11 1074875-1110511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 129.5" "Cell type enriched" "Detected in some" 45 "Intestinal goblet cells: 7119.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 93.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 1.6;colorectal cancer: 4.2;Gastric cancer: 2.3" "Colon - Colon enterocytes" "Not detected" "Not detected" CAB016275 Enhanced "Intracellular and membrane" NA NA "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "CAB016275: AB_627970" "unprognostic (6.37e-2)" "unprognostic (8.32e-2)" "unprognostic (5.76e-3)" "unprognostic (5.09e-2)" "unprognostic (6.18e-3)" "unprognostic (3.39e-2)" "unprognostic (1.71e-2)" "unprognostic (5.76e-3)" "unprognostic (7.87e-2)" "unprognostic (2.04e-1)" "unprognostic (7.37e-3)" "unprognostic (4.20e-2)" "unprognostic (3.64e-5)" "unprognostic (1.38e-1)" "unprognostic (1.22e-1)" "unprognostic (3.10e-2)" MUC20 "FLJ14408, KIAA1359" ENSG00000176945 "Mucin 20, cell surface associated" Q8N307 3 195720884-195741123 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Club cells: 44.7;Distal enterocytes: 52.8;Ductal cells: 72.1;Ionocytes: 50.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA042249 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" "No annotated function" NA NA 170000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042249: " "unprognostic (1.85e-1)" "unprognostic (4.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.83e-3)" "unprognostic (2.12e-1)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (2.41e-1)" "unprognostic (3.99e-4)" "unprognostic (7.66e-2)" "unprognostic (2.84e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.57e-4)" "unprognostic (2.05e-1)" "unprognostic (2.56e-1)" "unprognostic (3.98e-3)" "unprognostic (1.17e-1)" MUC3A MUC3 ENSG00000169894 "Mucin 3A, cell surface associated" Q02505 7 100949534-100968347 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 13.4;intestine: 40.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 179.2;Intestinal goblet cells: 179.0;Paneth cells: 140.9;Proximal enterocytes: 383.1;Undifferentiated cells: 115.8" "Group enriched" "Detected in many" 5 "colorectal cancer: 16.4;pancreatic cancer: 14.0;stomach cancer: 29.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 8.3;Gastric cancer: 3.8" "Region enriched" "Detected in many" 7 "cerebellum: 16.5" "HPA010871, HPA047868" Uncertain Uncertain "Cell Junctions" "Intracellular and membrane" "No annotated function" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 1: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "Cell Junctions" "HPA010871: AB_1854201, HPA047868: " "unprognostic (1.12e-2)" "unprognostic (3.78e-2)" "unprognostic (1.75e-1)" "unprognostic (4.22e-3)" "unprognostic (2.91e-1)" "unprognostic (5.16e-2)" "unprognostic (2.06e-1)" "unprognostic (5.29e-3)" "unprognostic (2.87e-1)" "unprognostic (1.33e-1)" "unprognostic (7.01e-2)" "unprognostic (2.99e-1)" "unprognostic (6.50e-3)" "unprognostic (8.73e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (4.51e-2)" MUC4 ENSG00000145113 "Mucin 4, cell surface associated" Q99102 3 195746765-195811973 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 18.6;intestine: 30.3;prostate: 14.4;vagina: 14.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 85.3;Ciliated cells: 204.0;Club cells: 215.4;Distal enterocytes: 188.3;Gastric mucus-secreting cells: 144.4;Intestinal goblet cells: 131.1;Ionocytes: 305.6;Salivary duct cells: 110.2" "Cancer enhanced" "Detected in many" "cervical cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 3.4;head and neck cancer: 4.1;pancreatic cancer: 3.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 18 "basal ganglia: 5.4" "HPA005895, CAB013536" Approved "Secreted in other tissues" "Cell adhesion" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "CAB013536: , HPA005895: AB_1079427" "unprognostic (4.16e-3)" "unprognostic (1.00e-2)" "unprognostic (6.79e-2)" "unprognostic (1.11e-2)" "unprognostic (3.03e-2)" "unprognostic (5.16e-2)" "unprognostic (5.49e-2)" "unprognostic (2.74e-1)" "unprognostic (3.19e-1)" "unprognostic (4.22e-3)" "unprognostic (6.68e-3)" "unprognostic (5.30e-2)" "unprognostic (2.43e-3)" "unprognostic (3.19e-1)" "unprognostic (6.78e-2)" "unprognostic (3.46e-3)" "unprognostic (9.97e-3)" MUC5AC MUC5 ENSG00000215182 "Mucin 5AC, oligomeric mucus/gel-forming" P98088 11 1157953-1201138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "stomach 1: 180.4" "Cell type enriched" "Detected in some" 34 "Gastric mucus-secreting cells: 8881.6" "Group enriched" "Detected in many" 4 "pancreatic cancer: 25.3;stomach cancer: 61.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 27.8;pancreatic cancer: 16.8" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002774, CAB009395, HPA040456, HPA040615, HPA070378, HPA077637" Enhanced Uncertain Vesicles "Secreted to digestive system" "No annotated function" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 46: Gastric mucus-secreting cells - Digestion" Vesicles "CAB002774: , CAB009395: AB_2146854, HPA040456: , HPA040615: AB_2677042, HPA070378: , HPA077637: " "unprognostic (2.10e-2)" "unprognostic (1.11e-1)" "unprognostic (1.27e-1)" "unprognostic (3.14e-2)" "unprognostic (1.72e-2)" "unprognostic (2.51e-2)" "unprognostic (4.56e-2)" "unprognostic (6.49e-2)" "unprognostic (2.44e-2)" "unprognostic (1.30e-3)" "unprognostic (8.46e-2)" "unprognostic (5.83e-4)" "unprognostic (1.84e-1)" "unprognostic (9.21e-3)" "unprognostic (4.07e-1)" "unprognostic (1.37e-1)" MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "salivary gland: 2543.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 490.3;Club cells: 150.9;Distal enterocytes: 142.5;Intestinal goblet cells: 123.5;Ionocytes: 88.0;Undifferentiated cells: 78.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 23.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" "No annotated function" NA NA 1300000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Vesicles "CAB009396: AB_2282256, HPA008246: AB_1854203" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (2.76e-3)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.89e-2)" "unprognostic (7.80e-3)" "unprognostic (3.75e-1)" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (8.95e-2)" "unprognostic (2.57e-7)" "unprognostic (2.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" MUC6 ENSG00000184956 "Mucin 6, oligomeric mucus/gel-forming" Q6W4X9 11 1012823-1036718 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "pancreas: 166.3;stomach 1: 398.8" "Group enriched" "Detected in some" 6 "Basal prostatic cells: 289.9;Gastric mucus-secreting cells: 279.4" "Group enriched" "Detected in many" 4 "pancreatic cancer: 42.9;stomach cancer: 58.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 15 "basal ganglia: 25.8" CAB002165 Enhanced "Secreted to digestive system" "No annotated function" NA NA 75000 "Cluster 15: Pancreas - Proteolysis" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 3: Basal prostatic cells - Lipid metabolism" "CAB002165: AB_442114" "unprognostic (1.90e-2)" "unprognostic (1.00e-1)" "unprognostic (5.21e-3)" "unprognostic (1.56e-3)" "unprognostic (1.04e-1)" "unprognostic (5.17e-3)" "unprognostic (2.17e-1)" "unprognostic (1.48e-1)" "unprognostic (1.65e-2)" "unprognostic (2.63e-1)" "unprognostic (9.46e-2)" "unprognostic (8.62e-2)" "unprognostic (3.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (4.72e-2)" "unprognostic (5.23e-2)" MUC7 "FLJ27047, MG2" ENSG00000171195 "Mucin 7, secreted" Q8TAX7 4 70430492-70482997 "Disease related genes, Human disease related genes, Predicted secreted proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 877 "salivary gland: 25265.8" "Cell type enriched" "Detected in some" 16 "Mucus glandular cells: 4614.8" "Group enriched" "Detected in some" 12 "head and neck cancer: 8.1;melanoma: 2.1" "Region enhanced" "Detected in single" "midbrain: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "skin cancer: 1.4" "Skin - Eccrine sweat gland cells" HPA006411 Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 75: Serous glandular cells - Salivary secretion" 4 "HPA006411: AB_1854204" "unprognostic (5.49e-2)" "unprognostic (3.20e-1)" "unprognostic (1.06e-1)" MUCL1 SBEM ENSG00000172551 "Mucin like 1" Q96DR8 12 54830518-54896008 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 3139.6" "Group enriched" "Detected in some" 9 "Breast glandular cells: 4271.1;Breast myoepithelial cells: 1169.0;Melanocytes: 3047.5" "Cancer enriched" "Detected in many" 30 "breast cancer: 298.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 40 "breast cancer: 270.9" HPA039093 Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 73: Breast - Lactation" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 1 "HPA039093: AB_10795577" "unprognostic (2.26e-1)" "unprognostic (3.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.47e-1)" "unprognostic (2.53e-1)" "unprognostic (8.34e-3)" "unprognostic (5.55e-2)" "unprognostic (2.00e-1)" "unprognostic (3.11e-2)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.04e-1)" "unprognostic (9.90e-2)" MXRA5 DKFZp564I1922 ENSG00000101825 "Matrix remodeling associated 5" Q9NR99 X 3308565-3346652 "Cancer-related genes, Disease related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 33.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 22.6;Basal prostatic cells: 29.9;Collecting duct cells: 27.2;Exocrine glandular cells: 66.0;Fibroblasts: 47.9;Salivary duct cells: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 42.4" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skin - Fibroblast_1" "HPA000508, HPA076518" Uncertain Uncertain Mitochondria "Secreted to extracellular matrix" "No annotated function" NA NA 2600000 "Cluster 13: Skin - Cornification" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Mitochondria "HPA000508: AB_2147995, HPA076518: " "unprognostic (7.51e-2)" "unprognostic (6.45e-2)" "unprognostic (8.00e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (7.05e-2)" "unprognostic (7.25e-2)" "unprognostic (1.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-2)" "unprognostic (6.32e-3)" "unprognostic (1.38e-1)" "unprognostic (1.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (8.94e-4)" MXRA7 "FLJ46603, PS1TP1, TMAP1" ENSG00000182534 "Matrix remodeling associated 7" P84157 17 76672551-76711004 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 285.2;Cone photoreceptor cells: 169.9;Endometrial stromal cells: 190.1;Muller glia cells: 314.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "HPA044819, HPA075316" Uncertain Enhanced "Endoplasmic reticulum" "Secreted to blood" "No annotated function" NA NA 100000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "HPA044819: AB_10964134, HPA075316: " "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.32e-1)" "unprognostic (2.92e-1)" "unprognostic (1.19e-1)" "unprognostic (3.16e-2)" "prognostic unfavorable (4.70e-4)" "unprognostic (3.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.51e-3)" "unprognostic (2.07e-2)" "unprognostic (8.33e-2)" "unprognostic (5.39e-3)" "unprognostic (4.67e-3)" "unprognostic (6.21e-2)" "unprognostic (4.63e-3)" "prognostic unfavorable (1.80e-5)" MYCBP2 "FLJ10106, KIAA0916, PAM, PHR1" ENSG00000005810 "MYC binding protein 2" O75592 13 77042474-77327094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 411.2;Inhibitory neurons: 451.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058807 Supported Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 13: Skin - Cornification" "Cluster 14: Neurons - Synaptic function" "Cluster 19: Non-specific - Unknown function" "Cluster 73: B-cells - B-cell function" 3 Nucleoplasm "Vesicles, Cytosol" "HPA058807: AB_2732627" "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (8.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (6.42e-2)" "prognostic favorable (5.01e-5)" "unprognostic (2.63e-1)" "unprognostic (9.84e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" MYDGF "C19orf10, IL-25, IL-27, IL25, IL27, IL27w, R33729_1, SF20" ENSG00000074842 "Myeloid derived growth factor" Q969H8 19 4641374-4670362 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 894.3;Plasma cells: 991.6;Syncytiotrophoblasts: 622.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041872, HPA046744" Approved "Secreted to blood" "Developmental protein" NA NA 285000 2100000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 12 "HPA041872: AB_2677718, HPA046744: AB_2679783" "unprognostic (3.14e-1)" "unprognostic (1.32e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.50e-7)" "unprognostic (4.14e-1)" "unprognostic (1.35e-1)" "unprognostic (1.08e-2)" "unprognostic (1.71e-1)" "unprognostic (5.11e-2)" "unprognostic (4.56e-2)" "unprognostic (8.19e-2)" "unprognostic (4.54e-2)" "prognostic unfavorable (4.99e-12)" "unprognostic (4.42e-1)" "unprognostic (3.24e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" MYG1 "C12orf10, Gamm1, MYG" ENSG00000139637 "MYG1 exonuclease" Q9HB07 12 53299695-53307177 "Disease related genes, Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.2;Inhibitory neurons: 8.3;Oligodendrocytes: 6.9;Pancreatic endocrine cells: 8.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038626, HPA038627" Approved Supported Supported Nucleoplasm "Intracellular and membrane" Enzyme NA NA 20000 "Cluster 33: Non-specific - ATP binding" "Cluster 78: Testis - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" 35 Nucleoplasm "HPA038626: AB_10674692, HPA038627: AB_2676123" "unprognostic (5.33e-2)" "unprognostic (4.41e-2)" "unprognostic (6.77e-2)" "unprognostic (2.44e-2)" "unprognostic (3.59e-1)" "unprognostic (7.56e-2)" "unprognostic (1.61e-3)" "unprognostic (2.73e-1)" "unprognostic (1.97e-1)" "unprognostic (3.58e-2)" "unprognostic (2.71e-2)" "unprognostic (1.39e-1)" "unprognostic (2.81e-1)" "unprognostic (6.41e-2)" "unprognostic (2.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.61e-1)" MYL1 "MLC-1, MLC1, MLC1/3, MLC1F, MLC3F" ENSG00000168530 "Myosin light chain 1" P05976 2 210290150-210315174 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 87 "skeletal muscle: 21042.5;tongue: 14976.0" "Cell type enriched" "Detected in some" 3668 "Skeletal myocytes: 6375.9" "Group enriched" "Detected in some" 18 "head and neck cancer: 36.0;prostate cancer: 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "Sarcoma: 37.9" "Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.0" "Low region specificity" "Detected in all" "HPA046859, HPA063034, HPA073827" Enhanced "Intracellular and membrane" Other NA NA 21000000 "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 2: Skeletal myocytes - Muscle contraction" "HPA046859: AB_2679842, HPA063034: AB_2684927, HPA073827: " "prognostic unfavorable (6.59e-4)" "unprognostic (1.88e-1)" MYOC "GLC1A, JOAG1, TIGR" ENSG00000034971 Myocilin Q99972 1 171635417-171652688 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 106.5" "Cell type enriched" "Detected in some" 4 "Fibroblasts: 184.6" "Cancer enriched" "Detected in many" 6 "melanoma: 13.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 45 "Rhabdoid: 209.3" "Colon - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA027364 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 25000000 "Cluster 35: Non-specific - Mitochondria" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 4 "HPA027364: AB_10602036" "unprognostic (2.02e-2)" "unprognostic (4.65e-2)" "unprognostic (4.44e-2)" "unprognostic (6.29e-2)" "unprognostic (1.43e-1)" "unprognostic (2.33e-2)" "unprognostic (3.42e-2)" "unprognostic (3.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.54e-1)" "unprognostic (1.94e-4)" "unprognostic (5.35e-2)" "unprognostic (1.87e-1)" "unprognostic (3.87e-2)" "unprognostic (1.24e-1)" MYRFL "bcm1377, C12orf15, C12orf28, FLJ25056" ENSG00000166268 "Myelin regulatory factor like" Q96LU7 12 69825227-69959097 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 22.3" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 98.3;Late spermatids: 30.4;Oligodendrocyte precursor cells: 66.0;Proximal enterocytes: 32.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA049340 Approved Approved Nucleoli "Intracellular and membrane" Other NA NA "Cluster 25: Small intestine - Absorption" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" Nucleoli "HPA049340: AB_2680719" "unprognostic (2.95e-2)" "unprognostic (6.25e-2)" "unprognostic (2.49e-2)" "unprognostic (1.42e-1)" "unprognostic (5.18e-2)" "unprognostic (2.34e-1)" "unprognostic (5.45e-2)" "unprognostic (6.50e-2)" "unprognostic (3.37e-1)" "unprognostic (2.65e-1)" "unprognostic (3.08e-1)" "unprognostic (8.99e-2)" "unprognostic (1.91e-2)" "unprognostic (3.89e-2)" "unprognostic (2.07e-2)" "unprognostic (1.17e-1)" "unprognostic (9.96e-2)" MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 87.2;lymphoid tissue: 265.7" "Cell type enriched" "Detected in many" 9 "Plasma cells: 4495.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "memory B-cell: 160.8;plasmacytoid DC: 570.5" "Group enriched" "Detected in many" 115 "B-cells: 160.8;dendritic cells: 570.5" "Cancer enriched" "Detected in some" 5 "Myeloma: 759.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Pancreas - Plasma cells, Skeletal muscle - Plasma cells, Skin - Plasma cells, Stomach - Plasma cells, Thyroid - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" Other NA NA 350000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 1 "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" NAA38 "LSMD1, MGC14151, PFAAP2" ENSG00000183011 "N-alpha-acetyltransferase 38, NatC auxiliary subunit" Q9BRA0 17 7856685-7885238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1636.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059189 Supported Nucleoplasm "Intracellular and membrane" "No annotated function" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 5 Nucleoplasm "HPA059189: " "unprognostic (6.84e-2)" "unprognostic (1.65e-3)" "unprognostic (1.30e-2)" "unprognostic (1.85e-3)" "unprognostic (2.76e-2)" "unprognostic (3.35e-1)" "unprognostic (4.72e-2)" "unprognostic (1.05e-1)" "unprognostic (2.27e-1)" "unprognostic (7.28e-3)" "unprognostic (1.48e-3)" "unprognostic (3.31e-1)" "unprognostic (5.83e-3)" "unprognostic (1.58e-1)" "unprognostic (6.02e-2)" "unprognostic (2.66e-1)" "unprognostic (9.75e-2)" NAAA ASAHL ENSG00000138744 "N-acylethanolamine acid amidase" Q02083 4 75913660-75941013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 204.2;Prostatic glandular cells: 147.2;Proximal enterocytes: 149.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 31.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 671.9;non-classical monocyte: 585.2" "Lineage enriched" "Detected in all" 5 "monocytes: 671.9" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026135 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" "CAB026135: " "unprognostic (5.30e-3)" "unprognostic (1.23e-2)" "unprognostic (1.41e-2)" "prognostic favorable (1.93e-4)" "unprognostic (1.10e-1)" "unprognostic (2.17e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-2)" "unprognostic (2.24e-1)" "unprognostic (2.87e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.63e-1)" "unprognostic (2.15e-2)" "unprognostic (2.54e-1)" "unprognostic (3.20e-2)" "unprognostic (3.42e-3)" "unprognostic (6.21e-2)" NAGA D22S674 ENSG00000198951 Alpha-N-acetylgalactosaminidase P17050 22 42058334-42070842 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 69.5;Hofbauer cells: 93.9;monocytes: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 202.7;intermediate monocyte: 249.1;myeloid DC: 195.3;non-classical monocyte: 259.0;plasmacytoid DC: 120.0" "Group enriched" "Detected in all" 6 "dendritic cells: 195.3;monocytes: 259.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000649 Enhanced "Intracellular and membrane" Enzyme NA NA 2200000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "HPA000649: AB_1079448" "unprognostic (3.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.45e-3)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (4.27e-1)" "unprognostic (1.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.93e-1)" "unprognostic (3.64e-2)" "unprognostic (3.68e-2)" "unprognostic (1.92e-3)" "unprognostic (8.95e-2)" "unprognostic (2.53e-1)" NAGLU NAG ENSG00000108784 N-acetyl-alpha-glucosaminidase P54802 17 42536241-42544449 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Charcot-Marie-Tooth disease, Disease variant, Mucopolysaccharidosis, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038815 Supported "Intracellular and membrane" Enzyme NA NA 270000000 "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" "HPA038815: AB_10697398" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (6.48e-2)" "prognostic favorable (4.17e-4)" "prognostic unfavorable (6.59e-4)" "unprognostic (1.46e-1)" "unprognostic (1.75e-3)" "unprognostic (3.09e-2)" "unprognostic (2.20e-1)" "unprognostic (6.68e-2)" "prognostic favorable (6.90e-4)" "unprognostic (8.07e-2)" "prognostic favorable (2.58e-6)" "unprognostic (2.25e-1)" "unprognostic (8.74e-3)" "unprognostic (2.15e-2)" "unprognostic (1.62e-1)" NAGS "AGAS, ARGA, NAT7" ENSG00000161653 "N-acetylglutamate synthase" Q8N159 17 44004622-44009068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Urea cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 15.4;liver: 47.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 17.5;Proximal enterocytes: 44.8;Proximal tubular cells: 16.8;Spermatocytes: 13.8" "Cancer enhanced" "Detected in all" "liver cancer: 12.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA027300 Supported Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 83: Liver - Metabolism" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "HPA027300: AB_2672207" "unprognostic (1.51e-3)" "unprognostic (9.24e-2)" "unprognostic (1.68e-1)" "unprognostic (8.67e-2)" "unprognostic (1.44e-2)" "unprognostic (1.30e-3)" "unprognostic (2.38e-2)" "unprognostic (1.98e-1)" "unprognostic (3.14e-2)" "unprognostic (2.73e-2)" "unprognostic (2.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.19e-2)" "unprognostic (6.99e-2)" "unprognostic (1.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" NAMPT "PBEF, PBEF1" ENSG00000105835 "Nicotinamide phosphoribosyltransferase" P43490 7 106248298-106285966 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Biological rhythms, Pyridine nucleotide biosynthesis" "Cytokine, Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 2610.8;Macrophages: 1807.9;monocytes: 6490.5;Serous glandular cells: 1795.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 281.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 281.8" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034349, HPA047776, HPA057722" Approved Approved "Nuclear speckles,Cell Junctions" "Secreted to blood" Cytokine NA NA 2140000 1400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 3 "Nuclear speckles" "Cell Junctions" "CAB034349: AB_2251220, HPA047776: AB_2680151, HPA057722: " "unprognostic (2.87e-1)" "prognostic unfavorable (4.78e-4)" "unprognostic (5.90e-3)" "unprognostic (1.63e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (8.81e-4)" "unprognostic (2.15e-1)" "unprognostic (2.74e-2)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (3.02e-1)" "prognostic unfavorable (2.49e-6)" "unprognostic (6.83e-2)" "unprognostic (6.96e-2)" "unprognostic (7.76e-2)" "unprognostic (6.44e-3)" NAPSA "KAP, Kdap, NAP1, NAPA" ENSG00000131400 "Napsin A aspartic peptidase" O96009 19 50358472-50365830 "Enzymes, Plasma proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "lung: 1011.1" "Group enriched" "Detected in many" 11 "Alveolar cells type 1: 1756.1;Alveolar cells type 2: 4693.6" "Cancer enriched" "Detected in many" 18 "lung cancer: 249.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 2.8;plasmacytoid DC: 4.9" "Group enriched" "Detected in many" 9 "B-cells: 2.8;dendritic cells: 4.9" "Cancer enhanced" "Detected in some" "lung cancer: 13.4;lymphoma: 19.4;ovarian cancer: 32.3" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB009591, HPA045280, HPA047236, HPA047744" Enhanced "Secreted in other tissues" Enzyme NA NA 1500000 "Cluster 13: Non-specific - Mitochondria" "Cluster 57: Lung - Lung function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" 2 "CAB009591: , HPA045280: AB_2679283, HPA047236: AB_2679993, HPA047744: AB_2680143" "unprognostic (5.36e-2)" "unprognostic (4.77e-2)" "unprognostic (1.64e-3)" "unprognostic (1.78e-1)" "unprognostic (1.93e-1)" "unprognostic (4.65e-2)" "unprognostic (1.02e-1)" "unprognostic (8.30e-3)" "unprognostic (2.29e-1)" "unprognostic (2.23e-2)" "unprognostic (1.76e-3)" "unprognostic (7.67e-3)" "prognostic favorable (1.21e-4)" "unprognostic (4.08e-4)" "unprognostic (3.29e-1)" "unprognostic (9.83e-3)" "unprognostic (7.26e-5)" NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591756-156609507 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" Transport NA NA 3300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 15: Non-specific - Mixed function" Nucleoplasm "Vesicles, Cytosol" "HPA043766: AB_2678660, HPA048164: AB_2680294" "unprognostic (1.27e-1)" "unprognostic (2.34e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.38e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-3)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.08e-3)" "unprognostic (3.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.15e-2)" "unprognostic (8.05e-2)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 654.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 342.1;Leydig cells: 405.4;Ovarian stromal cells: 526.2;Peritubular cells: 374.8;Proximal enterocytes: 407.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Vascular Endothelial cells, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" "No annotated function" NA NA 8100000 "Cluster 11: T-cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 6: Ovarian stromal cells - Transcription" 2 "CAB026132: , HPA007394: AB_10601272" "unprognostic (1.65e-1)" "unprognostic (1.65e-2)" "unprognostic (9.03e-2)" "unprognostic (2.85e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "unprognostic (7.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.92e-2)" "unprognostic (1.39e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.21e-2)" "unprognostic (2.26e-2)" NCAM1 "CD56, NCAM" ENSG00000149294 "Neural cell adhesion molecule 1" P13591 11 112961247-113278436 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 193.9;heart muscle: 140.8" "Cell type enhanced" "Detected in many" "Astrocytes: 503.5;Excitatory neurons: 445.6;Inhibitory neurons: 421.9;Oligodendrocyte precursor cells: 881.1;Oligodendrocytes: 943.3;Schwann cells: 249.7" "Cancer enriched" "Detected in many" 8 "glioma: 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "NK-cell: 53.9" "Lineage enriched" "Detected in many" 15 "NK-cells: 53.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 126.4" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000142, CAB018071, HPA039835" Enhanced Enhanced "Plasma membrane,Cytosol" "Secreted in other tissues" Receptor NA NA 1200000 2300000000 "Cluster 15: NK-cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 2 "Plasma membrane" Cytosol "CAB000142: , CAB018071: AB_627129, HPA039835: AB_2676705" "unprognostic (7.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.77e-2)" "unprognostic (2.18e-2)" "unprognostic (2.91e-1)" "unprognostic (1.74e-3)" "unprognostic (2.82e-1)" "unprognostic (4.42e-3)" "unprognostic (2.13e-1)" "unprognostic (1.63e-2)" "prognostic favorable (9.11e-6)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.75e-2)" "unprognostic (5.82e-5)" NCAN CSPG3 ENSG00000130287 Neurocan O14594 19 19211958-19252233 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 86 "brain: 102.1" "Cell type enriched" "Detected in some" 6 "Astrocytes: 185.5" "Cancer enriched" "Detected in some" 57 "glioma: 71.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "breast cancer: 2.7;Neuroblastoma: 8.2" "Colon - Colon enteroendocrine cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036814 Enhanced "Secreted in brain" "Cell adhesion" NA NA 790000 "Cluster 61: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 47: Astrocytes - Unknown function" "HPA036814: AB_10673666" "unprognostic (1.02e-2)" "unprognostic (2.84e-3)" "unprognostic (1.92e-1)" "unprognostic (1.56e-2)" "unprognostic (2.35e-2)" "unprognostic (1.65e-2)" "unprognostic (1.70e-2)" "unprognostic (1.03e-3)" "unprognostic (1.76e-1)" "unprognostic (2.12e-1)" "unprognostic (4.58e-3)" "unprognostic (4.38e-2)" "unprognostic (9.09e-6)" "unprognostic (1.10e-2)" "unprognostic (2.79e-2)" "unprognostic (2.91e-1)" "unprognostic (2.58e-2)" NCEH1 "AADACL1, KIAA1363, NCEH" ENSG00000144959 "Neutral cholesterol ester hydrolase 1" Q6PIU2 3 172630249-172711218 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026888, HPA043873" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Macrophages - Innate immune response" "Endoplasmic reticulum" "HPA026888: AB_10601557, HPA043873: " "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (5.74e-2)" "unprognostic (1.27e-1)" "unprognostic (6.88e-3)" "unprognostic (5.41e-2)" "unprognostic (3.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (5.29e-2)" "unprognostic (2.96e-2)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (2.81e-2)" "unprognostic (2.28e-1)" NDFIP1 "MGC10924, N4WBP5" ENSG00000131507 "Nedd4 family interacting protein 1" Q9BT67 5 142108779-142154440 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009682 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "HPA009682: AB_1079455" "unprognostic (2.78e-2)" "unprognostic (1.62e-1)" "unprognostic (9.26e-2)" "unprognostic (5.66e-3)" "unprognostic (4.74e-2)" "prognostic unfavorable (2.33e-7)" "unprognostic (6.95e-2)" "unprognostic (4.96e-2)" "unprognostic (5.97e-2)" "unprognostic (1.74e-2)" "unprognostic (3.28e-1)" "unprognostic (4.46e-2)" "prognostic favorable (2.39e-7)" "unprognostic (9.18e-2)" "unprognostic (2.06e-1)" "unprognostic (6.23e-2)" "unprognostic (8.76e-2)" NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 103.2;placenta: 58.1;retina: 55.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 72.3;Alveolar cells type 2: 44.9;Bipolar cells: 63.3;Early spermatids: 169.7;Late spermatids: 262.5" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 15.6" "Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular Endothelial cells, Lung - Alveolar cells type 1, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" Other NA NA "Cluster 57: Lung - Lung function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 20: Myeloma - Immune response" "Cluster 11: Late spermatids - Unknown function" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" NDP "EVR2, norrin" ENSG00000124479 "Norrin cystine knot growth factor NDP" Q00604 X 43948776-43973395 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision, Wnt signaling pathway" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.8;ovary: 32.8" "Cell type enhanced" "Detected in some" "Astrocytes: 27.6;Granulosa cells: 78.9;Muller glia cells: 105.8;Ovarian stromal cells: 55.4" "Cancer enriched" "Detected in many" 5 "glioma: 25.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Brain cancer: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003095 Supported Nucleoplasm,Nucleoli,Vesicles "Secreted to extracellular matrix" Other NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Ovarian stromal cells - Transcription" 1 Vesicles "Nucleoplasm, Nucleoli" "HPA003095: AB_1079457" "unprognostic (1.12e-1)" "unprognostic (7.12e-2)" "unprognostic (2.27e-2)" "unprognostic (2.55e-3)" "unprognostic (6.84e-3)" "unprognostic (1.51e-1)" "unprognostic (9.09e-2)" "unprognostic (2.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" NDUFA10 CI-42k ENSG00000130414 "NADH:ubiquinone oxidoreductase subunit A10" O95299 2 239892450-240025743 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 318.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 418.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059529, HPA067045, CAB070846" Approved Supported Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "CAB070846: AB_11152346, HPA059529: AB_2684051, HPA067045: AB_2732756" "unprognostic (2.12e-2)" "unprognostic (8.94e-3)" "unprognostic (8.73e-2)" "unprognostic (2.02e-2)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (5.71e-2)" "unprognostic (2.47e-2)" "unprognostic (1.05e-1)" "prognostic favorable (2.09e-7)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.98e-1)" "unprognostic (2.95e-1)" NDUFB11 "ESSS, Np15, NP17.3" ENSG00000147123 "NADH:ubiquinone oxidoreductase subunit B11" Q9NX14 X 47142071-47145466 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 681.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030367 Supported Approved Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 9 Mitochondria "HPA030367: AB_10603882" "unprognostic (2.20e-1)" "unprognostic (6.77e-3)" "unprognostic (1.39e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (8.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.05e-1)" "unprognostic (5.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (3.27e-1)" "unprognostic (2.34e-1)" "unprognostic (1.69e-1)" "unprognostic (8.46e-3)" NDUFB5 "CI-SGDH, MGC12314, SGDH" ENSG00000136521 "NADH:ubiquinone oxidoreductase subunit B5" O43674 3 179604690-179627647 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 500.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005640 Enhanced Supported Nucleoplasm,Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria Nucleoplasm "HPA005640: AB_1079461" "unprognostic (6.76e-2)" "unprognostic (1.09e-2)" "unprognostic (6.33e-2)" "unprognostic (3.51e-3)" "unprognostic (1.38e-1)" "unprognostic (7.35e-3)" "unprognostic (1.33e-2)" "unprognostic (1.63e-1)" "unprognostic (4.46e-2)" "unprognostic (5.96e-3)" "unprognostic (4.83e-2)" "unprognostic (7.11e-2)" "prognostic favorable (3.32e-5)" "unprognostic (3.05e-1)" "unprognostic (1.36e-1)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" NDUFS8 "CI-23k, TYKY" ENSG00000110717 "NADH:ubiquinone oxidoreductase core subunit S8" O00217 11 68030617-68036644 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 753.0;Late spermatids: 785.1;Proximal tubular cells: 890.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018524, HPA067429" Enhanced Approved Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA018524: AB_1854355, HPA067429: " "unprognostic (2.90e-1)" "unprognostic (1.41e-3)" "unprognostic (2.41e-1)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-1)" "unprognostic (7.75e-2)" "unprognostic (3.15e-1)" "unprognostic (1.77e-2)" "unprognostic (3.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (3.27e-8)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (2.60e-2)" "unprognostic (9.45e-2)" NECAB3 "APBA2BP, dJ63M2.4, dJ63M2.5, EFCBP3, NIP1, SYTIP2, XB51" ENSG00000125967 "N-terminal EF-hand calcium binding protein 3" Q96P71 20 33657087-33674463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044785, HPA070595, HPA071786" Supported Supported "Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 21: Early spermatids - Spermatogenesis" 1 "Golgi apparatus" "HPA044785: AB_2679086, HPA070595: AB_2732158, HPA071786: AB_2732186" "unprognostic (8.95e-2)" "unprognostic (1.45e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.44e-1)" "unprognostic (4.05e-2)" "unprognostic (1.17e-1)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.19e-5)" "unprognostic (3.13e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (6.13e-2)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-1)" NECTIN1 "CD111, CLPED1, ED4, HIgR, HVEC, Nectin-1, OFC7, PRR, PRR1, PVRL1, PVRR1, SK-12" ENSG00000110400 "Nectin cell adhesion molecule 1" Q15223 11 119623408-119729200 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 125.1;skin 1: 130.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 89.1;Basal squamous epithelial cells: 60.5;Squamous epithelial cells: 109.7;Suprabasal keratinocytes: 153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 131.1" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016135, HPA026846" Approved "Secreted in other tissues" Receptor NA NA 180000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 4 "CAB016135: AB_626865, HPA026846: AB_1846226" "unprognostic (1.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.11e-1)" "unprognostic (3.87e-2)" "unprognostic (1.26e-1)" "unprognostic (3.20e-2)" "unprognostic (2.25e-3)" "unprognostic (2.03e-1)" "unprognostic (3.76e-2)" "unprognostic (3.42e-1)" "unprognostic (3.58e-2)" "unprognostic (3.28e-1)" "unprognostic (3.59e-3)" "unprognostic (2.13e-2)" "unprognostic (1.91e-1)" "unprognostic (2.46e-1)" "unprognostic (9.62e-2)" NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 96.1;skin 1: 110.2;vagina: 55.6" "Cell type enhanced" "Detected in many" "Club cells: 82.3;Ionocytes: 89.5;Squamous epithelial cells: 110.0;Suprabasal keratinocytes: 183.6;Syncytiotrophoblasts: 462.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 27.9" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" Receptor No No 170000 "Cluster 22: Eosinophils - Transcription" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 2 "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" NELL1 "FLJ45906, IDH3GL" ENSG00000165973 "Neural EGFL like 1" Q92832 11 20669551-21575686 "Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.2;kidney: 16.1" "Group enriched" "Detected in some" 8 "Excitatory neurons: 269.0;Inhibitory neurons: 168.0;Oligodendrocyte precursor cells: 303.3" "Cancer enhanced" "Detected in many" "melanoma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 7.7;Neuroblastoma: 9.8;Rhabdoid: 8.7;skin cancer: 8.1" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051535 Approved "Secreted in other tissues" Other NA NA 160000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA051535: AB_2681524" "unprognostic (1.73e-1)" "unprognostic (1.31e-1)" "unprognostic (7.29e-2)" "unprognostic (5.35e-4)" "unprognostic (3.78e-4)" "unprognostic (1.67e-2)" "unprognostic (3.91e-1)" "unprognostic (4.38e-2)" "unprognostic (4.65e-2)" "unprognostic (1.57e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (7.27e-3)" "unprognostic (4.23e-2)" "unprognostic (1.83e-1)" "unprognostic (2.29e-1)" NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 121.3;choroid plexus: 123.3;retina: 82.6" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 629.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 33.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.6;naive CD8 T-cell: 111.4" "Lineage enriched" "Detected in many" 10 "T-cells: 111.4" "Group enriched" "Detected in many" 5 "Bone cancer: 132.3;Neuroblastoma: 58.4" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" "No annotated function" NA NA 6400000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 3 Vesicles "HPA035714: AB_2674746, HPA035715: AB_10669602" "unprognostic (4.25e-3)" "unprognostic (4.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (7.18e-2)" "unprognostic (5.85e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (1.71e-5)" "unprognostic (8.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.75e-2)" NENF "CIR2, SCIRP10, SPUF" ENSG00000117691 "Neudesin neurotrophic factor" Q9UMX5 1 212432920-212446379 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026763, HPA028488" Uncertain "Secreted to blood" "No annotated function" NA NA 4000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 33: Non-specific - DNA binding" "HPA026763: AB_1854379, HPA028488: AB_2672638" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (2.49e-2)" "unprognostic (7.24e-2)" "unprognostic (7.41e-3)" "unprognostic (3.80e-3)" "unprognostic (5.35e-2)" "unprognostic (1.70e-2)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (4.99e-3)" "prognostic unfavorable (1.54e-6)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (4.28e-1)" "unprognostic (2.28e-2)" NETO1 "BCTL1, BTCL1" ENSG00000166342 "Neuropilin and tolloid like 1" Q8TDF5 18 72742314-72868146 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 26.3;retina: 33.5" "Group enriched" "Detected in some" 14 "Bipolar cells: 216.9;Excitatory neurons: 296.6;Inhibitory neurons: 330.7;Oligodendrocyte precursor cells: 161.8" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "prostate cancer: 64.5" "Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064630 Approved "Golgi apparatus" "Secreted in brain" Receptor NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" "Golgi apparatus" "HPA064630: AB_2685305" "unprognostic (4.02e-2)" "unprognostic (4.08e-3)" "unprognostic (2.75e-1)" "unprognostic (1.55e-2)" "unprognostic (6.04e-2)" "unprognostic (1.35e-5)" "unprognostic (4.05e-1)" "unprognostic (4.73e-2)" "unprognostic (3.09e-1)" "unprognostic (1.56e-1)" "unprognostic (6.63e-2)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (3.70e-2)" "unprognostic (3.35e-2)" "unprognostic (1.59e-1)" "unprognostic (9.13e-3)" NFE2L1 "FLJ00380, LCR-F1, NRF-1, NRF1, TCF11" ENSG00000082641 "NFE2 like bZIP transcription factor 1" Q14494 17 48048329-48061545 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1311.2;tongue: 824.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 436.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063384, HPA065424" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Transcription NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" 3 Nucleoplasm Cytosol "HPA063384: AB_2684998, HPA065424: AB_2685488" "unprognostic (3.19e-1)" "unprognostic (2.41e-1)" "unprognostic (5.44e-2)" "prognostic favorable (8.20e-5)" "unprognostic (5.25e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (5.20e-2)" "unprognostic (5.58e-2)" "unprognostic (9.30e-2)" "unprognostic (2.61e-1)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "prognostic favorable (5.79e-6)" "unprognostic (2.20e-1)" "unprognostic (4.09e-2)" "unprognostic (6.19e-3)" "unprognostic (2.01e-2)" NFE2L3 Nrf3 ENSG00000050344 "NFE2 like bZIP transcription factor 3" Q9Y4A8 7 26152198-26187137 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 33.3" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 294.9;Syncytiotrophoblasts: 646.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055889 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" Transcription NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 58: Placenta - Pregnancy" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" 3 "Nucleoplasm, Vesicles" "HPA055889: AB_2682958" "unprognostic (4.99e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-3)" "unprognostic (5.37e-2)" "unprognostic (8.41e-2)" "unprognostic (4.00e-3)" "unprognostic (7.29e-3)" "unprognostic (1.87e-1)" "unprognostic (2.12e-1)" "unprognostic (9.88e-2)" "prognostic unfavorable (6.62e-5)" "unprognostic (2.32e-1)" "prognostic unfavorable (7.58e-12)" "prognostic favorable (2.14e-4)" "unprognostic (2.40e-1)" "unprognostic (8.25e-2)" "unprognostic (4.13e-3)" NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 54.5;brain: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.1;Excitatory neurons: 102.4;Proximal enterocytes: 57.7" "Cancer enhanced" "Detected in many" "testis cancer: 22.5" "Group enriched" "Detected in all" 4 "basal ganglia: 380.4;cerebral cortex: 233.6;white matter: 165.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 219.2;cerebral cortex: 173.3;hippocampal formation: 95.4" HPA008160 Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" 8 "Plasma membrane, Cytosol" "HPA008160: AB_1854450" "unprognostic (3.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-3)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-3)" "unprognostic (5.41e-3)" "unprognostic (2.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-1)" NGF NGFB ENSG00000134259 "Nerve growth factor" P01138 1 115285904-115338770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.1;ovary: 18.3" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 15.1;Leydig cells: 28.7;Oligodendrocyte precursor cells: 11.3;Ovarian stromal cells: 13.3;Sertoli cells: 57.1;Smooth muscle cells: 16.3" "Cancer enhanced" "Detected in many" "renal cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 18.9" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" "Growth factor" NA NA 40000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 15: Non-specific - Mixed function" 5 "unprognostic (7.55e-2)" "unprognostic (2.66e-2)" "unprognostic (1.53e-3)" "unprognostic (8.85e-2)" "unprognostic (4.12e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (5.30e-2)" "unprognostic (8.73e-3)" "unprognostic (4.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.08e-7)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (7.99e-3)" "unprognostic (1.62e-4)" NGLY1 "FLJ11005, PNG-1, PNG1" ENSG00000151092 "N-glycanase 1" Q96IV0 3 25718944-25790039 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 437.3;Late spermatids: 1038.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036825 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 11: Late spermatids - Unknown function" 12 "HPA036825: AB_10672231" "unprognostic (3.65e-2)" "unprognostic (8.65e-2)" "prognostic favorable (1.17e-5)" "unprognostic (2.96e-2)" "unprognostic (1.72e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (1.96e-6)" "unprognostic (2.20e-1)" "unprognostic (2.34e-1)" "unprognostic (3.73e-3)" "unprognostic (2.55e-1)" "unprognostic (4.23e-2)" "unprognostic (4.92e-3)" "unprognostic (1.07e-2)" "unprognostic (2.47e-1)" "unprognostic (9.08e-2)" "unprognostic (1.89e-2)" NGRN DSC92 ENSG00000182768 "Neugrin, neurite outgrowth associated" Q9NPE2 15 90265659-90275778 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 363.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 64.7;Excitatory neurons: 56.3;Inhibitory neurons: 51.6;Squamous epithelial cells: 50.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041367, HPA076267" Supported Supported "Nucleoplasm,Cytokinetic bridge,Mitochondria" "Intracellular and membrane" "Developmental protein" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" 2 Mitochondria "Nucleoplasm, Cytokinetic bridge" "HPA041367: AB_10796668, HPA076267: " "unprognostic (2.82e-1)" "unprognostic (1.04e-2)" "unprognostic (1.66e-3)" "unprognostic (2.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.19e-2)" "unprognostic (2.94e-2)" "unprognostic (5.00e-2)" "unprognostic (7.78e-2)" "unprognostic (1.93e-2)" "unprognostic (5.22e-2)" "unprognostic (7.22e-2)" "unprognostic (3.31e-2)" "unprognostic (2.10e-1)" "unprognostic (2.05e-1)" "unprognostic (1.68e-3)" "unprognostic (3.21e-1)" NHLRC3 ENSG00000188811 "NHL repeat containing 3" Q5JS37 13 39038306-39050109 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013738 Uncertain "Secreted to blood" "No annotated function" NA NA 310000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Liver - Plasma proteins" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 19: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" "HPA013738: AB_1854455" "unprognostic (7.92e-2)" "unprognostic (3.51e-2)" "unprognostic (5.96e-2)" "unprognostic (3.90e-1)" "unprognostic (2.92e-2)" "unprognostic (1.22e-1)" "unprognostic (2.99e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-1)" "unprognostic (8.88e-2)" "unprognostic (2.28e-2)" "unprognostic (4.83e-2)" "unprognostic (3.21e-1)" "unprognostic (1.58e-2)" "unprognostic (2.99e-2)" "unprognostic (1.66e-1)" "unprognostic (7.81e-2)" NID1 "entactin, NID" ENSG00000116962 "Nidogen 1" P14543 1 235975830-236065109 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 223.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 347.3;Fibroblasts: 215.3;Leydig cells: 168.8;Peritubular cells: 121.9;Sertoli cells: 103.3;Smooth muscle cells: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 5.7;intermediate monocyte: 11.2;myeloid DC: 4.4;non-classical monocyte: 7.3" "Group enriched" "Detected in many" 17 "dendritic cells: 4.4;monocytes: 11.2" "Cancer enhanced" "Detected in many" "Rhabdoid: 108.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010044, HPA065049" Approved Uncertain "Vesicles,Mitotic spindle" "Secreted to extracellular matrix" "Cell adhesion" Yes NA 150000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" Vesicles "Mitotic spindle" "CAB010044: AB_2153287, HPA065049: " "unprognostic (1.17e-1)" "unprognostic (2.23e-3)" "unprognostic (3.24e-1)" "unprognostic (2.35e-1)" "unprognostic (4.03e-1)" "unprognostic (2.79e-2)" "unprognostic (2.44e-3)" "unprognostic (1.42e-2)" "unprognostic (7.88e-2)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (5.38e-8)" "unprognostic (3.64e-3)" "unprognostic (1.35e-1)" "unprognostic (7.36e-2)" "unprognostic (3.72e-3)" NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004809-52069059 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 59.4;placenta: 58.7" "Cell type enhanced" "Detected in many" "Adipocytes: 25.7;Fibroblasts: 26.9;Lymphatic endothelial cells: 31.5;Mesothelial cells: 23.8;Microglial cells: 18.8;Smooth muscle cells: 20.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Region enriched" "Detected in all" 18 "choroid plexus: 97.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 50.3" "Liver - Hepatic stellate cells, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 6300000 "Cluster 62: Connective tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" "Plasma membrane" "HPA052460: AB_2681840, HPA058772: AB_2683815" "unprognostic (6.51e-2)" "unprognostic (3.55e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-2)" "unprognostic (3.05e-3)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.48e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (4.58e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (2.78e-4)" NINJ1 NIN1 ENSG00000131669 "Ninjurin 1" Q92982 9 93121496-93134251 "Predicted membrane proteins" "Angiogenesis, Cell adhesion, Cytolysis, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 283.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 582.6;Langerhans cells: 846.8;monocytes: 591.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1675.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 1675.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045063 Uncertain "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 16 "HPA045063: AB_10964133" "unprognostic (1.23e-2)" "unprognostic (8.25e-3)" "unprognostic (3.64e-3)" "unprognostic (1.40e-2)" "unprognostic (8.18e-2)" "unprognostic (1.28e-2)" "unprognostic (4.29e-2)" "unprognostic (5.88e-2)" "unprognostic (6.82e-2)" "unprognostic (9.06e-2)" "unprognostic (1.93e-1)" "unprognostic (1.74e-2)" "unprognostic (9.45e-3)" "unprognostic (2.51e-1)" "unprognostic (2.69e-2)" "unprognostic (1.40e-3)" "unprognostic (7.46e-3)" NLGN1 KIAA1070 ENSG00000169760 "Neuroligin 1" Q8N2Q7 3 173396284-174294372 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biological rhythms, Cell adhesion" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3;retina: 10.7" "Group enriched" "Detected in many" 31 "Excitatory neurons: 1433.6;Inhibitory neurons: 1626.3;Oligodendrocyte precursor cells: 3757.2;Oligodendrocytes: 1174.3" "Group enriched" "Detected in some" 9 "glioma: 3.8;melanoma: 2.2;renal cancer: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.1" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006572, HPA006680, CAB033261" Enhanced Uncertain "Nuclear bodies,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 82000 "Cluster 17: Neuronal - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Plasma membrane" "Nuclear bodies" "CAB033261: AB_2151659, HPA006572: , HPA006680: AB_1854400" "unprognostic (2.81e-1)" "unprognostic (9.86e-2)" "unprognostic (3.08e-5)" "unprognostic (7.52e-5)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (6.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.78e-1)" "unprognostic (8.07e-2)" "unprognostic (3.21e-3)" "unprognostic (1.86e-2)" "unprognostic (1.97e-1)" "unprognostic (4.08e-2)" "unprognostic (8.81e-2)" "unprognostic (2.41e-3)" "unprognostic (5.37e-2)" NLGN3 "ASPGX1, AUTSX1, HNL3, KIAA1480" ENSG00000196338 "Neuroligin 3" Q9NZ94 X 71144821-71175255 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.0;seminal vesicle: 11.7" "Cell type enhanced" "Detected in some" "Astrocytes: 18.6;Inhibitory neurons: 12.1;Oligodendrocyte precursor cells: 86.3;Oligodendrocytes: 40.6;Peritubular cells: 16.3;Schwann cells: 17.6" "Cancer enriched" "Detected in many" 19 "glioma: 37.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.5" "Colon - Enteric glia cells, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003183, HPA004066" Enhanced Supported "Golgi apparatus,Cell Junctions" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Golgi apparatus, Cell Junctions" "HPA003183: AB_1079469, HPA004066: AB_2732397" "unprognostic (4.06e-2)" "unprognostic (1.77e-1)" "unprognostic (1.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.42e-1)" "unprognostic (3.87e-1)" "unprognostic (6.52e-2)" "unprognostic (1.63e-1)" "unprognostic (7.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (6.18e-2)" "unprognostic (4.27e-9)" "unprognostic (4.28e-2)" "unprognostic (1.90e-1)" "unprognostic (2.22e-5)" "unprognostic (9.01e-2)" NLGN4Y KIAA0951 ENSG00000165246 "Neuroligin 4 Y-linked" Q8NFZ3 Y 14522573-14845654 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 7.1" "Cell type enhanced" "Detected in many" "Astrocytes: 45.5;Basal squamous epithelial cells: 37.2;Excitatory neurons: 141.1;Inhibitory neurons: 103.3;Oligodendrocyte precursor cells: 207.1;Oligodendrocytes: 43.3" "Cancer enhanced" "Detected in many" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "testis cancer: 18.3" HPA001651 Approved "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 34: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA001651: AB_1079470" "unprognostic (2.31e-1)" "unprognostic (9.19e-2)" "unprognostic (2.84e-5)" "unprognostic (7.85e-2)" "unprognostic (6.46e-2)" "unprognostic (8.80e-3)" "unprognostic (7.71e-2)" "unprognostic (6.26e-2)" "unprognostic (5.89e-2)" "unprognostic (7.20e-3)" "unprognostic (1.88e-1)" "unprognostic (5.65e-2)" NLRP5 "CLR19.8, MATER, NALP5, PAN11, PYPAF8" ENSG00000171487 "NLR family pyrin domain containing 5" P59047 19 55999726-56061810 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 61 "ovary: 6.4;parathyroid gland: 21.7" "Cell type enriched" "Detected in some" 20 "Oocytes: 363.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.3" "Breast - Breast glandular cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047260, HPA056271" Uncertain Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Oocytes - Unknown function" "Golgi apparatus" Vesicles "HPA047260: , HPA056271: AB_2683083" "unprognostic (9.67e-2)" "unprognostic (2.22e-2)" "unprognostic (5.03e-1)" "unprognostic (7.78e-2)" "unprognostic (1.72e-1)" NMB "MGC17211, MGC2277, MGC3936" ENSG00000197696 "Neuromedin B" P08949 15 84655129-84658563 "Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 65.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 330.8;Club cells: 103.0;Ductal cells: 124.7;Ionocytes: 162.4" "Cancer enhanced" "Detected in all" "glioma: 93.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Region enriched" "Detected in all" 16 "olfactory bulb: 168.1" "Group enriched" "Detected in all" 5 "olfactory bulb: 59.4;pons: 19.1" CAB019302 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted to blood" Immunity NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Nucleoplasm, Vesicles" "Plasma membrane" "CAB019302: " "unprognostic (2.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-3)" "unprognostic (3.79e-1)" "prognostic favorable (3.43e-4)" "unprognostic (3.81e-1)" "unprognostic (6.45e-2)" "unprognostic (1.45e-2)" "unprognostic (2.17e-1)" "unprognostic (4.36e-1)" "unprognostic (7.24e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.25e-4)" "unprognostic (7.92e-3)" "unprognostic (1.45e-1)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" NME1 "NDPKA, NM23, NM23-H1" ENSG00000239672 "NME/NM23 nucleoside diphosphate kinase 1" P15531 17 51153559-51162428 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1024.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008467, CAB040571, HPA041113, CAB080149, CAB080151, CAB080152" Supported Supported Cytosol "Intracellular and membrane" Enzyme NA NA 21000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 15 Cytosol "CAB040571: , CAB080149: , CAB080151: , CAB080152: , HPA008467: AB_1079492, HPA041113: AB_2677305" "unprognostic (2.24e-1)" "unprognostic (2.01e-1)" "unprognostic (3.48e-3)" "unprognostic (5.96e-2)" "unprognostic (9.71e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (2.60e-5)" "unprognostic (4.54e-2)" "unprognostic (3.35e-1)" "unprognostic (2.33e-3)" "unprognostic (2.90e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.07e-9)" "unprognostic (9.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.83e-1)" "unprognostic (9.46e-2)" NME3 "DR-nm23, NDPKC, NM23-H3" ENSG00000103024 "NME/NM23 nucleoside diphosphate kinase 3" Q13232 16 1770320-1771561 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041113, HPA052733" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA 12000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 7 Nucleoplasm Cytosol "HPA041113: AB_2677305, HPA052733: AB_2681930" "prognostic favorable (6.81e-5)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-3)" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (4.54e-2)" "unprognostic (1.13e-1)" "unprognostic (6.22e-3)" "unprognostic (4.40e-2)" "unprognostic (4.43e-2)" "unprognostic (7.09e-3)" "unprognostic (1.79e-1)" "unprognostic (3.84e-1)" "unprognostic (3.64e-1)" "unprognostic (6.11e-3)" NMI ENSG00000123609 "N-myc and STAT interactor" Q13287 2 151270470-151289894 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008588 Approved Supported Nucleoplasm,Cytosol "Secreted to blood" Immunity NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 29: Monocytes - Innate immune response" 27 "Nucleoplasm, Cytosol" "HPA008588: AB_1079493" "unprognostic (5.28e-2)" "unprognostic (1.52e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-2)" "unprognostic (9.25e-2)" "unprognostic (3.63e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.42e-2)" "unprognostic (1.08e-1)" "unprognostic (4.51e-3)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.57e-7)" "unprognostic (1.91e-1)" "unprognostic (4.69e-2)" "unprognostic (1.52e-2)" "unprognostic (4.57e-2)" NMS ENSG00000204640 "Neuromedin S" Q5H8A3 2 100470482-100483280 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "medulla oblongata: 5.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basal ganglia: 2.4;hypothalamus: 5.4;pons and medulla: 1.3" "Secreted in brain" Neuropeptide NA NA "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Smooth muscle cells - Signal transduction" NMU ENSG00000109255 "Neuromedin U" P48645 4 55595229-55636698 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 97.4;skin 1: 37.4;vagina: 29.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 89.8;Basal squamous epithelial cells: 48.3;Squamous epithelial cells: 238.8;Suprabasal keratinocytes: 240.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 15.4" "Group enriched" "Detected in some" 10 "MAIT T-cell: 3.6;memory CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 37 "T-cells: 3.6" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Group enriched" "Detected in some" 8 "hypothalamus: 1.1;pons and medulla: 4.5" "Low region specificity" "Detected in some" HPA025926 Uncertain "Secreted in other tissues" Neuropeptide NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 12: Squamous epithelial cells - Keratinization" 14 "HPA025926: AB_1854539" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (5.83e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.08e-1)" "unprognostic (5.19e-2)" "unprognostic (7.12e-2)" "unprognostic (7.29e-3)" "unprognostic (9.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.07e-10)" "unprognostic (1.61e-1)" "unprognostic (5.66e-2)" "unprognostic (2.54e-2)" "unprognostic (5.55e-2)" NOA1 "C4orf14, hAtNOS1, hNOA1, MGC3232, MTG3" ENSG00000084092 "Nitric oxide associated 1" Q8NC60 4 56963350-56977606 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035838, HPA035839" Approved Supported Mitochondria "Intracellular and membrane" Other NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 18: Non-specific - Ribosome" "Cluster 31: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 3 Mitochondria "HPA035838: AB_10669531, HPA035839: AB_10669658" "unprognostic (6.61e-2)" "unprognostic (1.66e-1)" "unprognostic (1.65e-3)" "unprognostic (5.19e-2)" "unprognostic (9.06e-2)" "unprognostic (1.49e-2)" "unprognostic (2.04e-2)" "unprognostic (1.29e-1)" "unprognostic (1.75e-1)" "unprognostic (1.01e-3)" "unprognostic (3.64e-2)" "unprognostic (1.33e-1)" "prognostic favorable (2.38e-4)" "unprognostic (8.97e-2)" "unprognostic (6.87e-2)" "unprognostic (1.79e-2)" "unprognostic (4.27e-2)" NODAL ENSG00000156574 "Nodal growth differentiation factor" Q96S42 10 70431936-70447951 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Developmental protein, Growth factor" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 2.2;testis: 1.8" "Cell type enriched" "Detected in some" 5 "Late spermatids: 39.9" "Cancer enriched" "Detected in some" 10 "testis cancer: 20.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 3.2" "Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.0" HPA045201 Uncertain "Secreted to blood" Cytokine NA NA "Cluster 72: Testis & Skeletal muscle - Protein ubiquitination" "Cluster 15: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 36: Late spermatids - Unknown function" 1 "HPA045201: AB_2679252" "unprognostic (3.07e-2)" "unprognostic (2.10e-1)" "unprognostic (1.51e-2)" "unprognostic (2.41e-1)" "unprognostic (1.70e-1)" "unprognostic (4.57e-2)" "unprognostic (1.50e-1)" "unprognostic (1.65e-1)" "unprognostic (5.66e-3)" "unprognostic (3.12e-2)" "unprognostic (8.77e-2)" "unprognostic (1.61e-1)" "unprognostic (1.63e-5)" "unprognostic (4.37e-1)" "unprognostic (6.98e-2)" "unprognostic (1.19e-1)" "unprognostic (2.02e-1)" NOG "SYM1, SYNS1" ENSG00000183691 Noggin Q13253 17 56593699-56595611 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;placenta: 10.3" "Cell type enriched" "Detected in some" 6 "Extravillous trophoblasts: 15.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 73.0;naive CD8 T-cell: 35.0" "Lineage enriched" "Detected in single" 78 "T-cells: 73.0" "Cancer enhanced" "Detected in many" "Rhabdoid: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061318 Approved "Secreted to blood" "Developmental protein" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 19: NK-cells - Adaptive immune response" "HPA061318: AB_2684478" "unprognostic (1.49e-1)" "unprognostic (1.17e-2)" "unprognostic (1.49e-5)" "prognostic favorable (6.66e-4)" "unprognostic (4.69e-2)" "unprognostic (5.23e-3)" "unprognostic (1.26e-2)" "unprognostic (3.06e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (6.86e-5)" "unprognostic (2.88e-1)" "unprognostic (1.14e-6)" "unprognostic (8.39e-2)" "unprognostic (1.40e-1)" "unprognostic (5.00e-1)" "unprognostic (1.65e-1)" NOTCH2NLA "N2N, NOTCH2NL" ENSG00000264343 "Notch 2 N-terminal like A" Q7Z3S9 1 146146203-146229041 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 33.9;monocytes: 28.4;Paneth cells: 23.4;Squamous epithelial cells: 47.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 40.4;classical monocyte: 46.9;eosinophil: 90.4;intermediate monocyte: 40.9;memory B-cell: 76.3;myeloid DC: 61.1;naive B-cell: 44.2;neutrophil: 42.9;non-classical monocyte: 42.1;plasmacytoid DC: 49.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" CAB004669 Uncertain "Secreted to blood" "Developmental protein" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 12: Non-specific - Vasculature" "Cluster 45: Non-specific - Nuclear processes" "Cluster 49: Non-specific - Transcription" 190 "CAB004669: AB_426149" "unprognostic (1.54e-1)" "unprognostic (8.28e-3)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (2.75e-1)" "unprognostic (2.09e-1)" "unprognostic (1.35e-2)" "unprognostic (3.40e-2)" "unprognostic (1.56e-1)" "unprognostic (4.28e-4)" "unprognostic (1.26e-2)" "unprognostic (1.81e-1)" "unprognostic (8.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.91e-1)" "unprognostic (7.59e-2)" "unprognostic (1.83e-2)" NOTCH2NLB ENSG00000286019 "Notch 2 N-terminal like B" P0DPK3 1 148600285-148679746 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Notch signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 74.0;Microglial cells: 17.0;Oligodendrocyte precursor cells: 34.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Secreted to blood" Other NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 45: Non-specific - Nuclear processes" "Cluster 47: Astrocytes - Unknown function" NOTCH2NLC ENSG00000286219 "Notch 2 N-terminal like C" P0DPK4 1 149390621-149471833 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Notch signaling pathway" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 18.9;Paneth cells: 16.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Secreted to blood" Other NA NA "Cluster 41: Basophils - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Monocytes - Innate immune response" 178 NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "placenta: 131.0" "Cell type enriched" "Detected in some" 92 "Extravillous trophoblasts: 1216.7" "Cancer enhanced" "Detected in many" "stomach cancer: 48.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 49.8" "Breast - Breast glandular cells (progenitors), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" Enzyme NA NA 1900000 "Cluster 58: Placenta - Pregnancy" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "Endoplasmic reticulum" "HPA022851: " "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-2)" "unprognostic (4.80e-3)" "unprognostic (1.97e-1)" "unprognostic (9.02e-3)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (6.49e-2)" "unprognostic (8.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (4.48e-6)" "unprognostic (1.76e-1)" "unprognostic (9.88e-2)" "unprognostic (1.22e-3)" "unprognostic (1.00e-1)" NPB "PPL7, PPNPB" ENSG00000183979 "Neuropeptide B" Q8NG41 17 81900745-81902905 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 10.9" "Group enriched" "Detected in many" 7 "Spermatogonia: 44.5;Syncytiotrophoblasts: 132.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" Neuropeptide NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "unprognostic (2.44e-2)" "unprognostic (6.21e-2)" "unprognostic (2.90e-1)" "unprognostic (3.47e-3)" "unprognostic (9.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.31e-1)" "unprognostic (1.92e-1)" "unprognostic (3.55e-2)" "unprognostic (5.40e-2)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-2)" "unprognostic (3.71e-1)" "unprognostic (4.32e-1)" NPC2 "EDDM1, HE1, NP-C2" ENSG00000119655 "NPC intracellular cholesterol transporter 2" P61916 14 74476192-74494177 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "epididymis: 16376.6" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2445.0;Hofbauer cells: 3032.8;Kupffer cells: 1533.7" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 769.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 671.5;classical monocyte: 1304.7;intermediate monocyte: 1776.9;myeloid DC: 588.8;neutrophil: 678.2;non-classical monocyte: 1258.0;plasmacytoid DC: 2119.0" "Group enriched" "Detected in all" 5 "dendritic cells: 2119.0;granulocytes: 678.2;monocytes: 1776.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000835, CAB032888" Enhanced "Secreted to blood" Transport NA NA 53000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 2 "CAB032888: AB_2157036, HPA000835: AB_1079499" "unprognostic (1.27e-3)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.83e-5)" "unprognostic (1.17e-1)" "unprognostic (1.82e-2)" "unprognostic (3.72e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (6.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.32e-1)" "unprognostic (3.11e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.97e-1)" "prognostic favorable (6.55e-4)" "unprognostic (1.42e-1)" NPFF FMRFAL ENSG00000139574 "Neuropeptide FF-amide peptide precursor" O15130 12 53506688-53507484 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 596 "epididymis: 1540.2" "Cell type enhanced" "Detected in some" "Astrocytes: 10.5;Excitatory neurons: 1.3;Inhibitory neurons: 1.1;Microglial cells: 1.8;Oligodendrocytes: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Rhabdoid: 4.3" "Region enriched" "Detected in some" 7 "pons and medulla: 11.4" "Region enriched" "Detected in all" 6 "cerebellum: 30.3" "Secreted in male reproductive system" Neuropeptide NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 43: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 47: Astrocytes - Unknown function" NPIPB15 "LOC440348, NPIPL2" ENSG00000196436 "Nuclear pore complex interacting protein family member B15" A6NHN6 16 74376306-74392115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 54.4" "Group enriched" "Detected in many" 4 "Early spermatids: 286.0;Late spermatids: 222.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA011188, HPA053611" Supported Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 78: Testis - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm "HPA011188: AB_2668455, HPA053611: AB_2682206" "unprognostic (2.23e-2)" "unprognostic (3.48e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-1)" "unprognostic (9.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.56e-2)" "unprognostic (5.53e-2)" "unprognostic (2.41e-2)" "unprognostic (7.73e-2)" "unprognostic (4.58e-3)" "unprognostic (1.53e-1)" "unprognostic (2.81e-2)" "unprognostic (1.97e-1)" "unprognostic (7.34e-3)" "unprognostic (2.53e-1)" "unprognostic (1.14e-3)" NPIPB7 "LOC440350, NPIPL1" ENSG00000233232 "Nuclear pore complex interacting protein family member B7" O75200 16 28456329-28472336 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 20.4" "Group enriched" "Detected in some" 25 "Early spermatids: 34.1;Late spermatids: 63.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "HPA011188, HPA053611" Approved Approved Nucleoplasm "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 21: Testis - Unknown function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 13: Spermatids - Transcription" Nucleoplasm "HPA011188: AB_2668455, HPA053611: AB_2682206" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" "unprognostic (8.35e-2)" "unprognostic (1.94e-1)" "unprognostic (1.94e-1)" "unprognostic (7.43e-2)" "unprognostic (3.07e-3)" "unprognostic (3.35e-2)" "unprognostic (3.44e-1)" "unprognostic (2.78e-2)" "unprognostic (3.62e-2)" "unprognostic (3.04e-2)" "unprognostic (4.40e-1)" "unprognostic (2.22e-1)" "unprognostic (7.73e-2)" "unprognostic (2.03e-2)" NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 132.8;thyroid gland: 227.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 166.3;Alveolar cells type 2: 94.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Region enhanced" "Detected in all" "midbrain: 63.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 71.1" "Adipose subcutaneous - Smooth muscle cells, Kidney - Podocytes, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" "Developmental protein" NA NA 120000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 72: Alveolar cells - Lung function" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" NPPA "ANP, PND" ENSG00000175206 "Natriuretic peptide A" P01160 1 11845709-11848345 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hormone, Vasoactive, Vasodilator" "Atrial fibrillation, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 872 "heart muscle: 58077.5" "Cell type enriched" "Detected in some" 42 "Cardiomyocytes: 18510.2" "Cancer enriched" "Detected in some" 9 "glioma: 7.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "lung cancer: 7.5" "Region enriched" "Detected in some" 7 "olfactory bulb: 22.8" "Low region specificity" "Detected in all" "HPA058269, HPA064007" Enhanced "Secreted to blood" Hormone NA NA 1200000 "Cluster 30: Heart muscle - Heart development" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 68: Cardiomyocytes - Muscle contraction" 4 "HPA058269: AB_2683660, HPA064007: " "unprognostic (1.27e-3)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (1.48e-1)" "unprognostic (3.25e-2)" "unprognostic (9.72e-3)" "unprognostic (2.21e-1)" "unprognostic (5.93e-4)" "unprognostic (2.31e-1)" "unprognostic (1.59e-1)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" NPPB ENSG00000120937 "Natriuretic peptide B" P16860 1 11857464-11858945 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Hormone, Vasoactive, Vasodilator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 556 "heart muscle: 4968.9" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 360.4;Pancreatic endocrine cells: 331.1;Sertoli cells: 291.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.2" "Region enriched" "Detected in some" 7 "basal ganglia: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 79.4;testis cancer: 62.4" "Region enhanced" "Detected in single" "pons and medulla: 1.4" "Low region specificity" "Detected in all" HPA077324 Approved Vesicles,Cytosol "Secreted to blood" Hormone NA NA 9680 "Cluster 30: Heart muscle - Heart development" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 7 Vesicles Cytosol "HPA077324: " "unprognostic (3.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.49e-1)" "unprognostic (4.23e-1)" "unprognostic (3.28e-2)" NPPC CNP ENSG00000163273 "Natriuretic peptide C" P23582 2 231921809-231926396 "Predicted secreted proteins, Transporters" Osteogenesis "Hormone, Vasoactive" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 86.9;Breast myoepithelial cells: 20.5;Cone photoreceptor cells: 30.6;Fibroblasts: 20.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "medulla oblongata: 75.9;spinal cord: 72.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 9.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "medulla oblongata: 20.2;spinal cord: 16.4" HPA035362 Uncertain "Secreted to blood" Hormone NA NA 6140 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "HPA035362: AB_10671103" "unprognostic (9.70e-2)" "unprognostic (4.45e-2)" "unprognostic (1.99e-1)" "unprognostic (1.06e-2)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.83e-1)" "unprognostic (3.22e-3)" "unprognostic (9.81e-3)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" "unprognostic (4.06e-2)" "unprognostic (1.17e-1)" "unprognostic (6.58e-2)" "unprognostic (1.18e-1)" "unprognostic (3.72e-1)" "unprognostic (1.91e-1)" NPS ENSG00000214285 "Neuropeptide S" P0C0P6 10 127549309-127553540 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "head and neck cancer: 4.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "midbrain: 5.4;pons and medulla: 5.1" "Group enriched" "Detected in some" 9 "cerebral cortex: 2.1;white matter: 1.2" CAB020139 Uncertain "Secreted in brain" Neuropeptide NA NA "Cluster 1: Neuronal - Visual perception" "CAB020139: AB_776718" "unprognostic (2.83e-1)" NPTX1 ENSG00000171246 "Neuronal pentraxin 1" Q15818 17 80466834-80477843 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 188.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 236.2;Excitatory neurons: 85.5;Horizontal cells: 34.0;Late spermatids: 43.9" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 32.8" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 74.9;cerebellum: 175.3;cerebral cortex: 136.6;hippocampal formation: 175.7" HPA077062 Enhanced Approved Approved "Golgi apparatus,Vesicles" "Secreted in brain" "No annotated function" NA NA 1100000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "Golgi apparatus" Vesicles "HPA077062: AB_2732329" "unprognostic (2.37e-2)" "unprognostic (1.18e-1)" "unprognostic (1.81e-2)" "unprognostic (6.95e-2)" "unprognostic (4.16e-3)" "unprognostic (2.43e-2)" "unprognostic (1.48e-2)" "unprognostic (3.63e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-1)" "unprognostic (1.81e-2)" "unprognostic (9.63e-3)" "unprognostic (1.05e-6)" "unprognostic (1.41e-4)" "unprognostic (1.35e-1)" "unprognostic (8.86e-6)" "unprognostic (2.71e-3)" NPTX2 ENSG00000106236 "Neuronal pentraxin 2" P47972 7 98617285-98629869 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pituitary gland: 205.1" "Cell type enhanced" "Detected in many" "Peritubular cells: 315.8;Schwann cells: 98.0;Sertoli cells: 89.8;Spermatocytes: 114.4;Spermatogonia: 52.3" "Cancer enhanced" "Detected in all" "renal cancer: 41.7" "Region enhanced" "Detected in all" "cerebral cortex: 280.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 82.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB020801, HPA049799, HPA058320" Enhanced Approved "Golgi apparatus,Actin filaments,Centrosome" "Secreted to blood" "No annotated function" NA NA 2490000 360000 "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 1 "Golgi apparatus, Actin filaments" Centrosome "CAB020801: , HPA049799: AB_2680889, HPA058320: AB_2732621" "unprognostic (1.18e-1)" "unprognostic (9.61e-2)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (1.91e-3)" "unprognostic (9.20e-2)" "unprognostic (2.42e-2)" "unprognostic (6.04e-3)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (7.64e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (5.46e-9)" "unprognostic (1.06e-2)" "unprognostic (1.21e-1)" "unprognostic (5.33e-2)" "unprognostic (3.69e-2)" NPTXR ENSG00000221890 "Neuronal pentraxin receptor" O95502 22 38818452-38844028 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 179.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.5;Excitatory neurons: 40.3;Inhibitory neurons: 48.1;Oligodendrocyte precursor cells: 17.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 42.6" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001079 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 420000 "Cluster 61: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA001079: AB_1078414" "unprognostic (6.29e-2)" "prognostic favorable (3.93e-4)" "unprognostic (6.82e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.55e-2)" "unprognostic (6.93e-2)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-2)" "unprognostic (1.71e-1)" "unprognostic (1.52e-3)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.49e-2)" "unprognostic (9.22e-2)" "unprognostic (8.65e-2)" "unprognostic (2.77e-2)" NPVF "C7orf9, RFRP" ENSG00000105954 "Neuropeptide VF precursor" Q9HCQ7 7 25224570-25228486 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "retina: 213.7" "Cell type enriched" "Detected in some" 78 "Muller glia cells: 469.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 15 "hypothalamus: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 18 "hypothalamus: 6.1" "Region enriched" "Detected in single" 8 "hypothalamus: 3.9" HPA041733 Enhanced "Secreted in other tissues" Neuropeptide NA NA "Cluster 76: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 65: Non-specific - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 2 "HPA041733: AB_10794524" NPW PPL8 ENSG00000183971 "Neuropeptide W" Q8N729 16 2009926-2020755 "Predicted intracellular proteins, Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 10.3" "Group enriched" "Detected in many" 5 "Endometrial stromal cells: 210.0;Enteroendocrine cells: 370.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Bone cancer: 43.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA064874 Approved "Secreted to blood" Neuropeptide NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA064874: AB_2685378" "unprognostic (7.54e-2)" "unprognostic (4.45e-3)" "unprognostic (3.20e-1)" "unprognostic (4.31e-3)" "unprognostic (8.85e-2)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-1)" "unprognostic (3.06e-1)" "unprognostic (2.20e-2)" "unprognostic (6.26e-3)" "unprognostic (2.37e-1)" "unprognostic (1.81e-5)" "unprognostic (6.53e-3)" "unprognostic (1.26e-1)" "unprognostic (4.41e-1)" "unprognostic (3.43e-2)" NPY PYY4 ENSG00000122585 "Neuropeptide Y" P01303 7 24284188-24291862 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Neuropeptide "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "adrenal gland: 118.5;brain: 285.3;prostate: 321.4" "Cell type enriched" "Detected in some" 14 "Prostatic glandular cells: 1630.9" "Cancer enriched" "Detected in many" 187 "prostate cancer: 1214.9" "Region enriched" "Detected in many" 9 "hypothalamus: 885.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 15 "Neuroblastoma: 353.3;prostate cancer: 285.9" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016733, CAB034368, HPA036636, HPA044572, HPA056798" Supported Supported Supported "Golgi apparatus" "Secreted to blood" Neuropeptide NA NA 30700000 21000 "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Prostatic glandular cells - Transcription" 1 "Golgi apparatus" "CAB016733: , CAB034368: AB_2298657, HPA036636: , HPA044572: AB_2678996, HPA056798: AB_2630371" "unprognostic (2.00e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (4.15e-1)" "unprognostic (3.76e-2)" "unprognostic (1.59e-2)" "unprognostic (1.87e-1)" "unprognostic (6.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.78e-1)" "unprognostic (2.52e-1)" NRCAM "Bravo, KIAA0343" ENSG00000091129 "Neuronal cell adhesion molecule" Q92823 7 108147623-108456717 "Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.3" "Group enriched" "Detected in many" 9 "Astrocytes: 580.9;Excitatory neurons: 738.4;Inhibitory neurons: 375.6;Oligodendrocyte precursor cells: 1181.5" "Cancer enriched" "Detected in all" 7 "glioma: 57.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 15 "T-cells: 2.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012606 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in brain" "Cell adhesion" NA NA 110000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 17: Neuronal - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" Nucleoplasm "Vesicles, Plasma membrane" "HPA012606: AB_1854636" "unprognostic (2.66e-1)" "unprognostic (2.65e-1)" "unprognostic (2.52e-3)" "unprognostic (2.18e-2)" "unprognostic (4.08e-3)" "unprognostic (1.01e-2)" "unprognostic (4.47e-3)" "unprognostic (1.66e-1)" "unprognostic (1.73e-1)" "unprognostic (4.81e-2)" "unprognostic (9.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.22e-2)" "unprognostic (9.70e-3)" "unprognostic (6.42e-2)" "unprognostic (6.51e-3)" "unprognostic (3.28e-2)" NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 16.5" "Group enriched" "Detected in many" 13 "Excitatory neurons: 1418.8;Inhibitory neurons: 389.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 53.9" "Lineage enriched" "Detected in many" 5 "monocytes: 53.9" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" "Growth factor" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" 1 Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" NRG2 "Don-1, HRG2, NTAK" ENSG00000158458 "Neuregulin 2" O14511 5 139846779-140043299 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8" "Cell type enhanced" "Detected in many" "Astrocytes: 67.8;Excitatory neurons: 86.9;Inhibitory neurons: 130.9;Oligodendrocyte precursor cells: 133.5;Oligodendrocytes: 47.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038935, HPA047973" Approved Supported Nucleoplasm,Nucleoli "Secreted in other tissues" "Growth factor" No NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 69: Neurons - Neuronal signaling" 1 Nucleoplasm Nucleoli "HPA038935: AB_10672833, HPA047973: AB_2680226" "unprognostic (8.66e-4)" "unprognostic (2.17e-1)" "unprognostic (1.21e-1)" "unprognostic (6.04e-2)" "unprognostic (3.22e-1)" "unprognostic (2.96e-2)" "unprognostic (8.66e-3)" "unprognostic (1.11e-1)" "unprognostic (3.99e-1)" "unprognostic (1.88e-1)" "unprognostic (4.26e-3)" "unprognostic (4.00e-2)" "unprognostic (7.79e-3)" "unprognostic (3.64e-3)" "unprognostic (9.54e-2)" "unprognostic (2.23e-2)" "unprognostic (2.07e-2)" NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3" "Group enriched" "Detected in some" 18 "Astrocytes: 2770.9;Excitatory neurons: 3634.2;Inhibitory neurons: 2955.4;Oligodendrocyte precursor cells: 1102.7" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.1;skin cancer: 2.9" "Adipose subcutaneous - Smooth muscle cells, Liver - Vascular Endothelial cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" "Growth factor" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 6: Leukemia - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" NRG4 HRG4 ENSG00000169752 "Neuregulin 4" Q8WWG1 15 75935969-76059795 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 4.2" "Cell type enhanced" "Detected in many" "Early spermatids: 18.6;Exocrine glandular cells: 22.4;Gastric mucus-secreting cells: 31.2;Oocytes: 27.9;Prostatic glandular cells: 15.6;Rod photoreceptor cells: 28.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010957 Uncertain "Secreted to digestive system" "Growth factor" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 2: Neurons - Nucleosome" "Cluster 56: Non-specific - Sensory perception" "Cluster 45: Non-specific - Mixed function" 4 "HPA010957: AB_1079504" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (3.94e-2)" "unprognostic (1.67e-2)" "unprognostic (5.66e-2)" "unprognostic (4.10e-2)" "unprognostic (1.12e-2)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (2.82e-5)" "unprognostic (1.91e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-5)" "unprognostic (8.28e-2)" "unprognostic (7.45e-2)" "unprognostic (1.08e-2)" "unprognostic (2.06e-1)" NRN1L "MRCC2446, UNQ2446" ENSG00000188038 "Neuritin 1 like" Q496H8 16 67884885-67888855 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 25.7" "Cell type enhanced" "Detected in some" "Astrocytes: 2.8;Oligodendrocytes: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "testis cancer: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041761 Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 25: Bipolar cells - Visual perception" 1 "HPA041761: AB_10961155" "unprognostic (2.79e-2)" "unprognostic (3.32e-1)" "unprognostic (1.19e-1)" "unprognostic (3.99e-2)" "unprognostic (4.85e-1)" NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 336.4;Endothelial cells: 161.7;Hofbauer cells: 118.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.4" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved Uncertain Mitochondria "Secreted in other tissues" Receptor NA NA 780000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 Mitochondria "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 76.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.8;Langerhans cells: 178.1;Lymphatic endothelial cells: 478.9;Ovarian stromal cells: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 122.1" "Breast - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" Receptor NA NA 29000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" NRTN NTN ENSG00000171119 Neurturin Q99748 19 5805067-5828324 "Disease related genes, Predicted secreted proteins" "Growth factor" "Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 24.8;pancreas: 16.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.1;Hepatocytes: 12.5;Rod photoreceptor cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA065260 Approved "Golgi apparatus" "Secreted to blood" "Growth factor" NA NA "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" "Golgi apparatus" "HPA065260: AB_2685448" "unprognostic (4.85e-2)" "unprognostic (1.66e-2)" "unprognostic (2.96e-2)" "prognostic favorable (3.86e-4)" "unprognostic (1.60e-2)" "prognostic favorable (7.23e-4)" "unprognostic (8.21e-3)" "unprognostic (5.60e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.38e-1)" "unprognostic (2.08e-2)" "unprognostic (1.28e-2)" "unprognostic (6.78e-3)" "unprognostic (3.39e-1)" "unprognostic (1.65e-1)" "unprognostic (1.22e-1)" "unprognostic (4.32e-2)" NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Intellectual disability, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 78.6" "Group enriched" "Detected in many" 5 "Astrocytes: 3817.5;Excitatory neurons: 3094.7;Inhibitory neurons: 2015.5;Oligodendrocyte precursor cells: 4595.9" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.5" "Cancer enhanced" "Detected in some" "lung cancer: 4.4;thyroid cancer: 4.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells, Pancreas - Alpha cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 1400000 "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 65: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 1 "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" NSUN2 "FLJ20303, Misu, MRT5, SAKI, TRM4" ENSG00000037474 "NOP2/Sun RNA methyltransferase 2" Q08J23 5 6599239-6633291 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis, tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037896 Supported Uncertain Nucleoplasm "Intracellular and membrane" Enzyme NA NA 110000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 29: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA037896: AB_10670532" "unprognostic (3.99e-2)" "unprognostic (5.73e-2)" "unprognostic (1.44e-1)" "unprognostic (7.66e-3)" "unprognostic (8.56e-2)" "unprognostic (5.21e-2)" "unprognostic (1.44e-3)" "unprognostic (5.12e-2)" "unprognostic (4.48e-2)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (2.48e-2)" "prognostic unfavorable (5.69e-5)" "unprognostic (1.98e-1)" "unprognostic (1.47e-1)" "unprognostic (4.30e-3)" "unprognostic (1.70e-2)" NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014130-33062796 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 85.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010520, HPA010630, HPA029058" Uncertain Supported "Nucleoplasm,Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Enzyme NA NA 10000 "Cluster 20: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 57: Platelets - Hemostasis" 2 "Endoplasmic reticulum, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA010520: , HPA010630: AB_2668319, HPA029058: AB_10601380" "unprognostic (7.50e-2)" "unprognostic (3.10e-1)" "unprognostic (1.14e-1)" "unprognostic (2.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (3.25e-2)" "unprognostic (3.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (9.37e-2)" "unprognostic (2.05e-1)" "unprognostic (2.12e-3)" "unprognostic (3.43e-3)" NT5DC3 "FLJ11266, TU12B1-TY" ENSG00000111696 "5'-nucleotidase domain containing 3" Q86UY8 12 103770453-103841234 "Metabolic proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 77.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 35.4;Mucus glandular cells: 59.1;Oligodendrocyte precursor cells: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041634 Approved Mitochondria,Cytosol "Secreted - unknown location" Enzyme NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 37: Glandular & Luminal cells - Unknown function" Mitochondria Cytosol "HPA041634: AB_10795597" "unprognostic (2.61e-2)" "unprognostic (1.16e-1)" "unprognostic (7.30e-2)" "unprognostic (2.72e-1)" "unprognostic (8.45e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.57e-1)" "unprognostic (2.19e-1)" "unprognostic (2.45e-2)" "unprognostic (5.43e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.60e-3)" "unprognostic (7.42e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (8.11e-4)" NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 108.6;retina: 91.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 62.3;Lymphatic endothelial cells: 88.9;Oligodendrocyte precursor cells: 57.5;Paneth cells: 56.8;Rod photoreceptor cells: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.1;naive CD8 T-cell: 30.8" "Group enriched" "Detected in many" 41 "B-cells: 33.1;T-cells: 30.8" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 320.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 3000000 "Cluster 34: B-cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 1 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" NTF3 NGF2 ENSG00000185652 "Neurotrophin 3" P20783 12 5432108-5521536 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 12.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.5;Basal squamous epithelial cells: 48.1;Breast myoepithelial cells: 11.6;Ovarian stromal cells: 25.5;Peritubular cells: 10.8;Sertoli cells: 13.6;Smooth muscle cells: 23.5" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in some" 7 "cerebellum: 6.9;cerebral cortex: 2.5;hippocampal formation: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebellum: 6.5;cerebral cortex: 2.6;hippocampal formation: 3.0" HPA032001 Uncertain Approved Vesicles "Secreted in other tissues" "Growth factor" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 Vesicles "HPA032001: AB_2674106" "unprognostic (3.04e-2)" "unprognostic (7.46e-2)" "unprognostic (7.33e-3)" "unprognostic (4.66e-3)" "unprognostic (8.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.36e-3)" "unprognostic (7.68e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (2.20e-1)" "unprognostic (7.77e-4)" "unprognostic (4.02e-3)" "unprognostic (1.92e-1)" "unprognostic (8.06e-3)" "unprognostic (4.51e-3)" NTF4 "GLC1O, NT-4/5, NTF5" ENSG00000225950 "Neurotrophin 4" P34130 19 49061066-49065076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 19.5;skeletal muscle: 13.9;skin 1: 15.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 6.7;Basal respiratory cells: 23.0;Breast myoepithelial cells: 27.7;Club cells: 8.2;Cytotrophoblasts: 13.6;Ionocytes: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.9" "Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049376 Approved "Golgi apparatus" "Secreted in other tissues" "Growth factor" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 3 "Golgi apparatus" "HPA049376: AB_2680735" "unprognostic (4.15e-2)" "unprognostic (1.07e-1)" "unprognostic (9.27e-4)" "unprognostic (1.76e-4)" "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.73e-2)" "unprognostic (4.87e-3)" "unprognostic (3.90e-4)" "unprognostic (2.97e-1)" "unprognostic (1.40e-3)" "unprognostic (3.71e-2)" "unprognostic (2.49e-1)" "unprognostic (1.89e-2)" "unprognostic (2.46e-3)" NTM "CEPU-1, HNT, IGLON2, NTRI" ENSG00000182667 Neurotrimin Q9P121 11 131370478-132336822 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 89.4;retina: 70.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2052.6;Cone photoreceptor cells: 479.2;Excitatory neurons: 629.2;Inhibitory neurons: 1013.1;Oligodendrocyte precursor cells: 1811.6;Oligodendrocytes: 1170.5;Rod photoreceptor cells: 1290.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 175 "plasmacytoid DC: 17.5" "Lineage enriched" "Detected in single" 175 "dendritic cells: 17.5" "Cancer enhanced" "Detected in many" "Bone cancer: 21.7;Brain cancer: 21.9;Sarcoma: 22.1;thyroid cancer: 21.7" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB024875 Enhanced "Intracellular and membrane" "Cell adhesion" NA NA 58000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 28: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" 4 "CAB024875: " "unprognostic (1.52e-2)" "unprognostic (4.38e-3)" "unprognostic (1.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.25e-1)" "unprognostic (1.07e-1)" "unprognostic (9.99e-3)" "unprognostic (9.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.52e-2)" "unprognostic (4.29e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.10e-8)" "unprognostic (4.60e-3)" "unprognostic (1.37e-1)" "unprognostic (2.94e-1)" "unprognostic (9.31e-3)" NTN1 "NET1, NTN1L" ENSG00000065320 "Netrin 1" O95631 17 9021510-9244000 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.4" "Cell type enhanced" "Detected in many" "Ionocytes: 33.9;Lymphatic endothelial cells: 38.4;Oligodendrocyte precursor cells: 128.8;Oocytes: 69.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 22.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Fibroblasts, Skin - Fibroblast_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056419 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" "Secreted to extracellular matrix" Other NA NA 110000 "Cluster 30: Heart muscle - Heart development" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 Cytosol "Nucleoplasm, Actin filaments" "HPA056419: AB_2683124" "unprognostic (2.72e-1)" "unprognostic (2.59e-2)" "unprognostic (7.12e-2)" "unprognostic (5.25e-2)" "unprognostic (2.51e-1)" "unprognostic (9.33e-3)" "unprognostic (9.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.15e-1)" "unprognostic (2.49e-2)" "unprognostic (2.20e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-3)" "unprognostic (8.31e-3)" NTN3 NTN2L ENSG00000162068 "Netrin 3" O00634 16 2471297-2474145 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Paneth cells: 1.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.3;Neuroblastoma: 3.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050817 Uncertain "Secreted in brain" "No annotated function" NA NA "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 1: Neuronal - Visual perception" "Cluster 5: Enterocytes - Absorption" "HPA050817: AB_2681247" "unprognostic (2.60e-2)" "unprognostic (1.95e-2)" "unprognostic (1.79e-1)" "unprognostic (9.17e-2)" "unprognostic (6.44e-2)" "unprognostic (2.23e-2)" "unprognostic (9.62e-3)" "unprognostic (2.11e-1)" "unprognostic (4.55e-2)" "unprognostic (6.95e-2)" "unprognostic (5.58e-2)" "unprognostic (2.34e-1)" "unprognostic (1.35e-2)" "unprognostic (3.26e-2)" "unprognostic (6.68e-2)" "unprognostic (2.39e-2)" "unprognostic (6.61e-2)" NTN4 ENSG00000074527 "Netrin 4" Q9HB63 12 95657807-95791189 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 176.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 180.9;Oligodendrocyte precursor cells: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "MAIT T-cell: 1.6" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049832 Approved "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 47: Spleen - Immune response" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 8 "HPA049832: AB_2680905" "unprognostic (3.08e-1)" "unprognostic (2.17e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.67e-1)" "unprognostic (3.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (2.85e-1)" "prognostic favorable (8.12e-9)" "unprognostic (3.52e-2)" "unprognostic (7.08e-2)" "unprognostic (1.93e-1)" "prognostic favorable (6.67e-5)" NTN5 ENSG00000142233 "Netrin 5" Q8WTR8 19 48661407-48673081 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 4.9" "Cell type enhanced" "Detected in some" "Astrocytes: 4.3;Bipolar cells: 5.6;Horizontal cells: 10.1;Late spermatids: 14.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Sarcoma: 4.3" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Region enriched" "Detected in some" 5 "cerebellum: 5.0" "Secreted in brain" "Developmental protein" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "unprognostic (8.20e-3)" "unprognostic (5.54e-2)" "unprognostic (5.26e-6)" "unprognostic (4.48e-2)" "unprognostic (2.23e-1)" "unprognostic (4.33e-2)" "unprognostic (3.18e-2)" "unprognostic (1.73e-2)" "unprognostic (2.89e-3)" "unprognostic (9.40e-3)" "unprognostic (1.74e-3)" "unprognostic (4.60e-1)" "unprognostic (5.11e-2)" "unprognostic (1.60e-3)" "unprognostic (3.51e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-3)" NTNG1 "KIAA0976, Lmnt1" ENSG00000162631 "Netrin G1" Q9Y2I2 1 107140007-107484923 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.5;retina: 10.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 118.2;Inhibitory neurons: 155.1;Oligodendrocyte precursor cells: 399.0" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "thalamus: 164.8" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.1" "Lineage enriched" "Detected in single" 4 "B-cells: 1.1" "Cancer enhanced" "Detected in many" "Bone cancer: 10.1" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "hippocampal formation: 26.0;midbrain: 79.9;pons: 71.8;thalamus: 99.3" HPA065954 Supported "Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" 1 "Plasma membrane" "HPA065954: AB_2685585" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.67e-2)" "unprognostic (9.38e-5)" "unprognostic (1.93e-3)" "unprognostic (9.87e-3)" "unprognostic (3.34e-1)" "unprognostic (8.38e-3)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-4)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (1.93e-5)" NTNG2 "KIAA1857, Lmnt2, NTNG1" ENSG00000196358 "Netrin G2" Q96CW9 9 132162058-132244526 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 24.8;brain: 19.1;retina: 20.1" "Cell type enhanced" "Detected in many" "Astrocytes: 33.1;Bipolar cells: 67.4;Cone photoreceptor cells: 152.9;Rod photoreceptor cells: 117.1" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebral cortex: 149.3" "Immune cell enriched" "Detected in single" 5 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cancer enhanced" "Detected in some" "Leukemia: 4.7" "Prostate - Prostate glandular cells, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024306, HPA071290" Approved Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" 1 Vesicles "Plasma membrane" "HPA024306: , HPA071290: AB_2686381" "unprognostic (5.01e-2)" "unprognostic (2.95e-2)" "unprognostic (4.12e-2)" "unprognostic (1.01e-1)" "unprognostic (3.59e-1)" "unprognostic (7.67e-2)" "unprognostic (2.73e-2)" "unprognostic (2.87e-1)" "unprognostic (4.86e-2)" "unprognostic (1.47e-1)" "unprognostic (2.62e-2)" "prognostic favorable (6.06e-4)" "unprognostic (9.30e-12)" "unprognostic (1.66e-1)" "unprognostic (3.23e-1)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" NTS ENSG00000133636 Neurotensin P30990 12 85874295-85882992 "Predicted secreted proteins" Vasoactive "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 161.0" "Cell type enriched" "Detected in some" 132 "Enteroendocrine cells: 17404.5" "Cancer enhanced" "Detected in many" "lung cancer: 155.1" "Group enriched" "Detected in all" 4 "cerebral cortex: 20.0;hypothalamus: 44.0;medulla oblongata: 27.4;midbrain: 20.6;thalamus: 59.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 286.9;ovarian cancer: 348.2;testis cancer: 189.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 88.3" "HPA026664, HPA071012" Enhanced Supported Vesicles "Secreted to digestive system" Other NA NA 1600000 "Cluster 25: Small intestine - Absorption" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" 2 Vesicles "HPA026664: AB_2671936, HPA071012: " "unprognostic (3.63e-1)" "prognostic favorable (9.94e-5)" "unprognostic (8.18e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (7.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-3)" "unprognostic (8.83e-2)" "unprognostic (1.74e-2)" "unprognostic (3.76e-2)" "unprognostic (1.30e-6)" "unprognostic (2.94e-2)" "unprognostic (2.25e-1)" "unprognostic (2.17e-1)" "unprognostic (7.48e-2)" NUBPL "C14orf127, FLJ12660, huInd1, IND1" ENSG00000151413 "NUBP iron-sulfur cluster assembly factor, mitochondrial" Q8TB37 14 31489956-31861224 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 64.7;Inhibitory neurons: 71.7;Oligodendrocyte precursor cells: 82.5;Oligodendrocytes: 92.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029203 Approved Supported Mitochondria "Intracellular and membrane" "No annotated function" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 8: Neurons - Neuronal signaling" 1 Mitochondria "HPA029203: AB_10602810" "unprognostic (1.49e-1)" "unprognostic (1.71e-2)" "unprognostic (5.21e-3)" "unprognostic (8.28e-2)" "unprognostic (8.25e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "unprognostic (1.93e-2)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "prognostic favorable (3.64e-8)" "unprognostic (2.82e-2)" "unprognostic (6.60e-2)" "unprognostic (3.67e-3)" "unprognostic (1.56e-2)" NUCB1 "Calnuc, NUC" ENSG00000104805 "Nucleobindin 1" Q02818 19 48900050-48923473 "Plasma proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 458.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008176 Supported Supported "Golgi apparatus,Microtubules" "Secreted to blood" Other NA NA 27000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Proximal enterocytes - Digestion" 1 "Golgi apparatus" Microtubules "HPA008176: AB_1845923" "unprognostic (2.13e-1)" "unprognostic (2.83e-1)" "unprognostic (4.36e-3)" "unprognostic (6.28e-2)" "unprognostic (1.06e-2)" "unprognostic (2.95e-1)" "unprognostic (6.86e-2)" "unprognostic (1.98e-1)" "unprognostic (9.51e-2)" "unprognostic (8.14e-3)" "unprognostic (2.34e-3)" "unprognostic (9.89e-2)" "unprognostic (5.04e-3)" "unprognostic (1.19e-1)" "unprognostic (1.39e-1)" "unprognostic (8.90e-3)" "unprognostic (3.41e-1)" NUCB2 NEFA ENSG00000070081 "Nucleobindin 2" P80303 11 17208153-17349980 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 478.8;salivary gland: 493.3" "Cell type enhanced" "Detected in all" "Early spermatids: 641.1;Late spermatids: 617.5;Serous glandular cells: 1178.3;Syncytiotrophoblasts: 1600.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Pancreas - Exocrine glandular cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008395, CAB015931, CAB079781" Enhanced Supported Enhanced "Golgi apparatus" "Secreted to blood" Other NA NA 1250000 690000 "Cluster 30: Non-specific - DNA binding" "Cluster 15: Pancreas - Proteolysis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "Golgi apparatus" "CAB015931: , CAB079781: AB_2313672, HPA008395: AB_1854683" "unprognostic (2.49e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.27e-6)" "unprognostic (5.24e-3)" "unprognostic (2.51e-1)" "unprognostic (3.96e-3)" "unprognostic (3.66e-3)" "unprognostic (1.81e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.46e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (4.78e-2)" "unprognostic (8.02e-3)" NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422573-87459455 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" Enzyme NA NA 9900 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Protein processing" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: AB_10696790, HPA044866: AB_2679120, HPA078535: AB_2686885" "unprognostic (7.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.45e-2)" "prognostic favorable (7.43e-5)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-2)" "unprognostic (4.23e-1)" "prognostic favorable (8.00e-11)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-3)" NUP155 "KIAA0791, N155" ENSG00000113569 "Nucleoporin 155" O75694 5 37288137-37371106 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Atrial fibrillation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 68.8" "Cell type enhanced" "Detected in many" "Early spermatids: 68.7;Late spermatids: 102.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037775 Enhanced Enhanced "Nuclear membrane" "Intracellular and membrane" Transport NA NA 28000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Testis - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" 3 "Nuclear membrane" "HPA037775: AB_10671885" "unprognostic (1.10e-2)" "unprognostic (7.94e-2)" "unprognostic (1.28e-2)" "unprognostic (8.58e-3)" "unprognostic (7.14e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (1.35e-6)" "unprognostic (2.18e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (2.51e-2)" "unprognostic (9.49e-2)" "unprognostic (1.49e-2)" "unprognostic (6.80e-2)" "unprognostic (2.27e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" NXPE1 "FAM55A, MGC34290" ENSG00000095110 "Neurexophilin and PC-esterase domain family member 1" Q8N323 11 114518934-114559881 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 72.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 34.5;Early spermatids: 88.3;Enteroendocrine cells: 19.3;Intestinal goblet cells: 53.3;Late spermatids: 50.3;Paneth cells: 22.6;Undifferentiated cells: 25.5" "Cancer enriched" "Detected in single" 23 "colorectal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" HPA049133 Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 45: Intestine - Digestion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 5 "HPA049133: AB_2680647" "unprognostic (2.81e-1)" "unprognostic (2.19e-3)" "unprognostic (3.40e-3)" "unprognostic (4.10e-1)" "unprognostic (1.05e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (3.40e-2)" "unprognostic (1.76e-1)" NXPE3 "FAM55C, MGC15606" ENSG00000144815 "Neurexophilin and PC-esterase domain family member 3" Q969Y0 3 101779177-101843743 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 57.4;tongue: 49.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.7;Oligodendrocytes: 165.3;Plasma cells: 68.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036259 Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" "No annotated function" NA NA 12000 "Cluster 6: T-cells - T-cell receptor" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 51: Oligodendrocytes - Unknown function" 4 Vesicles Nucleoplasm "HPA036259: AB_10671838" "unprognostic (3.30e-1)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (4.42e-5)" "unprognostic (4.98e-2)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (7.42e-2)" "unprognostic (1.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.57e-3)" "unprognostic (3.43e-1)" "prognostic unfavorable (7.76e-6)" "unprognostic (2.89e-1)" "unprognostic (5.23e-2)" "unprognostic (1.77e-1)" "unprognostic (8.75e-3)" NXPE4 "C11orf33, FAM55D, FLJ20127" ENSG00000137634 "Neurexophilin and PC-esterase domain family member 4" Q6UWF7 11 114570591-114595786 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 115.8;salivary gland: 75.0" "Group enriched" "Detected in some" 17 "Distal enterocytes: 130.4;Enteroendocrine cells: 74.7;Intestinal goblet cells: 81.0;Paneth cells: 34.5;Serous glandular cells: 34.5;Undifferentiated cells: 61.3" "Cancer enriched" "Detected in some" 15 "colorectal cancer: 13.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells, Colon - Colon enterocytes" "Low region specificity" "Detected in all" HPA042801 Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 45: Intestine - Digestion" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA042801: AB_10793986" "unprognostic (1.35e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-3)" "unprognostic (1.27e-1)" "unprognostic (3.51e-3)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (7.47e-3)" "unprognostic (4.36e-2)" "unprognostic (2.05e-1)" NXPH1 ENSG00000122584 "Neurexophilin 1" P58417 7 8433609-8752961 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "adrenal gland: 40.6;brain: 27.8" "Group enriched" "Detected in some" 32 "Inhibitory neurons: 1425.9;Oligodendrocyte precursor cells: 1407.9" "Group enriched" "Detected in some" 62 "breast cancer: 2.3;glioma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.7;Neuroblastoma: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" "No annotated function" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 8: Neurons - Neuronal signaling" "unprognostic (2.84e-2)" "unprognostic (1.30e-1)" "unprognostic (3.74e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-2)" "unprognostic (1.46e-4)" "unprognostic (1.47e-1)" "unprognostic (3.01e-2)" "unprognostic (5.32e-1)" "unprognostic (9.46e-2)" NXPH2 NPH2 ENSG00000144227 "Neurexophilin 2" O95156 2 138669157-138780390 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 2.8;kidney: 3.9;ovary: 4.2;retina: 2.2" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 148.3" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 4 "medulla oblongata: 15.6;midbrain: 16.2;pons: 27.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.6;Rhabdoid: 6.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Intercalated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034759 Approved "Secreted in brain" "No annotated function" NA Yes "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" "HPA034759: AB_10669732" "unprognostic (5.83e-2)" "unprognostic (8.83e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.80e-1)" NXPH3 NPH3 ENSG00000182575 "Neurexophilin 3" O95157 17 49575871-49583827 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 13.3;Bipolar cells: 18.2;Fibroblasts: 6.9;Muller glia cells: 8.4;Peritubular cells: 13.5;Smooth muscle cells: 10.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.5" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 54.8" HPA073819 Approved "Vesicles,Mitotic spindle" "Secreted in brain" "No annotated function" Yes NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 32: Smooth muscle cells - Muscle contraction" Vesicles "Mitotic spindle" "HPA073819: " "unprognostic (2.39e-2)" "unprognostic (4.75e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-1)" "unprognostic (1.92e-1)" "unprognostic (3.30e-1)" "unprognostic (1.97e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-2)" "unprognostic (6.33e-2)" "unprognostic (4.62e-4)" "unprognostic (2.59e-2)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (5.05e-3)" NXPH4 NPH4 ENSG00000182379 "Neurexophilin 4" O95158 12 57216794-57226449 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.9;skin 1: 18.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 10.2;Cytotrophoblasts: 26.9;Muller glia cells: 16.9;Oocytes: 16.2;Prostatic glandular cells: 10.3;Syncytiotrophoblasts: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Secreted in brain" "No annotated function" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 24: Cytotrophoblasts - Mitochondria" "unprognostic (1.08e-2)" "unprognostic (4.84e-2)" "unprognostic (2.70e-3)" "prognostic unfavorable (6.21e-4)" "prognostic unfavorable (5.42e-4)" "unprognostic (1.16e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (3.07e-1)" "unprognostic (1.51e-2)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (6.77e-2)" "prognostic unfavorable (7.68e-6)" "unprognostic (7.83e-2)" "unprognostic (2.73e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-3)" NYX "CLRP, CSNB1, CSNB1A, CSNB4" ENSG00000188937 Nyctalopin Q9GZU5 X 41447343-41475710 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "Bipolar cells: 12.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "choroid plexus: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.2" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Other NA NA "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 25: Bipolar cells - Visual perception" 2 "unprognostic (3.27e-2)" "unprognostic (6.72e-2)" "unprognostic (4.21e-2)" "unprognostic (4.10e-4)" "unprognostic (1.83e-1)" "unprognostic (3.96e-2)" "unprognostic (1.80e-1)" OAF MGC52117 ENSG00000184232 "Out at first homolog" Q86UD1 11 120211032-120230334 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 387.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 113.4;Fibroblasts: 113.8;Hepatocytes: 195.4;Lymphatic endothelial cells: 192.8;Muller glia cells: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.3;intermediate monocyte: 1.6;myeloid DC: 2.4" "Group enriched" "Detected in many" 14 "dendritic cells: 2.4;monocytes: 3.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047412 Uncertain Approved Nucleoplasm "Secreted - unknown location" "No annotated function" NA NA 69000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm "HPA047412: AB_10960631" "unprognostic (1.59e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (2.80e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (2.11e-1)" "unprognostic (3.98e-3)" "unprognostic (5.09e-2)" "unprognostic (3.90e-2)" "unprognostic (3.28e-2)" "unprognostic (1.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.12e-2)" "unprognostic (7.15e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" OAS1 "IFI-4, OIAS, OIASI" ENSG00000089127 "2'-5'-oligoadenylate synthetase 1" P00973 12 112905856-112933219 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 88.5;urinary bladder: 106.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 146.4;Hofbauer cells: 108.6;monocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 575.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003657, CAB021104" Uncertain Supported Nucleoplasm,Cytosol "Intracellular and membrane" Immunity NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 58: Macrophages - Innate immune response" 4 "Nucleoplasm, Cytosol" "CAB021104: AB_10057722, HPA003657: AB_1854747" "unprognostic (1.03e-1)" "unprognostic (6.59e-2)" "unprognostic (8.56e-3)" "unprognostic (2.20e-3)" "unprognostic (2.78e-1)" "unprognostic (1.30e-1)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.20e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (5.37e-2)" "unprognostic (1.63e-2)" "unprognostic (6.91e-2)" "unprognostic (3.68e-2)" "unprognostic (5.67e-2)" "prognostic favorable (6.12e-6)" OBP2A "hOBPIIa, LCN13, OBP" ENSG00000122136 "Odorant binding protein 2A" Q9NY56 9 135546126-135549969 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "fallopian tube: 24.1" "Cell type enriched" "Detected in some" 8 "Secretory cells: 43.7" "Cancer enriched" "Detected in some" 6 "ovarian cancer: 18.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.8;thyroid cancer: 2.7" "Skin - Eccrine sweat gland cells" HPA055955 Uncertain "Secreted in other tissues" Transport NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA055955: AB_2682985" "unprognostic (2.30e-1)" "unprognostic (3.68e-1)" "unprognostic (4.63e-1)" "unprognostic (1.66e-2)" "unprognostic (2.17e-1)" "unprognostic (3.20e-1)" "unprognostic (2.75e-1)" "unprognostic (7.65e-2)" "unprognostic (2.23e-2)" "unprognostic (8.27e-2)" "unprognostic (1.91e-1)" "unprognostic (6.83e-11)" "unprognostic (5.17e-2)" "unprognostic (3.61e-1)" "unprognostic (1.26e-1)" "unprognostic (3.84e-1)" OBP2B "hOBPIIb, LCN14" ENSG00000171102 "Odorant binding protein 2B" Q9NPH6 9 133205277-133209250 "Predicted secreted proteins" "Olfaction, Sensory transduction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 2.4;testis: 9.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 22.8;Breast myoepithelial cells: 29.2;Granulosa cells: 12.6;Melanocytes: 5.2;Secretory cells: 8.5;Sertoli cells: 10.9" "Group enriched" "Detected in many" 8 "breast cancer: 7.8;endometrial cancer: 16.2;ovarian cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells" "Secreted in other tissues" Transport NA NA "Cluster 21: Testis - Unknown function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "unprognostic (1.40e-1)" "unprognostic (5.70e-2)" "unprognostic (9.45e-3)" "unprognostic (6.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.30e-1)" "unprognostic (7.03e-2)" "unprognostic (6.82e-6)" "unprognostic (2.00e-2)" "unprognostic (1.12e-1)" "unprognostic (2.53e-1)" OC90 PLA2L ENSG00000253117 "Otoconin 90" Q02509 8 132024216-132059382 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in other tissues" "No annotated function" NA NA "Cluster 34: Testis cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" "unprognostic (1.92e-1)" "unprognostic (2.93e-1)" OCLN PPP1R115 ENSG00000197822 Occludin Q16625 5 69492292-69558104 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 30.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 103.4;Distal enterocytes: 84.8;Glandular and luminal cells: 119.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.6" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.6" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005933, CAB013075, CAB068212, CAB068213, CAB068214" Enhanced Supported "Plasma membrane,Cell Junctions" "Intracellular and membrane" "No annotated function" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Glandular & Luminal cells - Unknown function" 5 "Plasma membrane, Cell Junctions" "CAB013075: AB_2533101, CAB068212: AB_2665711, CAB068213: AB_2665712, CAB068214: AB_2665713, HPA005933: AB_1079520" "unprognostic (2.28e-1)" "unprognostic (1.88e-1)" "unprognostic (2.50e-2)" "unprognostic (9.94e-2)" "unprognostic (3.65e-1)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.08e-2)" "unprognostic (8.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.58e-2)" "unprognostic (3.48e-1)" "prognostic favorable (6.59e-11)" "unprognostic (2.83e-1)" "unprognostic (4.01e-1)" "unprognostic (1.33e-1)" "unprognostic (3.35e-1)" ODAM "APin, FLJ20513" ENSG00000109205 "Odontogenic, ameloblast associated" A1E959 4 70195725-70204576 "Cancer-related genes, Predicted intracellular proteins" Biomineralization "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "salivary gland: 360.6" "Cell type enriched" "Detected in some" 5 "Mucus glandular cells: 383.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "medulla oblongata: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 8.0;colorectal cancer: 8.7;Gastric cancer: 21.4" "Colon - Colon enteroendocrine cells, Stomach - Parietal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036279, HPA036543, HPA070297" Supported Nucleoplasm,Cytosol "Intracellular and membrane" Other NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" 9 Nucleoplasm Cytosol "HPA036279: , HPA036543: AB_10669797, HPA070297: " "unprognostic (2.34e-2)" "unprognostic (2.43e-1)" "unprognostic (1.26e-1)" "unprognostic (1.75e-1)" "unprognostic (3.34e-3)" "unprognostic (1.06e-1)" "unprognostic (1.88e-2)" "unprognostic (3.47e-1)" "unprognostic (3.08e-1)" "unprognostic (3.03e-1)" "unprognostic (2.72e-1)" "unprognostic (1.86e-2)" "unprognostic (2.50e-2)" ODAPH "AI2A4, C4orf26, FLJ23657" ENSG00000174792 "Odontogenesis associated phosphoprotein" Q17RF5 4 75556048-75565871 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 5.7" "Cell type enhanced" "Detected in some" "Early spermatids: 4.5;Extravillous trophoblasts: 10.7;Plasma cells: 5.4;Syncytiotrophoblasts: 26.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.1;urothelial cancer: 0.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 34 "basophil: 10.7" "Lineage enriched" "Detected in single" 34 "granulocytes: 10.7" "Cancer enhanced" "Detected in many" "Bladder cancer: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" "No annotated function" NA NA "Cluster 32: Basophils - Transcription" "Cluster 58: Placenta - Pregnancy" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 "unprognostic (1.13e-1)" "unprognostic (4.45e-3)" "unprognostic (3.78e-1)" "unprognostic (1.66e-1)" "unprognostic (6.12e-2)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (2.44e-1)" "unprognostic (3.87e-2)" "unprognostic (5.30e-2)" "unprognostic (3.43e-1)" "unprognostic (1.17e-7)" "unprognostic (8.31e-2)" "unprognostic (2.70e-2)" "unprognostic (8.40e-4)" "unprognostic (6.53e-3)" OGN "mimecan, OIF, SLRR3A" ENSG00000106809 Osteoglycin P20774 9 92383268-92404696 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 208.3;ovary: 229.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 107.0;Fibroblasts: 220.7;Leydig cells: 163.4;Mesothelial cells: 665.8;Ovarian stromal cells: 237.9;Peritubular cells: 199.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.7" "Lineage enriched" "Detected in single" 9 "T-cells: 1.7" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 22.0" "Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013132 Approved Supported "Endoplasmic reticulum" "Secreted in other tissues" "Growth factor" NA NA 170000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 62: Connective tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA013132: AB_1854825" "unprognostic (2.31e-1)" "unprognostic (3.94e-3)" "unprognostic (1.74e-1)" "unprognostic (2.08e-2)" "unprognostic (2.60e-1)" "unprognostic (2.70e-1)" "unprognostic (1.44e-4)" "unprognostic (4.42e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.37e-3)" "unprognostic (3.86e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (2.03e-4)" OIT3 "FLJ39116, LZP" ENSG00000138315 "Oncoprotein induced transcript 3" Q8WWZ8 10 72893584-72933036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 107.5" "Group enriched" "Detected in some" 8 "Endothelial cells: 96.8;Fibroblasts: 45.0;Kupffer cells: 61.7" "Cancer enriched" "Detected in many" 4 "liver cancer: 4.6" "Region enhanced" "Detected in some" "cerebellum: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "liver cancer: 1.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" "No annotated function" NA NA 52000000 "Cluster 31: Liver - Plasma proteins" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 9 "unprognostic (2.42e-2)" "unprognostic (6.76e-2)" "unprognostic (7.98e-4)" "unprognostic (9.26e-2)" "unprognostic (9.47e-4)" "unprognostic (3.05e-1)" "unprognostic (4.33e-2)" "unprognostic (1.99e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (8.50e-3)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" "unprognostic (1.35e-1)" "unprognostic (2.44e-1)" "unprognostic (3.68e-3)" "unprognostic (1.19e-1)" OLFM1 "AMY, NOE1, NOELIN, OlfA" ENSG00000130558 "Olfactomedin 1" Q99784 9 135075422-135121180 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 943.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 93.5;Endothelial cells: 104.4;Excitatory neurons: 186.8;Inhibitory neurons: 67.0;Schwann cells: 73.3" "Cancer enhanced" "Detected in all" "glioma: 18.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;intermediate monocyte: 2.8;myeloid DC: 2.6" "Group enriched" "Detected in many" 27 "dendritic cells: 2.6;monocytes: 2.8" "Cancer enhanced" "Detected in many" "Bone cancer: 111.1;Neuroblastoma: 78.3" "Kidney - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057444 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in brain" "Developmental protein" NA NA 200000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 1 Nucleoli "Nucleoplasm, Cytosol" "HPA057444: AB_2683443" "unprognostic (6.77e-2)" "prognostic favorable (7.14e-4)" "unprognostic (1.01e-1)" "unprognostic (3.76e-2)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.08e-1)" "unprognostic (1.30e-1)" "unprognostic (3.69e-3)" "unprognostic (2.67e-1)" "unprognostic (6.04e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (9.46e-3)" "unprognostic (4.60e-2)" "unprognostic (1.51e-1)" "unprognostic (6.20e-2)" "unprognostic (7.53e-4)" OLFM2 "NOE2, OlfC" ENSG00000105088 "Olfactomedin 2" O95897 19 9853718-9936515 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 176.5;skin 1: 87.9" "Cell type enhanced" "Detected in many" "Astrocytes: 102.8;Basal keratinocytes: 69.3;Inhibitory neurons: 48.8;Late spermatids: 48.1;Muller glia cells: 85.4;Oligodendrocyte precursor cells: 117.0;Suprabasal keratinocytes: 64.0" "Cancer enhanced" "Detected in all" "glioma: 96.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 49.8" "Group enriched" "Detected in many" 26 "granulocytes: 49.8;T-cells: 17.0" "Cancer enhanced" "Detected in many" "Bone cancer: 39.5" "Breast - Adipocytes (Breast), Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049961, HPA057771" Uncertain Supported Nucleoplasm "Secreted in other tissues" "No annotated function" NA NA 2700000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 10: Muller glia cells - Visual perception" 2 Nucleoplasm "HPA049961: AB_2680972, HPA057771: AB_2683524" "unprognostic (1.42e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.99e-2)" "unprognostic (5.91e-2)" "unprognostic (3.39e-2)" "unprognostic (8.78e-2)" "unprognostic (4.47e-2)" "unprognostic (8.04e-2)" "unprognostic (4.03e-2)" "unprognostic (1.41e-3)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.23e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" OLFM3 NOE3 ENSG00000118733 "Olfactomedin 3" Q96PB7 1 101802560-101996926 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 18.0;retina: 7.1" "Group enriched" "Detected in some" 11 "Excitatory neurons: 630.5;Inhibitory neurons: 166.6" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 36.2" "Colon - Colon enteroendocrine cells" "Region enhanced" "Detected in all" "cerebellum: 177.3" "Low region specificity" "Detected in all" HPA050297 Uncertain Vesicles "Secreted in brain" "No annotated function" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 2 Vesicles "HPA050297: " "unprognostic (4.19e-1)" "unprognostic (4.19e-4)" "unprognostic (1.26e-1)" "unprognostic (4.61e-2)" "unprognostic (2.93e-1)" "unprognostic (1.47e-2)" "unprognostic (3.58e-4)" "unprognostic (2.48e-1)" "unprognostic (5.68e-2)" OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1259.1;pancreas: 651.3" "Cell type enhanced" "Detected in many" "Club cells: 901.6;Ductal cells: 585.6;Enteroendocrine cells: 418.7;Exocrine glandular cells: 2054.7;Undifferentiated cells: 2297.1" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "colorectal cancer: 123.7;Gastric cancer: 42.1" "Colon - Colon enterocytes, Lung - Neutrophil_1, Prostate - Urothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" "Cell adhesion" Yes NA 9300 "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 24 "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 65.0" "Group enriched" "Detected in some" 4 "Endometrial stromal cells: 13.9;Fibroblasts: 47.2;Leydig cells: 41.5;Lymphatic endothelial cells: 17.7;Mesothelial cells: 13.3;Ovarian stromal cells: 28.4;Peritubular cells: 38.2;Smooth muscle cells: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 18.4" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 6 "spinal cord: 3.6" HPA058824 Approved "Secreted - unknown location" "No annotated function" NA NA 260000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 72: Neuronal - Signal transduction" "Cluster 53: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" OLFML2A FLJ00237 ENSG00000185585 "Olfactomedin like 2A" Q68BL7 9 124777133-124814885 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 20.2;Fibroblasts: 21.8;Lymphatic endothelial cells: 45.1;Melanocytes: 37.8;Schwann cells: 47.2;Smooth muscle cells: 25.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Skin - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021180, HPA022254" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" "No annotated function" NA NA 240000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA021180: AB_1854790, HPA022254: AB_1854791" "unprognostic (1.12e-1)" "unprognostic (3.07e-2)" "unprognostic (3.16e-1)" "unprognostic (2.45e-1)" "unprognostic (4.01e-2)" "unprognostic (1.27e-1)" "unprognostic (1.15e-1)" "unprognostic (3.00e-1)" "unprognostic (1.26e-3)" "unprognostic (7.53e-2)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (3.73e-5)" "unprognostic (5.72e-3)" "unprognostic (3.30e-2)" "unprognostic (7.91e-2)" "unprognostic (1.05e-2)" OLFML2B DKFZP586L151 ENSG00000162745 "Olfactomedin like 2B" Q68BL8 1 161983192-162023869 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 46.7" "Cell type enhanced" "Detected in many" "Early spermatids: 155.8;Fibroblasts: 25.6;Hofbauer cells: 36.2;Kupffer cells: 28.0;Macrophages: 27.3;Peritubular cells: 27.9;Smooth muscle cells: 45.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 6.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 11 "monocytes: 6.7" "Cancer enhanced" "Detected in many" "Rhabdoid: 80.6;Sarcoma: 41.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Group enriched" "Detected in all" 4 "hippocampal formation: 41.0;white matter: 11.9" "Low region specificity" "Detected in all" "HPA054136, HPA062739" Approved Approved Cytosol "Secreted - unknown location" "No annotated function" NA NA 12000 "Cluster 40: Monocytes - Innate immune response" "Cluster 58: Placenta - Pregnancy" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" Cytosol "HPA054136: AB_2682397, HPA062739: AB_2684858" "unprognostic (2.97e-2)" "unprognostic (1.79e-1)" "unprognostic (8.91e-2)" "unprognostic (1.05e-1)" "unprognostic (6.01e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (5.97e-3)" "unprognostic (7.32e-2)" "unprognostic (7.68e-3)" "unprognostic (1.16e-1)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.01e-12)" "unprognostic (1.64e-3)" "unprognostic (2.11e-2)" "unprognostic (4.53e-3)" "unprognostic (1.97e-2)" OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 245.2" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 134.9;Fibroblasts: 229.9;Leydig cells: 76.6;Ovarian stromal cells: 170.1;Smooth muscle cells: 71.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cancer enhanced" "Detected in many" "Bone cancer: 137.5;testis cancer: 132.0" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 3000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" OLR1 "CLEC8A, LOX-1, SCARE1" ENSG00000173391 "Oxidized low density lipoprotein receptor 1" P78380 12 10158301-10172138 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 97.0;placenta: 110.6" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 379.7;Hofbauer cells: 215.6;Langerhans cells: 114.6;Macrophages: 201.5;monocytes: 313.5;Syncytiotrophoblasts: 410.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "cervical cancer: 116.7;head and neck cancer: 80.2" "Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050798 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" Receptor NA NA 1060000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 2 "Nucleoplasm, Plasma membrane" Vesicles "HPA050798: AB_2756318" "unprognostic (2.30e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (6.34e-2)" "unprognostic (6.07e-3)" "unprognostic (5.40e-2)" "unprognostic (2.64e-1)" "unprognostic (1.97e-2)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.94e-3)" "unprognostic (3.47e-2)" "unprognostic (1.48e-2)" "unprognostic (1.42e-1)" OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 86.6;Leydig cells: 129.3;Mesothelial cells: 46.3;Ovarian stromal cells: 79.5;Peritubular cells: 156.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" "Cell adhesion" NA NA 21000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" OMG OMGP ENSG00000126861 "Oligodendrocyte myelin glycoprotein" P23515 17 31272013-31297539 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 83.2" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 73.5;Ciliated cells: 373.1;Ionocytes: 240.4;Muller glia cells: 67.5;Oligodendrocyte precursor cells: 73.6;Oligodendrocytes: 94.8" "Group enriched" "Detected in some" 7 "endometrial cancer: 3.5;glioma: 9.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008206, HPA012693" Enhanced "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" "HPA008206: AB_1854240, HPA012693: AB_1854239" "unprognostic (8.05e-4)" "unprognostic (2.11e-2)" "unprognostic (1.27e-1)" "unprognostic (3.03e-3)" "unprognostic (1.85e-1)" "unprognostic (4.16e-2)" "unprognostic (1.63e-1)" "unprognostic (3.81e-2)" "unprognostic (9.54e-2)" "unprognostic (8.60e-2)" "unprognostic (7.03e-2)" "unprognostic (1.52e-1)" "unprognostic (3.96e-13)" "unprognostic (7.80e-3)" "unprognostic (6.00e-2)" "unprognostic (3.24e-1)" "unprognostic (2.42e-2)" OOSP2 "FLJ36198, OOSP2A, PLAC1L, TMEM122" ENSG00000149507 "Oocyte secreted protein 2" Q86WS3 11 60040409-60048044 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 17.4" "Cell type enriched" "Detected in some" 49 "Oocytes: 539.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA050914 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 20: Testis - Spermatogenesis" "Cluster 65: Non-specific - Unknown function" "Cluster 44: Oocytes - Unknown function" 2 "HPA050914: AB_2681271" OOSP3 ENSG00000285231 "Oocyte secreted protein family member 3" A0A2R8YFM6 11 59878782-59896483 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 33 "basophil: 5.4" "Lineage enriched" "Detected in single" 54 "granulocytes: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted - unknown location" "No annotated function" NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" OOSP4A ENSG00000285010 "Oocyte secreted protein family member 4A" A0A2R8YFL7 11 59964033-59970343 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 7.5" "Lineage enriched" "Detected in single" 23 "granulocytes: 7.5" "Cancer enriched" "Detected in single" 11 "Leukemia: 1.0" "Secreted - unknown location" "No annotated function" NA NA "Cluster 47: Leukemia - Hemostasis" OOSP4B ENSG00000255393 "Oocyte secreted protein family member 4B" A0A2R8Y4Y8 11 59978020-60031077 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 65 "Oocytes: 25.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" "No annotated function" NA NA "Cluster 44: Oocytes - Unknown function" OPCML "IGLON1, OBCAM, OPCM" ENSG00000183715 "Opioid binding protein/cell adhesion molecule like" Q14982 11 132414977-133532501 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 36.6;parathyroid gland: 10.0;retina: 11.0" "Group enriched" "Detected in some" 34 "Excitatory neurons: 2050.4;Inhibitory neurons: 1824.2;Oligodendrocyte precursor cells: 2977.6" "Cancer enriched" "Detected in some" 4 "glioma: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.6;thyroid cancer: 1.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "Cell adhesion" NA NA 7100000 "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 3 "unprognostic (1.59e-1)" "unprognostic (2.26e-2)" "unprognostic (3.70e-2)" "unprognostic (3.31e-4)" "unprognostic (8.23e-2)" "unprognostic (3.53e-2)" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (8.46e-3)" "unprognostic (2.59e-2)" "unprognostic (2.80e-1)" "unprognostic (4.73e-2)" "unprognostic (1.11e-2)" "unprognostic (1.13e-2)" "unprognostic (1.76e-1)" "unprognostic (9.71e-2)" "unprognostic (2.19e-1)" OPRPN "BPLP, PRL1, PROL1" ENSG00000171199 "Opiorphin prepropeptide" Q99935 4 70397931-70410195 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 142.3" "Group enriched" "Detected in some" 7 "Breast glandular cells: 11.0;Serous glandular cells: 21.9" "Group enriched" "Detected in some" 5 "breast cancer: 7.4;liver cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells, Testis - Late spermatids" HPA065711 Approved "Secreted in other tissues" "Enzyme inhibitor" NA NA 63000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA065711: AB_2685541" "unprognostic (3.11e-3)" "unprognostic (2.22e-2)" OPTC ENSG00000188770 Opticin Q9UBM4 1 203494153-203508949 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 1.4;Spermatocytes: 1.5" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034951, HPA034952" Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA034951: AB_10669852, HPA034952: AB_2674379" "unprognostic (3.29e-1)" "unprognostic (1.56e-1)" "unprognostic (7.69e-2)" "unprognostic (3.19e-2)" "unprognostic (1.70e-3)" "unprognostic (8.24e-2)" "unprognostic (3.65e-2)" ORM1 ENSG00000229314 "Orosomucoid 1" P02763 9 114323098-114326479 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 177 "liver: 41892.9" "Cell type enriched" "Detected in some" 53 "Hepatocytes: 54806.5" "Cancer enriched" "Detected in many" 16 "liver cancer: 2506.9" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 47 "neutrophil: 201.8" "Lineage enriched" "Detected in many" 47 "granulocytes: 201.8" "Cancer enriched" "Detected in many" 4 "liver cancer: 243.4" "Liver - Hepatocytes, Lung - Neutrophil_2" "CAB006265, HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Acute phase" NA NA 945000000000 61000000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 31: Liver - Plasma proteins" "Cluster 54: Immune cells - T cell receptor" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 Vesicles "Golgi apparatus" "CAB006265: AB_425575, HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (3.85e-1)" "unprognostic (2.12e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (1.16e-1)" "unprognostic (4.85e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (2.35e-4)" "unprognostic (2.10e-1)" "unprognostic (4.38e-2)" "unprognostic (9.32e-3)" "unprognostic (4.51e-2)" ORM2 "AGP-B, AGP-B', AGP2" ENSG00000228278 "Orosomucoid 2" P19652 9 114329869-114333251 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 297 "liver: 8652.9" "Cell type enriched" "Detected in some" 44 "Hepatocytes: 9678.3" "Cancer enriched" "Detected in many" 34 "liver cancer: 873.1" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 39 "neutrophil: 13.2" "Lineage enriched" "Detected in single" 39 "granulocytes: 13.2" "Cancer enriched" "Detected in some" 27 "liver cancer: 95.6" "Liver - Hepatocytes, Testis - Late spermatids" "HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Acute phase" NA NA 422000000 41000000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 31: Liver - Plasma proteins" "Cluster 33: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" Vesicles "Golgi apparatus" "HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (6.77e-2)" "unprognostic (8.00e-2)" "unprognostic (1.19e-1)" "unprognostic (4.44e-3)" "unprognostic (1.18e-1)" "unprognostic (5.61e-2)" "unprognostic (5.66e-2)" "unprognostic (9.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (5.76e-2)" "prognostic unfavorable (1.23e-9)" "unprognostic (3.23e-1)" "unprognostic (6.80e-2)" "unprognostic (7.62e-2)" "unprognostic (9.15e-4)" OS9 "ERLEC2, OS-9" ENSG00000135506 "OS9 endoplasmic reticulum lectin" Q13438 12 57693841-57728342 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011518, HPA013694" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 10000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" 5 "Endoplasmic reticulum" "CAB011518: AB_776918, HPA013694: AB_1854812" "unprognostic (1.67e-2)" "unprognostic (4.20e-1)" "unprognostic (3.93e-2)" "unprognostic (1.50e-1)" "unprognostic (9.79e-3)" "unprognostic (1.32e-3)" "unprognostic (4.78e-2)" "unprognostic (8.54e-2)" "unprognostic (2.67e-1)" "unprognostic (1.64e-1)" "unprognostic (5.67e-3)" "unprognostic (2.23e-1)" "unprognostic (1.83e-2)" "unprognostic (2.78e-1)" "unprognostic (1.67e-2)" "unprognostic (4.81e-2)" "unprognostic (2.21e-2)" OSCAR ENSG00000170909 "Osteoclast associated Ig-like receptor" Q8IYS5 19 54094668-54102692 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 13.2;lung: 27.5;lymphoid tissue: 29.0" "Group enriched" "Detected in some" 5 "Hofbauer cells: 49.4;Kupffer cells: 23.7;Langerhans cells: 16.0;Macrophages: 41.3;monocytes: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 35 "classical monocyte: 41.9;eosinophil: 26.4;intermediate monocyte: 28.1;myeloid DC: 19.6;neutrophil: 38.8;non-classical monocyte: 26.7" "Group enriched" "Detected in many" 77 "dendritic cells: 19.6;granulocytes: 38.8;monocytes: 41.9" "Group enriched" "Detected in some" 4 "Leukemia: 8.2;ovarian cancer: 2.5;thyroid cancer: 5.9" "Adipose subcutaneous - Macrophages, Kidney - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073996 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 84000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA073996: " "unprognostic (9.09e-2)" "unprognostic (6.79e-3)" "unprognostic (8.47e-3)" "unprognostic (2.14e-1)" "unprognostic (2.12e-2)" "unprognostic (9.04e-2)" "unprognostic (1.39e-1)" "unprognostic (3.86e-1)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.05e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.71e-5)" "unprognostic (1.84e-1)" "unprognostic (2.88e-2)" "unprognostic (9.69e-2)" "unprognostic (4.28e-2)" OSM MGC20461 ENSG00000099985 "Oncostatin M" P13725 22 30262829-30266851 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Cytokine, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 116.9" "Cell type enhanced" "Detected in some" "granulocytes: 38.6;Hofbauer cells: 159.6;Macrophages: 52.3;monocytes: 33.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 65.5;neutrophil: 35.0" "Lineage enriched" "Detected in many" 10 "granulocytes: 65.5" "Cancer enhanced" "Detected in some" "Leukemia: 11.1;lymphoma: 6.2" "Colon - Neutrophils" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "spinal cord: 3.3" "Secreted to blood" Cytokine NA NA 39700 "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 1 "unprognostic (5.15e-2)" "unprognostic (8.80e-3)" "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (7.37e-2)" "unprognostic (2.61e-2)" "unprognostic (6.78e-2)" "unprognostic (3.77e-2)" "unprognostic (2.81e-2)" "unprognostic (4.60e-2)" "unprognostic (1.58e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.00e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-1)" "unprognostic (1.82e-1)" OSMR "OSMRB, OSMRbeta" ENSG00000145623 "Oncostatin M receptor" Q99650 5 38845858-38945596 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 113.9;Alveolar cells type 2: 68.3;Endothelial cells: 68.6;Mucus glandular cells: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017278 Approved Approved Nucleoli "Intracellular and membrane" Receptor NA NA 51000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 9 Nucleoli "HPA017278: AB_1854818" "unprognostic (6.34e-3)" "prognostic unfavorable (4.87e-4)" "unprognostic (2.58e-1)" "unprognostic (2.11e-1)" "unprognostic (2.18e-3)" "unprognostic (1.13e-1)" "unprognostic (8.00e-3)" "unprognostic (5.70e-2)" "unprognostic (1.79e-3)" "unprognostic (1.72e-3)" "unprognostic (1.60e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.96e-6)" "unprognostic (1.88e-2)" "unprognostic (1.49e-2)" "unprognostic (4.43e-1)" "unprognostic (1.75e-2)" OSTN ENSG00000188729 Osteocrin P61366 3 191199241-191265615 "Predicted secreted proteins" Differentiation "Developmental protein, Hormone" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9" "Group enriched" "Detected in some" 4 "Early spermatids: 4.4;Inhibitory neurons: 5.7;Oligodendrocyte precursor cells: 2.4;Skeletal myocytes: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 29 "Rhabdoid: 37.1" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in some" "CAB024997, CAB025649, HPA030878" Uncertain "Secreted in other tissues" Hormone NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 5: Rhabdoid - Unknown function" "Cluster 8: Neurons - Neuronal signaling" "CAB024997: , CAB025649: , HPA030878: AB_2673642" "unprognostic (2.35e-2)" "unprognostic (9.12e-2)" "unprognostic (6.30e-2)" "unprognostic (2.34e-1)" "unprognostic (2.51e-1)" "unprognostic (3.01e-2)" "unprognostic (2.52e-1)" "unprognostic (8.11e-3)" "unprognostic (2.90e-1)" "unprognostic (1.45e-1)" OTOA "CT108, DFNB22" ENSG00000155719 Otoancorin Q7RTW8 16 21663968-21761935 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "lymphoid tissue: 2.0;testis: 3.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 43.6;Kupffer cells: 27.8;Late spermatids: 12.9;Macrophages: 9.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 10 "dendritic cells: 1.3" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA041405 Enhanced "Secreted in other tissues" Other NA NA 51000 "Cluster 44: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA041405: AB_10796344" "unprognostic (7.96e-2)" "unprognostic (2.44e-4)" "unprognostic (1.66e-2)" "unprognostic (9.69e-2)" "unprognostic (2.15e-1)" "unprognostic (1.35e-1)" "unprognostic (5.11e-1)" "unprognostic (4.71e-2)" "unprognostic (7.92e-2)" "unprognostic (3.58e-1)" "unprognostic (1.08e-2)" "unprognostic (2.15e-1)" "unprognostic (1.08e-4)" "unprognostic (1.83e-1)" "unprognostic (1.20e-1)" "unprognostic (2.24e-1)" "unprognostic (2.18e-2)" OTOG "FLJ46346, mlemp, OTGN" ENSG00000188162 Otogelin Q6ZRI0 11 17547259-17647150 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pituitary gland: 1.3" "Cell type enriched" "Detected in some" 4 "Late spermatids: 30.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 63: Late spermatids - Spermatogenesis" "unprognostic (1.25e-2)" "unprognostic (1.19e-1)" "unprognostic (6.95e-3)" "unprognostic (1.85e-6)" "unprognostic (1.89e-1)" "unprognostic (3.60e-1)" "unprognostic (5.14e-5)" "unprognostic (1.78e-1)" "unprognostic (8.97e-2)" "unprognostic (1.57e-2)" "unprognostic (4.72e-5)" "unprognostic (5.55e-2)" "unprognostic (1.48e-1)" OTOGL "C12orf64, FLJ90579" ENSG00000165899 "Otogelin like" Q3ZCN5 12 80099537-80380880 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 1.8;kidney: 5.0" "Group enriched" "Detected in some" 5 "Excitatory neurons: 49.6;Oligodendrocyte precursor cells: 39.6" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.5" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "basal ganglia: 5.5" "HPA040364, HPA053392" Uncertain Approved Cytosol "Secreted in other tissues" "No annotated function" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 1 Cytosol "HPA040364: AB_10795365, HPA053392: AB_2682135" "unprognostic (2.43e-1)" "unprognostic (2.78e-2)" "unprognostic (2.55e-2)" "unprognostic (1.50e-1)" "unprognostic (5.99e-2)" "unprognostic (3.10e-1)" "unprognostic (3.34e-3)" "unprognostic (4.76e-2)" "unprognostic (2.72e-2)" "unprognostic (4.52e-2)" "unprognostic (2.79e-2)" "unprognostic (1.57e-1)" "unprognostic (1.95e-5)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (2.79e-2)" "unprognostic (2.04e-2)" OTOL1 "C1QTNF15, C1QTNF16" ENSG00000182447 "Otolin 1" A6NHN0 3 161496808-161503942 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "cervical cancer: 8.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA041030 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "HPA041030: AB_10795000" OTOR "FDP, MIAL, MIAL1" ENSG00000125879 Otoraplin Q9NRC9 20 16748358-16770062 "Predicted secreted proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "breast cancer: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024335 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "HPA024335: AB_1854838" "unprognostic (8.50e-3)" "unprognostic (9.56e-2)" "unprognostic (2.34e-1)" "unprognostic (1.81e-1)" "unprognostic (1.72e-1)" OTOS OTOSP ENSG00000178602 Otospiralin Q8NHW6 2 240139026-240144562 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 100.3;thyroid gland: 42.4" "Cell type enhanced" "Detected in some" "Astrocytes: 1.2;Horizontal cells: 1.3" "Cancer enriched" "Detected in some" 4 "thyroid cancer: 28.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 59 "thyroid cancer: 12.8" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Low region specificity" "Detected in many" "Secreted in other tissues" "No annotated function" NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 47: Astrocytes - Unknown function" 3 "unprognostic (8.52e-2)" "unprognostic (1.73e-1)" "unprognostic (9.01e-3)" "unprognostic (1.35e-1)" "unprognostic (2.72e-1)" "unprognostic (3.27e-3)" OVCH1 OVCH ENSG00000187950 "Ovochymase 1" Q7RTY7 12 29412474-29497686 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 1.5;testis: 1.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 13.9;Inhibitory neurons: 14.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Prostate - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Secreted in other tissues" Enzyme NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 8: Neurons - Neuronal signaling" "unprognostic (3.32e-1)" "unprognostic (2.20e-1)" "unprognostic (2.03e-1)" "unprognostic (1.56e-5)" "unprognostic (1.68e-1)" "unprognostic (1.58e-1)" "unprognostic (4.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.36e-1)" "unprognostic (5.48e-2)" "unprognostic (5.59e-3)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" OVCH2 OVTN ENSG00000183378 "Ovochymase 2" 11 7689437-7706477 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 15 "epididymis: 183.4;retina: 89.4" "Group enriched" "Detected in some" 7 "Collecting duct cells: 7.8;Rod photoreceptor cells: 18.8" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.6;testis cancer: 2.9" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 66: Photoreceptor cells - Visual perception" "unprognostic (1.59e-2)" "unprognostic (3.74e-1)" "unprognostic (8.03e-2)" "unprognostic (9.77e-2)" "unprognostic (1.85e-1)" "unprognostic (1.70e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.84e-2)" "unprognostic (3.06e-1)" "unprognostic (9.27e-2)" "unprognostic (7.65e-2)" "unprognostic (1.22e-2)" OVGP1 "CHIT5, MUC9" ENSG00000085465 "Oviductal glycoprotein 1" Q12889 1 111414319-111427735 "Plasma proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 134 "fallopian tube: 2005.5" "Cell type enriched" "Detected in many" 34 "Secretory cells: 1748.2" "Group enriched" "Detected in many" 13 "endometrial cancer: 58.7;ovarian cancer: 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Early spermatids" "Region enhanced" "Detected in many" "cerebellum: 5.9" "Low region specificity" "Detected in some" "HPA031666, HPA062205" Enhanced Supported Vesicles,Microtubules "Secreted in female reproductive system" Other NA NA "Cluster 59: Fallopian tube - Tissue development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 37: Glandular & Luminal cells - Unknown function" Vesicles Microtubules "HPA031666: , HPA062205: AB_2684710" "unprognostic (1.52e-1)" "unprognostic (2.06e-2)" "unprognostic (3.35e-2)" "prognostic favorable (1.36e-4)" "unprognostic (8.39e-2)" "unprognostic (3.58e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-2)" "unprognostic (5.44e-2)" "unprognostic (3.82e-2)" "unprognostic (7.68e-3)" "unprognostic (2.58e-1)" "unprognostic (5.35e-3)" "unprognostic (2.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.86e-3)" "prognostic favorable (3.93e-5)" OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 237.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 305.6;Distal tubular cells: 224.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria "Intracellular and membrane" Enzyme NA NA 440000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 30: Heart muscle - Heart development" "Cluster 14: Neurons - Synaptic function" "Cluster 29: Non-specific - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" Mitochondria "HPA012047: AB_1854857, HPA061425: AB_2684515" "unprognostic (4.26e-2)" "unprognostic (2.10e-2)" "unprognostic (2.89e-2)" "unprognostic (1.51e-1)" "unprognostic (5.51e-2)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (7.42e-3)" "unprognostic (1.74e-3)" "unprognostic (1.67e-1)" "unprognostic (2.80e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.86e-8)" "unprognostic (2.66e-2)" "unprognostic (9.99e-2)" "unprognostic (5.86e-3)" "unprognostic (2.28e-3)" OXNAD1 MGC15763 ENSG00000154814 "Oxidoreductase NAD binding domain containing 1" Q96HP4 3 16265160-16350299 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 64.8;Inhibitory neurons: 60.3;T-cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 81.2" "Lineage enriched" "Detected in all" 4 "T-cells: 81.2" "Low cancer specificity" "Detected in all" "Colon - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036830, HPA059160" Approved Approved Nucleoplasm "Intracellular and membrane" Enzyme NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 53: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 Nucleoplasm "HPA036830: AB_2675338, HPA059160: AB_2683936" "unprognostic (4.49e-2)" "unprognostic (7.41e-3)" "unprognostic (2.71e-3)" "unprognostic (2.38e-3)" "unprognostic (4.65e-2)" "unprognostic (3.23e-2)" "unprognostic (1.46e-1)" "unprognostic (2.31e-2)" "unprognostic (1.23e-2)" "unprognostic (8.05e-2)" "unprognostic (1.46e-1)" "unprognostic (8.08e-2)" "prognostic favorable (1.00e-7)" "unprognostic (2.22e-2)" "unprognostic (1.03e-1)" "unprognostic (6.95e-3)" "prognostic favorable (7.63e-4)" OXT "OT, OT-NPI, OXT-NPI" ENSG00000101405 "Oxytocin/neurophysin I prepropeptide" P01178 20 3071620-3072517 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 143 "brain: 2690.9" "Group enriched" "Detected in some" 4 "Hepatocytes: 42.3;Late spermatids: 76.5;Oocytes: 133.8;Proximal tubular cells: 41.6" "Cancer enriched" "Detected in some" 5 "testis cancer: 12.1" "Region enriched" "Detected in many" 144 "hypothalamus: 2524.3" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 4 "Gastric cancer: 1.5" "Kidney - Proximal tubular cells" "Region enriched" "Detected in many" 6 "hypothalamus: 179.4" "Group enriched" "Detected in some" 892 "basal ganglia: 866.7;hypothalamus: 2049.5" HPA071892 Supported Supported "Secreted to blood" Hormone NA NA 1500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 44: Oocytes - Unknown function" 1 "HPA071892: AB_2732190" "unprognostic (7.45e-3)" "unprognostic (1.99e-2)" "unprognostic (2.66e-2)" "unprognostic (2.28e-1)" "unprognostic (2.62e-1)" "unprognostic (3.82e-2)" "unprognostic (8.22e-2)" "unprognostic (8.36e-2)" "unprognostic (6.02e-2)" "unprognostic (3.05e-2)" "unprognostic (6.65e-2)" "unprognostic (6.18e-1)" "unprognostic (3.81e-1)" "unprognostic (3.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" P3H1 "GROS1, LEPRE1, LEPRECAN, MGC117314" ENSG00000117385 "Prolyl 3-hydroxylase 1" Q32P28 1 42746335-42767084 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.5;Extravillous trophoblasts: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012113, HPA016980" Approved Approved Nucleoli,Vesicles "Intracellular and membrane" Enzyme NA NA 18000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Connective tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" Vesicles Nucleoli "HPA012113: AB_2668626, HPA016980: AB_2669498" "unprognostic (3.24e-1)" "unprognostic (1.04e-1)" "unprognostic (9.37e-2)" "unprognostic (4.57e-1)" "unprognostic (2.03e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.95e-7)" "unprognostic (5.41e-2)" "unprognostic (2.70e-3)" "unprognostic (9.16e-2)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" "unprognostic (2.67e-2)" "unprognostic (1.60e-3)" P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 72.1;Excitatory neurons: 53.7;Inhibitory neurons: 57.9;Microglial cells: 87.7;Prostatic glandular cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in single" 112 "dendritic cells: 28.9" "Cancer enhanced" "Detected in all" "Kidney cancer: 132.1" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 47: Spleen - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Vesicles, Cytosol" "HPA007890: AB_1852796, HPA013355: AB_1852798, HPA013611: " "unprognostic (4.90e-2)" "unprognostic (1.57e-1)" "unprognostic (3.76e-1)" "unprognostic (4.32e-3)" "unprognostic (1.97e-2)" "unprognostic (7.75e-2)" "unprognostic (9.68e-2)" "unprognostic (2.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-2)" P3H3 "GRCB, HSU47926, LEPREL2" ENSG00000110811 "Prolyl 3-hydroxylase 3" Q8IVL6 12 6828407-6839847 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 44.3;Cone photoreceptor cells: 164.8;Leydig cells: 49.6;Peritubular cells: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043695 Approved Approved "Nucleoli,Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 740000 "Cluster 64: Neuronal - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane, Cytosol" Nucleoli "HPA043695: AB_10797146" "unprognostic (2.54e-1)" "unprognostic (6.66e-2)" "unprognostic (1.14e-1)" "unprognostic (3.34e-2)" "unprognostic (5.76e-2)" "unprognostic (6.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.92e-1)" "unprognostic (6.90e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.64e-4)" "unprognostic (2.58e-2)" "unprognostic (9.67e-2)" "unprognostic (2.27e-1)" "unprognostic (7.77e-3)" P3H4 "LEPREL4, NO55, SC65" ENSG00000141696 "Prolyl 3-hydroxylase family member 4 (inactive)" Q92791 17 41801947-41812604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 3.9;MAIT T-cell: 5.0;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.6;naive CD4 T-cell: 2.9;naive CD8 T-cell: 3.9;NK-cell: 8.5" "Group enriched" "Detected in many" 11 "NK-cells: 8.5;T-cells: 5.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022520 Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" "No annotated function" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Endoplasmic reticulum, Vesicles" "HPA022520: " "unprognostic (9.11e-2)" "unprognostic (3.72e-3)" "unprognostic (3.66e-2)" "unprognostic (3.72e-2)" "unprognostic (8.69e-3)" "unprognostic (4.32e-2)" "unprognostic (2.16e-3)" "unprognostic (1.94e-1)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (4.03e-2)" "prognostic unfavorable (4.48e-6)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (8.96e-2)" "unprognostic (1.96e-3)" P4HA1 "C-P4Halpha(I), P4HA" ENSG00000122884 "Prolyl 4-hydroxylase subunit alpha 1" P13674 10 73007217-73096974 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007599, HPA026593" Enhanced Supported "Endoplasmic reticulum,Vesicles,Mitochondria" "Intracellular and membrane" Enzyme Yes No 60000 "Cluster 40: Monocytes - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Endoplasmic reticulum" "Vesicles, Mitochondria" "HPA007599: AB_1854891, HPA026593: AB_1854892" "prognostic unfavorable (9.01e-4)" "prognostic unfavorable (3.19e-5)" "unprognostic (2.76e-3)" "unprognostic (3.04e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (2.30e-1)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.28e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.15e-2)" "prognostic unfavorable (9.40e-9)" "unprognostic (3.14e-1)" "unprognostic (4.22e-2)" "unprognostic (1.02e-2)" "unprognostic (5.75e-2)" P4HA2 "C-P4Halpha(II), lncRNA-PE" ENSG00000072682 "Prolyl 4-hydroxylase subunit alpha 2" O15460 5 132190147-132295315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 128.3;Basal respiratory cells: 103.4;Endometrial stromal cells: 102.3;Pancreatic endocrine cells: 107.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016997, HPA027824, CAB062557" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme No No 13000 "Cluster 35: Neutrophils - Protein binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 3 "Endoplasmic reticulum, Vesicles" "CAB062557: AB_2665641, HPA016997: AB_2669501, HPA027824: AB_2672402" "unprognostic (1.30e-3)" "prognostic unfavorable (1.24e-5)" "unprognostic (2.56e-3)" "unprognostic (1.28e-3)" "unprognostic (2.08e-3)" "unprognostic (1.62e-3)" "unprognostic (1.16e-3)" "unprognostic (1.93e-3)" "unprognostic (2.83e-2)" "unprognostic (1.92e-1)" "unprognostic (8.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (2.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.12e-4)" P4HA3 C-P4Halpha(III) ENSG00000149380 "Prolyl 4-hydroxylase subunit alpha 3" Q7Z4N8 11 74235801-74311640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 10.1" "Cell type enhanced" "Detected in many" "Early spermatids: 29.2;Granulosa cells: 12.0;Lymphatic endothelial cells: 12.4;Rod photoreceptor cells: 12.2;Spermatocytes: 16.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 7.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA007897 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 39 "HPA007897: AB_2156427" "unprognostic (2.74e-2)" "unprognostic (1.37e-4)" "unprognostic (1.31e-3)" "unprognostic (3.19e-2)" "unprognostic (2.54e-4)" "unprognostic (9.65e-3)" "unprognostic (4.34e-2)" "unprognostic (3.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.21e-3)" "unprognostic (1.38e-2)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.34e-9)" "unprognostic (1.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.83e-4)" P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860856 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1810.7;pancreas: 2376.2" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1511.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme No No 110000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 12: Non-specific - Vasculature" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 40 "Endoplasmic reticulum" "CAB012463: , HPA018884: AB_1854896" "unprognostic (9.47e-3)" "unprognostic (1.09e-2)" "unprognostic (2.99e-2)" "unprognostic (7.14e-3)" "unprognostic (7.75e-3)" "unprognostic (1.05e-2)" "unprognostic (1.30e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (4.73e-3)" "unprognostic (1.43e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (2.30e-11)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (4.99e-3)" "unprognostic (3.19e-3)" PAEP "GD, GdA, GdF, GdS, MGC138509, MGC142288, PAEG, PEP, PP14" ENSG00000122133 "Progestagen associated endometrial protein" P09466 9 135561756-135566955 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 91.3;endometrium 1: 247.4" "Cell type enriched" "Detected in some" 14 "Glandular and luminal cells: 15450.1" "Cancer enriched" "Detected in many" 8 "melanoma: 275.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.1;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.1" "Group enriched" "Detected in many" 6 "skin cancer: 32.2;thyroid cancer: 74.6" "Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016762, HPA020108, HPA029473" Enhanced "Secreted in female reproductive system" "No annotated function" NA NA 120000 "Cluster 20: Non-specific - DNA binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 48: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 37: Glandular & Luminal cells - Unknown function" 12 "CAB016762: , HPA020108: AB_1855595, HPA029473: AB_10610147" "unprognostic (3.39e-2)" "unprognostic (8.47e-3)" "unprognostic (6.84e-2)" "unprognostic (3.46e-2)" "unprognostic (3.20e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (1.27e-2)" "unprognostic (1.72e-1)" "unprognostic (3.95e-3)" "unprognostic (1.93e-3)" "prognostic unfavorable (0.00e+0)" "prognostic unfavorable (5.46e-4)" "unprognostic (4.24e-1)" "unprognostic (4.98e-2)" PAM "PAL, PHM" ENSG00000145730 "Peptidylglycine alpha-amidating monooxygenase" P19021 5 102753981-103029730 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" "Lyase, Monooxygenase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1508.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1260.5;Excitatory neurons: 221.7;Inhibitory neurons: 468.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026119, HPA042260" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted in other tissues" Enzyme NA NA 98000000 "Cluster 1: T-cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Cardiomyocytes - Muscle contraction" "Golgi apparatus, Cytosol" "CAB026119: , HPA042260: AB_2677919" "unprognostic (4.30e-3)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "prognostic favorable (1.63e-4)" "unprognostic (4.23e-2)" "unprognostic (6.30e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (7.58e-2)" "unprognostic (6.62e-2)" "unprognostic (2.71e-1)" "unprognostic (9.91e-2)" "unprognostic (3.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (9.79e-2)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" PAMR1 "DKFZP586H2123, RAMP" ENSG00000149090 "Peptidase domain containing associated with muscle regeneration 1" Q6UXH9 11 35431823-35530300 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 13 "Astrocytes: 360.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 11.3;testis cancer: 13.1" "Breast - Breast myoepithelial cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted - unknown location" Other NA NA 5600000 "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 47: Astrocytes - Unknown function" "unprognostic (3.38e-1)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-3)" "unprognostic (6.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.07e-2)" "unprognostic (6.92e-2)" "unprognostic (3.32e-2)" "unprognostic (4.07e-2)" "unprognostic (1.91e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.08e-5)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.08e-1)" "unprognostic (9.98e-2)" "unprognostic (8.25e-2)" PAPLN MGC50452 ENSG00000100767 "Papilin, proteoglycan like sulfated glycoprotein" O95428 14 73237497-73274640 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 113.6;Endometrial stromal cells: 34.3;Leydig cells: 34.8;Peritubular cells: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "neutrophil: 2.5;plasmacytoid DC: 5.5" "Group enriched" "Detected in many" 7 "dendritic cells: 5.5;granulocytes: 2.5" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048682 Uncertain "Secreted - unknown location" "Enzyme inhibitor" NA NA 76000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 51: Thyroid gland - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Astrocytes - Unknown function" "HPA048682: AB_2680492" "unprognostic (1.97e-3)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (3.56e-3)" "unprognostic (7.42e-2)" "unprognostic (7.91e-3)" "unprognostic (2.01e-2)" "unprognostic (2.46e-3)" "unprognostic (9.13e-3)" "unprognostic (3.69e-2)" "unprognostic (1.41e-1)" "unprognostic (4.87e-2)" "unprognostic (1.89e-2)" "unprognostic (2.14e-2)" "unprognostic (3.05e-3)" "unprognostic (2.69e-2)" "unprognostic (5.58e-2)" PAPPA "ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1" ENSG00000182752 "Pappalysin 1" Q13219 9 116153791-116402321 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "placenta: 70.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 61.8;Collecting duct cells: 134.2;Endometrial stromal cells: 109.5;Horizontal cells: 57.9;Mesothelial cells: 93.4;Proximal tubular cells: 53.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 33.8" "Colon - Enteric glia cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA001667, CAB016724" Enhanced "Secreted in female reproductive system" Enzyme NA NA 78000000 "Cluster 58: Placenta - Pregnancy" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 1 "CAB016724: , HPA001667: AB_1854960" "unprognostic (3.25e-1)" "unprognostic (6.18e-6)" "unprognostic (2.47e-1)" "unprognostic (6.49e-2)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (5.42e-3)" "unprognostic (5.44e-2)" "unprognostic (3.87e-2)" "unprognostic (6.87e-3)" "unprognostic (8.25e-2)" "unprognostic (8.00e-3)" "unprognostic (2.37e-3)" "unprognostic (2.48e-1)" "unprognostic (4.01e-1)" "unprognostic (1.02e-3)" PAPPA2 "PAPP-A2, PAPPE, PLAC3" ENSG00000116183 "Pappalysin 2" Q9BXP8 1 176463171-176845601 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 54.9" "Cell type enhanced" "Detected in some" "Astrocytes: 24.8;Enteroendocrine cells: 59.0;Extravillous trophoblasts: 98.0;Muller glia cells: 32.4;Oligodendrocytes: 35.1;Syncytiotrophoblasts: 76.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Spermatogonia, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 8.1" "HPA018412, HPA018430" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted in female reproductive system" Enzyme NA NA 2000000 "Cluster 58: Placenta - Pregnancy" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" "Endoplasmic reticulum, Vesicles" "HPA018412: AB_1854962, HPA018430: AB_1854961" "unprognostic (2.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-2)" "unprognostic (9.04e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (3.54e-2)" "unprognostic (1.29e-2)" "unprognostic (4.39e-2)" "unprognostic (2.85e-2)" "unprognostic (1.52e-4)" "unprognostic (1.85e-1)" "unprognostic (8.18e-4)" "unprognostic (4.35e-2)" PARP15 "ARTD7, BAL3, FLJ40597, pART7" ENSG00000173200 "Poly(ADP-ribose) polymerase family member 15" Q460N3 3 122577628-122639047 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 22.4;intestine: 41.0;lymphoid tissue: 65.6" "Cell type enhanced" "Detected in some" "B-cells: 84.8;granulocytes: 14.1;NK-cells: 41.1;T-cells: 24.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Leukemia: 17.5;lymphoma: 15.2" "Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Intracellular and membrane" Transcription NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" "unprognostic (8.19e-3)" "unprognostic (2.88e-3)" "unprognostic (1.12e-1)" "unprognostic (1.18e-3)" "unprognostic (1.22e-1)" "unprognostic (9.01e-5)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (3.91e-2)" "unprognostic (5.40e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (9.24e-7)" "unprognostic (9.03e-2)" "unprognostic (2.07e-2)" "unprognostic (1.52e-1)" "unprognostic (1.22e-2)" PATE1 PATE ENSG00000171053 "Prostate and testis expressed 1" Q8WXA2 11 125746279-125749867 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "epididymis: 1824.1" "Cell type enriched" "Detected in some" 54 "Basal prostatic cells: 215.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076587 Approved "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 3 "HPA076587: AB_2732316" PATE2 "C11orf38, LVLF3112, PATE-M, UNQ3112" ENSG00000196844 "Prostate and testis expressed 2" Q6UY27 11 125776113-125778828 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "epididymis: 439.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 11.7;Early spermatids: 3.9;Excitatory neurons: 2.6;Inhibitory neurons: 3.0;Late spermatids: 14.7;Oligodendrocyte precursor cells: 2.8;Spermatocytes: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;prostate cancer: 1.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 3: Basal prostatic cells - Lipid metabolism" "unprognostic (3.28e-1)" "unprognostic (7.26e-2)" "unprognostic (2.95e-1)" "unprognostic (1.18e-2)" "unprognostic (2.63e-1)" "unprognostic (6.84e-3)" "unprognostic (1.55e-2)" "unprognostic (5.08e-1)" "unprognostic (2.55e-1)" PATE3 "HEL-127, PATE-DJ" ENSG00000236027 "Prostate and testis expressed 3" B3GLJ2 11 125788127-125791600 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "epididymis: 154.4" "Cell type enhanced" "Detected in single" "Basal prostatic cells: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 3: Basal prostatic cells - Lipid metabolism" PATE4 "FLJ41047, PATE-B" ENSG00000237353 "Prostate and testis expressed 4" P0C8F1 11 125833316-125840072 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "seminal vesicle: 103.1" "Cell type enriched" "Detected in some" 18 "Basal prostatic cells: 458.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA045632 Approved "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 3: Basal prostatic cells - Lipid metabolism" "HPA045632: AB_10960489" "unprognostic (4.90e-1)" "unprognostic (2.93e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" PAX2 PAX-2 ENSG00000075891 "Paired box 2" Q02962 10 100735396-100829944 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 29.0;kidney: 83.0" "Group enriched" "Detected in some" 4 "Collecting duct cells: 134.2;Glandular and luminal cells: 231.1" "Group enriched" "Detected in some" 19 "endometrial cancer: 6.7;ovarian cancer: 7.0;renal cancer: 14.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Kidney cancer: 17.9;ovarian cancer: 5.4;Rhabdoid: 10.8;Uterine cancer: 8.5" "Group enriched" "Detected in some" 9 "cerebellum: 1.3;pons and medulla: 3.4" "Group enriched" "Detected in some" 6 "cerebellum: 5.2;medulla oblongata: 7.7;spinal cord: 6.9" "CAB013024, HPA047704, HPA070751" Enhanced Supported Nucleoplasm "Intracellular and membrane" "Developmental protein" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 2 Nucleoplasm "CAB013024: AB_2533990, HPA047704: AB_2636861, HPA070751: AB_2686305" "unprognostic (3.98e-2)" "unprognostic (9.55e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (4.85e-2)" "unprognostic (5.54e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-1)" "unprognostic (1.24e-2)" "unprognostic (6.59e-2)" "unprognostic (9.18e-2)" "unprognostic (3.30e-3)" "unprognostic (3.67e-1)" "unprognostic (1.97e-1)" "unprognostic (6.34e-2)" "unprognostic (8.26e-2)" PCCB ENSG00000114054 "Propionyl-CoA carboxylase subunit beta" P05166 3 136250340-136337896 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 195.7" "Cell type enhanced" "Detected in all" "Early spermatids: 244.8;Late spermatids: 233.6;Oocytes: 280.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036939, HPA036940" Enhanced "Intracellular and membrane" Enzyme NA NA 120000 "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 21: Early spermatids - Spermatogenesis" 2 "HPA036939: AB_10671366, HPA036940: AB_10669779" "unprognostic (2.74e-1)" "unprognostic (7.88e-3)" "unprognostic (3.99e-2)" "unprognostic (2.89e-2)" "unprognostic (2.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.05e-2)" "unprognostic (1.50e-1)" "unprognostic (2.31e-2)" "unprognostic (2.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.47e-7)" "unprognostic (2.43e-2)" "unprognostic (2.64e-1)" "unprognostic (3.50e-1)" "unprognostic (4.13e-1)" PCDH12 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 29.2" "Group enriched" "Detected in some" 4 "Adipocytes: 34.4;Endothelial cells: 25.7;Hofbauer cells: 32.4;Lymphatic endothelial cells: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.7" "Lineage enriched" "Detected in single" 41 "monocytes: 4.7" "Cancer enhanced" "Detected in some" "Myeloma: 3.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" "Cell adhesion" NA NA 14000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" PCDH15 "CDHR15, DFNB23, USH1F" ENSG00000150275 "Protocadherin related 15" Q96QU1 10 53802771-55627942 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 18.4;retina: 59.9" "Cell type enriched" "Detected in some" 13 "Oligodendrocyte precursor cells: 2782.3" "Cancer enriched" "Detected in single" 9 "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 6.3" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA074437 Supported "Intracellular and membrane" "Cell adhesion" NA NA 22000 "Cluster 76: Retina - Visual perception" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA074437: " "unprognostic (1.38e-1)" "unprognostic (3.39e-1)" "unprognostic (8.15e-5)" "unprognostic (3.07e-3)" "unprognostic (2.79e-1)" "unprognostic (9.15e-4)" "unprognostic (2.02e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-3)" "unprognostic (1.31e-3)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (7.66e-3)" PCDHA1 ENSG00000204970 "Protocadherin alpha 1" Q9Y5I3 5 140786136-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.8;pituitary gland: 1.0;testis: 1.0" "Cell type enhanced" "Detected in single" "Spermatocytes: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 4.0" "Testis - Early spermatids" "Low region specificity" "Detected in many" HPA035969 Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" "Secreted - unknown location" "Cell adhesion" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" "Endoplasmic reticulum, Golgi apparatus" "HPA035969: AB_10673492" "unprognostic (2.76e-5)" "unprognostic (1.19e-1)" "unprognostic (3.74e-2)" "unprognostic (1.09e-4)" "unprognostic (7.38e-2)" "unprognostic (2.86e-2)" "unprognostic (2.26e-3)" "unprognostic (1.25e-2)" "unprognostic (1.91e-2)" "unprognostic (1.81e-1)" "unprognostic (9.01e-5)" "unprognostic (2.46e-2)" "unprognostic (1.91e-1)" "unprognostic (7.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (1.29e-1)" PCDHA10 "CNR8, CNRN8, CNRS8, CRNR8, PCDH-ALPHA10" ENSG00000250120 "Protocadherin alpha 10" Q9Y5I2 5 140855883-141012347 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.9;Early spermatids: 9.2;Exocrine glandular cells: 4.6;Horizontal cells: 5.0;Mucus glandular cells: 5.7;Rod photoreceptor cells: 3.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 8.4" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Secreted - unknown location" "Cell adhesion" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "unprognostic (4.24e-2)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (4.70e-2)" "unprognostic (4.19e-1)" "unprognostic (2.36e-1)" "unprognostic (6.46e-2)" "unprognostic (8.24e-2)" "unprognostic (8.10e-2)" "unprognostic (5.28e-2)" "unprognostic (2.65e-1)" "unprognostic (6.14e-3)" "unprognostic (1.93e-2)" "unprognostic (3.57e-3)" "unprognostic (5.21e-2)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" PCDHA6 "CNR2, CNRS2, CRNR2, PCDH-ALPHA6" ENSG00000081842 "Protocadherin alpha 6" Q9UN73 5 140827958-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA059326, HPA078110" Enhanced Approved Vesicles "Secreted in brain" "Cell adhesion" NA NA "Cluster 28: Neuronal - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Vesicles "HPA059326: AB_2683980, HPA078110: AB_2732371" "unprognostic (1.15e-1)" "unprognostic (7.00e-2)" "unprognostic (5.07e-1)" "unprognostic (2.79e-1)" "unprognostic (4.39e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-4)" "unprognostic (4.23e-3)" "unprognostic (8.38e-2)" "unprognostic (2.55e-1)" "unprognostic (1.23e-3)" "unprognostic (3.44e-1)" "unprognostic (1.03e-2)" "unprognostic (2.66e-3)" "unprognostic (2.56e-1)" "unprognostic (5.66e-3)" "unprognostic (3.55e-2)" PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 4 "Bipolar cells: 3.0;Skeletal myocytes: 8.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 2: Skeletal myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.13e-2)" "unprognostic (1.78e-3)" "unprognostic (9.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.97e-1)" "unprognostic (2.22e-1)" "unprognostic (3.03e-2)" "unprognostic (3.74e-2)" "unprognostic (3.54e-1)" "unprognostic (4.34e-3)" "unprognostic (1.89e-1)" PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 500.3;Fibroblasts: 373.1;Leydig cells: 143.1;Smooth muscle cells: 206.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 209.7;Neuroblastoma: 253.8;Sarcoma: 172.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 106.9" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA 1300000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 3 "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" PCOLCE2 PCPE2 ENSG00000163710 "Procollagen C-endopeptidase enhancer 2" Q9UKZ9 3 142815922-142889206 "Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 84.7;heart muscle: 119.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 137.5;Extravillous trophoblasts: 68.1;Fibroblasts: 179.2;Syncytiotrophoblasts: 255.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Fibroblasts, Kidney - Podocytes, Prostate - Fibroblasts, Skin - Fibroblast_2, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA013203 Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" Other NA NA 580000 "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "HPA013203: AB_1855084" "unprognostic (1.31e-1)" "unprognostic (3.75e-2)" "unprognostic (5.71e-6)" "unprognostic (8.36e-6)" "unprognostic (3.03e-2)" "unprognostic (1.06e-3)" "unprognostic (2.78e-2)" "unprognostic (9.39e-2)" "unprognostic (1.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.74e-4)" "prognostic unfavorable (1.08e-4)" PCSK1 "NEC1, PC1, PC1/3, PC3, SPC3" ENSG00000175426 "Proprotein convertase subtilisin/kexin type 1" P29120 5 96390333-96434143 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.2;pituitary gland: 11.8" "Group enriched" "Detected in some" 8 "Enteroendocrine cells: 175.8;Excitatory neurons: 52.6;Pancreatic endocrine cells: 56.0" "Cancer enhanced" "Detected in many" "breast cancer: 12.1" "Region enhanced" "Detected in all" "hypothalamus: 173.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 27.1;thyroid cancer: 74.8" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048564, HPA079656" Approved "Secreted in other tissues" Enzyme NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA048564: AB_2680444, HPA079656: " "unprognostic (1.86e-2)" "unprognostic (2.13e-2)" "unprognostic (4.66e-3)" "unprognostic (8.20e-5)" "prognostic unfavorable (9.13e-5)" "unprognostic (8.47e-4)" "unprognostic (1.46e-1)" "unprognostic (5.84e-3)" "unprognostic (4.71e-1)" "unprognostic (3.07e-3)" "unprognostic (1.89e-3)" "unprognostic (1.01e-1)" "unprognostic (7.90e-6)" "unprognostic (5.25e-2)" "unprognostic (9.96e-2)" "unprognostic (1.33e-3)" "unprognostic (9.37e-3)" PCSK1N "BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII" ENSG00000102109 "Proprotein convertase subtilisin/kexin type 1 inhibitor" Q9UHG2 X 48831096-48835610 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 776.1;pituitary gland: 1211.0" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 4436.2;Proximal tubular cells: 1348.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 2.4;memory CD4 T-cell: 5.0;memory CD8 T-cell: 4.9;naive CD4 T-cell: 2.0;naive CD8 T-cell: 6.4;T-reg: 1.8" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003925, HPA064734" Enhanced Supported Approved Vesicles "Secreted to blood" Neuropeptide NA NA 3300000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" Vesicles "HPA003925: AB_1079582, HPA064734: AB_2685339" "unprognostic (2.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (3.36e-1)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.79e-3)" "prognostic favorable (1.36e-4)" "unprognostic (3.34e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 27.6;retina: 34.7;thyroid gland: 55.2" "Cell type enhanced" "Detected in many" "Early spermatids: 102.5;Excitatory neurons: 312.0;Inhibitory neurons: 142.1;Melanocytes: 348.7;Muller glia cells: 398.8;Schwann cells: 120.0" "Cancer enriched" "Detected in many" 4 "thyroid cancer: 65.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 30.0;lung cancer: 15.9;thyroid cancer: 12.7" "Adipose subcutaneous - Smooth muscle cells, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Skin - Melanocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" Enzyme NA NA 18000 "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA049627: AB_2680835" "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362975 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 25.2" "Cell type enhanced" "Detected in many" "Astrocytes: 179.9;Inhibitory neurons: 78.0;Oligodendrocyte precursor cells: 140.1;Proximal enterocytes: 149.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 4.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA 290000 "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 10 "Golgi apparatus" "HPA031072: AB_10602190" "unprognostic (3.28e-2)" "unprognostic (1.44e-1)" "unprognostic (4.13e-4)" "unprognostic (4.08e-2)" "unprognostic (7.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-3)" "unprognostic (9.39e-2)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (2.81e-2)" "unprognostic (6.80e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (2.99e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-5)" PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.3;liver: 154.8;lymphoid tissue: 79.2" "Group enriched" "Detected in many" 6 "Hepatocytes: 186.9;Oligodendrocytes: 523.0" "Cancer enhanced" "Detected in many" "liver cancer: 8.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Hepatocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" Enzyme NA NA 480000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" 1 "HPA004774: AB_1079583" "prognostic favorable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" PCSK9 "FH3, HCHOLA3, NARC-1" ENSG00000169174 "Proprotein convertase subtilisin/kexin type 9" Q8NBP7 1 55039447-55064852 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 47.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 31.1;Hepatocytes: 28.2;Kupffer cells: 13.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 6 "cerebellum: 7.1;medulla oblongata: 1.8;pons: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" Enzyme NA NA 143000000 420000000 "Cluster 83: Liver - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Hepatocytes - Metabolism" 3 "unprognostic (1.28e-3)" "unprognostic (6.93e-2)" "unprognostic (4.02e-1)" "unprognostic (2.19e-2)" "unprognostic (7.30e-2)" "unprognostic (1.82e-1)" "unprognostic (1.20e-3)" "unprognostic (1.14e-2)" "unprognostic (5.44e-3)" "unprognostic (1.22e-2)" "unprognostic (2.09e-3)" "unprognostic (3.70e-2)" "unprognostic (2.45e-4)" "unprognostic (1.49e-1)" "unprognostic (1.86e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (2.40e-4)" PCYOX1 "KIAA0908, PCL1" ENSG00000116005 "Prenylcysteine oxidase 1" Q9UHG3 2 70257386-70281185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035193 Approved "Intracellular and membrane" Enzyme NA NA 510000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA035193: AB_10602017" "unprognostic (1.09e-1)" "unprognostic (1.72e-2)" "unprognostic (7.91e-2)" "unprognostic (1.15e-2)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (6.87e-2)" "unprognostic (6.28e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (1.61e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.26e-2)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" PCYOX1L MGC3265 ENSG00000145882 "Prenylcysteine oxidase 1 like" Q8NBM8 5 149358037-149369653 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oocytes: 16.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037463, HPA038402" Approved Approved Nucleoplasm,Mitochondria "Secreted to blood" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 57: Platelets - Hemostasis" "Nucleoplasm, Mitochondria" "HPA037463: AB_10673632, HPA038402: AB_2675997" "unprognostic (1.34e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (1.22e-1)" "unprognostic (7.83e-2)" "unprognostic (5.73e-2)" "unprognostic (4.18e-3)" "unprognostic (7.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.25e-1)" "unprognostic (3.05e-3)" "unprognostic (8.77e-2)" "unprognostic (4.90e-2)" "unprognostic (2.86e-1)" "unprognostic (2.49e-1)" "unprognostic (2.26e-3)" "unprognostic (3.28e-1)" PDCD1LG2 "B7-DC, bA574F11.2, Btdc, CD273, PD-L2, PDL2" ENSG00000197646 "Programmed cell death 1 ligand 2" Q9BQ51 9 5510531-5571282 "Cancer-related genes, CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 21.7;Fibroblasts: 7.3;granulocytes: 11.8;Langerhans cells: 13.9;Leydig cells: 6.8;Microglial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013411 Approved Uncertain Cytosol "Secreted - unknown location" Receptor NA NA 31000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 14: Langerhans cells - Innate immune response" 18 Cytosol "HPA013411: AB_1855102" "unprognostic (3.93e-2)" "unprognostic (1.90e-1)" "unprognostic (3.51e-3)" "unprognostic (6.68e-3)" "unprognostic (7.66e-2)" "unprognostic (6.77e-2)" "unprognostic (5.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.68e-1)" "unprognostic (4.37e-3)" "unprognostic (5.79e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (5.00e-2)" "unprognostic (4.66e-2)" "unprognostic (2.01e-1)" "unprognostic (7.51e-3)" PDCD6IP "AIP1, Alix, Hp95" ENSG00000170248 "Programmed cell death 6 interacting protein" Q8WUM4 3 33798571-33869707 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Host-virus interaction, Protein transport, Transport" "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011905, CAB016212, HPA051110, HPA051604" Supported Approved Vesicles,Centrosome "Intracellular and membrane" Transport NA NA 4100000 "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" 15 Vesicles Centrosome "CAB016212: AB_673819, HPA011905: AB_1855111, HPA051110: , HPA051604: " "unprognostic (1.53e-1)" "unprognostic (2.63e-1)" "prognostic favorable (1.16e-4)" "unprognostic (2.17e-1)" "unprognostic (2.75e-1)" "unprognostic (5.12e-2)" "unprognostic (7.76e-3)" "unprognostic (1.23e-2)" "unprognostic (3.29e-1)" "unprognostic (2.86e-1)" "unprognostic (3.88e-3)" "unprognostic (4.49e-2)" "prognostic favorable (3.90e-9)" "unprognostic (9.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.78e-1)" "unprognostic (1.11e-1)" PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623244-178108339 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 6.1;parathyroid gland: 9.9" "Cell type enriched" "Detected in many" 7 "Prostatic glandular cells: 139.2" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Kidney cancer: 6.5;Rhabdoid: 7.5" "Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034560 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 40: Prostatic glandular cells - Transcription" "HPA034560: AB_10602140" "unprognostic (1.02e-1)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.61e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.91e-1)" "unprognostic (9.95e-2)" "unprognostic (2.80e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-4)" "unprognostic (1.64e-3)" PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69326913-69330588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 27.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 9.5;Erythroid cells: 4.1;Gastric mucus-secreting cells: 8.3;Mesothelial cells: 7.7;Plasma cells: 12.3;Squamous epithelial cells: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Enzyme No No "Cluster 45: Eosinophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 61: Plasma cells - Immunoglobulins & histones" Mitochondria Nucleoplasm "HPA063409: AB_2685007" "unprognostic (4.28e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (1.37e-1)" "unprognostic (1.47e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.35e-4)" "unprognostic (5.84e-2)" "unprognostic (4.35e-1)" "unprognostic (1.02e-1)" "unprognostic (1.00e-1)" "prognostic favorable (6.11e-4)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-2)" PDGFA "PDGF-A, PDGF1" ENSG00000197461 "Platelet derived growth factor subunit A" P04085 7 497258-520296 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 77.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 104.0;Breast myoepithelial cells: 181.5;Smooth muscle cells: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 9.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005579, HPA065024" Approved Approved "Golgi apparatus" "Secreted to blood" "Growth factor" NA NA 580000 "Cluster 24: Non-specific - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 67: Non-specific - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" 2 "Golgi apparatus" "CAB005579: AB_2161916, HPA065024: " "unprognostic (2.22e-1)" "unprognostic (2.83e-1)" "unprognostic (1.17e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.75e-4)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.63e-3)" "unprognostic (4.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.85e-1)" "unprognostic (8.26e-2)" "unprognostic (1.07e-2)" "unprognostic (5.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (8.67e-4)" PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 128.6;dendritic cells: 66.4;Endothelial cells: 69.3;Langerhans cells: 76.9;Macrophages: 52.8;Schwann cells: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Enteric glia cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" "Growth factor" NA NA 4390000 950000 "Cluster 1: T-cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Dendritic cells - Antigen presentation" 4 Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" PDGFC "fallotein, SCDGF" ENSG00000145431 "Platelet derived growth factor C" Q9NRA1 4 156760454-156971799 "Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 19.6" "Cell type enhanced" "Detected in many" "Astrocytes: 93.5;Granulosa cells: 81.6;Microglial cells: 81.4;Oligodendrocyte precursor cells: 218.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009134 Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" "Growth factor" NA NA 37000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "Plasma membrane, Cytosol" "HPA009134: AB_10601981" "unprognostic (3.12e-1)" "unprognostic (1.91e-2)" "unprognostic (5.79e-2)" "unprognostic (3.67e-2)" "unprognostic (3.97e-1)" "unprognostic (3.41e-2)" "unprognostic (8.78e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.35e-5)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.25e-1)" "unprognostic (1.19e-2)" "prognostic unfavorable (3.17e-4)" PDGFD "IEGF, MSTP036, SCDGF-B" ENSG00000170962 "Platelet derived growth factor D" Q9GZP0 11 103907189-104164379 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 103.4" "Cell type enhanced" "Detected in many" "Ductal cells: 36.5;Fibroblasts: 43.6;Inhibitory neurons: 91.0;Mesothelial cells: 50.8;NK-cells: 52.1;Ovarian stromal cells: 57.2" "Cancer enhanced" "Detected in all" "renal cancer: 17.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 9.5;gdT-cell: 16.4;memory CD8 T-cell: 7.2;naive CD8 T-cell: 6.0;NK-cell: 17.1" "Group enriched" "Detected in many" 29 "granulocytes: 9.5;NK-cells: 17.1;T-cells: 16.4" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 51.0" "HPA046183, HPA066271" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Growth factor" NA NA 95000 "Cluster 15: NK-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 65: Neurons - Synaptic function" "Golgi apparatus, Vesicles" "HPA046183: AB_2679573, HPA066271: AB_2685645" "unprognostic (2.21e-1)" "unprognostic (9.35e-2)" "unprognostic (5.60e-2)" "unprognostic (1.72e-1)" "unprognostic (5.81e-2)" "unprognostic (8.83e-2)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (2.26e-1)" "unprognostic (7.01e-3)" "prognostic unfavorable (9.60e-4)" "unprognostic (1.19e-1)" "unprognostic (6.72e-2)" "unprognostic (3.57e-3)" PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 193.9" "Group enriched" "Detected in many" 9 "Endometrial stromal cells: 368.4;Fibroblasts: 258.5;Leydig cells: 422.2;Oligodendrocyte precursor cells: 468.8;Ovarian stromal cells: 204.8;Peritubular cells: 377.5" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 78.7;thyroid cancer: 38.5" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" Receptor NA NA 300000 "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 5 "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 63.5" "Cell type enhanced" "Detected in many" "Early spermatids: 51.6;Fibroblasts: 171.1;Leydig cells: 69.2;Oocytes: 147.8;Ovarian stromal cells: 40.1;Peritubular cells: 67.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 26.7" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" "No annotated function" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" PDIA2 "PDA2, PDI, PDIP, PDIR" ENSG00000185615 "Protein disulfide isomerase family A member 2" Q13087 16 283164-287215 "Enzymes, Predicted intracellular proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "pancreas: 2430.7" "Group enriched" "Detected in some" 5 "Exocrine glandular cells: 162.0;Gastric mucus-secreting cells: 73.1" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 12.1;Myeloma: 26.1" "Colon - Enteric glia cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA051692, HPA053492" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 2 "HPA051692: AB_2681575, HPA053492: AB_2682169" "unprognostic (3.46e-2)" "unprognostic (7.98e-3)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" "unprognostic (2.17e-2)" "unprognostic (6.27e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-1)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (2.90e-2)" "unprognostic (1.58e-14)" "unprognostic (3.06e-2)" "unprognostic (1.66e-1)" "unprognostic (8.75e-2)" "unprognostic (2.87e-2)" PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746394-43773279 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 302.7" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1108.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 200000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 51: Thyroid gland - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 8 "Endoplasmic reticulum" "CAB011199: AB_609902, CAB015181: AB_2160857, CAB075744: AB_2665750, HPA002645: AB_1079031, HPA003230: AB_1079030" "unprognostic (9.20e-2)" "unprognostic (1.21e-3)" "unprognostic (1.34e-1)" "prognostic favorable (2.05e-4)" "unprognostic (2.40e-2)" "prognostic unfavorable (8.95e-5)" "unprognostic (1.67e-1)" "unprognostic (8.60e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.11e-8)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (6.63e-2)" PDIA4 "ERP70, ERP72" ENSG00000155660 "Protein disulfide isomerase family A member 4" P13667 7 149003062-149028662 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 413.7;Hepatocytes: 454.4;Plasma cells: 569.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006139, HPA006140, CAB017368" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 15000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 53: Non-specific - Glycosylation" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 7 "Endoplasmic reticulum" "CAB017368: AB_10621725, HPA006139: AB_1848256, HPA006140: AB_1848257" "unprognostic (1.98e-1)" "unprognostic (1.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.97e-2)" "unprognostic (1.81e-1)" "unprognostic (2.11e-2)" "unprognostic (5.11e-2)" "unprognostic (3.24e-3)" "unprognostic (6.08e-3)" "unprognostic (3.20e-2)" "prognostic unfavorable (5.20e-9)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" PDIA5 "FLJ30401, PDIR" ENSG00000065485 "Protein disulfide isomerase family A member 5" Q14554 3 123067025-123225227 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 77.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 153.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 12.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030353, HPA030355" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 4700000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 4: Extravillous trophoblasts - Unknown function" 2 "Nucleoplasm, Golgi apparatus" "Nucleoli fibrillar center" "HPA030353: AB_10599734, HPA030355: AB_10602200" "unprognostic (8.81e-2)" "unprognostic (2.25e-2)" "unprognostic (8.93e-2)" "prognostic favorable (4.55e-4)" "unprognostic (4.34e-2)" "unprognostic (2.10e-2)" "unprognostic (7.38e-2)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (4.02e-2)" "unprognostic (1.55e-1)" "unprognostic (2.26e-3)" "prognostic unfavorable (8.09e-11)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (1.06e-2)" "unprognostic (4.06e-3)" PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1335.8;Plasma cells: 981.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Enzyme NA NA 15000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 5 "Endoplasmic reticulum, Cytosol" "CAB034347: AB_2299360, HPA034652: AB_2674263, HPA034653: AB_10601982" "unprognostic (8.16e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.20e-4)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" "unprognostic (5.25e-3)" "unprognostic (6.03e-3)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (6.59e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-2)" "unprognostic (3.69e-3)" PDILT PDIA7 ENSG00000169340 "Protein disulfide isomerase like, testis expressed" Q8N807 16 20359175-20404737 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Chaperone, Developmental protein, Isomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "stomach 1: 119.4" "Cell type enriched" "Detected in some" 5 "Early spermatids: 165.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041913 Approved "Intracellular and membrane" "Developmental protein" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" "HPA041913: AB_10795644" "unprognostic (1.99e-1)" "unprognostic (6.09e-2)" "unprognostic (2.05e-3)" "unprognostic (2.63e-1)" PDYN "ADCA, PENKB, SCA23" ENSG00000101327 Prodynorphin P01213 20 1978757-1994285 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Neurotransmitter, Opioid peptide" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 112.4" "Group enriched" "Detected in some" 47 "Early spermatids: 42.5;Late spermatids: 120.6" "Group enriched" "Detected in some" 29 "glioma: 2.6;ovarian cancer: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Bone cancer: 3.9" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 4 "basal ganglia: 152.2;hypothalamus: 60.7" "Region enhanced" "Detected in many" "basal ganglia: 173.9" "HPA053342, CAB079777" Enhanced Supported "Secreted in brain" Neuropeptide NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 36: Late spermatids - Unknown function" "CAB079777: , HPA053342: AB_2682121" "unprognostic (7.00e-2)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" "unprognostic (3.73e-2)" PDZD11 PDZK11 ENSG00000120509 "PDZ domain containing 11" Q5EBL8 X 70281118-70290514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003972 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 33: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" 3 "HPA003972: AB_1855165" "unprognostic (1.51e-2)" "unprognostic (1.70e-3)" "unprognostic (2.75e-1)" "unprognostic (3.52e-1)" "unprognostic (9.89e-2)" "unprognostic (1.12e-3)" "unprognostic (1.89e-3)" "unprognostic (2.38e-1)" "unprognostic (1.20e-1)" "unprognostic (2.87e-3)" "unprognostic (5.44e-2)" "unprognostic (2.89e-2)" "unprognostic (1.43e-2)" "unprognostic (2.15e-1)" "unprognostic (1.33e-3)" "unprognostic (1.28e-2)" "unprognostic (3.72e-3)" PDZD2 "KIAA0300, PDZK3" ENSG00000133401 "PDZ domain containing 2" O15018 5 31639131-32110932 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 18.1" "Cell type enhanced" "Detected in many" "Early spermatids: 264.1;Excitatory neurons: 303.6;Oligodendrocyte precursor cells: 699.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "CAB020784, HPA036503, HPA036504, HPA064387, HPA076072" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 53: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "CAB020784: , HPA036503: AB_2675161, HPA036504: , HPA064387: AB_2685252, HPA076072: " "unprognostic (3.65e-2)" "unprognostic (4.06e-2)" "unprognostic (6.63e-2)" "unprognostic (5.42e-5)" "unprognostic (2.39e-1)" "unprognostic (9.67e-3)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (3.38e-2)" "unprognostic (2.45e-2)" "unprognostic (1.71e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-3)" "unprognostic (4.13e-2)" "unprognostic (6.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.79e-1)" PDZD8 "bA129M16.2, FLJ34427, PDZK8" ENSG00000165650 "PDZ domain containing 8" Q8NEN9 10 117277274-117375440 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Lipid transport, Transport" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 72.2" "Cell type enhanced" "Detected in all" "Early spermatids: 177.6;Late spermatids: 470.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015716, HPA051610" Uncertain Approved "Nucleoli fibrillar center,Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 6: Bone marrow - Innate immune response" "Cluster 45: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 36: Late spermatids - Unknown function" "Nucleoli fibrillar center" "Plasma membrane" "HPA015716: AB_1855162, HPA051610: AB_2681549" "unprognostic (1.12e-1)" "unprognostic (2.87e-1)" "unprognostic (9.65e-3)" "unprognostic (2.75e-2)" "unprognostic (6.29e-2)" "unprognostic (3.36e-2)" "unprognostic (2.42e-1)" "unprognostic (1.43e-1)" "unprognostic (2.53e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.90e-2)" "unprognostic (5.37e-3)" "unprognostic (7.60e-3)" "unprognostic (1.44e-2)" "unprognostic (3.18e-2)" "unprognostic (2.01e-2)" PEBP4 "CORK1, hPEBP4, MGC22776" ENSG00000134020 "Phosphatidylethanolamine binding protein 4" Q96S96 8 22713251-23000000 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 373.3;skeletal muscle: 647.4;tongue: 557.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 208.2;Alveolar cells type 2: 452.9;Cardiomyocytes: 131.9;Muller glia cells: 177.2;Skeletal myocytes: 342.5" "Group enriched" "Detected in many" 13 "lung cancer: 11.4;prostate cancer: 23.7;thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "prostate cancer: 9.4" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pancreas - Exocrine glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025064 Uncertain "Secreted in other tissues" "No annotated function" NA NA 190000000 "Cluster 20: Non-specific - DNA binding" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 72: Alveolar cells - Lung function" 2 "HPA025064: AB_1855174" "unprognostic (1.34e-2)" "unprognostic (2.97e-2)" "unprognostic (4.11e-2)" "unprognostic (3.66e-1)" "unprognostic (3.35e-1)" "unprognostic (4.78e-2)" "unprognostic (1.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "unprognostic (8.76e-3)" "unprognostic (9.70e-8)" "unprognostic (1.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.48e-1)" "unprognostic (4.59e-1)" PENK ENSG00000181195 Proenkephalin P01210 8 56436674-56446671 "Plasma proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 365.1;brain: 738.6" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 703.2;Leydig cells: 1159.4" "Cancer enhanced" "Detected in many" "lung cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 795.3" "Heart muscle - Fibroblasts, Skin - Fibroblast_2, Testis - Early spermatids" "Region enriched" "Detected in all" 7 "basal ganglia: 3628.7" "Region enriched" "Detected in all" 7 "basal ganglia: 1199.3" "HPA013138, CAB016390" Enhanced Approved Vesicles "Secreted in other tissues" Neuropeptide NA NA 220000 "Cluster 40: Monocytes - Innate immune response" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" Vesicles "CAB016390: AB_2161515, HPA013138: AB_1855191" "unprognostic (6.89e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (1.17e-3)" "unprognostic (1.56e-2)" "unprognostic (3.58e-3)" "unprognostic (1.31e-2)" "unprognostic (3.60e-1)" "unprognostic (6.34e-2)" "unprognostic (5.73e-2)" "unprognostic (3.47e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.98e-3)" PET117 CSRP2BP ENSG00000232838 "PET117 cytochrome c oxidase chaperone" Q6UWS5 20 18137863-18143169 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047716 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Non-specific - Basic cellular processes" "HPA047716: AB_2680128" "unprognostic (1.34e-2)" "unprognostic (2.83e-1)" "unprognostic (3.94e-1)" "unprognostic (2.02e-1)" "unprognostic (2.39e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (4.76e-6)" "unprognostic (7.74e-2)" "unprognostic (1.25e-1)" "unprognostic (3.13e-2)" "unprognostic (4.90e-1)" "unprognostic (2.78e-1)" "prognostic favorable (4.15e-4)" "unprognostic (3.73e-1)" "unprognostic (4.63e-1)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" PF4 "CXCL4, SCYB4" ENSG00000163737 "Platelet factor 4" P02776 4 73980811-73982027 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "bone marrow: 29.2;lung: 10.2;lymphoid tissue: 30.8" "Cell type enhanced" "Detected in some" "B-cells: 6.3;Ductal cells: 5.9;Enteroendocrine cells: 9.3;Granulosa cells: 30.8;NK-cells: 24.9" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.9" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.0" "Not detected" "Not detected" "CAB026008, HPA052485" Enhanced "Secreted to blood" Cytokine NA NA 7700000 "Cluster 4: Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 20 "CAB026008: , HPA052485: AB_2681847" "unprognostic (4.14e-4)" "unprognostic (1.00e-2)" "unprognostic (2.49e-1)" "unprognostic (1.96e-4)" "unprognostic (7.58e-2)" "unprognostic (1.42e-1)" "unprognostic (7.55e-2)" "unprognostic (2.04e-1)" "unprognostic (9.02e-3)" "unprognostic (1.84e-2)" "unprognostic (3.03e-2)" "unprognostic (9.54e-5)" "unprognostic (2.55e-1)" "unprognostic (8.77e-2)" "unprognostic (9.69e-2)" "unprognostic (4.81e-2)" PF4V1 "CXCL4L1, CXCL4V1, SCYB4V1" ENSG00000109272 "Platelet factor 4 variant 1" P10720 4 73853296-73854483 "Plasma proteins, Predicted secreted proteins" "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.6;lymphoid tissue: 2.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 17.2;Club cells: 10.7;Enteroendocrine cells: 16.0;Hepatocytes: 4.0" "Cancer enhanced" "Detected in some" "renal cancer: 3.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 42 "basophil: 12.5;neutrophil: 9.2" "Lineage enriched" "Detected in single" 48 "granulocytes: 12.5" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.2" HPA052485 Supported "Secreted to blood" Cytokine NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 57: Platelets - Hemostasis" 1 "HPA052485: AB_2681847" "unprognostic (4.95e-1)" "unprognostic (5.68e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-3)" "unprognostic (9.88e-2)" "unprognostic (1.72e-2)" "unprognostic (1.68e-3)" "unprognostic (2.66e-1)" "unprognostic (6.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.95e-3)" "unprognostic (1.39e-2)" "unprognostic (2.11e-1)" PGA3 ENSG00000229859 "Pepsinogen A3" P0DJD8 11 61203307-61213098 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 613 "stomach 1: 86662.3" "Cell type enriched" "Detected in some" 29 "Gastric mucus-secreting cells: 3595.7" "Cancer enriched" "Detected in single" 498 "stomach cancer: 24.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "CAB026358, HPA046875" Enhanced "Secreted to digestive system" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 29: Forebrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 46: Gastric mucus-secreting cells - Digestion" "CAB026358: , HPA046875: AB_2679851" "unprognostic (6.39e-2)" "unprognostic (1.11e-1)" PGA4 ENSG00000229183 "Pepsinogen A4" P0DJD7 11 61222347-61231694 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1277 "stomach 1: 64644.4" "Group enriched" "Detected in some" 12 "Exocrine glandular cells: 38.9;Gastric mucus-secreting cells: 17.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "classical monocyte: 9.9;intermediate monocyte: 10.8;non-classical monocyte: 3.4" "Lineage enriched" "Detected in single" 26 "monocytes: 10.8" "Not detected" "Not detected" "Stomach - Chief cells" HPA046875 Supported "Secreted to digestive system" Enzyme NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Stomach - Proteolysis" "Cluster 49: HMC-1 - Innate immune response" "Cluster 45: Non-specific - Mixed function" 8 "HPA046875: AB_2679851" "unprognostic (2.22e-1)" PGA5 ENSG00000256713 "Pepsinogen A5" P0DJD9 11 61241175-61251444 "Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Aspartyl protease, Hydrolase, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2028 "stomach 1: 38780.0" "Cell type enriched" "Detected in some" 22 "Exocrine glandular cells: 1696.1" "Cancer enriched" "Detected in some" 12 "stomach cancer: 15.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 29 "classical monocyte: 1.8;intermediate monocyte: 4.3;non-classical monocyte: 2.4" "Lineage enriched" "Detected in single" 44 "monocytes: 4.3" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Stomach - Chief cells" HPA046875 Supported "Secreted to digestive system" Enzyme NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" "HPA046875: AB_2679851" "unprognostic (1.36e-3)" "unprognostic (2.98e-2)" "unprognostic (5.83e-3)" "unprognostic (2.11e-1)" "unprognostic (4.22e-1)" "unprognostic (4.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (7.10e-2)" PGAM5 "BXLBv68, MGC5352" ENSG00000247077 "PGAM family member 5, mitochondrial serine/threonine protein phosphatase" Q96HS1 12 132710819-132722734 "Enzymes, Predicted intracellular proteins" Necrosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036978, HPA036979, CAB068215" Enhanced Supported Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB068215: AB_2665674, HPA036978: AB_10964347, HPA036979: AB_10960559" "unprognostic (9.57e-2)" "unprognostic (2.00e-2)" "unprognostic (3.83e-2)" "unprognostic (3.11e-2)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.13e-6)" "unprognostic (3.32e-2)" "unprognostic (1.47e-1)" "unprognostic (5.67e-2)" "unprognostic (1.23e-1)" "unprognostic (6.92e-2)" "unprognostic (6.42e-3)" "unprognostic (1.63e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (5.53e-2)" PGC ENSG00000096088 Progastricsin P20142 6 41736711-41754109 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Digestion "Aspartyl protease, Hydrolase, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "stomach 1: 58186.3" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 2414.1;Gastric mucus-secreting cells: 6176.1" "Cancer enhanced" "Detected in many" "stomach cancer: 1050.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "Gastric cancer: 347.9" "Lung - Alveolar cells type 2, Stomach - Chief cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031717, HPA031718" Enhanced Approved Nucleoplasm "Secreted to digestive system" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 2: Neurons - Nucleosome" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 3: Basal prostatic cells - Lipid metabolism" Nucleoplasm "HPA031717: AB_10670130, HPA031718: AB_10610148" "unprognostic (9.18e-2)" "unprognostic (1.87e-1)" "unprognostic (9.83e-2)" "unprognostic (2.27e-1)" "unprognostic (7.18e-2)" "unprognostic (2.74e-1)" "unprognostic (1.47e-1)" "unprognostic (8.50e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.33e-2)" "unprognostic (2.92e-1)" "unprognostic (1.65e-1)" "unprognostic (8.74e-2)" PGF "D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760" ENSG00000119630 "Placental growth factor" P49763 14 74941834-74955626 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 50.6;thyroid gland: 51.0" "Group enriched" "Detected in many" 21 "Extravillous trophoblasts: 1887.4;Syncytiotrophoblasts: 2188.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 41.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.2" HPA041624 Approved Nucleoplasm,Mitochondria,Cytosol "Secreted to blood" "Growth factor" No No 20800 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 Nucleoplasm "Mitochondria, Cytosol" "HPA041624: AB_10794522" "unprognostic (1.67e-2)" "unprognostic (4.62e-2)" "unprognostic (9.25e-3)" "unprognostic (1.34e-3)" "unprognostic (8.67e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (7.26e-2)" "unprognostic (1.48e-1)" "unprognostic (4.45e-1)" "unprognostic (1.45e-2)" "unprognostic (3.51e-3)" "prognostic unfavorable (1.33e-6)" "unprognostic (2.52e-3)" "unprognostic (1.20e-1)" "unprognostic (3.49e-2)" "unprognostic (1.14e-1)" PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023053 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 622.9" "Cell type enriched" "Detected in some" 4 "Oocytes: 7.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 202 "eosinophil: 445.1;neutrophil: 497.3" "Lineage enriched" "Detected in many" 213 "granulocytes: 497.3" "Low cancer specificity" "Detected in some" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045702, HPA070227" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" Immunity NA NA 35000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" Vesicles "Nucleoplasm, Cytosol" "HPA045702: AB_10960204, HPA070227: " "unprognostic (2.87e-2)" "unprognostic (4.26e-1)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.58e-1)" "unprognostic (4.93e-3)" "unprognostic (2.20e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (8.51e-3)" "unprognostic (7.18e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-3)" PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "liver: 250.7" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 132.3" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;monocytes: 5.1;T-cells: 2.3" "Group enriched" "Detected in some" 4 "Bone cancer: 4.9;breast cancer: 5.8" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" Immunity NA NA 87000000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 31: Liver - Plasma proteins" "Cluster 27: Breast cancer - Unknown function" "Cluster 43: Hepatocytes - Metabolism" "Cell Junctions" "CAB033468: AB_1127187, HPA046311: AB_2679621, HPA075237: AB_2686739" "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" PGLYRP3 "PGLYRPIalpha, PGRP-Ialpha, PGRPIA" ENSG00000159527 "Peptidoglycan recognition protein 3" Q96LB9 1 153297116-153312952 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 30.4;skin 1: 50.7;vagina: 20.7" "Group enriched" "Detected in some" 4 "granulocytes: 1.6;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 2.4" "Cancer enhanced" "Detected in many" "cervical cancer: 8.9;head and neck cancer: 16.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "basophil: 8.4;eosinophil: 3.7" "Lineage enriched" "Detected in single" 55 "granulocytes: 8.4" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.9" "Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA030369 Uncertain "Secreted in other tissues" Immunity NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 11 "HPA030369: AB_10603984" "unprognostic (6.34e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-2)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (3.88e-3)" "unprognostic (1.28e-1)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348841 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 8.3;esophagus: 7.9;skin 1: 14.6;vagina: 9.9" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 30.5;Ionocytes: 13.3;Suprabasal keratinocytes: 21.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "head and neck cancer: 7.3" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB025879 Approved "Vesicles,Plasma membrane" "Secreted in other tissues" Immunity NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (2.76e-2)" "unprognostic (1.19e-1)" "unprognostic (6.10e-2)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" PHB1 PHB ENSG00000167085 "Prohibitin 1" P35232 17 49404049-49414905 "Plasma proteins, Predicted intracellular proteins, Transporters" "DNA synthesis, Host-virus interaction" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA003280 Supported Supported Mitochondria "Intracellular and membrane" Other NA NA 360000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Mixed function" 6 Mitochondria "HPA003280: AB_1855732" "unprognostic (2.31e-2)" "unprognostic (5.70e-2)" "unprognostic (1.19e-2)" "unprognostic (7.88e-3)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.58e-4)" "prognostic unfavorable (9.91e-4)" "unprognostic (5.81e-2)" "unprognostic (4.40e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (7.36e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.10e-2)" "unprognostic (1.77e-1)" "unprognostic (2.71e-2)" "unprognostic (3.09e-3)" PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715541-62980433 "Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 32.0" "Group enriched" "Detected in many" 10 "Astrocytes: 401.9;Oligodendrocyte precursor cells: 505.1;Oligodendrocytes: 1548.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 4.0;T-reg: 1.3" "Group enriched" "Detected in many" 7 "granulocytes: 4.0;T-cells: 1.3" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 33: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 51: Oligodendrocytes - Unknown function" 12 "HPA020200: AB_2670383" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.07e-2)" "unprognostic (5.57e-2)" "unprognostic (5.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.10e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "prognostic favorable (5.35e-8)" "unprognostic (1.52e-1)" "unprognostic (3.49e-2)" "unprognostic (8.13e-2)" "unprognostic (8.25e-2)" PI15 P25TI ENSG00000137558 "Peptidase inhibitor 15" O43692 8 74824534-74855029 "Predicted secreted proteins" "Developmental protein, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.9;prostate: 30.0;smooth muscle: 48.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 54.0;Breast myoepithelial cells: 11.6;Endometrial stromal cells: 8.4;Prostatic glandular cells: 32.6;Smooth muscle cells: 16.5" "Group enriched" "Detected in many" 7 "breast cancer: 11.1;melanoma: 8.6;prostate cancer: 18.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Rhabdoid: 99.9;Sarcoma: 118.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 8.3" "HPA006593, HPA030057" Uncertain Approved Vesicles,Cytosol "Secreted in other tissues" "Developmental protein" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 17: Breast glandular cells - Lactation" Vesicles Cytosol "HPA006593: AB_1078568, HPA030057: AB_10602143" "unprognostic (2.77e-1)" "unprognostic (1.57e-2)" "unprognostic (3.41e-1)" "unprognostic (1.88e-2)" "unprognostic (3.22e-1)" "unprognostic (3.24e-1)" "unprognostic (2.94e-2)" "unprognostic (2.33e-3)" "unprognostic (1.87e-1)" "unprognostic (2.25e-1)" "unprognostic (3.65e-2)" "unprognostic (1.85e-2)" "unprognostic (8.63e-14)" "unprognostic (2.54e-3)" "unprognostic (1.34e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" PI16 "CD364, dJ90K10.5, MGC45378, MSMBBP" ENSG00000164530 "Peptidase inhibitor 16" Q6UXB8 6 36948263-36964837 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 135.5;heart muscle: 123.5;vagina: 123.4" "Group enriched" "Detected in many" 6 "Fibroblasts: 179.7;Leydig cells: 199.8;Oligodendrocytes: 62.7;Peritubular cells: 141.8" "Cancer enhanced" "Detected in many" "glioma: 15.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 66.3" "Lineage enriched" "Detected in many" 5 "T-cells: 66.3" "Cancer enriched" "Detected in some" 12 "Kidney cancer: 17.7" "Adipose subcutaneous - Adipose progenitor cells, Colon - Fibroblasts, Heart muscle - Fibroblasts, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 45.1" HPA076574 Approved "Secreted to blood" "Enzyme inhibitor" NA NA 2900000000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 5 "HPA076574: AB_2732314" "unprognostic (6.24e-3)" "unprognostic (6.00e-3)" "unprognostic (7.34e-2)" "unprognostic (9.53e-2)" "unprognostic (3.38e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-2)" "unprognostic (5.06e-2)" "unprognostic (6.48e-2)" "unprognostic (1.88e-1)" "unprognostic (3.25e-2)" "unprognostic (4.46e-2)" "unprognostic (1.59e-3)" "unprognostic (5.82e-2)" "unprognostic (2.31e-1)" "unprognostic (1.28e-1)" "unprognostic (8.76e-2)" PI3 "cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14" ENSG00000124102 "Peptidase inhibitor 3" P19957 20 45174902-45176544 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2191.5;lymphoid tissue: 2040.9;vagina: 1548.4" "Group enriched" "Detected in many" 6 "Basal respiratory cells: 6262.1;Ionocytes: 3011.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 2666.5" "Group enriched" "Detected in some" 12 "cerebral cortex: 24.5;pons: 14.5;thalamus: 39.8" "Immune cell enriched" "Detected in some" 1026 "neutrophil: 1774.5" "Lineage enriched" "Detected in single" 4390 "granulocytes: 1774.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 544.0;prostate cancer: 235.4" "Colon - Colon enterocytes" "CAB009449, HPA017737" Enhanced Approved "Plasma membrane" "Secreted to blood" "Enzyme inhibitor" NA NA 1400000 "Cluster 4: Neutrophils - Degranulation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" "CAB009449: AB_2252354, HPA017737: AB_1848107" "prognostic favorable (6.94e-4)" "unprognostic (3.61e-2)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (7.34e-2)" "unprognostic (1.85e-1)" "unprognostic (3.20e-3)" "unprognostic (5.53e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.84e-6)" "prognostic unfavorable (6.89e-4)" "unprognostic (8.54e-3)" "prognostic unfavorable (1.94e-8)" "unprognostic (1.23e-1)" "unprognostic (7.38e-2)" "unprognostic (1.04e-2)" "unprognostic (5.91e-3)" PIANP "C12orf53, DKFZp547D2210, PANP" ENSG00000139200 "PILR alpha associated neural protein" Q8IYJ0 12 6693791-6700815 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 142.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.0;Excitatory neurons: 23.6;Horizontal cells: 27.1;Inhibitory neurons: 22.9;Oligodendrocyte precursor cells: 15.1;Peritubular cells: 13.9" "Group enriched" "Detected in many" 4 "glioma: 14.7;testis cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 30.4" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010631 Enhanced Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 4 Nucleoplasm "HPA010631: AB_10603680" "unprognostic (1.82e-1)" "unprognostic (9.21e-3)" "unprognostic (1.62e-2)" "unprognostic (7.65e-2)" "unprognostic (1.34e-1)" "unprognostic (3.03e-2)" "unprognostic (6.58e-2)" "unprognostic (1.07e-1)" "unprognostic (1.70e-1)" "unprognostic (6.41e-3)" "unprognostic (1.92e-2)" "unprognostic (3.89e-1)" "unprognostic (3.30e-3)" "unprognostic (3.26e-3)" "unprognostic (1.16e-1)" "unprognostic (2.30e-1)" "unprognostic (2.34e-2)" PIBF1 "C13orf24, CEP90, PIBF" ENSG00000083535 "Progesterone immunomodulatory binding factor 1" Q8WXW3 13 72782133-73016461 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 359.5;Oligodendrocyte precursor cells: 134.9;Oligodendrocytes: 129.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052269, HPA066120" Approved Supported "Centriolar satellite" "Secreted to blood" Immunity NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" 3 "Centriolar satellite" "HPA052269: AB_2681779, HPA066120: AB_2685621" "unprognostic (1.54e-1)" "unprognostic (4.17e-1)" "unprognostic (6.73e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (3.80e-2)" "unprognostic (3.79e-2)" "unprognostic (3.87e-2)" "unprognostic (4.08e-2)" "unprognostic (2.62e-2)" "unprognostic (2.26e-3)" "unprognostic (1.39e-1)" "unprognostic (6.85e-3)" "unprognostic (8.31e-2)" "unprognostic (2.78e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-1)" PIGK "GPI8, hGPI8" ENSG00000142892 "Phosphatidylinositol glycan anchor biosynthesis class K" Q92643 1 77088989-77219430 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Hydrolase, Protease, Thiol protease" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056383, HPA057040" Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 2 "HPA056383: AB_2683109, HPA057040: AB_2683319" "unprognostic (2.43e-2)" "unprognostic (2.60e-1)" "unprognostic (4.07e-2)" "unprognostic (2.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (1.07e-1)" "unprognostic (5.19e-1)" "unprognostic (1.12e-1)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (1.76e-2)" "unprognostic (3.37e-1)" "unprognostic (1.38e-1)" "unprognostic (1.21e-1)" "unprognostic (8.12e-3)" PIGL ENSG00000108474 "Phosphatidylinositol glycan anchor biosynthesis class L" Q9Y2B2 17 16217191-16351797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "GPI-anchor biosynthesis, Lipid metabolism" Hydrolase "Deafness, Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 45.1;Inhibitory neurons: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012739 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 53: Non-specific - Glycosylation" "Cluster 31: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 8: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA012739: AB_1855367" "unprognostic (3.07e-2)" "unprognostic (2.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-2)" "unprognostic (7.70e-2)" "unprognostic (6.14e-2)" "unprognostic (9.39e-5)" "unprognostic (1.11e-2)" "unprognostic (1.15e-2)" "unprognostic (1.63e-2)" "unprognostic (6.37e-3)" "prognostic unfavorable (2.57e-4)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.19e-2)" "unprognostic (2.13e-1)" "unprognostic (3.38e-1)" "unprognostic (2.75e-3)" PIGR ENSG00000162896 "Polymeric immunoglobulin receptor" P01833 1 206928522-206946466 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2560.5;salivary gland: 1591.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 9136.7;Enteroendocrine cells: 1484.9;Intestinal goblet cells: 1895.6;Paneth cells: 2797.4;Proximal enterocytes: 1597.7;Serous glandular cells: 1581.6;Undifferentiated cells: 3247.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 731.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 29.7;colorectal cancer: 30.9;Gastric cancer: 55.5" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA006154, CAB009454, HPA012012" Enhanced "Secreted to digestive system" "No annotated function" NA NA 1300000000 "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "CAB009454: AB_2164819, HPA006154: AB_1855370, HPA012012: AB_1855371" "prognostic favorable (1.22e-5)" "unprognostic (7.42e-2)" "unprognostic (4.78e-3)" "prognostic favorable (2.57e-4)" "unprognostic (2.31e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (2.13e-1)" "prognostic favorable (5.08e-5)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (6.92e-3)" "unprognostic (3.39e-2)" PIGT ENSG00000124155 "Phosphatidylinositol glycan anchor biosynthesis class T" Q969N2 20 45416084-45456934 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Other NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 53: Fibroblasts - ECM organization" 4 "unprognostic (6.06e-2)" "unprognostic (4.60e-3)" "unprognostic (7.63e-2)" "unprognostic (6.00e-2)" "unprognostic (6.18e-3)" "unprognostic (6.68e-2)" "unprognostic (7.34e-3)" "unprognostic (1.17e-1)" "unprognostic (2.70e-2)" "unprognostic (3.32e-1)" "prognostic favorable (2.51e-4)" "unprognostic (5.48e-2)" "unprognostic (7.60e-2)" "unprognostic (9.21e-2)" "unprognostic (5.66e-2)" "unprognostic (1.06e-1)" "unprognostic (3.43e-2)" PIK3AP1 "BCAP, FLJ35564" ENSG00000155629 "Phosphoinositide-3-kinase adaptor protein 1" Q6ZUJ8 10 96593315-96720514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 80.7;lymphoid tissue: 60.6;salivary gland: 71.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 63.9;Hofbauer cells: 62.8;Kupffer cells: 138.7;Macrophages: 95.5;Microglial cells: 58.2;monocytes: 136.4;Serous glandular cells: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 44.6;memory B-cell: 48.4;naive B-cell: 44.6;non-classical monocyte: 123.7" "Group enriched" "Detected in all" 6 "B-cells: 48.4;monocytes: 123.7" "Cancer enhanced" "Detected in many" "Leukemia: 54.3;lymphoma: 97.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026136, HPA038452" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" No No "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 1 Cytosol "Nucleoplasm, Plasma membrane" "CAB026136: , HPA038452: AB_2676019" "unprognostic (2.83e-2)" "unprognostic (4.61e-3)" "unprognostic (7.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.79e-1)" "unprognostic (1.49e-1)" "unprognostic (4.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" "unprognostic (2.10e-1)" "unprognostic (5.11e-2)" "unprognostic (1.28e-1)" "unprognostic (4.69e-2)" "unprognostic (5.45e-1)" "unprognostic (1.13e-1)" PILRA FDF03 ENSG00000085514 "Paired immunoglobin like type 2 receptor alpha" Q9UKJ1 7 100367530-100400096 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 129.9;Kupffer cells: 84.8;Langerhans cells: 82.8;Macrophages: 124.2;monocytes: 429.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1664.4;non-classical monocyte: 1150.6" "Group enriched" "Detected in all" 5 "granulocytes: 1664.4;monocytes: 1150.6" "Cancer enhanced" "Detected in some" "Leukemia: 6.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" HPA056132 Approved "Secreted to blood" Receptor NA NA 1500000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 2 "HPA056132: AB_2683048" "unprognostic (5.53e-2)" "prognostic favorable (2.99e-4)" "unprognostic (7.61e-2)" "unprognostic (2.88e-1)" "unprognostic (2.20e-1)" "unprognostic (5.88e-2)" "unprognostic (1.44e-1)" "unprognostic (2.85e-1)" "unprognostic (3.01e-3)" "unprognostic (9.95e-2)" "unprognostic (8.57e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (3.47e-2)" "unprognostic (3.17e-2)" "unprognostic (1.99e-1)" "unprognostic (4.80e-2)" PILRB "FDFACT1, FDFACT2" ENSG00000121716 "Paired immunoglobin like type 2 receptor beta" Q9UKJ0 7 100352176-100367831 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 30.7;NK-cells: 57.1;Rod photoreceptor cells: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 251.7" "Group enriched" "Detected in all" 8 "granulocytes: 251.7;monocytes: 76.0" "Low cancer specificity" "Detected in all" HPA026750 Approved Approved Mitochondria "Intracellular and membrane" Receptor NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 19: NK-cells - Adaptive immune response" Mitochondria "HPA026750: AB_10670828" "unprognostic (8.33e-3)" "unprognostic (9.31e-2)" "unprognostic (1.32e-2)" "unprognostic (9.15e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (3.17e-1)" "unprognostic (1.20e-1)" "unprognostic (8.76e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.85e-3)" "unprognostic (1.66e-1)" "unprognostic (4.40e-2)" "unprognostic (3.35e-3)" PINLYP ENSG00000234465 "Phospholipase A2 inhibitor and LY6/PLAUR domain containing" A6NC86 19 43575801-43583964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 33.8;Proximal tubular cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 21.1" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 20.8" "Heart muscle - Fibroblasts" "Not detected" "Not detected" HPA061218 Uncertain Approved Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Neuronal - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" Vesicles "HPA061218: AB_2684453" "unprognostic (6.72e-2)" "unprognostic (6.21e-2)" "unprognostic (4.72e-1)" "unprognostic (3.13e-2)" "unprognostic (2.46e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-2)" "unprognostic (5.07e-2)" "unprognostic (2.00e-1)" "unprognostic (2.85e-2)" "unprognostic (1.14e-1)" "unprognostic (4.36e-3)" "unprognostic (1.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "unprognostic (3.60e-2)" PIP "BRST-2, GCDFP-15, GCDFP15, GPIP4, SABP" ENSG00000159763 "Prolactin induced protein" P12273 7 143132077-143139739 "Plasma proteins, Predicted secreted proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "salivary gland: 16308.1" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 6511.8;Serous glandular cells: 3978.8" "Cancer enriched" "Detected in many" 70 "breast cancer: 672.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 161 "breast cancer: 113.7" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002661, HPA009177" Enhanced "Secreted in other tissues" Other NA NA 66000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" "CAB002661: , HPA009177: AB_1845459" "unprognostic (2.80e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-3)" "unprognostic (3.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.14e-1)" "unprognostic (3.49e-2)" "unprognostic (5.55e-1)" PKDCC "SgK493, Vlk" ENSG00000162878 "Protein kinase domain containing, cytoplasmic" Q504Y2 2 42048021-42058517 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Differentiation, Osteogenesis, Protein transport, Transport" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 82.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 69.6;Leydig cells: 130.6;Peritubular cells: 107.9;Rod photoreceptor cells: 96.8;Skeletal myocytes: 106.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 59.6" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026427, HPA026442, HPA026526" Approved "Secreted to blood" Transport NA NA 80000 "Cluster 19: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA026427: AB_10600773, HPA026442: AB_10601237, HPA026526: AB_10602416" "unprognostic (6.77e-2)" "unprognostic (3.35e-1)" "unprognostic (1.04e-2)" "unprognostic (3.59e-3)" "unprognostic (8.31e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-2)" "unprognostic (5.79e-3)" "unprognostic (1.04e-2)" "unprognostic (1.32e-1)" "unprognostic (3.20e-1)" "unprognostic (6.09e-2)" "unprognostic (2.14e-2)" "unprognostic (9.08e-2)" "unprognostic (2.62e-1)" "unprognostic (4.73e-3)" "unprognostic (2.58e-3)" PKHD1 "ARPKD, FCYT, FPC, TIGM1" ENSG00000170927 "PKHD1 ciliary IPT domain containing fibrocystin/polyductin" P08F94 6 51615299-52087613 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.6;kidney: 13.2;pancreas: 9.1" "Group enriched" "Detected in some" 5 "Early spermatids: 370.0;Late spermatids: 97.9" "Group enriched" "Detected in some" 5 "pancreatic cancer: 1.4;renal cancer: 5.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.1;Kidney cancer: 2.0" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031227 Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" 1 "HPA031227: AB_10602068" "unprognostic (6.34e-3)" "unprognostic (5.51e-2)" "unprognostic (8.80e-3)" "unprognostic (1.35e-1)" "unprognostic (3.80e-2)" "unprognostic (1.29e-2)" "unprognostic (4.03e-2)" "unprognostic (6.42e-2)" "unprognostic (7.08e-2)" "unprognostic (2.44e-2)" "unprognostic (1.02e-2)" "unprognostic (2.62e-2)" "prognostic favorable (9.74e-8)" "unprognostic (2.33e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.48e-2)" PLA1A ps-PLA1 ENSG00000144837 "Phospholipase A1 member A" Q53H76 3 119597875-119629811 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 88.2;epididymis: 135.1;parathyroid gland: 63.7;seminal vesicle: 64.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 70.5;Collecting duct cells: 19.4;Endothelial cells: 16.2;Hepatocytes: 22.9;Langerhans cells: 19.7;Peritubular cells: 13.5;Skeletal myocytes: 14.6" "Group enriched" "Detected in many" 5 "liver cancer: 14.8;melanoma: 55.4;prostate cancer: 24.2;renal cancer: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 22.8;skin cancer: 34.7" "Breast - Endothelial cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059740 Approved "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" "Secreted in other tissues" Enzyme NA NA 420000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 3: Basal prostatic cells - Lipid metabolism" "Nuclear speckles, Cytoplasmic bodies" Nucleoplasm "HPA059740: AB_2684118" "unprognostic (1.35e-1)" "prognostic favorable (2.81e-7)" "unprognostic (2.24e-2)" "unprognostic (3.46e-2)" "unprognostic (3.18e-2)" "unprognostic (1.94e-2)" "unprognostic (1.11e-2)" "unprognostic (2.43e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" "unprognostic (9.09e-2)" "unprognostic (1.55e-3)" "unprognostic (9.53e-3)" "unprognostic (3.94e-2)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" PLA2G10 GXPLA2 ENSG00000069764 "Phospholipase A2 group X" O15496 16 14672548-14694308 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 26.2;stomach 1: 40.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 230.7;Enteroendocrine cells: 55.2;Exocrine glandular cells: 52.6;Extravillous trophoblasts: 64.7;Gastric mucus-secreting cells: 73.7;Intestinal goblet cells: 144.6;Paneth cells: 68.2" "Cancer enhanced" "Detected in many" "stomach cancer: 6.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.0;Gastric cancer: 4.1;pancreatic cancer: 4.4" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041893 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 40 "HPA041893: AB_10794495" "unprognostic (8.44e-3)" "unprognostic (2.37e-1)" "unprognostic (6.72e-2)" "prognostic favorable (5.74e-5)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (5.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.77e-2)" "unprognostic (2.72e-1)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.08e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-2)" "unprognostic (9.97e-3)" PLA2G12A PLA2G12 ENSG00000123739 "Phospholipase A2 group XIIA" Q9BZM1 4 109709989-109730070 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035908, HPA035909" Approved "Secreted to blood" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 57: Platelets - Hemostasis" 2 "HPA035908: AB_2674856, HPA035909: AB_10672074" "unprognostic (8.40e-2)" "unprognostic (3.87e-1)" "unprognostic (3.81e-3)" "unprognostic (3.09e-2)" "unprognostic (2.10e-1)" "unprognostic (1.35e-1)" "unprognostic (4.26e-2)" "unprognostic (1.77e-1)" "unprognostic (1.90e-1)" "unprognostic (2.71e-3)" "unprognostic (1.02e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.54e-9)" "unprognostic (3.10e-1)" "unprognostic (1.39e-1)" "unprognostic (9.16e-3)" "unprognostic (3.64e-2)" PLA2G12B PLA2G13 ENSG00000138308 "Phospholipase A2 group XIIB" Q9BX93 10 72934762-72954806 "Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 32.1;kidney: 13.8;liver: 68.8" "Group enriched" "Detected in some" 5 "Early spermatids: 19.2;Hepatocytes: 50.1;Proximal enterocytes: 72.0" "Cancer enriched" "Detected in many" 8 "liver cancer: 35.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "liver cancer: 7.1" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA057745, HPA059562" Approved "Secreted to blood" "No annotated function" NA NA 2300000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 1: Neuronal - Visual perception" "Cluster 22: Proximal enterocytes - Digestion" "HPA057745: AB_2683514, HPA059562: AB_2684064" "unprognostic (1.11e-2)" "unprognostic (2.66e-2)" "unprognostic (2.02e-3)" "unprognostic (3.41e-1)" "unprognostic (1.68e-1)" "unprognostic (1.89e-1)" "unprognostic (1.26e-1)" "unprognostic (3.14e-2)" PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 56.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 103.4;Syncytiotrophoblasts: 45.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Lung - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 38000000 "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 58: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" PLA2G1B "PLA2, PLA2A, PPLA2" ENSG00000170890 "Phospholipase A2 group IB" P04054 12 120322115-120327779 "Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 2908 "pancreas: 113918.1" "Cell type enriched" "Detected in some" 39 "Exocrine glandular cells: 9563.7" "Cancer enriched" "Detected in many" 185 "pancreatic cancer: 763.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Alveolar cells type 2, Pancreas - Exocrine glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047822, HPA060803" Enhanced "Secreted to digestive system" Enzyme NA NA 3900000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 15: Pancreas - Proteolysis" "Cluster 7: Liver cancer - Metabolism" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA047822: AB_2680169, HPA060803: AB_2684369" "unprognostic (1.28e-4)" "unprognostic (6.02e-2)" "unprognostic (1.84e-2)" "unprognostic (2.86e-2)" "unprognostic (2.74e-2)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.63e-2)" "unprognostic (3.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (2.80e-4)" "unprognostic (2.15e-1)" "unprognostic (1.97e-1)" "unprognostic (3.60e-1)" "unprognostic (8.61e-4)" PLA2G2A "PLA2B, PLA2L" ENSG00000188257 "Phospholipase A2 group IIA" P14555 1 19975431-19980416 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" "Antimicrobial, Bacteriolytic enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 904.0;intestine: 1462.3;placenta: 558.1;urinary bladder: 630.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 640.8;Exocrine glandular cells: 430.1;Fibroblasts: 1056.7;Mesothelial cells: 1444.4;Proximal enterocytes: 427.4;Undifferentiated cells: 2509.4" "Cancer enhanced" "Detected in all" "prostate cancer: 875.7" "Region enhanced" "Detected in some" "choroid plexus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 84.8;Gastric cancer: 164.6" "Colon - Macrophages, Lung - Fibroblast_2, Thyroid - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" HPA015236 Enhanced "Secreted to blood" Enzyme NA NA 1000000 680000 "Cluster 45: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA015236: AB_10601047" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (2.79e-2)" "unprognostic (7.85e-3)" "unprognostic (8.71e-2)" "unprognostic (9.27e-2)" "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "prognostic favorable (1.49e-4)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.77e-15)" "unprognostic (2.72e-2)" "unprognostic (9.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.51e-1)" PLA2G2C UBXN10-AS1 ENSG00000187980 "Phospholipase A2 group IIC" Q5R387 1 20161253-20186518 "Predicted secreted proteins, RAS pathway related proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "intestine: 1.2" "Cell type enhanced" "Detected in many" "Early spermatids: 14.3;Glandular and luminal cells: 11.7;granulocytes: 20.5;Late spermatids: 26.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" "No annotated function" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Granulocytes - Unknown function" "unprognostic (3.02e-3)" "unprognostic (2.75e-2)" "unprognostic (5.76e-2)" "unprognostic (3.00e-4)" "unprognostic (9.44e-3)" "unprognostic (6.55e-3)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "unprognostic (3.92e-1)" "unprognostic (1.80e-1)" "unprognostic (1.46e-1)" "unprognostic (1.22e-2)" "unprognostic (4.84e-2)" "unprognostic (1.67e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (8.16e-2)" PLA2G2D sPLA2S ENSG00000117215 "Phospholipase A2 group IID" Q9UNK4 1 20111939-20119566 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 103.9" "Cell type enriched" "Detected in some" 6 "Plasma cells: 15.7" "Cancer enriched" "Detected in many" 6 "testis cancer: 25.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 3.7;naive B-cell: 3.7;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 6 "B-cells: 3.7;dendritic cells: 2.0" "Group enriched" "Detected in some" 7 "lymphoma: 2.0;Myeloma: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" Enzyme NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 77: Plasma cells - Protein processing" "prognostic favorable (4.35e-4)" "prognostic favorable (8.15e-5)" "unprognostic (3.88e-3)" "prognostic favorable (9.74e-4)" "unprognostic (1.78e-1)" "unprognostic (2.56e-3)" "unprognostic (1.98e-1)" "unprognostic (1.60e-2)" "unprognostic (1.82e-5)" "unprognostic (7.51e-4)" "unprognostic (2.50e-2)" "unprognostic (1.22e-1)" "unprognostic (4.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.85e-1)" "unprognostic (8.08e-2)" "unprognostic (2.60e-1)" PLA2G2E ENSG00000188784 "Phospholipase A2 group IIE" Q9NZK7 1 19920009-19923617 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "lymphoid tissue: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA064085 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 32: Non-specific - Cell proliferation" 1 "HPA064085: AB_2685188" "unprognostic (9.56e-2)" "unprognostic (3.71e-2)" PLA2G2F ENSG00000158786 "Phospholipase A2 group IIF" Q9BZM2 1 20139323-20150381 "Enzymes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Innate immunity, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 25 "lymphoid tissue: 7.8;skin 1: 14.4;urinary bladder: 11.4" "Cell type enhanced" "Detected in some" "Club cells: 2.0;Collecting duct cells: 1.9" "Cancer enriched" "Detected in some" 18 "urothelial cancer: 17.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Bladder cancer: 6.8" "Region enriched" "Detected in single" 4 "hippocampal formation: 3.0" "Not detected" "Not detected" "Intracellular and membrane" Immunity NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-2)" "unprognostic (1.79e-2)" "unprognostic (5.11e-2)" "unprognostic (4.63e-2)" "unprognostic (4.83e-2)" "unprognostic (1.51e-1)" "unprognostic (1.61e-2)" "unprognostic (3.36e-5)" "unprognostic (7.06e-2)" "unprognostic (1.84e-1)" "unprognostic (4.69e-1)" "prognostic favorable (3.86e-4)" PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134807-31140508 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid metabolism, Mast cell degranulation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 13.4;skin 1: 14.9;vagina: 6.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 17.9;Basal keratinocytes: 4.1;Breast glandular cells: 7.5;Suprabasal keratinocytes: 20.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 11.5" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021016 Uncertain Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 17: Breast glandular cells - Lactation" "Golgi apparatus" "Endoplasmic reticulum" "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" PLA2G5 ENSG00000127472 "Phospholipase A2 group V" P39877 1 20028179-20091911 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism, Phagocytosis, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 57.3;heart muscle: 128.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 87.9;Cone photoreceptor cells: 149.5;Leydig cells: 82.7;Ovarian stromal cells: 52.3;Peritubular cells: 78.1;Sertoli cells: 108.8" "Group enriched" "Detected in many" 5 "glioma: 13.0;prostate cancer: 3.5" "Region enhanced" "Detected in all" "choroid plexus: 32.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA053361 Approved "Secreted in other tissues" Enzyme NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 72: Neuronal - Signal transduction" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA053361: AB_2682127" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (5.68e-3)" "unprognostic (6.16e-2)" "unprognostic (2.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.70e-3)" "unprognostic (6.00e-5)" "unprognostic (2.87e-2)" "unprognostic (3.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.97e-3)" PLA2G7 "LDL-PLA2, PAFAH" ENSG00000146070 "Phospholipase A2 group VII" Q13093 6 46704201-46735693 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Asthma, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 26.5;placenta: 22.5" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 328.4" "Cancer enhanced" "Detected in all" "prostate cancer: 37.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 43.4" "Group enriched" "Detected in many" 53 "dendritic cells: 14.1;monocytes: 43.4" "Cancer enriched" "Detected in some" 8 "prostate cancer: 15.1" "Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 7380000 290000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 60: Prostate cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" "unprognostic (3.63e-3)" "unprognostic (2.82e-3)" "unprognostic (8.69e-2)" "unprognostic (3.00e-1)" "unprognostic (1.47e-1)" "unprognostic (6.26e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.43e-1)" "unprognostic (2.06e-2)" "unprognostic (5.33e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "unprognostic (9.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 38.0;thyroid gland: 40.6" "Cell type enhanced" "Detected in many" "Serous glandular cells: 142.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Podocytes, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" Receptor NA NA 960000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" PLAC1 "CT92, OOSP2B, OOSP2L" ENSG00000170965 "Placenta enriched 1" Q9HBJ0 X 134565838-134764322 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "placenta: 27.0" "Group enriched" "Detected in some" 4 "Leydig cells: 5.4;Peritubular cells: 8.4;Smooth muscle cells: 13.4;Spermatocytes: 10.8;Spermatogonia: 6.7;Syncytiotrophoblasts: 12.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000163, HPA063425" Enhanced Approved Vesicles,Cytosol "Secreted in female reproductive system" "Developmental protein" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 50: Connective tissue cells - ECM organization" Vesicles Cytosol "HPA000163: , HPA063425: AB_2685012" "unprognostic (2.93e-1)" "unprognostic (2.50e-3)" "unprognostic (2.89e-4)" "unprognostic (1.35e-7)" "unprognostic (3.83e-3)" "unprognostic (2.07e-2)" "unprognostic (1.63e-2)" "unprognostic (1.26e-1)" "unprognostic (2.01e-1)" "unprognostic (4.28e-2)" "unprognostic (1.48e-2)" "unprognostic (2.87e-2)" "unprognostic (3.33e-16)" "unprognostic (7.64e-3)" "unprognostic (4.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.91e-2)" PLAC9 ENSG00000189129 "Placenta associated 9" Q5JTB6 10 80131682-80145359 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 222.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 772.1;Leydig cells: 832.0;Peritubular cells: 626.1;Smooth muscle cells: 479.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 104.4" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 50.7" HPA043469 Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 3 "HPA043469: AB_10795770" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (5.01e-3)" "unprognostic (1.78e-2)" "unprognostic (2.76e-1)" "unprognostic (3.93e-1)" "unprognostic (5.57e-3)" "unprognostic (5.88e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-3)" "unprognostic (4.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.14e-1)" "unprognostic (2.82e-3)" PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 237.9;urinary bladder: 174.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 133.4;Breast glandular cells: 99.1;Endometrial stromal cells: 101.4;Endothelial cells: 108.9;Fibroblasts: 93.6;granulocytes: 135.2;Lymphatic endothelial cells: 87.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 246.4" "Kidney - Endothelial cells, Prostate - Urothelial cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" Enzyme NA NA 9900000 110000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917496 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 101.0;urinary bladder: 123.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 212.1;Collecting duct cells: 89.5;Ionocytes: 129.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 1.1;neutrophil: 2.1;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 11 "dendritic cells: 2.0;granulocytes: 2.1" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1199.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070796 Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Blood coagulation" NA NA 647000 88000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Golgi apparatus, Vesicles" "HPA070796: " "unprognostic (1.96e-2)" "unprognostic (2.99e-2)" "unprognostic (7.40e-2)" "prognostic favorable (3.38e-4)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (1.39e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.26e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" PLAUR "CD87, UPAR, URKR" ENSG00000011422 "Plasminogen activator, urokinase receptor" Q03405 19 43646095-43670547 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 680.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 806.7;Langerhans cells: 2298.1;Macrophages: 885.5;monocytes: 3085.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1177.3" "Group enriched" "Detected in all" 4 "granulocytes: 1177.3;monocytes: 553.8" "Low cancer specificity" "Detected in all" "Thyroid - Neutrophils" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050843, CAB073533" Uncertain Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 4100000 "Cluster 7: Non-specific - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 29: Monocytes - Innate immune response" 1 "Plasma membrane" "CAB073533: , HPA050843: AB_2681255" "unprognostic (9.28e-2)" "unprognostic (9.65e-3)" "unprognostic (1.39e-1)" "unprognostic (1.29e-3)" "unprognostic (3.59e-3)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "prognostic unfavorable (2.33e-5)" "unprognostic (8.08e-3)" "unprognostic (4.30e-2)" "unprognostic (2.29e-3)" "unprognostic (5.30e-2)" "prognostic unfavorable (7.83e-9)" "unprognostic (4.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.45e-2)" "unprognostic (9.33e-2)" PLBD1 FLJ22662 ENSG00000121316 "Phospholipase B domain containing 1" Q6P4A8 12 14503661-14567883 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 283.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 207.6;Hofbauer cells: 133.2;Kupffer cells: 129.3;Macrophages: 113.1;Paneth cells: 115.1" "Cancer enhanced" "Detected in all" "testis cancer: 113.6" "Region enriched" "Detected in all" 6 "choroid plexus: 51.0" "Group enriched" "Detected in many" 6 "classical monocyte: 663.4;intermediate monocyte: 204.4;myeloid DC: 357.5;neutrophil: 445.2" "Group enriched" "Detected in all" 135 "dendritic cells: 357.5;granulocytes: 445.2;monocytes: 663.4" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040303 Enhanced "Intracellular and membrane" Enzyme NA NA 3400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" "HPA040303: AB_2676922" "unprognostic (9.13e-3)" "unprognostic (5.77e-2)" "unprognostic (2.29e-1)" "unprognostic (7.87e-2)" "unprognostic (1.71e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (4.80e-2)" "unprognostic (1.85e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.12e-1)" "unprognostic (3.03e-3)" "unprognostic (3.47e-1)" "unprognostic (1.97e-1)" "unprognostic (4.99e-2)" "unprognostic (5.44e-2)" PLBD2 p76 ENSG00000151176 "Phospholipase B domain containing 2" Q8NHP8 12 113358566-113391629 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 134.6" "Group enriched" "Detected in many" 5 "Early spermatids: 103.8;Late spermatids: 386.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017163 Approved "Intracellular and membrane" Enzyme NA NA 820000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 36: Late spermatids - Unknown function" 1 "HPA017163: AB_1853029" "unprognostic (8.28e-2)" "unprognostic (1.97e-1)" "unprognostic (1.50e-2)" "unprognostic (4.13e-1)" "unprognostic (2.36e-3)" "unprognostic (7.59e-3)" "unprognostic (5.92e-3)" "unprognostic (2.39e-2)" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.58e-11)" "unprognostic (7.55e-3)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" "unprognostic (5.48e-2)" PLG ENSG00000122194 Plasminogen P00747 6 160702194-160754097 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Tissue remodeling" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 2571.0" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 1618.7" "Cancer enriched" "Detected in some" 84 "liver cancer: 180.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 2.6" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000668, CAB016678, HPA021602, HPA048823, HPA053770" Supported Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 140000000000 45000000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 2 Vesicles "CAB000668: , CAB016678: AB_1621208, HPA021602: AB_1855453, HPA048823: AB_2680532, HPA053770: AB_2682256" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.44e-1)" "unprognostic (8.54e-3)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (6.28e-2)" "unprognostic (7.25e-2)" "prognostic favorable (4.22e-4)" "unprognostic (3.97e-3)" "unprognostic (5.21e-2)" "unprognostic (2.33e-2)" PLGLB1 "PLGL, PRP-B" ENSG00000183281 "Plasminogen like B1" Q02325 2 87002559-87021852 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 61.5;liver: 229.3" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 62.1" "Cancer enriched" "Detected in single" 7 "liver cancer: 0.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" HPA053770 Approved Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 32: Basophils - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 62: Hepatocytes - Metabolism" Vesicles "HPA053770: AB_2682256" "unprognostic (7.25e-2)" "unprognostic (7.25e-2)" "unprognostic (2.35e-1)" "unprognostic (1.15e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-5)" "unprognostic (7.04e-3)" "unprognostic (1.15e-1)" "unprognostic (8.53e-4)" "unprognostic (1.60e-1)" "unprognostic (4.56e-4)" "unprognostic (9.90e-3)" "unprognostic (2.96e-5)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (4.32e-2)" "unprognostic (3.98e-5)" PLGLB2 PLGP1 ENSG00000125551 "Plasminogen like B2" Q02325 2 87748087-87759476 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 165 "liver: 443.3" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 66.2" "Cancer enriched" "Detected in single" 25 "liver cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA053770 Approved Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 43: Hepatocytes - Metabolism" Vesicles "HPA053770: AB_2682256" "unprognostic (1.10e-2)" "unprognostic (8.78e-2)" "unprognostic (3.42e-2)" "unprognostic (7.03e-4)" "unprognostic (1.68e-2)" "unprognostic (3.77e-1)" "unprognostic (1.82e-2)" "unprognostic (5.74e-2)" "unprognostic (2.94e-1)" "unprognostic (5.04e-4)" "unprognostic (6.39e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-2)" "unprognostic (7.11e-2)" PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 263.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 3600000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.43e-4)" PLOD2 "LH2, TLH" ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146035139-146163725 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 124.2;Extravillous trophoblasts: 149.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Kidney cancer: 285.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" Enzyme NA NA 21000 "Cluster 11: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavorable (7.64e-10)" "prognostic unfavorable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.99e-11)" "prognostic unfavorable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" PLOD3 LH3 ENSG00000106397 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3" O60568 7 101205977-101218420 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Dioxygenase, Glycosyltransferase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 79.5;Melanocytes: 89.3" "Cancer enhanced" "Detected in all" "melanoma: 115.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 20.3;monocytes: 22.6;T-cells: 12.6" "Cancer enhanced" "Detected in all" "skin cancer: 375.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075391 Approved "Secreted to extracellular matrix" Enzyme NA NA 1600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 7: Adipose tissue - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 12 "HPA075391: " "unprognostic (1.15e-1)" "prognostic unfavorable (1.91e-5)" "prognostic unfavorable (3.26e-4)" "unprognostic (1.39e-1)" "unprognostic (2.76e-3)" "unprognostic (1.04e-2)" "unprognostic (6.26e-3)" "unprognostic (1.11e-3)" "unprognostic (8.00e-3)" "unprognostic (1.18e-2)" "unprognostic (4.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.21e-3)" "unprognostic (1.68e-1)" "unprognostic (1.54e-1)" "unprognostic (8.52e-3)" "unprognostic (9.87e-2)" PLTP BPIFE ENSG00000100979 "Phospholipid transfer protein" P55058 20 45898621-45912155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1458.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 33.2;eosinophil: 29.6" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Rhabdoid: 187.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032873 Approved "Secreted to blood" Transport NA NA 9720000000 210000000 "Cluster 41: Basophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Macrophages - Innate immune response" "CAB032873: AB_2283977" "unprognostic (1.27e-1)" "unprognostic (3.50e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.72e-2)" "unprognostic (4.19e-2)" "unprognostic (8.30e-2)" "unprognostic (3.19e-2)" "unprognostic (2.65e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (9.52e-8)" "unprognostic (3.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.21e-1)" "unprognostic (9.68e-2)" PLXDC1 "TEM3, TEM7" ENSG00000161381 "Plexin domain containing 1" Q8IUK5 17 39063313-39154394 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 46.9" "Cell type enriched" "Detected in many" 4 "Bipolar cells: 272.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 13.9" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA012805 Approved "Intracellular and membrane" "No annotated function" NA NA 17000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 28: Neuronal - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 25: Bipolar cells - Visual perception" "HPA012805: AB_1857893" "unprognostic (4.28e-1)" "unprognostic (3.55e-1)" "unprognostic (2.56e-2)" "unprognostic (2.15e-1)" "unprognostic (9.50e-2)" "unprognostic (1.13e-2)" "unprognostic (2.35e-2)" "unprognostic (2.23e-2)" "unprognostic (4.07e-3)" "unprognostic (6.07e-3)" "unprognostic (4.62e-3)" "unprognostic (8.69e-2)" "prognostic unfavorable (9.15e-8)" "unprognostic (9.37e-3)" "unprognostic (1.72e-2)" "unprognostic (2.42e-1)" "unprognostic (2.33e-2)" PLXNA4 "DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B" ENSG00000221866 "Plexin A4" Q9HCM2 7 132123340-132648688 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.3" "Cell type enhanced" "Detected in many" "dendritic cells: 64.2;Excitatory neurons: 227.5;Inhibitory neurons: 251.3;Oligodendrocyte precursor cells: 48.6" "Cancer enhanced" "Detected in many" "glioma: 3.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.6" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 14.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029919, HPA052141, HPA075592" Approved Approved "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" "HPA029919: AB_10671093, HPA052141: AB_2681745, HPA075592: AB_2732297" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.61e-6)" "unprognostic (5.76e-2)" "unprognostic (1.21e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-2)" "unprognostic (2.19e-1)" "unprognostic (7.99e-2)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-5)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (5.90e-2)" "unprognostic (1.42e-3)" PLXNB1 "KIAA0407, PLXN5, SEP" ENSG00000164050 "Plexin B1" O43157 3 48403854-48430086 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 114.9;Oligodendrocytes: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040586 Enhanced "Intracellular and membrane" Receptor NA NA 95000000 "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Astrocytes - Unknown function" 5 "HPA040586: AB_10794034" "unprognostic (1.31e-3)" "unprognostic (7.09e-2)" "unprognostic (9.63e-2)" "unprognostic (8.13e-2)" "unprognostic (3.65e-1)" "prognostic favorable (5.03e-4)" "unprognostic (1.06e-1)" "unprognostic (4.29e-2)" "unprognostic (3.45e-2)" "unprognostic (1.01e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-2)" "prognostic favorable (2.77e-5)" "unprognostic (4.01e-2)" "unprognostic (1.61e-1)" "unprognostic (6.98e-2)" "prognostic favorable (7.60e-4)" PM20D1 "Cps1, FLJ32569" ENSG00000162877 "Peptidase M20 domain containing 1" Q6GTS8 1 205828025-205850132 "Enzymes, Predicted secreted proteins" "Lipid metabolism" "Hydrolase, Lyase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "pancreas: 75.5;skin 1: 32.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.1;Exocrine glandular cells: 9.1;Gastric mucus-secreting cells: 4.7;Inhibitory neurons: 3.3;Lymphatic endothelial cells: 2.8;Proximal tubular cells: 3.7" "Cancer enriched" "Detected in some" 32 "urothelial cancer: 30.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.2" "Lineage enriched" "Detected in single" 6 "T-cells: 2.2" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to digestive system" Enzyme NA NA 3300000 "Cluster 15: Pancreas - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (4.07e-2)" "unprognostic (4.83e-1)" "unprognostic (4.08e-3)" "unprognostic (1.17e-3)" "unprognostic (3.11e-1)" "unprognostic (1.20e-1)" "unprognostic (5.50e-2)" "unprognostic (5.81e-2)" "unprognostic (4.57e-2)" "unprognostic (7.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (1.68e-2)" PMCH MCH ENSG00000183395 "Pro-melanin concentrating hormone" P20382 12 102196459-102197833 "Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein, Hormone, Neuropeptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 691 "brain: 715.2" "Cell type enhanced" "Detected in single" "T-cells: 2.1" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.8" "Region enhanced" "Detected in many" "hypothalamus: 202.9;thalamus: 127.6" "Immune cell enriched" "Detected in some" 10 "T-reg: 9.6" "Lineage enriched" "Detected in single" 86 "T-cells: 9.6" "Low cancer specificity" "Detected in single" "Group enriched" "Detected in many" 129 "hypothalamus: 624.4;thalamus: 340.0" "Region enriched" "Detected in many" 32 "hypothalamus: 125.8" "HPA046055, HPA061884" Enhanced Supported "Secreted to blood" Hormone NA NA 274000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA046055: AB_2679517, HPA061884: AB_2684632" "unprognostic (3.23e-3)" "unprognostic (8.04e-2)" "unprognostic (3.96e-4)" "unprognostic (2.09e-2)" "unprognostic (1.75e-1)" "unprognostic (7.73e-2)" "unprognostic (4.31e-3)" "unprognostic (1.43e-2)" "unprognostic (3.18e-3)" "unprognostic (4.51e-2)" "unprognostic (1.21e-1)" "unprognostic (2.16e-6)" "unprognostic (1.17e-2)" "unprognostic (1.93e-1)" "unprognostic (5.10e-2)" "unprognostic (3.53e-2)" PMEL "D12S53E, gp100, HMB-45, HMB45, ME20, Pmel17, SI, SIL, SILV" ENSG00000185664 "Premelanosome protein" P40967 12 55954105-55973317 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "cervix: 78.0;endometrium 1: 31.2;skin 1: 112.3" "Cell type enriched" "Detected in many" 61 "Melanocytes: 2210.9" "Cancer enriched" "Detected in many" 500 "melanoma: 2481.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 49 "skin cancer: 3389.1" "Liver - Hepatocytes, Skin - Melanocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA031649 Enhanced Supported "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" Other NA NA 11000000 "Cluster 13: Skin - Cornification" "Cluster 15: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "Endoplasmic reticulum" "Golgi apparatus" "HPA031649: AB_2673976" "unprognostic (4.63e-1)" "unprognostic (8.93e-2)" "unprognostic (1.53e-1)" "unprognostic (1.60e-1)" "unprognostic (5.90e-2)" "unprognostic (6.46e-2)" "unprognostic (1.94e-1)" "unprognostic (1.46e-3)" "unprognostic (6.44e-2)" "unprognostic (1.21e-1)" "unprognostic (5.12e-2)" "unprognostic (3.98e-1)" "prognostic favorable (3.70e-4)" "unprognostic (2.86e-2)" "unprognostic (1.54e-1)" "unprognostic (7.60e-2)" "unprognostic (1.04e-1)" PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 106.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 287.9;dendritic cells: 258.7;Ductal cells: 322.4;Muller glia cells: 312.7;Prostatic glandular cells: 636.7" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Colon - Enteric glia cells, Prostate - Prostate glandular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" Other NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" PMP22 "CMT1A, GAS3, HMSNIA, HNPP, Sp110" ENSG00000109099 "Peripheral myelin protein 22" Q01453 17 15229773-15272292 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes, Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 347.6;Hofbauer cells: 498.1;Leydig cells: 336.5;Melanocytes: 566.9;Proximal enterocytes: 708.2;Schwann cells: 1057.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 32.3;eosinophil: 43.1;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 22 "dendritic cells: 23.9;granulocytes: 43.1" "Group enriched" "Detected in many" 5 "Adrenocortical cancer: 276.5;Brain cancer: 135.3;Rhabdoid: 121.6;skin cancer: 209.0;testis cancer: 307.6" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 1023.1" "Intracellular and membrane" "No annotated function" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 52 "unprognostic (3.00e-1)" "unprognostic (1.65e-1)" "unprognostic (2.21e-1)" "unprognostic (4.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.28e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-1)" "unprognostic (4.33e-2)" "unprognostic (7.70e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.83e-2)" "unprognostic (5.45e-2)" "unprognostic (2.88e-1)" "unprognostic (1.08e-2)" PNLIP PL ENSG00000175535 "Pancreatic lipase" P16233 10 116545931-116567855 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4811 "pancreas: 430750.5" "Cell type enriched" "Detected in some" 15 "Exocrine glandular cells: 2323.2" "Cancer enriched" "Detected in some" 4854 "pancreatic cancer: 2731.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA062430, HPA062494" Enhanced "Secreted to digestive system" Enzyme NA NA 14000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 66: Non-specific - Mitochondria" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA062430: AB_2684761, HPA062494: AB_2684782" "unprognostic (2.05e-2)" "unprognostic (4.46e-2)" PNLIPRP1 PLRP1 ENSG00000187021 "Pancreatic lipase related protein 1" P54315 10 116590385-116609175 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3907 "pancreas: 10480.6" "Cell type enriched" "Detected in some" 19 "Exocrine glandular cells: 390.8" "Cancer enriched" "Detected in single" 476 "pancreatic cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" "No annotated function" NA NA 340000 "Cluster 15: Pancreas - Proteolysis" "Cluster 20: Myeloma - Immune response" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 31 "unprognostic (1.21e-1)" "unprognostic (4.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.80e-1)" "unprognostic (2.76e-2)" "unprognostic (1.41e-1)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" PNLIPRP3 ENSG00000203837 "Pancreatic lipase related protein 3" Q17RR3 10 116427847-116477957 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 8.8;skin 1: 14.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.0;Early spermatids: 1.8;Late spermatids: 1.8;Melanocytes: 1.7;Suprabasal keratinocytes: 3.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 4.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "head and neck cancer: 6.3;skin cancer: 2.3" "Skin - Sebaceous gland cells, Testis - Late spermatids" "Not detected" "Not detected" "HPA046202, HPA052009" Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA046202: AB_10959739, HPA052009: AB_2681692" "unprognostic (2.62e-4)" "unprognostic (1.60e-1)" "unprognostic (6.97e-2)" PNOC "N/OFQ, NOP, PPNOC" ENSG00000168081 Prepronociceptin Q13519 8 28316986-28343355 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Neuropeptide, Neurotransmitter, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 29.2;fallopian tube: 17.6;lymphoid tissue: 24.4" "Cell type enhanced" "Detected in some" "B-cells: 52.5;dendritic cells: 53.5;Inhibitory neurons: 22.3;Plasma cells: 90.7;Schwann cells: 19.4;Secretory cells: 50.2" "Cancer enriched" "Detected in many" 8 "ovarian cancer: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "memory B-cell: 232.1;naive B-cell: 261.7;plasmacytoid DC: 194.7" "Group enriched" "Detected in many" 20 "B-cells: 261.7;dendritic cells: 194.7" "Cancer enriched" "Detected in some" 11 "Rhabdoid: 338.9" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Thyroid - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044507, HPA056724" Enhanced "Secreted to blood" Neuropeptide NA NA 12300 "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 73: B-cells - B-cell function" "HPA044507: AB_10795043, HPA056724: AB_2683216" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.94e-6)" "unprognostic (3.71e-2)" "unprognostic (5.16e-5)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (7.81e-4)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" "unprognostic (7.57e-9)" "unprognostic (2.19e-2)" "unprognostic (5.45e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-1)" PNPLA4 "DXS1283E, GS2, iPLA2eta" ENSG00000006757 "Patatin like phospholipase domain containing 4" P41247 X 7898247-7927739 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" HPA003656 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 35: Non-specific - Mitochondria" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA003656: AB_1079033" "unprognostic (2.97e-1)" "unprognostic (2.45e-1)" "unprognostic (4.17e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.29e-4)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.15e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (6.30e-2)" "unprognostic (7.83e-2)" "unprognostic (2.27e-1)" "prognostic favorable (2.23e-12)" "unprognostic (5.23e-2)" "unprognostic (6.71e-3)" "unprognostic (6.30e-2)" "unprognostic (2.12e-1)" PODN "MGC24995, PCAN, PODOCAN, SLRR5A" ENSG00000174348 Podocan Q7Z5L7 1 53062052-53085501 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 164.9;Leydig cells: 268.7;Ovarian stromal cells: 59.6;Peritubular cells: 257.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "gdT-cell: 5.1;memory CD8 T-cell: 1.4;naive CD8 T-cell: 1.6" "Lineage enriched" "Detected in single" 52 "T-cells: 5.1" "Cancer enhanced" "Detected in some" "Sarcoma: 3.2" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 910000 "Cluster 24: Non-specific - Transcription" "Cluster 62: Connective tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "unprognostic (8.69e-2)" "unprognostic (4.73e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.46e-1)" "unprognostic (4.51e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.65e-1)" "unprognostic (1.90e-3)" "unprognostic (1.71e-1)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.02e-5)" "unprognostic (5.91e-3)" "unprognostic (1.62e-1)" "unprognostic (6.11e-2)" "unprognostic (5.02e-2)" PODNL1 "FLJ23447, SLRR5B" ENSG00000132000 "Podocan like 1" Q6PEZ8 19 13931187-13953392 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 11.9;Bipolar cells: 33.6;Leydig cells: 17.6;Paneth cells: 13.3;Peritubular cells: 36.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.8;Rhabdoid: 8.0" "Testis - Peritubular cells, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in some" 11 "spinal cord: 23.2" HPA042807 Approved "Secreted - unknown location" "No annotated function" NA NA "Cluster 21: Testis - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 25: Bipolar cells - Visual perception" "HPA042807: AB_10795514" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (8.08e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.61e-8)" "unprognostic (1.78e-1)" "unprognostic (1.86e-2)" "unprognostic (3.68e-1)" "unprognostic (2.02e-1)" "unprognostic (3.08e-3)" "unprognostic (4.37e-2)" "unprognostic (1.01e-1)" "unprognostic (0.00e+0)" "unprognostic (3.94e-3)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (4.49e-4)" POFUT1 "FUT12, KIAA0180, O-Fuc-T, O-FUT" ENSG00000101346 "Protein O-fucosyltransferase 1" Q9H488 20 32207855-32238658 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism, Notch signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 18.3" "Lineage enriched" "Detected in all" 5 "monocytes: 18.3" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054519, HPA059935" Approved Approved Centrosome "Intracellular and membrane" Enzyme NA NA 60000 "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 22: Proximal enterocytes - Digestion" Centrosome "HPA054519: AB_2682515, HPA059935: AB_2684171" "unprognostic (6.61e-2)" "unprognostic (4.10e-3)" "unprognostic (8.83e-2)" "unprognostic (5.51e-3)" "unprognostic (6.90e-2)" "unprognostic (1.62e-1)" "unprognostic (4.65e-1)" "unprognostic (8.51e-2)" "unprognostic (1.84e-1)" "unprognostic (5.57e-2)" "unprognostic (3.01e-1)" "unprognostic (2.19e-1)" "unprognostic (6.76e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-2)" "unprognostic (5.86e-3)" POFUT2 "C21orf80, FUT13, KIAA0958" ENSG00000186866 "Protein O-fucosyltransferase 2" Q9Y2G5 21 45263928-45287898 "Enzymes, Predicted intracellular proteins" "Carbohydrate metabolism, Fucose metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044297 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" "HPA044297: AB_10965176" "unprognostic (1.32e-2)" "unprognostic (1.65e-3)" "prognostic unfavorable (4.55e-7)" "unprognostic (1.49e-2)" "unprognostic (4.09e-3)" "unprognostic (5.03e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (2.62e-1)" "unprognostic (2.15e-1)" "unprognostic (4.16e-2)" "unprognostic (4.20e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (8.66e-12)" "unprognostic (1.56e-2)" "unprognostic (2.53e-1)" "unprognostic (3.91e-3)" "unprognostic (5.25e-2)" POGLUT1 "9630046K23Rik, C3orf9, hCLP46, KDELCL1, KTELC1, MDS010, MDSRP, MGC32995, Rumi" ENSG00000163389 "Protein O-glucosyltransferase 1" Q8NBL1 3 119468963-119494708 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Gastrulation "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037855, HPA037856" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 14: Langerhans cells - Innate immune response" "Endoplasmic reticulum" "HPA037855: AB_10672728, HPA037856: AB_2732477" "unprognostic (2.43e-1)" "unprognostic (5.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-1)" "unprognostic (2.81e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (6.52e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.02e-7)" "unprognostic (3.08e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-3)" "prognostic favorable (2.23e-4)" POGLUT2 "EP58, KDELC1, MGC5302" ENSG00000134901 "Protein O-glucosyltransferase 2" Q6UW63 13 102784281-102799040 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 25.3;Lymphatic endothelial cells: 13.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Group enriched" "Detected in many" 5 "NK-cells: 3.4;T-cells: 2.2" "Cancer enhanced" "Detected in all" "Kidney cancer: 60.1" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020780, HPA043946, HPA064398" Approved Supported Nucleoplasm "Intracellular and membrane" Enzyme NA NA 44000 "Cluster 1: T-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" Nucleoplasm "CAB020780: , HPA043946: AB_2678743, HPA064398: AB_2685256" "unprognostic (1.97e-2)" "unprognostic (2.34e-1)" "unprognostic (3.21e-1)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (6.68e-3)" "prognostic unfavorable (4.81e-4)" "unprognostic (4.34e-3)" "unprognostic (2.75e-2)" "unprognostic (7.26e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.11e-2)" "unprognostic (1.17e-1)" "unprognostic (2.46e-1)" "unprognostic (2.60e-3)" POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498405 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" POLGARF ORF-Y ENSG00000291307 "POLG alternative reading frame" A0A3B3IS91 15 89330208-89333809 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.1" "Lineage enriched" "Detected in single" 20 "granulocytes: 3.1" "Not detected" "Not detected" "Secreted - unknown location" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 18: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" POLL ENSG00000166169 "DNA polymerase lambda" Q9UGP5 10 101578882-101588270 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076828 Supported Nucleoplasm "Intracellular and membrane" Enzyme NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 46: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 9 Nucleoplasm "HPA076828: " "unprognostic (3.71e-3)" "unprognostic (6.93e-3)" "unprognostic (1.73e-2)" "unprognostic (2.47e-2)" "unprognostic (9.52e-2)" "unprognostic (1.80e-2)" "unprognostic (2.11e-2)" "unprognostic (1.24e-1)" "unprognostic (8.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.12e-2)" "unprognostic (7.19e-2)" "unprognostic (4.74e-2)" "unprognostic (1.06e-2)" "unprognostic (1.94e-1)" "unprognostic (3.86e-1)" "unprognostic (1.64e-3)" POMC "ACTH, CLIP, LPH, MSH, NPP, POC" ENSG00000115138 Proopiomelanocortin P01189 2 25160853-25168903 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Endorphin, Hormone" "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 603 "pituitary gland: 33452.7" "Cell type enhanced" "Detected in many" "Early spermatids: 122.0;Late spermatids: 344.6;Spermatocytes: 74.2" "Cancer enriched" "Detected in many" 6 "testis cancer: 18.5" "Region enriched" "Detected in all" 9 "hypothalamus: 68.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.4;lung cancer: 2.6;lymphoma: 2.8" "Region enriched" "Detected in all" 7 "hypothalamus: 44.0" "Region enriched" "Detected in all" 5 "hypothalamus: 117.7" "CAB002762, HPA046135, HPA063644, CAB079881" Enhanced "Secreted to blood" Hormone NA NA 380000 "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 63: Late spermatids - Spermatogenesis" 13 "CAB002762: , CAB079881: , HPA046135: AB_2679552, HPA063644: AB_2685071" "unprognostic (8.02e-2)" "unprognostic (1.47e-2)" "unprognostic (4.78e-2)" "unprognostic (1.96e-3)" "unprognostic (3.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (4.30e-2)" "unprognostic (8.74e-3)" "unprognostic (1.38e-1)" "prognostic favorable (5.70e-4)" "unprognostic (8.02e-2)" "unprognostic (4.29e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (1.37e-3)" "unprognostic (3.84e-2)" POMGNT2 "AGO61, C3orf39, FLJ14566, GTDC2" ENSG00000144647 "Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)" Q8NAT1 3 43079229-43106085 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034870, HPA040989" Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 79: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 1: Erythroid cells - Oxygen transport" 1 "HPA034870: AB_10602701, HPA040989: AB_2677238" "unprognostic (2.37e-3)" "unprognostic (8.22e-2)" "prognostic favorable (8.13e-5)" "unprognostic (2.57e-2)" "unprognostic (4.17e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.26e-5)" "unprognostic (8.71e-2)" "unprognostic (1.73e-2)" "unprognostic (7.43e-2)" "unprognostic (1.95e-2)" "unprognostic (4.01e-1)" "prognostic favorable (4.00e-7)" "unprognostic (4.98e-2)" "unprognostic (1.55e-1)" "unprognostic (3.26e-1)" "unprognostic (2.57e-1)" PON1 "ESA, PON" ENSG00000005421 "Paraoxonase 1" P27169 7 95297676-95324532 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "liver: 516.3" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 428.5" "Cancer enriched" "Detected in some" 78 "liver cancer: 97.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 1.0;prostate cancer: 2.4" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001610 Approved "Secreted to blood" Enzyme NA NA 96000000000 17000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 43: Hepatocytes - Metabolism" "HPA001610: AB_1079656" "unprognostic (2.02e-2)" "unprognostic (2.41e-2)" "unprognostic (3.04e-1)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "prognostic favorable (7.24e-7)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (9.02e-3)" "unprognostic (1.76e-3)" "unprognostic (3.97e-2)" "unprognostic (6.74e-9)" "unprognostic (1.09e-3)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (5.54e-3)" PON2 ENSG00000105854 "Paraoxonase 2" Q15165 7 95404862-95435329 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 218.5" "Cell type enhanced" "Detected in many" "Astrocytes: 323.9;Extravillous trophoblasts: 353.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 33.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025430, HPA029193" Enhanced "Secreted to blood" Enzyme NA NA 160000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 35: Respiratory epithelial cells - Unknown function" "CAB025430: , HPA029193: AB_10602148" "unprognostic (1.43e-1)" "prognostic unfavorable (1.43e-5)" "unprognostic (3.80e-1)" "unprognostic (4.14e-1)" "unprognostic (3.89e-2)" "unprognostic (3.77e-3)" "unprognostic (1.19e-3)" "unprognostic (9.87e-3)" "unprognostic (9.54e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.80e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (1.40e-1)" "unprognostic (6.43e-2)" "unprognostic (7.99e-3)" "unprognostic (2.56e-1)" PON3 ENSG00000105852 "Paraoxonase 3" Q15166 7 95359872-95396375 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 598.0" "Cell type enriched" "Detected in many" 9 "Hepatocytes: 520.9" "Group enriched" "Detected in many" 9 "liver cancer: 30.8;lung cancer: 7.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 14.6" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA014848, CAB025250" Enhanced "Secreted to blood" Enzyme NA NA 1760000000 380000000 "Cluster 83: Liver - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "CAB025250: , HPA014848: AB_1855540" "unprognostic (2.67e-1)" "unprognostic (1.03e-1)" "unprognostic (6.28e-3)" "unprognostic (5.52e-3)" "unprognostic (1.36e-1)" "unprognostic (4.87e-1)" "unprognostic (1.44e-3)" "unprognostic (6.32e-2)" "unprognostic (1.11e-1)" "unprognostic (6.44e-3)" "unprognostic (9.14e-2)" "unprognostic (7.18e-3)" "unprognostic (8.30e-9)" "unprognostic (1.66e-1)" "unprognostic (1.04e-2)" "unprognostic (8.29e-2)" "unprognostic (5.12e-2)" POSTN "OSF-2, periostin, PN" ENSG00000133110 Periostin Q15063 13 37562583-37598844 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 201.8;stomach 1: 170.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 209.9;Breast myoepithelial cells: 179.0;Endothelial cells: 209.3;Fibroblasts: 246.9;Smooth muscle cells: 119.4" "Cancer enhanced" "Detected in all" "breast cancer: 231.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "breast cancer: 132.1;Rhabdoid: 411.9;testis cancer: 405.9" "Kidney - Podocytes, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 6 "spinal cord: 120.5" "HPA012306, HPA071023" Enhanced Approved "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA 660000000 "Cluster 21: Testis - Unknown function" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 1 "Golgi apparatus" "HPA012306: AB_1854827, HPA071023: " "unprognostic (7.73e-2)" "unprognostic (1.44e-3)" "unprognostic (2.19e-2)" "unprognostic (2.57e-2)" "unprognostic (4.73e-2)" "unprognostic (2.22e-2)" "unprognostic (4.19e-3)" "prognostic unfavorable (2.93e-4)" "unprognostic (3.05e-3)" "unprognostic (7.10e-2)" "unprognostic (1.32e-2)" "unprognostic (5.93e-2)" "prognostic unfavorable (1.83e-7)" "prognostic unfavorable (4.86e-4)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" "unprognostic (8.32e-3)" PPBP "b-TG1, Beta-TG, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, NAP-2-L1, PBP, SCYB7, TGB, TGB1, THBGB1" ENSG00000163736 "Pro-platelet basic protein" P02775 4 73986439-73988190 "Plasma proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 82.3;lymphoid tissue: 52.4" "Cell type enhanced" "Detected in some" "B-cells: 9.1;dendritic cells: 12.6;Kupffer cells: 10.5;Macrophages: 25.2;NK-cells: 39.3;T-cells: 7.3" "Cancer enriched" "Detected in many" 7 "colorectal cancer: 86.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 15 "basophil: 287.2;neutrophil: 86.7" "Lineage enriched" "Detected in all" 23 "granulocytes: 287.2" "Group enriched" "Detected in some" 6 "colorectal cancer: 8.4;lung cancer: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008354, CAB017624" Supported "Secreted to blood" Cytokine NA NA 24500000 2900000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 57: Platelets - Hemostasis" 4 "CAB017624: AB_1127132, HPA008354: AB_1847353" "unprognostic (2.13e-1)" "prognostic unfavorable (6.17e-4)" "unprognostic (7.69e-2)" "unprognostic (1.67e-1)" "unprognostic (4.37e-2)" "unprognostic (3.13e-1)" "unprognostic (2.79e-1)" "unprognostic (6.98e-3)" "unprognostic (2.58e-1)" "unprognostic (4.21e-2)" "unprognostic (1.81e-1)" "unprognostic (2.88e-1)" "unprognostic (2.38e-3)" "unprognostic (1.49e-1)" "unprognostic (2.90e-1)" "unprognostic (2.15e-3)" "unprognostic (2.59e-2)" PPIA CYPA ENSG00000196262 "Peptidylprolyl isomerase A" P62937 7 44796680-44824564 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "CAB004655, HPA058345" Uncertain "Secreted to blood" Enzyme NA NA 230000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 10 "CAB004655: AB_425607, HPA058345: AB_2683685" "unprognostic (3.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.86e-2)" "unprognostic (9.27e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (2.27e-6)" "unprognostic (1.12e-3)" "unprognostic (3.30e-2)" "unprognostic (3.92e-2)" "unprognostic (8.68e-3)" "unprognostic (2.52e-1)" "unprognostic (6.35e-3)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" "unprognostic (7.84e-2)" "unprognostic (1.16e-1)" PPIB "B, CYP-S1, CYPB, OI9, PPIase, SCYLP" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155740-64163134 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Isomerase, Rotamase" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1669.5;Plasma cells: 2246.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" Enzyme No No 33000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 17 "Endoplasmic reticulum" Nucleoplasm "CAB011487: AB_443295, HPA012720: AB_1847399" "unprognostic (3.00e-3)" "unprognostic (5.65e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.65e-1)" "unprognostic (1.07e-3)" "unprognostic (3.69e-2)" "unprognostic (1.27e-2)" "unprognostic (7.19e-2)" "unprognostic (8.80e-3)" "unprognostic (2.87e-1)" "unprognostic (2.79e-2)" "prognostic unfavorable (2.02e-11)" "unprognostic (7.05e-2)" "unprognostic (3.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.90e-2)" PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036725 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 240.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" Enzyme NA NA 3700000 "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 8 "HPA039163: AB_2676374" "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40072710-40097260 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 282.8;Kupffer cells: 235.6;Langerhans cells: 343.4;Macrophages: 231.7;Schwann cells: 213.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 1254.9;eosinophil: 625.5;intermediate monocyte: 1006.3;myeloid DC: 1091.1;neutrophil: 685.3;non-classical monocyte: 818.8" "Group enriched" "Detected in all" 4 "dendritic cells: 1091.1;granulocytes: 685.3;monocytes: 1254.9" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 240000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" 4 "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" PPT2 ENSG00000221988 "Palmitoyl-protein thioesterase 2" Q9UMR5 6 32153441-32163678 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.4;Syncytiotrophoblasts: 21.9" "Cancer enhanced" "Detected in all" "melanoma: 21.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000559 Uncertain "Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 66: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" "Golgi apparatus" "Vesicles, Cytosol" "HPA000559: " "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.03e-5)" "unprognostic (1.62e-1)" "unprognostic (6.75e-3)" "unprognostic (2.92e-3)" "unprognostic (6.41e-3)" "unprognostic (7.12e-2)" "unprognostic (2.56e-3)" "unprognostic (5.28e-3)" "unprognostic (1.12e-2)" "unprognostic (2.75e-3)" "unprognostic (5.09e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.24e-3)" PPY PNP ENSG00000108849 "Pancreatic polypeptide" P01298 17 43940804-43942476 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "pancreas: 169.2" "Cell type enriched" "Detected in some" 22 "Pancreatic endocrine cells: 533.2" "Cancer enriched" "Detected in some" 132 "pancreatic cancer: 630.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 1.2" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.2" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB016735, HPA032122" Enhanced "Secreted to blood" Hormone NA NA 70300 44000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 "CAB016735: , HPA032122: AB_2674164" "unprognostic (5.12e-3)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.65e-2)" "unprognostic (7.56e-3)" "unprognostic (8.13e-2)" "unprognostic (1.33e-1)" "unprognostic (7.78e-3)" "unprognostic (1.42e-1)" PRAC2 "C17orf93, HOXB-AS5, HOXB13-AS1, NCRNA00253" ENSG00000229637 "PRAC2 small nuclear protein" D3DTV9 17 48723185-48724758 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "intestine: 9.3;prostate: 12.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 20.3;Early spermatids: 20.4;Enteroendocrine cells: 23.7;Intestinal goblet cells: 13.1;Late spermatids: 61.1;Paneth cells: 15.1;Prostatic glandular cells: 44.1;Undifferentiated cells: 28.4" "Cancer enriched" "Detected in many" 8 "prostate cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 16.3;prostate cancer: 44.6" "Prostate - Prostate glandular cells, Testis - Late spermatids" "Intracellular and membrane" "No annotated function" NA NA "Cluster 45: Intestine - Digestion" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "unprognostic (1.22e-2)" "unprognostic (1.45e-1)" "unprognostic (4.26e-2)" "unprognostic (2.04e-1)" "unprognostic (1.63e-2)" "unprognostic (9.98e-2)" "unprognostic (3.27e-2)" "unprognostic (9.77e-2)" "unprognostic (8.97e-2)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" PRADC1 "C2orf7, hPAP21, MGC13004, PAP21" ENSG00000135617 "Protease associated domain containing 1" Q9BSG0 2 73228010-73233239 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 122.2" "Cell type enhanced" "Detected in all" "Late spermatids: 140.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051066 Approved "Secreted to blood" "No annotated function" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 7: Liver cancer - Metabolism" "Cluster 39: Non-specific - Basic cellular processes" 1 "HPA051066: AB_2681333" "unprognostic (2.94e-1)" "unprognostic (1.93e-2)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" "unprognostic (9.23e-2)" "unprognostic (3.93e-2)" "unprognostic (8.54e-2)" "unprognostic (9.08e-3)" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (1.09e-3)" "unprognostic (9.99e-3)" "unprognostic (3.56e-2)" "unprognostic (2.96e-1)" "unprognostic (4.89e-1)" "unprognostic (1.93e-1)" "unprognostic (9.23e-2)" PRAP1 UPA ENSG00000165828 "Proline rich acidic protein 1" Q96NZ9 10 133347368-133352683 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 1103.8;liver: 653.6" "Cell type enriched" "Detected in some" 16 "Proximal enterocytes: 12236.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 348.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 95.2;Gastric cancer: 40.0;liver cancer: 30.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA038713, HPA052451" Supported "Secreted to digestive system" "No annotated function" NA NA 210000000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 7 "HPA038713: AB_10673117, HPA052451: AB_2681839" "unprognostic (1.63e-3)" "unprognostic (1.79e-2)" "unprognostic (1.09e-1)" "unprognostic (1.89e-3)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (8.90e-2)" "unprognostic (3.60e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (4.35e-3)" "unprognostic (4.91e-2)" "unprognostic (8.23e-3)" "unprognostic (2.25e-1)" "unprognostic (3.15e-1)" "unprognostic (2.92e-2)" "unprognostic (2.22e-3)" PRB1 "PM, PMF, PMS, PRB1L, PRB1M" ENSG00000251655 "Proline rich protein BstNI subfamily 1" 12 11351823-11355591 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 992 "salivary gland: 6182.2" "Cell type enriched" "Detected in some" 44 "Serous glandular cells: 9574.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 66: Non-specific - Mitochondria" "Cluster 75: Serous glandular cells - Salivary secretion" PRB2 "cP7, PRPPRB1, Ps" ENSG00000121335 "Proline rich protein BstNI subfamily 2" P02812 12 11391540-11501041 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 3818 "salivary gland: 11778.1" "Cell type enriched" "Detected in some" 45 "Serous glandular cells: 6235.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" "No annotated function" NA NA 25000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" "unprognostic (1.36e-1)" "unprognostic (1.01e-2)" "unprognostic (2.61e-1)" "unprognostic (2.07e-2)" "unprognostic (9.21e-2)" "unprognostic (5.51e-3)" "unprognostic (1.97e-4)" "unprognostic (1.51e-1)" PRB3 PRG ENSG00000197870 "Proline rich protein BstNI subfamily 3" Q04118 12 11265914-11269707 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1882 "salivary gland: 13472.2" "Cell type enriched" "Detected in some" 45 "Serous glandular cells: 98229.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0;lung cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" "No annotated function" NA NA 27000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 75: Serous glandular cells - Salivary secretion" 5 "unprognostic (4.12e-2)" "unprognostic (1.34e-1)" "unprognostic (1.05e-3)" "unprognostic (1.51e-1)" "unprognostic (7.46e-3)" "unprognostic (4.12e-2)" "unprognostic (9.65e-2)" "unprognostic (1.94e-2)" "unprognostic (8.27e-2)" "unprognostic (9.98e-2)" "unprognostic (2.35e-1)" "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" PRB4 ENSG00000230657 "Proline rich protein BstNI subfamily 4" 12 11307077-11310436 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 207 "salivary gland: 3551.4" "Cell type enriched" "Detected in some" 42 "Serous glandular cells: 38773.3" "Group enriched" "Detected in some" 10 "lung cancer: 2.0;melanoma: 0.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 75: Serous glandular cells - Salivary secretion" "unprognostic (1.05e-1)" "unprognostic (8.25e-2)" PRCD RP36 ENSG00000214140 "Photoreceptor disc component" Q00LT1 17 76527586-76553578 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "retina: 46.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 165.9;Cone photoreceptor cells: 424.8;Muller glia cells: 89.5;Rod photoreceptor cells: 478.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 3.3" "Low region specificity" "Detected in many" "Intracellular and membrane" Other NA NA "Cluster 76: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" "unprognostic (3.50e-2)" "unprognostic (1.83e-3)" "unprognostic (3.74e-1)" "unprognostic (1.31e-4)" "unprognostic (6.56e-2)" "unprognostic (4.07e-3)" "unprognostic (1.76e-1)" "unprognostic (2.07e-1)" "unprognostic (4.04e-2)" "unprognostic (2.45e-1)" "unprognostic (1.19e-6)" "unprognostic (1.03e-1)" "unprognostic (1.10e-1)" "unprognostic (8.94e-3)" "unprognostic (1.39e-2)" PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82822936-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" Enzyme NA NA 42000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 53: Non-specific - Glycosylation" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Vesicles "HPA017065: AB_1855676, HPA071115: " "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.33e-2)" "unprognostic (9.22e-2)" "unprognostic (1.42e-1)" "unprognostic (7.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.88e-2)" "prognostic favorable (2.65e-6)" "unprognostic (7.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" PRDM12 PFM9 ENSG00000130711 "PR/SET domain 12" Q9H4Q4 9 130664594-130682986 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Excitatory neurons: 1.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 5.5;hypothalamus: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "Sarcoma: 10.8" "Region enriched" "Detected in some" 7 "basal ganglia: 10.9" "Group enriched" "Detected in some" 24 "basal ganglia: 4.7;hypothalamus: 1.6" HPA043143 Uncertain Approved Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 65: Neurons - Synaptic function" Nucleoplasm "HPA043143: AB_10806379" "unprognostic (3.25e-2)" "unprognostic (2.32e-1)" "unprognostic (3.40e-1)" "unprognostic (1.81e-4)" "unprognostic (7.90e-2)" "unprognostic (4.75e-3)" "unprognostic (2.48e-3)" "unprognostic (4.18e-2)" "unprognostic (4.61e-1)" "unprognostic (2.70e-1)" "unprognostic (6.43e-2)" "unprognostic (7.58e-2)" "unprognostic (4.03e-3)" "unprognostic (3.01e-2)" "unprognostic (4.79e-2)" "unprognostic (6.30e-4)" "unprognostic (1.40e-1)" PRDX4 AOE37-2 ENSG00000123131 "Peroxiredoxin 4" Q13162 X 23664262-23686397 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 1173.7" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 597.0;Late spermatids: 1035.4;Plasma cells: 936.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008659, CAB027389, CAB047362, HPA067039, CAB080373, CAB080374" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Enzyme NA NA 4400000 "Cluster 14: Non-specific - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 5 "Endoplasmic reticulum" Cytosol "CAB008659: AB_1620984, CAB027389: , CAB047362: , CAB080373: , CAB080374: , HPA067039: " "unprognostic (3.82e-2)" "unprognostic (6.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.06e-3)" "unprognostic (1.64e-1)" "unprognostic (1.65e-2)" "unprognostic (1.29e-3)" "unprognostic (1.08e-1)" "unprognostic (8.32e-2)" "unprognostic (3.75e-2)" "unprognostic (2.97e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (7.44e-2)" "unprognostic (1.29e-1)" "unprognostic (3.56e-1)" "unprognostic (4.10e-2)" PRELP "prolargin, SLRR2A" ENSG00000188783 "Proline and arginine rich end leucine rich repeat protein" P51888 1 203475806-203491352 "Plasma proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Fibroblasts: 255.8;Leydig cells: 96.5;Melanocytes: 319.5;Muller glia cells: 147.6;Ovarian stromal cells: 159.8;Peritubular cells: 199.1;Smooth muscle cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.1" "Cancer enhanced" "Detected in some" "Brain cancer: 3.8;testis cancer: 4.8" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 112.6" HPA059225 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" Other NA NA 450000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "Endoplasmic reticulum" "HPA059225: " "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.83e-2)" "unprognostic (6.56e-2)" "unprognostic (2.75e-2)" "unprognostic (1.61e-1)" "unprognostic (2.84e-2)" "unprognostic (3.98e-2)" "unprognostic (2.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (5.62e-6)" "unprognostic (2.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.02e-4)" PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.1;lung: 16.0;lymphoid tissue: 48.3" "Cell type enriched" "Detected in some" 4 "NK-cells: 1101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 900.8;MAIT T-cell: 628.8;memory CD8 T-cell: 498.2;naive CD8 T-cell: 313.2;NK-cell: 657.0" "Group enriched" "Detected in all" 50 "NK-cells: 657.0;T-cells: 900.8" "Cancer enriched" "Detected in some" 7 "lymphoma: 61.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Lung - NK-cells (Lung), Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" Other NA NA 2100000 "Cluster 15: NK-cells - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" 3 Cytosol "CAB002436: AB_563955, HPA037940: AB_2675747" "unprognostic (6.11e-3)" "unprognostic (1.26e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.09e-4)" "unprognostic (1.87e-2)" "prognostic favorable (3.54e-4)" "unprognostic (6.98e-3)" "unprognostic (2.62e-1)" "unprognostic (1.44e-3)" "unprognostic (1.69e-2)" "unprognostic (5.22e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.08e-5)" "unprognostic (7.38e-2)" "unprognostic (2.70e-1)" "unprognostic (7.97e-3)" "unprognostic (5.22e-3)" PRG2 "BMPG, MBP, proMBP" ENSG00000186652 "Proteoglycan 2, pro eosinophil major basic protein" P13727 11 57386780-57390650 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Immunity "Antibiotic, Antimicrobial, Heparin-binding" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "placenta: 2526.3" "Group enriched" "Detected in some" 21 "Erythroid cells: 34.9;Extravillous trophoblasts: 106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 36 "basophil: 7.3" "Lineage enriched" "Detected in single" 74 "granulocytes: 7.3" "Cancer enriched" "Detected in some" 47 "Leukemia: 370.8" "Lung - Neutrophil_1" "Not detected" "Not detected" "Not detected" "Not detected" HPA038515 Supported "Secreted in female reproductive system" Immunity NA NA 100000000 "Cluster 58: Placenta - Pregnancy" "Cluster 49: HMC-1 - Innate immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "HPA038515: AB_10675800" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (3.39e-2)" "unprognostic (3.49e-1)" "unprognostic (8.62e-4)" "unprognostic (4.77e-3)" "unprognostic (3.20e-2)" "unprognostic (4.17e-2)" "unprognostic (2.26e-2)" "unprognostic (5.19e-3)" "unprognostic (2.17e-1)" "unprognostic (1.40e-11)" "unprognostic (4.26e-2)" "unprognostic (4.52e-3)" "unprognostic (6.47e-2)" "unprognostic (2.32e-1)" PRG3 "MBP2, MBPH" ENSG00000156575 "Proteoglycan 3, pro eosinophil major basic protein 2" Q9Y2Y8 11 57376769-57381150 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "bone marrow: 47.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 27 "Leukemia: 2.7" "Lung - Neutrophil_1" "Not detected" "Not detected" "Not detected" "Not detected" HPA064183 Enhanced "Secreted in other tissues" "No annotated function" NA NA 680000 "Cluster 6: Bone marrow - Innate immune response" "Cluster 49: HMC-1 - Innate immune response" "HPA064183: AB_2685205" PRG4 "bG174L6.2, CACP, FLJ32635, HAPO, JCAP, MSF, SZP" ENSG00000116690 "Proteoglycan 4" Q92954 1 186296279-186314567 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 90.2;liver: 180.2" "Cell type enriched" "Detected in some" 11 "Mesothelial cells: 3614.7" "Cancer enriched" "Detected in many" 10 "liver cancer: 28.4" "Region enriched" "Detected in some" 8 "hypothalamus: 66.4" "Immune cell enriched" "Detected in single" 5 "T-reg: 1.2" "Lineage enriched" "Detected in single" 12 "T-cells: 1.2" "Cancer enriched" "Detected in some" 18 "Rhabdoid: 33.0" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" CAB054258 Supported "Secreted to extracellular matrix" "No annotated function" NA NA 4300000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "CAB054258: " "unprognostic (8.67e-2)" "unprognostic (2.28e-1)" "unprognostic (1.82e-3)" "unprognostic (1.98e-1)" "unprognostic (1.77e-1)" "unprognostic (7.87e-2)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (1.28e-1)" "unprognostic (1.53e-1)" "unprognostic (5.03e-2)" "unprognostic (4.11e-1)" "unprognostic (1.91e-13)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (1.60e-3)" "unprognostic (7.05e-3)" PRH2 Pr ENSG00000134551 "Proline rich protein HaeIII subfamily 2" P02810 12 10929236-10934845 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 909 "salivary gland: 22313.4" "Cell type enriched" "Detected in some" 40 "Serous glandular cells: 24492.9" "Cancer enriched" "Detected in some" 11 "head and neck cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted to digestive system" "No annotated function" NA NA 21000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (3.65e-2)" "unprognostic (3.59e-1)" "unprognostic (1.25e-1)" "unprognostic (5.52e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.01e-2)" "unprognostic (7.37e-2)" "unprognostic (1.63e-5)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (4.26e-1)" "unprognostic (3.43e-2)" PRKCSH "G19P1, GIIB, PCLD, PLD1, VASAP-60" ENSG00000130175 "Protein kinase C substrate 80K-H" P14314 19 11435284-11450968 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004465, HPA041940, HPA043560" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 55000000 "Cluster 29: Non-specific - Unknown function" "Cluster 18: Non-specific - Ribosome" "Cluster 30: White matter - Myelination" "Cluster 23: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" 1 "Endoplasmic reticulum" "CAB004465: AB_626622, HPA041940: AB_2677758, HPA043560: AB_2678553" "unprognostic (2.75e-1)" "unprognostic (1.67e-1)" "unprognostic (2.45e-2)" "unprognostic (2.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.63e-2)" "unprognostic (2.52e-2)" "unprognostic (5.52e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-3)" "unprognostic (1.28e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (7.69e-4)" "unprognostic (1.63e-3)" "unprognostic (2.10e-1)" "unprognostic (3.44e-1)" "unprognostic (1.18e-1)" PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 343.4;Excitatory neurons: 142.7;Inhibitory neurons: 164.5;Microglial cells: 85.0;Oligodendrocyte precursor cells: 366.5" "Cancer enhanced" "Detected in all" "prostate cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 16.0" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Immunity NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 39: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 6 "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.89e-1)" PRL ENSG00000172179 Prolactin P01236 6 22287244-22302826 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Lactation Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1033 "pituitary gland: 36497.9" "Group enriched" "Detected in some" 5 "Early spermatids: 13.5;Late spermatids: 29.0;Oocytes: 19.9;Rod photoreceptor cells: 15.9;Skeletal myocytes: 33.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Leukemia: 10.8;lymphoma: 9.9;ovarian cancer: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB023353, HPA042416, HPA062017" Enhanced "Secreted to blood" Hormone NA NA 53900000 7200000 "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "CAB023353: AB_617369, HPA042416: AB_2677987, HPA062017: AB_2684660" "unprognostic (1.66e-1)" "unprognostic (4.08e-3)" "unprognostic (5.89e-3)" "unprognostic (4.83e-3)" "unprognostic (2.87e-1)" "unprognostic (1.11e-4)" "unprognostic (4.54e-1)" "unprognostic (1.57e-1)" "unprognostic (3.79e-2)" "unprognostic (4.29e-5)" "unprognostic (2.20e-1)" PRLH PRH ENSG00000071677 "Prolactin releasing hormone" P81277 2 237566574-237567175 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.6;heart muscle: 1.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.7" "Region enhanced" "Detected in many" "medulla oblongata: 47.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.0" "Group enriched" "Detected in some" 58 "hypothalamus: 11.3;pons and medulla: 21.5" "Region enriched" "Detected in single" 14 "medulla oblongata: 1.5" HPA014976 Uncertain "Secreted in brain" Hormone NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "HPA014976: AB_2732413" "unprognostic (8.28e-4)" "unprognostic (3.22e-2)" "unprognostic (5.42e-2)" PRLR ENSG00000113494 "Prolactin receptor" P16471 5 35048756-35230487 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 124.2;parathyroid gland: 79.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 59.1;Breast glandular cells: 71.4;Endometrial stromal cells: 107.2;Proximal tubular cells: 46.7;Syncytiotrophoblasts: 65.0" "Cancer enriched" "Detected in many" 9 "breast cancer: 20.6" "Region enriched" "Detected in all" 19 "choroid plexus: 1734.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "breast cancer: 36.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 2 "unprognostic (3.81e-2)" "unprognostic (2.41e-1)" "unprognostic (2.37e-2)" "unprognostic (6.04e-2)" "unprognostic (5.05e-2)" "unprognostic (8.21e-2)" "unprognostic (3.99e-2)" "unprognostic (7.94e-2)" "unprognostic (4.89e-2)" "unprognostic (1.67e-3)" "unprognostic (4.84e-4)" "unprognostic (2.50e-3)" "unprognostic (4.15e-3)" "unprognostic (1.89e-1)" "unprognostic (1.12e-1)" "unprognostic (9.84e-5)" "unprognostic (1.24e-1)" PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "liver: 584.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 339.4" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.8" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.8" "Cancer enriched" "Detected in many" 6 "liver cancer: 28.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Outer root sheath cells" "Not detected" "Not detected" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" "Blood coagulation" NA NA 5200000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 31: Liver - Plasma proteins" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" PROK1 "EGVEGF, PK1, PRK1" ENSG00000143125 "Prokineticin 1" P58294 1 110451149-110457358 "Predicted secreted proteins" Angiogenesis "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "ovary: 190.9;placenta: 48.5;testis: 57.3" "Cell type enhanced" "Detected in some" "Granulosa cells: 220.9;Leydig cells: 159.3;Ovarian stromal cells: 80.7;Peritubular cells: 649.2" "Cancer enhanced" "Detected in many" "testis cancer: 4.7" "Region enhanced" "Detected in many" "medulla oblongata: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.3;Rhabdoid: 1.2" "Stomach - Macrophages" "Region enriched" "Detected in single" 11 "pons and medulla: 1.4" "Low region specificity" "Detected in many" "Secreted to blood" "Growth factor" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 6: Ovarian stromal cells - Transcription" "unprognostic (2.66e-1)" "unprognostic (2.71e-2)" "unprognostic (1.30e-1)" "unprognostic (1.42e-1)" "unprognostic (1.37e-3)" "unprognostic (2.26e-1)" "unprognostic (1.86e-1)" "unprognostic (3.86e-1)" "unprognostic (6.80e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-2)" "unprognostic (7.39e-3)" "unprognostic (1.90e-1)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" PROK2 "BV8, KAL4, MIT1, PK2" ENSG00000163421 "Prokineticin 2" Q9HC23 3 71771655-71785206 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biological rhythms" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.7;lymphoid tissue: 21.9" "Cell type enhanced" "Detected in some" "Macrophages: 12.2;Oocytes: 31.6;Serous glandular cells: 12.1;Spermatocytes: 18.2" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.1" "Region enriched" "Detected in many" 7 "cerebral cortex: 30.8" "Immune cell enriched" "Detected in many" 50 "neutrophil: 416.1" "Lineage enriched" "Detected in many" 50 "granulocytes: 416.1" "Cancer enhanced" "Detected in some" "Leukemia: 8.0;Myeloma: 5.7" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Testis - Early spermatids, Thyroid - Neutrophils" "Group enriched" "Detected in some" 6 "basal ganglia: 2.7;hypothalamus: 1.1;olfactory bulb: 3.5" "Low region specificity" "Detected in many" HPA041408 Approved "Secreted to blood" Neuropeptide NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 1 "HPA041408: AB_10964057" "unprognostic (5.24e-2)" "unprognostic (3.13e-3)" "unprognostic (3.51e-3)" "unprognostic (3.59e-2)" "unprognostic (1.89e-1)" "unprognostic (2.94e-1)" "unprognostic (2.97e-2)" "unprognostic (9.52e-2)" "unprognostic (4.29e-2)" "unprognostic (9.91e-3)" "unprognostic (6.89e-2)" "unprognostic (5.73e-1)" "unprognostic (1.59e-4)" "unprognostic (2.02e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" PROS1 PROS ENSG00000184500 "Protein S" P07225 3 93873051-93980003 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 137.3;liver: 274.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 261.3;Mesothelial cells: 85.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 64.8" "Region enriched" "Detected in all" 34 "choroid plexus: 214.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 46.7" "Breast - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007724, HPA023974, CAB032610" Approved "Secreted to blood" "Blood coagulation" NA NA 22500000000 5000000000 "Cluster 83: Liver - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 4 "CAB032610: AB_2237647, HPA007724: AB_1079688, HPA023974: AB_1855738" "unprognostic (2.00e-2)" "unprognostic (2.81e-2)" "unprognostic (9.21e-2)" "unprognostic (8.03e-3)" "unprognostic (3.35e-2)" "unprognostic (2.41e-1)" "unprognostic (6.48e-2)" "unprognostic (3.07e-1)" "unprognostic (5.18e-2)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.35e-4)" "unprognostic (4.90e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.42e-5)" PROZ PZ ENSG00000126231 "Protein Z, vitamin K dependent plasma glycoprotein" P22891 13 113158648-113172386 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 106.6" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 63.9" "Cancer enriched" "Detected in single" 27 "liver cancer: 12.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" HPA052006 Supported "Secreted to blood" "Blood coagulation" NA NA 1720000000 650000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 5: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 62: Hepatocytes - Metabolism" 1 "HPA052006: AB_2681691" "unprognostic (5.03e-2)" "unprognostic (4.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.36e-1)" "unprognostic (6.48e-2)" "unprognostic (1.39e-1)" "prognostic favorable (3.46e-4)" "unprognostic (4.10e-1)" "unprognostic (2.21e-1)" "unprognostic (2.50e-1)" "unprognostic (5.20e-2)" "unprognostic (2.87e-1)" "unprognostic (9.83e-2)" "unprognostic (5.63e-2)" "unprognostic (1.41e-1)" "unprognostic (9.99e-2)" "unprognostic (2.51e-4)" PRR27 C4orf40 ENSG00000187533 "Proline rich 27" Q6MZM9 4 70133616-70176799 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 959 "salivary gland: 1071.7" "Cell type enriched" "Detected in some" 31 "Serous glandular cells: 1008.1" "Cancer enriched" "Detected in single" 10 "breast cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "HPA036150, HPA036151" Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 34: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA036150: AB_10673001, HPA036151: AB_2674971" "unprognostic (9.52e-2)" PRR4 "LPRP, PROL4" ENSG00000111215 "Proline rich 4" Q16378 12 10845849-10849475 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 45 "salivary gland: 6424.4" "Cell type enriched" "Detected in some" 14 "Serous glandular cells: 1903.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "skin cancer: 5.0" "Skin - Eccrine sweat gland cells" HPA042133 Supported "Secreted to digestive system" "No annotated function" NA NA 14000000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 69: Skin cancer - ECM organization" "Cluster 75: Serous glandular cells - Salivary secretion" 5 "HPA042133: AB_10793979" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.35e-2)" "unprognostic (1.74e-2)" "unprognostic (1.99e-1)" "unprognostic (5.03e-2)" "unprognostic (3.01e-3)" "unprognostic (3.91e-2)" "unprognostic (1.70e-1)" "unprognostic (1.23e-1)" "unprognostic (3.19e-2)" "unprognostic (1.09e-2)" "unprognostic (3.57e-6)" "unprognostic (2.81e-2)" "unprognostic (9.15e-2)" "unprognostic (1.21e-1)" "unprognostic (2.15e-2)" PRRT3 FLJ33674 ENSG00000163704 "Proline rich transmembrane protein 3" Q5FWE3 3 9939450-9952408 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 14.4;choroid plexus: 7.2;fallopian tube: 7.3;parathyroid gland: 14.7;pituitary gland: 10.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 22.7;Rod photoreceptor cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035127, HPA035128, HPA069859" Enhanced Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA 83000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 37: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 55: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA035127: AB_10602822, HPA035128: AB_2674482, HPA069859: " "unprognostic (1.55e-1)" "unprognostic (8.41e-2)" "unprognostic (3.42e-1)" "unprognostic (2.38e-3)" "unprognostic (1.27e-1)" "unprognostic (3.41e-2)" "unprognostic (1.15e-4)" "unprognostic (2.27e-3)" "unprognostic (1.37e-2)" "unprognostic (2.76e-2)" "unprognostic (2.20e-3)" "unprognostic (3.60e-1)" "unprognostic (1.01e-4)" "unprognostic (2.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.64e-2)" "unprognostic (2.09e-1)" PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361690 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 15.7;bone marrow: 57.0" "Group enriched" "Detected in some" 10 "Horizontal cells: 19.5;Inhibitory neurons: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 27.0;Neuroblastoma: 70.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Neutrophil_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: AB_2679642, HPA052681: AB_2681912" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.36e-3)" "unprognostic (1.20e-4)" "unprognostic (2.60e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-4)" "unprognostic (9.11e-2)" "unprognostic (3.73e-4)" "unprognostic (5.28e-3)" "unprognostic (9.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753072 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4460 "pancreas: 328383.5" "Cell type enriched" "Detected in some" 71 "Exocrine glandular cells: 25170.5" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 25.9" "Pancreas - Exocrine glandular cells" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" Enzyme NA NA 100000000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Pancreatic exocrine cells - Proteolysis" Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavorable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.12e-1)" PRSS12 "BSSP-3, MRT1" ENSG00000164099 "Serine protease 12" P56730 4 118280038-118353003 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 45.4;Cytotrophoblasts: 48.6;Distal enterocytes: 23.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "choroid plexus: 32.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 86.9" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035054 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" "HPA035054: AB_10603990" "unprognostic (4.30e-2)" "unprognostic (1.04e-2)" "unprognostic (2.55e-1)" "unprognostic (4.41e-2)" "prognostic favorable (2.66e-4)" "prognostic favorable (1.03e-4)" "unprognostic (4.21e-1)" "unprognostic (3.48e-2)" "unprognostic (7.83e-2)" "unprognostic (6.38e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.29e-1)" "unprognostic (1.85e-1)" "unprognostic (9.55e-2)" "unprognostic (1.09e-1)" PRSS16 TSSP ENSG00000112812 "Serine protease 16" Q9NQE7 6 27247701-27256624 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 59 "lymphoid tissue: 804.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 42.6;Extravillous trophoblasts: 26.7;Syncytiotrophoblasts: 32.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.1" "Lineage enhanced" "Detected in single" "B-cells: 2.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 71: Thymus - Adaptive immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" "unprognostic (1.50e-1)" "unprognostic (6.95e-2)" "unprognostic (1.91e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (1.74e-2)" "unprognostic (9.21e-3)" "unprognostic (1.57e-1)" "unprognostic (7.89e-2)" "prognostic favorable (6.46e-5)" "unprognostic (1.57e-1)" "unprognostic (3.49e-2)" "unprognostic (5.42e-2)" "unprognostic (1.95e-1)" "unprognostic (5.49e-2)" "unprognostic (2.10e-1)" "unprognostic (1.62e-2)" PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 452 "pancreas: 232476.3" "Cell type enriched" "Detected in some" 22 "Exocrine glandular cells: 56266.6" "Cancer enriched" "Detected in many" 72 "pancreatic cancer: 3463.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basophil: 4.1;T-reg: 2.9" "Group enriched" "Detected in many" 8 "granulocytes: 4.1;T-cells: 2.9" "Cancer enhanced" "Detected in many" "Myeloma: 203.2;pancreatic cancer: 63.8" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" Enzyme NA NA 890000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Pancreatic exocrine cells - Proteolysis" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "prognostic favorable (2.32e-4)" "unprognostic (3.80e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-3)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (3.50e-1)" "unprognostic (5.36e-3)" "unprognostic (1.18e-1)" PRSS21 "ESP-1, TEST1" ENSG00000007038 "Serine protease 21" Q9Y6M0 16 2817180-2826304 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 82.3" "Cell type enhanced" "Detected in many" "Early spermatids: 104.5;Late spermatids: 342.5;Spermatocytes: 484.7;Spermatogonia: 202.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 23.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "basophil: 16.2;eosinophil: 33.0" "Lineage enriched" "Detected in all" 7 "granulocytes: 33.0" "Cancer enhanced" "Detected in many" "cervical cancer: 23.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008477 Enhanced Approved Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 46: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 1 Cytosol "HPA008477: AB_1079697" "unprognostic (4.35e-2)" "unprognostic (3.46e-2)" "unprognostic (7.06e-2)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (7.02e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (2.33e-1)" "unprognostic (5.21e-2)" "unprognostic (8.83e-3)" "unprognostic (1.52e-3)" "unprognostic (2.97e-2)" "unprognostic (1.14e-2)" "unprognostic (5.07e-2)" "unprognostic (7.79e-2)" "unprognostic (2.99e-1)" PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 77.4;salivary gland: 26.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 149.0;Club cells: 240.4;Ductal cells: 104.1;Ionocytes: 445.1;Secretory cells: 110.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 24.6" "Colon - Colon enterocytes, Kidney - Endothelial cells, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" Enzyme NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "HPA049161: AB_2680660" "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" PRSS23 "SIG13, SPUVE" ENSG00000150687 "Serine protease 23" O95084 11 86791059-86952910 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 239.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 347.2;Club cells: 326.4;Endothelial cells: 346.0;Granulosa cells: 346.2;Ionocytes: 361.9;Lymphatic endothelial cells: 440.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 104.9" "Group enriched" "Detected in many" 25 "NK-cells: 34.2;T-cells: 104.9" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030591 Uncertain "Secreted to blood" Enzyme NA NA 440000 "Cluster 15: NK-cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "HPA030591: AB_10602067" "unprognostic (2.68e-2)" "unprognostic (1.20e-2)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (2.40e-3)" "prognostic unfavorable (2.12e-4)" "unprognostic (1.89e-2)" "unprognostic (4.30e-2)" "unprognostic (2.08e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (5.56e-4)" "unprognostic (5.35e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.13e-3)" "unprognostic (9.44e-2)" "unprognostic (1.99e-3)" "unprognostic (8.01e-2)" PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.2;esophagus: 377.7;vagina: 130.1" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 78.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" Enzyme NA NA 8700000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750679-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 267 "pancreas: 30122.2" "Group enriched" "Detected in many" 4 "Distal enterocytes: 1079.5;Exocrine glandular cells: 1140.0;Paneth cells: 531.4;Proximal enterocytes: 1105.5" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 104 "basophil: 159.5" "Lineage enriched" "Detected in many" 104 "granulocytes: 159.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 117.9" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Late spermatids" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" Enzyme NA NA 700000000 "Cluster 46: Basophils - Proteolysis" "Cluster 15: Pancreas - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 60: Pancreatic exocrine cells - Proteolysis" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" PRSS33 EOS ENSG00000103355 "Serine protease 33" Q8NF86 16 2783953-2787948 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "fallopian tube: 4.7" "Cell type enriched" "Detected in some" 6 "Secretory cells: 13.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 8.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 68 "eosinophil: 1353.2" "Lineage enriched" "Detected in many" 390 "granulocytes: 1353.2" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.2;skin cancer: 4.9" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 4.0" "Secreted to blood" Enzyme NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 59: Fallopian tube - Tissue development" "Cluster 69: Skin cancer - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" "unprognostic (4.78e-1)" "unprognostic (1.22e-1)" "unprognostic (8.99e-2)" "unprognostic (3.38e-2)" "unprognostic (3.10e-1)" "unprognostic (2.86e-2)" "unprognostic (1.16e-1)" "unprognostic (4.13e-2)" "unprognostic (1.16e-1)" "unprognostic (1.42e-2)" "unprognostic (2.28e-1)" "unprognostic (1.91e-1)" "unprognostic (2.70e-2)" PRSS35 "C6orf158, dJ223E3.1, MGC46520" ENSG00000146250 "Serine protease 35" Q8N3Z0 6 83512534-83525704 "Enzymes, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 18.4;retina: 49.0" "Cell type enriched" "Detected in some" 25 "Muller glia cells: 330.8" "Group enriched" "Detected in some" 4 "glioma: 2.8;testis cancer: 4.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in single" 196 "T-cells: 19.5" "Group enriched" "Detected in many" 4 "Bone cancer: 34.4;Brain cancer: 15.4;testis cancer: 16.5" "Kidney - Ascending Loop of Henle cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 3.8;cerebellum: 4.9;cerebral cortex: 7.7;hippocampal formation: 7.0;olfactory bulb: 3.6" "HPA038787, HPA038788" Uncertain "Secreted in female reproductive system" Other NA NA "Cluster 1: T-cells - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 10: Muller glia cells - Visual perception" 1 "HPA038787: AB_10675951, HPA038788: AB_2676208" "unprognostic (6.17e-2)" "unprognostic (8.75e-2)" "unprognostic (1.19e-2)" "unprognostic (2.63e-2)" "unprognostic (1.16e-1)" "unprognostic (4.03e-2)" "unprognostic (3.70e-4)" "unprognostic (6.08e-2)" "unprognostic (1.18e-3)" "unprognostic (2.33e-2)" "unprognostic (7.01e-2)" "unprognostic (9.07e-2)" "unprognostic (3.88e-6)" "unprognostic (7.15e-3)" "unprognostic (5.81e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-4)" PRSS36 FLJ90661 ENSG00000178226 "Serine protease 36" Q5K4E3 16 31138926-31150083 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 2.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.0;Hofbauer cells: 16.8;Proximal enterocytes: 48.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA036079 Uncertain "Secreted to extracellular matrix" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 45: Intestine - Digestion" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" "HPA036079: AB_10602290" "unprognostic (3.74e-2)" "prognostic favorable (2.97e-7)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (4.26e-3)" "unprognostic (1.31e-5)" "unprognostic (4.18e-2)" "unprognostic (5.05e-2)" "unprognostic (2.65e-2)" "unprognostic (8.03e-2)" "unprognostic (2.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (9.86e-2)" "unprognostic (1.23e-1)" "unprognostic (3.13e-1)" PRSS37 ENSG00000165076 "Serine protease 37" A4D1T9 7 141836300-141841487 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 40.1" "Group enriched" "Detected in some" 158 "Early spermatids: 323.0;Late spermatids: 540.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA020541 Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 10: Testis - Spermatid development" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 21: Early spermatids - Spermatogenesis" "HPA020541: AB_1853004" "unprognostic (4.70e-2)" "unprognostic (5.56e-2)" "unprognostic (2.69e-1)" "unprognostic (2.41e-1)" "unprognostic (3.21e-2)" "unprognostic (1.30e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-2)" "unprognostic (8.30e-7)" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (2.72e-2)" PRSS38 MPN2 ENSG00000185888 "Serine protease 38" A1L453 1 227815675-227846470 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 40 "testis: 4.1" "Group enriched" "Detected in some" 14 "Spermatocytes: 32.9;Spermatogonia: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Enzyme NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (9.54e-3)" "unprognostic (3.61e-3)" PRSS48 ESSPL ENSG00000189099 "Serine protease 48" Q7RTY5 4 151277161-151291862 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.1;Oligodendrocyte precursor cells: 8.0;Oligodendrocytes: 3.4;Spermatocytes: 4.1;Spermatogonia: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053801 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 42: Choroid plexus - Mitochondria" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA053801: AB_2682267" "unprognostic (9.68e-2)" "unprognostic (1.35e-2)" "unprognostic (2.15e-1)" "unprognostic (2.18e-2)" "unprognostic (3.76e-2)" "unprognostic (4.10e-2)" PRSS50 "CT20, TSP50" ENSG00000283706 "Serine protease 50" Q9UI38 3 46712117-46717869 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pituitary gland: 16.7;testis: 50.6;thyroid gland: 16.0" "Cell type enhanced" "Detected in single" "Astrocytes: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "cervical cancer: 2.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA040768 Supported "Intracellular and membrane" Enzyme NA NA "Cluster 78: Testis - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 47: Astrocytes - Unknown function" "HPA040768: AB_2677126" PRSS51 ENSG00000253649 "Serine protease 51" A0A1B0GVH4 8 10482878-10547585 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "brain: 18.5" "Group enriched" "Detected in some" 9 "Cone photoreceptor cells: 1.7;Early spermatids: 4.1;Horizontal cells: 2.5;Late spermatids: 5.5;Oocytes: 5.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 61.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 9.7;Rhabdoid: 4.6" "Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in brain" "No annotated function" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 13: Spermatids - Transcription" "unprognostic (2.52e-1)" "unprognostic (3.00e-1)" "unprognostic (3.10e-1)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "unprognostic (2.22e-2)" "unprognostic (2.72e-1)" "unprognostic (7.48e-2)" "unprognostic (1.64e-1)" "unprognostic (7.94e-2)" "unprognostic (1.02e-1)" "unprognostic (6.33e-3)" "unprognostic (2.71e-3)" "unprognostic (7.47e-2)" "unprognostic (3.42e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" PRSS53 POL3S ENSG00000151006 "Serine protease 53" Q2L4Q9 16 31083437-31089628 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 9.7" "Group enriched" "Detected in some" 4 "Astrocytes: 1.5;Excitatory neurons: 6.1;Inhibitory neurons: 4.1;Leydig cells: 1.7;Oligodendrocytes: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034955, HPA034956" Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 83: Liver - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA034955: AB_2674380, HPA034956: AB_10696365" "unprognostic (3.13e-1)" "unprognostic (4.15e-1)" "unprognostic (3.88e-3)" "unprognostic (1.62e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-2)" "unprognostic (1.84e-1)" "unprognostic (2.63e-2)" "unprognostic (1.04e-2)" "unprognostic (2.87e-2)" "unprognostic (2.72e-2)" "unprognostic (1.63e-4)" "unprognostic (2.53e-12)" "unprognostic (1.02e-1)" "unprognostic (2.01e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" PRSS54 "CT67, FLJ25339, KLKBL4" ENSG00000103023 "Serine protease 54" Q6PEW0 16 58279997-58295047 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 285 "testis: 40.2" "Group enriched" "Detected in some" 45 "Early spermatids: 510.6;Late spermatids: 296.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA041549 Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 10: Testis - Spermatid development" "Cluster 17: Choroid plexus - Cilium" "Cluster 13: Spermatids - Transcription" "HPA041549: AB_10795640" "unprognostic (1.13e-1)" "unprognostic (3.24e-2)" "unprognostic (3.09e-2)" "unprognostic (3.08e-1)" "unprognostic (4.88e-2)" "unprognostic (1.23e-1)" PRSS55 "CT153, T-SP1, UNQ9391" ENSG00000184647 "Serine protease 55" Q6UWB4 8 10525532-10554166 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "testis: 27.0" "Cell type enriched" "Detected in some" 4 "Early spermatids: 344.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 18: Early spermatids - Unknown function" "unprognostic (3.64e-1)" "unprognostic (8.44e-3)" "unprognostic (6.10e-2)" "unprognostic (7.40e-2)" "unprognostic (6.23e-5)" "unprognostic (6.62e-2)" PRSS57 "PRSSL1, UNQ782" ENSG00000185198 "Serine protease 57" Q6UWY2 19 685546-695498 "Enzymes, Predicted secreted proteins" "Heparin-binding, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "bone marrow: 163.1" "Cell type enriched" "Detected in some" 6 "Erythroid cells: 69.2" "Cancer enriched" "Detected in single" 10 "pancreatic cancer: 2.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.9" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in single" 229 "Leukemia: 199.5" "Lung - Neutrophil_1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Enzyme NA NA "Cluster 41: Basophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 1: Erythroid cells - Oxygen transport" "unprognostic (2.89e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (3.99e-4)" "unprognostic (3.07e-1)" "unprognostic (1.33e-2)" "unprognostic (3.50e-2)" "unprognostic (4.04e-2)" "unprognostic (7.70e-2)" "unprognostic (3.80e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-2)" "unprognostic (8.16e-2)" "unprognostic (2.56e-2)" PRSS58 TRYX3 ENSG00000258223 "Serine protease 58" Q8IYP2 7 142252143-142258058 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 180 "testis: 25.1" "Group enriched" "Detected in some" 164 "Early spermatids: 272.6;Late spermatids: 504.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" Enzyme NA NA "Cluster 10: Testis - Spermatid development" "Cluster 11: Neuronal - Sensory perception" "Cluster 21: Early spermatids - Spermatogenesis" PRSS8 CAP1 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 238.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 303.3;Extravillous trophoblasts: 770.7;Proximal enterocytes: 331.5;Syncytiotrophoblasts: 632.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "cerebellum: 5.0;choroid plexus: 14.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in some" HPA030436 Uncertain "Secreted - unknown location" Enzyme NA NA 4400000 "Cluster 48: Stomach - Proteolysis" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840999-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "bone marrow: 2068.5" "Cell type enriched" "Detected in some" 5 "Erythroid cells: 18.7" "Cancer enhanced" "Detected in single" "stomach cancer: 1.0" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 8 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.0" "Cancer enriched" "Detected in some" 225 "Leukemia: 507.6" "Lung - Neutrophil_1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced Approved Vesicles,Cytosol "Secreted to blood" Enzyme NA NA 390000 "Cluster 6: Bone marrow - Innate immune response" "Cluster 33: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" Cytosol Vesicles "CAB017558: AB_2172317, HPA005938: AB_1855764" "unprognostic (2.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.83e-3)" "unprognostic (4.20e-1)" "unprognostic (3.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.98e-3)" "unprognostic (3.67e-2)" "unprognostic (8.62e-6)" "unprognostic (5.31e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" PRXL2A "Adrx, C10orf58, FAM213A, MGC4248, PAMM" ENSG00000122378 "Peroxiredoxin like 2A" Q9BRX8 10 80407829-80437115 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Antioxidant "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 391.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 389.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "plasmacytoid DC: 166.4" "Lineage enriched" "Detected in all" 10 "dendritic cells: 166.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009025, HPA024565" Enhanced "Secreted in other tissues" Other NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA009025: AB_1078312, HPA024565: AB_1845519" "unprognostic (1.73e-2)" "unprognostic (2.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.15e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-2)" "unprognostic (3.14e-1)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (7.01e-2)" "unprognostic (3.54e-2)" "unprognostic (2.83e-3)" "unprognostic (3.32e-3)" "unprognostic (3.55e-1)" "unprognostic (6.78e-2)" "unprognostic (1.80e-1)" "prognostic favorable (6.11e-4)" PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851251 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2972.6;Kupffer cells: 2365.8;Macrophages: 1682.9;monocytes: 2500.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11625.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Lung - Macrophages, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" Other NA NA 88000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 29: Monocytes - Innate immune response" 6 Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" PSAPL1 ENSG00000178597 "Prosaposin like 1" Q6NUJ1 4 7430285-7434930 "Predicted secreted proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 95.4;stomach 1: 37.6" "Cell type enriched" "Detected in some" 8 "Gastric mucus-secreting cells: 54.2" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.7;melanoma: 2.5;pancreatic cancer: 2.0;stomach cancer: 3.0;urothelial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.3;Esophageal cancer: 2.0" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038013, HPA038482" Approved Enhanced Cytosol "Secreted - unknown location" Other NA NA 31000 "Cluster 13: Skin - Cornification" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" Cytosol "HPA038013: AB_10673652, HPA038482: AB_2676037" "unprognostic (2.64e-2)" "unprognostic (2.40e-1)" "unprognostic (9.33e-2)" "unprognostic (2.40e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-3)" "unprognostic (2.52e-1)" "unprognostic (2.08e-2)" "unprognostic (2.75e-1)" "unprognostic (2.63e-3)" PSG1 "CD66f, PBG1, PSBG1, PSGGA" ENSG00000231924 "Pregnancy specific beta-1-glycoprotein 1" P11464 19 42866464-42879822 "CD markers, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 397 "placenta: 252.6" "Cell type enriched" "Detected in some" 92 "Syncytiotrophoblasts: 200.2" "Cancer enhanced" "Detected in single" "thyroid cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 173.3" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 75000000 "Cluster 58: Placenta - Pregnancy" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 "HPA046327: AB_2679624" "unprognostic (2.02e-1)" "unprognostic (3.54e-1)" "unprognostic (2.44e-7)" "unprognostic (2.28e-2)" PSG11 "MGC22484, PSG13, PSG14" ENSG00000243130 "Pregnancy specific beta-1-glycoprotein 11" Q9UQ72 19 43007656-43026474 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 87 "placenta: 51.3" "Cell type enriched" "Detected in some" 46 "Syncytiotrophoblasts: 151.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.5;Rhabdoid: 2.7;testis cancer: 1.8" "HPA042240, HPA046327" Enhanced "Secreted in female reproductive system" "No annotated function" NA NA 40000000 "Cluster 58: Placenta - Pregnancy" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA042240: AB_10797384, HPA046327: AB_2679624" "unprognostic (2.58e-1)" PSG2 "CEA, PSBG2, PSG1, PSGGB" ENSG00000242221 "Pregnancy specific beta-1-glycoprotein 2" P11465 19 43064209-43083045 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 247 "placenta: 231.6" "Cell type enriched" "Detected in some" 23 "Syncytiotrophoblasts: 753.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 9.1;testis cancer: 8.7" "Secreted in female reproductive system" "No annotated function" NA NA 41000000 "Cluster 58: Placenta - Pregnancy" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "unprognostic (1.02e-2)" PSG3 ENSG00000221826 "Pregnancy specific beta-1-glycoprotein 3" Q16557 19 42721638-42740481 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 199 "placenta: 137.4" "Cell type enriched" "Detected in some" 80 "Syncytiotrophoblasts: 1413.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.2;Rhabdoid: 2.9;thyroid cancer: 3.1" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 67000000 "Cluster 58: Placenta - Pregnancy" "Cluster 15: Kidney cancer - Membrane components" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA046327: AB_2679624" PSG4 ENSG00000243137 "Pregnancy specific beta-1-glycoprotein 4" Q00888 19 43192702-43207299 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "parathyroid gland: 53.8;placenta: 139.5" "Cell type enriched" "Detected in some" 41 "Syncytiotrophoblasts: 553.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 68.6" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 58000000 "Cluster 58: Placenta - Pregnancy" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA046327: AB_2679624" "unprognostic (4.29e-2)" "unprognostic (5.18e-2)" "unprognostic (9.49e-2)" "unprognostic (2.52e-2)" "unprognostic (3.63e-2)" "unprognostic (1.94e-1)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (7.75e-2)" "unprognostic (8.82e-3)" "unprognostic (1.03e-3)" "unprognostic (1.68e-2)" "unprognostic (2.85e-1)" "unprognostic (2.57e-1)" PSG5 "FL-NCA-3, PSG" ENSG00000204941 "Pregnancy specific beta-1-glycoprotein 5" Q15238 19 43166256-43186536 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 126 "placenta: 108.6" "Cell type enriched" "Detected in some" 38 "Syncytiotrophoblasts: 694.0" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 22000000 "Cluster 58: Placenta - Pregnancy" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 "HPA046327: AB_2679624" "unprognostic (1.59e-1)" "unprognostic (3.38e-2)" "unprognostic (4.69e-2)" "unprognostic (1.62e-2)" "unprognostic (2.18e-1)" "unprognostic (2.04e-1)" "unprognostic (1.75e-2)" "unprognostic (1.12e-2)" "unprognostic (2.62e-2)" "unprognostic (1.03e-1)" "unprognostic (7.92e-2)" PSG6 ENSG00000170848 "Pregnancy specific beta-1-glycoprotein 6" Q00889 19 42902086-42919563 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "placenta: 48.0" "Cell type enriched" "Detected in some" 120 "Syncytiotrophoblasts: 376.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 9.6;testis cancer: 3.6" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 65000000 "Cluster 58: Placenta - Pregnancy" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA046327: AB_2679624" "unprognostic (4.23e-1)" PSG7 ENSG00000221878 "Pregnancy specific beta-1-glycoprotein 7" Q13046 19 42924132-42937207 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "placenta: 4.0;skin 1: 1.2" "Cell type enriched" "Detected in some" 75 "Syncytiotrophoblasts: 128.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 6.5" "Skin - Keratinocyte (granular)" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA046327: AB_2679624" PSG8 ENSG00000124467 "Pregnancy specific beta-1-glycoprotein 8" Q9UQ74 19 42752686-42765678 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "placenta: 6.3" "Cell type enriched" "Detected in some" 11 "Syncytiotrophoblasts: 38.7" "Cancer enriched" "Detected in single" 17 "thyroid cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.0;Rhabdoid: 1.7" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 55000000 "Cluster 58: Placenta - Pregnancy" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA046327: AB_2679624" "unprognostic (1.85e-2)" PSG9 "PSG11, PSGII" ENSG00000183668 "Pregnancy specific beta-1-glycoprotein 9" Q00887 19 43211791-43269530 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 136 "placenta: 103.4" "Cell type enriched" "Detected in some" 25 "Syncytiotrophoblasts: 219.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Bladder cancer: 6.6;breast cancer: 22.3;liver cancer: 7.5;Rhabdoid: 26.1;testis cancer: 9.8" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA 43000000 "Cluster 58: Placenta - Pregnancy" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA046327: AB_2679624" "unprognostic (9.32e-2)" "unprognostic (3.28e-1)" "unprognostic (2.15e-1)" PSORS1C2 "C6orf17, SPR1" ENSG00000204538 "Psoriasis susceptibility 1 candidate 2" Q9UIG4 6 31137534-31139066 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "skin 1: 182.3" "Group enriched" "Detected in some" 8 "Glandular and luminal cells: 7.8;Melanocytes: 10.3;Suprabasal keratinocytes: 7.4" "Cancer enhanced" "Detected in many" "testis cancer: 14.6;urothelial cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA061228 Enhanced "Secreted in other tissues" "No annotated function" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 18 "HPA061228: AB_2684455" "unprognostic (8.86e-2)" "unprognostic (7.73e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-2)" "unprognostic (5.20e-3)" "unprognostic (1.67e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (3.78e-1)" "unprognostic (1.64e-2)" "unprognostic (1.06e-1)" "unprognostic (9.40e-5)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (2.66e-1)" PSPN PSP ENSG00000125650 Persephin O60542 19 6375148-6379058 "Predicted secreted proteins" "Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Late spermatids: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB025366 Uncertain "Secreted in other tissues" "Growth factor" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" "CAB025366: " "unprognostic (3.21e-1)" "unprognostic (3.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" "unprognostic (3.67e-1)" "unprognostic (2.05e-2)" "unprognostic (5.80e-3)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (6.27e-2)" "unprognostic (1.54e-6)" "unprognostic (5.39e-3)" "unprognostic (1.01e-3)" "unprognostic (4.25e-2)" "unprognostic (2.26e-1)" "unprognostic (2.44e-1)" "unprognostic (1.60e-1)" PTEN "BZS, MHAM, MMAC1, PTEN1, TEP1" ENSG00000171862 "Phosphatase and tensin homolog" P60484 10 87862563-87971930 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Lipid metabolism, Neurogenesis" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 63.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Prostate - Fibroblasts, Testis - Early spermatids" "CAB004076, HPA031335, CAB080153, CAB080155, CAB080157" Approved Supported Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 48: Smooth muscle cells - Signal transduction" 16 Cytosol Nucleoplasm "CAB004076: AB_390810, CAB080153: , CAB080155: , CAB080157: , HPA031335: AB_2797221" "unprognostic (8.72e-2)" "unprognostic (2.45e-1)" "unprognostic (5.43e-1)" "unprognostic (1.50e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.18e-1)" "unprognostic (2.08e-1)" "unprognostic (2.07e-1)" "unprognostic (6.87e-2)" "unprognostic (9.77e-2)" "unprognostic (2.71e-1)" "prognostic unfavorable (7.35e-4)" "unprognostic (1.57e-1)" "unprognostic (2.73e-1)" "unprognostic (6.54e-3)" "unprognostic (2.41e-1)" PTGDS "L-PGDS, PGDS" ENSG00000107317 "Prostaglandin D2 synthase" P41222 9 136975092-136981742 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Mast cell degranulation, Prostaglandin biosynthesis, Prostaglandin metabolism, Transport" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 3326.0;heart muscle: 4736.0;testis: 3152.4" "Group enriched" "Detected in many" 11 "Leydig cells: 30511.4;Peritubular cells: 48944.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 27 "plasmacytoid DC: 1389.8" "Lineage enriched" "Detected in many" 27 "dendritic cells: 1389.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 82.1" "Heart muscle - Cardiomyocytes, Kidney - Podocytes, Liver - Hepatic stellate cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "HPA004938, CAB009916, HPA067456" Uncertain "Secreted to blood" Transport NA NA 2500000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 6: Ovarian stromal cells - Transcription" 10 "CAB009916: AB_2174617, HPA004938: AB_1855745, HPA067456: " "unprognostic (2.79e-2)" "unprognostic (3.96e-3)" "unprognostic (9.70e-2)" "unprognostic (5.71e-3)" "unprognostic (6.50e-2)" "unprognostic (1.43e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-2)" "unprognostic (1.95e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.19e-7)" "unprognostic (8.49e-3)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (3.21e-2)" PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 104.6;skin 1: 148.5;urinary bladder: 169.2" "Group enriched" "Detected in many" 4 "Glandular and luminal cells: 178.4;granulocytes: 193.1" "Cancer enhanced" "Detected in all" "ovarian cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 28.8" "Group enriched" "Detected in many" 6 "dendritic cells: 20.0;granulocytes: 28.8;monocytes: 13.1" "Cancer enhanced" "Detected in many" "cervical cancer: 32.5;ovarian cancer: 30.4" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002834, CAB020315" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 2100000 "Cluster 29: Non-specific - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "Golgi apparatus" Vesicles "CAB020315: , HPA002834: AB_1079711" "unprognostic (4.20e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (5.88e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-3)" "unprognostic (3.32e-1)" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (4.03e-2)" "unprognostic (1.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.35e-4)" PTGS2 COX2 ENSG00000073756 "Prostaglandin-endoperoxide synthase 2" P35354 1 186671791-186680922 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 115.6;seminal vesicle: 123.1;urinary bladder: 156.5" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 225.6;Basal prostatic cells: 712.9;granulocytes: 577.7;Langerhans cells: 383.2;Macrophages: 272.0;monocytes: 363.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "neutrophil: 11.8" "Lineage enriched" "Detected in single" 16 "granulocytes: 11.8" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts" "Region enhanced" "Detected in many" "hippocampal formation: 15.1" "Low region specificity" "Detected in all" "CAB000113, HPA001335, CAB080135" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Basal prostatic cells - Lipid metabolism" "CAB000113: , CAB080135: , HPA001335: AB_1079712" "unprognostic (1.36e-3)" "unprognostic (9.97e-3)" "unprognostic (3.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (9.50e-2)" "unprognostic (9.03e-3)" "unprognostic (2.81e-1)" "unprognostic (3.24e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (8.04e-3)" "unprognostic (4.38e-2)" "unprognostic (8.89e-2)" "unprognostic (3.74e-2)" PTH PTH1 ENSG00000152266 "Parathyroid hormone" P01270 11 13492054-13496181 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 243 "parathyroid gland: 48480.1" "Cell type enhanced" "Detected in single" "Oligodendrocytes: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000072, CAB023409, CAB026363, HPA048540" Enhanced "Secreted to blood" Hormone NA NA 28000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" 1 "CAB000072: , CAB023409: AB_619175, CAB026363: , HPA048540: AB_2680435" PTH2 TIP39 ENSG00000142538 "Parathyroid hormone 2" Q96A98 19 49422419-49423441 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.0" "Cell type enriched" "Detected in some" 4 "Oocytes: 13.2" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.0" "Region enriched" "Detected in single" 10 "olfactory bulb: 2.9" "Low region specificity" "Detected in all" "Secreted in brain" Neuropeptide NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 6: Leukemia - Signal transduction" "Cluster 44: Oocytes - Unknown function" "unprognostic (3.41e-1)" PTHLH "HHM, PLP, PTHR, PTHRP" ENSG00000087494 "Parathyroid hormone like hormone" P12272 12 27958084-27972733 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 21.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 228.4;Basal squamous epithelial cells: 48.8;Breast glandular cells: 101.0;Breast myoepithelial cells: 39.0;Club cells: 47.1;Ionocytes: 56.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 243.3" "Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035982 Approved Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted in other tissues" Hormone NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA035982: AB_10794631" "unprognostic (1.67e-1)" "unprognostic (5.26e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (1.60e-2)" "unprognostic (1.18e-1)" "unprognostic (5.16e-2)" "unprognostic (4.09e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-9)" "unprognostic (2.01e-2)" "unprognostic (1.34e-1)" "unprognostic (5.23e-3)" "unprognostic (7.87e-3)" PTK7 CCK4 ENSG00000112655 "Protein tyrosine kinase 7 (inactive)" Q13308 6 43076307-43161719 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 150.8;Endometrial stromal cells: 76.3;Late spermatids: 188.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 68.9" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 13.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 13.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003222 Approved "Secreted to blood" Receptor NA NA 12000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 21: Early spermatids - Spermatogenesis" 6 "HPA003222: AB_1079713" "unprognostic (1.80e-1)" "unprognostic (7.49e-3)" "unprognostic (6.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.65e-1)" "unprognostic (1.15e-2)" "unprognostic (5.85e-3)" "unprognostic (9.81e-3)" "unprognostic (1.47e-3)" "unprognostic (7.15e-2)" "unprognostic (5.11e-3)" "unprognostic (8.17e-2)" "unprognostic (3.37e-2)" "unprognostic (1.73e-1)" "unprognostic (3.61e-1)" "unprognostic (9.12e-2)" "unprognostic (5.70e-3)" PTN "HBGF8, HBNF, NEGF1" ENSG00000105894 Pleiotrophin P21246 7 137227341-137343774 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 376.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 694.6;Extravillous trophoblasts: 495.0;Muller glia cells: 482.6;Squamous epithelial cells: 472.6" "Cancer enriched" "Detected in all" 11 "glioma: 514.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 134.7;Neuroblastoma: 73.5" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017685, HPA073913" Enhanced Supported "Endoplasmic reticulum" "Secreted to blood" "Growth factor" NA NA 167000 1400000 "Cluster 61: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 9: Endometrial stromal cells - Transcription" 10 "Endoplasmic reticulum" "CAB017685: AB_1128556, HPA073913: " "unprognostic (1.51e-2)" "unprognostic (7.87e-2)" "unprognostic (5.44e-2)" "unprognostic (4.23e-2)" "unprognostic (1.92e-1)" "unprognostic (7.19e-2)" "unprognostic (2.81e-2)" "unprognostic (7.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.09e-2)" "unprognostic (3.86e-1)" "unprognostic (1.22e-2)" "prognostic favorable (1.35e-4)" "unprognostic (2.34e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 286.2" "Cell type enhanced" "Detected in many" "B-cells: 499.8;Macrophages: 517.0;monocytes: 1920.1;NK-cells: 1334.0;T-cells: 1095.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 84.8;lymphoma: 127.0" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Skin - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221, CAB080251" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 24000000 "Cluster 28: Neutrophils - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 6 "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, CAB080251: , HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" PTPRCAP "CD45-AP, LPAP" ENSG00000213402 "Protein tyrosine phosphatase receptor type C associated protein" Q14761 11 67435510-67437682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 77.5;lymphoid tissue: 170.0" "Group enriched" "Detected in some" 6 "B-cells: 173.1;Plasma cells: 176.1;T-cells: 138.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 111 "Leukemia: 246.1;lymphoma: 323.7;Myeloma: 81.4" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "Low region specificity" "Detected in many" HPA043734 Enhanced Approved "Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 7: T-cells - T-cell receptor" 1 "Plasma membrane" "HPA043734: AB_10962214" PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase receptor type D" P23468 9 8314246-10613002 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.5;parathyroid gland: 17.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 4422.9;Inhibitory neurons: 1105.1;Oligodendrocyte precursor cells: 1098.0;Oligodendrocytes: 2932.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 21.5" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" Receptor NA NA 20000000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 11: White matter - Signal transduction" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 2 Vesicles Nucleoplasm "HPA054829: AB_2682618" "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" PTPRF LAR ENSG00000142949 "Protein tyrosine phosphatase receptor type F" P10586 1 43525187-43623666 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 335.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012710 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" Receptor NA NA 160000000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Golgi apparatus" "HPA012710: AB_1855933" "unprognostic (8.20e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-2)" "unprognostic (9.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (4.59e-1)" "unprognostic (1.51e-1)" "unprognostic (4.97e-2)" "unprognostic (4.68e-2)" "unprognostic (7.07e-2)" "unprognostic (1.99e-2)" "prognostic favorable (7.03e-4)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.58e-1)" PTPRJ "CD148, DEP1, HPTPeta" ENSG00000149177 "Protein tyrosine phosphatase receptor type J" Q12913 11 47980425-48170839 "CD markers, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 160.4;Microglial cells: 180.7;monocytes: 104.5;Oligodendrocyte precursor cells: 225.0;Oligodendrocytes: 156.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 4 "granulocytes: 9.5;monocytes: 4.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Lung - Neutrophil_2, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006026 Approved "Intracellular and membrane" Enzyme NA NA 670000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 8 "HPA006026: AB_1078446" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-2)" "unprognostic (3.20e-2)" "unprognostic (2.99e-2)" "unprognostic (6.58e-2)" "unprognostic (2.15e-1)" "unprognostic (9.64e-3)" "unprognostic (3.79e-3)" "unprognostic (5.16e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.13e-5)" "unprognostic (1.09e-2)" "unprognostic (7.98e-2)" "unprognostic (9.18e-2)" "unprognostic (2.00e-1)" PTPRO "GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2" ENSG00000151490 "Protein tyrosine phosphatase receptor type O" Q16827 12 15322257-15602175 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.4;intestine: 26.0;kidney: 35.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 187.1;Horizontal cells: 53.5;Inhibitory neurons: 220.1;Oligodendrocyte precursor cells: 118.9;Undifferentiated cells: 50.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.0;Gastric cancer: 5.9" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Liver - Kupffer cells" "Region enhanced" "Detected in all" "olfactory bulb: 175.9" "Low region specificity" "Detected in all" HPA034525 Enhanced "Intracellular and membrane" Receptor NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 52: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA034525: AB_10669785" "unprognostic (3.68e-2)" "unprognostic (3.49e-1)" "unprognostic (9.64e-2)" "unprognostic (1.25e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-1)" "unprognostic (5.93e-3)" "unprognostic (5.37e-2)" "unprognostic (2.03e-1)" "unprognostic (3.72e-2)" "unprognostic (2.00e-1)" "unprognostic (5.43e-2)" "unprognostic (4.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" PTPRS ENSG00000105426 "Protein tyrosine phosphatase receptor type S" Q13332 19 5158495-5340812 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 51.1;Excitatory neurons: 74.2;Horizontal cells: 50.4;Inhibitory neurons: 100.0;Oligodendrocyte precursor cells: 67.4;Oligodendrocytes: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 197 "plasmacytoid DC: 153.7" "Lineage enriched" "Detected in single" 197 "dendritic cells: 153.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" Receptor NA NA 150000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 69: Neurons - Neuronal signaling" 1 "Plasma membrane, Cytosol" "HPA054747: AB_2682591" "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 156.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 2547.0" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 21.7;skin cancer: 27.8" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" Enzyme NA NA 3400000 "Cluster 33: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 69: Skin cancer - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" 3 Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavorable (9.36e-4)" PTX3 "TNFAIP5, TSG-14" ENSG00000163661 "Pentraxin 3" P26022 3 157436850-157443633 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 224.0;urinary bladder: 184.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 113.5;Lymphatic endothelial cells: 60.2;Macrophages: 42.4;monocytes: 255.0;Secretory cells: 122.6" "Cancer enhanced" "Detected in many" "glioma: 22.5" "Region enhanced" "Detected in many" "thalamus: 9.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 203.9" "Skin - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069320 Approved Uncertain "Plasma membrane" "Secreted to blood" "No annotated function" NA NA 1090000 970000 "Cluster 19: Eosinophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 29: Monocytes - Innate immune response" 4 "Plasma membrane" "HPA069320: AB_2686118" "unprognostic (1.93e-2)" "unprognostic (4.96e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (8.35e-9)" "unprognostic (5.79e-3)" "prognostic unfavorable (6.36e-4)" "unprognostic (6.03e-3)" "prognostic unfavorable (8.75e-6)" "unprognostic (2.45e-1)" "unprognostic (6.69e-2)" "unprognostic (7.60e-2)" "unprognostic (2.63e-1)" "unprognostic (2.76e-9)" "unprognostic (6.03e-3)" "unprognostic (5.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.92e-3)" PTX4 C16orf38 ENSG00000251692 "Pentraxin 4" Q96A99 16 1485886-1488981 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Leukemia: 1.1" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Low region specificity" "Detected in all" HPA073694 Supported "Secreted - unknown location" "No annotated function" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "HPA073694: AB_2732237" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (1.12e-1)" "unprognostic (1.84e-4)" "unprognostic (3.98e-2)" "unprognostic (5.66e-2)" "unprognostic (1.10e-1)" "unprognostic (3.09e-1)" "unprognostic (1.39e-2)" "unprognostic (3.54e-1)" "unprognostic (1.52e-4)" "unprognostic (2.23e-3)" "unprognostic (4.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.03e-1)" PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.4;intermediate monocyte: 4.4;myeloid DC: 3.6;neutrophil: 1.4;non-classical monocyte: 5.1" "Group enriched" "Detected in many" 4 "dendritic cells: 3.6;granulocytes: 1.4;monocytes: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" Receptor NA NA 720000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 52 "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: AB_1846248, HPA064739: " "unprognostic (2.90e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (7.89e-2)" "unprognostic (2.45e-3)" "unprognostic (3.06e-2)" "prognostic unfavorable (9.30e-4)" "unprognostic (9.05e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-3)" "unprognostic (1.69e-1)" "unprognostic (4.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "prognostic unfavorable (2.75e-4)" PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 74.7;Endometrial stromal cells: 98.6;Endothelial cells: 65.3;Fibroblasts: 54.4;Oligodendrocyte precursor cells: 52.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 51.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 181.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA012375 Approved "Secreted to extracellular matrix" Enzyme NA NA 9100000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" PXDNL "FLJ25471, PMR1" ENSG00000147485 "Peroxidasin like" A1KZ92 8 51319577-51809445 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 43.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 53.1;Early spermatids: 55.2;Excitatory neurons: 24.3;Inhibitory neurons: 66.4;Microglial cells: 16.1;Spermatocytes: 19.5" "Group enriched" "Detected in some" 4 "breast cancer: 1.7;glioma: 0.7;renal cancer: 0.8;testis cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Testis - Early spermatids" HPA007919 Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 8: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA007919: AB_1855966" "prognostic unfavorable (3.27e-5)" "unprognostic (4.59e-4)" "unprognostic (5.57e-3)" "unprognostic (2.83e-3)" "unprognostic (2.71e-1)" "unprognostic (5.14e-2)" "unprognostic (1.18e-1)" "unprognostic (7.18e-3)" "unprognostic (1.85e-1)" "unprognostic (1.15e-1)" "unprognostic (7.07e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-4)" "unprognostic (2.28e-2)" "unprognostic (3.35e-2)" "unprognostic (2.42e-2)" "unprognostic (2.97e-4)" PXYLP1 "ACPL2, FLJ23751" ENSG00000155893 "2-phosphoxylose phosphatase 1" Q8TE99 3 141228726-141367753 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 144.7" "Cell type enhanced" "Detected in many" "Early spermatids: 206.6;Late spermatids: 139.2;Spermatocytes: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017243 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 59: Leukemia - T-cell receptor" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA017243: AB_1844509" "unprognostic (9.55e-2)" "unprognostic (3.48e-3)" "unprognostic (1.81e-1)" "unprognostic (2.06e-1)" "unprognostic (8.45e-2)" "unprognostic (8.04e-3)" "unprognostic (4.05e-3)" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (6.95e-2)" "unprognostic (5.07e-3)" "unprognostic (4.67e-2)" "unprognostic (1.29e-2)" "unprognostic (5.20e-2)" "unprognostic (1.37e-1)" "unprognostic (8.56e-2)" "unprognostic (8.17e-3)" PYY PYY1 ENSG00000131096 "Peptide YY" P10082 17 43952733-44004469 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "intestine: 68.4" "Cell type enriched" "Detected in some" 136 "Enteroendocrine cells: 14671.0" "Group enriched" "Detected in many" 8 "endometrial cancer: 7.9;ovarian cancer: 15.2;testis cancer: 18.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "liver cancer: 9.9;Neuroblastoma: 2.7" "Colon - Colon enterocytes" "Region enriched" "Detected in single" 14 "pons and medulla: 1.4" "Low region specificity" "Detected in some" "HPA010973, CAB016734" Enhanced "Secreted to blood" Hormone NA NA 87100 "Cluster 45: Intestine - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 20: Enteroendocrine cells - Hormone signaling" "CAB016734: AB_876471, HPA010973: AB_1855194" "unprognostic (8.17e-3)" "unprognostic (5.41e-2)" "unprognostic (9.93e-2)" "unprognostic (1.81e-3)" "unprognostic (2.48e-4)" "unprognostic (5.26e-2)" "unprognostic (4.14e-2)" "unprognostic (1.80e-2)" "unprognostic (1.75e-2)" "unprognostic (1.54e-2)" "unprognostic (2.91e-1)" "unprognostic (1.29e-1)" "unprognostic (5.69e-3)" "unprognostic (3.77e-2)" "unprognostic (1.79e-1)" "unprognostic (1.41e-1)" "unprognostic (1.20e-1)" PZP CPAMD6 ENSG00000126838 "PZP alpha-2-macroglobulin like" P20742 12 9148840-9208395 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "liver: 79.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 12.1;Early spermatids: 28.3;Hepatocytes: 22.5;Late spermatids: 11.4;Oligodendrocyte precursor cells: 8.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.0;liver cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.1;MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 11 "T-cells: 1.1" "Cancer enriched" "Detected in single" 9 "cervical cancer: 1.9" "Adipose subcutaneous - Endothelial cells, Lung - Respiratory ciliated cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "HPA041403, HPA041471" Supported "Secreted to blood" "Enzyme inhibitor" NA NA 15000000000 "Cluster 1: T-cells - Unknown function" "Cluster 31: Liver - Plasma proteins" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 42: Ciliated cells - Cilium assembly" "HPA041403: AB_10804003, HPA041471: AB_10795636" "unprognostic (8.48e-3)" "unprognostic (1.12e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-4)" "unprognostic (4.79e-1)" "unprognostic (3.50e-2)" "unprognostic (2.04e-4)" "unprognostic (4.57e-2)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (9.71e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-5)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (9.81e-3)" QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37342827-37373322 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 165.0;epididymis: 101.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 89.9;Langerhans cells: 176.0;Melanocytes: 659.7;Pancreatic endocrine cells: 151.1" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 1536.9" "Lineage enriched" "Detected in many" 4 "granulocytes: 1536.9" "Group enriched" "Detected in all" 6 "Myeloma: 99.3;skin cancer: 291.9" "Lung - Neutrophil_2, Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" Enzyme NA NA 390000 "Cluster 21: Neutrophils - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 1 Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29663279-29698699 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 115.0;liver: 179.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 422.5;Extravillous trophoblasts: 351.0;Hepatocytes: 372.3;Proximal tubular cells: 527.4;Syncytiotrophoblasts: 192.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 4.3;intermediate monocyte: 5.3;myeloid DC: 5.9;non-classical monocyte: 9.1;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 5.9;monocytes: 9.1" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA011887, HPA076010" Enhanced Approved Vesicles "Intracellular and membrane" Enzyme NA NA 780000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 2 Vesicles "HPA011887: AB_2668555, HPA076010: " "prognostic unfavorable (5.10e-5)" "unprognostic (2.00e-1)" "unprognostic (9.48e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (9.31e-4)" "unprognostic (1.44e-2)" "unprognostic (8.75e-2)" "unprognostic (1.22e-1)" "unprognostic (8.16e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (6.81e-2)" "unprognostic (3.37e-2)" "unprognostic (1.33e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-2)" QRFP "26RFa, P518, prepro-26RFa" ENSG00000188710 "Pyroglutamylated RFamide peptide" P83859 9 130892707-130896812 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.8;Horizontal cells: 1.9;Prostatic glandular cells: 1.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.0" "Lineage enriched" "Detected in single" 11 "monocytes: 1.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043377 Uncertain "Secreted in other tissues" Neuropeptide NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA043377: AB_10959754" "unprognostic (1.79e-3)" "unprognostic (1.01e-1)" "unprognostic (2.28e-3)" "unprognostic (4.14e-3)" "unprognostic (7.78e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-3)" "unprognostic (5.11e-3)" "unprognostic (1.77e-1)" "unprognostic (2.28e-1)" "unprognostic (5.43e-3)" "unprognostic (1.02e-1)" "unprognostic (2.52e-2)" "unprognostic (2.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.65e-1)" "unprognostic (7.04e-3)" QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Extravillous trophoblasts: 1872.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" Enzyme NA NA 2600000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 4: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" QSOX2 "DKFZp762A2013, QSCN6L1, SOXN" ENSG00000165661 "Quiescin sulfhydryl oxidase 2" Q6ZRP7 9 136206333-136245812 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012716, HPA017280" Uncertain Supported "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 9600000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 73: B-cells - B-cell function" "Golgi apparatus" Nucleoplasm "HPA012716: AB_2173315, HPA017280: AB_2669565" "unprognostic (7.29e-2)" "unprognostic (7.35e-3)" "unprognostic (6.23e-2)" "unprognostic (5.28e-2)" "unprognostic (1.49e-1)" "unprognostic (4.46e-3)" "unprognostic (1.10e-3)" "unprognostic (4.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.06e-3)" "unprognostic (5.96e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (9.64e-6)" "unprognostic (1.23e-2)" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (1.10e-2)" R3HCC1 DKFZp564N123 ENSG00000104679 "R3H domain and coiled-coil containing 1" Q9Y3T6 8 23270120-23296279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 103.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023073, HPA023153" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" "No annotated function" Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" Cytosol Nucleoplasm "HPA023073: AB_1855987, HPA023153: AB_2237834" "unprognostic (5.80e-2)" "unprognostic (4.70e-3)" "prognostic favorable (4.08e-4)" "unprognostic (7.46e-3)" "unprognostic (1.97e-1)" "unprognostic (7.26e-2)" "unprognostic (8.49e-3)" "unprognostic (1.02e-2)" "unprognostic (7.73e-2)" "unprognostic (2.92e-1)" "prognostic favorable (8.66e-4)" "unprognostic (7.65e-2)" "prognostic favorable (6.80e-5)" "unprognostic (1.22e-2)" "unprognostic (1.17e-1)" "unprognostic (4.18e-1)" "unprognostic (3.43e-1)" R3HDML dJ881L22.3 ENSG00000101074 "R3H domain containing like" Q9H3Y0 20 44337043-44351238 "Predicted secreted proteins" "Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "intestine: 2.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 5.3" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA070264 Enhanced "Secreted - unknown location" "Enzyme inhibitor" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 34: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "HPA070264: AB_2686244" "unprognostic (1.89e-1)" "unprognostic (2.23e-1)" "unprognostic (9.86e-2)" "unprognostic (9.12e-2)" "unprognostic (6.06e-3)" "unprognostic (2.64e-1)" "unprognostic (6.32e-2)" "unprognostic (4.95e-3)" RAB26 ENSG00000167964 "RAB26, member RAS oncogene family" Q9ULW5 16 2140803-2154165 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 110.2;liver: 44.8;pancreas: 41.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 38.8;Enteroendocrine cells: 52.7;Excitatory neurons: 50.2;Inhibitory neurons: 27.1;Intestinal goblet cells: 37.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 17.2" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075624 Uncertain "Vesicles,Plasma membrane,Cell Junctions,Centrosome,Cytosol" "Intracellular and membrane" Transport No No "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" 4 "Plasma membrane, Centrosome" "Vesicles, Cell Junctions, Cytosol" "HPA075624: " "unprognostic (1.01e-2)" "prognostic favorable (8.20e-5)" "unprognostic (7.25e-2)" "unprognostic (1.52e-1)" "unprognostic (7.34e-2)" "unprognostic (9.41e-3)" "unprognostic (2.81e-2)" "unprognostic (5.10e-2)" "unprognostic (1.82e-2)" "unprognostic (3.55e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (6.48e-2)" "unprognostic (5.68e-2)" "unprognostic (1.23e-1)" "unprognostic (7.16e-2)" "unprognostic (2.92e-3)" RAB9B RAB9L ENSG00000123570 "RAB9B, member RAS oncogene family" Q9NP90 X 103822327-103832257 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 20.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 102.9;Excitatory neurons: 27.5;Muller glia cells: 25.1;Oligodendrocyte precursor cells: 35.4;Peritubular cells: 29.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.8" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061932 Approved "Intracellular and membrane" Transport NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA061932: AB_2684640" "unprognostic (1.69e-2)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (7.28e-5)" "unprognostic (5.81e-2)" "unprognostic (3.89e-2)" "unprognostic (8.40e-2)" "unprognostic (1.42e-2)" "unprognostic (8.34e-2)" "unprognostic (8.29e-2)" "unprognostic (3.52e-4)" "unprognostic (1.10e-1)" "unprognostic (9.21e-4)" "unprognostic (1.37e-3)" "unprognostic (2.09e-1)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" RAET1E "bA350J20.7, LETAL, ULBP4" ENSG00000164520 "Retinoic acid early transcript 1E" Q8TD07 6 149883179-149898113 "Predicted intracellular proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 14.8;esophagus: 41.0;vagina: 19.9" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 92.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "cervical cancer: 23.1" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Skin - Keratinocyte (other), Testis - Late spermatids" HPA054022 Supported "Focal adhesion sites,Cytosol" "Intracellular and membrane" Immunity NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Focal adhesion sites" Cytosol "HPA054022: AB_2797250" "unprognostic (1.67e-2)" "unprognostic (2.10e-1)" "unprognostic (3.49e-3)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (1.36e-3)" "unprognostic (4.80e-4)" "unprognostic (1.11e-1)" "unprognostic (3.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (7.47e-5)" "unprognostic (2.41e-2)" "unprognostic (3.18e-2)" "unprognostic (3.17e-2)" "unprognostic (1.06e-1)" RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.1;esophagus: 14.6" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 40.8;Mesothelial cells: 51.1;Suprabasal keratinocytes: 40.0" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 23.7" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" Immunity NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 161.1;parathyroid gland: 375.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 488.2;Inhibitory neurons: 186.2;Microglial cells: 132.4;Oligodendrocytes: 596.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Other NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Oligodendrocytes - Unknown function" Nucleoplasm "Nuclear bodies" "HPA057821: AB_2683538, HPA076772: AB_2686814" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (5.22e-2)" "prognostic favorable (3.52e-5)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (3.76e-2)" "unprognostic (6.36e-3)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (8.26e-3)" RARRES1 "LXNL, TIG1" ENSG00000118849 "Retinoic acid receptor responder 1" P49788 3 158696892-158732489 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 214.9;fallopian tube: 199.7" "Cell type enhanced" "Detected in many" "Club cells: 974.1;Ionocytes: 374.4;Mesothelial cells: 1729.6;Mucus glandular cells: 959.1;Salivary duct cells: 787.8" "Cancer enhanced" "Detected in all" "urothelial cancer: 93.7" "Region enriched" "Detected in all" 4 "choroid plexus: 28.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Bile duct cancer: 62.0;breast cancer: 207.5;pancreatic cancer: 67.3" "Lung - Fibroblast_2, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003892 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Golgi apparatus" "Endoplasmic reticulum" "HPA003892: AB_1856079" "unprognostic (5.76e-3)" "unprognostic (2.13e-1)" "unprognostic (8.85e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (9.29e-4)" "unprognostic (7.09e-2)" "unprognostic (8.93e-2)" "unprognostic (3.86e-1)" "unprognostic (7.16e-3)" "unprognostic (1.47e-2)" "unprognostic (6.42e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.88e-6)" "unprognostic (3.49e-1)" "unprognostic (1.33e-1)" "unprognostic (7.73e-2)" "unprognostic (1.15e-1)" RARRES2 "HP10433, TIG2" ENSG00000106538 "Retinoic acid receptor responder 2" Q99969 7 150338317-150341662 "Plasma proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 2325.9;choroid plexus: 1575.8;liver: 1945.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 584.4;Hepatocytes: 2568.2;Mesothelial cells: 614.1;Muller glia cells: 667.6;Ovarian stromal cells: 698.5" "Cancer enhanced" "Detected in all" "liver cancer: 420.2" "Region enriched" "Detected in all" 8 "choroid plexus: 596.7" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in single" 8 "dendritic cells: 5.4" "Cancer enhanced" "Detected in many" "Kidney cancer: 575.4" "Lung - Fibroblast_1, Pancreas - Exocrine glandular cells, Prostate - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Other NA NA 75000000 460000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Hepatocytes - Metabolism" "unprognostic (1.96e-1)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (2.72e-2)" "unprognostic (2.82e-3)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (5.29e-2)" "unprognostic (2.50e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.83e-4)" "unprognostic (2.94e-2)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (5.17e-2)" RASA2 GAP1M ENSG00000155903 "RAS p21 protein activator 2" Q15283 3 141487027-141615344 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 167.1;Excitatory neurons: 190.2;NK-cells: 142.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035374, HPA035375" Approved Approved Vesicles "Intracellular and membrane" Other NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 16: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Vesicles "HPA035374: AB_10602122, HPA035375: AB_2674596" "unprognostic (1.85e-1)" "unprognostic (8.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.38e-2)" "unprognostic (1.18e-1)" "unprognostic (3.36e-3)" "unprognostic (9.62e-3)" "unprognostic (2.57e-1)" "unprognostic (1.38e-1)" "unprognostic (9.21e-2)" "unprognostic (4.23e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (7.62e-7)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.34e-5)" RASL11A ENSG00000122035 "RAS like family 11 member A" Q6T310 13 27270830-27275192 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 38.9;monocytes: 33.8;Smooth muscle cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA004859, HPA053296" Supported Approved "Nuclear bodies" "Intracellular and membrane" Transcription Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Nuclear bodies" "HPA004859: AB_2667270, HPA053296: AB_2682106" "unprognostic (1.59e-1)" "unprognostic (9.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (2.09e-2)" "unprognostic (6.65e-2)" "prognostic favorable (5.43e-4)" "unprognostic (3.85e-1)" "unprognostic (7.98e-2)" "unprognostic (2.65e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.52e-4)" "unprognostic (1.49e-1)" "unprognostic (2.54e-1)" "unprognostic (3.71e-2)" "unprognostic (3.34e-1)" RBP3 "D10S64, D10S65, D10S66, RP66" ENSG00000265203 "Retinol binding protein 3" P10745 10 47348363-47357881 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transport "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 179 "retina: 525.9" "Group enriched" "Detected in some" 11 "Bipolar cells: 444.0;Cone photoreceptor cells: 1364.4;Rod photoreceptor cells: 1741.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA041301, HPA044239" Enhanced "Secreted in other tissues" Transport NA NA "Cluster 76: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 9 "HPA041301: AB_2677398, HPA044239: AB_2678868" "unprognostic (3.48e-2)" "unprognostic (4.78e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.58e-2)" "unprognostic (5.09e-2)" "unprognostic (5.14e-3)" "unprognostic (7.44e-2)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" RBP4 ENSG00000138207 "Retinol binding protein 4" P02753 10 93591687-93601744 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Sensory transduction, Transport, Vision" "Cancer-related genes, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "liver: 10726.7" "Cell type enriched" "Detected in many" 13 "Hepatocytes: 12476.9" "Cancer enriched" "Detected in all" 27 "liver cancer: 3135.4" "Region enriched" "Detected in all" 4 "hypothalamus: 204.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "liver cancer: 195.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Macrophages, Pancreas - Beta cells, Skin - Adipocytes (Skin), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001641, CAB004555" Supported "Secreted to blood" Transport NA NA 46100000000 210000000000 "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "CAB004555: AB_670938, HPA001641: AB_1079795" "unprognostic (9.42e-3)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.60e-2)" "unprognostic (6.69e-4)" "prognostic favorable (1.74e-8)" "unprognostic (2.39e-1)" "unprognostic (5.76e-2)" "unprognostic (3.26e-2)" "unprognostic (3.26e-1)" "unprognostic (3.44e-1)" "unprognostic (7.14e-3)" "unprognostic (9.88e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (8.60e-2)" RCN1 "FLJ37041, PIG20, Rcal, RCN" ENSG00000049449 "Reticulocalbin 1" Q15293 11 32091074-32105722 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 644.5" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 273.9;Muller glia cells: 238.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038474, HPA062104" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 9400000 "Cluster 33: Non-specific - ATP binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 19 "Endoplasmic reticulum" "HPA038474: AB_10672595, HPA062104: AB_2684683" "unprognostic (1.65e-1)" "unprognostic (7.69e-3)" "unprognostic (1.24e-1)" "unprognostic (2.03e-2)" "unprognostic (7.20e-3)" "unprognostic (1.70e-2)" "unprognostic (6.92e-3)" "prognostic unfavorable (7.13e-6)" "unprognostic (8.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.12e-1)" "unprognostic (9.32e-2)" "prognostic unfavorable (2.70e-13)" "unprognostic (1.78e-2)" "unprognostic (2.04e-1)" "unprognostic (1.14e-1)" "unprognostic (6.93e-3)" RCN2 "E6BP, ERC-55, ERC55, TCBP49" ENSG00000117906 "Reticulocalbin 2" Q14257 15 76931738-76954393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 313.9" "Cell type enhanced" "Detected in all" "Spermatocytes: 511.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030694, HPA030695" Enhanced Supported Enhanced "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 92000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Spermatocytes - Spermatogenesis" 4 "Endoplasmic reticulum" "HPA030694: AB_2673573, HPA030695: AB_2673574" "unprognostic (1.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.92e-2)" "unprognostic (3.45e-2)" "unprognostic (2.42e-1)" "unprognostic (8.71e-2)" "prognostic unfavorable (7.36e-5)" "unprognostic (1.74e-1)" "unprognostic (2.20e-2)" "unprognostic (4.61e-3)" "unprognostic (1.39e-1)" "unprognostic (1.98e-1)" "unprognostic (1.70e-2)" "unprognostic (2.11e-2)" "unprognostic (2.99e-1)" "unprognostic (1.15e-1)" "unprognostic (3.67e-2)" RCN3 RLP49 ENSG00000142552 "Reticulocalbin 3" Q96D15 19 49528003-49546962 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 54.4;Fibroblasts: 110.5;Leydig cells: 38.1;Ovarian stromal cells: 45.2;Pancreatic endocrine cells: 59.4;Peritubular cells: 42.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.9" "Group enriched" "Detected in many" 9 "granulocytes: 2.6;NK-cells: 1.8;T-cells: 6.9" "Cancer enhanced" "Detected in all" "Bone cancer: 127.6;Sarcoma: 142.8" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043134, HPA050402" Uncertain Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Transport No No 1600000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 6 "Endoplasmic reticulum" Vesicles "HPA043134: AB_2678332, HPA050402: AB_2681114" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.77e-3)" "unprognostic (8.87e-2)" "unprognostic (3.36e-3)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (1.16e-1)" "unprognostic (7.47e-2)" "unprognostic (9.75e-2)" "unprognostic (2.85e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.80e-12)" "unprognostic (5.26e-2)" "unprognostic (3.90e-2)" "unprognostic (1.56e-2)" "unprognostic (4.20e-3)" RCOR1 "COREST, KIAA0071, RCOR" ENSG00000089902 "REST corepressor 1" Q9UKL0 14 102592649-102730561 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001956, HPA049327, HPA054241" Supported Enhanced Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 35: Non-specific - DNA binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Monocytes - Innate immune response" 5 Nucleoplasm "CAB001956: , HPA049327: AB_2680715, HPA054241: AB_2682426" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.17e-1)" "unprognostic (4.01e-3)" "unprognostic (1.25e-1)" "unprognostic (2.18e-1)" "unprognostic (9.96e-3)" "unprognostic (1.72e-2)" "unprognostic (1.87e-2)" "unprognostic (4.98e-2)" "unprognostic (1.46e-2)" "unprognostic (6.05e-3)" "unprognostic (7.23e-2)" "unprognostic (1.39e-1)" "unprognostic (2.02e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.72e-4)" RDH11 "ARSDR1, MDT1, SDR7C1" ENSG00000072042 "Retinol dehydrogenase 11" Q8TC12 14 67676800-67695793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Cataract, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 562.6" "Cell type enriched" "Detected in many" 6 "Prostatic glandular cells: 1470.8" "Cancer enriched" "Detected in all" 13 "prostate cancer: 286.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046011 Enhanced "Intracellular and membrane" Enzyme NA NA 340000 "Cluster 41: Basophils - Unknown function" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 27: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "CAB046011: AB_11129613" "unprognostic (1.38e-1)" "unprognostic (6.86e-3)" "unprognostic (1.77e-1)" "prognostic favorable (2.62e-4)" "unprognostic (6.06e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (9.29e-2)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.58e-2)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "prognostic favorable (1.30e-7)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (4.74e-2)" RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 216.0;skin 1: 61.8" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 292.3;Rod photoreceptor cells: 445.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 76: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" 1 "unprognostic (4.25e-3)" "unprognostic (4.50e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (2.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.69e-2)" "unprognostic (2.72e-3)" "unprognostic (7.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.42e-2)" "unprognostic (6.47e-2)" "unprognostic (7.83e-2)" "unprognostic (3.58e-1)" "unprognostic (3.92e-1)" RDH13 SDR7C3 ENSG00000160439 "Retinol dehydrogenase 13" Q8NBN7 19 55039108-55071291 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in all" 5 "Syncytiotrophoblasts: 242.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042006 Approved Supported Mitochondria,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "Mitochondria, Cytosol" "HPA042006: AB_10960270" "unprognostic (9.26e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (8.74e-2)" "unprognostic (1.08e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-1)" "unprognostic (9.42e-3)" "unprognostic (1.61e-1)" "unprognostic (2.45e-3)" "prognostic favorable (2.09e-4)" "unprognostic (2.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (1.66e-3)" RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 91.2;liver: 57.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 34.0;Proximal enterocytes: 35.7;Rod photoreceptor cells: 72.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 11: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 66: Photoreceptor cells - Visual perception" 1 Vesicles "HPA063345: AB_2684992" "unprognostic (1.04e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.05e-1)" "unprognostic (1.26e-3)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (3.46e-2)" "unprognostic (2.12e-3)" "unprognostic (3.27e-2)" REG1A "PSP, PSPS, PSPS1, PTP, REG" ENSG00000115386 "Regenerating family member 1 alpha" P05451 2 79120362-79123409 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 100880.7" "Cell type enriched" "Detected in some" 14 "Exocrine glandular cells: 77260.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 1268.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 47 "breast cancer: 94.7;colorectal cancer: 64.6;Gastric cancer: 52.0;Rhabdoid: 138.8" "Low region specificity" "Detected in single" "CAB025138, HPA045549, HPA045579" Enhanced "Secreted to digestive system" "No annotated function" NA NA 68000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" "CAB025138: , HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (1.89e-1)" "unprognostic (2.91e-2)" "unprognostic (3.39e-1)" "unprognostic (1.45e-1)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.52e-2)" "unprognostic (3.54e-3)" "unprognostic (5.53e-2)" "unprognostic (5.54e-2)" REG1B "PSPS2, REGH, REGI-BETA, REGL" ENSG00000172023 "Regenerating family member 1 beta" P48304 2 79085023-79088019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 38577.5" "Cell type enriched" "Detected in some" 7 "Exocrine glandular cells: 25526.6" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 201.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.3" "HPA045549, HPA045579" Supported "Secreted to digestive system" "No annotated function" NA NA 32000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (4.08e-1)" "unprognostic (1.09e-1)" "unprognostic (3.51e-3)" "unprognostic (9.20e-2)" REG3A "HIP, PAP, PAP1, PBCGF, REG-III, REG3" ENSG00000172016 "Regenerating family member 3 alpha" Q06141 2 79157003-79159753 "Plasma proteins, Predicted secreted proteins, Transporters" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 60 "intestine: 6550.6;pancreas: 11855.9" "Group enriched" "Detected in some" 6 "Exocrine glandular cells: 8672.0;Undifferentiated cells: 5194.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 710.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "colorectal cancer: 13.6" "HPA047894, HPA048334, HPA060705" Supported Approved Cytosol "Secreted to digestive system" "Acute phase" NA NA 23000000 "Cluster 48: Stomach - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 1 Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (2.43e-2)" "unprognostic (2.12e-1)" "unprognostic (3.62e-2)" "unprognostic (1.42e-1)" REG3G "LPPM429, PAP1B, UNQ429" ENSG00000143954 "Regenerating family member 3 gamma" Q6UW15 2 79025686-79028505 "Predicted secreted proteins" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "pancreas: 3414.4" "Group enriched" "Detected in some" 6 "Exocrine glandular cells: 149.0;Proximal enterocytes: 48.5" "Cancer enriched" "Detected in many" 13 "pancreatic cancer: 71.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047894, HPA048334, HPA060705" Uncertain Approved Cytosol "Secreted to digestive system" "Acute phase" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 69: Skin cancer - ECM organization" "Cluster 60: Pancreatic exocrine cells - Proteolysis" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (3.29e-1)" "unprognostic (2.20e-1)" "unprognostic (1.29e-1)" "unprognostic (8.82e-2)" "unprognostic (7.20e-3)" "unprognostic (5.64e-2)" REG4 "GISP, REG-IV, RELP" ENSG00000134193 "Regenerating family member 4" Q9BYZ8 1 119794017-119811580 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 644.3" "Group enriched" "Detected in some" 47 "Enteroendocrine cells: 7572.0;Intestinal goblet cells: 4357.1" "Group enriched" "Detected in many" 21 "colorectal cancer: 180.6;pancreatic cancer: 215.1;stomach cancer: 162.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive CD8 T-cell: 24.7" "Lineage enriched" "Detected in single" 100 "T-cells: 24.7" "Group enriched" "Detected in many" 4 "colorectal cancer: 119.0;Esophageal cancer: 120.2;Gastric cancer: 177.8;pancreatic cancer: 62.6" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025867, HPA046555" Enhanced "Secreted to digestive system" "No annotated function" NA NA 460000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 20: Enteroendocrine cells - Hormone signaling" "CAB025867: , HPA046555: AB_2679696" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (2.86e-3)" "unprognostic (2.57e-1)" "unprognostic (6.52e-2)" "unprognostic (6.20e-3)" "unprognostic (1.11e-1)" "unprognostic (1.64e-2)" "unprognostic (7.10e-2)" "unprognostic (7.85e-2)" "unprognostic (2.99e-1)" "unprognostic (5.12e-3)" "unprognostic (8.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-3)" RELN "PRO1598, RL" ENSG00000189056 Reelin P78509 7 103471381-103989658 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein, Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 68.5" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 356.4;Lymphatic endothelial cells: 168.9;Schwann cells: 88.0" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Region enriched" "Detected in all" 8 "cerebellum: 141.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 21.7;liver cancer: 12.5;Myeloma: 11.2" "Pancreas - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 148.3" HPA077891 Approved "Golgi apparatus,Vesicles" "Secreted in brain" "Developmental protein" NA NA 30000000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" Vesicles "HPA077891: " "unprognostic (1.42e-1)" "unprognostic (2.93e-3)" "unprognostic (4.31e-2)" "unprognostic (1.29e-4)" "unprognostic (1.30e-1)" "unprognostic (6.95e-2)" "unprognostic (1.85e-1)" "unprognostic (8.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.48e-2)" "unprognostic (3.31e-3)" "unprognostic (3.86e-1)" "unprognostic (2.02e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.06e-2)" REN ENSG00000143839 Renin P00797 1 204154819-204190324 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "kidney: 157.7" "Group enriched" "Detected in some" 5 "Club cells: 33.8;Late spermatids: 27.8;Smooth muscle cells: 14.8" "Cancer enriched" "Detected in many" 8 "renal cancer: 39.4" "Region enhanced" "Detected in many" "choroid plexus: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bladder cancer: 22.1;colorectal cancer: 8.4" "Lung - Alveolar cells type 2, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA005131 Approved "Secreted to blood" Enzyme NA NA 692000 10000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Connective tissue cells - ECM organization" 2 "HPA005131: AB_1079174" "unprognostic (4.45e-2)" "unprognostic (3.35e-1)" "unprognostic (1.62e-1)" "unprognostic (8.58e-2)" "unprognostic (2.89e-1)" "unprognostic (1.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (7.20e-3)" "unprognostic (1.37e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (1.22e-1)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (6.49e-2)" REPS2 POB1 ENSG00000169891 "RALBP1 associated Eps domain containing 2" Q8NFH8 X 16946658-17153272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 114.0;Inhibitory neurons: 136.5;Oligodendrocyte precursor cells: 79.7;Oligodendrocytes: 189.9" "Cancer enhanced" "Detected in all" "prostate cancer: 13.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "basophil: 5.8;eosinophil: 4.5;neutrophil: 14.3" "Lineage enriched" "Detected in single" 28 "granulocytes: 14.3" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000565, HPA026073" Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 3: Basal prostatic cells - Lipid metabolism" 5 "HPA000565: AB_1079800, HPA026073: AB_1856176" "unprognostic (6.58e-2)" "unprognostic (2.14e-1)" "unprognostic (3.35e-2)" "unprognostic (7.83e-2)" "unprognostic (4.23e-2)" "unprognostic (3.70e-3)" "prognostic favorable (5.36e-4)" "unprognostic (4.85e-2)" "unprognostic (2.87e-2)" "unprognostic (5.53e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (1.83e-1)" "prognostic favorable (4.08e-4)" "unprognostic (5.89e-2)" "unprognostic (1.03e-1)" "unprognostic (2.43e-2)" "prognostic favorable (4.56e-4)" RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 244.0" "Group enriched" "Detected in some" 9 "Hofbauer cells: 172.4;Kupffer cells: 48.2;Macrophages: 70.5;monocytes: 79.4" "Group enriched" "Detected in many" 4 "lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 8 "classical monocyte: 171.1;intermediate monocyte: 92.0;myeloid DC: 118.9;non-classical monocyte: 47.6" "Group enriched" "Detected in many" 11 "dendritic cells: 118.9;monocytes: 171.1" "Cancer enriched" "Detected in single" 186 "Leukemia: 67.0" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Liver - Neutrophils, Prostate - Macrophages, Thyroid - Neutrophils" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" Hormone NA NA 5120000 1200000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 6: Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 1 "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" RETNLB "FIZZ2, HXCP2, RELMb" ENSG00000163515 "Resistin like beta" Q9BQ08 3 108743424-108757410 "Predicted secreted proteins, Transporters" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "intestine: 223.6" "Cell type enriched" "Detected in some" 19 "Intestinal goblet cells: 206.0" "Cancer enriched" "Detected in some" 10 "colorectal cancer: 16.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA049152 Enhanced Uncertain "Endoplasmic reticulum" "Secreted to blood" Hormone NA NA 123000 "Cluster 45: Intestine - Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" "Endoplasmic reticulum" "HPA049152: AB_2680655" "prognostic favorable (6.86e-5)" "unprognostic (1.19e-3)" "unprognostic (3.37e-2)" "unprognostic (4.69e-2)" "unprognostic (2.67e-2)" "unprognostic (5.78e-2)" "unprognostic (4.26e-1)" RGCC "bA157L14.2, C13orf15, RGC-32, RGC32" ENSG00000102760 "Regulator of cell cycle" Q9H4X1 13 41457550-41470871 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 409.9;lung: 673.8" "Cell type enhanced" "Detected in many" "Adipocytes: 1212.9;Langerhans cells: 597.4;Schwann cells: 752.9;T-cells: 544.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 160.9;T-reg: 91.1" "Lineage enriched" "Detected in many" 15 "T-cells: 160.9" "Cancer enhanced" "Detected in many" "lymphoma: 34.0" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035638, HPA063701" Enhanced Supported Nucleoplasm,Nucleoli "Intracellular and membrane" Other No No 910000 "Cluster 31: T-cells - T-cell receptor" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Nucleoplasm Nucleoli "HPA035638: AB_10670152, HPA063701: AB_2685096" "unprognostic (1.39e-3)" "unprognostic (4.61e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (2.28e-1)" "unprognostic (4.27e-2)" "unprognostic (2.85e-1)" "unprognostic (1.49e-3)" "unprognostic (1.49e-2)" "unprognostic (3.99e-2)" "unprognostic (1.57e-3)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.04e-3)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.42e-3)" RGL4 Rgr ENSG00000159496 "Ral guanine nucleotide dissociation stimulator like 4" Q8IZJ4 22 23688136-23699176 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "bone marrow: 156.9" "Group enriched" "Detected in some" 7 "Early spermatids: 26.3;monocytes: 44.4;NK-cells: 34.5;T-cells: 47.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 394.7;neutrophil: 519.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 519.0" "Cancer enhanced" "Detected in many" "Leukemia: 12.6" "Lung - Neutrophil_2, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids" HPA035979 Uncertain Approved Centrosome "Intracellular and membrane" Other NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" Centrosome "HPA035979: AB_10673227" "unprognostic (1.48e-4)" "unprognostic (2.75e-4)" "unprognostic (4.44e-2)" "unprognostic (1.11e-4)" "unprognostic (3.10e-1)" "unprognostic (2.93e-4)" "unprognostic (4.92e-2)" "unprognostic (2.06e-2)" "unprognostic (2.78e-1)" "unprognostic (3.11e-1)" "unprognostic (4.25e-2)" "unprognostic (3.80e-2)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (5.13e-2)" "unprognostic (1.26e-1)" "unprognostic (1.07e-3)" RGMA RGM ENSG00000182175 "Repulsive guidance molecule BMP co-receptor a" Q96B86 15 93035271-93089211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 192.0" "Cell type enhanced" "Detected in many" "Astrocytes: 135.9;Basal squamous epithelial cells: 44.1;Leydig cells: 115.8;Peritubular cells: 113.1;Skeletal myocytes: 50.7;Spermatogonia: 45.4;Squamous epithelial cells: 58.6" "Cancer enriched" "Detected in many" 6 "glioma: 26.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.3;Sarcoma: 10.4" "Kidney - Fibroblasts, Lung - Fibroblast_2, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012343, HPA039880, HPA044222" Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" "No annotated function" NA NA 2000000 "Cluster 79: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 53: Fibroblasts - ECM organization" 1 Nucleoplasm Cytosol "CAB012343: AB_777667, HPA039880: AB_2676723, HPA044222: AB_2678861" "unprognostic (3.21e-2)" "unprognostic (1.59e-1)" "unprognostic (8.85e-2)" "unprognostic (3.96e-3)" "unprognostic (5.73e-2)" "unprognostic (4.72e-3)" "unprognostic (2.53e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.11e-1)" "unprognostic (6.25e-2)" "unprognostic (3.59e-4)" "unprognostic (8.11e-2)" "unprognostic (2.92e-2)" "unprognostic (1.73e-1)" "unprognostic (7.98e-5)" RIC3 "AYST720, FLJ11608, PRO1385" ENSG00000166405 "RIC3 acetylcholine receptor chaperone" Q7Z5B4 11 8106056-8169055 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 162.8;Horizontal cells: 130.9;Rod photoreceptor cells: 213.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 12.8;granulocytes: 3.7;T-cells: 6.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.6;prostate cancer: 4.0;testis cancer: 4.0" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065016 Approved "Intracellular and membrane" Other NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 55: Non-specific - Transcription" "HPA065016: AB_2685404" "unprognostic (2.51e-3)" "unprognostic (2.32e-1)" "unprognostic (1.21e-1)" "unprognostic (6.98e-4)" "unprognostic (3.22e-2)" "unprognostic (1.04e-2)" "unprognostic (1.29e-1)" "unprognostic (2.43e-2)" "unprognostic (1.59e-2)" "unprognostic (1.48e-2)" "unprognostic (4.45e-4)" "unprognostic (1.28e-1)" "unprognostic (2.23e-9)" "unprognostic (4.37e-2)" "unprognostic (5.53e-2)" "unprognostic (1.35e-1)" "unprognostic (2.52e-2)" RIPPLY1 ENSG00000147223 "Ripply transcriptional repressor 1" Q0D2K3 X 106900063-106903341 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 3.3;liver: 5.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 5.1" "Cancer enhanced" "Detected in some" "liver cancer: 2.2;renal cancer: 3.6" "Region enhanced" "Detected in single" "choroid plexus: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052284 Uncertain "Intracellular and membrane" "Developmental protein" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 43: Hepatocytes - Metabolism" 28 "HPA052284: AB_2681785" "unprognostic (1.48e-1)" "unprognostic (4.35e-2)" "unprognostic (1.67e-1)" "unprognostic (9.52e-3)" "unprognostic (7.00e-3)" "unprognostic (1.13e-2)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (2.42e-1)" "unprognostic (5.37e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-3)" "unprognostic (1.97e-1)" "unprognostic (1.97e-1)" "unprognostic (1.97e-3)" "unprognostic (1.31e-1)" RLN1 H1 ENSG00000107018 "Relaxin 1" P04808 9 5334930-5339876 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 71 "prostate: 22.7" "Cell type enriched" "Detected in some" 10 "Prostatic glandular cells: 45.8" "Cancer enriched" "Detected in some" 106 "prostate cancer: 67.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 59 "prostate cancer: 6.5" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Secreted to blood" Hormone NA NA "Cluster 64: Neuronal - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "unprognostic (7.12e-6)" "unprognostic (2.32e-1)" "unprognostic (7.29e-2)" "unprognostic (1.98e-1)" "unprognostic (2.22e-2)" "unprognostic (1.04e-1)" "unprognostic (4.32e-2)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (4.08e-4)" "unprognostic (8.15e-2)" "unprognostic (2.89e-4)" "unprognostic (8.82e-3)" "unprognostic (3.23e-2)" "unprognostic (3.23e-2)" "unprognostic (1.53e-2)" RLN2 "bA12D24.1.1, bA12D24.1.2, H2, RLXH2" ENSG00000107014 "Relaxin 2" P04090 9 5299864-5304716 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.0" "Cell type enhanced" "Detected in many" "Early spermatids: 16.0;Oocytes: 48.5;Spermatocytes: 14.6;Syncytiotrophoblasts: 12.2" "Group enriched" "Detected in some" 5 "breast cancer: 2.0;prostate cancer: 6.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 26 "gdT-cell: 1.4;MAIT T-cell: 4.2;memory B-cell: 1.9;memory CD4 T-cell: 2.8;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.0;naive CD8 T-cell: 3.0;NK-cell: 3.5;T-reg: 1.4" "Group enriched" "Detected in many" 33 "B-cells: 1.9;NK-cells: 3.5;T-cells: 4.2" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Secreted to blood" Hormone NA NA 24400 10000 "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "unprognostic (1.63e-3)" "unprognostic (1.26e-1)" "unprognostic (2.09e-3)" "unprognostic (2.84e-1)" "unprognostic (2.03e-2)" "unprognostic (9.99e-2)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (2.50e-3)" "unprognostic (9.18e-2)" "unprognostic (1.74e-6)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (1.88e-2)" "unprognostic (8.41e-4)" RLN3 "H3, RXN3, ZINS4" ENSG00000171136 "Relaxin 3" Q8WXF3 19 14028148-14031551 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "parathyroid gland: 1.6;testis: 1.0" "Cell type enhanced" "Detected in some" "Early spermatids: 2.7;Kupffer cells: 3.8;Late spermatids: 8.2;Macrophages: 1.5;monocytes: 1.7;Spermatogonia: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "midbrain: 11.7;pons and medulla: 27.2" "Region enriched" "Detected in many" 9 "pons: 31.2" "Secreted to blood" Hormone NA NA 60000000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 47: Leukemia - Hemostasis" "Cluster 36: Late spermatids - Unknown function" "unprognostic (1.96e-2)" "unprognostic (2.54e-2)" "unprognostic (3.94e-1)" RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 8831.6" "Cell type enhanced" "Detected in many" "Adipocytes: 775.0;Alveolar cells type 1: 1360.4;Alveolar cells type 2: 1066.1;Gastric mucus-secreting cells: 767.6;Hofbauer cells: 1650.7;Macrophages: 1284.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 78.8;pancreatic cancer: 57.9;skin cancer: 60.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Pancreas - Exocrine glandular cells, Skeletal muscle - Macrophages, Testis - Sertoli cells, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" Enzyme NA NA 1100000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Macrophages - Innate immune response" 2 Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" RNASE10 "RAH1, RNASE9" ENSG00000182545 "Ribonuclease A family member 10 (inactive)" Q5GAN6 14 20505537-20513884 "Predicted secreted proteins" "Cell adhesion, Fertilization" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "head and neck cancer: 2.0;testis cancer: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 3.4;head and neck cancer: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052593 Uncertain "Secreted - unknown location" "Cell adhesion" NA NA "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" 6 "HPA052593: AB_2681878" "unprognostic (2.48e-3)" "unprognostic (2.22e-1)" "unprognostic (2.46e-2)" "unprognostic (1.17e-1)" "unprognostic (1.74e-1)" "unprognostic (5.91e-3)" "unprognostic (5.03e-3)" "unprognostic (5.58e-3)" "unprognostic (4.20e-2)" "unprognostic (3.04e-1)" "unprognostic (1.98e-3)" "unprognostic (1.11e-1)" "unprognostic (7.88e-4)" "unprognostic (1.58e-1)" "unprognostic (3.62e-1)" "unprognostic (8.76e-2)" "unprognostic (2.58e-1)" RNASE11 "C14orf6, RAJ1" ENSG00000173464 "Ribonuclease A family member 11 (inactive)" Q8TAA1 14 20582892-20609884 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "epididymis: 643.4" "Group enriched" "Detected in some" 94 "Early spermatids: 22.9;Late spermatids: 52.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA003724 Uncertain "Secreted in male reproductive system" Enzyme NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 11: Late spermatids - Unknown function" "HPA003724: AB_1079817" RNASE12 RAI1 ENSG00000258436 "Ribonuclease A family member 12 (inactive)" Q5GAN4 14 20590073-20591376 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 288 "epididymis: 679.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044175, HPA059465" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "HPA044175: AB_10960390, HPA059465: AB_2732638" RNASE13 RAL1 ENSG00000206150 "Ribonuclease A family member 13 (inactive)" Q5GAN3 14 21032818-21034807 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "epididymis: 299.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "unprognostic (2.54e-1)" "unprognostic (2.52e-1)" "unprognostic (2.86e-1)" "unprognostic (8.40e-2)" "unprognostic (1.93e-1)" "unprognostic (7.15e-2)" "unprognostic (1.63e-3)" "unprognostic (5.20e-4)" "unprognostic (1.47e-2)" RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1689.0" "Group enriched" "Detected in some" 4 "Kupffer cells: 220.6;Macrophages: 68.7" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 459.4;eosinophil: 1355.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 1355.1" "Cancer enriched" "Detected in single" 210 "Leukemia: 160.0" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Prostate - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" HPA044983 Enhanced "Secreted to blood" Enzyme NA NA 200000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 6: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" RNASE3 "ECP, RAF1, RNS3" ENSG00000169397 "Ribonuclease A family member 3" P12724 14 20891385-20892348 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 93 "bone marrow: 896.5" "Cell type enhanced" "Detected in some" "Early spermatids: 21.7;Erythroid cells: 5.2;Kupffer cells: 7.3;Late spermatids: 12.3;Rod photoreceptor cells: 3.8" "Cancer enriched" "Detected in single" 8 "glioma: 2.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 20 "eosinophil: 307.0" "Lineage enriched" "Detected in many" 20 "granulocytes: 307.0" "Cancer enriched" "Detected in single" 42 "Leukemia: 22.3" "Lung - Neutrophil_1, Testis - Late spermatids" HPA056183 Enhanced "Secreted to blood" Enzyme NA NA 4200000 "Cluster 29: Non-specific - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 18: Early spermatids - Unknown function" "HPA056183: AB_2683059" "unprognostic (2.54e-2)" "unprognostic (6.61e-2)" "unprognostic (1.84e-1)" "unprognostic (2.50e-1)" "unprognostic (1.37e-2)" "unprognostic (8.21e-2)" "unprognostic (6.45e-2)" "unprognostic (9.20e-3)" "unprognostic (1.20e-1)" "unprognostic (9.21e-2)" "unprognostic (8.62e-7)" "unprognostic (6.29e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (2.37e-1)" RNASE4 RAB1 ENSG00000258818 "Ribonuclease A family member 4" P34096 14 20684560-20701216 "Plasma proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 463.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 56.1;Gastric mucus-secreting cells: 48.9;Hepatocytes: 47.7;Intestinal goblet cells: 97.9;Proximal enterocytes: 38.9" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 61000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-2)" "unprognostic (3.18e-4)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "prognostic favorable (9.62e-5)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (9.16e-2)" "unprognostic (4.27e-2)" RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 107.8" "Group enriched" "Detected in many" 5 "B-cells: 132.1;dendritic cells: 422.0;Hofbauer cells: 260.5;Kupffer cells: 438.5;Langerhans cells: 223.1;Macrophages: 253.9;Schwann cells: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1241.7" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 21.5;lymphoma: 7.2;Myeloma: 9.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" Enzyme NA NA 2600000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" RNASE7 RAE1 ENSG00000165799 "Ribonuclease A family member 7" Q9H1E1 14 21042316-21044234 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 72.5;lymphoid tissue: 23.4;skin 1: 27.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.7;Cholangiocytes: 9.5;Ductal cells: 5.0;Salivary duct cells: 2.4;Suprabasal keratinocytes: 2.6;Syncytiotrophoblasts: 13.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.3;head and neck cancer: 10.2" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular)" "HPA005690, CAB062560, CAB068225" Enhanced "Secreted in other tissues" Enzyme NA NA 280000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "CAB062560: AB_2665595, CAB068225: AB_2665594, HPA005690: AB_1079819" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (8.27e-2)" "unprognostic (7.80e-2)" "unprognostic (8.73e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.17e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "unprognostic (3.24e-1)" "unprognostic (3.42e-1)" RNASE8 RAE2 ENSG00000173431 "Ribonuclease A family member 8" Q8TDE3 14 21057822-21058455 "Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 229 "salivary gland: 53.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to digestive system" Enzyme NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 75: Serous glandular cells - Salivary secretion" RNASE9 "h461, RAK1" ENSG00000188655 "Ribonuclease A family member 9 (inactive)" P60153 14 20556093-20560931 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 962 "epididymis: 96.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Myeloid leukemia - Innate immune response" RNASEH1 ENSG00000171865 "Ribonuclease H1" O60930 2 3541430-3558333 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034817, HPA043037" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 45: Non-specific - Mixed function" 5 "Nucleoplasm, Cytosol" "HPA034817: , HPA043037: AB_2678280" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "unprognostic (8.81e-3)" "unprognostic (4.32e-3)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.83e-6)" "unprognostic (9.43e-2)" "unprognostic (8.46e-3)" "unprognostic (6.38e-2)" "unprognostic (2.29e-3)" "unprognostic (2.67e-1)" "unprognostic (4.06e-2)" "unprognostic (2.34e-2)" "unprognostic (2.11e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-3)" RNASET2 "bA514O12.3, FLJ10907, RNASE6PL" ENSG00000026297 "Ribonuclease T2" O00584 6 166922113-166957191 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Endonuclease, Hydrolase, Lyase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 768.3;Glandular and luminal cells: 777.5;Hofbauer cells: 485.7;Kupffer cells: 434.5;monocytes: 589.7;Secretory cells: 458.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 182.0" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029013, HPA066509" Approved "Secreted to blood" Immunity NA NA 15000000 "Cluster 25: Non-specific - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA029013: AB_10602922, HPA066509: AB_2685682" "unprognostic (4.18e-2)" "unprognostic (2.57e-1)" "unprognostic (1.44e-1)" "unprognostic (1.06e-1)" "unprognostic (4.13e-2)" "unprognostic (9.33e-2)" "unprognostic (1.76e-2)" "unprognostic (1.30e-1)" "unprognostic (1.15e-2)" "unprognostic (8.11e-2)" "unprognostic (1.79e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (1.70e-14)" "unprognostic (5.03e-2)" "unprognostic (7.34e-2)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" RNF150 KIAA1214 ENSG00000170153 "Ring finger protein 150" Q9ULK6 4 140859807-141212877 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 98.4;Cone photoreceptor cells: 93.5;Excitatory neurons: 178.3;Inhibitory neurons: 166.7;Microglial cells: 109.1;Oligodendrocyte precursor cells: 267.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 26.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Liver - Hepatic stellate cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037987 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "HPA037987: AB_10669512" "prognostic favorable (1.41e-4)" "unprognostic (1.95e-2)" "unprognostic (8.26e-3)" "unprognostic (2.41e-2)" "unprognostic (3.31e-1)" "unprognostic (5.38e-2)" "unprognostic (2.38e-2)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" "unprognostic (9.32e-2)" "unprognostic (3.10e-3)" "unprognostic (3.07e-1)" "unprognostic (4.02e-2)" "unprognostic (3.88e-3)" "unprognostic (9.68e-2)" "unprognostic (1.32e-3)" "unprognostic (2.41e-2)" RNF220 "C1orf164, FLJ10597" ENSG00000187147 "Ring finger protein 220" Q5VTB9 1 44405194-44651724 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cardiomyopathy, Deafness, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 88.6;skeletal muscle: 23.5" "Cell type enriched" "Detected in all" 6 "Oligodendrocytes: 1988.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027577, HPA027578" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 51: Oligodendrocytes - Unknown function" 1 Nucleoplasm Cytosol "HPA027577: AB_2672339, HPA027578: AB_10601482" "unprognostic (3.12e-2)" "unprognostic (1.24e-1)" "unprognostic (3.49e-2)" "unprognostic (2.56e-1)" "unprognostic (2.94e-2)" "unprognostic (6.96e-3)" "prognostic unfavorable (2.35e-6)" "unprognostic (1.55e-1)" "unprognostic (8.47e-2)" "unprognostic (2.13e-1)" "unprognostic (2.14e-3)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.51e-2)" "unprognostic (1.98e-1)" "unprognostic (1.37e-3)" "unprognostic (6.46e-2)" RNLS "C10orf59, FLJ11218, renalase" ENSG00000184719 "Renalase, FAD dependent amine oxidase" Q5VYX0 10 88273864-88584530 "Enzymes, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 99.5;Inhibitory neurons: 96.8;Oligodendrocyte precursor cells: 48.6;Oligodendrocytes: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 10500000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 69: Neurons - Neuronal signaling" 1 "unprognostic (3.27e-2)" "unprognostic (9.16e-2)" "unprognostic (1.27e-1)" "unprognostic (2.58e-1)" "unprognostic (1.46e-3)" "unprognostic (1.99e-1)" "unprognostic (2.01e-1)" "unprognostic (2.29e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (3.98e-1)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (7.74e-3)" "unprognostic (1.37e-2)" "unprognostic (9.80e-2)" "unprognostic (1.71e-1)" RNPEP APB ENSG00000176393 "Arginyl aminopeptidase" Q9H4A4 1 201982372-202006147 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 196.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 19.8;granulocytes: 23.2;monocytes: 30.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036074, HPA036075, HPA061487" Approved Approved "Golgi apparatus" "Secreted - unknown location" Enzyme NA NA 7800000 "Cluster 25: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus" "HPA036074: AB_2674926, HPA036075: AB_10672999, HPA061487: AB_2684537" "unprognostic (8.57e-2)" "unprognostic (3.43e-2)" "unprognostic (2.81e-1)" "unprognostic (5.45e-2)" "unprognostic (2.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.95e-2)" "unprognostic (2.87e-2)" "unprognostic (1.93e-3)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (3.50e-3)" "unprognostic (1.91e-1)" "unprognostic (6.00e-2)" "unprognostic (1.97e-2)" "unprognostic (1.68e-1)" ROR1 NTRKR1 ENSG00000185483 "Receptor tyrosine kinase like orphan receptor 1" Q01973 1 63774017-64181498 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 23.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 107.6;Astrocytes: 76.8;Inhibitory neurons: 67.4;Oligodendrocytes: 102.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" Receptor NA NA 7700000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 8: Neurons - Neuronal signaling" 2 "unprognostic (5.15e-2)" "unprognostic (1.19e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-2)" "unprognostic (6.24e-2)" "unprognostic (1.61e-1)" "unprognostic (7.11e-3)" "unprognostic (1.41e-1)" "unprognostic (4.06e-1)" "unprognostic (3.84e-1)" "unprognostic (3.20e-2)" "unprognostic (2.02e-2)" "unprognostic (3.64e-3)" "unprognostic (1.48e-2)" "unprognostic (1.52e-1)" "unprognostic (5.87e-2)" "unprognostic (5.15e-2)" RPLP2 "D11S2243E, LP2, MGC71408, P2, RPP2" ENSG00000177600 "Ribosomal protein lateral stalk subunit P2" P05387 11 809965-812880 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053635, HPA075365" Approved Approved "Nuclear speckles,Mitotic spindle,Cytosol" "Intracellular and membrane" Other Yes NA 2900000 "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 1 "Nuclear speckles, Cytosol" "Mitotic spindle" "HPA053635: AB_2682212, HPA075365: " "unprognostic (6.98e-3)" "unprognostic (2.21e-1)" "unprognostic (4.57e-2)" "unprognostic (8.63e-2)" "unprognostic (2.30e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (1.63e-1)" "unprognostic (2.98e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (6.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.16e-1)" "unprognostic (3.31e-2)" RPTN FLJ39117 ENSG00000215853 Repetin Q6XPR3 1 152153595-152159228 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 50.8;skin 1: 28.9" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 15.5" "Cancer enriched" "Detected in some" 4 "head and neck cancer: 6.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.8;colorectal cancer: 1.3;head and neck cancer: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030483, HPA030485" Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA030483: AB_2673495, HPA030485: AB_10601159" "unprognostic (1.37e-2)" "unprognostic (5.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.54e-2)" "unprognostic (4.00e-2)" "unprognostic (5.23e-3)" RS1 "RS, XLRS1" ENSG00000102104 "Retinoschisin 1" O15537 X 18639688-18672108 "Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 207 "retina: 207.2" "Group enriched" "Detected in some" 10 "Cone photoreceptor cells: 436.7;Rod photoreceptor cells: 145.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059546 Enhanced "Secreted in other tissues" "Cell adhesion" NA NA "Cluster 76: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA059546: AB_2684058" "unprognostic (8.31e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (2.39e-2)" "unprognostic (1.86e-1)" "unprognostic (4.80e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-2)" "unprognostic (1.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.77e-3)" "unprognostic (4.14e-1)" "unprognostic (7.03e-2)" "unprognostic (1.06e-1)" "unprognostic (3.06e-2)" "unprognostic (5.12e-2)" "unprognostic (2.04e-4)" RSF1 "HBXAP, p325, RSF-1, XAP8" ENSG00000048649 "Remodeling and spacing factor 1" Q96T23 11 77660009-77820869 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022626, HPA046129, HPA057547, HPA064567" Supported Enhanced Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 2 Nucleoplasm "CAB022626: , HPA046129: AB_2679550, HPA057547: AB_2683462, HPA064567: AB_2685289" "unprognostic (2.67e-1)" "unprognostic (2.02e-1)" "unprognostic (2.39e-1)" "unprognostic (4.35e-3)" "unprognostic (5.00e-3)" "unprognostic (5.57e-2)" "unprognostic (1.23e-2)" "unprognostic (2.46e-1)" "unprognostic (7.33e-3)" "unprognostic (2.35e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (6.19e-2)" "prognostic favorable (5.94e-4)" "unprognostic (1.71e-1)" "unprognostic (2.22e-1)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" RSPO1 "FLJ40906, RSPONDIN" ENSG00000169218 "R-spondin 1" Q2MKA7 1 37611350-37634892 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 27.9;endometrium 1: 40.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 12.0;Breast myoepithelial cells: 17.8;Fibroblasts: 6.0;Mesothelial cells: 33.1;Secretory cells: 24.2" "Cancer enriched" "Detected in some" 13 "ovarian cancer: 11.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA046154, HPA062923" Uncertain Approved Vesicles "Secreted in female reproductive system" Other NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 2 Vesicles "HPA046154: AB_10964912, HPA062923: " "unprognostic (1.50e-2)" "unprognostic (1.97e-3)" "unprognostic (5.99e-3)" "unprognostic (2.22e-1)" "unprognostic (1.76e-1)" "unprognostic (3.75e-6)" "unprognostic (1.84e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (2.08e-1)" "unprognostic (1.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.76e-2)" "unprognostic (3.21e-1)" "unprognostic (1.53e-2)" RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.2;intestine: 13.4;placenta: 17.0" "Group enriched" "Detected in some" 21 "Excitatory neurons: 72.9;Inhibitory neurons: 83.4;Oocytes: 152.9" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "midbrain: 51.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 6.4" "Liver - Hepatic stellate cells, Lung - Fibroblast_1, Testis - Spermatogonia" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 15.8;cerebral cortex: 14.5;hippocampal formation: 15.9;midbrain: 23.9;spinal cord: 14.5" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" "Developmental protein" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 4 "CAB025900: , HPA024764: AB_10603236, HPA053068: AB_2682031" "unprognostic (1.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.19e-1)" "unprognostic (8.33e-3)" "unprognostic (1.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" RSPO3 "FLJ14440, THSD2" ENSG00000146374 "R-spondin 3" Q9BXY4 6 127118671-127199481 "Cancer-related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 49.7" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 19.9;Endothelial cells: 17.9;Fibroblasts: 50.1;Inhibitory neurons: 16.9;Leydig cells: 27.3;Smooth muscle cells: 32.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 7.4;Rhabdoid: 20.2" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 26.0" HPA029957 Uncertain "Secreted to blood" Other NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 50: Connective tissue cells - ECM organization" "HPA029957: AB_10602087" "unprognostic (4.77e-2)" "unprognostic (3.95e-2)" "unprognostic (1.27e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-1)" "unprognostic (2.99e-1)" "unprognostic (9.71e-2)" "unprognostic (1.49e-2)" "unprognostic (3.77e-2)" "unprognostic (3.21e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-1)" "unprognostic (1.07e-3)" "unprognostic (7.94e-2)" "unprognostic (2.76e-1)" "unprognostic (1.64e-2)" "unprognostic (7.89e-3)" RSPO4 "C20orf182, dJ824F16.3" ENSG00000101282 "R-spondin 4" Q2I0M5 20 958452-1002311 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.8;lung: 12.2" "Cell type enhanced" "Detected in some" "Astrocytes: 10.2;Early spermatids: 5.0;Late spermatids: 7.5;Oligodendrocyte precursor cells: 8.0;Oligodendrocytes: 6.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.8" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" HPA048887 Uncertain "Secreted in other tissues" Other NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 11 "HPA048887: AB_2680545" "unprognostic (2.36e-1)" "unprognostic (3.60e-3)" "unprognostic (2.88e-2)" "prognostic unfavorable (2.98e-6)" "unprognostic (8.93e-2)" "unprognostic (1.14e-3)" "unprognostic (1.05e-2)" "unprognostic (1.47e-1)" "unprognostic (6.50e-2)" "unprognostic (2.02e-2)" "unprognostic (5.26e-3)" "unprognostic (2.96e-1)" "unprognostic (5.68e-9)" "unprognostic (6.65e-3)" "unprognostic (4.41e-2)" "unprognostic (6.18e-3)" "unprognostic (2.22e-2)" RSPRY1 KIAA1972 ENSG00000159579 "Ring finger and SPRY domain containing 1" Q96DX4 16 57186137-57240469 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003729 Approved "Secreted to blood" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 21: Early spermatids - Spermatogenesis" "HPA003729: AB_10964215" "unprognostic (2.73e-2)" "unprognostic (7.10e-2)" "unprognostic (1.32e-3)" "unprognostic (5.32e-2)" "unprognostic (1.63e-3)" "prognostic unfavorable (8.21e-5)" "unprognostic (6.84e-2)" "unprognostic (1.36e-1)" "unprognostic (4.63e-2)" "unprognostic (1.29e-1)" "unprognostic (2.26e-2)" "unprognostic (1.01e-1)" "unprognostic (4.89e-2)" "unprognostic (4.68e-2)" "unprognostic (3.35e-1)" "unprognostic (6.47e-2)" "unprognostic (4.81e-3)" RTBDN FLJ36353 ENSG00000132026 Retbindin Q9BSG5 19 12825478-12835428 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 279.1" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 934.5;Rod photoreceptor cells: 445.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA052511 Approved "Endoplasmic reticulum" "Secreted in other tissues" "No annotated function" NA NA "Cluster 76: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 66: Photoreceptor cells - Visual perception" "Endoplasmic reticulum" "HPA052511: AB_2797243" "unprognostic (4.55e-4)" "unprognostic (3.94e-3)" "unprognostic (2.18e-1)" "unprognostic (1.54e-4)" "unprognostic (3.33e-2)" "unprognostic (2.18e-1)" "unprognostic (1.08e-2)" "unprognostic (2.45e-2)" "unprognostic (2.02e-2)" "unprognostic (3.55e-1)" "unprognostic (6.48e-2)" "unprognostic (7.04e-3)" "unprognostic (7.66e-9)" "unprognostic (3.55e-2)" "unprognostic (1.00e-1)" "unprognostic (7.05e-2)" "unprognostic (2.24e-2)" RTF1 KIAA0252 ENSG00000137815 "RTF1 homolog, Paf1/RNA polymerase II complex component" Q92541 15 41408408-41483563 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006714, CAB079946, CAB079947" Supported Approved Nucleoplasm,Cytosol "Intracellular and membrane" Transcription NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" 2 Nucleoplasm Cytosol "CAB079946: , CAB079947: , HPA006714: AB_1079855" "unprognostic (1.10e-1)" "unprognostic (5.03e-2)" "unprognostic (1.40e-1)" "unprognostic (1.86e-2)" "unprognostic (1.21e-2)" "unprognostic (1.88e-1)" "unprognostic (8.87e-2)" "unprognostic (5.36e-2)" "unprognostic (4.21e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.19e-1)" "unprognostic (1.69e-2)" "unprognostic (8.22e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (9.50e-2)" RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.3;Cone photoreceptor cells: 27.2;Excitatory neurons: 42.1;Horizontal cells: 18.9;Inhibitory neurons: 17.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 8.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Receptor Yes NA 35000 "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 5 "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: AB_10963229" "unprognostic (5.23e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (7.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "unprognostic (6.21e-2)" "unprognostic (2.55e-3)" "unprognostic (6.32e-3)" "prognostic unfavorable (7.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (3.15e-2)" RTN4RL2 "NgR2, NGRH1" ENSG00000186907 "Reticulon 4 receptor like 2" Q86UN3 11 57460528-57477534 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 35.2;liver: 39.7;thyroid gland: 29.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.4;Excitatory neurons: 16.1;Hepatocytes: 11.9;Oligodendrocyte precursor cells: 9.0" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 10 "amygdala: 72.3;basal ganglia: 61.2;cerebral cortex: 116.1;hippocampal formation: 86.0;white matter: 49.6" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "amygdala: 25.0;cerebral cortex: 45.0;hippocampal formation: 38.9" "Intracellular and membrane" Receptor NA NA 27000000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (6.27e-3)" "unprognostic (2.02e-2)" "unprognostic (4.57e-2)" "unprognostic (8.40e-2)" "unprognostic (8.51e-2)" "unprognostic (7.64e-2)" "unprognostic (6.83e-2)" "unprognostic (3.72e-2)" "unprognostic (7.27e-2)" "unprognostic (2.41e-1)" "unprognostic (1.09e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (3.05e-7)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" "unprognostic (5.16e-3)" "unprognostic (2.18e-2)" S100A12 "CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6" ENSG00000163221 "S100 calcium binding protein A12" P80511 1 153373711-153375621 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3451.3" "Group enriched" "Detected in many" 9 "Hofbauer cells: 388.2;Kupffer cells: 667.6;Macrophages: 386.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 51.4" "Region enhanced" "Detected in many" "cerebral cortex: 7.2" "Group enriched" "Detected in many" 13 "classical monocyte: 1326.0;neutrophil: 1795.5" "Group enriched" "Detected in many" 13 "granulocytes: 1795.5;monocytes: 1326.0" "Group enriched" "Detected in some" 5 "cervical cancer: 3.9;head and neck cancer: 5.5;Leukemia: 2.0" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Region enhanced" "Detected in some" "cerebral cortex: 5.5" "HPA002881, CAB025872" Enhanced "Secreted to blood" Immunity NA NA 28500000 8300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 6: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Neutrophils - Degranulation" "CAB025872: , HPA002881: AB_1848175" "unprognostic (1.33e-1)" "unprognostic (4.51e-2)" "unprognostic (7.49e-2)" "unprognostic (1.36e-1)" "unprognostic (7.30e-2)" "unprognostic (4.36e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-3)" "unprognostic (9.04e-2)" "unprognostic (3.14e-2)" "unprognostic (1.58e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (5.03e-4)" "unprognostic (3.68e-3)" "unprognostic (1.05e-1)" "unprognostic (1.31e-2)" "unprognostic (7.70e-2)" S100A13 ENSG00000189171 "S100 calcium binding protein A13" Q99584 1 153618787-153631360 "Predicted intracellular proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 743.6;Proximal tubular cells: 574.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 33.3" "Group enriched" "Detected in all" 5 "dendritic cells: 13.7;NK-cells: 33.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019592, CAB025494" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" "Secreted in other tissues" Transport NA NA 36000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" 2 "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "CAB025494: , HPA019592: AB_10601499" "unprognostic (1.50e-2)" "unprognostic (9.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.45e-1)" "unprognostic (7.77e-2)" "unprognostic (9.72e-3)" "unprognostic (1.75e-3)" "unprognostic (9.93e-2)" "unprognostic (6.48e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.83e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.43e-2)" "unprognostic (8.10e-2)" "unprognostic (1.82e-3)" "unprognostic (1.72e-2)" S100A4 "18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98" ENSG00000196154 "S100 calcium binding protein A4" P26447 1 153543613-153550136 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1075.2" "Cell type enhanced" "Detected in many" "granulocytes: 2096.4;Hofbauer cells: 3323.4;Kupffer cells: 2196.3;Langerhans cells: 6590.0;Macrophages: 2857.6;monocytes: 4686.6;T-cells: 1915.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 2211.4" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "spinal cord: 52.5" "CAB002618, HPA007973, CAB027387, CAB058698, CAB068227, CAB068228" Enhanced Supported Nucleoplasm,Cytosol "Secreted to blood" "No annotated function" NA NA 9600000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 13 Nucleoplasm Cytosol "CAB002618: , CAB027387: , CAB058698: AB_2665603, CAB068227: AB_2665602, CAB068228: AB_2665601, HPA007973: AB_1079858" "unprognostic (1.56e-1)" "unprognostic (6.10e-2)" "unprognostic (2.84e-2)" "unprognostic (8.20e-2)" "unprognostic (6.21e-2)" "prognostic favorable (4.03e-5)" "unprognostic (8.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.50e-1)" "unprognostic (2.20e-1)" "unprognostic (2.78e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.05e-1)" "unprognostic (3.05e-1)" "unprognostic (2.76e-2)" "unprognostic (3.16e-2)" S100A7 "PSOR1, S100A7c" ENSG00000143556 "S100 calcium binding protein A7" P31151 1 153457744-153460651 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 1036.0;lymphoid tissue: 1202.2;skin 1: 336.5;vagina: 990.0" "Group enriched" "Detected in some" 10 "Basal keratinocytes: 2303.5;granulocytes: 727.6;Serous glandular cells: 2137.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 1201.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "head and neck cancer: 469.5" "CAB001453, HPA006997, CAB033766" Enhanced Supported Cytosol "Secreted in other tissues" "No annotated function" NA NA 14000000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 2 Cytosol "CAB001453: AB_564004, CAB033766: AB_2269963, HPA006997: AB_1079860" "unprognostic (3.28e-1)" "unprognostic (9.85e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-2)" "unprognostic (3.17e-1)" "unprognostic (2.94e-2)" "unprognostic (1.03e-2)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (2.99e-1)" "unprognostic (5.41e-2)" "unprognostic (1.21e-2)" S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP-8, MRP8, P8, S100-A8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34972.5;esophagus: 23877.2;vagina: 10830.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 9603.9;Kupffer cells: 6254.3;Serous glandular cells: 4860.9;Squamous epithelial cells: 10605.6;Suprabasal keratinocytes: 41015.2" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Region enhanced" "Detected in all" "cerebral cortex: 66.1" "Group enriched" "Detected in all" 9 "classical monocyte: 26966.7;neutrophil: 53446.0" "Group enriched" "Detected in all" 9 "granulocytes: 53446.0;monocytes: 26966.7" "Group enriched" "Detected in many" 6 "breast cancer: 333.1;cervical cancer: 581.7;head and neck cancer: 730.8" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" Immunity NA NA 10900000 370000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 3 "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP-14, MRP14, NIF, P14, S100-A9" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31844.0;esophagus: 29726.6;vagina: 13605.6" "Cell type enriched" "Detected in many" 4 "Suprabasal keratinocytes: 51199.6" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Region enhanced" "Detected in all" "cerebral cortex: 97.1" "Group enriched" "Detected in all" 6 "classical monocyte: 24645.2;neutrophil: 33874.3" "Group enriched" "Detected in all" 6 "granulocytes: 33874.3;monocytes: 24645.2" "Cancer enhanced" "Detected in many" "breast cancer: 536.0;head and neck cancer: 1157.4" "Breast - Macrophages, Colon - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA004193, CAB009441, CAB080262" Enhanced Supported "Plasma membrane,Intermediate filaments,Cytosol" "Secreted to blood" Immunity NA NA 10600000 1200000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 8 "Plasma membrane, Intermediate filaments, Cytosol" "CAB009441: AB_2184420, CAB080262: , HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" SAA1 "PIG4, SAA, TP53I4" ENSG00000173432 "Serum amyloid A1" P0DJI8 11 18266260-18269977 "Disease related genes, Predicted secreted proteins" "Acute phase" Heparin-binding Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 46934.0" "Cell type enriched" "Detected in many" 9 "Hepatocytes: 88360.6" "Cancer enriched" "Detected in many" 16 "liver cancer: 1249.6" "Group enriched" "Detected in many" 5 "choroid plexus: 3.7;pons: 8.3;thalamus: 14.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 445.5" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Secreted to blood" "Acute phase" NA NA 300000000 11000000000 "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Hepatocytes - Metabolism" "unprognostic (2.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.82e-1)" "unprognostic (1.50e-1)" "unprognostic (4.54e-3)" "unprognostic (1.79e-2)" "unprognostic (1.63e-2)" "unprognostic (7.04e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-2)" "unprognostic (8.95e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.57e-12)" "unprognostic (5.15e-2)" "unprognostic (9.78e-2)" "unprognostic (9.23e-3)" "unprognostic (1.64e-1)" SAA2 ENSG00000134339 "Serum amyloid A2" P0DJI9 11 18239223-18248668 "Disease related genes, Predicted secreted proteins" "Acute phase" Amyloidosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 35358.8" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 43517.4" "Cancer enriched" "Detected in many" 22 "liver cancer: 150.5" "Group enriched" "Detected in all" 4 "pons: 17.8;thalamus: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 394.0" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Secreted to blood" "Acute phase" NA NA 50000000 9200000000 "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Hepatocytes - Metabolism" 2 "unprognostic (1.73e-3)" "unprognostic (4.42e-2)" "unprognostic (2.63e-1)" "unprognostic (5.03e-2)" "unprognostic (1.40e-3)" "unprognostic (7.12e-2)" "unprognostic (7.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.57e-1)" "unprognostic (2.86e-2)" "unprognostic (2.78e-2)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.30e-8)" "unprognostic (1.53e-1)" "unprognostic (9.72e-2)" "unprognostic (7.62e-3)" "unprognostic (1.28e-1)" SAA4 "C-SAA, CSAA" ENSG00000148965 "Serum amyloid A4, constitutive" P35542 11 18231355-18236802 "Plasma proteins, Predicted secreted proteins" "Acute phase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 125 "liver: 1879.5" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1673.3" "Cancer enriched" "Detected in many" 141 "liver cancer: 118.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.4;head and neck cancer: 6.3;liver cancer: 5.5" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "CAB026061, HPA060139" Supported "Secreted to blood" "Acute phase" NA NA 65000000000 33000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "CAB026061: , HPA060139: AB_2684210" "unprognostic (4.70e-4)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (4.83e-1)" "unprognostic (4.15e-2)" "unprognostic (6.05e-2)" "unprognostic (3.63e-3)" "unprognostic (5.94e-2)" "unprognostic (2.40e-2)" "unprognostic (1.41e-1)" "unprognostic (7.35e-2)" "unprognostic (2.54e-8)" "unprognostic (2.49e-1)" "unprognostic (6.46e-2)" SAMD1 ENSG00000141858 "Sterile alpha motif domain containing 1" 19 14087851-14091036 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA041662, HPA049059" Uncertain Approved Mitochondria,Cytosol "Intracellular and membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 33: Non-specific - DNA binding" Cytosol Mitochondria "HPA041662: AB_2677605, HPA049059: AB_2680616" "unprognostic (2.93e-2)" "prognostic favorable (7.41e-4)" "unprognostic (8.43e-2)" "unprognostic (3.30e-1)" "unprognostic (1.56e-2)" "unprognostic (1.72e-2)" "prognostic unfavorable (1.96e-5)" "unprognostic (2.66e-1)" "unprognostic (9.92e-2)" "unprognostic (3.86e-3)" "unprognostic (9.26e-3)" "unprognostic (4.00e-1)" "prognostic unfavorable (7.98e-5)" "prognostic favorable (8.31e-4)" "unprognostic (1.68e-2)" "unprognostic (3.29e-2)" "unprognostic (2.45e-1)" SAP30 ENSG00000164105 "Sin3A associated protein 30" O75446 4 173369969-173377532 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 110.6;monocytes: 278.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022627, HPA059012" Enhanced Supported Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" 8 Nucleoplasm "CAB022627: , HPA059012: AB_2683880" "unprognostic (1.53e-1)" "unprognostic (3.67e-2)" "unprognostic (3.26e-1)" "unprognostic (1.39e-1)" "unprognostic (5.83e-2)" "unprognostic (8.71e-2)" "prognostic unfavorable (1.24e-6)" "unprognostic (4.95e-2)" "unprognostic (7.23e-2)" "unprognostic (3.93e-2)" "unprognostic (4.48e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (3.97e-1)" "unprognostic (5.70e-2)" "unprognostic (1.30e-1)" "unprognostic (2.21e-1)" SARM1 "KIAA0524, SAMD2, SARM" ENSG00000004139 "Sterile alpha and TIR motif containing 1" Q6SZW1 17 28364356-28404049 "Enzymes, Predicted intracellular proteins" "Differentiation, Immunity, Innate immunity, Neurogenesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.4;Excitatory neurons: 22.7;Horizontal cells: 23.3;Inhibitory neurons: 27.6;Oligodendrocyte precursor cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024359, HPA024759" Uncertain Supported Mitochondria "Intracellular and membrane" Immunity NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 25: Bipolar cells - Visual perception" 2 Mitochondria "HPA024359: AB_1856582, HPA024759: AB_1856581" "unprognostic (1.40e-4)" "unprognostic (9.00e-2)" "unprognostic (2.47e-1)" "unprognostic (2.41e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.27e-2)" "unprognostic (1.87e-2)" "unprognostic (7.01e-2)" "unprognostic (2.49e-4)" "unprognostic (6.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (4.84e-2)" "unprognostic (7.62e-4)" SBSN "HLAR698, UNQ698" ENSG00000189001 Suprabasin Q6UWP8 19 35523367-35528351 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1026.5;skin 1: 2366.6;vagina: 733.6" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 5858.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 355.2;melanoma: 153.1" "Region enriched" "Detected in some" 7 "basal ganglia: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 38.8;head and neck cancer: 19.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062568, HPA067734" Enhanced Approved Vesicles "Secreted - unknown location" "No annotated function" NA NA 89000000 "Cluster 13: Skin - Cornification" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" Vesicles "HPA062568: AB_2684794, HPA067734: AB_2685894" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-3)" "unprognostic (3.45e-3)" "unprognostic (2.56e-1)" "unprognostic (4.83e-4)" "unprognostic (4.31e-4)" "unprognostic (6.97e-2)" "unprognostic (9.08e-14)" "unprognostic (6.37e-2)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (1.36e-3)" SBSPON "C8orf84, RPESP" ENSG00000164764 "Somatomedin B and thrombospondin type 1 domain containing" Q8IVN8 8 73064543-73124088 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 57.3;Collecting duct cells: 46.7;Lymphatic endothelial cells: 42.7;Muller glia cells: 44.0;Schwann cells: 111.2;Secretory cells: 44.4;Smooth muscle cells: 42.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "white matter: 36.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 8.8" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA029595 Approved Approved Vesicles "Secreted to extracellular matrix" "No annotated function" NA NA 40000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 22: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 3: Basal prostatic cells - Lipid metabolism" Vesicles "HPA029595: AB_10600763" "prognostic favorable (7.18e-4)" "unprognostic (5.08e-3)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (1.75e-1)" "unprognostic (2.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.65e-2)" "unprognostic (2.92e-1)" "unprognostic (1.46e-1)" "unprognostic (9.54e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (6.14e-2)" "unprognostic (3.54e-1)" "unprognostic (2.12e-2)" "unprognostic (6.25e-2)" SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.0" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Endothelial cells: 46.2;Langerhans cells: 44.6;Lymphatic endothelial cells: 44.5;Microglial cells: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Receptor NA NA 2000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 18 "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" SCG2 "CHGC, SgII, SN" ENSG00000171951 "Secretogranin II" P13521 2 223596940-223602361 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 349.2;brain: 368.9;pituitary gland: 261.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 141.1;Enteroendocrine cells: 287.9;Horizontal cells: 115.8;Inhibitory neurons: 104.6;Pancreatic endocrine cells: 436.4" "Group enriched" "Detected in many" 8 "glioma: 70.0;pancreatic cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 319.4;Rhabdoid: 457.9" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011893, HPA075062" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" "No annotated function" NA NA 330000 "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" 2 "Golgi apparatus" Vesicles "HPA011893: AB_1856656, HPA075062: AB_2732277" "unprognostic (2.93e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-3)" "unprognostic (6.82e-4)" "unprognostic (2.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-3)" "unprognostic (6.73e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "prognostic favorable (5.58e-4)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.01e-10)" "unprognostic (2.47e-3)" "unprognostic (4.02e-1)" "unprognostic (1.57e-2)" "unprognostic (1.90e-3)" SCG3 "FLJ90833, SgIII" ENSG00000104112 "Secretogranin III" Q8WXD2 15 51681492-51721026 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 161.3;pituitary gland: 38.3;retina: 55.0" "Cell type enhanced" "Detected in some" "Astrocytes: 75.2;Bipolar cells: 116.6;Cone photoreceptor cells: 249.8;Enteroendocrine cells: 63.2;Horizontal cells: 90.6;Inhibitory neurons: 61.3;Oligodendrocyte precursor cells: 59.4;Pancreatic endocrine cells: 159.6;Rod photoreceptor cells: 82.1" "Group enriched" "Detected in many" 7 "glioma: 41.0;pancreatic cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Neuroblastoma: 62.1;thyroid cancer: 100.9" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Spermatocytes, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006880, CAB033274, HPA053715" Enhanced Supported Supported Vesicles "Secreted in brain" "No annotated function" NA NA 3100000 "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" 1 Vesicles "CAB033274: AB_2302033, HPA006880: AB_1079898, HPA053715: AB_2682239" "unprognostic (1.38e-2)" "unprognostic (2.42e-1)" "unprognostic (1.40e-1)" "unprognostic (5.24e-5)" "unprognostic (1.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.74e-1)" "unprognostic (9.93e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (8.17e-2)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.78e-1)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" SCG5 "7B2, SGNE1, SgV" ENSG00000166922 "Secretogranin V" P05408 15 32641676-32697098 "Predicted secreted proteins" Transport "Chaperone, Neuropeptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 247.6;choroid plexus: 357.2;pituitary gland: 391.9" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 277.8;Pancreatic endocrine cells: 575.6" "Group enriched" "Detected in many" 5 "glioma: 38.2;pancreatic cancer: 82.9;thyroid cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 101.8" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013136, HPA074618" Supported "Secreted to blood" Neuropeptide NA NA 100000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" 3 "HPA013136: AB_1856657, HPA074618: AB_2732262" "unprognostic (1.71e-1)" "unprognostic (9.87e-2)" "unprognostic (7.94e-2)" "unprognostic (1.30e-2)" "unprognostic (3.59e-3)" "prognostic unfavorable (9.64e-4)" "unprognostic (2.69e-1)" "unprognostic (1.27e-3)" "unprognostic (4.69e-2)" "unprognostic (1.97e-1)" "unprognostic (5.62e-3)" "unprognostic (3.92e-1)" "prognostic unfavorable (4.51e-9)" "unprognostic (3.57e-2)" "unprognostic (8.13e-2)" "unprognostic (3.08e-3)" "unprognostic (8.88e-2)" SCGB1A1 "CC10, CC16, CCSP, UGB" ENSG00000149021 "Secretoglobin family 1A member 1" P11684 11 62405103-62423195 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Phospholipase A2 inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lung: 2979.8" "Group enriched" "Detected in some" 5 "Club cells: 65464.2;Ionocytes: 25176.2" "Cancer enriched" "Detected in many" 8 "lung cancer: 215.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 11 "Esophageal cancer: 174.9;Gallbladder cancer: 111.1;head and neck cancer: 48.1;pancreatic cancer: 75.7" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025686, HPA031828" Enhanced "Secreted in other tissues" "Enzyme inhibitor" NA NA 13000000 "Cluster 57: Lung - Lung function" "Cluster 16: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 7 "CAB025686: , HPA031828: AB_2674061" "unprognostic (2.40e-3)" "unprognostic (1.55e-2)" "unprognostic (5.46e-2)" "unprognostic (2.70e-2)" "unprognostic (4.69e-3)" "unprognostic (2.12e-2)" "unprognostic (1.23e-2)" "unprognostic (2.31e-2)" "unprognostic (2.63e-2)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" SCGB1C1 RYD5 ENSG00000188076 "Secretoglobin family 1C member 1" Q8TD33 11 193078-194575 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 1.4;retina: 3.3;salivary gland: 1.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 32 "basophil: 4.9;neutrophil: 1.3" "Lineage enriched" "Detected in single" 50 "granulocytes: 4.9" "Not detected" "Not detected" "Secreted - unknown location" "No annotated function" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 76: Retina - Visual perception" "Cluster 15: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 57: Platelets - Hemostasis" "unprognostic (5.09e-3)" SCGB1C2 ENSG00000268320 "Secretoglobin family 1C member 2" P0DMR2 17 137569-139067 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "pancreas: 1.4" "Group enriched" "Detected in some" 6 "Late spermatids: 1.0;Muller glia cells: 3.1" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Platelets - Hemostasis" "unprognostic (4.65e-2)" SCGB1D1 "LIPA, LPHA, MGC71958" ENSG00000168515 "Secretoglobin family 1D member 1" O95968 11 62190216-62193539 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "cervix: 1.2" "Cell type enriched" "Detected in single" 7 "Secretory cells: 1.2" "Group enriched" "Detected in some" 40 "endometrial cancer: 23.3;ovarian cancer: 16.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Glandular & Luminal cells - Unknown function" 5 "unprognostic (6.95e-3)" "unprognostic (9.01e-2)" SCGB1D2 "LIPB, LPHB" ENSG00000124935 "Secretoglobin family 1D member 2" O95969 11 62242239-62244812 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 1181.9;cervix: 3857.0" "Cell type enriched" "Detected in many" 4 "Glandular and luminal cells: 3304.2" "Group enriched" "Detected in many" 6 "breast cancer: 625.1;endometrial cancer: 226.0" "Region enhanced" "Detected in all" "choroid plexus: 21.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "breast cancer: 256.6" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells" HPA035318 Approved "Secreted in other tissues" "No annotated function" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA035318: AB_10610421" "unprognostic (8.76e-2)" "unprognostic (2.14e-1)" "prognostic favorable (3.46e-6)" "unprognostic (2.39e-2)" "unprognostic (5.89e-2)" "unprognostic (4.72e-2)" "unprognostic (1.99e-1)" "unprognostic (6.43e-2)" "prognostic favorable (8.03e-6)" "unprognostic (1.55e-1)" "unprognostic (1.15e-2)" SCGB1D4 IIS ENSG00000197745 "Secretoglobin family 1D member 4" Q6XE38 11 62296281-62299075 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "cervix: 50.4;endometrium 1: 15.1;epididymis: 42.6;fallopian tube: 52.2" "Group enriched" "Detected in some" 5 "Ciliated cells: 1028.5;Glandular and luminal cells: 558.1" "Cancer enriched" "Detected in some" 57 "endometrial cancer: 100.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Secreted in other tissues" "No annotated function" NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "unprognostic (2.26e-3)" "unprognostic (3.20e-1)" SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 1947.5;epididymis: 1337.7" "Group enriched" "Detected in many" 4 "Ciliated cells: 870.3;Glandular and luminal cells: 2561.3" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 971.9" "Region enhanced" "Detected in some" "medulla oblongata: 7.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 15.0" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" Vesicles "HPA034584: AB_10602221" "unprognostic (7.73e-2)" "unprognostic (3.77e-1)" "prognostic favorable (1.22e-4)" "prognostic favorable (1.54e-8)" "unprognostic (2.98e-2)" "unprognostic (1.86e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (6.87e-3)" "prognostic favorable (6.36e-4)" "unprognostic (5.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" "unprognostic (3.35e-1)" SCGB2A2 "MGB1, MGC71974, PSBP1, UGB2" ENSG00000110484 "Secretoglobin family 2A member 2" Q13296 11 62270158-62273160 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "breast: 2712.3;skin 1: 685.3" "Group enriched" "Detected in some" 9 "Breast glandular cells: 1711.3;Breast myoepithelial cells: 1329.0;Melanocytes: 1276.4" "Cancer enriched" "Detected in many" 23 "breast cancer: 823.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 161 "breast cancer: 2165.1" "Skin - Eccrine sweat gland cells" "Region enhanced" "Detected in single" "cerebellum: 1.9" CAB026270 Enhanced "Secreted in female reproductive system" "No annotated function" NA NA "Cluster 73: Breast - Lactation" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 1 "CAB026270: AB_912980" "unprognostic (2.38e-1)" "unprognostic (7.28e-2)" "prognostic favorable (9.57e-8)" "unprognostic (4.17e-1)" "unprognostic (3.75e-1)" SCGB2B2 "SCGB4A2, SCGBL" ENSG00000205209 "Secretoglobin family 2B member 2" Q4G0G5 19 34590644-34677159 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 8.4" "Cell type enhanced" "Detected in some" "Astrocytes: 60.4;Excitatory neurons: 31.7;Inhibitory neurons: 43.4;Late spermatids: 32.9;Microglial cells: 17.0;Oligodendrocyte precursor cells: 49.5;Oligodendrocytes: 96.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Eccrine sweat gland cells, Testis - Late spermatids" HPA046806 Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 8: Neurons - Neuronal signaling" 1 "HPA046806: AB_10962373" "unprognostic (9.99e-2)" "unprognostic (3.62e-1)" "unprognostic (9.51e-2)" "unprognostic (1.38e-5)" "unprognostic (4.80e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-2)" "unprognostic (2.73e-2)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-3)" "unprognostic (3.67e-1)" "unprognostic (3.52e-2)" "unprognostic (2.90e-1)" "unprognostic (2.49e-1)" "unprognostic (3.40e-2)" "unprognostic (1.52e-1)" SCGB3A1 "HIN-1, HIN1, LU105, PnSP-2, UGRP2" ENSG00000161055 "Secretoglobin family 3A member 1" Q96QR1 5 180590105-180591499 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 259.9;lung: 492.9;salivary gland: 724.7" "Group enriched" "Detected in many" 4 "Club cells: 32504.6;Ionocytes: 15631.2" "Group enriched" "Detected in many" 7 "endometrial cancer: 114.2;lung cancer: 288.1" "Group enriched" "Detected in many" 7 "choroid plexus: 24.2;hypothalamus: 11.7" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 52.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.0" "Breast - Breast glandular cells (progenitors), Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" Cytokine NA NA 10000000 "Cluster 25: Non-specific - Unknown function" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" "unprognostic (7.70e-3)" "unprognostic (4.90e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.36e-2)" "unprognostic (7.87e-3)" "unprognostic (2.00e-2)" "unprognostic (3.20e-1)" "unprognostic (4.88e-2)" "unprognostic (3.55e-2)" "unprognostic (7.19e-2)" "unprognostic (8.74e-3)" "unprognostic (5.43e-2)" "unprognostic (4.62e-1)" "unprognostic (4.50e-1)" "unprognostic (1.50e-2)" SCGB3A2 "LU103, PNSP1, UGRP1" ENSG00000164265 "Secretoglobin family 3A member 2" Q96PL1 5 147870682-147882191 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 123 "lung: 1229.1" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 1445.1;Club cells: 1181.3" "Cancer enriched" "Detected in some" 10 "lung cancer: 211.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 50 "basophil: 72.2" "Lineage enriched" "Detected in many" 50 "granulocytes: 72.2" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA 800000 "Cluster 46: Basophils - Proteolysis" "Cluster 57: Lung - Lung function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Rhabdoid - Membrane components" "Cluster 72: Alveolar cells - Lung function" "unprognostic (3.85e-1)" "unprognostic (1.77e-1)" "unprognostic (2.99e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-2)" "unprognostic (3.17e-2)" "unprognostic (1.05e-2)" "unprognostic (1.90e-8)" "unprognostic (9.31e-3)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (9.11e-2)" SCGN "CALBL, DJ501N12.8, SECRET, SEGN" ENSG00000079689 "Secretagogin, EF-hand calcium binding protein" O76038 6 25652201-25701783 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.6;pancreas: 45.6;pituitary gland: 34.1" "Cell type enhanced" "Detected in some" "Cholangiocytes: 103.0;Enteroendocrine cells: 475.4;Pancreatic endocrine cells: 129.0" "Cancer enhanced" "Detected in many" "pancreatic cancer: 38.2;renal cancer: 22.6" "Group enriched" "Detected in many" 6 "cerebellum: 35.9;hippocampal formation: 28.2;hypothalamus: 92.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Gastric cancer: 8.1;lung cancer: 19.8;Neuroblastoma: 6.9;prostate cancer: 9.7;thyroid cancer: 7.0" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Region enriched" "Detected in many" 16 "olfactory bulb: 82.0" "Region enriched" "Detected in many" 10 "olfactory bulb: 183.0" "CAB004005, HPA006641, CAB044060, CAB062563, CAB068232" Enhanced Supported Supported Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" Cytosol "CAB004005: , CAB044060: , CAB062563: AB_2665612, CAB068232: AB_2665613, HPA006641: AB_1079874" "unprognostic (8.15e-2)" "unprognostic (4.31e-3)" "unprognostic (1.46e-1)" "unprognostic (1.25e-2)" "unprognostic (4.70e-1)" "unprognostic (1.78e-2)" "unprognostic (2.01e-1)" "unprognostic (5.14e-2)" "unprognostic (5.41e-2)" "unprognostic (9.45e-2)" "unprognostic (1.19e-1)" SCN1B ENSG00000105711 "Sodium voltage-gated channel beta subunit 1" Q07699 19 35030470-35040449 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 278.8;skeletal muscle: 551.8;tongue: 218.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 65.8;Excitatory neurons: 48.8;Horizontal cells: 63.6;Inhibitory neurons: 46.5;Skeletal myocytes: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 23.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 536.8" "Secreted in other tissues" Transport NA NA "Cluster 79: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 57: Platelets - Hemostasis" "unprognostic (8.18e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-2)" "unprognostic (6.40e-2)" "unprognostic (1.17e-2)" "unprognostic (2.69e-2)" "unprognostic (4.40e-2)" "unprognostic (1.20e-1)" "unprognostic (3.34e-2)" "unprognostic (4.72e-3)" "prognostic favorable (1.38e-4)" "unprognostic (2.25e-1)" "unprognostic (2.05e-2)" "unprognostic (9.68e-3)" "unprognostic (5.81e-2)" "unprognostic (4.12e-2)" "unprognostic (4.78e-2)" SCPEP1 RISC ENSG00000121064 "Serine carboxypeptidase 1" Q9HB40 17 56978129-57006768 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 291.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 420.9;Ciliated cells: 226.5;Club cells: 252.3;Salivary duct cells: 227.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 319.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039102, HPA057200" Enhanced Approved "Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Golgi apparatus" "HPA039102: AB_10673605, HPA057200: AB_2683365" "unprognostic (5.83e-3)" "unprognostic (7.43e-3)" "unprognostic (4.47e-2)" "unprognostic (2.96e-1)" "unprognostic (9.26e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.96e-5)" "unprognostic (1.00e-3)" "unprognostic (1.68e-1)" "unprognostic (1.70e-1)" "unprognostic (3.56e-3)" "unprognostic (1.40e-1)" "unprognostic (3.25e-1)" "unprognostic (7.28e-2)" "unprognostic (8.89e-2)" "unprognostic (8.33e-2)" "unprognostic (1.68e-1)" SCRG1 SCRG-1 ENSG00000164106 "Stimulator of chondrogenesis 1" O75711 4 173384701-173406380 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 41.6;testis: 10.5" "Cell type enhanced" "Detected in many" "Astrocytes: 44.0;Melanocytes: 49.8;Muller glia cells: 136.2;Oligodendrocyte precursor cells: 95.7;Sertoli cells: 92.5" "Cancer enriched" "Detected in many" 6 "glioma: 35.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Brain cancer: 2.0;skin cancer: 2.2" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012882 Approved "Secreted in brain" "No annotated function" NA NA 240000 "Cluster 20: Non-specific - DNA binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 4 "HPA012882: AB_1856635" "unprognostic (1.09e-1)" "unprognostic (1.83e-2)" "unprognostic (2.60e-5)" "unprognostic (2.58e-1)" "unprognostic (3.22e-2)" "unprognostic (7.51e-2)" "unprognostic (3.58e-2)" "unprognostic (1.14e-3)" "unprognostic (2.08e-1)" "unprognostic (2.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (3.95e-10)" "unprognostic (4.86e-2)" "unprognostic (2.21e-1)" "unprognostic (4.34e-3)" "unprognostic (8.74e-4)" SCT ENSG00000070031 Secretin P09683 11 626309-627181 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 42.8" "Group enriched" "Detected in some" 10 "dendritic cells: 379.7;Enteroendocrine cells: 1270.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 137 "plasmacytoid DC: 126.8" "Lineage enriched" "Detected in single" 137 "dendritic cells: 126.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050961 Enhanced "Secreted to blood" Hormone NA NA 571000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 25: Small intestine - Absorption" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" 2 "HPA050961: AB_2681291" "unprognostic (5.28e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (3.70e-4)" "unprognostic (2.72e-1)" "unprognostic (7.91e-2)" "unprognostic (1.73e-1)" "unprognostic (2.43e-3)" "unprognostic (4.19e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-2)" "unprognostic (1.88e-1)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (8.37e-2)" "unprognostic (5.45e-1)" "unprognostic (6.09e-2)" "unprognostic (1.13e-1)" SCUBE1 ENSG00000159307 "Signal peptide, CUB domain and EGF like domain containing 1" Q8IWY4 22 43197280-43343372 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 24.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 11.6;Extravillous trophoblasts: 16.8;Leydig cells: 7.1;Ovarian stromal cells: 14.6;Peritubular cells: 42.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003190 Approved "Secreted to blood" "No annotated function" NA NA 2170000 190000 "Cluster 66: Non-specific - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 66: Non-specific - Mitochondria" "Cluster 6: Ovarian stromal cells - Transcription" "HPA003190: AB_1079882" "unprognostic (5.29e-2)" "unprognostic (7.15e-6)" "unprognostic (6.03e-3)" "unprognostic (8.33e-2)" "unprognostic (3.65e-1)" "unprognostic (4.55e-2)" "unprognostic (1.34e-1)" "unprognostic (5.76e-2)" "unprognostic (1.10e-1)" "unprognostic (1.99e-1)" "unprognostic (3.74e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-2)" "unprognostic (1.02e-2)" "unprognostic (2.70e-1)" "unprognostic (2.30e-1)" "unprognostic (6.87e-3)" SCUBE2 "Cegb1, Cegf1, FLJ16792" ENSG00000175356 "Signal peptide, CUB domain and EGF like domain containing 2" Q9NQ36 11 9019476-9138114 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 47.6" "Cell type enhanced" "Detected in many" "Adipocytes: 36.3;Breast glandular cells: 50.9;Breast myoepithelial cells: 45.6;Club cells: 28.8;Melanocytes: 20.6" "Cancer enhanced" "Detected in all" "breast cancer: 54.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.0" "Lineage enriched" "Detected in single" 6 "monocytes: 1.0" "Group enriched" "Detected in some" 5 "breast cancer: 27.2;skin cancer: 7.3" "Heart muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in some" 4 "olfactory bulb: 4.6;thalamus: 2.7" "Low region specificity" "Detected in all" "HPA006353, HPA029871" Uncertain "Secreted to blood" "Developmental protein" NA NA 1100000 "Cluster 53: Non-specific - Glycosylation" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "HPA006353: AB_1856642, HPA029871: AB_10602299" "prognostic favorable (2.41e-4)" "unprognostic (5.72e-3)" "unprognostic (2.91e-1)" "unprognostic (1.76e-2)" "unprognostic (2.73e-1)" "unprognostic (6.12e-4)" "unprognostic (3.11e-1)" "unprognostic (6.39e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (1.54e-2)" "unprognostic (3.04e-1)" "unprognostic (1.94e-2)" "unprognostic (9.12e-4)" "unprognostic (4.35e-1)" "unprognostic (5.94e-2)" "unprognostic (2.88e-1)" SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "thyroid gland: 28.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 7.1;Horizontal cells: 8.2;Rod photoreceptor cells: 10.4;Smooth muscle cells: 6.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 11.1;testis cancer: 9.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Supported "Plasma membrane" "Secreted to blood" "No annotated function" NA NA 1890000 490000 "Cluster 51: Thyroid gland - Unknown function" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 "Plasma membrane" "HPA040606: AB_10795383" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-8)" "unprognostic (1.54e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.06e-3)" SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 477.8;liver: 472.9;skin 1: 433.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 232.8;Cholangiocytes: 259.5;Hepatocytes: 515.2;Squamous epithelial cells: 275.0;Suprabasal keratinocytes: 456.1;Syncytiotrophoblasts: 421.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 36.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 564.7" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" "No annotated function" NA NA 63100000 3100000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "Focal adhesion sites" "CAB002424: AB_442050, HPA006185: AB_1857705, HPA067477: " "prognostic unfavorable (2.22e-4)" "unprognostic (6.80e-3)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (4.02e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (3.66e-1)" "unprognostic (2.27e-3)" "unprognostic (1.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.62e-2)" "unprognostic (1.52e-1)" SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 398.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 602.0;Exocrine glandular cells: 496.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" "No annotated function" NA NA 320000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 5 "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" SDCBP "MDA-9, SYCL" ENSG00000137575 "Syndecan binding protein" O00560 8 58552924-58582859 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 872.6;Langerhans cells: 1044.9;Melanocytes: 1102.9;monocytes: 1174.3" "Cancer enriched" "Detected in all" 4 "melanoma: 244.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1915.9" "Group enriched" "Detected in all" 5 "granulocytes: 1915.9;monocytes: 563.2" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012245, HPA023840" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 1300000 "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 29: Monocytes - Innate immune response" 240 "Nucleoplasm, Cytosol" "Nuclear membrane" "CAB012245: , HPA023840: AB_1857712" "unprognostic (2.39e-2)" "unprognostic (3.34e-2)" "unprognostic (1.84e-2)" "unprognostic (4.45e-2)" "unprognostic (9.15e-2)" "unprognostic (2.60e-3)" "unprognostic (7.14e-2)" "unprognostic (1.04e-3)" "unprognostic (1.11e-1)" "unprognostic (5.68e-2)" "unprognostic (3.05e-2)" "unprognostic (3.01e-1)" "unprognostic (1.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.92e-1)" SDF2 ENSG00000132581 "Stromal cell derived factor 2" Q99470 17 28648346-28662189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 225.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042799 Approved Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Vesicles "HPA042799: AB_10794533" "unprognostic (3.91e-1)" "unprognostic (2.79e-1)" "unprognostic (2.03e-1)" "unprognostic (5.77e-3)" "unprognostic (3.90e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.28e-3)" "unprognostic (3.20e-3)" "unprognostic (3.02e-1)" "unprognostic (1.04e-2)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (7.75e-3)" "unprognostic (6.61e-2)" SDF2L1 "AP000553.C22.4, OTTHUMT00000075032" ENSG00000128228 "Stromal cell derived factor 2 like 1" Q9HCN8 22 21642302-21644299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.7" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 400.6;Plasma cells: 800.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005638 Approved "Intracellular and membrane" "No annotated function" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 3 "HPA005638: AB_1079888" "unprognostic (1.09e-1)" "unprognostic (2.76e-2)" "unprognostic (6.17e-2)" "prognostic favorable (4.98e-5)" "unprognostic (8.81e-3)" "unprognostic (2.29e-1)" "unprognostic (9.20e-2)" "unprognostic (2.30e-1)" "unprognostic (4.92e-2)" "unprognostic (6.88e-3)" "unprognostic (1.69e-2)" "unprognostic (1.48e-1)" "unprognostic (1.63e-2)" "unprognostic (3.44e-1)" "unprognostic (1.55e-1)" "unprognostic (1.70e-1)" "unprognostic (2.79e-2)" SDF4 Cab45 ENSG00000078808 "Stromal cell derived factor 4" 1 1216931-1232031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 299.5;Proximal enterocytes: 345.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011249, HPA011895, CAB015227" Supported Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" "CAB015227: , HPA011249: AB_2668468, HPA011895: " "unprognostic (1.98e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (3.63e-1)" "unprognostic (2.38e-3)" "unprognostic (5.88e-2)" "unprognostic (7.95e-3)" "unprognostic (3.73e-3)" "unprognostic (1.06e-1)" "unprognostic (2.01e-1)" "unprognostic (8.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.04e-2)" SDHAF4 "C6orf57, Sdh8" ENSG00000154079 "Succinate dehydrogenase complex assembly factor 4" Q5VUM1 6 70566917-70589569 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031824 Supported Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Other No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 68: Cardiomyocytes - Muscle contraction" 3 Mitochondria Nucleoplasm "HPA031824: AB_10602113" "unprognostic (8.72e-2)" "unprognostic (1.64e-1)" "unprognostic (4.95e-2)" "unprognostic (9.96e-2)" "unprognostic (4.58e-1)" "unprognostic (2.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (1.42e-3)" "unprognostic (3.18e-2)" "unprognostic (3.17e-1)" "prognostic favorable (1.95e-5)" "unprognostic (2.45e-2)" "unprognostic (9.37e-2)" "unprognostic (3.05e-1)" "unprognostic (9.94e-2)" SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Host-virus interaction, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 474.3;tongue: 557.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 573.9;Proximal tubular cells: 391.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" Transport NA NA 7900 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Mixed function" 5 Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 386.7;Distal tubular cells: 424.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA045727 Approved "Intracellular and membrane" Transport NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" SECISBP2 SBP2 ENSG00000187742 "SECIS binding protein 2" Q96T21 9 89318500-89359663 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 367.4;Late spermatids: 455.8;Spermatocytes: 340.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044314, HPA054905" Approved Supported Nucleoplasm "Intracellular and membrane" Other NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 57: Platelets - Hemostasis" 2 Nucleoplasm "HPA044314: AB_10964885, HPA054905: " "unprognostic (1.07e-1)" "unprognostic (4.24e-1)" "unprognostic (1.64e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (1.21e-1)" "unprognostic (4.00e-1)" "unprognostic (8.80e-2)" "unprognostic (1.35e-2)" "unprognostic (7.18e-2)" "unprognostic (1.92e-2)" "unprognostic (1.16e-1)" "prognostic favorable (8.98e-9)" "unprognostic (5.44e-2)" "unprognostic (1.48e-1)" "unprognostic (1.98e-1)" "unprognostic (4.55e-3)" SECTM1 K12 ENSG00000141574 "Secreted and transmembrane 1" Q8WVN6 17 82321024-82334074 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 87.8" "Cell type enhanced" "Detected in many" "Kupffer cells: 86.3;Macrophages: 38.5;monocytes: 126.0;Mucus glandular cells: 48.3;Oocytes: 49.3;Proximal enterocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 155.2" "Group enriched" "Detected in many" 13 "granulocytes: 155.2;monocytes: 58.3" "Low cancer specificity" "Detected in many" "Stomach - Macrophages" "Low region specificity" "Detected in many" HPA051214 Approved "Secreted to blood" "No annotated function" NA NA 16000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 1 "HPA051214: AB_2732565" "unprognostic (2.42e-1)" "unprognostic (2.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.69e-2)" "unprognostic (4.29e-2)" "unprognostic (1.15e-2)" "unprognostic (4.55e-2)" "unprognostic (9.39e-2)" "unprognostic (3.17e-3)" "unprognostic (7.75e-3)" "unprognostic (2.10e-2)" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.43e-1)" "unprognostic (4.31e-3)" "unprognostic (2.84e-1)" "unprognostic (1.01e-1)" SEL1L "Hrd3, IBD2, SEL1L1" ENSG00000071537 "SEL1L adaptor subunit of ERAD E3 ubiquitin ligase" Q9UBV2 14 81471547-81533853 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "pancreas: 390.9" "Cell type enhanced" "Detected in all" "Plasma cells: 240.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024267 Enhanced "Intracellular and membrane" Other NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Pancreas - Proteolysis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 5 "HPA024267: AB_1856659" "unprognostic (4.94e-1)" "unprognostic (8.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.91e-1)" "unprognostic (5.93e-2)" "unprognostic (1.16e-1)" "unprognostic (3.29e-1)" "unprognostic (2.78e-1)" "unprognostic (9.97e-2)" "unprognostic (2.58e-2)" "unprognostic (2.76e-3)" "unprognostic (4.86e-1)" "unprognostic (3.31e-2)" "unprognostic (1.30e-1)" "unprognostic (4.96e-2)" "unprognostic (1.83e-2)" "unprognostic (1.25e-2)" SELENOF SEP15 ENSG00000183291 "Selenoprotein F" O60613 1 86862445-86914424 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA No 420000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 1 "unprognostic (6.15e-2)" "unprognostic (6.98e-3)" "prognostic favorable (6.53e-4)" "unprognostic (6.20e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (8.17e-4)" "prognostic unfavorable (1.98e-5)" "unprognostic (1.65e-1)" "unprognostic (6.51e-3)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-3)" "unprognostic (2.39e-2)" "unprognostic (1.09e-1)" "unprognostic (8.24e-3)" "unprognostic (1.34e-2)" SELENOM "SELM, SEPM" ENSG00000198832 "Selenoprotein M" Q8WWX9 22 31104772-31120069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Smooth muscle cells: 725.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 155.5;T-cells: 233.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008667, HPA019601" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" "No annotated function" NA NA 170000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Neuronal - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 10 "Nucleoplasm, Cytosol" "CAB008667: AB_1622762, HPA019601: AB_1856666" "unprognostic (5.29e-3)" "unprognostic (1.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.59e-3)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (1.60e-1)" "unprognostic (3.51e-3)" "unprognostic (8.31e-2)" "prognostic unfavorable (2.55e-6)" "unprognostic (1.32e-2)" "unprognostic (3.80e-1)" "unprognostic (5.20e-2)" "unprognostic (3.19e-2)" SELENON "MDRS1, RSMD1, RSS, SELN, SEPN1" ENSG00000162430 "Selenoprotein N" Q9NZV5 1 25800193-25818221 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Desmin-related myopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 95.6;Lymphatic endothelial cells: 111.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058076 Approved Uncertain Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 41: Basophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Cytosol "HPA058076: AB_2683598" "unprognostic (2.65e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-1)" "prognostic favorable (2.23e-4)" "unprognostic (1.93e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (3.40e-5)" "unprognostic (1.94e-1)" "unprognostic (4.72e-1)" "unprognostic (3.32e-3)" "unprognostic (6.01e-2)" "unprognostic (3.07e-1)" "unprognostic (1.64e-1)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (5.56e-3)" "unprognostic (5.89e-2)" SELENOO SELO ENSG00000073169 "Selenoprotein O" Q9BVL4 22 50201011-50217616 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 27.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 89.6;Late spermatids: 167.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071795, HPA079100" Approved Supported "Mitotic chromosome,Mitochondria" "Intracellular and membrane" Enzyme Yes NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 83: Liver - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 66: Non-specific - Mitochondria" "Cluster 63: Late spermatids - Spermatogenesis" Mitochondria "Mitotic chromosome" "HPA071795: , HPA079100: " "unprognostic (1.79e-1)" "unprognostic (2.07e-3)" "unprognostic (1.60e-1)" "unprognostic (2.50e-3)" "unprognostic (3.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.85e-2)" "unprognostic (5.91e-2)" "unprognostic (1.51e-1)" "unprognostic (5.62e-2)" "unprognostic (8.20e-3)" "unprognostic (8.91e-2)" "unprognostic (1.81e-2)" "unprognostic (7.31e-2)" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "prognostic favorable (8.32e-4)" SELENOP "SELP, SeP, SEPP, SEPP1" ENSG00000250722 "Selenoprotein P" P49908 5 42799880-42887392 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 2030.1;liver: 6077.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 3136.6;Proximal enterocytes: 5404.0" "Cancer enriched" "Detected in all" 4 "liver cancer: 116.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 182.2" "Liver - Hepatocytes, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA036287 Approved Uncertain "Nucleoplasm,Golgi apparatus" "Secreted to blood" "No annotated function" NA NA 2220000000 1800000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 1 "Nucleoplasm, Golgi apparatus" "HPA036287: AB_10794618" "unprognostic (7.96e-2)" "unprognostic (2.10e-1)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (6.67e-2)" "unprognostic (6.37e-2)" "unprognostic (9.22e-2)" "unprognostic (2.19e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "prognostic favorable (6.97e-6)" "unprognostic (1.35e-2)" "unprognostic (4.19e-2)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" SEMA3A "coll-1, Hsema-I, SEMA1, SEMAD, SemD" ENSG00000075213 "Semaphorin 3A" Q14563 7 83955777-84492724 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 21.9" "Cell type enhanced" "Detected in many" "Astrocytes: 55.4;Excitatory neurons: 86.7;Lymphatic endothelial cells: 78.7;Rod photoreceptor cells: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.5" "Lineage enriched" "Detected in single" 16 "monocytes: 1.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029447, HPA052235" Approved Approved Vesicles "Secreted in other tissues" "Developmental protein" NA NA 1600000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 39: Retina & Testis - Cilium" "Cluster 9: Non-specific - Receptor signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA029447: AB_10602302, HPA052235: AB_2681770" "unprognostic (1.20e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.51e-1)" "unprognostic (5.82e-2)" "unprognostic (1.37e-2)" "unprognostic (5.98e-3)" "unprognostic (2.92e-3)" "unprognostic (6.05e-3)" "unprognostic (1.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.46e-1)" "unprognostic (4.44e-2)" "unprognostic (6.18e-12)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.61e-2)" "unprognostic (1.47e-4)" SEMA3B "LUCA-1, SemA, sema5, SEMAA, semaV" ENSG00000012171 "Semaphorin 3B" Q13214 3 50267558-50277546 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 169.0;brain: 162.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 177.0;Gastric mucus-secreting cells: 196.3;Oligodendrocytes: 146.9;Proximal enterocytes: 305.7;Schwann cells: 321.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 82.3" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Lung - Alveolar cells type 1, Skin - Fibroblast_1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 36.8" HPA030651 Uncertain "Secreted in other tissues" "Developmental protein" NA NA 790000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" "HPA030651: AB_10602224" "prognostic favorable (1.27e-4)" "unprognostic (6.48e-2)" "unprognostic (5.40e-2)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (4.15e-1)" "unprognostic (1.89e-1)" "unprognostic (2.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.28e-1)" "unprognostic (1.85e-2)" "unprognostic (4.27e-1)" "unprognostic (7.99e-2)" "unprognostic (7.78e-2)" "unprognostic (3.89e-1)" "unprognostic (8.87e-3)" "unprognostic (1.69e-2)" SEMA3C "SEMAE, SemE" ENSG00000075223 "Semaphorin 3C" Q99985 7 80742538-80922359 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 89.2;Breast myoepithelial cells: 93.5;Melanocytes: 109.9;Oligodendrocytes: 208.1;Salivary duct cells: 96.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 49.7" "Lineage enriched" "Detected in many" 9 "granulocytes: 49.7" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042418 Approved "Golgi apparatus,Plasma membrane,Cytosol" "Secreted in other tissues" "Developmental protein" NA NA 13000 "Cluster 46: Basophils - Proteolysis" "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "HPA042418: AB_10797389" "unprognostic (1.93e-2)" "unprognostic (2.54e-3)" "unprognostic (4.94e-1)" "unprognostic (9.86e-2)" "unprognostic (6.74e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (9.28e-3)" "unprognostic (1.91e-3)" "unprognostic (1.39e-2)" "unprognostic (9.01e-2)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.07e-2)" "unprognostic (1.55e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-2)" SEMA3D "coll-2, Sema-Z2" ENSG00000153993 "Semaphorin 3D" O95025 7 84995553-85187056 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 39.4;thyroid gland: 34.3" "Cell type enhanced" "Detected in many" "Early spermatids: 120.9;Late spermatids: 69.0;Leydig cells: 50.0;Lymphatic endothelial cells: 126.5;Peritubular cells: 60.5;Prostatic glandular cells: 53.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 26.3;Sarcoma: 55.3" "Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011183, HPA037522" Uncertain Approved Vesicles "Secreted in other tissues" "Developmental protein" NA NA 120000 "Cluster 47: Spleen - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "HPA011183: , HPA037522: AB_10672494" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (7.58e-3)" "unprognostic (4.02e-3)" "unprognostic (9.94e-2)" "unprognostic (5.62e-2)" "unprognostic (1.63e-1)" "unprognostic (9.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.26e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-3)" "unprognostic (5.25e-3)" SEMA3E "coll-5, KIAA0331, M-SemaK, SEMAH" ENSG00000170381 "Semaphorin 3E" O15041 7 83363238-83649139 "Human disease related genes, Predicted secreted proteins" "Angiogenesis, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 49.8;Bipolar cells: 89.8;Excitatory neurons: 81.5;Mucus glandular cells: 70.2;Oligodendrocyte precursor cells: 234.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.9" "Liver - Cholangiocyte, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029419, HPA063804" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" "Developmental protein" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 1 Vesicles Nucleoplasm "HPA029419: AB_10602090, HPA063804: AB_2685127" "unprognostic (4.42e-2)" "unprognostic (1.48e-2)" "unprognostic (7.82e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-1)" "unprognostic (4.27e-2)" "unprognostic (9.36e-2)" "unprognostic (4.09e-2)" "unprognostic (3.25e-1)" "unprognostic (1.42e-1)" "unprognostic (9.09e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-6)" "unprognostic (1.32e-2)" "unprognostic (1.14e-1)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 97.9" "Cell type enhanced" "Detected in many" "Adipocytes: 38.2;Basal prostatic cells: 33.1;Bipolar cells: 23.9;Endothelial cells: 26.5;Suprabasal keratinocytes: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 84.1" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" "Developmental protein" NA NA 1700000 7900000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" SEMA3G "FLJ00014, sem2" ENSG00000010319 "Semaphorin 3G" Q9NS98 3 52433035-52445103 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 77.5;breast: 62.1" "Cell type enriched" "Detected in some" 5 "Adipocytes: 136.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "T-reg: 1.4" "Lineage enriched" "Detected in single" 15 "T-cells: 1.4" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001761 Uncertain "Secreted to blood" "Developmental protein" NA NA 5600000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "HPA001761: AB_1079902" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "unprognostic (7.08e-2)" "unprognostic (1.47e-2)" "unprognostic (2.85e-1)" "unprognostic (5.79e-4)" "unprognostic (5.20e-3)" "unprognostic (9.14e-2)" "unprognostic (5.54e-2)" "unprognostic (5.64e-2)" "unprognostic (1.34e-3)" "unprognostic (4.14e-1)" "prognostic favorable (8.86e-5)" "unprognostic (5.63e-2)" "unprognostic (2.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969504-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 59.0;Hepatocytes: 46.1;Intestinal goblet cells: 35.2;Paneth cells: 37.8;Proximal enterocytes: 45.4;Undifferentiated cells: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" "Developmental protein" NA NA 1300000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.5;placenta: 41.7" "Cell type enhanced" "Detected in many" "Astrocytes: 69.0;Cone photoreceptor cells: 85.0;Excitatory neurons: 116.5;Inhibitory neurons: 306.8;Oligodendrocytes: 130.4" "Cancer enriched" "Detected in many" 4 "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 13.0" "Adipose visceral - Mesothelial cells, Kidney - Ascending Loop of Henle cells, Liver - Hepatic stellate cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA 1100000 "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" "Golgi apparatus" "HPA043109: AB_10793941" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (3.10e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.98e-1)" "unprognostic (2.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.36e-2)" "unprognostic (7.96e-4)" "unprognostic (1.42e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.74e-2)" "unprognostic (8.56e-2)" "unprognostic (3.30e-3)" "unprognostic (2.39e-4)" SEMG1 "CT103, SEMG" ENSG00000124233 "Semenogelin 1" P04279 20 45207033-45209768 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 146 "seminal vesicle: 29372.6" "Cell type enriched" "Detected in some" 36 "Basal prostatic cells: 59968.8" "Cancer enriched" "Detected in some" 14 "prostate cancer: 20.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 239 "eosinophil: 26.9" "Lineage enriched" "Detected in single" 269 "granulocytes: 26.9" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.5" "HPA042476, HPA064892" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 7000000 "Cluster 19: Eosinophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 3: Basal prostatic cells - Lipid metabolism" "HPA042476: AB_10794799, HPA064892: AB_2732724" "unprognostic (3.71e-1)" "unprognostic (2.92e-2)" "unprognostic (1.44e-1)" "unprognostic (3.32e-1)" "unprognostic (1.11e-2)" SEMG2 SGII ENSG00000124157 "Semenogelin 2" Q02383 20 45221373-45224458 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 148 "seminal vesicle: 10054.2" "Cell type enriched" "Detected in some" 46 "Basal prostatic cells: 33217.3" "Cancer enriched" "Detected in single" 25 "prostate cancer: 9.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "HPA042767, HPA042835" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 5000000 "Cluster 62: Connective tissue - ECM organization" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 3: Basal prostatic cells - Lipid metabolism" "HPA042767: AB_10959312, HPA042835: AB_10964060" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" SERPINA1 "A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1" ENSG00000197249 "Serpin family A member 1" P01009 14 94376747-94390693 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 45 "liver: 33156.1" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 38353.1" "Cancer enriched" "Detected in all" 10 "liver cancer: 3850.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 2484.3;intermediate monocyte: 3414.0;neutrophil: 2835.2;non-classical monocyte: 4540.7" "Group enriched" "Detected in all" 5 "granulocytes: 2835.2;monocytes: 4540.7" "Cancer enhanced" "Detected in many" "Gastric cancer: 303.1;liver cancer: 783.6;lymphoma: 293.1" "Adipose visceral - Neutrophils, Liver - Hepatocytes, Skeletal muscle - Neutrophils" "Not detected" "Not detected" "HPA000927, HPA001292, CAB013211, CAB016648, CAB073396" Enhanced Enhanced Vesicles "Secreted to blood" "Blood coagulation" NA NA 2070000000000 140000000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 4 Vesicles "CAB013211: , CAB016648: AB_1611888, CAB073396: , HPA000927: AB_1844761, HPA001292: AB_1844762" "prognostic favorable (1.61e-5)" "unprognostic (3.37e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.38e-2)" "unprognostic (1.98e-2)" "unprognostic (5.50e-3)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" "unprognostic (2.54e-2)" "unprognostic (7.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.54e-1)" "unprognostic (1.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (1.96e-1)" SERPINA10 "PZI, ZPI" ENSG00000140093 "Serpin family A member 10" Q9UK55 14 94280460-94293268 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 113 "liver: 338.3" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 217.4" "Cancer enriched" "Detected in some" 51 "liver cancer: 40.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Liver - Hepatocytes, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" HPA048739 Approved Nucleoplasm,Cytosol "Secreted to blood" "Blood coagulation" NA NA 3960000000 4700000000 "Cluster 31: Liver - Plasma proteins" "Cluster 9: Non-specific - Receptor signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Hepatocytes - Metabolism" 2 Nucleoplasm Cytosol "HPA048739: AB_2797237" "unprognostic (7.14e-2)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.00e-4)" "unprognostic (6.11e-2)" "unprognostic (2.81e-4)" "unprognostic (2.31e-4)" "unprognostic (2.77e-2)" "unprognostic (2.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (7.93e-3)" SERPINA11 ENSG00000186910 "Serpin family A member 11" Q86U17 14 94442464-94452800 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 93 "liver: 475.6" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 259.5" "Cancer enriched" "Detected in some" 9 "liver cancer: 94.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "liver cancer: 4.9;lymphoma: 2.3" "Breast - Breast glandular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" "Enzyme inhibitor" NA NA 230000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "unprognostic (2.50e-2)" "unprognostic (3.26e-1)" "unprognostic (9.00e-2)" "prognostic favorable (6.30e-4)" "unprognostic (7.44e-2)" "unprognostic (2.02e-2)" "unprognostic (1.70e-1)" "unprognostic (3.44e-1)" "unprognostic (5.14e-2)" "unprognostic (1.53e-1)" "unprognostic (1.64e-1)" SERPINA12 OL-64 ENSG00000165953 "Serpin family A member 12" Q8IW75 14 94487274-94517844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 383.8" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 10.9" "Group enriched" "Detected in some" 5 "liver cancer: 1.8;melanoma: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Enzyme inhibitor" NA NA 6500000 "Cluster 82: Skin - Keratinization" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 12: Squamous epithelial cells - Keratinization" "unprognostic (1.82e-3)" "unprognostic (6.44e-2)" "unprognostic (3.25e-1)" "unprognostic (1.00e-2)" "unprognostic (5.98e-2)" "unprognostic (2.97e-2)" "unprognostic (7.64e-3)" "unprognostic (6.67e-2)" SERPINA3 "AACT, ACT" ENSG00000196136 "Serpin family A member 3" P01011 14 94612384-94624055 "Cancer-related genes, Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 8942.3;pancreas: 4764.3" "Cell type enhanced" "Detected in some" "Ductal cells: 21.1;Exocrine glandular cells: 41.9;Fibroblasts: 14.7;Hepatocytes: 11.4;Mucus glandular cells: 36.7;Serous glandular cells: 13.8" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 142.2;skin cancer: 409.0" "Breast - Breast glandular cells, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000893, HPA002560, CAB016647" Enhanced "Secreted to blood" "Acute phase" NA NA 697000000000 94000000000 "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 49: Non-specific - Transcription" 6 "CAB016647: AB_1611882, HPA000893: AB_10794315, HPA002560: AB_1856717" "prognostic favorable (8.92e-4)" "unprognostic (3.33e-3)" "unprognostic (9.21e-2)" "unprognostic (1.53e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (2.00e-2)" "unprognostic (1.00e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" "unprognostic (1.20e-2)" "unprognostic (9.92e-2)" "unprognostic (3.74e-12)" "unprognostic (6.47e-2)" "unprognostic (1.33e-2)" "unprognostic (2.02e-2)" SERPINA4 "KAL, KLST, KST, PI4" ENSG00000100665 "Serpin family A member 4" P29622 14 94561442-94569913 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 533.2" "Group enriched" "Detected in some" 7 "Cholangiocytes: 225.1;Exocrine glandular cells: 103.6;Hepatocytes: 397.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 94.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 2.3;colorectal cancer: 1.5;Gastric cancer: 2.1;liver cancer: 5.6" "Liver - Hepatocytes, Stomach - Parietal cells" "Not detected" "Not detected" "HPA003607, HPA068939" Approved Uncertain Vesicles "Secreted to blood" "Enzyme inhibitor" NA NA 14500000000 14000000000 "Cluster 83: Liver - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" Vesicles "HPA003607: AB_1079914, HPA068939: " "unprognostic (1.65e-3)" "unprognostic (4.13e-2)" "prognostic favorable (2.95e-4)" "unprognostic (2.09e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (4.03e-3)" "unprognostic (1.02e-2)" "unprognostic (2.24e-4)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" SERPINA5 "PAI3, PCI, PLANH3, PROCI" ENSG00000188488 "Serpin family A member 5" P05154 14 94561442-94593118 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Fertilization, Lipid transport, Transport" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 469.3;liver: 761.5;testis: 419.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 239.3;Cholangiocytes: 360.6;Glandular and luminal cells: 330.8;Hepatocytes: 174.8;Late spermatids: 271.4;Peritubular cells: 139.8;Sertoli cells: 356.3" "Cancer enhanced" "Detected in many" "liver cancer: 121.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 27.3;liver cancer: 67.0" "Liver - Hepatocytes, Pancreas - Macrophages, Skin - Fibroblast_2, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA078846 Enhanced "Secreted to blood" Transport NA NA 2100000000 "Cluster 78: Testis - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "HPA078846: " "unprognostic (5.94e-3)" "unprognostic (2.64e-4)" "unprognostic (1.13e-1)" "prognostic favorable (7.72e-4)" "unprognostic (3.34e-3)" "unprognostic (6.10e-3)" "unprognostic (3.94e-2)" "unprognostic (1.39e-3)" "unprognostic (5.36e-1)" "unprognostic (1.50e-1)" "unprognostic (6.16e-2)" "unprognostic (1.87e-2)" "unprognostic (8.39e-3)" "unprognostic (3.38e-3)" "unprognostic (9.92e-2)" "unprognostic (8.08e-2)" "unprognostic (3.23e-1)" SERPINA6 CBG ENSG00000170099 "Serpin family A member 6" P08185 14 94304248-94323389 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "liver: 752.4" "Group enriched" "Detected in some" 4 "Cholangiocytes: 223.2;Hepatocytes: 335.3" "Cancer enriched" "Detected in many" 9 "liver cancer: 244.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 10.6;liver cancer: 21.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA017864 Approved "Secreted to blood" Transport NA NA 60800000000 37000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "HPA017864: AB_1856721" "unprognostic (2.82e-2)" "unprognostic (1.67e-1)" "unprognostic (1.02e-3)" "prognostic favorable (6.96e-5)" "unprognostic (2.93e-3)" "unprognostic (9.98e-3)" "unprognostic (4.43e-2)" "unprognostic (3.11e-1)" "unprognostic (4.80e-3)" "unprognostic (2.94e-1)" "unprognostic (2.47e-2)" "unprognostic (4.54e-2)" "unprognostic (1.43e-1)" "unprognostic (2.14e-3)" SERPINA7 TBG ENSG00000123561 "Serpin family A member 7" P05543 X 106032435-106038727 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 611 "liver: 273.6" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 163.2" "Cancer enriched" "Detected in single" 203 "liver cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "liver cancer: 5.5" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA002803 Approved "Secreted to blood" Transport NA NA 39800000000 25000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "HPA002803: AB_1079915" "unprognostic (6.22e-2)" "unprognostic (1.63e-3)" "unprognostic (3.34e-1)" "unprognostic (2.62e-1)" "unprognostic (2.15e-3)" "unprognostic (2.95e-1)" SERPINA9 "GCET1, SERPINA11b" ENSG00000170054 "Serpin family A member 9" Q86WD7 14 94462717-94479689 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "lymphoid tissue: 70.7" "Cell type enriched" "Detected in single" 13 "B-cells: 1.9" "Cancer enriched" "Detected in single" 4 "stomach cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 43 "lymphoma: 40.6" "Region enriched" "Detected in many" 16 "basal ganglia: 71.9" "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "unprognostic (1.32e-2)" "unprognostic (1.05e-1)" "unprognostic (1.94e-2)" "unprognostic (3.89e-3)" "unprognostic (6.10e-2)" "unprognostic (6.67e-2)" "unprognostic (1.38e-2)" "unprognostic (1.16e-1)" SERPINB1 "EI, ELANH2, LEI, MNEI, PI2" ENSG00000021355 "Serpin family B member 1" P30740 6 2832332-2841959 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 461.5;esophagus: 464.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 659.9;Exocrine glandular cells: 838.4;monocytes: 795.9;Suprabasal keratinocytes: 720.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018871, HPA018882, HPA052642" Enhanced Supported "Cytoplasmic bodies" "Secreted to blood" "Enzyme inhibitor" NA NA 24000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Non-specific - Mixed function" "Cytoplasmic bodies" "HPA018871: AB_1856724, HPA018882: , HPA052642: AB_2681896" "unprognostic (1.13e-2)" "unprognostic (1.93e-1)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (5.14e-3)" "unprognostic (9.67e-2)" "unprognostic (3.59e-3)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.88e-2)" "unprognostic (1.08e-3)" "unprognostic (9.07e-2)" "unprognostic (1.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" SERPINB2 "HsT1201, PAI-2, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 231.4;lymphoid tissue: 79.0;skin 1: 86.8" "Group enriched" "Detected in many" 8 "Basal keratinocytes: 1534.4;Suprabasal keratinocytes: 665.7;Syncytiotrophoblasts: 683.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.5" "Region enhanced" "Detected in some" "cerebral cortex: 2.9;thalamus: 2.5" "Immune cell enhanced" "Detected in some" "basophil: 22.1;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.1" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 326.1" "Pancreas - Ductal cells, Skin - Keratinocyte (other)" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" "Enzyme inhibitor" NA NA 2200000 "Cluster 22: Eosinophils - Transcription" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA015480: AB_1855456, HPA076596: , HPA076608: " "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.46e-2)" "unprognostic (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-6)" "unprognostic (3.89e-2)" "unprognostic (3.94e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.55e-5)" SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 209.5;skin 1: 233.4" "Group enriched" "Detected in many" 7 "Basal keratinocytes: 712.5;Basal respiratory cells: 241.8;Basal squamous epithelial cells: 355.2;Squamous epithelial cells: 532.9;Suprabasal keratinocytes: 803.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 125.2" "Breast - Breast myoepithelial cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" "No annotated function" NA NA 770000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 1 Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" SERPINC1 "AT3, ATIII, MGC22579" ENSG00000117601 "Serpin family C member 1" P01008 1 173903800-173917327 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1350 "liver: 4902.3" "Cell type enriched" "Detected in some" 36 "Hepatocytes: 2537.3" "Cancer enriched" "Detected in some" 871 "liver cancer: 1504.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 1.6;liver cancer: 5.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001816, CAB016790, HPA024007" Supported "Secreted to blood" "Blood coagulation" NA NA 120000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "CAB016790: , HPA001816: AB_1079926, HPA024007: AB_1856732" "unprognostic (1.28e-2)" "unprognostic (2.22e-1)" "unprognostic (3.83e-2)" "unprognostic (5.98e-2)" "unprognostic (6.91e-2)" "unprognostic (1.93e-2)" "prognostic favorable (3.40e-5)" "unprognostic (1.75e-2)" "unprognostic (8.67e-2)" "unprognostic (3.48e-2)" "unprognostic (4.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.36e-2)" "unprognostic (5.28e-3)" "unprognostic (5.80e-2)" "unprognostic (6.35e-2)" "unprognostic (8.21e-2)" SERPIND1 "D22S673, HC-II, HC2, HCF2, HLS2" ENSG00000099937 "Serpin family D member 1" P05546 22 20774113-20787720 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Chemotaxis, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 1214.6" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 238.0" "Cancer enriched" "Detected in many" 80 "liver cancer: 334.4" "Region enriched" "Detected in all" 21 "choroid plexus: 191.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 15 "liver cancer: 30.6;ovarian cancer: 66.9" "Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB008639, HPA055767" Supported Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 50000000000 "Cluster 30: Non-specific - DNA binding" "Cluster 31: Liver - Plasma proteins" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 62: Hepatocytes - Metabolism" Vesicles "CAB008639: AB_1618010, HPA055767: AB_2682912" "unprognostic (1.68e-1)" "unprognostic (8.27e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.09e-4)" "unprognostic (5.42e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-3)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-9)" "unprognostic (2.01e-1)" "unprognostic (4.66e-2)" "unprognostic (8.36e-3)" "unprognostic (1.46e-1)" SERPINE1 "PAI, PAI1, PLANH1" ENSG00000106366 "Serpin family E member 1" P05121 7 101127104-101139247 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 348.4;placenta: 403.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 212.1;Ovarian stromal cells: 138.1;Pancreatic endocrine cells: 466.9;Syncytiotrophoblasts: 739.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 25 "NK-cell: 9.5" "Lineage enriched" "Detected in single" 25 "NK-cells: 9.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 1620.4" "Colon - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB068501 Uncertain "Secreted to blood" "Enzyme inhibitor" NA No 142000000 13000000 "Cluster 14: Non-specific - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 8 "CAB068501: AB_1642775" "unprognostic (5.02e-2)" "prognostic unfavorable (5.01e-4)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.10e-2)" "unprognostic (9.04e-3)" "prognostic unfavorable (2.84e-5)" "unprognostic (6.80e-3)" "prognostic unfavorable (4.41e-6)" "unprognostic (2.33e-1)" "unprognostic (1.45e-1)" "unprognostic (2.88e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.88e-8)" "prognostic unfavorable (3.27e-6)" "unprognostic (1.05e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (5.51e-4)" SERPINE2 "GDN, nexin, PI7, PN1, PNI" ENSG00000135919 "Serpin family E member 2" P07093 2 223975045-224039318 "Plasma proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein, Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "ovary: 284.1;placenta: 1054.7" "Cell type enhanced" "Detected in many" "Astrocytes: 221.1;Extravillous trophoblasts: 605.0;Granulosa cells: 395.3;Leydig cells: 405.7;Melanocytes: 216.4;Ovarian stromal cells: 442.9" "Cancer enriched" "Detected in all" 9 "melanoma: 271.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 13.0;naive CD8 T-cell: 6.9;NK-cell: 23.3" "Group enriched" "Detected in many" 15 "NK-cells: 23.3;T-cells: 13.0" "Cancer enriched" "Detected in all" 5 "skin cancer: 2214.3" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000277 Approved "Golgi apparatus" "Secreted in female reproductive system" "Developmental protein" NA NA 910000 "Cluster 24: Non-specific - Transcription" "Cluster 58: Placenta - Pregnancy" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 1 "Golgi apparatus" "HPA000277: " "unprognostic (1.73e-1)" "unprognostic (7.08e-3)" "unprognostic (8.49e-2)" "unprognostic (7.78e-3)" "unprognostic (2.57e-3)" "unprognostic (5.57e-2)" "unprognostic (1.49e-2)" "unprognostic (7.43e-3)" "unprognostic (4.41e-1)" "unprognostic (7.12e-2)" "unprognostic (7.56e-3)" "unprognostic (2.40e-1)" "unprognostic (1.97e-3)" "unprognostic (1.23e-2)" "unprognostic (1.31e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.48e-5)" SERPINE3 ENSG00000253309 "Serpin family E member 3" A8MV23 13 51335773-51364735 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 1.2;retina: 1.7" "Cell type enhanced" "Detected in some" "Astrocytes: 1.5;Early spermatids: 2.6;Excitatory neurons: 2.2;Inhibitory neurons: 1.9;Mesothelial cells: 4.3;Oligodendrocyte precursor cells: 2.4;Oligodendrocytes: 2.3;Spermatocytes: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA051904, HPA055804" Uncertain "Secreted in other tissues" "Enzyme inhibitor" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" "HPA051904: AB_2681659, HPA055804: AB_2682928" "unprognostic (1.60e-1)" "unprognostic (6.17e-2)" "unprognostic (9.66e-2)" "unprognostic (3.89e-2)" "unprognostic (5.52e-2)" "unprognostic (8.54e-3)" "unprognostic (2.67e-3)" "unprognostic (2.73e-1)" "unprognostic (1.87e-2)" "unprognostic (1.99e-3)" "unprognostic (1.70e-2)" "unprognostic (1.07e-1)" "unprognostic (3.94e-6)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (1.24e-1)" "unprognostic (3.31e-2)" SERPINF1 "EPC-1, PEDF, PIG35" ENSG00000132386 "Serpin family F member 1" P36955 17 1762029-1777565 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "choroid plexus: 4719.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 665.9;Cytotrophoblasts: 799.4;Fibroblasts: 881.9;Hepatocytes: 714.4;Leydig cells: 1843.9;Peritubular cells: 1051.8" "Cancer enhanced" "Detected in all" "liver cancer: 245.2" "Region enriched" "Detected in all" 20 "choroid plexus: 3985.5" "Immune cell enriched" "Detected in many" 18 "plasmacytoid DC: 1458.3" "Lineage enriched" "Detected in all" 121 "dendritic cells: 1458.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 156.0" "Adipose visceral - Macrophages, Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005825 Uncertain "Secreted to blood" "No annotated function" NA NA 9290000000 44000000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 3 "HPA005825: AB_1079921" "unprognostic (3.85e-1)" "prognostic favorable (5.49e-4)" "unprognostic (9.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.96e-2)" "unprognostic (2.09e-1)" "unprognostic (3.32e-3)" "unprognostic (2.33e-1)" "unprognostic (7.88e-2)" "unprognostic (5.92e-2)" "unprognostic (1.69e-1)" "unprognostic (4.18e-2)" "prognostic unfavorable (1.40e-8)" "unprognostic (2.11e-3)" "unprognostic (2.82e-1)" "unprognostic (4.53e-3)" "unprognostic (1.25e-3)" SERPINF2 "A2AP, AAP, ALPHA-2-PI, alpha2AP, API, PLI" ENSG00000167711 "Serpin family F member 2" P08697 17 1742836-1755265 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "liver: 1539.8" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 814.9" "Cancer enriched" "Detected in all" 6 "liver cancer: 450.6" "Region enriched" "Detected in all" 7 "choroid plexus: 21.0" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 44.8" "Lineage enriched" "Detected in many" 23 "dendritic cells: 44.8" "Group enriched" "Detected in many" 14 "Gastric cancer: 46.8;liver cancer: 36.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001885, HPA005943, CAB024863" Approved Approved "Golgi apparatus" "Secreted to blood" "Acute phase" NA NA 11900 61000000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 31: Liver - Plasma proteins" "Cluster 36: Choroid plexus - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "Golgi apparatus" "CAB024863: , HPA001885: AB_1079922, HPA005943: " "unprognostic (2.17e-3)" "unprognostic (2.56e-3)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (3.69e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (2.18e-1)" "unprognostic (1.09e-3)" "unprognostic (7.05e-2)" "unprognostic (2.81e-1)" "unprognostic (7.68e-3)" "unprognostic (2.93e-1)" SERPING1 "C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2" ENSG00000149131 "Serpin family G member 1" P05155 11 57597387-57619171 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Complement pathway, Fibrinolysis, Hemostasis, Immunity, Innate immunity" "Protease inhibitor, Serine protease inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2545.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 662.0;Ductal cells: 686.0;Fibroblasts: 846.6;Hepatocytes: 2176.6;Leydig cells: 740.9;Mesothelial cells: 1959.4" "Cancer enhanced" "Detected in all" "liver cancer: 609.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 65.5;plasmacytoid DC: 60.7" "Group enriched" "Detected in many" 231 "dendritic cells: 60.7;granulocytes: 65.5;monocytes: 25.7" "Cancer enhanced" "Detected in many" "liver cancer: 37.5;testis cancer: 38.7" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 255.7" "CAB026161, HPA048738" Supported "Secreted to blood" "Blood coagulation" NA NA 28000000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "CAB026161: , HPA048738: AB_2680505" "unprognostic (1.35e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (9.96e-4)" "unprognostic (4.26e-2)" "unprognostic (4.38e-2)" "unprognostic (2.32e-1)" "unprognostic (4.12e-3)" "unprognostic (2.13e-1)" "unprognostic (8.95e-2)" "prognostic favorable (8.03e-4)" "unprognostic (5.92e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.60e-2)" "unprognostic (4.14e-2)" "unprognostic (2.56e-1)" "unprognostic (1.17e-1)" SERPINH1 "CBP1, CBP2, HSP47, SERPINH2" ENSG00000149257 "Serpin family H member 1" P50454 11 75562056-75572783 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 277.2;Extravillous trophoblasts: 382.0;Fibroblasts: 270.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004441, HPA029198" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA Yes 920000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 27 "Endoplasmic reticulum" "CAB004441: AB_627757, HPA029198: AB_10601712" "unprognostic (3.80e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (5.93e-2)" "unprognostic (2.81e-3)" "unprognostic (3.25e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.39e-2)" "unprognostic (1.72e-3)" "unprognostic (2.35e-2)" "unprognostic (7.40e-2)" "unprognostic (1.57e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.22e-15)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" SERPINI1 PI12 ENSG00000163536 "Serpin family I member 1" Q99574 3 167735243-167825569 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 314.7;retina: 81.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 165.0;Excitatory neurons: 170.9;Inhibitory neurons: 220.0;Muller glia cells: 72.1;Oligodendrocytes: 162.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 47.8;thyroid cancer: 73.8" "Heart muscle - Smooth muscle cells, Kidney - Proximal tubular cells, Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001565, HPA056092" Enhanced Uncertain Cytosol "Secreted in brain" "Enzyme inhibitor" NA NA 750000 "Cluster 24: Non-specific - Transcription" "Cluster 33: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 25: Bipolar cells - Visual perception" Cytosol "HPA001565: AB_1079924, HPA056092: AB_2683036" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (4.09e-3)" "unprognostic (1.35e-1)" "unprognostic (6.97e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (4.25e-4)" "unprognostic (2.48e-1)" "unprognostic (2.61e-1)" "unprognostic (6.07e-3)" "unprognostic (2.18e-2)" "unprognostic (1.01e-1)" "unprognostic (1.58e-3)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (1.22e-1)" "unprognostic (1.11e-1)" SERPINI2 "MEPI, PI14, TSA2004" ENSG00000114204 "Serpin family I member 2" O75830 3 167441914-167478972 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 265 "pancreas: 1374.8" "Cell type enhanced" "Detected in some" "Astrocytes: 35.6;Ciliated cells: 10.7;Exocrine glandular cells: 45.3" "Cancer enriched" "Detected in some" 6 "pancreatic cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.2" "Kidney - Podocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 11.3" "Secreted to digestive system" "Enzyme inhibitor" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 5 "unprognostic (1.88e-2)" "unprognostic (2.23e-3)" "unprognostic (1.14e-1)" "unprognostic (5.27e-2)" "unprognostic (1.17e-2)" "unprognostic (1.29e-2)" "unprognostic (1.11e-2)" "unprognostic (2.04e-1)" "unprognostic (3.13e-1)" "unprognostic (1.76e-5)" "unprognostic (5.35e-2)" "unprognostic (4.16e-2)" SFN YWHAS ENSG00000175793 Stratifin P31947 1 26863149-26864456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2392.4;skin 1: 1181.2;vagina: 671.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 7039.2;Basal squamous epithelial cells: 1977.4;Squamous epithelial cells: 3788.2;Suprabasal keratinocytes: 12189.4" "Cancer enhanced" "Detected in all" "cervical cancer: 1510.8;head and neck cancer: 2526.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 5.9" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1337.8;head and neck cancer: 928.9" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 6.8" "CAB006268, HPA011105, CAB040552" Enhanced Supported Cytosol "Secreted in other tissues" "No annotated function" NA Yes 29000000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 39 Cytosol "CAB006268: AB_425459, CAB040552: , HPA011105: AB_1844339" "unprognostic (5.70e-2)" "unprognostic (1.26e-1)" "unprognostic (8.37e-2)" "prognostic favorable (1.92e-4)" "unprognostic (1.26e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.68e-5)" "unprognostic (1.71e-2)" "unprognostic (2.99e-1)" "unprognostic (3.96e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.83e-1)" "prognostic unfavorable (7.45e-6)" "unprognostic (7.90e-3)" "unprognostic (3.25e-1)" "unprognostic (8.12e-2)" "unprognostic (2.06e-2)" SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261962-41309473 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 668.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 747.8;Breast myoepithelial cells: 1177.7;Cardiomyocytes: 305.1;Fibroblasts: 269.9;Leydig cells: 595.4;Serous glandular cells: 490.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 19 "choroid plexus: 1106.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 243.9" "Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008116 Approved "Secreted in other tissues" "Developmental protein" NA No 1300000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "CAB008116: AB_2187070" "unprognostic (1.23e-3)" "unprognostic (7.01e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-1)" "unprognostic (7.13e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.79e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.67e-3)" "unprognostic (3.52e-3)" "unprognostic (4.74e-2)" "unprognostic (1.72e-2)" "unprognostic (1.75e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (3.12e-4)" SFRP2 "FRP-2, SARP1, SDF-5" ENSG00000145423 "Secreted frizzled related protein 2" Q96HF1 4 153780591-153789083 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 307.9;urinary bladder: 296.1" "Cell type enriched" "Detected in many" 7 "Fibroblasts: 713.7" "Cancer enhanced" "Detected in all" "pancreatic cancer: 370.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 25.0" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002652 Approved "Intermediate filaments" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 29: Forebrain - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "Intermediate filaments" "HPA002652: AB_2732394" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (7.21e-3)" "unprognostic (1.80e-2)" "unprognostic (2.73e-1)" "unprognostic (8.80e-3)" "unprognostic (5.71e-3)" "unprognostic (2.62e-2)" "unprognostic (2.79e-1)" "unprognostic (7.47e-3)" "unprognostic (1.44e-2)" "unprognostic (5.29e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (9.29e-3)" "unprognostic (4.72e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.39e-4)" SFRP4 "FRP-4, frpHE, FRZB-2" ENSG00000106483 "Secreted frizzled related protein 4" Q6FHJ7 7 37905932-38025695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 597.8;endometrium 1: 453.1" "Group enriched" "Detected in many" 5 "Endometrial stromal cells: 421.9;Fibroblasts: 386.7;Ovarian stromal cells: 148.2;Peritubular cells: 187.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 8.9;Gastric cancer: 17.3" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 70.5" "HPA009712, HPA050585" Enhanced "Secreted in female reproductive system" "Developmental protein" NA NA 2500000 "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 3 "HPA009712: AB_1856778, HPA050585: AB_2681183" "unprognostic (5.93e-2)" "unprognostic (5.84e-3)" "unprognostic (2.75e-2)" "unprognostic (1.58e-3)" "unprognostic (2.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.02e-2)" "unprognostic (2.60e-1)" "unprognostic (1.21e-1)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.36e-5)" "unprognostic (7.37e-3)" "unprognostic (1.61e-1)" "unprognostic (4.35e-3)" "unprognostic (1.89e-3)" SFRP5 SARP3 ENSG00000120057 "Secreted frizzled related protein 5" Q5T4F7 10 97766751-97771999 "Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "choroid plexus: 222.2;heart muscle: 76.1;pancreas: 138.7" "Group enriched" "Detected in some" 4 "Cholangiocytes: 230.8;Schwann cells: 119.8" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 30.4" "Region enriched" "Detected in all" 7 "choroid plexus: 203.7" "Immune cell enriched" "Detected in single" 4 "naive CD8 T-cell: 3.6" "Lineage enriched" "Detected in single" 4 "T-cells: 3.6" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.6;prostate cancer: 8.8" "Liver - Cholangiocyte, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "spinal cord: 159.2" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 18: Liver cancer - Metabolism" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "unprognostic (2.63e-4)" "unprognostic (3.03e-3)" "unprognostic (6.74e-2)" "unprognostic (3.43e-2)" "unprognostic (9.85e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" "unprognostic (3.19e-1)" "unprognostic (2.85e-1)" "unprognostic (8.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (4.51e-9)" "unprognostic (1.67e-2)" "unprognostic (1.57e-1)" "unprognostic (9.17e-2)" "unprognostic (1.62e-1)" SFTA2 "SFTPG, SP-G" ENSG00000196260 "Surfactant associated 2" Q6UW10 6 30931353-30955636 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 47.7;lung: 173.7" "Group enriched" "Detected in many" 10 "Alveolar cells type 1: 1168.2;Alveolar cells type 2: 1665.0" "Cancer enhanced" "Detected in many" "lung cancer: 121.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.1;breast cancer: 3.0;lung cancer: 2.5" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA "Cluster 57: Lung - Lung function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" "unprognostic (5.82e-2)" "unprognostic (1.16e-1)" "unprognostic (7.20e-3)" "unprognostic (6.64e-2)" "unprognostic (3.12e-1)" "unprognostic (1.34e-1)" "unprognostic (6.37e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (1.16e-1)" "unprognostic (3.96e-4)" "unprognostic (8.84e-2)" "unprognostic (2.36e-2)" "unprognostic (5.39e-3)" "unprognostic (7.95e-2)" SFTPA1 "COLEC4, SFTP1, SP-A, SP-A1" ENSG00000122852 "Surfactant protein A1" Q8IWL2 10 79610939-79615455 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1049 "lung: 6866.0" "Cell type enriched" "Detected in some" 23 "Alveolar cells type 2: 13843.8" "Cancer enriched" "Detected in some" 25 "lung cancer: 706.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 27 "plasmacytoid DC: 2.7" "Lineage enriched" "Detected in single" 27 "dendritic cells: 2.7" "Cancer enriched" "Detected in single" 7 "lung cancer: 6.4" "Lung - Alveolar cells type 2" "CAB016793, HPA042638, HPA045752, HPA049368" Supported "Secreted in other tissues" Other NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 57: Lung - Lung function" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 1 "CAB016793: , HPA042638: AB_2678095, HPA045752: AB_2679442, HPA049368: AB_2680731" "unprognostic (5.83e-4)" "unprognostic (1.17e-1)" "unprognostic (3.38e-2)" "unprognostic (4.24e-1)" "unprognostic (3.47e-2)" "unprognostic (9.09e-2)" SFTPA2 "COLEC5, SP-A2" ENSG00000185303 "Surfactant protein A2" Q8IWL1 10 79555852-79560407 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 405 "lung: 10463.2" "Cell type enriched" "Detected in some" 18 "Alveolar cells type 2: 17736.2" "Cancer enriched" "Detected in many" 21 "lung cancer: 863.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "lung cancer: 6.8;prostate cancer: 6.9" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells" "CAB002439, HPA042638, HPA045752, HPA049368" Enhanced "Secreted in other tissues" Other NA NA "Cluster 57: Lung - Lung function" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 2 "CAB002439: AB_564143, HPA042638: AB_2678095, HPA045752: AB_2679442, HPA049368: AB_2680731" "unprognostic (2.51e-1)" "unprognostic (4.87e-2)" "unprognostic (4.99e-2)" "unprognostic (4.38e-2)" "unprognostic (4.29e-2)" "unprognostic (1.05e-1)" "unprognostic (5.78e-2)" "unprognostic (5.08e-1)" "unprognostic (4.94e-2)" "unprognostic (1.68e-3)" "unprognostic (3.10e-1)" "unprognostic (3.56e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (4.69e-3)" SFTPB "SFTP3, SP-B" ENSG00000168878 "Surfactant protein B" P07988 2 85657314-85668741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 31 "lung: 3453.9" "Group enriched" "Detected in some" 14 "Alveolar cells type 1: 6026.1;Alveolar cells type 2: 12958.3" "Cancer enriched" "Detected in many" 5 "lung cancer: 1306.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "thyroid cancer: 19.2" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002440, HPA034820, HPA062148" Enhanced "Secreted in other tissues" Other NA NA 80000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 57: Lung - Lung function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 72: Alveolar cells - Lung function" "CAB002440: AB_564142, HPA034820: AB_2674347, HPA062148: AB_2684697" "unprognostic (6.46e-3)" "unprognostic (4.94e-2)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (2.25e-3)" "unprognostic (4.57e-3)" "unprognostic (8.57e-3)" "unprognostic (6.45e-3)" "unprognostic (1.13e-1)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (2.99e-6)" "unprognostic (2.37e-1)" "unprognostic (1.09e-1)" "unprognostic (7.90e-2)" "unprognostic (4.38e-2)" SFTPC "BRICD6, PSP-C, SFTP2, SMDP2, SP-C" ENSG00000168484 "Surfactant protein C" P11686 8 22156913-22164479 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 795 "lung: 17877.0" "Cell type enriched" "Detected in some" 27 "Alveolar cells type 2: 98114.0" "Cancer enriched" "Detected in some" 218 "lung cancer: 226.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Sarcoma: 1.5;skin cancer: 1.3" "Lung - Alveolar cells type 2, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010928 Enhanced "Secreted in other tissues" Other NA NA "Cluster 57: Lung - Lung function" "Cluster 11: White matter - Signal transduction" "Cluster 34: Testis cancer - Unknown function" "Cluster 72: Alveolar cells - Lung function" 26 "HPA010928: AB_1857425" "unprognostic (1.84e-1)" "unprognostic (1.96e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (2.97e-1)" "unprognostic (4.97e-2)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (1.32e-2)" SFTPD "COLEC7, SFTP4, SP-D" ENSG00000133661 "Surfactant protein D" P35247 10 79937467-79982614 "Predicted secreted proteins" "Gaseous exchange, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "lung: 492.1" "Cell type enriched" "Detected in many" 6 "Alveolar cells type 2: 1469.1" "Cancer enriched" "Detected in many" 16 "lung cancer: 106.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 10.0;non-classical monocyte: 36.5" "Lineage enriched" "Detected in many" 18 "monocytes: 36.5" "Low cancer specificity" "Detected in some" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB004578, HPA044582, HPA056768" Enhanced "Secreted in other tissues" Immunity NA NA 8200000 "Cluster 40: Monocytes - Innate immune response" "Cluster 57: Lung - Lung function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 72: Alveolar cells - Lung function" 1 "CAB004578: AB_628276, HPA044582: AB_2679004, HPA056768: AB_2683232" "unprognostic (3.81e-5)" "unprognostic (7.00e-2)" "unprognostic (1.19e-2)" "unprognostic (1.41e-2)" "unprognostic (4.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.66e-3)" "unprognostic (6.83e-2)" "unprognostic (3.85e-1)" "unprognostic (2.23e-1)" "unprognostic (5.29e-2)" "unprognostic (2.57e-1)" "unprognostic (4.70e-2)" "unprognostic (2.57e-2)" "unprognostic (2.38e-1)" "unprognostic (1.45e-1)" "unprognostic (8.86e-2)" SGCA "A2, adhalin, ADL, DMDA2, LGMD2D, SCARMD1" ENSG00000108823 "Sarcoglycan alpha" Q16586 17 50164214-50175928 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 146.2;skeletal muscle: 460.6;tongue: 208.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 76.5;Early spermatids: 115.6;Late spermatids: 671.7;Skeletal myocytes: 249.8" "Cancer enhanced" "Detected in many" "prostate cancer: 4.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "intermediate monocyte: 1.0;memory B-cell: 2.9;myeloid DC: 1.5;naive B-cell: 2.8;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 20 "B-cells: 2.9;dendritic cells: 1.5;monocytes: 1.4" "Cancer enriched" "Detected in single" 35 "Sarcoma: 23.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skin - Fibroblast_2, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007537 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 63: Late spermatids - Spermatogenesis" 6 "HPA007537: AB_1079944" "unprognostic (1.34e-1)" "unprognostic (2.30e-2)" "unprognostic (1.89e-3)" "unprognostic (1.25e-1)" "unprognostic (9.87e-2)" "unprognostic (2.43e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-2)" "unprognostic (1.15e-1)" "unprognostic (1.91e-1)" "unprognostic (7.01e-2)" "unprognostic (2.57e-1)" "unprognostic (2.07e-3)" "unprognostic (4.96e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-1)" "unprognostic (1.15e-2)" SGSH "HSS, MPS3A, SFMD" ENSG00000181523 "N-sulfoglucosamine sulfohydrolase" P51688 17 80206716-80220923 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023436, HPA023451" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Spleen - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 1 "HPA023436: AB_1856806, HPA023451: AB_1856807" "unprognostic (4.33e-2)" "unprognostic (4.03e-2)" "unprognostic (1.06e-2)" "unprognostic (4.01e-2)" "unprognostic (4.26e-3)" "unprognostic (1.39e-3)" "prognostic unfavorable (7.71e-4)" "prognostic favorable (2.72e-4)" "unprognostic (6.08e-2)" "unprognostic (3.65e-1)" "prognostic favorable (3.10e-4)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.42e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (7.50e-2)" "unprognostic (3.68e-2)" SHBG "ABP, MGC126834, MGC138391, TEBG" ENSG00000129214 "Sex hormone binding globulin" P04278 17 7613946-7633382 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 61.5" "Cell type enhanced" "Detected in some" "Early spermatids: 51.9;Late spermatids: 124.0;Proximal enterocytes: 28.6" "Cancer enriched" "Detected in some" 28 "liver cancer: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Secreted to blood" Transport NA NA 9100000000 "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 36: Late spermatids - Unknown function" "unprognostic (3.35e-3)" "unprognostic (6.47e-2)" "unprognostic (5.65e-2)" "unprognostic (2.35e-1)" "unprognostic (8.84e-2)" "unprognostic (3.08e-1)" "unprognostic (3.50e-1)" "unprognostic (2.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.32e-3)" "unprognostic (3.58e-3)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (7.83e-3)" "unprognostic (4.35e-1)" "unprognostic (5.50e-3)" "unprognostic (1.06e-1)" SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 52.9;Alveolar cells type 1: 21.5;Endothelial cells: 75.5;Kupffer cells: 23.4;Lymphatic endothelial cells: 44.2;Microglial cells: 25.0;Spermatocytes: 26.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037417 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" "No annotated function" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 11: Neuronal - Sensory perception" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Nucleoplasm Cytosol "HPA037417: AB_10672384" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (7.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (6.80e-3)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (3.10e-2)" "unprognostic (8.22e-2)" "unprognostic (4.04e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-2)" "unprognostic (7.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-3)" "unprognostic (1.33e-2)" SHH "HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS" ENSG00000164690 "Sonic hedgehog signaling molecule" Q15465 7 155799980-155812463 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Hydrolase, Protease, Transferase" "Disease variant, Holoprosencephaly, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 8.4;liver: 13.3;stomach 1: 10.2;urinary bladder: 15.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 10.8;Alveolar cells type 2: 9.9;Cholangiocytes: 15.3;Collecting duct cells: 7.8;Gastric mucus-secreting cells: 10.0;Glandular and luminal cells: 8.3;Hepatocytes: 17.7;Intestinal goblet cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 13.5" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" "Developmental protein" NA NA 5500000 "Cluster 83: Liver - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "unprognostic (7.17e-2)" "unprognostic (7.68e-3)" "unprognostic (6.70e-2)" "prognostic favorable (8.62e-5)" "unprognostic (1.59e-1)" "unprognostic (2.50e-2)" "unprognostic (2.39e-3)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.16e-2)" "unprognostic (3.47e-1)" "unprognostic (1.56e-1)" "unprognostic (1.77e-3)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (3.43e-2)" "unprognostic (2.66e-2)" SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 101.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 110.6;Proximal enterocytes: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" Enzyme NA NA 2200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favorable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favorable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" SIGLEC1 "CD169, dJ1009E24.1, FLJ00051, FLJ00055, FLJ00073, FLJ32150, sialoadhesin, SIGLEC-1, SN" ENSG00000088827 "Sialic acid binding Ig like lectin 1" Q9BZZ2 20 3686970-3712600 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 10 "Hofbauer cells: 76.4;Kupffer cells: 63.6;Macrophages: 44.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.5" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053457 Supported "Intracellular and membrane" "Cell adhesion" NA NA 260000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "HPA053457: AB_2682158" "unprognostic (2.05e-1)" "unprognostic (9.27e-3)" "unprognostic (3.83e-4)" "unprognostic (4.87e-3)" "unprognostic (3.40e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (6.98e-2)" "unprognostic (2.27e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (8.69e-5)" "unprognostic (8.71e-2)" "prognostic unfavorable (4.36e-4)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 37.5" "Cell type enhanced" "Detected in some" "B-cells: 31.9;Kupffer cells: 96.7;Macrophages: 64.4;monocytes: 184.9;Schwann cells: 25.0" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 767.4;intermediate monocyte: 252.2;non-classical monocyte: 542.7" "Group enriched" "Detected in many" 16 "granulocytes: 767.4;monocytes: 542.7" "Group enriched" "Detected in many" 6 "Leukemia: 10.6;lymphoma: 31.2" "Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" Immunity NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Macrophages - Innate immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" SIGLEC6 "CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6" ENSG00000105492 "Sialic acid binding Ig like lectin 6" O43699 19 51517819-51531856 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "placenta: 103.1" "Group enriched" "Detected in some" 12 "Cytotrophoblasts: 172.9;granulocytes: 226.4;Syncytiotrophoblasts: 322.5" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 7.2;plasmacytoid DC: 11.0" "Group enriched" "Detected in many" 9 "B-cells: 7.2;dendritic cells: 11.0;granulocytes: 4.9" "Group enriched" "Detected in some" 5 "Bladder cancer: 7.8;colorectal cancer: 11.8;Leukemia: 25.0" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells, Skin - Mast cells" "Low region specificity" "Detected in some" "HPA008945, HPA009084, HPA018198" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" "Cell adhesion" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 58: Placenta - Pregnancy" "Cluster 48: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 "Plasma membrane, Cytosol" "HPA008945: , HPA009084: AB_1079967, HPA018198: AB_1856868" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (9.31e-3)" "unprognostic (8.46e-4)" "unprognostic (2.91e-1)" "unprognostic (2.02e-2)" "unprognostic (2.64e-1)" "unprognostic (8.96e-2)" "unprognostic (2.03e-1)" "unprognostic (6.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.15e-2)" "unprognostic (4.42e-2)" "unprognostic (3.28e-2)" "unprognostic (5.57e-3)" SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.7" "Group enriched" "Detected in some" 5 "Hofbauer cells: 36.2;Kupffer cells: 60.6;Macrophages: 29.8;NK-cells: 38.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.7" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 16 "Leukemia: 3.5;Myeloma: 4.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "HPA075513, CAB080396" Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 2600000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "Plasma membrane" Vesicles "CAB080396: , HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" SIL1 "BAP, MSS, ULG5" ENSG00000120725 "SIL1 nucleotide exchange factor" Q9H173 5 138946724-139293557 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011949 Enhanced "Intracellular and membrane" Transport NA NA 710000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 3 "HPA011949: AB_1856875" "unprognostic (1.06e-1)" "unprognostic (9.01e-2)" "unprognostic (2.04e-1)" "prognostic favorable (4.34e-4)" "prognostic unfavorable (4.27e-4)" "unprognostic (9.12e-3)" "unprognostic (3.60e-1)" "unprognostic (2.45e-1)" "unprognostic (1.33e-1)" "unprognostic (6.91e-2)" "unprognostic (2.31e-2)" "unprognostic (9.46e-2)" "unprognostic (3.21e-3)" "unprognostic (1.59e-1)" "unprognostic (1.65e-1)" "unprognostic (6.79e-2)" "unprognostic (1.22e-2)" SIRPD "dJ576H24.4, PTPNS1L2" ENSG00000125900 "Signal regulatory protein delta" Q9H106 20 1534251-1557705 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 56.2" "Group enriched" "Detected in some" 61 "Early spermatids: 276.8;Late spermatids: 490.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "neutrophil: 37.4" "Group enriched" "Detected in many" 4 "granulocytes: 37.4;monocytes: 21.1" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.2" "Adipose subcutaneous - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA042663 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 44: Testis - Spermatogenesis" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 11: Late spermatids - Unknown function" "HPA042663: AB_2678102" "unprognostic (4.91e-2)" "unprognostic (1.51e-2)" "unprognostic (3.01e-2)" "unprognostic (4.47e-1)" "unprognostic (2.49e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-2)" "unprognostic (2.79e-1)" "unprognostic (3.66e-8)" "unprognostic (2.14e-1)" "unprognostic (3.32e-2)" "unprognostic (9.57e-3)" "unprognostic (2.44e-2)" SLAMF1 "CD150, SLAM" ENSG00000117090 "Signaling lymphocytic activation molecule family member 1" Q13291 1 160608106-160647044 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Host-virus interaction, Immunity, Innate immunity, Phagocytosis" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 61.9" "Group enriched" "Detected in some" 4 "B-cells: 25.3;Plasma cells: 74.3;T-cells: 40.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 51.2;T-reg: 49.0" "Group enriched" "Detected in many" 16 "B-cells: 17.9;T-cells: 51.2" "Cancer enhanced" "Detected in some" "Leukemia: 14.5;lymphoma: 35.8" "Adipose subcutaneous - T-cells, Liver - T-cells, Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002438, HPA069319" Enhanced "Secreted to blood" Receptor NA NA 350000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" 2 "CAB002438: AB_564011, HPA069319: AB_2732129" "unprognostic (2.99e-3)" "unprognostic (3.33e-4)" "unprognostic (2.93e-4)" "unprognostic (1.38e-4)" "unprognostic (5.87e-2)" "unprognostic (6.06e-5)" "unprognostic (1.64e-2)" "unprognostic (1.70e-3)" "unprognostic (1.69e-2)" "unprognostic (2.74e-4)" "unprognostic (6.12e-2)" "unprognostic (3.58e-1)" "unprognostic (1.24e-7)" "unprognostic (2.46e-1)" "unprognostic (8.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.18e-2)" SLC25A14 "BMCP1, UCP5" ENSG00000102078 "Solute carrier family 25 member 14" O95258 X 130339888-130373361 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 34.6;Spermatocytes: 31.8;Spermatogonia: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060316 Approved Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 42: Ciliated cells - Cilium assembly" Mitochondria "HPA060316: AB_2684251" "unprognostic (1.65e-2)" "prognostic favorable (1.72e-5)" "unprognostic (1.82e-1)" "unprognostic (2.74e-1)" "unprognostic (1.27e-1)" "unprognostic (1.16e-1)" "unprognostic (3.36e-3)" "unprognostic (8.92e-3)" "unprognostic (3.52e-2)" "unprognostic (2.95e-3)" "prognostic favorable (1.78e-4)" "unprognostic (2.18e-2)" "prognostic unfavorable (5.52e-6)" "unprognostic (6.05e-2)" "unprognostic (1.12e-1)" "unprognostic (6.92e-2)" "prognostic favorable (1.39e-5)" SLC25A25 "KIAA1896, MCSC, PCSCL" ENSG00000148339 "Solute carrier family 25 member 25" Q6KCM7 9 128068201-128109245 "Predicted intracellular proteins, Transporters" "Antiport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 133.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020381 Uncertain Supported Vesicles,Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 83: Liver - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 37: Glandular & Luminal cells - Unknown function" "Vesicles, Mitochondria" "HPA020381: AB_1857037" "unprognostic (4.62e-2)" "unprognostic (2.66e-2)" "unprognostic (2.56e-2)" "unprognostic (1.59e-1)" "unprognostic (2.89e-1)" "unprognostic (1.40e-1)" "prognostic favorable (1.01e-4)" "unprognostic (1.20e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (4.96e-2)" "unprognostic (3.70e-2)" "prognostic favorable (4.65e-6)" "unprognostic (1.21e-1)" "unprognostic (1.05e-2)" "unprognostic (1.66e-3)" "unprognostic (1.42e-2)" SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 148.4" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 942.4;Excitatory neurons: 1224.1;Inhibitory neurons: 602.1;Microglial cells: 548.4;Oligodendrocyte precursor cells: 706.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 39.9" "Group enriched" "Detected in many" 6 "granulocytes: 39.9;monocytes: 12.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Intercalated cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" 2 "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-2)" "unprognostic (7.57e-6)" "unprognostic (1.56e-1)" "unprognostic (3.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (7.04e-3)" "unprognostic (3.93e-2)" "unprognostic (5.46e-2)" "unprognostic (6.77e-2)" SLIT1 "MEGF4, SLIL1, Slit-1, SLIT3" ENSG00000187122 "Slit guidance ligand 1" O75093 10 96998038-97185959 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 33.9;pituitary gland: 13.1" "Cell type enhanced" "Detected in some" "Early spermatids: 13.4;Excitatory neurons: 92.9;Inhibitory neurons: 33.2;Late spermatids: 28.8;Oligodendrocyte precursor cells: 23.6" "Group enriched" "Detected in many" 4 "glioma: 9.2;thyroid cancer: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 11.1;thyroid cancer: 8.6" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006879 Approved "Plasma membrane" "Secreted in brain" "Developmental protein" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 34: Neurons - Neuronal signaling" 8 "Plasma membrane" "HPA006879: AB_1078197" "unprognostic (2.72e-1)" "unprognostic (2.25e-2)" "unprognostic (5.67e-3)" "unprognostic (1.43e-5)" "unprognostic (8.40e-2)" "unprognostic (2.60e-3)" "unprognostic (4.57e-2)" "unprognostic (1.81e-2)" "unprognostic (3.53e-1)" "unprognostic (6.06e-2)" "unprognostic (2.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.66e-1)" "unprognostic (2.18e-1)" "unprognostic (1.21e-1)" "unprognostic (4.39e-3)" SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 248.8;Inhibitory neurons: 524.8;Oligodendrocytes: 147.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" "Developmental protein" NA NA 77000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 1 "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 195.4;Fibroblasts: 114.4;Mesothelial cells: 47.4;Smooth muscle cells: 114.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cancer enhanced" "Detected in many" "Neuroblastoma: 66.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" SLITRK1 "KIAA1910, LRRC12" ENSG00000178235 "SLIT and NTRK like family member 1" Q96PX8 13 83877205-83882474 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 14.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 20.1;Excitatory neurons: 17.8;Inhibitory neurons: 13.4;Oligodendrocyte precursor cells: 23.6;Oligodendrocytes: 13.3" "Cancer enriched" "Detected in single" 8 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074835 Enhanced "Secreted in brain" "No annotated function" NA NA 330000 "Cluster 33: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 25: Bipolar cells - Visual perception" 1 "HPA074835: " "unprognostic (2.29e-1)" "unprognostic (4.32e-1)" "unprognostic (4.71e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-2)" "unprognostic (7.95e-2)" SLPI "ALK1, ALP, BLPI, HUSI, HUSI-I, WAP4, WFDC4" ENSG00000124107 "Secretory leukocyte peptidase inhibitor" P03973 20 45252239-45254564 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 26901.3;salivary gland: 13729.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 7399.9;Basal respiratory cells: 20685.7;Club cells: 18592.5;Ionocytes: 25231.1;Mucus glandular cells: 11091.7;Serous glandular cells: 7851.0" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 7 "choroid plexus: 50.1;thalamus: 14.3" "Immune cell enriched" "Detected in some" 80 "neutrophil: 323.6" "Lineage enriched" "Detected in many" 80 "granulocytes: 323.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 652.3" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002303, HPA027774" Enhanced Approved "Golgi apparatus" "Secreted to blood" Immunity NA NA 26400000 9600000 "Cluster 4: Neutrophils - Degranulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 12 "Golgi apparatus" "CAB002303: AB_564008, HPA027774: AB_10602405" "unprognostic (2.31e-2)" "unprognostic (3.07e-1)" "unprognostic (3.10e-2)" "unprognostic (2.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.16e-2)" "unprognostic (9.98e-2)" "unprognostic (2.90e-1)" "unprognostic (3.23e-1)" "unprognostic (1.83e-3)" "unprognostic (4.01e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (6.91e-5)" "unprognostic (1.53e-1)" "unprognostic (2.15e-1)" "unprognostic (8.81e-2)" "unprognostic (8.31e-2)" SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1010.0;skin 1: 831.0" "Cell type enriched" "Detected in some" 12 "Suprabasal keratinocytes: 2355.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 66.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 1.8;Esophageal cancer: 1.7;head and neck cancer: 2.5" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" Cytokine NA NA 7700000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA050967: AB_2681293" "unprognostic (1.22e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (7.32e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-4)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" SLURP2 ENSG00000283992 "Secreted LY6/PLAUR domain containing 2" P0DP57 8 142764338-142769828 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 846.5;skin 1: 323.4;vagina: 213.2" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 7.8;Ionocytes: 8.1;Squamous epithelial cells: 27.7;Suprabasal keratinocytes: 27.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Esophageal cancer: 4.2;head and neck cancer: 12.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells" "Secreted in other tissues" "No annotated function" NA NA 3100000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" SMIM20 "C4orf52, MITRAC7, PNX" ENSG00000250317 "Small integral membrane protein 20" Q8N5G0 4 25861830-25929813 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016552 Approved Approved Nucleoplasm,Nucleoli,Cytosol "Secreted to blood" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" Nucleoli "HPA016552: AB_1859536" "unprognostic (1.18e-1)" "unprognostic (3.73e-2)" "unprognostic (1.78e-1)" "unprognostic (6.52e-3)" "unprognostic (1.55e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.46e-1)" "unprognostic (1.02e-1)" "unprognostic (5.42e-2)" "unprognostic (2.86e-1)" "prognostic favorable (8.97e-5)" "unprognostic (5.51e-2)" "unprognostic (5.84e-2)" "unprognostic (1.53e-1)" "unprognostic (5.12e-3)" SMIM31 "h.EPR, LINC01207" ENSG00000248771 "Small integral membrane protein 31" A0A1B0GVY4 4 164754064-164803795 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 7.6;intestine: 23.9;prostate: 10.6" "Cell type enhanced" "Detected in some" "Club cells: 38.2;Distal enterocytes: 75.8;Exocrine glandular cells: 45.8;Intestinal goblet cells: 89.1;Paneth cells: 36.1;Prostatic glandular cells: 53.1;Proximal enterocytes: 124.0" "Cancer enhanced" "Detected in many" "prostate cancer: 8.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.1;Gastric cancer: 6.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted - unknown location" "No annotated function" NA NA "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "unprognostic (2.84e-1)" "unprognostic (1.18e-1)" "unprognostic (2.47e-2)" "unprognostic (1.87e-4)" "unprognostic (2.95e-2)" "unprognostic (1.78e-1)" "unprognostic (4.17e-2)" "unprognostic (4.82e-1)" "unprognostic (9.47e-2)" "unprognostic (5.63e-3)" SMIM7 "C19orf42, MGC2747" ENSG00000214046 "Small integral membrane protein 7" Q9BQ49 19 16630751-16660442 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043127 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "HPA043127: AB_10806378" "unprognostic (6.61e-2)" "unprognostic (1.61e-2)" "unprognostic (1.90e-1)" "unprognostic (3.71e-2)" "unprognostic (2.52e-1)" "unprognostic (2.28e-1)" "unprognostic (9.65e-2)" "unprognostic (1.79e-2)" "unprognostic (6.60e-3)" "unprognostic (1.90e-1)" "unprognostic (2.75e-1)" "unprognostic (1.76e-3)" "unprognostic (8.29e-3)" "unprognostic (2.94e-1)" "unprognostic (2.29e-1)" "unprognostic (8.38e-2)" "unprognostic (7.64e-2)" SMOC1 ENSG00000198732 "SPARC related modular calcium binding 1" Q9H4F8 14 69854131-70032366 "Disease related genes, Human disease related genes, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.8;liver: 66.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 82.2;Oligodendrocyte precursor cells: 349.5;Oligodendrocytes: 75.4;Peritubular cells: 132.2" "Cancer enhanced" "Detected in many" "glioma: 27.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cancer enhanced" "Detected in many" "cervical cancer: 36.1" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004153, CAB034427" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" "Developmental protein" NA NA 140000 "Cluster 33: Brain - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 76: Oligodendrocyte precursor - Unknown function" 3 "Plasma membrane" "CAB034427: AB_2193382, HPA004153: AB_1080035" "unprognostic (3.31e-1)" "unprognostic (2.17e-3)" "unprognostic (8.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.75e-3)" "unprognostic (2.09e-3)" "unprognostic (4.76e-2)" "unprognostic (2.80e-2)" "unprognostic (5.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.09e-2)" "unprognostic (3.92e-1)" "unprognostic (2.57e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" SMOC2 SMAP2 ENSG00000112562 "SPARC related modular calcium binding 2" Q9H3U7 6 168441151-168673445 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 186.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 141.8;Leydig cells: 318.3;Peritubular cells: 755.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 76.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.0" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Pancreas - Fibroblasts, Skeletal muscle - Fibroblasts" "Region enhanced" "Detected in many" "hippocampal formation: 25.7" "Region enhanced" "Detected in some" "spinal cord: 2.3" "Secreted to extracellular matrix" "No annotated function" NA NA 120000 "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 70: DU4475 - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 1 "unprognostic (3.23e-1)" "unprognostic (5.29e-2)" "unprognostic (3.70e-2)" "unprognostic (1.53e-2)" "unprognostic (2.43e-2)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (4.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.16e-6)" "unprognostic (3.50e-2)" "unprognostic (2.68e-1)" "unprognostic (6.35e-2)" "unprognostic (6.20e-3)" SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390440-6394998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 92.2;Late spermatids: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 2700000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 5: Enterocytes - Absorption" 1 "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (6.99e-2)" "unprognostic (2.28e-3)" "prognostic unfavorable (7.72e-5)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (4.90e-2)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.47e-4)" "unprognostic (4.35e-2)" "prognostic favorable (4.57e-6)" "unprognostic (4.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 151.1;Distal enterocytes: 169.7;Proximal enterocytes: 334.3;Syncytiotrophoblasts: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 81.1" "Lineage enriched" "Detected in many" 11 "granulocytes: 81.1" "Cancer enhanced" "Detected in all" "prostate cancer: 39.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" Enzyme No No 26000000 "Cluster 32: Basophils - Transcription" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 5: Enterocytes - Absorption" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" SMPDL3B ASML3B ENSG00000130768 "Sphingomyelin phosphodiesterase acid like 3B" Q92485 1 27935000-27959157 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.4;pancreas: 47.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 36.2;Distal enterocytes: 50.4;Paneth cells: 55.2;Proximal enterocytes: 37.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.3;myeloid DC: 1.3;neutrophil: 1.7" "Group enriched" "Detected in many" 7 "dendritic cells: 1.3;granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA030561 Approved "Golgi apparatus,Cytosol" "Secreted to blood" Immunity NA NA 400000 "Cluster 22: Eosinophils - Transcription" "Cluster 48: Stomach - Proteolysis" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" Cytosol "Golgi apparatus" "HPA030561: AB_10604095" "unprognostic (1.22e-2)" "unprognostic (4.45e-1)" "unprognostic (4.58e-3)" "unprognostic (3.83e-2)" "unprognostic (3.35e-3)" "unprognostic (2.96e-2)" "unprognostic (1.50e-1)" "unprognostic (2.68e-1)" "unprognostic (3.95e-1)" "unprognostic (6.02e-2)" "unprognostic (1.64e-1)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.48e-1)" "unprognostic (4.40e-2)" "unprognostic (3.09e-3)" SMR3A "PBI, PRL5, PROL5" ENSG00000109208 "Submaxillary gland androgen regulated protein 3A" Q99954 4 70360760-70367158 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "salivary gland: 58.0" "Group enriched" "Detected in some" 33 "Club cells: 2.3;Serous glandular cells: 8.5" "Cancer enhanced" "Detected in some" "breast cancer: 0.7;liver cancer: 0.5" "Region enhanced" "Detected in single" "midbrain: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044567 Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 75: Serous glandular cells - Salivary secretion" 3 "HPA044567: AB_10796114" "unprognostic (2.06e-1)" SMR3B "P-B, PRL3, PROL3" ENSG00000171201 "Submaxillary gland androgen regulated protein 3B" P02814 4 70370093-70390244 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 948 "salivary gland: 210537.1" "Cell type enriched" "Detected in some" 46 "Serous glandular cells: 40411.5" "Cancer enriched" "Detected in some" 22 "breast cancer: 32.5" "Region enhanced" "Detected in single" "midbrain: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "thyroid cancer: 44.3" "Testis - Late spermatids" "Secreted to digestive system" "No annotated function" NA NA 1900000 "Cluster 38: Salivary gland - Salivary secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 75: Serous glandular cells - Salivary secretion" 3 "unprognostic (3.72e-1)" SNCA "NACP, PARK1, PARK4, PD1" ENSG00000145335 "Synuclein alpha" P37840 4 89700345-89838315 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Alzheimer disease, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "bone marrow: 269.6;brain: 272.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 163.5;Erythroid cells: 547.2;Excitatory neurons: 243.0;Melanocytes: 448.4;Oligodendrocytes: 181.8" "Cancer enriched" "Detected in many" 8 "melanoma: 37.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 103.2" "Group enriched" "Detected in all" 4 "dendritic cells: 103.2;granulocytes: 51.5;monocytes: 67.2" "Cancer enhanced" "Detected in many" "skin cancer: 309.1" "Colon - Enteric glia cells, Liver - Erythroid cells, Lung - Fibroblast_1, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005459, CAB010877" Enhanced "Intracellular and membrane" "No annotated function" NA NA 28000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 1: Erythroid cells - Oxygen transport" 124 "CAB010877: AB_261518, HPA005459: AB_2667324" "unprognostic (4.80e-2)" "unprognostic (1.52e-1)" "unprognostic (8.13e-2)" "unprognostic (1.05e-3)" "unprognostic (2.65e-2)" "unprognostic (1.54e-2)" "unprognostic (1.78e-2)" "unprognostic (3.44e-2)" "unprognostic (1.73e-2)" "unprognostic (3.85e-3)" "unprognostic (1.01e-3)" "unprognostic (2.09e-2)" "unprognostic (1.57e-1)" "unprognostic (2.51e-3)" "unprognostic (1.68e-1)" "unprognostic (3.93e-4)" "unprognostic (7.48e-3)" SNED1 "FLJ00133, Snep, SST3" ENSG00000162804 "Sushi, nidogen and EGF like domains 1" Q8TER0 2 240998618-241095568 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 90.1;Excitatory neurons: 83.1;Fibroblasts: 37.1;Inhibitory neurons: 31.1;Leydig cells: 91.5;Microglial cells: 74.3;Peritubular cells: 66.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036414, HPA036415" Uncertain "Secreted to blood" "No annotated function" NA NA 27000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 66: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 34: Neurons - Neuronal signaling" "HPA036414: AB_10960852, HPA036415: AB_10964128" "unprognostic (1.41e-1)" "unprognostic (3.92e-2)" "unprognostic (1.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.57e-3)" "unprognostic (4.62e-2)" "unprognostic (7.77e-4)" "unprognostic (3.49e-2)" "unprognostic (4.96e-1)" "unprognostic (7.85e-3)" "unprognostic (3.42e-2)" "unprognostic (2.06e-2)" "unprognostic (2.80e-2)" "unprognostic (1.16e-1)" "unprognostic (3.72e-1)" "unprognostic (5.51e-3)" "unprognostic (4.95e-3)" SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 84.5;skin 1: 31.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 393.3;Breast myoepithelial cells: 338.2;Distal enterocytes: 121.1;Hepatocytes: 113.3;Intestinal goblet cells: 129.9;Melanocytes: 211.3;Muller glia cells: 101.1;Undifferentiated cells: 107.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 2.5" "Lineage enriched" "Detected in single" 19 "granulocytes: 2.5" "Cancer enhanced" "Detected in many" "breast cancer: 7.9" "Breast - Breast glandular cells (progenitors), Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" "No annotated function" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 22: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 20 "Nucleoplasm, Nucleoli" "HPA052824: AB_2681964" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-1)" "unprognostic (4.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (4.30e-7)" "unprognostic (1.83e-3)" "unprognostic (8.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.33e-2)" SNTB1 "59-DAP, A1B, BSYN2, SNT2, SNT2B1, TIP-43" ENSG00000172164 "Syntrophin beta 1" Q13884 8 120535745-120813273 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 86.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 37.8;Astrocytes: 66.6;Hepatocytes: 61.5;Microglial cells: 43.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 87.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024659 Uncertain "Intracellular and membrane" Other NA NA 25000 "Cluster 41: Basophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 3: Choroid plexus - Cilium" "Cluster 32: Non-specific - Cell proliferation" "Cluster 58: Macrophages - Innate immune response" 3 "HPA024659: AB_1857713" "unprognostic (1.32e-1)" "unprognostic (2.77e-2)" "unprognostic (6.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (6.41e-3)" "unprognostic (2.07e-1)" "unprognostic (3.88e-1)" "unprognostic (1.31e-1)" "unprognostic (4.72e-1)" "unprognostic (2.00e-2)" "unprognostic (5.08e-2)" "unprognostic (5.88e-2)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187147-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 146.4;Lymphatic endothelial cells: 147.9;Muller glia cells: 180.6;Rod photoreceptor cells: 134.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" Other NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 34: Neurons - Neuronal signaling" 4 "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA001394: AB_1080170" "unprognostic (4.86e-1)" "unprognostic (3.26e-2)" "unprognostic (2.77e-2)" "unprognostic (8.07e-3)" "unprognostic (6.46e-2)" "unprognostic (9.68e-2)" "unprognostic (1.89e-2)" "unprognostic (5.50e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.71e-2)" "unprognostic (7.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.88e-1)" SOD3 EC-SOD ENSG00000109610 "Superoxide dismutase 3" P08294 4 24789912-24800842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Antioxidant, Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "choroid plexus: 1089.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 382.7;Leydig cells: 396.6;Peritubular cells: 336.5;Schwann cells: 266.5;Smooth muscle cells: 498.8;Syncytiotrophoblasts: 224.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 10 "choroid plexus: 887.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042110 Supported "Secreted to blood" Enzyme NA NA 50400000 510000000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 5 "HPA042110: AB_2677850" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (8.80e-2)" "unprognostic (3.32e-2)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (4.98e-2)" "unprognostic (3.68e-1)" "unprognostic (2.39e-1)" "unprognostic (3.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.80e-2)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.45e-2)" SOGA1 "C20orf117, dJ132F21.1, FLJ44670, KIAA0889, SOGA" ENSG00000149639 "Suppressor of glucose, autophagy associated 1" O94964 20 36777447-36863538 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 70.7" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 51.4;Oligodendrocytes: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043992 Approved Approved Nucleoli,Cytosol "Secreted to blood" "No annotated function" NA Yes "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 12: Squamous epithelial cells - Keratinization" "Nucleoli, Cytosol" "HPA043992: AB_2678762" "unprognostic (2.34e-2)" "unprognostic (1.35e-1)" "unprognostic (6.58e-2)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.48e-1)" "unprognostic (2.27e-3)" "unprognostic (1.37e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.28e-5)" "unprognostic (1.09e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (4.49e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (4.45e-3)" SORL1 "C11orf32, gp250, LR11, LRP9, SorLA, SorLA-1" ENSG00000137642 "Sortilin related receptor 1" Q92673 11 121452314-121633763 "Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Transport" Receptor "Alzheimer disease, Amyloidosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 239.0;Microglial cells: 386.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 126.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 126.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Liver - Hepatocytes, Lung - Neutrophil_2, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011500, HPA031321" Uncertain "Secreted to blood" Receptor NA NA 79000 "Cluster 21: Neutrophils - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Neutrophils - Degranulation" 18 "CAB011500: AB_443414, HPA031321: AB_2673826" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.08e-2)" "unprognostic (9.53e-2)" "unprognostic (3.06e-1)" "unprognostic (1.18e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-3)" "unprognostic (1.74e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.80e-7)" "unprognostic (2.48e-1)" "unprognostic (1.87e-1)" "unprognostic (5.07e-2)" "unprognostic (1.21e-2)" SOST "DAND6, VBCH" ENSG00000167941 Sclerostin Q9BQB4 17 43753738-43758791 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" Heparin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "kidney: 13.0" "Group enriched" "Detected in some" 5 "B-cells: 1.6;Cholangiocytes: 1.9;Collecting duct cells: 5.8;Pancreatic endocrine cells: 1.7" "Cancer enhanced" "Detected in some" "lung cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 12.3;Rhabdoid: 19.6" "Group enriched" "Detected in some" 11 "basal ganglia: 1.7;cerebellum: 1.0" "Not detected" "Not detected" "Secreted to extracellular matrix" Other NA NA 16000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 7: Liver cancer - Metabolism" "Cluster 73: B-cells - B-cell function" 4 "unprognostic (1.26e-1)" "unprognostic (4.06e-2)" "unprognostic (6.57e-2)" "unprognostic (2.55e-3)" "unprognostic (3.37e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-1)" "unprognostic (8.35e-2)" "unprognostic (1.38e-2)" "unprognostic (1.20e-1)" "unprognostic (8.92e-2)" "unprognostic (1.56e-1)" "unprognostic (7.90e-2)" SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 240.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 66.3;Early spermatids: 23.7;Gastric mucus-secreting cells: 61.9;Melanocytes: 42.9;Proximal tubular cells: 23.2" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Region enriched" "Detected in all" 27 "choroid plexus: 247.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" Other NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" SPACA3 "ALLP17, CT54, LYC3, LYZL3, SLLP1" ENSG00000141316 "Sperm acrosome associated 3" Q8IXA5 17 32970376-32997877 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 121.8" "Group enriched" "Detected in some" 99 "Early spermatids: 1378.1;Late spermatids: 1100.1" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 5 "B-cells: 1.2" "Cancer enriched" "Detected in single" 11 "Myeloma: 8.3" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA023633 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 21: Early spermatids - Spermatogenesis" 1 "HPA023633: AB_1857407" "unprognostic (6.48e-2)" "unprognostic (2.83e-1)" "unprognostic (1.30e-1)" "unprognostic (7.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.31e-2)" "unprognostic (3.37e-1)" "unprognostic (5.91e-2)" "unprognostic (1.68e-1)" "unprognostic (5.70e-4)" "unprognostic (3.86e-2)" "unprognostic (1.79e-1)" "unprognostic (4.63e-1)" SPACA5 "dJ54B20.3, LYC5, LYZL5, PNPK6288, SLLP2, UNQ6288" ENSG00000171489 "Sperm acrosome associated 5" Q96QH8 X 48004336-48009733 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 13.7" "Cell type enhanced" "Detected in single" "Early spermatids: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Sarcoma: 1.7" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" Enzyme NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 18: Early spermatids - Unknown function" "HPA044747: AB_2679071, HPA047149: AB_2679955" SPACA5B LYZL5B ENSG00000171478 "Sperm acrosome associated 5B" Q96QH8 X 48130626-48132620 "Enzymes, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 62 "testis: 23.2" "Cell type enriched" "Detected in single" 5 "Early spermatids: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044747, HPA047149" Supported "Secreted in male reproductive system" Enzyme NA NA "Cluster 10: Testis - Spermatid development" "Cluster 54: Non-specific - Transcription" "Cluster 13: Spermatids - Transcription" "HPA044747: AB_2679071, HPA047149: AB_2679955" SPACA7 C13orf28 ENSG00000153498 "Sperm acrosome associated 7" Q96KW9 13 112376355-112434689 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 150 "testis: 81.7" "Group enriched" "Detected in some" 29 "Early spermatids: 1215.1;Late spermatids: 966.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" HPA048349 Enhanced "Secreted in male reproductive system" Other NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 10: Testis - Spermatid development" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 11: Late spermatids - Unknown function" "HPA048349: AB_2732548" "unprognostic (3.97e-2)" SPAG11A "EDDM2A, HE2" ENSG00000178287 "Sperm associated antigen 11A" Q6PDA7 8 7847876-7868867 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11473 "epididymis: 4639.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 64 "Uterine cancer: 6.4" "HPA023842, HPA057479" Supported Approved "Golgi apparatus" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Golgi apparatus" "HPA023842: AB_2732429, HPA057479: " SPAG11B "EDDM2B, EP2, EP2C, EP2D, HE2" ENSG00000164871 "Sperm associated antigen 11B" Q08648 8 7442684-7463674 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 3177 "epididymis: 1228.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 47 "Uterine cancer: 6.9" "HPA023842, HPA057479" Supported Approved "Golgi apparatus" "Secreted in male reproductive system" Defense NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "Golgi apparatus" "HPA023842: AB_2732429, HPA057479: " SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2105.6" "Cell type enhanced" "Detected in many" "Adipocytes: 681.1;Endometrial stromal cells: 1191.5;Endothelial cells: 596.8;Fibroblasts: 1099.9;Peritubular cells: 1088.4;Schwann cells: 907.7;Sertoli cells: 1387.1;Smooth muscle cells: 815.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.5" "Group enriched" "Detected in many" 7 "granulocytes: 24.5;monocytes: 8.7" "Cancer enhanced" "Detected in all" "Brain cancer: 2731.8" "Colon - Enteric glia cells, Prostate - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" "No annotated function" NA NA 8300000 130000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 1 Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" SPARCL1 MAST9 ENSG00000152583 "SPARC like 1" Q14515 4 87473335-87531061 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 4462.2;Endothelial cells: 2854.8;Fibroblasts: 1668.5;Peritubular cells: 2456.1;Sertoli cells: 1977.2;Smooth muscle cells: 2539.4" "Cancer enhanced" "Detected in all" "glioma: 528.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Rhabdoid: 118.1" "Breast - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026225 Approved "Secreted in other tissues" "No annotated function" NA NA 630000000 "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "CAB026225: " "unprognostic (1.02e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (1.19e-1)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (1.63e-3)" "unprognostic (1.73e-2)" "unprognostic (3.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-1)" "unprognostic (2.45e-3)" "unprognostic (1.76e-2)" "unprognostic (5.72e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (3.33e-4)" SPATA20 "FLJ21347, SSP411, Tisp78" ENSG00000006282 "Spermatogenesis associated 20" Q8TB22 17 50543058-50555852 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 114.3" "Group enriched" "Detected in all" 16 "Early spermatids: 449.2;Late spermatids: 1537.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA022023, HPA027144, HPA031442" Enhanced Approved Nucleoplasm "Secreted in male reproductive system" "Developmental protein" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" Nucleoplasm "HPA022023: AB_1857417, HPA027144: AB_1857418, HPA031442: AB_10610557" "unprognostic (9.27e-3)" "unprognostic (1.90e-1)" "unprognostic (9.60e-2)" "unprognostic (9.74e-3)" "unprognostic (2.63e-3)" "unprognostic (7.23e-2)" "unprognostic (1.56e-1)" "unprognostic (3.07e-1)" "unprognostic (7.09e-2)" "unprognostic (8.71e-2)" "unprognostic (6.12e-3)" "unprognostic (4.93e-2)" "unprognostic (6.74e-2)" "unprognostic (1.75e-1)" "unprognostic (2.29e-1)" "unprognostic (2.66e-1)" "prognostic favorable (9.69e-5)" SPATA6 "FLJ10007, SRF-1, SRF1" ENSG00000132122 "Spermatogenesis associated 6" Q9NWH7 1 48295373-48472208 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 48.6" "Cell type enriched" "Detected in many" 4 "Late spermatids: 4759.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.9" "Group enriched" "Detected in many" 4 "granulocytes: 3.6;monocytes: 5.9" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028234 Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 63: Late spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA028234: AB_2672532" "unprognostic (1.36e-2)" "unprognostic (2.96e-2)" "unprognostic (3.38e-2)" "unprognostic (2.87e-2)" "unprognostic (3.22e-1)" "unprognostic (1.68e-1)" "unprognostic (1.77e-2)" "unprognostic (4.69e-3)" "unprognostic (2.40e-2)" "unprognostic (2.61e-2)" "unprognostic (8.41e-2)" "unprognostic (6.50e-2)" "unprognostic (3.41e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-1)" "unprognostic (7.89e-2)" "unprognostic (5.71e-3)" SPESP1 SP-ESP ENSG00000258484 "Sperm equatorial segment protein 1" Q6UW49 15 68818221-68946811 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 70.8" "Group enriched" "Detected in many" 5 "Early spermatids: 552.9;Spermatocytes: 415.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 12.9;skin cancer: 11.0" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045936, HPA051040" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted in male reproductive system" "Developmental protein" NA NA 52000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 42: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "Nucleoplasm, Vesicles" Cytosol "HPA045936: AB_2679504, HPA051040: AB_2681322" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (9.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (1.06e-1)" "unprognostic (5.96e-2)" "unprognostic (2.79e-1)" "unprognostic (2.40e-1)" "unprognostic (8.99e-2)" "unprognostic (1.10e-2)" "unprognostic (1.16e-2)" "unprognostic (2.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (9.67e-2)" SPINK1 "PCTT, PSTI, Spink3, TATI" ENSG00000164266 "Serine peptidase inhibitor Kazal type 1" P00995 5 147824572-147831671 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "pancreas: 51319.3" "Cell type enriched" "Detected in many" 8 "Exocrine glandular cells: 37536.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 513.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 210.0;liver cancer: 259.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026366, HPA027498" Enhanced "Secreted to digestive system" "Enzyme inhibitor" NA NA 8000000 "Cluster 15: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "CAB026366: , HPA027498: AB_10603115" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (9.96e-3)" "unprognostic (3.55e-1)" "unprognostic (6.12e-3)" "unprognostic (1.79e-4)" "unprognostic (8.34e-3)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "unprognostic (1.88e-1)" "unprognostic (3.82e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.44e-7)" "unprognostic (7.98e-2)" "unprognostic (2.07e-1)" "prognostic favorable (2.15e-5)" SPINK13 "HESPINTOR, LiESP6, MGC149260, SPINK5L3" ENSG00000214510 "Serine peptidase inhibitor Kazal type 13" Q1W4C9 5 148268180-148286255 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "epididymis: 320.7" "Group enriched" "Detected in some" 23 "Basal prostatic cells: 90.8;Leydig cells: 39.8;Peritubular cells: 26.7" "Cancer enhanced" "Detected in some" "renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "cervical cancer: 97.7" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036456 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "Plasma membrane" Nucleoplasm "HPA036456: AB_10673496" "unprognostic (5.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.22e-1)" "unprognostic (1.41e-2)" "unprognostic (6.43e-3)" "unprognostic (1.25e-3)" "unprognostic (5.01e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (4.03e-10)" "unprognostic (4.31e-2)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (2.95e-2)" SPINK14 SPINK5L2 ENSG00000196800 "Serine peptidase inhibitor Kazal type 14 (putative)" Q6IE38 5 148168546-148175619 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" "Enzyme inhibitor" NA NA "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Hepatocytes - Metabolism" "unprognostic (4.98e-2)" "unprognostic (3.44e-1)" "unprognostic (1.94e-2)" "unprognostic (2.96e-2)" "unprognostic (5.69e-1)" "unprognostic (1.48e-3)" SPINK2 HUSI-II ENSG00000128040 "Serine peptidase inhibitor Kazal type 2" P20155 4 56809860-56821742 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "epididymis: 5123.9" "Group enriched" "Detected in many" 4 "Early spermatids: 1378.4;Late spermatids: 1361.0;Spermatocytes: 1693.1" "Group enriched" "Detected in some" 5 "lung cancer: 1.3;testis cancer: 4.6;thyroid cancer: 2.4" "Region enriched" "Detected in single" 5 "choroid plexus: 3.7" "Immune cell enriched" "Detected in many" 7 "NK-cell: 143.9" "Lineage enriched" "Detected in many" 7 "NK-cells: 143.9" "Group enriched" "Detected in some" 12 "Leukemia: 23.4;lymphoma: 17.3;Myeloma: 13.7" "Breast - Plasma cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB020824, HPA026813" Enhanced "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Spermatocytes - Spermatogenesis" 6 "CAB020824: , HPA026813: AB_1857446" "unprognostic (5.56e-3)" "unprognostic (3.60e-1)" "unprognostic (7.54e-2)" "unprognostic (2.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.60e-1)" "prognostic favorable (2.82e-4)" "unprognostic (9.83e-2)" "unprognostic (6.62e-2)" "unprognostic (9.40e-3)" "unprognostic (2.06e-1)" "unprognostic (2.49e-1)" "unprognostic (4.10e-3)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.87e-2)" SPINK4 "MGC133107, PEC-60" ENSG00000122711 "Serine peptidase inhibitor Kazal type 4" O60575 9 33218365-33248567 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 943.9" "Cell type enriched" "Detected in some" 24 "Intestinal goblet cells: 9780.8" "Group enriched" "Detected in many" 20 "colorectal cancer: 237.5;pancreatic cancer: 269.7;stomach cancer: 111.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "basophil: 1.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.8" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 146.3" "Colon - Colon enterocytes" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in some" HPA007286 Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Secreted to digestive system" "Enzyme inhibitor" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 45: Intestine - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Golgi apparatus, Vesicles" Nucleoplasm "HPA007286: AB_1080083" "unprognostic (3.49e-2)" "unprognostic (2.32e-1)" "prognostic favorable (8.85e-5)" "unprognostic (3.09e-4)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (9.66e-2)" "unprognostic (2.43e-1)" "unprognostic (1.24e-1)" "unprognostic (3.25e-1)" "unprognostic (2.42e-3)" SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 329.1;esophagus: 982.2;skin 1: 309.6;vagina: 565.0" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 10524.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 45.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 21.4" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" "Enzyme inhibitor" NA NA 43000000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" Vesicles "CAB015347: AB_2196138, HPA009067: AB_1080084, HPA011351: AB_1857447" "unprognostic (9.66e-3)" "unprognostic (1.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.42e-3)" "unprognostic (2.45e-2)" "unprognostic (6.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-3)" "unprognostic (4.56e-1)" "unprognostic (2.44e-1)" "unprognostic (7.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-2)" "unprognostic (2.59e-1)" SPINK6 "BUSI2, MGC21394, UNQ844" ENSG00000178172 "Serine peptidase inhibitor Kazal type 6" Q6UWN8 5 148202794-148215137 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.3;cervix: 5.5;salivary gland: 6.7;vagina: 9.8" "Group enriched" "Detected in some" 4 "Melanocytes: 6.9;Suprabasal keratinocytes: 12.9" "Group enriched" "Detected in many" 6 "cervical cancer: 21.4;head and neck cancer: 21.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 21 "cervical cancer: 1232.0" "Adipose visceral - Adipocytes (Visceral)" "Not detected" "Not detected" "Not detected" "Not detected" HPA011039 Uncertain "Secreted - unknown location" "Enzyme inhibitor" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA011039: AB_2668412" "unprognostic (2.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.65e-1)" "unprognostic (4.87e-2)" "prognostic favorable (7.16e-4)" "unprognostic (2.49e-2)" "unprognostic (4.04e-1)" "unprognostic (1.80e-2)" "unprognostic (2.09e-2)" "unprognostic (2.22e-2)" "unprognostic (1.29e-2)" "unprognostic (7.29e-2)" SPINK7 "ECG2, ECRG2" ENSG00000145879 "Serine peptidase inhibitor Kazal type 7" P58062 5 148312419-148315922 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 249.8;esophagus: 603.0;vagina: 595.4" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 259.8" "Group enriched" "Detected in many" 6 "cervical cancer: 4.5;head and neck cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 4.4;Esophageal cancer: 3.7;head and neck cancer: 10.1;lung cancer: 4.7" "Skin - Hair cortex cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036294 Enhanced "Secreted in other tissues" "Enzyme inhibitor" NA NA 230000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 59: Suprabasal keratinocytes - Cornification" 6 "HPA036294: AB_10671243" "unprognostic (2.82e-1)" "unprognostic (8.99e-3)" "unprognostic (8.52e-3)" "unprognostic (1.81e-1)" "unprognostic (1.12e-2)" "unprognostic (3.37e-2)" "unprognostic (9.10e-2)" "unprognostic (1.49e-1)" "unprognostic (6.86e-2)" "unprognostic (7.24e-2)" "unprognostic (4.22e-2)" SPINK8 ENSG00000229453 "Serine peptidase inhibitor Kazal type 8 (putative)" P0C7L1 3 48306842-48333661 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "bone marrow: 8.3;breast: 15.4;fallopian tube: 6.9;placenta: 5.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 18.0;Breast myoepithelial cells: 6.1;Excitatory neurons: 2.6;Melanocytes: 3.4" "Group enriched" "Detected in some" 10 "breast cancer: 8.6;glioma: 9.6;prostate cancer: 2.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 1.1;neutrophil: 1.8" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.8" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Region enriched" "Detected in many" 9 "hippocampal formation: 73.7" "Low region specificity" "Detected in all" HPA053151 Uncertain "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "HPA053151: AB_2682059" "prognostic unfavorable (8.47e-4)" "unprognostic (1.98e-1)" "unprognostic (1.75e-2)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.20e-1)" SPINK9 ENSG00000204909 "Serine peptidase inhibitor Kazal type 9" Q5DT21 5 148321203-148339852 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.4;lymphoid tissue: 2.7;retina: 2.1" "Cell type enriched" "Detected in some" 15 "Suprabasal keratinocytes: 18.2" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" HPA038288 Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" "Enzyme inhibitor" NA NA 24000 "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Nucleoplasm, Vesicles" "HPA038288: AB_10795400" "unprognostic (1.84e-1)" "unprognostic (4.87e-3)" "unprognostic (2.88e-1)" "unprognostic (9.02e-2)" "unprognostic (5.49e-3)" "unprognostic (3.04e-2)" "unprognostic (3.04e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (2.82e-2)" "unprognostic (1.91e-2)" "unprognostic (3.93e-1)" "unprognostic (2.01e-1)" "unprognostic (3.99e-2)" "unprognostic (1.90e-1)" SPINT1 "HAI, HAI-1, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 248.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1211.1;Ductal cells: 415.0;Proximal enterocytes: 467.2;Syncytiotrophoblasts: 1698.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" "Enzyme inhibitor" NA NA 7400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" SPINT3 HKIB9 ENSG00000101446 "Serine peptidase inhibitor, Kunitz type 3" P49223 20 45512461-45515622 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 4.7;seminal vesicle: 10.3" "Cell type enriched" "Detected in some" 5 "Basal prostatic cells: 17.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA026852 Enhanced "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 3: Basal prostatic cells - Lipid metabolism" "HPA026852: AB_2732434" SPINT4 "C20orf137, dJ601O1.1" ENSG00000149651 "Serine peptidase inhibitor, Kunitz type 4" Q6UDR6 20 45722347-45725830 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 257 "epididymis: 272.1" "Cell type enriched" "Detected in single" 12 "Rod photoreceptor cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046703 Enhanced "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 66: Photoreceptor cells - Visual perception" "HPA046703: AB_2732530" "unprognostic (3.61e-1)" SPOCK1 "SPOCK, testican-1, TIC1" ENSG00000152377 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1" Q08629 5 136975298-137598379 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 183.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 243.2;Inhibitory neurons: 335.0;Muller glia cells: 213.7;Oligodendrocyte precursor cells: 256.6;Oligodendrocytes: 849.8;Peritubular cells: 143.0" "Cancer enriched" "Detected in all" 7 "prostate cancer: 83.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 140.3;thyroid cancer: 129.8" "Kidney - Podocytes, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007450, HPA026770" Uncertain Approved Vesicles "Secreted to blood" "No annotated function" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 65: Cerebellum - Nervous system development" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" 2 Vesicles "HPA007450: AB_10603116, HPA026770: " "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.08e-4)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.72e-4)" "unprognostic (9.09e-3)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.77e-5)" "prognostic unfavorable (9.40e-4)" "unprognostic (1.26e-1)" "unprognostic (2.21e-1)" "unprognostic (1.90e-2)" SPOCK2 "KIAA0275, testican-2" ENSG00000107742 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2" Q92563 10 72059034-72089032 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 223.2;lymphoid tissue: 111.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 623.7;Bipolar cells: 105.1;Horizontal cells: 103.9;NK-cells: 129.9;Sertoli cells: 149.6;T-cells: 213.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 45.9;MAIT T-cell: 79.8;memory CD4 T-cell: 46.3;memory CD8 T-cell: 36.1;naive CD4 T-cell: 37.9;naive CD8 T-cell: 39.9;T-reg: 63.3" "Lineage enriched" "Detected in many" 8 "T-cells: 79.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 140.6;Uterine cancer: 69.7" "Colon - Colon enteroendocrine cells, Kidney - Podocytes, Liver - T-cells, Lung - Alveolar cells type 1, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044605 Enhanced "Secreted to blood" "No annotated function" NA NA 34000 "Cluster 11: T-cells - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "HPA044605: AB_10965991" "prognostic favorable (4.05e-4)" "unprognostic (3.11e-3)" "unprognostic (2.92e-2)" "unprognostic (2.29e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.95e-5)" "unprognostic (4.18e-2)" "unprognostic (9.04e-2)" "prognostic favorable (4.72e-4)" "prognostic unfavorable (7.19e-4)" "unprognostic (4.53e-3)" "unprognostic (2.29e-1)" "unprognostic (1.46e-3)" "unprognostic (5.59e-2)" "unprognostic (5.49e-2)" "unprognostic (3.19e-3)" "unprognostic (2.24e-2)" SPOCK3 testican-3 ENSG00000196104 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3" Q9BQ16 4 166733384-167234796 "Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 132.3;parathyroid gland: 169.6;prostate: 71.4" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 968.4;Oligodendrocyte precursor cells: 374.5;Oligodendrocytes: 1723.2" "Cancer enhanced" "Detected in many" "prostate cancer: 7.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.2;myeloid DC: 1.8" "Group enriched" "Detected in many" 12 "dendritic cells: 1.8;monocytes: 1.2" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 17.9;Rhabdoid: 26.3" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "unprognostic (3.54e-2)" "unprognostic (8.69e-2)" "unprognostic (2.90e-3)" "unprognostic (1.20e-1)" "unprognostic (4.09e-4)" "unprognostic (3.75e-1)" "unprognostic (1.97e-2)" "unprognostic (1.44e-1)" "unprognostic (1.88e-1)" "unprognostic (3.94e-4)" "unprognostic (8.92e-2)" "unprognostic (4.18e-3)" "unprognostic (2.62e-2)" "unprognostic (2.48e-1)" "unprognostic (3.60e-3)" "unprognostic (1.64e-1)" SPON1 "f-spondin, KIAA0762" ENSG00000262655 "Spondin 1" Q9HCB6 11 13962723-14268133 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 379.3;Endometrial stromal cells: 80.3;Muller glia cells: 146.2" "Cancer enriched" "Detected in all" 5 "ovarian cancer: 199.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 3.3" "Lineage enriched" "Detected in single" 33 "T-cells: 3.3" "Group enriched" "Detected in many" 8 "ovarian cancer: 127.8;Uterine cancer: 91.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077546 Uncertain "Secreted to blood" "Cell adhesion" NA No 11500000 28000000 "Cluster 1: T-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Astrocytes - Unknown function" 2 "HPA077546: AB_2732351" "unprognostic (1.66e-1)" "unprognostic (1.03e-2)" "unprognostic (8.36e-2)" "unprognostic (8.72e-2)" "unprognostic (1.52e-1)" "unprognostic (3.76e-2)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (1.05e-1)" "unprognostic (5.93e-2)" "unprognostic (6.45e-2)" "unprognostic (1.07e-1)" "prognostic favorable (3.12e-4)" "unprognostic (7.22e-3)" "unprognostic (7.89e-2)" "unprognostic (4.65e-2)" "prognostic unfavorable (1.88e-4)" SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 180.9" "Cell type enhanced" "Detected in many" "dendritic cells: 166.7;Endometrial stromal cells: 253.2;Extravillous trophoblasts: 425.1;Fibroblasts: 193.0;NK-cells: 910.5" "Cancer enriched" "Detected in all" 7 "prostate cancer: 243.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 256.9" "Lineage enriched" "Detected in all" 5 "T-cells: 256.9" "Cancer enriched" "Detected in many" 9 "prostate cancer: 639.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" Immunity NA NA 2600000 "Cluster 1: T-cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" 3 Vesicles "HPA040170: AB_2676868, HPA066095: AB_2685615" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (3.07e-2)" "prognostic favorable (2.03e-4)" "unprognostic (7.64e-2)" "unprognostic (6.28e-2)" "unprognostic (2.70e-3)" "unprognostic (2.28e-3)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-3)" "unprognostic (1.22e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (9.22e-4)" SPP1 "BNSP, BSPI, ETA-1, OPN" ENSG00000118785 "Secreted phosphoprotein 1" P10451 4 87975667-87983532 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Biomineralization, Cell adhesion" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 1980.6;gallbladder: 2349.6;kidney: 3486.9;placenta: 2701.1" "Cell type enriched" "Detected in many" 6 "Hofbauer cells: 52047.2" "Group enriched" "Detected in all" 4 "glioma: 1690.9;renal cancer: 1385.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "neutrophil: 26.6" "Lineage enriched" "Detected in single" 266 "granulocytes: 26.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 4186.2;Kidney cancer: 2365.8" "Adipose subcutaneous - Macrophages" "Region enhanced" "Detected in all" "pons and medulla: 317.0" "Low region specificity" "Detected in all" "HPA027540, HPA027541" Enhanced Enhanced "Golgi apparatus" "Secreted to blood" Cytokine NA NA 114000000 73000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" 7 "Golgi apparatus" "HPA027540: AB_10600222, HPA027541: AB_10601446" "unprognostic (4.74e-2)" "prognostic unfavorable (9.52e-4)" "unprognostic (1.13e-3)" "unprognostic (2.04e-1)" "unprognostic (2.31e-2)" "unprognostic (6.96e-3)" "prognostic unfavorable (2.84e-6)" "unprognostic (2.46e-3)" "unprognostic (7.86e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (5.89e-4)" "unprognostic (4.31e-2)" "unprognostic (2.55e-1)" "unprognostic (7.19e-2)" "unprognostic (1.57e-1)" "unprognostic (3.48e-1)" "unprognostic (2.63e-2)" SPP2 SPP24 ENSG00000072080 "Secreted phosphoprotein 2" Q13103 2 234050679-234077134 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4403 "liver: 502.9" "Cell type enriched" "Detected in some" 28 "Hepatocytes: 246.6" "Cancer enriched" "Detected in some" 112 "liver cancer: 65.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" "No annotated function" NA NA 480000000 "Cluster 31: Liver - Plasma proteins" "Cluster 5: Rhabdoid - Unknown function" "Cluster 43: Hepatocytes - Metabolism" "prognostic favorable (2.33e-6)" "unprognostic (7.02e-3)" "unprognostic (9.62e-3)" SPRING1 "C12orf49, FLJ21415, LUR1, POST1, SPRING" ENSG00000111412 "SREBF pathway regulator in golgi 1" Q9H741 12 116710171-116738070 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 36.3" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 154.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026905 Uncertain "Intracellular and membrane" "No annotated function" NA NA 330000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 72: Alveolar cells - Lung function" 3 "HPA026905: AB_10603446" "unprognostic (2.74e-3)" "unprognostic (1.41e-1)" "unprognostic (3.66e-2)" "unprognostic (9.19e-2)" "unprognostic (1.30e-1)" "unprognostic (5.76e-2)" "prognostic unfavorable (8.44e-4)" "unprognostic (2.56e-1)" "unprognostic (4.78e-2)" "unprognostic (2.62e-2)" "unprognostic (3.72e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.91e-11)" "unprognostic (3.28e-2)" "unprognostic (2.25e-1)" "unprognostic (8.46e-2)" "unprognostic (1.73e-1)" SPRN "bA108K14.1, FLJ41197, Shadoo" ENSG00000203772 "Shadow of prion protein" Q5BIV9 10 133420666-133424625 "Predicted intracellular proteins, Transporters" Prion "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.1;liver: 17.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.3;Hepatocytes: 17.1;Horizontal cells: 7.6;Inhibitory neurons: 4.9;Kupffer cells: 27.3;Oligodendrocyte precursor cells: 4.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Other NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 62: Hepatocytes - Metabolism" "unprognostic (2.66e-1)" "unprognostic (1.64e-3)" "unprognostic (3.38e-3)" "unprognostic (1.95e-1)" "unprognostic (1.35e-1)" "unprognostic (3.31e-2)" "unprognostic (1.07e-1)" "unprognostic (3.90e-3)" "unprognostic (1.68e-1)" "unprognostic (2.07e-1)" "prognostic favorable (1.54e-6)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.76e-2)" "unprognostic (1.13e-1)" "unprognostic (7.17e-2)" "prognostic favorable (1.58e-7)" SPRR2A ENSG00000241794 "Small proline rich protein 2A" P35326 1 153056120-153057512 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 5114.8" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 2296.6;Serous glandular cells: 1801.8;Suprabasal keratinocytes: 3409.5" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 743.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 43.1" "Secreted to digestive system" Defense NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 2 "unprognostic (3.15e-1)" "unprognostic (2.48e-1)" "unprognostic (3.11e-3)" "unprognostic (1.64e-2)" "unprognostic (6.80e-3)" "unprognostic (3.51e-1)" "unprognostic (3.36e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.37e-5)" SPTY2D1OS "Kastor, Polluks, SPTY2D1-AS1" ENSG00000247595 "SPTY2D1 opposite strand" A0A0U1RRN3 11 18588781-18610255 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in many" 34 "testis: 473.9" "Cell type enriched" "Detected in many" 5 "Late spermatids: 10457.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Intracellular and membrane" "No annotated function" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 63: Late spermatids - Spermatogenesis" "unprognostic (1.07e-1)" "unprognostic (1.24e-1)" "unprognostic (8.60e-3)" "unprognostic (5.14e-2)" "unprognostic (6.61e-2)" "unprognostic (9.32e-2)" "unprognostic (4.44e-7)" "unprognostic (1.75e-1)" "unprognostic (1.39e-2)" "unprognostic (7.83e-2)" "unprognostic (5.36e-2)" "unprognostic (6.50e-3)" "unprognostic (5.41e-4)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.91e-1)" "unprognostic (1.48e-2)" SPX "C12orf39, MGC10946, NPQ, spexin" ENSG00000134548 "Spexin hormone" Q9BT56 12 21526296-21541249 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adipose tissue: 107.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 56.0;Collecting duct cells: 27.2;Distal tubular cells: 83.0;Proximal tubular cells: 237.4" "Cancer enriched" "Detected in many" 5 "renal cancer: 13.5" "Region enhanced" "Detected in all" "pons: 42.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 13.1;testis cancer: 13.4" "Breast - Adipocytes (Breast), Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skin - Adipocytes (Skin), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebral cortex: 22.1;hippocampal formation: 22.7;olfactory bulb: 10.3;pons: 10.7" "Secreted to blood" Hormone NA NA 2650000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "unprognostic (2.78e-2)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (1.81e-2)" "unprognostic (2.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (5.89e-2)" "unprognostic (1.21e-2)" "unprognostic (1.95e-1)" "prognostic favorable (1.31e-6)" "unprognostic (2.37e-3)" "unprognostic (9.78e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" SRGN "PPG, PRG, PRG1" ENSG00000122862 Serglycin P10124 10 69088103-69104805 "Plasma proteins, Predicted secreted proteins" "Apoptosis, Biomineralization" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "bone marrow: 7997.0" "Cell type enhanced" "Detected in many" "dendritic cells: 2676.1;granulocytes: 5607.3;Hofbauer cells: 2504.6;Langerhans cells: 8237.9;Macrophages: 3447.1;monocytes: 10974.4;NK-cells: 3726.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 5737.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 5737.5" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 1066.9;Leukemia: 1148.5" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000759 Enhanced Supported "Golgi apparatus" "Secreted to blood" Other NA NA 100000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 8 "Golgi apparatus" "HPA000759: AB_1079675" "unprognostic (3.61e-2)" "unprognostic (1.62e-2)" "unprognostic (2.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.37e-1)" "unprognostic (4.50e-2)" "unprognostic (1.30e-1)" "unprognostic (1.70e-2)" "unprognostic (1.63e-1)" "unprognostic (8.22e-2)" "unprognostic (5.80e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (1.65e-1)" "unprognostic (2.32e-2)" "unprognostic (4.07e-2)" "unprognostic (4.08e-2)" SRL SAR ENSG00000185739 Sarcalumenin Q86TD4 16 4189374-4242080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 40 "heart muscle: 271.0;skeletal muscle: 492.3;tongue: 367.5" "Group enriched" "Detected in some" 12 "Cardiomyocytes: 230.6;Skeletal myocytes: 64.4" "Group enriched" "Detected in some" 5 "head and neck cancer: 1.5;thyroid cancer: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "lung cancer: 1.4;lymphoma: 3.6;Sarcoma: 2.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 7.0" "HPA041535, HPA045520" Enhanced "Intracellular and membrane" "No annotated function" NA NA 230000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA041535: AB_2677538, HPA045520: AB_2679358" "unprognostic (1.24e-2)" "unprognostic (1.36e-2)" "unprognostic (1.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.21e-1)" "unprognostic (8.11e-2)" "unprognostic (2.04e-7)" "unprognostic (1.41e-1)" "unprognostic (8.28e-2)" "unprognostic (7.40e-4)" "unprognostic (4.91e-2)" "unprognostic (8.70e-2)" "unprognostic (7.78e-4)" "unprognostic (3.33e-2)" "unprognostic (2.15e-1)" "unprognostic (1.51e-3)" "unprognostic (1.68e-4)" SRPX "ETX1, SRPX1" ENSG00000101955 "Sushi repeat containing protein X-linked" P78539 X 38149336-38220924 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 208.3" "Cell type enhanced" "Detected in many" "Endothelial cells: 67.2;Fibroblasts: 249.2;Leydig cells: 104.3;Melanocytes: 75.6;Peritubular cells: 98.4;Smooth muscle cells: 100.0" "Group enriched" "Detected in all" 5 "glioma: 64.2;melanoma: 70.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 49 "plasmacytoid DC: 7.8" "Lineage enriched" "Detected in single" 49 "dendritic cells: 7.8" "Cancer enhanced" "Detected in many" "skin cancer: 188.4" "Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "spinal cord: 17.6" "Secreted - unknown location" "Cell adhesion" NA NA 140000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "unprognostic (2.35e-1)" "unprognostic (1.09e-3)" "unprognostic (1.08e-3)" "prognostic unfavorable (1.18e-4)" "unprognostic (6.48e-2)" "unprognostic (3.83e-3)" "unprognostic (3.50e-2)" "unprognostic (2.31e-1)" "unprognostic (4.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (7.80e-13)" "unprognostic (6.94e-3)" "unprognostic (3.90e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.36e-4)" SRPX2 SRPUL ENSG00000102359 "Sushi repeat containing protein X-linked 2" O60687 X 100644195-100675788 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.8" "Cell type enhanced" "Detected in many" "Adipocytes: 17.9;Club cells: 24.8;Fibroblasts: 49.8;Leydig cells: 26.3;Microglial cells: 35.8;Ovarian stromal cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Endothelial cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "midbrain: 1.0;spinal cord: 3.4" HPA038786 Approved "Secreted to blood" "Cell adhesion" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA038786: AB_10672724" "unprognostic (4.10e-2)" "unprognostic (4.55e-2)" "unprognostic (2.08e-1)" "unprognostic (3.72e-2)" "unprognostic (1.96e-1)" "unprognostic (4.21e-3)" "unprognostic (3.59e-3)" "unprognostic (5.41e-2)" "unprognostic (3.22e-2)" "unprognostic (1.26e-1)" "unprognostic (2.86e-2)" "unprognostic (2.29e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.84e-3)" "unprognostic (1.69e-1)" "unprognostic (8.67e-2)" "unprognostic (3.85e-1)" SSC4D "S4D-SRCRB, SRCRB-S4D, SRCRB4D" ENSG00000146700 "Scavenger receptor cysteine rich family member with 4 domains" Q8WTU2 7 76389334-76409697 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.6;parathyroid gland: 6.8;pituitary gland: 2.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 11.7;Granulosa cells: 3.8;Spermatogonia: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA062611 Uncertain "Secreted - unknown location" "No annotated function" NA NA 980000 "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Muller glia cells - Visual perception" "HPA062611: AB_2684807" "unprognostic (3.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (2.83e-6)" "prognostic unfavorable (7.08e-4)" "unprognostic (3.52e-2)" "unprognostic (3.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.49e-2)" "unprognostic (8.49e-3)" "unprognostic (3.18e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (4.71e-4)" "unprognostic (2.59e-1)" "unprognostic (3.90e-1)" "unprognostic (2.56e-2)" "unprognostic (1.73e-2)" SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 38.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 18.5;Fibroblasts: 28.1;Leydig cells: 18.2;Peritubular cells: 15.1;Schwann cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 13.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Receptor Yes NA 88000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 15 "Nucleoplasm, Cytosol" "HPA042008: AB_10804124, HPA053316: " "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.28e-2)" "unprognostic (4.55e-2)" "unprognostic (6.65e-2)" "unprognostic (3.68e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.34e-3)" "unprognostic (1.40e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (4.26e-8)" "unprognostic (7.73e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-2)" "unprognostic (2.21e-3)" SST "SMST, SST1" ENSG00000157005 Somatostatin P61278 3 187668912-187670394 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 593.7;intestine: 375.1;pancreas: 465.7;stomach 1: 406.4" "Cell type enriched" "Detected in some" 33 "Enteroendocrine cells: 4713.7" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 1039.3" "Region enhanced" "Detected in all" "hypothalamus: 999.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Neuroblastoma: 145.1;thyroid cancer: 489.5" "Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Inner root sheath cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000075, HPA019472, CAB034105" Enhanced Supported "Secreted to blood" Hormone NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 "CAB000075: AB_2688022, CAB034105: AB_2271061, HPA019472: AB_1857360" "unprognostic (2.44e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.12e-3)" "unprognostic (1.54e-2)" "unprognostic (4.69e-1)" "unprognostic (3.31e-2)" "unprognostic (8.16e-3)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (8.47e-2)" "unprognostic (4.19e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" ST3GAL1 "SIAT4A, SIATFL, ST3GalA.1, ST3O" ENSG00000008513 "ST3 beta-galactoside alpha-2,3-sialyltransferase 1" Q11201 8 133454848-133571940 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 138.0;monocytes: 152.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040466 Approved "Intracellular and membrane" Enzyme NA NA 860000 "Cluster 22: Eosinophils - Transcription" "Cluster 35: Non-specific - Mitochondria" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA040466: AB_10805712" "unprognostic (1.36e-2)" "unprognostic (1.11e-2)" "unprognostic (6.66e-2)" "unprognostic (1.83e-3)" "unprognostic (5.53e-3)" "unprognostic (4.43e-2)" "unprognostic (4.79e-2)" "unprognostic (2.66e-1)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (3.55e-3)" "unprognostic (1.10e-1)" "unprognostic (1.83e-3)" "unprognostic (1.67e-2)" "unprognostic (3.29e-2)" "unprognostic (8.64e-3)" "unprognostic (2.95e-2)" ST3GAL2 "SIAT4B, ST3GalA.2, ST3GALII" ENSG00000157350 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" Q16842 16 70375977-70439237 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 82.4;Langerhans cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017270 Approved Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 28: Dendritic cells - Antigen presentation" Vesicles "HPA017270: AB_1857523" "unprognostic (2.76e-2)" "unprognostic (6.33e-2)" "unprognostic (3.41e-1)" "unprognostic (1.35e-1)" "unprognostic (4.99e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.14e-2)" "unprognostic (2.21e-1)" "unprognostic (1.91e-2)" "prognostic favorable (2.33e-4)" "unprognostic (9.54e-2)" "prognostic unfavorable (3.34e-6)" "unprognostic (7.42e-2)" "unprognostic (8.83e-3)" "unprognostic (4.64e-2)" "unprognostic (5.20e-2)" ST3GAL3 "MRT12, SIAT6" ENSG00000126091 "ST3 beta-galactoside alpha-2,3-sialyltransferase 3" Q11203 1 43705824-43931165 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.9;tongue: 79.6" "Cell type enhanced" "Detected in many" "Astrocytes: 56.7;Excitatory neurons: 91.3;Inhibitory neurons: 115.2;Microglial cells: 54.6;Oligodendrocyte precursor cells: 62.7;Oligodendrocytes: 61.6;Rod photoreceptor cells: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051102 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 8: Neurons - Neuronal signaling" 1 "HPA051102: AB_2681344" "unprognostic (8.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-2)" "unprognostic (5.18e-2)" "unprognostic (1.22e-1)" "unprognostic (3.20e-1)" "unprognostic (9.72e-2)" "unprognostic (7.01e-2)" "unprognostic (4.39e-2)" "unprognostic (2.33e-2)" "unprognostic (1.38e-3)" "unprognostic (7.00e-2)" "unprognostic (3.68e-3)" "unprognostic (1.67e-2)" "unprognostic (1.30e-1)" "unprognostic (4.35e-1)" "unprognostic (6.60e-2)" ST3GAL4 "CGS23, FLJ11867, NANTA3, SAT3, SIAT4, SIAT4C, STZ" ENSG00000110080 "ST3 beta-galactoside alpha-2,3-sialyltransferase 4" Q11206 11 126355640-126440344 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Syncytiotrophoblasts: 1032.1" "Cancer enhanced" "Detected in all" "melanoma: 57.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 112.4;neutrophil: 72.1;plasmacytoid DC: 93.9" "Group enriched" "Detected in many" 12 "dendritic cells: 93.9;granulocytes: 112.4" "Cancer enriched" "Detected in all" 4 "skin cancer: 242.2" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049827 Approved "Intracellular and membrane" Enzyme NA NA 15000 "Cluster 41: Basophils - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA049827: AB_2680900" "unprognostic (8.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.92e-2)" "unprognostic (6.93e-2)" "unprognostic (8.33e-2)" "unprognostic (3.80e-2)" "unprognostic (2.71e-3)" "unprognostic (1.90e-3)" "unprognostic (2.62e-1)" "unprognostic (1.80e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (3.16e-3)" "unprognostic (2.79e-2)" "unprognostic (1.28e-1)" "unprognostic (8.36e-3)" "unprognostic (8.78e-3)" ST6GAL1 "CDw75, SIAT1" ENSG00000073849 "ST6 beta-galactoside alpha-2,6-sialyltransferase 1" P15907 3 186930325-187078553 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 480.8;lymphoid tissue: 143.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 510.2;Kupffer cells: 166.2;Microglial cells: 575.3;Plasma cells: 160.3" "Cancer enhanced" "Detected in all" "liver cancer: 70.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 138.9;Myeloma: 151.6" "Liver - Hepatocytes, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015018, CAB016122" Supported "Secreted to blood" Enzyme NA NA 15000000 3300000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 83: Liver - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 62: Hepatocytes - Metabolism" "CAB015018: AB_629203, CAB016122: AB_627178" "unprognostic (5.85e-3)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (2.64e-1)" "unprognostic (2.44e-2)" "unprognostic (1.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (3.99e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" "unprognostic (7.30e-3)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-2)" ST6GALNAC2 "SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM" ENSG00000070731 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 2" Q9UJ37 17 76565377-76586956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 127.0" "Group enriched" "Detected in some" 5 "Basal squamous epithelial cells: 26.6;Late spermatids: 12.8;Schwann cells: 11.4;Squamous epithelial cells: 17.2" "Cancer enhanced" "Detected in all" "melanoma: 22.0" "Region enriched" "Detected in many" 5 "choroid plexus: 69.7" "Immune cell enriched" "Detected in some" 9 "neutrophil: 47.2" "Lineage enriched" "Detected in many" 16 "granulocytes: 47.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 30.5;skin cancer: 29.4" "Breast - Breast myoepithelial cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" "unprognostic (8.93e-3)" "unprognostic (5.86e-3)" "unprognostic (1.67e-2)" "unprognostic (5.18e-3)" "unprognostic (3.37e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.95e-1)" "unprognostic (5.37e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.57e-1)" "unprognostic (5.17e-3)" "unprognostic (3.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" ST6GALNAC5 "MGC3184, SIAT7E, ST6GalNAcV" ENSG00000117069 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5" Q9BVH7 1 76867480-77067546 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.4" "Group enriched" "Detected in some" 12 "Excitatory neurons: 465.6;Inhibitory neurons: 400.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.1;Neuroblastoma: 3.0" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 68.3" "HPA065593, HPA070354" Uncertain Approved Vesicles "Intracellular and membrane" Enzyme NA Yes 180000 "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 8: Neurons - Neuronal signaling" Vesicles "HPA065593: AB_2685515, HPA070354: AB_2686260" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (1.72e-1)" "unprognostic (1.49e-2)" "unprognostic (2.82e-2)" "unprognostic (2.04e-2)" "unprognostic (4.67e-2)" "unprognostic (2.72e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.10e-2)" "unprognostic (5.90e-3)" "unprognostic (9.66e-2)" "unprognostic (6.88e-2)" "unprognostic (1.69e-2)" ST6GALNAC6 "SIAT7F, ST6GALNACVI" ENSG00000160408 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6" Q969X2 9 127885321-127905408 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 12.4;Excitatory neurons: 11.1;Inhibitory neurons: 10.2;NK-cells: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "NK-cells: 23.7;T-cells: 25.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018890, HPA072757" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 1: T-cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 49: Non-specific - Transcription" 2 Cytosol "HPA018890: AB_1857531, HPA072757: " "unprognostic (2.27e-1)" "unprognostic (5.23e-2)" "unprognostic (2.81e-1)" "unprognostic (4.54e-2)" "unprognostic (1.81e-2)" "unprognostic (5.71e-2)" "unprognostic (1.36e-1)" "unprognostic (4.84e-2)" "unprognostic (6.05e-2)" "unprognostic (1.40e-3)" "unprognostic (3.24e-3)" "unprognostic (3.31e-2)" "unprognostic (3.29e-1)" "unprognostic (1.10e-2)" "unprognostic (9.85e-2)" "unprognostic (3.46e-2)" "unprognostic (2.67e-2)" ST8SIA2 "HsT19690, SIAT8B, ST8SIA-II, STX" ENSG00000140557 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2" Q92186 15 92393881-92468728 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 3.7;lymphoid tissue: 1.7" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 2.6;Cardiomyocytes: 3.5;Horizontal cells: 1.9;Inhibitory neurons: 3.3;Muller glia cells: 1.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 18.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Myeloma: 7.8;Neuroblastoma: 18.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA054518, HPA057819" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 10: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA054518: AB_2682514, HPA057819: " "unprognostic (4.70e-2)" "unprognostic (2.48e-2)" "unprognostic (1.26e-1)" "unprognostic (9.32e-3)" "unprognostic (1.03e-1)" "unprognostic (2.87e-2)" "unprognostic (2.32e-1)" "unprognostic (1.28e-5)" "unprognostic (3.91e-2)" "unprognostic (5.39e-3)" "unprognostic (1.59e-2)" "unprognostic (4.44e-3)" "unprognostic (4.78e-2)" "unprognostic (2.29e-1)" "unprognostic (3.16e-1)" "unprognostic (3.00e-1)" ST8SIA4 "PST, PST1, SIAT8D" ENSG00000113532 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4" Q92187 5 100806933-100903282 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.6" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 70.5;Kupffer cells: 75.0;Langerhans cells: 176.6;Microglial cells: 96.6;monocytes: 96.0;Schwann cells: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 91.9" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 10.5;lymphoma: 14.1;Myeloma: 17.3" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036437, HPA051126, HPA053995" Approved Supported "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 980000 "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" "Golgi apparatus" "HPA036437: , HPA051126: AB_2681352, HPA053995: AB_2682336" "unprognostic (2.25e-1)" "unprognostic (2.04e-2)" "unprognostic (1.04e-1)" "unprognostic (1.98e-2)" "unprognostic (1.14e-1)" "unprognostic (6.45e-3)" "unprognostic (1.91e-1)" "unprognostic (5.46e-2)" "unprognostic (2.87e-1)" "unprognostic (1.49e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.80e-7)" "unprognostic (6.07e-2)" "unprognostic (4.38e-2)" "unprognostic (1.30e-1)" "unprognostic (1.23e-2)" ST8SIA6 SIAT8F ENSG00000148488 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6" P61647 10 17315421-17454595 "Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.0;epididymis: 4.5;lung: 5.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 24.5;Erythroid cells: 37.0;granulocytes: 48.8;Microglial cells: 131.5" "Cancer enhanced" "Detected in some" "breast cancer: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "breast cancer: 1.9;Leukemia: 7.1;Rhabdoid: 2.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Breast glandular cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011635, HPA072708" Uncertain Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Endoplasmic reticulum" "HPA011635: AB_2194921, HPA072708: " "unprognostic (4.86e-3)" "unprognostic (7.01e-2)" "unprognostic (5.85e-3)" "unprognostic (2.21e-2)" "unprognostic (3.43e-2)" "unprognostic (2.21e-2)" "unprognostic (1.11e-2)" "unprognostic (6.81e-2)" "unprognostic (2.32e-1)" "unprognostic (3.23e-2)" "unprognostic (7.53e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (3.26e-4)" "unprognostic (2.43e-1)" "unprognostic (2.22e-1)" "unprognostic (1.07e-3)" STARD7 GTT1 ENSG00000084090 "StAR related lipid transfer domain containing 7" Q9NQZ5 2 96184859-96208827 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 217.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033965, HPA064958, HPA064978" Supported Approved Mitochondria "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 55: Non-specific - Transcription" 1 Mitochondria "CAB033965: AB_2302780, HPA064958: AB_2685391, HPA064978: AB_2685397" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.56e-5)" "prognostic favorable (3.89e-6)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (2.72e-3)" "unprognostic (2.38e-1)" "unprognostic (2.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.38e-6)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (2.64e-2)" "unprognostic (2.42e-2)" STATH STR ENSG00000126549 Statherin P02808 4 69995966-70002570 "Plasma proteins, Predicted secreted proteins, Transporters" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 925 "salivary gland: 8851.0" "Cell type enriched" "Detected in some" 40 "Serous glandular cells: 164994.2" "Group enriched" "Detected in some" 14 "head and neck cancer: 3.5;lung cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Sarcoma: 2.3" HPA044569 Enhanced "Secreted to digestive system" Other NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 75: Serous glandular cells - Salivary secretion" 21 "HPA044569: AB_10966146" "unprognostic (2.00e-2)" STC1 STC ENSG00000159167 "Stanniocalcin 1" P52823 8 23841929-23854806 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 163.8;Collecting duct cells: 72.0;Endothelial cells: 178.9;Glandular and luminal cells: 302.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB018625, HPA023918" Approved "Secreted in other tissues" Hormone NA NA 240000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" "CAB018625: AB_2197536, HPA023918: AB_1857566" "unprognostic (1.18e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (3.58e-2)" "unprognostic (2.13e-1)" "prognostic unfavorable (6.44e-5)" "prognostic unfavorable (6.32e-4)" "unprognostic (2.84e-2)" "prognostic unfavorable (1.53e-4)" "unprognostic (4.82e-2)" "unprognostic (1.44e-2)" "unprognostic (7.61e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.23e-6)" "prognostic unfavorable (5.55e-4)" "unprognostic (2.79e-1)" "unprognostic (1.19e-3)" "unprognostic (8.95e-3)" STC2 STC-2 ENSG00000113739 "Stanniocalcin 2" O76061 5 173314723-173328447 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "breast: 139.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 236.3;Breast myoepithelial cells: 119.4;Cytotrophoblasts: 38.6;Extravillous trophoblasts: 63.4;Pancreatic endocrine cells: 52.6" "Cancer enriched" "Detected in all" 6 "breast cancer: 91.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Macrophages" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA045372 Approved Approved "Endoplasmic reticulum" "Secreted in other tissues" Hormone NA NA 19000000 "Cluster 73: Breast - Lactation" "Cluster 27: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 17: Breast glandular cells - Lactation" "Endoplasmic reticulum" "HPA045372: AB_10961040" "prognostic favorable (7.40e-5)" "unprognostic (2.40e-2)" "unprognostic (9.03e-3)" "unprognostic (1.21e-1)" "unprognostic (1.89e-3)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (3.07e-5)" "unprognostic (5.28e-3)" "unprognostic (6.12e-3)" "unprognostic (1.53e-1)" "unprognostic (2.13e-1)" "unprognostic (3.19e-1)" "prognostic unfavorable (4.17e-8)" "prognostic unfavorable (7.57e-4)" "unprognostic (8.56e-2)" "unprognostic (5.06e-2)" "unprognostic (7.93e-3)" STMP1 "C7orf73, Mm47, PL-5283" ENSG00000243317 "Short transmembrane mitochondrial protein 1" E0CX11 7 135662496-135693418 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 433.1;eosinophil: 127.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 433.1" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065565 Approved Mitochondria "Intracellular and membrane" Immunity NA NA "Cluster 41: Basophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" 1 Mitochondria "HPA065565: AB_2685512" "unprognostic (3.94e-2)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (3.11e-2)" "unprognostic (3.64e-2)" "unprognostic (1.81e-1)" "unprognostic (2.99e-3)" "unprognostic (1.12e-1)" "unprognostic (4.43e-3)" "prognostic favorable (2.95e-4)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (7.21e-3)" "unprognostic (4.90e-2)" "unprognostic (9.99e-2)" "unprognostic (9.62e-3)" "unprognostic (6.81e-2)" STOML2 "HSPC108, SLP-2" ENSG00000165283 "Stomatin like 2" Q9UJZ1 9 35099776-35103195 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015944, HPA062016" Supported Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 44000 "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 3 "Plasma membrane, Cytosol" "CAB015944: , HPA062016: AB_2684659" "unprognostic (2.49e-1)" "unprognostic (2.69e-1)" "unprognostic (1.20e-2)" "unprognostic (9.43e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (5.14e-2)" "unprognostic (4.25e-2)" "unprognostic (1.04e-2)" "unprognostic (9.06e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.00e-5)" "unprognostic (2.74e-2)" "unprognostic (5.26e-1)" "unprognostic (2.67e-1)" "unprognostic (5.47e-2)" STOX1 "C10orf24, FLJ25162" ENSG00000165730 "Storkhead box 1" Q6ZVD7 10 68827531-68895432 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0;choroid plexus: 26.9" "Group enriched" "Detected in many" 5 "Astrocytes: 80.8;Ciliated cells: 59.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA037844, HPA037845" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" "Intracellular and membrane" Transcription No NA "Cluster 24: Non-specific - Transcription" "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 52: Non-specific - Mitochondria" "Cluster 42: Ciliated cells - Cilium assembly" 2 Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA037844: AB_2675700, HPA037845: AB_10671369" "prognostic favorable (3.37e-5)" "unprognostic (5.53e-3)" "unprognostic (6.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.63e-3)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "prognostic favorable (2.08e-4)" "unprognostic (1.52e-1)" "unprognostic (2.45e-3)" "unprognostic (5.33e-3)" "unprognostic (5.29e-2)" "unprognostic (3.87e-2)" "unprognostic (8.77e-2)" "unprognostic (3.06e-2)" "unprognostic (2.33e-1)" "unprognostic (3.46e-2)" STX1A "HPC-1, p35-1, STX1" ENSG00000106089 "Syntaxin 1A" Q16623 7 73699206-73719672 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Exocytosis, Neurotransmitter transport, Transport" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 174.8;pituitary gland: 95.9" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 29.5;Excitatory neurons: 58.6;Pancreatic endocrine cells: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pancreas - Alpha cells, Pancreas - Beta cells" "Group enriched" "Detected in all" 5 "amygdala: 246.4;basal ganglia: 93.9;cerebral cortex: 354.5;hippocampal formation: 229.2;white matter: 116.1" "Group enriched" "Detected in all" 8 "amygdala: 48.7;cerebral cortex: 134.1;hippocampal formation: 113.2" "CAB008372, HPA069176" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" Transport NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 96 Vesicles "Nuclear membrane" "CAB008372: AB_592786, HPA069176: AB_2686098" "unprognostic (5.12e-3)" "prognostic unfavorable (3.63e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (1.94e-5)" "unprognostic (3.12e-3)" "unprognostic (1.88e-1)" "unprognostic (3.02e-8)" "unprognostic (1.11e-2)" "unprognostic (6.97e-2)" "unprognostic (3.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.70e-3)" "unprognostic (4.18e-6)" "unprognostic (2.65e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-3)" "unprognostic (6.20e-2)" SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 533.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 771.4;Proximal enterocytes: 644.2;Proximal tubular cells: 3002.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" Enzyme NA NA 350000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" SUDS3 "FLJ00052, SAP45, SDS3" ENSG00000111707 "SDS3 homolog, SIN3A corepressor complex component" Q9H7L9 12 118376555-118418033 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 289.1;Oocytes: 227.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040402, HPA041972" Approved Supported "Nuclear bodies,Cytosol" "Intracellular and membrane" Transcription NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 21: Early spermatids - Spermatogenesis" 4 "Nuclear bodies, Cytosol" "HPA040402: , HPA041972: AB_2677776" "unprognostic (1.49e-1)" "unprognostic (4.08e-3)" "unprognostic (1.09e-1)" "unprognostic (6.60e-2)" "unprognostic (7.39e-2)" "unprognostic (1.45e-1)" "unprognostic (3.05e-3)" "unprognostic (1.22e-1)" "unprognostic (2.74e-2)" "unprognostic (2.70e-1)" "unprognostic (8.71e-2)" "unprognostic (3.03e-1)" "unprognostic (2.36e-2)" "unprognostic (1.83e-2)" "unprognostic (3.65e-1)" "unprognostic (1.02e-1)" "unprognostic (2.37e-1)" SULF1 "hSulf-1, KIAA1077, SULF-1" ENSG00000137573 "Sulfatase 1" Q8IWU6 8 69466624-69660915 "Predicted intracellular proteins" Apoptosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 203.9;Fibroblasts: 48.9;Inhibitory neurons: 61.2;Late spermatids: 127.3;Mesothelial cells: 83.9;Muller glia cells: 136.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 9 "choroid plexus: 387.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 43.8;thyroid cancer: 65.3" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054728 Supported "Intracellular and membrane" Enzyme NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA054728: AB_2682586" "unprognostic (2.89e-2)" "unprognostic (5.07e-2)" "unprognostic (3.87e-2)" "unprognostic (5.30e-2)" "unprognostic (3.60e-2)" "unprognostic (7.62e-2)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" "unprognostic (3.58e-1)" "unprognostic (1.45e-1)" "unprognostic (3.69e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (8.91e-3)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (2.69e-2)" SULF2 "HSULF-2, KIAA1247, SULF-2" ENSG00000196562 "Sulfatase 2" Q8IWU5 20 47656197-47786616 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 135.0;Endometrial stromal cells: 207.4;Granulosa cells: 208.0;Oligodendrocyte precursor cells: 232.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 22.2;classical monocyte: 17.3;intermediate monocyte: 15.7;myeloid DC: 19.5;neutrophil: 26.4;non-classical monocyte: 8.7;plasmacytoid DC: 25.6" "Group enriched" "Detected in many" 78 "dendritic cells: 25.6;granulocytes: 26.4;monocytes: 17.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002325 Approved "Intracellular and membrane" Enzyme NA NA 340000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 62: Connective tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 9: Endometrial stromal cells - Transcription" "HPA002325: AB_1080126" "unprognostic (4.06e-2)" "prognostic unfavorable (6.43e-5)" "unprognostic (4.39e-1)" "unprognostic (8.99e-2)" "unprognostic (2.65e-1)" "unprognostic (9.08e-2)" "unprognostic (1.87e-1)" "unprognostic (2.48e-2)" "unprognostic (1.81e-2)" "unprognostic (3.04e-2)" "unprognostic (1.53e-3)" "unprognostic (1.85e-1)" "prognostic unfavorable (4.02e-4)" "unprognostic (7.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.09e-1)" "unprognostic (7.14e-3)" SUMF1 "FGE, UNQ3037" ENSG00000144455 "Sulfatase modifying factor 1" Q8NBK3 3 3700814-4467273 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038025 Uncertain "Intracellular and membrane" Enzyme NA NA 2800000 "Cluster 29: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 58: Macrophages - Innate immune response" 2 "HPA038025: AB_10675624" "unprognostic (5.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.08e-1)" "unprognostic (8.99e-3)" "unprognostic (5.66e-2)" "unprognostic (1.11e-1)" "unprognostic (8.34e-3)" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (2.65e-2)" "unprognostic (2.28e-1)" "prognostic favorable (4.79e-7)" "unprognostic (5.12e-2)" "unprognostic (2.58e-1)" "unprognostic (1.45e-1)" "unprognostic (7.86e-2)" SUMF2 DKFZp566I1024 ENSG00000129103 "Sulfatase modifying factor 2" Q8NBJ7 7 56064002-56080670 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024040, CAB025743, HPA074892" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" "No annotated function" Yes No 750000 "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 8 "Vesicles, Plasma membrane" "CAB025743: , HPA024040: AB_1857651, HPA074892: " "unprognostic (2.93e-1)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.42e-2)" "prognostic favorable (3.96e-4)" "unprognostic (3.87e-2)" "unprognostic (9.11e-3)" "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.20e-2)" "unprognostic (1.92e-1)" "unprognostic (7.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.74e-2)" "unprognostic (2.64e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.71e-4)" SUSD1 DKFZP761E1824 ENSG00000106868 "Sushi domain containing 1" Q6UWL2 9 112040783-112175297 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 27.4;Kupffer cells: 28.8;monocytes: 29.1;Oligodendrocyte precursor cells: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 11.1;plasmacytoid DC: 44.3" "Group enriched" "Detected in many" 5 "dendritic cells: 44.3;granulocytes: 11.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048554 Approved Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA 2300000 "Cluster 29: Non-specific - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 1: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 58: Macrophages - Innate immune response" Nucleoplasm "HPA048554: AB_2680439" "unprognostic (2.25e-1)" "unprognostic (4.02e-2)" "unprognostic (1.42e-2)" "unprognostic (1.62e-1)" "unprognostic (9.29e-3)" "unprognostic (5.27e-2)" "unprognostic (1.69e-2)" "unprognostic (3.73e-2)" "unprognostic (1.23e-2)" "unprognostic (1.29e-3)" "unprognostic (2.67e-1)" "unprognostic (3.31e-1)" "prognostic favorable (3.63e-6)" "unprognostic (2.14e-3)" "unprognostic (8.38e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" SUSD4 FLJ10052 ENSG00000143502 "Sushi domain containing 4" Q5VX71 1 223220819-223364233 "Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0;esophagus: 49.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.7;Granulosa cells: 73.3;Inhibitory neurons: 85.9;Oligodendrocyte precursor cells: 95.3;Squamous epithelial cells: 78.7;Suprabasal keratinocytes: 49.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 6.8;naive CD4 T-cell: 10.2" "Lineage enriched" "Detected in single" 40 "T-cells: 10.2" "Cancer enhanced" "Detected in many" "breast cancer: 16.1" "Kidney - Ascending Loop of Henle cells, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058296 Uncertain Approved Vesicles "Intracellular and membrane" "Complement pathway" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 29: Forebrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" Vesicles "HPA058296: AB_2683672" "unprognostic (2.90e-1)" "unprognostic (2.90e-3)" "unprognostic (1.27e-3)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (7.53e-3)" "unprognostic (1.82e-3)" "unprognostic (7.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-3)" "unprognostic (1.36e-1)" "unprognostic (6.51e-6)" "unprognostic (3.64e-2)" "unprognostic (5.11e-2)" "unprognostic (3.03e-1)" "unprognostic (7.11e-2)" SVBP "CCDC23, MGC45441" ENSG00000177868 "Small vasohibin binding protein" Q8N300 1 42807052-42817397 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 173.6;Spermatocytes: 166.6;Spermatogonia: 169.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008507 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Secreted to blood" "No annotated function" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 6: Ovarian stromal cells - Transcription" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA008507: AB_2072066" "prognostic favorable (6.33e-4)" "unprognostic (2.68e-2)" "unprognostic (2.91e-1)" "unprognostic (4.60e-2)" "unprognostic (2.05e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (3.15e-2)" "unprognostic (3.35e-3)" "unprognostic (1.59e-2)" "unprognostic (6.73e-3)" "unprognostic (2.16e-1)" "unprognostic (5.37e-3)" "unprognostic (1.17e-3)" "unprognostic (7.07e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" SVEP1 "bA427L11.3, C9orf13, FLJ13529, POLYDOM" ENSG00000165124 "Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1" Q4LDE5 9 110365248-110579880 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.5;placenta: 60.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 99.7;Inhibitory neurons: 48.0;Leydig cells: 42.2;Mesothelial cells: 96.3;Oligodendrocytes: 130.8;Syncytiotrophoblasts: 85.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 10.8;testis cancer: 10.0" "Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1" "Region enhanced" "Detected in some" "cerebellum: 2.8" "Region enriched" "Detected in all" 4 "cerebellum: 29.1" "HPA020610, HPA021520" Enhanced "Intracellular and membrane" "Cell adhesion" NA NA 160000000 "Cluster 58: Placenta - Pregnancy" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA020610: AB_2197021, HPA021520: AB_1855533" "unprognostic (4.47e-2)" "unprognostic (6.01e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-2)" "unprognostic (2.31e-1)" "unprognostic (2.62e-2)" "unprognostic (9.13e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (3.31e-3)" "unprognostic (2.25e-1)" "unprognostic (1.51e-1)" "unprognostic (4.11e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (9.84e-2)" "unprognostic (2.21e-1)" "unprognostic (1.55e-3)" SWSAP1 "C19orf39, FLJ35119, SWS1AP1, ZSWIM7AP1" ENSG00000173928 "SWIM-type zinc finger 7 associated protein 1" Q6NVH7 19 11374666-11376951 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052712 Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" Other NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 48: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" 9 Nucleoplasm Cytosol "HPA052712: AB_2681925" "unprognostic (6.45e-2)" "unprognostic (3.99e-2)" "unprognostic (1.48e-1)" "unprognostic (2.75e-1)" "unprognostic (1.92e-1)" "unprognostic (1.79e-2)" "unprognostic (5.03e-1)" "unprognostic (1.34e-2)" "unprognostic (4.65e-2)" "unprognostic (8.62e-3)" "unprognostic (1.40e-3)" "unprognostic (2.53e-1)" "unprognostic (1.34e-2)" "prognostic favorable (4.07e-4)" "unprognostic (1.61e-1)" "unprognostic (1.78e-1)" "unprognostic (4.18e-3)" SYAP1 "FLJ14495, PRO3113" ENSG00000169895 "Synapse associated protein 1" Q96A49 X 16719612-16765340 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 548.9;monocytes: 849.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000175, HPA000882, HPA048047" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" Other NA NA 13000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 7 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA000175: AB_1080142, HPA000882: AB_2666128, HPA048047: AB_2680240" "unprognostic (4.66e-2)" "unprognostic (2.99e-2)" "unprognostic (1.25e-2)" "unprognostic (5.44e-2)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (9.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.82e-1)" "unprognostic (1.62e-2)" "unprognostic (1.95e-1)" "unprognostic (3.95e-3)" "unprognostic (1.14e-2)" "unprognostic (8.10e-2)" "unprognostic (5.28e-3)" SYCN "FLJ27441, INSSA1, SYL" ENSG00000179751 Syncollin Q0VAF6 19 39202825-39204263 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 999 "pancreas: 27446.4" "Cell type enriched" "Detected in some" 12 "Exocrine glandular cells: 2281.6" "Cancer enriched" "Detected in single" 842 "pancreatic cancer: 369.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Exocrine glandular cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047654 Enhanced "Intracellular and membrane" Other NA NA 920000 "Cluster 15: Pancreas - Proteolysis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA047654: AB_2680112" "unprognostic (8.02e-2)" TAC1 "NKNA, NPK, TAC2" ENSG00000006128 "Tachykinin precursor 1" P20366 7 97732084-97740472 "Predicted secreted proteins" "Neuropeptide, Neurotransmitter" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 229.7" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 71.0;Inhibitory neurons: 95.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "skin cancer: 8.5" "Region enhanced" "Detected in all" "basal ganglia: 560.0" "Region enriched" "Detected in all" 10 "basal ganglia: 511.9" HPA014429 Enhanced "Secreted to blood" Neuropeptide NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 69: Skin cancer - ECM organization" "Cluster 8: Neurons - Neuronal signaling" "HPA014429: AB_1857722" "unprognostic (9.24e-3)" "unprognostic (2.65e-2)" "unprognostic (1.84e-1)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (2.08e-1)" "unprognostic (7.95e-2)" "unprognostic (3.24e-1)" "unprognostic (1.70e-2)" "unprognostic (3.21e-2)" "unprognostic (1.70e-1)" "unprognostic (1.69e-1)" "unprognostic (3.86e-2)" TAC3 "LncZBTB39, LncZBTB39-1:2, NK3, NKB, NKNB, ZNEUROK1" ENSG00000166863 "Tachykinin precursor 3" Q9UHF0 12 57010000-57028883 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 416.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 12.8;Extravillous trophoblasts: 39.3;Fibroblasts: 8.6;Inhibitory neurons: 38.0;Syncytiotrophoblasts: 23.6" "Cancer enriched" "Detected in many" 7 "urothelial cancer: 40.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 12.4" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045919 Supported Supported Approved Vesicles "Secreted in female reproductive system" Neuropeptide NA NA 130000 "Cluster 58: Placenta - Pregnancy" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 1 Vesicles "HPA045919: AB_10960533" "unprognostic (4.53e-2)" "unprognostic (1.97e-2)" "unprognostic (8.41e-2)" "unprognostic (3.00e-2)" "unprognostic (3.61e-2)" "unprognostic (1.76e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "unprognostic (1.34e-1)" "unprognostic (2.03e-1)" "unprognostic (5.28e-2)" "unprognostic (4.71e-14)" "unprognostic (1.58e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" TAC4 "HK-1, PPT-C, Pptc" ENSG00000176358 "Tachykinin precursor 4" Q86UU9 17 49838300-49848069 "Predicted secreted proteins" "Hypotensive agent" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.5;pituitary gland: 4.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.2;Inhibitory neurons: 1.1;Oligodendrocyte precursor cells: 1.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Other NA NA "Cluster 35: Non-specific - Mitochondria" "Cluster 48: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (4.49e-2)" "unprognostic (8.14e-2)" "unprognostic (8.95e-2)" "unprognostic (1.71e-1)" "unprognostic (6.24e-2)" "unprognostic (8.15e-2)" "unprognostic (5.61e-2)" "unprognostic (6.05e-3)" "unprognostic (3.19e-1)" "unprognostic (2.00e-1)" "unprognostic (4.52e-2)" "unprognostic (4.69e-3)" "unprognostic (8.19e-5)" "unprognostic (8.69e-2)" "unprognostic (2.23e-1)" "unprognostic (7.98e-2)" "unprognostic (1.92e-1)" TAFA1 "FAM19A1, TAFA-1" ENSG00000183662 "TAFA chemokine like family member 1" Q7Z5A9 3 68004247-68545621 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 19.0;choroid plexus: 7.0" "Cell type enhanced" "Detected in some" "Astrocytes: 120.1;Excitatory neurons: 573.2;Oligodendrocyte precursor cells: 289.1" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 7.6;MAIT T-cell: 4.8;memory CD4 T-cell: 5.6;memory CD8 T-cell: 4.4;naive CD4 T-cell: 4.1;naive CD8 T-cell: 5.4;T-reg: 2.8" "Lineage enriched" "Detected in many" 8 "T-cells: 7.6" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 19.9;cerebral cortex: 55.9;hippocampal formation: 52.2" HPA013407 Approved "Secreted in brain" "No annotated function" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA013407: AB_1848386" "unprognostic (5.19e-2)" "unprognostic (4.64e-3)" "unprognostic (1.97e-2)" "unprognostic (1.86e-2)" "unprognostic (7.95e-2)" "unprognostic (6.40e-2)" "unprognostic (3.42e-3)" "unprognostic (1.79e-1)" "unprognostic (1.20e-1)" "unprognostic (2.41e-1)" "unprognostic (1.41e-2)" "unprognostic (7.87e-2)" "unprognostic (1.35e-3)" "unprognostic (2.11e-1)" "unprognostic (1.99e-1)" "unprognostic (3.50e-4)" "unprognostic (5.77e-2)" TAFA2 "FAM19A2, TAFA-2" ENSG00000198673 "TAFA chemokine like family member 2" Q8N3H0 12 61708273-62279150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7" "Group enriched" "Detected in many" 4 "Early spermatids: 182.3;Excitatory neurons: 638.4;Inhibitory neurons: 668.1;Oligodendrocyte precursor cells: 599.5" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 31.7;neutrophil: 12.1" "Lineage enriched" "Detected in many" 8 "granulocytes: 31.7" "Cancer enhanced" "Detected in some" "Bone cancer: 3.7;Leukemia: 5.2" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" "No annotated function" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 33: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 8: Neurons - Neuronal signaling" "unprognostic (3.89e-3)" "unprognostic (9.33e-2)" "unprognostic (1.02e-1)" "unprognostic (1.37e-2)" "unprognostic (2.78e-1)" "unprognostic (4.83e-1)" "unprognostic (6.62e-2)" "unprognostic (4.16e-3)" "unprognostic (4.08e-1)" "unprognostic (1.80e-1)" "unprognostic (3.22e-5)" "unprognostic (1.05e-1)" "unprognostic (2.22e-2)" "unprognostic (3.31e-2)" "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (1.28e-1)" TAFA3 "FAM19A3, TAFA-3" ENSG00000184599 "TAFA chemokine like family member 3" Q7Z5A8 1 112718905-112727235 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 13.2;retina: 44.5" "Cell type enriched" "Detected in some" 4 "Cone photoreceptor cells: 185.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Rhabdoid: 14.0;skin cancer: 4.5" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 21 "olfactory bulb: 3.5" "Low region specificity" "Detected in all" HPA055927 Approved "Secreted in other tissues" "No annotated function" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "HPA055927: AB_2682972" "unprognostic (9.96e-2)" "unprognostic (4.30e-1)" "unprognostic (3.36e-2)" "unprognostic (5.63e-4)" "prognostic unfavorable (9.60e-4)" "unprognostic (1.66e-1)" "unprognostic (3.40e-2)" "unprognostic (1.13e-1)" "unprognostic (6.43e-2)" "unprognostic (1.32e-1)" "unprognostic (9.82e-2)" "unprognostic (2.51e-1)" "unprognostic (5.14e-6)" "unprognostic (2.10e-4)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-1)" TAFA4 "FAM19A4, TAFA-4" ENSG00000163377 "TAFA chemokine like family member 4" Q96LR4 3 68731766-68953297 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 14.5;brain: 6.9;retina: 10.8;stomach 1: 4.7" "Group enriched" "Detected in some" 4 "Bipolar cells: 35.5;Cone photoreceptor cells: 51.0;Inhibitory neurons: 34.2;Oligodendrocytes: 55.8;Oocytes: 61.0" "Cancer enhanced" "Detected in some" "testis cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "testis cancer: 2.3" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 5 "thalamus: 13.5" "Low region specificity" "Detected in many" "Secreted in brain" "No annotated function" NA NA "Cluster 76: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 8: Neurons - Neuronal signaling" 1 "unprognostic (1.92e-1)" "unprognostic (9.97e-3)" "unprognostic (2.28e-1)" "unprognostic (8.19e-3)" "unprognostic (8.78e-2)" "unprognostic (2.00e-2)" "unprognostic (3.01e-2)" "unprognostic (1.22e-1)" "unprognostic (3.66e-2)" "unprognostic (8.06e-2)" "unprognostic (2.50e-1)" TAFA5 "FAM19A5, TAFA-5" ENSG00000219438 "TAFA chemokine like family member 5" Q7Z5A7 22 48489553-48850912 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 82.8" "Cell type enhanced" "Detected in many" "Astrocytes: 62.2;Endometrial stromal cells: 32.3;Excitatory neurons: 46.8;Inhibitory neurons: 74.0;Muller glia cells: 34.8;Oligodendrocyte precursor cells: 57.1;Oligodendrocytes: 43.4;Schwann cells: 54.0" "Cancer enhanced" "Detected in all" "glioma: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bone cancer: 33.2;Neuroblastoma: 20.1" "Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025629 Approved "Secreted in brain" Cytokine NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 10: Muller glia cells - Visual perception" "CAB025629: " "unprognostic (2.86e-1)" "unprognostic (2.98e-1)" "unprognostic (3.42e-2)" "unprognostic (2.19e-1)" "unprognostic (3.57e-1)" "unprognostic (1.80e-1)" "unprognostic (2.82e-3)" "unprognostic (2.41e-2)" "unprognostic (6.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-2)" "unprognostic (1.26e-1)" "unprognostic (9.31e-3)" "unprognostic (2.64e-2)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.94e-2)" TAGLN2 "HA1756, KIAA0120" ENSG00000158710 "Transgelin 2" P37802 1 159918107-159925507 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2828.0;Pancreatic endocrine cells: 1344.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001925 Approved Approved "Actin filaments,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 270000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Platelets - Hemostasis" 4 Cytosol "Actin filaments" "HPA001925: AB_1857756" "prognostic unfavorable (2.06e-5)" "unprognostic (2.56e-1)" "unprognostic (4.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.69e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (7.07e-5)" "unprognostic (4.61e-2)" "unprognostic (1.50e-1)" "unprognostic (3.21e-1)" "unprognostic (3.56e-3)" "unprognostic (2.34e-1)" "prognostic unfavorable (1.92e-10)" "unprognostic (1.81e-1)" "unprognostic (9.22e-2)" "unprognostic (3.95e-2)" "unprognostic (2.50e-2)" TBL2 "DKFZP43N024, WBSCR13, WS-betaTRP" ENSG00000106638 "Transducin beta like 2" Q9Y4P3 7 73567537-73578791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 18.8" "Group enriched" "Detected in many" 7 "Early spermatids: 424.7;Late spermatids: 514.3;Spermatocytes: 295.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007477, HPA051533" Supported Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 46: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 31: Spermatocytes - Spermatogenesis" Cytosol "HPA007477: AB_1080214, HPA051533: AB_2681523" "unprognostic (9.04e-2)" "unprognostic (6.61e-3)" "unprognostic (4.24e-2)" "unprognostic (1.10e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.24e-3)" "unprognostic (7.50e-2)" "unprognostic (2.87e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.88e-5)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (1.42e-2)" "unprognostic (1.31e-1)" TBX10 "TBX13, TBX7" ENSG00000167800 "T-box transcription factor 10" O75333 11 67631303-67639763 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "intestine: 8.2" "Group enriched" "Detected in some" 16 "Intestinal goblet cells: 113.9;Proximal enterocytes: 44.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Colon - Colon enterocytes, Liver - Hepatocytes" "Low region specificity" "Detected in single" "HPA047881, HPA076197" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" Transcription NA NA "Cluster 45: Intestine - Digestion" "Cluster 70: DU4475 - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm Cytosol "HPA047881: AB_2680199, HPA076197: " "unprognostic (4.66e-2)" "unprognostic (2.96e-2)" "unprognostic (7.71e-3)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (1.83e-4)" "unprognostic (3.12e-1)" "unprognostic (3.29e-2)" "unprognostic (5.10e-2)" "unprognostic (1.83e-1)" "unprognostic (4.90e-1)" "unprognostic (1.17e-10)" "unprognostic (6.77e-2)" "unprognostic (1.68e-1)" "unprognostic (2.95e-1)" "unprognostic (2.75e-1)" TCN1 "TC1, TCI" ENSG00000134827 "Transcobalamin 1" P20061 11 59852800-59866489 "Plasma proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 188.9;gallbladder: 167.7;salivary gland: 753.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 78.2;Club cells: 74.5;Exocrine glandular cells: 190.8;Glandular and luminal cells: 107.6;Mucus glandular cells: 366.5;Serous glandular cells: 239.1" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 124.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 149 "basophil: 2379.0" "Lineage enriched" "Detected in many" 1591 "granulocytes: 2379.0" "Cancer enhanced" "Detected in many" "Bile duct cancer: 62.4;breast cancer: 36.3;ovarian cancer: 40.4" "Lung - Neutrophil_1, Pancreas - Ductal cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Secreted to blood" Transport NA NA 4000000 "Cluster 46: Basophils - Proteolysis" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 66: Non-specific - Mitochondria" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "prognostic favorable (1.90e-4)" "unprognostic (1.17e-1)" "unprognostic (5.89e-2)" "unprognostic (3.61e-3)" "unprognostic (2.49e-2)" "unprognostic (5.28e-3)" "unprognostic (4.52e-3)" "unprognostic (3.11e-3)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (9.07e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.56e-8)" "unprognostic (2.50e-1)" "unprognostic (8.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" TCN2 "D22S676, D22S750, TC2" ENSG00000185339 "Transcobalamin 2" P20062 22 30607003-30627271 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 111.7" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 552.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 43.3;intermediate monocyte: 66.4;non-classical monocyte: 23.9" "Lineage enriched" "Detected in many" 9 "monocytes: 66.4" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Lung - Macrophages, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000837 Approved Cytosol "Secreted to blood" Transport NA NA 19000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 52: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 22: Proximal enterocytes - Digestion" 1 Cytosol "HPA000837: AB_1080235" "unprognostic (6.43e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.53e-3)" "unprognostic (3.17e-1)" "unprognostic (1.49e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.64e-4)" "unprognostic (1.52e-2)" "unprognostic (2.90e-1)" "unprognostic (1.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.59e-1)" "unprognostic (6.95e-3)" "unprognostic (4.94e-3)" "unprognostic (2.09e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" TCTN1 "FLJ21127, JBTS13, TECT1" ENSG00000204852 "Tectonic family member 1" Q2MV58 12 110614027-110663431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 162.2;Early spermatids: 103.0;Spermatocytes: 111.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039687, HPA040036" Approved Approved "Nucleoplasm,Actin filaments" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" 1 "Nucleoplasm, Actin filaments" "HPA039687: AB_10795293, HPA040036: AB_10794759" "unprognostic (2.54e-1)" "unprognostic (7.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (1.13e-5)" "unprognostic (2.89e-2)" "unprognostic (6.53e-2)" "unprognostic (2.11e-1)" "unprognostic (3.05e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (9.60e-2)" "unprognostic (9.97e-2)" "unprognostic (2.15e-2)" "unprognostic (8.41e-2)" "unprognostic (1.24e-1)" "unprognostic (4.27e-2)" TCTN3 "C10orf61, DKFZP564D116, JBTS18, TECT3" ENSG00000119977 "Tectonic family member 3" Q6NUS6 10 95659823-95694143 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026987 Approved Approved Microtubules "Intracellular and membrane" Other NA NA 4400000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 28: Dendritic cells - Antigen presentation" Microtubules "HPA026987: AB_10600911" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "unprognostic (9.78e-2)" "prognostic favorable (5.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.50e-2)" "unprognostic (8.88e-3)" "unprognostic (1.08e-1)" "unprognostic (3.03e-2)" "unprognostic (9.25e-3)" "unprognostic (3.78e-3)" "unprognostic (7.29e-2)" "unprognostic (4.60e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (9.30e-3)" "unprognostic (1.59e-1)" TDGF1 "CR, CR-1, CRIPTO, Cripto-1" ENSG00000241186 "Teratocarcinoma-derived growth factor 1" P13385 3 46574534-46582457 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 22.8;lymphoid tissue: 20.4;ovary: 9.2" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 92.2" "Cancer enriched" "Detected in many" 4 "testis cancer: 27.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 61.0" "Group enriched" "Detected in many" 5 "cerebellum: 11.2;pons and medulla: 8.7" HPA051928 Approved Vesicles "Secreted in other tissues" "Growth factor" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 6: Ovarian stromal cells - Transcription" Vesicles "HPA051928: " "unprognostic (7.84e-3)" "unprognostic (2.00e-2)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.93e-1)" "unprognostic (3.61e-1)" "unprognostic (1.72e-2)" "unprognostic (6.77e-2)" "unprognostic (1.74e-1)" "unprognostic (8.76e-3)" "unprognostic (2.01e-1)" "unprognostic (2.10e-2)" "unprognostic (1.75e-2)" "unprognostic (1.05e-1)" TDP2 TTRAP ENSG00000111802 "Tyrosyl-DNA phosphodiesterase 2" O95551 6 24649979-24666930 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" "Hydrolase, Nuclease" "Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 178.2" "Cell type enhanced" "Detected in all" "Distal enterocytes: 604.3;Paneth cells: 462.3;Proximal enterocytes: 607.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 75.8;neutrophil: 229.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 229.6" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB073398, HPA074011" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Enzyme No No "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 6 "Nucleoplasm, Nuclear bodies" "CAB073398: , HPA074011: AB_2686651" "unprognostic (2.46e-2)" "unprognostic (2.10e-3)" "unprognostic (1.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.58e-1)" "unprognostic (4.66e-3)" "unprognostic (4.13e-3)" "unprognostic (3.24e-1)" "unprognostic (5.78e-3)" "prognostic favorable (2.53e-7)" "unprognostic (1.20e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (1.40e-2)" "unprognostic (1.42e-1)" "unprognostic (9.70e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.47e-5)" TECTA "DFNA12, DFNA8, DFNB21" ENSG00000109927 "Tectorin alpha" O75443 11 121101243-121191490 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Astrocytes: 5.0;Early spermatids: 3.8;Excitatory neurons: 9.5;Inhibitory neurons: 6.9;Late spermatids: 3.6;Oligodendrocyte precursor cells: 4.7;Oocytes: 3.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Sarcoma: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA018870 Approved "Secreted in other tissues" Other NA NA "Cluster 28: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 34: Neurons - Neuronal signaling" "HPA018870: AB_1857879" "unprognostic (1.12e-3)" "unprognostic (2.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.45e-2)" "unprognostic (4.30e-2)" "unprognostic (3.11e-1)" "unprognostic (3.00e-2)" "unprognostic (3.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.14e-1)" "unprognostic (1.39e-6)" "unprognostic (1.22e-1)" "unprognostic (4.15e-3)" "unprognostic (6.97e-3)" "unprognostic (1.12e-1)" "unprognostic (3.28e-2)" "unprognostic (4.19e-2)" TECTB ENSG00000119913 "Tectorin beta" Q96PL2 10 112283400-112305038 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "Late spermatids: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted in other tissues" "No annotated function" NA NA "Cluster 56: Non-specific - Sensory perception" "Cluster 11: Late spermatids - Unknown function" "unprognostic (3.14e-2)" "unprognostic (2.84e-2)" "unprognostic (9.75e-3)" "unprognostic (1.65e-1)" "unprognostic (1.32e-2)" "unprognostic (5.54e-2)" "unprognostic (2.80e-2)" "unprognostic (8.10e-2)" TEDC1 C14orf80 ENSG00000185347 "Tubulin epsilon and delta complex 1" Q86SX3 14 105489855-105499575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 29.3;Gastric mucus-secreting cells: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA039049, HPA039050" Uncertain Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" "No annotated function" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 33: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Non-specific - Basic cellular processes" 1 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039049: AB_2676320, HPA039050: AB_10670918" "unprognostic (8.06e-2)" "unprognostic (1.06e-2)" "unprognostic (9.17e-2)" "unprognostic (1.65e-1)" "unprognostic (3.06e-1)" "unprognostic (1.57e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (5.19e-2)" "unprognostic (1.49e-1)" "unprognostic (3.12e-1)" "unprognostic (3.81e-2)" "unprognostic (2.91e-2)" "unprognostic (1.12e-3)" "unprognostic (8.73e-3)" "unprognostic (2.88e-1)" "unprognostic (1.17e-1)" "unprognostic (6.18e-3)" TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.7" "Group enriched" "Detected in some" 6 "Adipocytes: 67.0;Endothelial cells: 74.2;Lymphatic endothelial cells: 34.9;Microglial cells: 36.7;Oligodendrocyte precursor cells: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Rhabdoid: 17.5;testis cancer: 16.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" Receptor NA NA 7750000 13000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" TENT5B "FAM46B, MGC16491" ENSG00000158246 "Terminal nucleotidyltransferase 5B" Q96A09 1 27005020-27012850 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 108.6;skin 1: 117.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.1;Basal keratinocytes: 106.0;Basal squamous epithelial cells: 82.2;Squamous epithelial cells: 157.1;Suprabasal keratinocytes: 213.2" "Cancer enhanced" "Detected in many" "testis cancer: 87.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Intracellular and membrane" Enzyme NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 57 "unprognostic (1.67e-2)" "unprognostic (5.94e-3)" "unprognostic (1.61e-1)" "unprognostic (5.28e-3)" "unprognostic (3.20e-2)" "unprognostic (2.22e-2)" "unprognostic (2.44e-4)" "unprognostic (4.05e-2)" "unprognostic (1.39e-1)" "unprognostic (6.02e-3)" "unprognostic (1.34e-1)" "unprognostic (1.11e-1)" "unprognostic (1.00e-1)" "unprognostic (5.82e-2)" "unprognostic (4.85e-2)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" TEPP ENSG00000159648 "Testis, prostate and placenta expressed" Q6URK8 16 57976435-57988116 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 13.8" "Group enriched" "Detected in many" 17 "Early spermatids: 297.0;Late spermatids: 460.0" "Group enriched" "Detected in some" 4 "thyroid cancer: 3.2;urothelial cancer: 1.5" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Not detected" "Not detected" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA062092 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 11: Late spermatids - Unknown function" "HPA062092: AB_2684679" "unprognostic (4.86e-2)" "unprognostic (2.72e-1)" "unprognostic (4.12e-2)" "unprognostic (2.56e-2)" "unprognostic (1.79e-2)" "unprognostic (8.04e-2)" "unprognostic (3.67e-1)" "unprognostic (2.40e-2)" "unprognostic (2.74e-1)" "unprognostic (2.48e-1)" "unprognostic (1.52e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.46e-1)" "unprognostic (3.97e-3)" "unprognostic (2.59e-1)" TEX101 "CT131, MGC4766, SGRG, SPATA44, TES101RP" ENSG00000131126 "Testis expressed 101" Q9BY14 19 43401496-43418597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 73 "testis: 114.4" "Cell type enriched" "Detected in some" 11 "Spermatocytes: 950.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 5 "cerebral cortex: 45.4" "Immune cell enriched" "Detected in single" 557 "basophil: 55.7" "Lineage enriched" "Detected in single" 557 "granulocytes: 55.7" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041915, HPA042513" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA041915: AB_10795268, HPA042513: AB_10795507" "unprognostic (2.50e-2)" "unprognostic (5.67e-4)" "unprognostic (2.64e-1)" "unprognostic (6.89e-2)" "unprognostic (1.87e-1)" "unprognostic (5.78e-4)" "unprognostic (1.70e-1)" "unprognostic (2.84e-2)" "unprognostic (6.54e-2)" "unprognostic (4.06e-1)" "unprognostic (2.49e-2)" "unprognostic (1.67e-7)" "unprognostic (8.83e-2)" "unprognostic (2.24e-1)" "unprognostic (7.49e-2)" "unprognostic (7.04e-2)" TEX264 "FLJ13935, ZSIG11" ENSG00000164081 "Testis expressed 264, ER-phagy receptor" Q9Y6I9 3 51662693-51704323 "Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 351.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005002, HPA017739, HPA073223" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 23 "Endoplasmic reticulum" "CAB005002: AB_425976, HPA017739: AB_1857910, HPA073223: " "unprognostic (2.80e-3)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (2.79e-3)" "unprognostic (8.11e-2)" "unprognostic (8.26e-3)" "unprognostic (2.05e-1)" "unprognostic (3.06e-3)" "unprognostic (2.30e-1)" "unprognostic (5.19e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.83e-1)" "prognostic favorable (7.95e-9)" "unprognostic (4.99e-2)" "unprognostic (3.65e-1)" "unprognostic (3.17e-1)" "unprognostic (4.67e-2)" TF "PRO1557, PRO2086" ENSG00000091513 Transferrin P02787 3 133746040-133796641 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Ion transport, Iron transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1466.9;liver: 7278.6;retina: 2358.0" "Group enriched" "Detected in many" 8 "Hepatocytes: 5785.8;Muller glia cells: 10733.8" "Cancer enriched" "Detected in many" 42 "liver cancer: 783.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "liver cancer: 221.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Enteric glia cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001527, HPA005692, CAB009538" Enhanced "Secreted to blood" Transport NA NA 19800000000000 98000000000 "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 10: Muller glia cells - Visual perception" 20 "CAB009538: AB_793365, HPA001527: AB_1080357, HPA005692: AB_1080354" "prognostic favorable (4.05e-4)" "unprognostic (2.45e-2)" "unprognostic (1.78e-1)" "unprognostic (1.50e-1)" "unprognostic (8.99e-2)" "unprognostic (5.18e-2)" "unprognostic (6.63e-2)" "unprognostic (8.46e-2)" "unprognostic (2.82e-1)" "unprognostic (3.08e-1)" "unprognostic (1.37e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (2.35e-13)" "unprognostic (2.17e-3)" "unprognostic (5.49e-2)" "unprognostic (3.47e-3)" "unprognostic (9.70e-2)" TFAM "TCF6, TCF6L2" ENSG00000108064 "Transcription factor A, mitochondrial" Q00059 10 58385345-58399220 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 327.0;Late spermatids: 1051.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040648, HPA063684" Supported Enhanced Mitochondria "Intracellular and membrane" Transcription NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Testis - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 11: Late spermatids - Unknown function" 8 Mitochondria "HPA040648: AB_10795635, HPA063684: AB_2685089" "unprognostic (5.30e-2)" "unprognostic (1.14e-1)" "unprognostic (6.34e-3)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.10e-2)" "unprognostic (3.40e-2)" "unprognostic (1.54e-2)" "unprognostic (3.23e-2)" "unprognostic (1.24e-2)" "prognostic favorable (2.74e-4)" "unprognostic (1.99e-2)" "unprognostic (5.39e-2)" "prognostic favorable (2.22e-5)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (6.76e-2)" TFF1 "BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2" ENSG00000160182 "Trefoil factor 1" P04155 21 42362282-42366535 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "stomach 1: 7747.8" "Group enriched" "Detected in many" 8 "Gastric mucus-secreting cells: 10966.3;Intestinal goblet cells: 2798.0" "Group enriched" "Detected in many" 10 "breast cancer: 402.1;colorectal cancer: 268.3;pancreatic cancer: 805.7;stomach cancer: 744.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 10 "breast cancer: 1444.6" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002170, HPA003425" Enhanced "Secreted to digestive system" "Growth factor" NA NA 950000 "Cluster 48: Stomach - Proteolysis" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 9 "CAB002170: AB_563985, HPA003425: AB_1848260" "prognostic favorable (5.00e-4)" "unprognostic (8.81e-3)" "unprognostic (9.82e-2)" "prognostic favorable (5.67e-4)" "unprognostic (2.42e-1)" "unprognostic (1.72e-3)" "unprognostic (8.14e-2)" "unprognostic (2.45e-1)" "unprognostic (1.52e-1)" "unprognostic (6.62e-2)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (7.72e-3)" "unprognostic (1.07e-1)" TFF2 SML1 ENSG00000160181 "Trefoil factor 2" Q03403 21 42346357-42350997 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 6663.4" "Group enriched" "Detected in some" 56 "Cholangiocytes: 2367.6;Gastric mucus-secreting cells: 6670.8" "Group enriched" "Detected in many" 11 "pancreatic cancer: 320.9;stomach cancer: 244.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Gastric cancer: 75.2;pancreatic cancer: 79.8" "Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025834, HPA036705" Enhanced "Secreted to digestive system" "No annotated function" NA NA 890000 "Cluster 48: Stomach - Proteolysis" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 46: Gastric mucus-secreting cells - Digestion" 8 "CAB025834: , HPA036705: AB_2675263" "unprognostic (3.95e-2)" "unprognostic (9.87e-2)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.89e-2)" "unprognostic (5.55e-2)" "unprognostic (1.27e-9)" "unprognostic (1.99e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-1)" "unprognostic (5.26e-3)" TFF3 "HITF, ITF" ENSG00000160180 "Trefoil factor 3" Q07654 21 42311667-42315409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 445.6;intestine: 526.1;salivary gland: 330.1;thyroid gland: 426.6" "Cell type enriched" "Detected in many" 19 "Intestinal goblet cells: 56202.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 765.0" "Region enriched" "Detected in single" 6 "midbrain: 4.6" "Immune cell enriched" "Detected in single" 16 "eosinophil: 1.6" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.6" "Cancer enhanced" "Detected in many" "breast cancer: 357.7;colorectal cancer: 184.6" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Smooth muscle cells" "Region enriched" "Detected in single" 15 "cerebellum: 1.5" "Not detected" "Not detected" "CAB020681, HPA035464" Enhanced Approved Nucleoplasm,Nucleoli "Secreted to blood" "No annotated function" No NA 151000000 6500000 "Cluster 45: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 3 Nucleoplasm Nucleoli "CAB020681: , HPA035464: AB_2674636" "unprognostic (2.84e-2)" "unprognostic (3.61e-3)" "unprognostic (1.07e-1)" "prognostic favorable (5.60e-6)" "unprognostic (1.28e-1)" "unprognostic (2.35e-2)" "unprognostic (2.13e-1)" "unprognostic (5.03e-2)" "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (3.71e-1)" "unprognostic (6.90e-2)" "unprognostic (4.31e-2)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" "unprognostic (3.86e-2)" TFPI "EPI, LACI, TFI, TFPI1" ENSG00000003436 "Tissue factor pathway inhibitor" P10646 2 187464230-187565760 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 263.9;placenta: 184.8" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 2784.0;Lymphatic endothelial cells: 1775.9;Syncytiotrophoblasts: 976.8" "Cancer enhanced" "Detected in all" "liver cancer: 22.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA005575, CAB020842" Supported "Secreted to blood" "Blood coagulation" NA NA 58100000 87000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 4: Extravillous trophoblasts - Unknown function" "CAB020842: , HPA005575: AB_1080290" "unprognostic (8.75e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (7.95e-2)" "unprognostic (4.99e-2)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (5.63e-2)" "unprognostic (3.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.43e-2)" "unprognostic (2.72e-2)" "unprognostic (7.05e-2)" "unprognostic (3.39e-3)" "unprognostic (4.05e-2)" "unprognostic (4.49e-2)" "unprognostic (5.81e-2)" TFPI2 "PP5, REF1, TFPI-2" ENSG00000105825 "Tissue factor pathway inhibitor 2" P48307 7 93885396-93890753 "Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "placenta: 925.7" "Cell type enhanced" "Detected in many" "Ductal cells: 1324.1;Glandular and luminal cells: 546.5;Pancreatic endocrine cells: 436.4;Secretory cells: 451.4;Syncytiotrophoblasts: 2021.1" "Cancer enhanced" "Detected in all" "renal cancer: 65.9" "Region enhanced" "Detected in many" "medulla oblongata: 10.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "thyroid cancer: 919.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Mesothelial cells, Liver - Vascular Endothelial cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 40.4" "CAB010142, HPA049158, HPA070525" Enhanced "Secreted to extracellular matrix" "Blood coagulation" NA NA 51000 "Cluster 58: Placenta - Pregnancy" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "CAB010142: AB_628166, HPA049158: AB_2680659, HPA070525: " "prognostic favorable (8.33e-7)" "unprognostic (2.20e-2)" "unprognostic (2.10e-2)" "prognostic favorable (5.42e-4)" "unprognostic (5.19e-3)" "unprognostic (3.98e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-2)" "unprognostic (1.15e-2)" "unprognostic (6.86e-2)" "unprognostic (7.54e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (3.38e-3)" "unprognostic (3.65e-2)" "unprognostic (1.97e-1)" "unprognostic (7.91e-2)" TFRC "CD71, p90, TFR1" ENSG00000072274 "Transferrin receptor" P02786 3 196012511-196082153 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 451.2;monocytes: 612.3;Syncytiotrophoblasts: 467.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000153, HPA028598" Enhanced Supported Endosomes,Lysosomes "Secreted to blood" Receptor NA NA 1310000000 38000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 56: Non-specific - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" 23 "Endosomes, Lysosomes" "CAB000153: AB_2533029, HPA028598: AB_10601599" "unprognostic (2.95e-2)" "prognostic unfavorable (3.67e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" "unprognostic (6.75e-2)" "unprognostic (7.88e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.92e-2)" "unprognostic (3.30e-3)" "unprognostic (4.35e-2)" "unprognostic (1.34e-2)" "unprognostic (1.14e-2)" "unprognostic (3.63e-3)" "unprognostic (3.65e-2)" "unprognostic (1.19e-2)" "prognostic unfavorable (2.96e-4)" "unprognostic (2.62e-2)" TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 689 "thyroid gland: 9062.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 10.9;Proximal tubular cells: 3.7;Salivary duct cells: 8.7" "Cancer enriched" "Detected in some" 1672 "thyroid cancer: 3072.8" "Group enriched" "Detected in some" 4 "amygdala: 5.8;cerebral cortex: 3.8;choroid plexus: 3.1;hippocampal formation: 3.3" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 9 "thyroid cancer: 16.6" "Prostate - Prostate basal glandular cells, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in many" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" Hormone NA NA 1600000 "Cluster 4: Neutrophils - Degranulation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 "CAB000077: , CAB056155: AB_2665573, HPA002740: AB_1080277" "unprognostic (1.18e-1)" "unprognostic (6.86e-2)" "unprognostic (7.40e-4)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (7.38e-2)" "unprognostic (4.96e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (5.11e-2)" "unprognostic (3.64e-2)" TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.7" "Cell type enhanced" "Detected in many" "Ductal cells: 31.3;Early spermatids: 30.9;Oligodendrocyte precursor cells: 55.7;Oligodendrocytes: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.4;eosinophil: 23.9;neutrophil: 24.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 24.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 179.0" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042297 Approved Approved Vesicles "Secreted to blood" "Growth factor" No No 57900 "Cluster 21: Neutrophils - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 3 Vesicles "HPA042297: AB_10793878" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (3.57e-3)" "unprognostic (6.39e-2)" "unprognostic (1.41e-1)" "unprognostic (8.49e-3)" "unprognostic (1.52e-1)" "unprognostic (3.00e-3)" "unprognostic (6.69e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (7.74e-2)" "unprognostic (3.70e-2)" "unprognostic (1.60e-1)" "unprognostic (9.21e-2)" "prognostic favorable (1.52e-4)" "unprognostic (9.19e-2)" TGFB1 "CED, DPD1, TGFB, TGFbeta" ENSG00000105329 "Transforming growth factor beta 1" 19 41301587-41353922 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 292.5;Extravillous trophoblasts: 513.7;monocytes: 202.5;NK-cells: 427.9;T-cells: 220.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000361, HPA073356" Approved Approved "Golgi apparatus,Cytosol" "Secreted to blood" NA NA 1290000 "Cluster 45: Eosinophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Golgi apparatus" Cytosol "CAB000361: AB_2201910, HPA073356: " "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (3.29e-2)" "unprognostic (4.90e-2)" "unprognostic (3.75e-3)" "prognostic unfavorable (3.38e-4)" "unprognostic (8.51e-3)" "unprognostic (5.63e-3)" "unprognostic (2.47e-2)" "unprognostic (5.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (1.19e-8)" "unprognostic (1.65e-3)" "unprognostic (2.79e-2)" "unprognostic (6.39e-2)" "unprognostic (4.86e-3)" TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 113.0;Mucus glandular cells: 95.6;Muller glia cells: 46.3;Salivary duct cells: 77.3" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 89.1" "Breast - Breast myoepithelial cells, Pancreas - Ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" "Growth factor" NA Yes 4890000 "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 47: Astrocytes - Unknown function" 1 Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 20.5;Late spermatids: 53.6;Leydig cells: 27.0;Prostatic glandular cells: 26.2;Smooth muscle cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 23.8" "Heart muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063582 Approved Vesicles "Secreted to blood" "Growth factor" NA NA 44800 "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 2 Vesicles "HPA063582: AB_2685049" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (4.32e-3)" "unprognostic (1.29e-1)" "unprognostic (3.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.79e-2)" "unprognostic (2.83e-2)" "unprognostic (1.51e-2)" "unprognostic (5.63e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (4.01e-7)" "unprognostic (6.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (3.27e-3)" TGFBI "BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1" ENSG00000120708 "Transforming growth factor beta induced" Q15582 5 136028988-136063818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Sensory transduction, Vision" "Amyloidosis, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 483.5;placenta: 441.9" "Cell type enhanced" "Detected in many" "dendritic cells: 338.1;Fibroblasts: 238.4;Hofbauer cells: 278.0;Kupffer cells: 248.0;Langerhans cells: 259.0;Macrophages: 234.9;Pancreatic endocrine cells: 728.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 7 "choroid plexus: 87.4;thalamus: 150.1" "Group enriched" "Detected in many" 32 "classical monocyte: 252.5;intermediate monocyte: 149.2;myeloid DC: 157.2;non-classical monocyte: 121.9;plasmacytoid DC: 325.2" "Group enriched" "Detected in all" 46 "dendritic cells: 325.2;monocytes: 252.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 2635.3" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008612, HPA017019" Enhanced "Secreted to blood" "Cell adhesion" NA NA 1600000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 4 "HPA008612: AB_1857970, HPA017019: AB_2669511" "unprognostic (1.05e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.38e-3)" "prognostic favorable (1.17e-4)" "unprognostic (5.21e-3)" "unprognostic (5.53e-3)" "unprognostic (4.60e-2)" "unprognostic (8.71e-3)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.42e-3)" "unprognostic (2.26e-1)" "prognostic unfavorable (7.82e-10)" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (3.42e-1)" "unprognostic (1.70e-3)" TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 143.6;Early spermatids: 120.9;Late spermatids: 121.3;Microglial cells: 110.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 123.2" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 28: Dendritic cells - Antigen presentation" 3 "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: AB_2683144" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 389.3;Endothelial cells: 383.4;Fibroblasts: 209.7;Lymphatic endothelial cells: 308.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" "Secreted to blood" Receptor NA NA 810000 "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 54 "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" TGFBR3 "betaglycan, BGCAN" ENSG00000069702 "Transforming growth factor beta receptor 3" Q03167 1 91680343-91906335 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 143.4;Endothelial cells: 124.4;Fibroblasts: 171.7;Leydig cells: 144.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 35.3;MAIT T-cell: 19.5;memory CD4 T-cell: 8.9;memory CD8 T-cell: 19.2;naive CD8 T-cell: 12.8;NK-cell: 16.7" "Group enriched" "Detected in many" 18 "NK-cells: 16.7;T-cells: 35.3" "Cancer enriched" "Detected in many" 6 "Gallbladder cancer: 73.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008257, CAB018971" Supported Approved Cytosol "Secreted to blood" Receptor NA NA 50000000 "Cluster 15: NK-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 Cytosol "CAB018971: , HPA008257: AB_1080258" "unprognostic (7.57e-2)" "unprognostic (3.67e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.36e-4)" "unprognostic (9.39e-3)" "prognostic favorable (4.84e-4)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (1.07e-1)" "prognostic favorable (4.99e-4)" "unprognostic (2.46e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (1.08e-2)" TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127385-38166578 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 418.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 200.2;Cytotrophoblasts: 303.9;Ductal cells: 230.4;Endometrial stromal cells: 469.5;Endothelial cells: 214.2;Smooth muscle cells: 197.2;Syncytiotrophoblasts: 346.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 424.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Enzyme Yes No 1700000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 62: Connective tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Smooth muscle cells - Muscle contraction" 5 Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" THBS1 "THBS, THBS-1, TSP, TSP-1, TSP1" ENSG00000137801 "Thrombospondin 1" P07996 15 39581079-39599466 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion, Inflammatory response, Unfolded protein response" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 678.5;monocytes: 1951.1;Mucus glandular cells: 699.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 15.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 27.1" "CAB033678, HPA059756" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 16000000000 1400000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 29: Monocytes - Innate immune response" 2 "Plasma membrane" "CAB033678: AB_793044, HPA059756: AB_2684121" "unprognostic (1.72e-2)" "unprognostic (9.55e-3)" "unprognostic (7.49e-2)" "unprognostic (3.31e-1)" "unprognostic (4.34e-2)" "unprognostic (1.03e-3)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (6.40e-2)" "unprognostic (9.16e-2)" "prognostic unfavorable (8.47e-5)" "prognostic unfavorable (8.50e-4)" "unprognostic (1.00e-1)" "unprognostic (9.25e-3)" "unprognostic (1.48e-3)" THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 40.9;Endometrial stromal cells: 67.9;Fibroblasts: 125.1;Langerhans cells: 48.4;Oligodendrocyte precursor cells: 38.2;Oligodendrocytes: 51.9;Pancreatic endocrine cells: 47.5;Smooth muscle cells: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 156.5" "Heart muscle - Fibroblasts, Lung - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA044304" Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Cell adhesion" NA NA 21000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB017716: , HPA044304: AB_2678891" "unprognostic (2.85e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (8.90e-2)" "unprognostic (3.64e-2)" "unprognostic (8.73e-2)" "unprognostic (2.93e-1)" "unprognostic (5.10e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (3.77e-6)" "unprognostic (2.19e-3)" "unprognostic (4.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.48e-3)" THBS3 ENSG00000169231 "Thrombospondin 3" P49746 1 155195588-155209051 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1072.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Rhabdoid: 98.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA006293, HPA073242" Approved Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 9400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" 3 Vesicles "HPA006293: AB_10602898, HPA073242: AB_2732223" "unprognostic (2.57e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (2.43e-4)" "prognostic unfavorable (1.44e-4)" "unprognostic (2.63e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (4.23e-1)" "unprognostic (4.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.88e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.38e-12)" "unprognostic (2.06e-2)" "unprognostic (9.41e-2)" "unprognostic (8.50e-3)" "unprognostic (2.26e-1)" THBS4 ENSG00000113296 "Thrombospondin 4" P35443 5 79991311-80083287 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Tissue remodeling, Unfolded protein response" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 209.2;heart muscle: 162.0;smooth muscle: 243.3;tongue: 206.3" "Cell type enhanced" "Detected in many" "Adipocytes: 40.7;Cone photoreceptor cells: 52.7;Early spermatids: 50.7;Fibroblasts: 71.4;Oligodendrocyte precursor cells: 56.6;Peritubular cells: 42.2;Prostatic glandular cells: 46.7;Sertoli cells: 182.2;Smooth muscle cells: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 46 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 46 "granulocytes: 4.6" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Region enriched" "Detected in many" 8 "white matter: 85.8" "Region enriched" "Detected in many" 29 "spinal cord: 117.4" "CAB004597, HPA042426" Approved Approved Vesicles "Secreted to extracellular matrix" "Growth factor" NA NA 510000000 "Cluster 22: Eosinophils - Transcription" "Cluster 7: Adipose tissue - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" Vesicles "CAB004597: AB_628352, HPA042426: AB_2677992" "unprognostic (1.41e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-3)" "unprognostic (3.64e-2)" "unprognostic (9.94e-2)" "unprognostic (8.10e-2)" "unprognostic (5.64e-2)" "unprognostic (7.12e-2)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-3)" "unprognostic (2.74e-2)" "unprognostic (3.98e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (3.33e-4)" THEM6 "C8orf55, DSCD75" ENSG00000130193 "Thioesterase superfamily member 6" Q8WUY1 8 142727223-142736927 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023255 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted - unknown location" "No annotated function" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 18: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 1 "Nuclear speckles, Cytosol" "HPA023255: AB_1845782" "unprognostic (6.20e-3)" "unprognostic (2.21e-1)" "unprognostic (9.10e-2)" "unprognostic (5.33e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-2)" "unprognostic (1.74e-2)" "unprognostic (6.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.44e-1)" "unprognostic (4.91e-2)" "unprognostic (6.76e-2)" "prognostic favorable (6.66e-7)" "unprognostic (7.02e-3)" "unprognostic (3.55e-2)" "unprognostic (2.39e-2)" "prognostic favorable (4.49e-4)" THNSL2 "FLJ10916, SOFAT, TSH2" ENSG00000144115 "Threonine synthase like 2" Q86YJ6 2 88170295-88186636 "Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.4;Proximal tubular cells: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035395 Approved "Secreted - unknown location" Cytokine NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "HPA035395: AB_10601600" "unprognostic (1.51e-2)" "unprognostic (1.03e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (4.53e-2)" "unprognostic (8.73e-2)" "unprognostic (6.64e-2)" "unprognostic (7.26e-2)" "unprognostic (1.93e-1)" "unprognostic (3.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-2)" "unprognostic (2.01e-3)" "unprognostic (6.98e-2)" "unprognostic (8.81e-2)" "unprognostic (1.40e-1)" "unprognostic (1.24e-2)" THPO "MGDF, MPLLG, TPO" ENSG00000090534 Thrombopoietin P40225 3 184371935-184381968 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 34.5" "Cell type enhanced" "Detected in some" "Early spermatids: 2.0;Excitatory neurons: 2.1;Hepatocytes: 11.9;Late spermatids: 2.9;Proximal tubular cells: 9.1" "Cancer enriched" "Detected in many" 5 "liver cancer: 8.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.1;lymphoma: 3.1" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to blood" Cytokine NA NA 1070000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "unprognostic (5.57e-2)" "unprognostic (3.15e-2)" "unprognostic (1.75e-1)" "unprognostic (2.21e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (1.37e-2)" "unprognostic (2.75e-1)" "unprognostic (1.00e-1)" "unprognostic (1.81e-1)" "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (1.40e-3)" "unprognostic (4.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.25e-2)" THSD1 TMTSP ENSG00000136114 "Thrombospondin type 1 domain containing 1" Q9NS62 13 52377167-52416373 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 18.2;Astrocytes: 24.2;Basal respiratory cells: 13.3;Endothelial cells: 23.5;Lymphatic endothelial cells: 20.6;Microglial cells: 17.0;Spermatocytes: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012611, CAB020796, HPA071106" Supported Supported Cytosol "Intracellular and membrane" "No annotated function" No No 1400000 "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Cytosol "CAB020796: , HPA012611: AB_1857990, HPA071106: " "unprognostic (1.21e-1)" "unprognostic (7.54e-3)" "unprognostic (3.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.31e-1)" "unprognostic (1.54e-2)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-1)" "unprognostic (6.10e-3)" "unprognostic (1.55e-1)" "unprognostic (3.05e-3)" "unprognostic (8.44e-2)" "unprognostic (1.31e-1)" "unprognostic (3.35e-2)" "unprognostic (4.90e-2)" THSD4 "ADAMTSL6, FLJ13710, FVSY9334, PRO34005" ENSG00000187720 "Thrombospondin type 1 domain containing 4" Q6ZMP0 15 71096952-71783383 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hydrolase "Aortic aneurysm" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 69.2;esophagus: 58.7" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 322.0;Microglial cells: 236.2;Secretory cells: 90.6;Squamous epithelial cells: 110.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 52.3" "Secreted - unknown location" Enzyme NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" "unprognostic (1.59e-1)" "unprognostic (4.38e-2)" "unprognostic (3.14e-2)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.80e-2)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-2)" "unprognostic (3.01e-3)" THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.3" "Cell type enhanced" "Detected in many" "Astrocytes: 142.7;Bipolar cells: 160.4;Horizontal cells: 97.6;Inhibitory neurons: 470.6;Microglial cells: 101.1;Oligodendrocyte precursor cells: 246.2" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 53 "basophil: 5.3" "Lineage enriched" "Detected in single" 53 "granulocytes: 5.3" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 11.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" "Developmental protein" NA NA 6100000 "Cluster 46: Basophils - Proteolysis" "Cluster 51: Thyroid gland - Unknown function" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 12 "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Adipocytes: 124.3;Endothelial cells: 103.9;Lymphatic endothelial cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.2;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.2;NK-cells: 2.5" "Group enriched" "Detected in some" 5 "Leukemia: 14.3;ovarian cancer: 18.9;Sarcoma: 23.2;thyroid cancer: 28.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA 87000000 "Cluster 15: NK-cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 7 "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" TIMD4 TIM4 ENSG00000145850 "T cell immunoglobulin and mucin domain containing 4" Q96H15 5 156919292-156963226 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 53.9;testis: 140.0" "Group enriched" "Detected in some" 36 "Early spermatids: 1158.2;Late spermatids: 1972.3" "Cancer enriched" "Detected in some" 10 "renal cancer: 6.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.5;naive CD4 T-cell: 1.6;naive CD8 T-cell: 1.6;T-reg: 4.0" "Lineage enriched" "Detected in single" 18 "T-cells: 4.0" "Group enriched" "Detected in some" 4 "Kidney cancer: 9.0;lymphoma: 4.2;Myeloma: 10.3" "Adipose subcutaneous - Macrophages, Liver - Kupffer cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015625, CAB026027" Approved Approved "Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA 32000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 4: Testis - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 11: Late spermatids - Unknown function" "Plasma membrane" "CAB026027: , HPA015625: AB_1858018" "unprognostic (2.92e-1)" "unprognostic (1.06e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (1.80e-1)" "unprognostic (3.01e-2)" "unprognostic (1.10e-1)" "unprognostic (3.11e-1)" "unprognostic (3.42e-1)" "unprognostic (8.42e-2)" "unprognostic (1.10e-1)" "unprognostic (6.90e-2)" "prognostic favorable (3.37e-4)" "unprognostic (1.31e-2)" "unprognostic (4.07e-1)" "unprognostic (3.27e-2)" "unprognostic (2.08e-2)" TIMP1 "CLGI, EPO, TIMP" ENSG00000102265 "TIMP metallopeptidase inhibitor 1" P01033 X 47582408-47586789 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 2193.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 2504.9;Langerhans cells: 2764.5;Mesothelial cells: 8111.0;monocytes: 6291.5;Pancreatic endocrine cells: 2275.3;Sertoli cells: 2317.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 427.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022360, HPA053417, CAB080273" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" "Growth factor" NA NA 127000000 520000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 29: Monocytes - Innate immune response" 3 "Golgi apparatus, Vesicles" "CAB022360: , CAB080273: , HPA053417: AB_2682142" "unprognostic (5.86e-3)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.09e-4)" "unprognostic (4.68e-2)" "unprognostic (1.81e-2)" "unprognostic (1.07e-3)" "unprognostic (4.99e-2)" "unprognostic (8.24e-3)" "unprognostic (9.12e-3)" "unprognostic (9.69e-2)" "unprognostic (9.10e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (2.90e-11)" "unprognostic (1.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (2.66e-1)" TIMP2 CSC-21K ENSG00000035862 "TIMP metallopeptidase inhibitor 2" P16035 17 78852977-78925387 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 916.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 445.7;Late spermatids: 475.8;Leydig cells: 355.4;Melanocytes: 355.6;Peritubular cells: 734.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.9" "Group enriched" "Detected in many" 4 "granulocytes: 13.9;monocytes: 5.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010203 Approved "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA 110000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 62: Connective tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "CAB010203: AB_2204966" "unprognostic (1.03e-1)" "unprognostic (1.71e-2)" "unprognostic (9.81e-2)" "unprognostic (1.76e-3)" "unprognostic (3.24e-2)" "unprognostic (3.05e-1)" "unprognostic (4.31e-1)" "unprognostic (1.63e-2)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-3)" "unprognostic (4.62e-2)" "unprognostic (2.05e-1)" "unprognostic (2.77e-3)" TIMP3 SFD ENSG00000100234 "TIMP metallopeptidase inhibitor 3" P35625 22 32801705-32863041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1559.0;Alveolar cells type 1: 1732.8;Endothelial cells: 924.7;Fibroblasts: 1235.9;Leydig cells: 1359.9;Lymphatic endothelial cells: 1097.0;Peritubular cells: 1870.2;Sertoli cells: 1112.4;Smooth muscle cells: 1255.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 604.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068391 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA 700000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 Vesicles "Golgi apparatus" "HPA068391: " "unprognostic (4.98e-2)" "unprognostic (1.77e-3)" "unprognostic (1.60e-1)" "unprognostic (8.53e-4)" "unprognostic (1.67e-2)" "unprognostic (1.05e-2)" "unprognostic (7.01e-2)" "unprognostic (3.22e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (1.90e-5)" "unprognostic (3.92e-1)" "unprognostic (1.95e-1)" "prognostic favorable (1.50e-4)" "unprognostic (2.66e-3)" "unprognostic (1.44e-2)" "unprognostic (2.55e-3)" "unprognostic (3.11e-2)" TIMP4 ENSG00000157150 "TIMP metallopeptidase inhibitor 4" Q99727 3 12153068-12158912 "Plasma proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 171.5;breast: 115.7" "Cell type enriched" "Detected in many" 6 "Adipocytes: 315.0" "Cancer enriched" "Detected in many" 13 "glioma: 66.4" "Region enhanced" "Detected in all" "cerebellum: 102.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in all" "cerebellum: 106.1" "Region enriched" "Detected in all" 9 "cerebellum: 63.5" "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "unprognostic (2.99e-2)" "unprognostic (5.14e-3)" "unprognostic (1.02e-2)" "unprognostic (2.10e-1)" "unprognostic (2.09e-2)" "unprognostic (1.97e-4)" "unprognostic (9.33e-3)" "unprognostic (4.26e-3)" "unprognostic (1.36e-1)" "unprognostic (1.74e-2)" "unprognostic (3.78e-1)" "unprognostic (6.81e-2)" "unprognostic (4.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (6.66e-5)" "unprognostic (2.86e-1)" TINAG ENSG00000137251 "Tubulointerstitial nephritis antigen" Q9UJW2 6 54307859-54390142 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 106.2" "Group enriched" "Detected in some" 5 "Distal enterocytes: 45.8;Proximal enterocytes: 70.4;Proximal tubular cells: 161.1" "Cancer enriched" "Detected in some" 4 "renal cancer: 15.8" "Region enhanced" "Detected in some" "pons: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 12.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA035427, HPA073753" Approved "Secreted to extracellular matrix" "Cell adhesion" NA NA 40000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA035427: AB_10601822, HPA073753: " "unprognostic (7.62e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.05e-5)" "unprognostic (7.27e-2)" "unprognostic (5.99e-3)" "prognostic favorable (8.75e-5)" "unprognostic (7.10e-2)" TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 315.0;Cytotrophoblasts: 1165.2;Ductal cells: 358.8;Smooth muscle cells: 371.6;Syncytiotrophoblasts: 1713.9" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 328.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Smooth muscle cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 370000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" 4 "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" TINF2 TIN2 ENSG00000092330 "TERF1 interacting nuclear factor 2" Q9BSI4 14 24238286-24242663 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 225.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059061, HPA069807" Enhanced "Nuclear bodies" "Intracellular and membrane" "No annotated function" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 19: NK-cells - Adaptive immune response" 48 "Nuclear bodies" "HPA059061: AB_2683895, HPA069807: AB_2686203" "prognostic favorable (4.96e-4)" "unprognostic (8.58e-2)" "unprognostic (1.53e-1)" "unprognostic (5.47e-2)" "unprognostic (3.20e-2)" "unprognostic (2.78e-2)" "unprognostic (4.75e-2)" "unprognostic (2.50e-1)" "unprognostic (4.70e-1)" "unprognostic (8.05e-2)" "unprognostic (1.05e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-3)" "unprognostic (2.04e-3)" "unprognostic (2.17e-1)" "unprognostic (4.78e-2)" "unprognostic (7.44e-2)" TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.2;placenta: 6.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 108.0" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 9 "cerebellum: 56.6" HPA060767 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 560000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 76: Oligodendrocyte precursor - Unknown function" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" TLL2 ENSG00000095587 "Tolloid like 2" Q9Y6L7 10 96364608-96513926 "Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.6;heart muscle: 3.5;tongue: 1.8" "Cell type enhanced" "Detected in some" "Early spermatids: 7.4;Granulosa cells: 5.2;Inhibitory neurons: 5.4;Late spermatids: 5.1;Oligodendrocytes: 17.4;Pancreatic endocrine cells: 5.1;Schwann cells: 9.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Uterine cancer: 4.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted - unknown location" "Developmental protein" NA NA "Cluster 23: Non-specific - Cellular respiration" "Cluster 49: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 26: Schwann cells & Melanocytes - Mixed function" "unprognostic (1.28e-2)" "unprognostic (7.54e-4)" "unprognostic (1.50e-1)" "unprognostic (3.31e-3)" "unprognostic (2.67e-1)" "unprognostic (2.14e-3)" "unprognostic (1.31e-2)" "unprognostic (3.52e-4)" "unprognostic (7.08e-2)" "unprognostic (2.50e-1)" "unprognostic (6.71e-2)" "unprognostic (3.37e-2)" "unprognostic (4.98e-4)" "unprognostic (2.90e-1)" "unprognostic (8.41e-2)" "unprognostic (1.95e-4)" "unprognostic (2.30e-1)" TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" Receptor "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Hofbauer cells: 72.9;Kupffer cells: 156.6;Macrophages: 80.4;monocytes: 178.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.9" "Cancer enhanced" "Detected in many" "Brain cancer: 11.7" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophil_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004025, HPA049174" Approved Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Neutrophils - Degranulation" 10 "Golgi apparatus, Plasma membrane" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" TMED4 "HNLF, p24a3, p24alpha3" ENSG00000158604 "Transmembrane p24 trafficking protein 4" Q7Z7H5 7 44577894-44582287 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014650 Approved "Intracellular and membrane" Transport NA NA 24000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 55: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "HPA014650: AB_1858066" "unprognostic (7.34e-2)" "unprognostic (1.68e-3)" "unprognostic (1.46e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.09e-3)" "unprognostic (4.50e-3)" "unprognostic (2.54e-2)" "unprognostic (3.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.61e-1)" "unprognostic (2.42e-3)" "unprognostic (4.65e-2)" "prognostic favorable (1.37e-4)" "unprognostic (1.21e-1)" "unprognostic (6.12e-2)" "unprognostic (4.11e-1)" "unprognostic (6.61e-2)" TMEFF2 "CT120.2, HPP1, TENB2, TPEF, TR" ENSG00000144339 "Transmembrane protein with EGF like and two follistatin like domains 2" Q9UIK5 2 191949043-192194933 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 25.3;prostate: 35.4;seminal vesicle: 12.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 401.3;Inhibitory neurons: 364.3;Oligodendrocyte precursor cells: 197.6;Oligodendrocytes: 1244.6;Oocytes: 161.7" "Cancer enriched" "Detected in some" 21 "prostate cancer: 57.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bone cancer: 17.2;prostate cancer: 27.6" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015587 Approved "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 5 "HPA015587: AB_1858069" "unprognostic (2.12e-3)" "unprognostic (5.37e-1)" "unprognostic (3.10e-1)" "unprognostic (5.89e-7)" "unprognostic (4.96e-2)" "unprognostic (1.27e-1)" "unprognostic (8.82e-2)" "unprognostic (1.64e-1)" "unprognostic (1.86e-1)" "unprognostic (5.55e-2)" "unprognostic (2.09e-2)" "unprognostic (3.79e-2)" "unprognostic (4.17e-3)" "unprognostic (1.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.20e-1)" TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 33.8;skeletal muscle: 22.3" "Group enriched" "Detected in many" 4 "Astrocytes: 199.1;Excitatory neurons: 345.5;Inhibitory neurons: 456.7;Oligodendrocyte precursor cells: 450.4" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "Neuroblastoma: 56.7" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Enhanced Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 55000 "Cluster 3: Non-specific - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" 3 "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: AB_2684993" "unprognostic (4.75e-2)" "unprognostic (1.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.07e-3)" "unprognostic (3.17e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-2)" "unprognostic (2.06e-4)" "unprognostic (2.08e-1)" "unprognostic (7.27e-4)" "unprognostic (1.11e-1)" "unprognostic (3.03e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-2)" "unprognostic (6.12e-2)" "unprognostic (1.36e-2)" TMEM25 FLJ14399 ENSG00000149582 "Transmembrane protein 25" Q86YD3 11 118531041-118547280 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 76.5;Proximal enterocytes: 138.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012163, HPA051562" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 6900000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "Golgi apparatus, Vesicles" "HPA012163: AB_1858112, HPA051562: AB_2681535" "unprognostic (1.53e-2)" "unprognostic (7.18e-2)" "unprognostic (2.43e-1)" "unprognostic (6.69e-2)" "unprognostic (3.61e-1)" "unprognostic (6.50e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-3)" "unprognostic (1.58e-1)" "unprognostic (3.42e-1)" "unprognostic (1.66e-2)" "unprognostic (8.19e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.15e-1)" "unprognostic (2.51e-1)" "unprognostic (1.26e-1)" "unprognostic (7.01e-2)" TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 28.2;Endothelial cells: 24.2;granulocytes: 74.2;Intestinal goblet cells: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 3.6;NK-cell: 8.3" "Group enriched" "Detected in many" 9 "granulocytes: 3.6;NK-cells: 8.3" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043718 Uncertain Approved Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 30: Granulocytes - Unknown function" Cytosol "HPA043718: AB_10794662" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (8.31e-3)" "unprognostic (4.53e-2)" "unprognostic (2.78e-3)" "unprognostic (9.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.70e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (6.55e-13)" "unprognostic (1.23e-2)" "unprognostic (3.36e-1)" "unprognostic (1.65e-3)" "unprognostic (5.66e-2)" TMEM52 ENSG00000178821 "Transmembrane protein 52" Q8NDY8 1 1917590-1919279 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 209.9;skeletal muscle: 288.4;tongue: 199.5" "Cell type enriched" "Detected in many" 5 "Skeletal myocytes: 227.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA079372 Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 2: Skeletal myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "HPA079372: " "unprognostic (4.39e-2)" "unprognostic (2.60e-1)" "unprognostic (3.76e-2)" "unprognostic (7.35e-3)" "unprognostic (1.04e-5)" "unprognostic (1.46e-1)" "unprognostic (6.71e-3)" "unprognostic (3.68e-2)" "unprognostic (9.49e-2)" "unprognostic (1.69e-1)" "unprognostic (3.83e-3)" "unprognostic (5.80e-2)" "unprognostic (8.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-2)" TMEM87A DKFZP564G2022 ENSG00000103978 "Transmembrane protein 87A" Q8NBN3 15 42210447-42273534 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018104, HPA018189" Enhanced Supported "Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 72: Alveolar cells - Lung function" "Golgi apparatus" "HPA018104: AB_1858135, HPA018189: AB_2205198" "unprognostic (7.07e-2)" "unprognostic (1.62e-2)" "unprognostic (2.19e-1)" "unprognostic (4.05e-2)" "unprognostic (2.49e-1)" "unprognostic (6.39e-3)" "unprognostic (1.19e-2)" "unprognostic (2.44e-1)" "unprognostic (2.95e-1)" "unprognostic (8.13e-3)" "unprognostic (4.31e-3)" "unprognostic (1.38e-1)" "unprognostic (3.41e-2)" "unprognostic (7.90e-2)" "unprognostic (2.19e-1)" "unprognostic (5.49e-3)" "unprognostic (3.63e-1)" TMEM95 "MGC129793, UNQ9390" ENSG00000182896 "Transmembrane protein 95" Q3KNT9 17 7355123-7357219 "Predicted intracellular proteins, Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 108 "testis: 10.8" "Cell type enhanced" "Detected in some" "Early spermatids: 55.6;Late spermatids: 36.1;Schwann cells: 12.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Intracellular and membrane" Other NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 18: Early spermatids - Unknown function" 3 "unprognostic (1.54e-1)" "unprognostic (1.03e-1)" "unprognostic (1.15e-1)" "unprognostic (5.15e-2)" "unprognostic (7.42e-2)" "unprognostic (7.44e-2)" TMEM98 DKFZP564K1964 ENSG00000006042 "Transmembrane protein 98" Q9Y2Y6 17 32927910-32945106 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 404.0" "Cell type enhanced" "Detected in many" "Mesothelial cells: 197.7;Ovarian stromal cells: 241.9;Proximal enterocytes: 249.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 4.0" "Lineage enriched" "Detected in single" 12 "dendritic cells: 4.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040473, HPA053385" Uncertain Supported Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 6 Nucleoplasm "HPA040473: AB_10794876, HPA053385: AB_2682134" "unprognostic (1.55e-2)" "unprognostic (5.15e-2)" "unprognostic (4.36e-3)" "unprognostic (7.20e-2)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.14e-4)" "prognostic favorable (7.10e-4)" "unprognostic (6.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.41e-1)" "unprognostic (9.18e-3)" "prognostic favorable (3.85e-4)" "unprognostic (5.16e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-1)" TMPRSS11D "ASP, HAT" ENSG00000153802 "Transmembrane serine protease 11D" O60235 4 67820876-67884002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 84 "cervix: 50.1;esophagus: 69.8;lymphoid tissue: 33.5;salivary gland: 20.4;vagina: 73.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 58.9;Basal respiratory cells: 23.9;Serous glandular cells: 48.6;Suprabasal keratinocytes: 124.2" "Group enriched" "Detected in many" 5 "cervical cancer: 36.0;head and neck cancer: 30.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 2.1;head and neck cancer: 1.6;lymphoma: 2.4" "Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA077704 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "HPA077704: " "unprognostic (1.19e-1)" "unprognostic (6.83e-2)" "unprognostic (8.82e-2)" "unprognostic (2.10e-2)" "unprognostic (1.21e-2)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (4.79e-1)" "unprognostic (4.38e-3)" "unprognostic (1.96e-1)" "unprognostic (6.91e-2)" "unprognostic (4.48e-2)" "unprognostic (2.19e-3)" TMPRSS11E "DESC1, TMPRSS11E2" ENSG00000087128 "Transmembrane serine protease 11E" Q9UL52 4 68447463-68497604 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 87.1;esophagus: 214.0;salivary gland: 55.0;vagina: 151.5" "Group enriched" "Detected in some" 6 "Ionocytes: 73.3;Salivary duct cells: 82.9;Suprabasal keratinocytes: 67.4" "Group enriched" "Detected in many" 6 "cervical cancer: 22.0;head and neck cancer: 25.3;lung cancer: 11.5;urothelial cancer: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 8.2" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043816, HPA051062" Enhanced Approved "Golgi apparatus" "Secreted in other tissues" Enzyme NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Golgi apparatus" "HPA043816: , HPA051062: AB_2681329" "unprognostic (2.53e-1)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" "unprognostic (9.14e-2)" "unprognostic (5.03e-2)" "prognostic unfavorable (6.73e-4)" "unprognostic (2.22e-1)" "unprognostic (9.70e-3)" "unprognostic (2.16e-1)" "unprognostic (3.74e-2)" "unprognostic (4.03e-2)" "unprognostic (8.39e-2)" "unprognostic (1.27e-1)" "unprognostic (3.08e-3)" TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 271.1;stomach 1: 142.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 264.9;Gastric mucus-secreting cells: 171.0;Paneth cells: 147.3;Prostatic glandular cells: 371.1;Proximal enterocytes: 168.4" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 267.6" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 2 "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" TMPRSS4 "CAP2, MT-SP2, TMPRSS3" ENSG00000137648 "Transmembrane serine protease 4" Q9NRS4 11 118077012-118121890 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 105.7;intestine: 42.1;urinary bladder: 71.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 99.4;Basal squamous epithelial cells: 61.8;Club cells: 111.2;Distal enterocytes: 143.5;Glandular and luminal cells: 64.6;Ionocytes: 135.5;Squamous epithelial cells: 126.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 2.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 70.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006238 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 10 "HPA006238: AB_1080316" "unprognostic (1.48e-1)" "unprognostic (3.27e-2)" "unprognostic (1.19e-2)" "unprognostic (1.23e-1)" "unprognostic (5.23e-2)" "unprognostic (5.50e-2)" "unprognostic (8.17e-3)" "unprognostic (1.95e-2)" "unprognostic (2.41e-1)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-2)" "unprognostic (9.96e-3)" TMX2 "PDIA12, TXNDC14" ENSG00000213593 "Thioredoxin related transmembrane protein 2" Q9Y320 11 57712593-57740973 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Intellectual disability, Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040282, HPA063763" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 131 "Nucleoplasm, Cytosol" "HPA040282: AB_10697715, HPA063763: AB_2685116" "unprognostic (3.66e-3)" "unprognostic (6.96e-2)" "unprognostic (6.69e-3)" "unprognostic (2.73e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.64e-4)" "prognostic unfavorable (4.11e-4)" "unprognostic (4.48e-2)" "unprognostic (2.98e-1)" "unprognostic (7.26e-3)" "unprognostic (1.90e-2)" "unprognostic (2.22e-1)" "prognostic favorable (1.55e-5)" "unprognostic (5.88e-3)" "unprognostic (4.19e-2)" "unprognostic (3.40e-1)" "prognostic unfavorable (3.37e-4)" TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" Enzyme NA NA 36000 "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" TNC "DFNA56, HXB, MGC167029, TN" ENSG00000041982 "Tenascin C" P24821 9 115019575-115118207 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 215.1;smooth muscle: 461.1" "Cell type enhanced" "Detected in many" "Astrocytes: 152.0;Basal respiratory cells: 141.7;Basal squamous epithelial cells: 57.0;Endometrial stromal cells: 44.1;Fibroblasts: 62.3;Smooth muscle cells: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 378.1" "Colon - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004592, HPA004823" Approved "Secreted to extracellular matrix" "Cell adhesion" NA NA 560000000 840000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 "CAB004592: AB_628342, HPA004823: AB_1080243" "unprognostic (5.46e-2)" "unprognostic (3.76e-2)" "unprognostic (7.57e-2)" "unprognostic (1.69e-1)" "unprognostic (9.20e-2)" "unprognostic (1.39e-1)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (7.86e-3)" "unprognostic (2.68e-3)" "unprognostic (1.59e-2)" "unprognostic (1.82e-1)" "unprognostic (4.87e-3)" "unprognostic (1.79e-2)" "unprognostic (1.92e-2)" "unprognostic (7.60e-2)" "unprognostic (1.97e-3)" TNF "DIF, TNF-alpha, TNFA, TNFSF2" ENSG00000232810 "Tumor necrosis factor" P01375 6 31575565-31578336 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.9;lymphoid tissue: 6.3" "Cell type enhanced" "Detected in many" "B-cells: 100.4;Hofbauer cells: 84.3;Langerhans cells: 59.4;Macrophages: 158.2;monocytes: 97.8;Secretory cells: 58.0;T-cells: 93.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 73.4" "Group enriched" "Detected in all" 6 "granulocytes: 22.7;monocytes: 73.4;T-cells: 41.4" "Group enriched" "Detected in many" 5 "Leukemia: 13.7;lymphoma: 34.9" "Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" CAB078469 Supported "Secreted to blood" Cytokine NA NA 10100 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 80: Non-specific - Transcription" 32 "CAB078469: AB_908070" "unprognostic (1.93e-1)" "unprognostic (1.07e-2)" "unprognostic (3.85e-2)" "unprognostic (1.05e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-2)" "unprognostic (1.67e-1)" "unprognostic (3.46e-1)" "unprognostic (1.19e-2)" "unprognostic (1.94e-1)" "unprognostic (3.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-2)" "unprognostic (1.82e-1)" "unprognostic (9.85e-3)" "unprognostic (1.09e-1)" "unprognostic (2.04e-1)" TNFAIP6 "TSG-6, TSG6" ENSG00000123610 "TNF alpha induced protein 6" P98066 2 151357592-151380046 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "urinary bladder: 188.8" "Cell type enhanced" "Detected in many" "Early spermatids: 500.1;Fibroblasts: 213.8;Langerhans cells: 93.6;Late spermatids: 100.0;monocytes: 318.3;Schwann cells: 88.2" "Cancer enhanced" "Detected in many" "renal cancer: 27.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 22 "neutrophil: 183.6" "Lineage enriched" "Detected in many" 22 "granulocytes: 183.6" "Group enriched" "Detected in many" 6 "Bone cancer: 22.6;Kidney cancer: 58.1" "Heart muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB032719, HPA050884" Uncertain "Secreted to blood" "Cell adhesion" NA NA 100000 "Cluster 4: Neutrophils - Degranulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 5 "CAB032719: AB_2204650, HPA050884: AB_2681261" "unprognostic (1.31e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (8.66e-2)" "unprognostic (2.51e-2)" "unprognostic (1.15e-3)" "unprognostic (3.26e-3)" "unprognostic (3.75e-4)" "unprognostic (4.49e-3)" "unprognostic (1.22e-1)" "unprognostic (1.90e-1)" "unprognostic (5.87e-3)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.59e-4)" "unprognostic (1.06e-2)" "unprognostic (1.25e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (9.16e-5)" TNFRSF11A "CD265, FEO, LOH18CR1, ODFR, PDB2, RANK, TRANCE-R" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.4;salivary gland: 24.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 32.3;Enteroendocrine cells: 21.9;Lymphatic endothelial cells: 27.9;Paneth cells: 39.1;Proximal enterocytes: 23.4;Serous glandular cells: 36.3;Undifferentiated cells: 33.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 2.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 2.3" "Cancer enhanced" "Detected in many" "Gastric cancer: 9.7" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Skeletal muscle - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 110000 "Cluster 15: NK-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 50: Lymphoma - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" TNFRSF11B "OCIF, OPG, TR1" ENSG00000164761 "TNF receptor superfamily member 11b" O00300 8 118923557-118951885 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 28.8;thyroid gland: 98.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 129.2;Collecting duct cells: 64.2;Mesothelial cells: 80.4;Pancreatic endocrine cells: 32.3;Proximal tubular cells: 106.7" "Cancer enhanced" "Detected in all" "renal cancer: 22.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 40 "plasmacytoid DC: 4.0" "Lineage enriched" "Detected in single" 40 "dendritic cells: 4.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 54.6" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034939, HPA058613" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted in other tissues" Receptor NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 51: Thyroid gland - Unknown function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 17: Breast glandular cells - Lactation" 3 "Golgi apparatus" "Nucleoplasm, Nucleoli" "CAB034939: , HPA058613: " "unprognostic (1.39e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (5.27e-2)" "unprognostic (2.33e-2)" "unprognostic (4.27e-3)" "unprognostic (1.10e-3)" "unprognostic (1.21e-3)" "unprognostic (5.50e-2)" "unprognostic (9.94e-2)" "unprognostic (6.32e-2)" "unprognostic (3.53e-2)" "unprognostic (2.43e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.32e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (3.88e-4)" TNFRSF18 "AITR, CD357, GITR" ENSG00000186891 "TNF receptor superfamily member 18" Q9Y5U5 1 1203508-1206592 "CD markers, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 37.5" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 104.9;granulocytes: 35.5;Langerhans cells: 77.5;NK-cells: 77.0;Plasma cells: 92.5;Suprabasal keratinocytes: 76.6;T-cells: 73.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "NK-cell: 184.9;T-reg: 72.0" "Group enriched" "Detected in many" 11 "NK-cells: 184.9;T-cells: 72.0" "Cancer enhanced" "Detected in many" "lymphoma: 36.8;Myeloma: 25.5" "Skin - Keratinocyte (other), Stomach - Plasma cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 8 "basal ganglia: 1.2" HPA008025 Approved "Secreted to blood" Receptor NA NA "Cluster 1: T-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "HPA008025: AB_1849696" "unprognostic (1.20e-3)" "unprognostic (4.61e-2)" "unprognostic (4.59e-2)" "prognostic favorable (7.72e-6)" "unprognostic (2.73e-4)" "prognostic favorable (4.12e-4)" "unprognostic (3.43e-2)" "unprognostic (2.31e-1)" "unprognostic (3.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.00e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (4.40e-11)" "unprognostic (1.02e-3)" "unprognostic (2.39e-1)" "unprognostic (3.74e-1)" "unprognostic (2.08e-1)" TNFRSF1A "CD120a, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR60" ENSG00000067182 "TNF receptor superfamily member 1A" P19438 12 6328757-6342114 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Host-virus interaction" Receptor "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 454.7" "Group enriched" "Detected in many" 4 "dendritic cells: 116.0;granulocytes: 454.7;monocytes: 152.3" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004102, CAB010309" Approved "Secreted to blood" Receptor NA NA 17700 570000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 7 "CAB010309: AB_2206639, HPA004102: AB_1846232" "unprognostic (2.19e-2)" "unprognostic (3.76e-2)" "unprognostic (8.14e-2)" "prognostic favorable (8.22e-4)" "unprognostic (3.07e-2)" "prognostic unfavorable (3.68e-4)" "unprognostic (1.50e-1)" "unprognostic (1.41e-3)" "unprognostic (1.00e-1)" "unprognostic (8.05e-2)" "unprognostic (4.78e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (5.14e-3)" "unprognostic (1.74e-1)" TNFRSF1B "CD120b, p75, TNF-R-II, TNF-R75, TNFBR, TNFR2, TNFR80" ENSG00000028137 "TNF receptor superfamily member 1B" P20333 1 12166991-12209228 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 66.5" "Cell type enhanced" "Detected in many" "dendritic cells: 328.8;Kupffer cells: 240.4;Langerhans cells: 352.6;Macrophages: 265.8;monocytes: 743.2;NK-cells: 332.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 387.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 29.3" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA004796 Approved "Secreted to blood" Receptor NA NA 3230000 8100000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" 3 "HPA004796: AB_1078436" "unprognostic (4.45e-2)" "unprognostic (2.27e-3)" "unprognostic (7.62e-2)" "unprognostic (3.82e-3)" "unprognostic (6.30e-2)" "unprognostic (4.47e-3)" "unprognostic (5.28e-3)" "unprognostic (2.79e-1)" "unprognostic (1.69e-2)" "unprognostic (1.73e-2)" "unprognostic (7.26e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.35e-5)" "unprognostic (2.02e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.26e-2)" "unprognostic (1.10e-1)" TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.2;lymphoid tissue: 42.9;pituitary gland: 29.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 30.7;Excitatory neurons: 36.3;T-cells: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Low cancer specificity" "Detected in many" "Breast - T-cells, Skeletal muscle - Fibroblasts" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Low region specificity" "Detected in many" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" Receptor NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 24: Non-specific - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" TNFRSF6B "DcR3, M68, TR6" ENSG00000243509 "TNF receptor superfamily member 6b" O95407 20 63696652-63698684 "Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 21.6" "Lineage enriched" "Detected in many" 16 "dendritic cells: 21.6" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 144.8;pancreatic cancer: 170.2" HPA047154 Approved "Secreted to blood" Receptor NA NA 406000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" 2 "HPA047154: AB_2679959" TNFSF10 "Apo-2L, CD253, TL2, TRAIL" ENSG00000121858 "TNF superfamily member 10" P50591 3 172505508-172523475 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Apoptosis Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 385.4;Ductal cells: 709.4;Proximal tubular cells: 567.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 266.3;classical monocyte: 133.5;intermediate monocyte: 203.5;neutrophil: 257.9;non-classical monocyte: 214.1" "Group enriched" "Detected in all" 5 "granulocytes: 266.3;monocytes: 214.1" "Group enriched" "Detected in many" 4 "head and neck cancer: 121.7;Kidney cancer: 166.1" "Liver - Hepatocytes" "Low region specificity" "Detected in all" HPA054938 Uncertain "Secreted to blood" Cytokine NA NA 67400 18000 "Cluster 28: Neutrophils - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 2 "HPA054938: AB_2682643" "unprognostic (9.16e-2)" "unprognostic (2.79e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-3)" "unprognostic (2.52e-1)" "unprognostic (2.67e-1)" "unprognostic (1.55e-1)" "unprognostic (2.01e-1)" "unprognostic (1.99e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (9.43e-4)" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (3.68e-2)" "unprognostic (1.32e-1)" "unprognostic (6.27e-2)" TNFSF11 "CD254, ODF, OPGL, RANKL, TRANCE" ENSG00000120659 "TNF superfamily member 11" O14788 13 42562736-42608013 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Cytokine, Developmental protein, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 4.0;lymphoid tissue: 12.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 10.1;Ductal cells: 5.6;Early spermatids: 8.4;Late spermatids: 14.2;NK-cells: 3.9;Pancreatic endocrine cells: 3.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 2.6" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 8 "NK-cell: 9.9" "Lineage enriched" "Detected in many" 8 "NK-cells: 9.9" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.5;thyroid cancer: 1.7" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009193, HPA045142" Enhanced "Secreted to blood" Cytokine NA NA 17200 "Cluster 15: NK-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 17: Breast glandular cells - Lactation" 4 "CAB009193: , HPA045142: AB_2679231" "unprognostic (3.97e-4)" "unprognostic (1.40e-1)" "unprognostic (9.01e-3)" "unprognostic (3.81e-3)" "unprognostic (1.12e-1)" "unprognostic (1.09e-1)" "unprognostic (7.09e-2)" "unprognostic (7.70e-2)" "unprognostic (2.29e-1)" "unprognostic (1.25e-3)" "unprognostic (1.00e-1)" "unprognostic (1.50e-1)" "unprognostic (3.94e-5)" "unprognostic (1.87e-1)" "unprognostic (9.67e-2)" "unprognostic (5.46e-2)" "unprognostic (7.74e-2)" TNFSF12 "APO3L, DR3LG, TWEAK" ENSG00000239697 "TNF superfamily member 12" O43508 17 7548508-7557890 "Predicted secreted proteins" "Angiogenesis, Apoptosis, Differentiation" "Cytokine, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 102.1;granulocytes: 89.4;Smooth muscle cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035984, HPA052967" Uncertain Approved Vesicles "Secreted to blood" Cytokine NA NA 853000 130000 "Cluster 33: Non-specific - ATP binding" "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 6 Vesicles "HPA035984: , HPA052967: AB_2682000" "unprognostic (2.96e-3)" "unprognostic (2.96e-1)" "unprognostic (4.71e-2)" "prognostic favorable (5.70e-5)" "unprognostic (5.31e-2)" "unprognostic (7.91e-2)" "unprognostic (6.45e-2)" "unprognostic (2.38e-2)" "unprognostic (4.48e-2)" "unprognostic (6.09e-2)" "unprognostic (6.20e-2)" "unprognostic (8.62e-2)" "unprognostic (3.29e-2)" "unprognostic (4.11e-2)" "unprognostic (3.15e-2)" "unprognostic (8.74e-2)" "unprognostic (2.38e-1)" TNFSF12-TNFSF13 TWE-PRIL ENSG00000248871 "TNFSF12-TNFSF13 readthrough" 17 7549099-7561601 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 7.1" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA004863, HPA035984, HPA052967" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 58: Macrophages - Innate immune response" Vesicles "HPA004863: AB_1078187, HPA035984: , HPA052967: AB_2682000" "unprognostic (1.59e-1)" "unprognostic (1.48e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (3.04e-1)" "unprognostic (2.19e-1)" "unprognostic (1.05e-2)" "unprognostic (1.40e-1)" "unprognostic (8.96e-3)" "unprognostic (1.38e-2)" "unprognostic (2.05e-1)" "unprognostic (8.23e-2)" TNFSF13 "APRIL, CD256" ENSG00000161955 "TNF superfamily member 13" O75888 17 7558292-7561608 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 174.6;salivary gland: 143.4" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 4.7;Erythroid cells: 4.5;Gastric mucus-secreting cells: 10.6;Macrophages: 11.2;Mesothelial cells: 13.2;Schwann cells: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 384.4" "Group enriched" "Detected in all" 11 "dendritic cells: 249.2;granulocytes: 139.3;monocytes: 384.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004863 Uncertain "Secreted to blood" Cytokine NA NA 6770000 35000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Non-specific - Transcription" "HPA004863: AB_1078187" "unprognostic (2.46e-2)" "unprognostic (2.20e-1)" "unprognostic (3.42e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (9.73e-4)" "unprognostic (3.57e-1)" "unprognostic (3.32e-2)" "unprognostic (3.70e-2)" "unprognostic (3.75e-1)" "unprognostic (1.15e-1)" "unprognostic (6.95e-2)" "unprognostic (2.65e-1)" "prognostic favorable (1.30e-9)" "unprognostic (4.69e-2)" "unprognostic (1.42e-2)" "unprognostic (3.46e-1)" "unprognostic (3.38e-2)" TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.8;lymphoid tissue: 25.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 167.6;Kupffer cells: 106.6;Langerhans cells: 300.8;Macrophages: 143.4;monocytes: 542.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 509.3" "Group enriched" "Detected in all" 11 "dendritic cells: 207.0;granulocytes: 509.3;monocytes: 352.4" "Cancer enriched" "Detected in some" 10 "Leukemia: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" Cytokine NA NA 393000 790000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 3 "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" TNFSF14 "CD258, HVEM-L, LIGHT, LTg" ENSG00000125735 "TNF superfamily member 14" O43557 19 6661253-6670588 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 28.0;liver: 105.3" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 22.2;Mesothelial cells: 45.1;NK-cells: 44.3;T-cells: 56.1" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 199.9" "Group enriched" "Detected in all" 4 "granulocytes: 199.9;T-cells: 61.2" "Cancer enhanced" "Detected in some" "Leukemia: 2.6;lymphoma: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA012700 Uncertain Approved Vesicles "Secreted to blood" Cytokine NA NA 41000 "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 19: NK-cells - Adaptive immune response" 19 Vesicles "HPA012700: AB_1852870" "unprognostic (2.78e-3)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (2.35e-3)" "unprognostic (3.82e-4)" "unprognostic (4.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (1.05e-2)" "unprognostic (9.23e-2)" "unprognostic (9.22e-2)" "unprognostic (3.59e-1)" "prognostic unfavorable (6.07e-13)" "unprognostic (1.09e-1)" "unprognostic (9.56e-3)" "unprognostic (1.75e-1)" "unprognostic (3.62e-2)" TNFSF15 "MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A" ENSG00000181634 "TNF superfamily member 15" O95150 9 114784652-114806039 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 20.2;Basal respiratory cells: 25.4;Basal squamous epithelial cells: 15.7;Club cells: 19.8;Glandular and luminal cells: 33.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012948, HPA046522" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" "Secreted to blood" Cytokine NA NA 1110000 "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 37: Glandular & Luminal cells - Unknown function" 2 "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA012948: AB_1858024, HPA046522: AB_2679683" "unprognostic (3.41e-1)" "unprognostic (2.06e-2)" "unprognostic (3.76e-1)" "unprognostic (1.52e-2)" "unprognostic (3.26e-2)" "unprognostic (1.67e-2)" "unprognostic (1.64e-1)" "unprognostic (2.29e-2)" "unprognostic (5.40e-2)" "unprognostic (1.38e-1)" "unprognostic (7.78e-2)" "unprognostic (2.09e-1)" "unprognostic (8.64e-5)" "unprognostic (1.97e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-3)" "unprognostic (4.46e-3)" TNN TNW ENSG00000120332 "Tenascin N" Q9UQP3 1 175067833-175148075 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 11.6;breast: 4.7" "Group enriched" "Detected in some" 4 "Adipocytes: 4.6;Fibroblasts: 6.1;Smooth muscle cells: 12.3" "Cancer enhanced" "Detected in some" "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.2;Leukemia: 1.3;Myeloma: 1.6" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010907, HPA026726, HPA026764" Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 34000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" "CAB010907: AB_477565, HPA026726: AB_10601771, HPA026764: AB_10601859" "unprognostic (1.16e-3)" "unprognostic (2.23e-2)" "unprognostic (1.35e-1)" "unprognostic (2.21e-2)" "unprognostic (1.34e-1)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (3.55e-1)" "unprognostic (5.25e-3)" "unprognostic (1.01e-2)" "unprognostic (4.69e-1)" "unprognostic (5.07e-1)" "unprognostic (1.08e-3)" "unprognostic (1.76e-2)" "unprognostic (9.38e-3)" "unprognostic (1.89e-2)" "unprognostic (1.02e-2)" TNR ENSG00000116147 "Tenascin R" Q92752 1 175315194-175743616 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 40.3;retina: 15.8" "Cell type enriched" "Detected in some" 9 "Oligodendrocyte precursor cells: 2147.5" "Cancer enriched" "Detected in single" 46 "glioma: 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.1;thyroid cancer: 3.7" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022343, HPA027134, HPA027150, HPA029859" Enhanced "Secreted in brain" "Cell adhesion" NA NA 58000 "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" "CAB022343: , HPA027134: AB_1851983, HPA027150: AB_1851985, HPA029859: AB_10600916" "unprognostic (1.04e-1)" "unprognostic (7.43e-2)" "unprognostic (3.11e-2)" "unprognostic (1.12e-3)" "unprognostic (2.38e-1)" "unprognostic (1.51e-2)" "unprognostic (9.66e-2)" "unprognostic (2.57e-2)" "unprognostic (5.79e-2)" "unprognostic (5.06e-2)" "unprognostic (3.03e-3)" "unprognostic (7.26e-4)" "unprognostic (4.48e-4)" "unprognostic (3.26e-3)" "unprognostic (3.83e-1)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" TNXB "HXBL, TN-X, TNX, TNXB1, TNXB2, TNXBS, XB, XBS" ENSG00000168477 "Tenascin XB" P22105 6 32041153-32115334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 266.2" "Group enriched" "Detected in many" 4 "Fibroblasts: 217.7;Lymphatic endothelial cells: 245.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_1, Skeletal muscle - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA016017, HPA070464" Supported Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 1500000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 Vesicles "HPA016017: , HPA070464: AB_2686269" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.62e-3)" "unprognostic (9.57e-2)" "unprognostic (1.16e-1)" "unprognostic (9.51e-4)" "unprognostic (5.71e-2)" "unprognostic (2.30e-1)" "unprognostic (6.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.61e-2)" "unprognostic (2.17e-1)" "unprognostic (9.70e-2)" "unprognostic (3.13e-2)" "unprognostic (2.02e-1)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" TOGARAM1 "crescerin, Crescerin-1, FAM179B, KIAA0423" ENSG00000198718 "TOG array regulator of axonemal microtubules 1" Q9Y4F4 14 44962190-45074431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 100.2;Oligodendrocytes: 143.4;Rod photoreceptor cells: 119.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 4.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.8" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053559 Uncertain "Intracellular and membrane" Other NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 66: Photoreceptor cells - Visual perception" "HPA053559: AB_2682190" "unprognostic (2.91e-1)" "unprognostic (4.07e-2)" "unprognostic (2.04e-2)" "unprognostic (1.05e-2)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (4.88e-2)" "unprognostic (2.67e-2)" "unprognostic (2.69e-1)" "unprognostic (1.21e-1)" "unprognostic (5.63e-2)" "unprognostic (6.49e-2)" "prognostic favorable (8.38e-4)" "unprognostic (1.62e-1)" "unprognostic (2.15e-1)" "unprognostic (3.02e-2)" "unprognostic (1.60e-1)" TOR1A "DQ2, DYT1" ENSG00000136827 "Torsin family 1 member A" O14656 9 129812942-129824244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012473, HPA051195" Approved Supported "Nuclear membrane,Vesicles" "Intracellular and membrane" Enzyme NA NA 20000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 8 "Nuclear membrane, Vesicles" "CAB012473: AB_2240792, HPA051195: AB_2681382" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.95e-1)" "unprognostic (1.86e-3)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.10e-2)" "unprognostic (1.41e-1)" "unprognostic (4.10e-2)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (3.39e-1)" "unprognostic (1.91e-1)" "unprognostic (1.77e-1)" "unprognostic (1.99e-1)" TOR1B "DQ1, MGC4386" ENSG00000136816 "Torsin family 1 member B" O14657 9 129803157-129811281 "Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013403, HPA013697, CAB022709" Approved Uncertain "Nuclear speckles,Cytosol" "Intracellular and membrane" Enzyme NA NA 140000 "Cluster 28: Neutrophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Mixed function" "Nuclear speckles" Cytosol "CAB022709: , HPA013403: AB_1858195, HPA013697: AB_1858196" "unprognostic (2.91e-3)" "unprognostic (1.73e-1)" "unprognostic (1.14e-1)" "unprognostic (8.55e-2)" "unprognostic (3.23e-1)" "unprognostic (3.72e-2)" "unprognostic (1.75e-1)" "unprognostic (5.73e-3)" "unprognostic (1.95e-1)" "unprognostic (7.47e-2)" "unprognostic (1.40e-1)" "unprognostic (2.13e-2)" "unprognostic (2.07e-3)" "unprognostic (4.09e-2)" "unprognostic (1.23e-1)" "unprognostic (5.40e-3)" "unprognostic (1.69e-3)" TOR2A "FLJ14771, TORP1" ENSG00000160404 "Torsin family 2 member A" "Q5JU69, Q8N2E6" 9 127731524-127735313 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 86.4;Hofbauer cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071229 Approved Uncertain "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" Hormone NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 29: Monocytes - Innate immune response" "Endoplasmic reticulum, Plasma membrane" "HPA071229: AB_2732175" "unprognostic (1.67e-1)" "unprognostic (9.19e-3)" "unprognostic (1.47e-1)" "unprognostic (1.27e-3)" "unprognostic (3.04e-2)" "unprognostic (6.97e-2)" "unprognostic (2.43e-3)" "unprognostic (4.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.33e-1)" "unprognostic (6.51e-3)" "unprognostic (1.05e-2)" "unprognostic (6.98e-2)" "prognostic favorable (7.51e-4)" "unprognostic (1.72e-1)" "unprognostic (3.27e-1)" "unprognostic (2.82e-2)" TOR3A "ADIR, ADIR2, FLJ22345" ENSG00000186283 "Torsin family 3 member A" Q9H497 1 179082070-179098023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 143.1;Oocytes: 105.1;Plasma cells: 171.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028766 Approved "Intracellular and membrane" "No annotated function" NA Yes 24000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 20: Myeloma - Immune response" "Cluster 77: Plasma cells - Protein processing" "HPA028766: AB_10602251" "unprognostic (5.55e-2)" "unprognostic (6.52e-2)" "unprognostic (2.80e-1)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (3.90e-1)" "unprognostic (8.82e-3)" "unprognostic (6.47e-2)" "unprognostic (2.02e-2)" "unprognostic (4.87e-2)" "unprognostic (2.27e-1)" "unprognostic (3.99e-1)" "prognostic unfavorable (4.78e-8)" "unprognostic (4.26e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-1)" "unprognostic (1.35e-1)" TPO TPX ENSG00000115705 "Thyroid peroxidase" P07202 2 1374066-1543711 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 69 "thyroid gland: 1540.7" "Cell type enhanced" "Detected in some" "Adipocytes: 24.9;Endothelial cells: 14.3;Late spermatids: 7.3;Oocytes: 44.8" "Cancer enriched" "Detected in some" 364 "thyroid cancer: 188.3" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 12 "memory CD4 T-cell: 2.0;T-reg: 1.2" "Lineage enriched" "Detected in single" 20 "T-cells: 2.0" "Group enriched" "Detected in some" 6 "Myeloma: 4.7;thyroid cancer: 6.1" "Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007987, CAB009587, HPA073226" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 51: Thyroid gland - Unknown function" "Cluster 53: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "CAB009587: , HPA007987: AB_1080270, HPA073226: " "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" "unprognostic (2.88e-1)" "unprognostic (1.77e-2)" "unprognostic (3.56e-2)" "unprognostic (9.11e-2)" "unprognostic (2.24e-2)" "unprognostic (1.85e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-4)" "unprognostic (2.61e-2)" "unprognostic (3.29e-1)" "unprognostic (5.44e-4)" "unprognostic (1.21e-1)" "unprognostic (3.73e-2)" "unprognostic (4.98e-3)" "unprognostic (7.10e-3)" TPP1 "CLN2, LPIC, SCAR7, TPP-1" ENSG00000166340 "Tripeptidyl peptidase 1" O14773 11 6612768-6619448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Neuronal ceroid lipofuscinosis, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 273.8;Kupffer cells: 364.8;Macrophages: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037709, HPA044868" Enhanced "Intracellular and membrane" Enzyme NA NA 9500000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" 9 "HPA037709: AB_10672913, HPA044868: AB_2679122" "unprognostic (8.27e-3)" "unprognostic (5.85e-2)" "unprognostic (7.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (2.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.54e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (4.46e-4)" "unprognostic (3.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.12e-2)" TPSAB1 "TPS1, TPS2, TPSB1" ENSG00000172236 "Tryptase alpha/beta 1" Q15661 16 1240379-1242554 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 109 "granulocytes: 9687.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 900 "basophil: 90.0" "Lineage enriched" "Detected in single" 900 "granulocytes: 90.0" "Cancer enriched" "Detected in some" 29 "Leukemia: 82.8" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Breast - Fibroblasts, Colon - Mast cells, Lung - Mast cells, Skeletal muscle - Macrophages, Testis - Macrophages" "CAB016369, CAB022175, HPA049153, HPA049554" Supported Approved Vesicles "Secreted to blood" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" Vesicles "CAB016369: AB_628406, CAB022175: , HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (2.06e-2)" "unprognostic (5.14e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-2)" "unprognostic (9.31e-3)" "prognostic favorable (9.62e-6)" "unprognostic (1.02e-1)" "unprognostic (4.08e-2)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (2.83e-2)" "unprognostic (4.13e-2)" "unprognostic (2.23e-1)" "unprognostic (2.81e-2)" "unprognostic (1.16e-1)" "unprognostic (1.36e-2)" TPSB2 ENSG00000197253 "Tryptase beta 2" P20231 16 1227272-1230184 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 82 "granulocytes: 15633.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 51 "basophil: 5.0" "Lineage enriched" "Detected in single" 51 "granulocytes: 5.0" "Cancer enriched" "Detected in some" 38 "Leukemia: 59.2" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells, Skeletal muscle - Macrophages, Testis - Macrophages" "HPA049153, HPA049554" Supported "Secreted to blood" Enzyme NA NA 16000000 "Cluster 46: Basophils - Proteolysis" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" "HPA049153: AB_2680656, HPA049554: AB_2680815" "unprognostic (9.05e-2)" "unprognostic (8.46e-3)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (4.97e-3)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (8.55e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (8.30e-3)" "unprognostic (1.91e-2)" "unprognostic (5.76e-2)" "unprognostic (2.41e-2)" "unprognostic (4.65e-2)" "unprognostic (3.17e-2)" TPSD1 ENSG00000095917 "Tryptase delta 1" Q9BZJ3 16 1256059-1259008 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 20.6" "Cell type enriched" "Detected in some" 11 "granulocytes: 84.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 29 "basophil: 2.9" "Lineage enriched" "Detected in single" 29 "granulocytes: 2.9" "Cancer enriched" "Detected in single" 44 "Leukemia: 24.0" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells" "CAB002215, CAB032871, HPA040182, HPA049554" Supported "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" "CAB002215: AB_563870, CAB032871: AB_2206475, HPA040182: AB_2676875, HPA049554: AB_2680815" "unprognostic (5.99e-2)" "unprognostic (3.00e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-2)" "unprognostic (8.97e-3)" "unprognostic (1.15e-4)" "unprognostic (1.70e-1)" "unprognostic (5.45e-2)" "unprognostic (9.00e-2)" "unprognostic (2.88e-1)" "unprognostic (4.30e-1)" "unprognostic (2.94e-2)" "unprognostic (2.50e-3)" "unprognostic (3.74e-2)" "unprognostic (4.14e-1)" "unprognostic (3.89e-1)" "unprognostic (7.46e-3)" TPST1 TANGO13A ENSG00000169902 "Tyrosylprotein sulfotransferase 1" O60507 7 66205317-66420543 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 74.8;Excitatory neurons: 98.5;Inhibitory neurons: 102.7;Spermatocytes: 98.1" "Cancer enhanced" "Detected in all" "glioma: 36.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 52.5;neutrophil: 35.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047415, HPA061837" Approved Supported "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 9: Endometrial stromal cells - Transcription" "Golgi apparatus" "HPA047415: AB_10964056, HPA061837: AB_2732672" "unprognostic (7.46e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (3.43e-2)" "unprognostic (3.52e-2)" "unprognostic (1.78e-3)" "unprognostic (5.71e-2)" "unprognostic (8.21e-2)" "unprognostic (3.59e-1)" "unprognostic (9.25e-3)" "unprognostic (4.12e-2)" "unprognostic (4.98e-1)" "prognostic unfavorable (8.16e-6)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.48e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.73e-5)" TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521996-26596717 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 387.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 166.6;granulocytes: 137.4;NK-cells: 172.8;Plasma cells: 152.5;Syncytiotrophoblasts: 138.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" Enzyme NA NA 88000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Pancreas - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 77: Plasma cells - Protein processing" "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favorable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" TRABD2A "C2orf89, TIKI1" ENSG00000186854 "TraB domain containing 2A" Q86V40 2 84821650-84907008 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 41.4;lymphoid tissue: 11.1;ovary: 39.2" "Group enriched" "Detected in many" 4 "Early spermatids: 582.7;Late spermatids: 353.4" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 14.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 72.1" "Lineage enriched" "Detected in many" 18 "T-cells: 72.1" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 63.9;colorectal cancer: 35.7" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids" HPA045817 Approved "Intracellular and membrane" Enzyme NA NA 18000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 11: Late spermatids - Unknown function" "HPA045817: AB_2679460" "unprognostic (7.49e-3)" "unprognostic (3.35e-1)" "unprognostic (3.08e-1)" "unprognostic (3.29e-2)" "unprognostic (3.82e-5)" "unprognostic (2.46e-2)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "unprognostic (6.68e-2)" "unprognostic (1.66e-1)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.47e-4)" "unprognostic (4.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.41e-3)" "unprognostic (1.37e-1)" TRABD2B TIKI2 ENSG00000269113 "TraB domain containing 2B" A6NFA1 1 47760528-47997385 "Predicted intracellular proteins" "Wnt signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 6.4;Hepatocytes: 10.0;Lymphatic endothelial cells: 7.5;Microglial cells: 7.2;Proximal tubular cells: 20.1" "Cancer enriched" "Detected in many" 7 "renal cancer: 12.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.2" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA045817 Approved "Intracellular and membrane" Enzyme NA NA 41000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "HPA045817: AB_2679460" "unprognostic (2.38e-2)" "unprognostic (6.77e-2)" "unprognostic (1.19e-2)" "unprognostic (2.26e-2)" "unprognostic (5.65e-2)" "unprognostic (4.49e-2)" "unprognostic (3.16e-2)" "unprognostic (1.24e-1)" "unprognostic (2.74e-1)" "unprognostic (3.29e-3)" "unprognostic (1.84e-1)" "unprognostic (2.95e-1)" "unprognostic (1.41e-2)" "unprognostic (2.41e-2)" "unprognostic (4.77e-1)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" TREH "MGC129621, TRE, TREA" ENSG00000118094 Trehalase O43280 11 118657316-118679690 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 64.4" "Group enriched" "Detected in some" 16 "Late spermatids: 298.6;Proximal enterocytes: 185.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039913, HPA042045" Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" Enzyme NA NA 12000000 "Cluster 25: Small intestine - Absorption" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" Cytosol Vesicles "HPA039913: AB_10674988, HPA042045: AB_2677817" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (1.01e-2)" "unprognostic (5.22e-4)" "unprognostic (2.52e-1)" "unprognostic (9.83e-2)" "prognostic favorable (3.76e-4)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.33e-6)" "unprognostic (2.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" TREM1 "CD354, TREM-1" ENSG00000124731 "Triggering receptor expressed on myeloid cells 1" Q9NP99 6 41267926-41286682 "CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.0;lung: 63.3;lymphoid tissue: 42.9" "Group enriched" "Detected in some" 4 "Hofbauer cells: 121.6;Macrophages: 117.6;monocytes: 389.2" "Cancer enhanced" "Detected in many" "lung cancer: 9.6" "Region enhanced" "Detected in many" "cerebral cortex: 16.3" "Immune cell enriched" "Detected in many" 7 "neutrophil: 616.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 616.7" "Cancer enhanced" "Detected in some" "testis cancer: 5.7" "Adipose visceral - Neutrophils, Colon - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005563, HPA053612" Approved Approved "Golgi apparatus" "Secreted to blood" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus" "HPA005563: AB_1858259, HPA053612: " "unprognostic (6.41e-2)" "unprognostic (1.47e-3)" "unprognostic (1.22e-1)" "unprognostic (3.39e-2)" "unprognostic (6.07e-3)" "unprognostic (2.97e-2)" "unprognostic (5.73e-5)" "unprognostic (1.29e-1)" "unprognostic (1.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.24e-3)" "unprognostic (7.65e-2)" "unprognostic (3.18e-7)" "unprognostic (6.32e-3)" "unprognostic (4.95e-2)" "unprognostic (1.08e-1)" "unprognostic (7.26e-2)" TREM2 "TREM-2, Trem2a, Trem2b, Trem2c" ENSG00000095970 "Triggering receptor expressed on myeloid cells 2" Q9NZC2 6 41158506-41163186 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.5;choroid plexus: 56.7" "Cell type enriched" "Detected in some" 8 "Hofbauer cells: 905.9" "Cancer enhanced" "Detected in all" "glioma: 93.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.0" "Lineage enhanced" "Detected in single" "dendritic cells: 2.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4;Leukemia: 2.6;testis cancer: 1.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Sebaceous gland cells, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010917, HPA012571" Approved Uncertain Vesicles "Secreted in brain" Receptor NA NA 50000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 3 Vesicles "HPA010917: AB_1080365, HPA012571: AB_1858260" "unprognostic (3.89e-1)" "unprognostic (4.44e-3)" "unprognostic (2.77e-2)" "unprognostic (1.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.53e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (4.83e-2)" "unprognostic (1.07e-1)" "unprognostic (8.57e-3)" "unprognostic (1.33e-1)" "unprognostic (2.09e-1)" "unprognostic (3.58e-3)" "unprognostic (8.04e-2)" "unprognostic (1.04e-2)" "unprognostic (3.16e-3)" "unprognostic (1.85e-2)" TREML4 TLT4 ENSG00000188056 "Triggering receptor expressed on myeloid cells like 4" Q6UXN2 6 41228339-41238882 "Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "choroid plexus: 2.0" "Cell type enhanced" "Detected in single" "monocytes: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "choroid plexus: 3.5" "Group enriched" "Detected in some" 4 "eosinophil: 4.5;neutrophil: 8.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.3" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils" "Not detected" "Not detected" HPA065044 Uncertain Approved "Plasma membrane" "Secreted - unknown location" Immunity NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "HPA065044: AB_2685411" "unprognostic (1.49e-1)" "unprognostic (1.51e-1)" "unprognostic (5.58e-2)" "unprognostic (2.07e-1)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (9.50e-3)" "unprognostic (1.18e-4)" "unprognostic (1.05e-3)" "unprognostic (1.32e-1)" "unprognostic (5.26e-2)" "unprognostic (1.21e-2)" TRH ENSG00000170893 "Thyrotropin releasing hormone" P20396 3 129974688-129977935 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 56.5;cervix: 25.1;endometrium 1: 18.2;retina: 34.2" "Cell type enriched" "Detected in some" 8 "Muller glia cells: 201.4" "Group enriched" "Detected in some" 5 "breast cancer: 13.3;endometrial cancer: 10.2;glioma: 4.3" "Group enriched" "Detected in many" 6 "hypothalamus: 139.3;medulla oblongata: 131.2;pons: 82.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Leukemia: 4.3" "Group enriched" "Detected in many" 5 "hypothalamus: 175.6;olfactory bulb: 148.0" "Low region specificity" "Detected in many" HPA035596 Enhanced "Secreted in other tissues" Hormone NA NA "Cluster 76: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 10: Muller glia cells - Visual perception" 2 "HPA035596: AB_2674695" "unprognostic (1.22e-1)" "unprognostic (8.94e-2)" "unprognostic (5.82e-3)" "unprognostic (5.24e-2)" "unprognostic (2.82e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (4.44e-2)" "unprognostic (3.86e-2)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" TRIM24 "hTIF1, RNF82, TIF1, Tif1a" ENSG00000122779 "Tripartite motif containing 24" O15164 7 138460259-138589996 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043495, HPA061717" Approved Enhanced Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 2 Nucleoplasm "HPA043495: AB_10962915, HPA061717: AB_2684592" "unprognostic (2.40e-1)" "unprognostic (9.52e-3)" "unprognostic (2.23e-1)" "unprognostic (3.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.94e-4)" "prognostic favorable (6.57e-4)" "unprognostic (4.01e-2)" "unprognostic (8.93e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-1)" "unprognostic (4.62e-2)" "unprognostic (1.62e-1)" "unprognostic (2.25e-2)" "unprognostic (5.54e-2)" "unprognostic (6.34e-2)" TRIM28 "KAP-1, KAP1, PPP1R157, RNF96, TF1B, TIF1-beta, TIF1B, TIF1beta" ENSG00000130726 "Tripartite motif containing 28" Q13263 19 58544064-58550722 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010066, HPA064033" Supported Enhanced Nucleoplasm "Intracellular and membrane" Transcription NA NA 140000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 4: Testis - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 13 Nucleoplasm "CAB010066: AB_2209905, HPA064033: AB_2685179" "unprognostic (2.76e-1)" "unprognostic (1.40e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (1.85e-6)" "unprognostic (1.20e-2)" "unprognostic (2.10e-2)" "unprognostic (2.66e-1)" "unprognostic (4.92e-3)" "unprognostic (9.28e-2)" "unprognostic (2.47e-2)" "unprognostic (4.67e-2)" "unprognostic (7.34e-2)" "unprognostic (4.22e-1)" "unprognostic (3.28e-2)" TSHB ENSG00000134200 "Thyroid stimulating hormone subunit beta" P01222 1 115029826-115034302 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2636 "pituitary gland: 1711.1" "Group enriched" "Detected in some" 12 "Early spermatids: 1.1;Late spermatids: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Not detected" "Not detected" "CAB022202, HPA042681, CAB080112" Enhanced "Secreted to blood" Hormone NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Late spermatids - Unknown function" "CAB022202: , CAB080112: , HPA042681: AB_2732500" "unprognostic (2.14e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" TSHR LGR3 ENSG00000165409 "Thyroid stimulating hormone receptor" P16473 14 80954989-81146306 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "thyroid gland: 265.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 6.7;Inhibitory neurons: 11.8;Langerhans cells: 7.2;Microglial cells: 6.3;Oligodendrocytes: 8.8;Plasma cells: 14.3" "Cancer enriched" "Detected in some" 116 "thyroid cancer: 100.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "naive B-cell: 1.7;T-reg: 6.9" "Group enriched" "Detected in many" 5 "B-cells: 1.7;T-cells: 6.9" "Cancer enhanced" "Detected in some" "Myeloma: 10.0" "Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "hypothalamus: 1.8" CAB000473 Approved "Intracellular and membrane" Receptor NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 61: Plasma cells - Immunoglobulins & histones" 4 "CAB000473: AB_2303782" "unprognostic (3.36e-3)" "unprognostic (1.31e-3)" "unprognostic (1.02e-2)" "unprognostic (4.17e-6)" "unprognostic (3.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.83e-1)" "unprognostic (2.66e-2)" "unprognostic (3.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" "unprognostic (7.11e-3)" "unprognostic (5.08e-7)" "unprognostic (1.32e-1)" "unprognostic (7.40e-2)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" TSKU "E2IG4, LRRC54, TSK" ENSG00000182704 "Tsukushi, small leucine rich proteoglycan" Q8WUA8 11 76782251-76798153 "Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 230.2" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 433.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008164 Approved Approved "Nucleoplasm,Nuclear bodies" "Secreted to blood" "Developmental protein" NA NA 6200000 "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" Nucleoplasm "Nuclear bodies" "HPA008164: AB_1853327" "unprognostic (1.07e-2)" "unprognostic (2.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (3.66e-4)" "unprognostic (7.05e-2)" "unprognostic (2.39e-1)" "unprognostic (3.08e-1)" "unprognostic (2.17e-3)" "unprognostic (4.81e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (2.87e-4)" "prognostic favorable (1.66e-4)" "prognostic unfavorable (2.80e-8)" "unprognostic (1.47e-1)" "unprognostic (4.93e-2)" "unprognostic (6.71e-2)" "unprognostic (3.88e-2)" TSLP ENSG00000145777 "Thymic stromal lymphopoietin" Q969D9 5 111070062-111078026 "FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 11.2;urinary bladder: 11.5" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 102.0;Basal squamous epithelial cells: 211.4" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "thalamus: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" HPA056350 Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" Cytokine NA NA 38400 "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Golgi apparatus, Vesicles" "HPA056350: " "unprognostic (6.47e-4)" "unprognostic (3.26e-1)" "unprognostic (6.57e-2)" "unprognostic (1.93e-1)" "unprognostic (5.03e-2)" "unprognostic (7.72e-2)" "unprognostic (1.21e-1)" "unprognostic (2.53e-2)" "unprognostic (5.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-1)" "unprognostic (1.88e-1)" "unprognostic (5.04e-2)" "unprognostic (1.95e-1)" "unprognostic (2.76e-1)" "unprognostic (1.74e-3)" TSPEAR "C21orf29, DFNB98, MGC11251, TSP-EAR" ENSG00000175894 "Thrombospondin type laminin G domain and EAR repeats" Q8WU66 21 44497893-44711572 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 1.2;Early spermatids: 2.5;Excitatory neurons: 1.1;Late spermatids: 1.6;Lymphatic endothelial cells: 1.2;Oocytes: 3.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.8" "Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.3" "CAB034203, CAB034204, HPA052995" Uncertain "Secreted in other tissues" Other NA NA "Cluster 21: Testis - Unknown function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 21: Early spermatids - Spermatogenesis" "CAB034203: AB_1567654, CAB034204: AB_1567655, HPA052995: AB_2682008" "unprognostic (8.61e-3)" "unprognostic (2.45e-1)" "unprognostic (1.86e-4)" "unprognostic (7.87e-3)" "unprognostic (4.08e-2)" "unprognostic (1.00e-3)" "unprognostic (7.92e-3)" "unprognostic (1.56e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-2)" "unprognostic (3.86e-4)" "unprognostic (2.13e-2)" "unprognostic (4.80e-7)" "unprognostic (2.08e-1)" "unprognostic (1.69e-1)" "unprognostic (1.88e-2)" "unprognostic (2.98e-2)" TTC19 "FLJ20343, MGC19520" ENSG00000011295 "Tetratricopeptide repeat domain 19" Q6DKK2 17 15999784-16045015 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023010, HPA052380" Enhanced Enhanced Mitochondria "Intracellular and membrane" Transport NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 42: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" 33 Mitochondria "HPA023010: AB_1858429, HPA052380: AB_2681806" "unprognostic (1.04e-2)" "unprognostic (4.90e-3)" "unprognostic (2.87e-2)" "unprognostic (4.80e-3)" "unprognostic (8.09e-2)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.84e-2)" "unprognostic (8.34e-2)" "unprognostic (1.72e-2)" "unprognostic (2.30e-3)" "unprognostic (5.14e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.31e-1)" "unprognostic (3.22e-1)" "unprognostic (4.85e-2)" "unprognostic (2.24e-1)" TTC9B FLJ30373 ENSG00000174521 "Tetratricopeptide repeat domain 9B" Q8N6N2 19 40216058-40218384 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "brain: 167.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 30.0;Excitatory neurons: 37.9;Horizontal cells: 35.3;Inhibitory neurons: 18.9;Oligodendrocyte precursor cells: 25.5" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 20 "Neuroblastoma: 27.0" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042496 Approved Approved Nucleoplasm,Vesicles,Mitochondria "Secreted in brain" "No annotated function" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Mitochondria" Vesicles "HPA042496: AB_10795506" "unprognostic (2.31e-1)" "unprognostic (1.39e-4)" "unprognostic (5.09e-2)" "unprognostic (5.24e-2)" "unprognostic (8.47e-2)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (7.95e-2)" "unprognostic (2.78e-1)" "unprognostic (1.54e-2)" "unprognostic (3.69e-1)" "unprognostic (8.75e-6)" "unprognostic (1.39e-1)" "unprognostic (8.23e-2)" "unprognostic (1.95e-1)" "unprognostic (5.24e-2)" TTR "CTS, CTS1, HsT2651, PALB" ENSG00000118271 Transthyretin P02766 18 31557009-31598833 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Transport "Hormone, Thyroid hormone" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "choroid plexus: 692067.5" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 26585.9" "Group enriched" "Detected in many" 28 "liver cancer: 928.2;pancreatic cancer: 666.0" "Region enriched" "Detected in all" 82 "choroid plexus: 302089.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Gastric cancer: 130.8;liver cancer: 177.5" "Liver - Hepatocytes, Pancreas - Alpha cells, Testis - Early spermatids" "Group enriched" "Detected in all" 5 "basal ganglia: 1538.8;hippocampal formation: 4894.4;pons and medulla: 5760.6;thalamus: 3403.0" "Region enhanced" "Detected in all" "medulla oblongata: 1291.2" "CAB002517, HPA002550, CAB062567, CAB073406" Supported Approved "Golgi apparatus" "Secreted to blood" Hormone NA NA 345000000000 99000000000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 56 "Golgi apparatus" "CAB002517: AB_563965, CAB062567: AB_2665620, CAB073406: , HPA002550: AB_1080419" "unprognostic (6.79e-3)" "unprognostic (3.38e-2)" "unprognostic (4.10e-1)" "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (8.15e-2)" "unprognostic (3.74e-2)" "unprognostic (9.66e-3)" "unprognostic (8.72e-2)" "unprognostic (1.23e-2)" "unprognostic (8.35e-3)" "unprognostic (5.26e-1)" "unprognostic (3.52e-2)" TUB rd5 ENSG00000166402 "TUB bipartite transcription factor" P50607 11 8019244-8106243 "Disease related genes, Predicted intracellular proteins" "Phagocytosis, Sensory transduction" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 80.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 51.0;Excitatory neurons: 33.5;Horizontal cells: 24.5;Rod photoreceptor cells: 82.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 50.5" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017997, HPA049019" Enhanced Approved "Nucleoli,Centriolar satellite" "Intracellular and membrane" Other NA NA "Cluster 76: Retina - Visual perception" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" "Centriolar satellite" Nucleoli "HPA017997: AB_1858449, HPA049019: AB_2680601" "unprognostic (2.53e-1)" "unprognostic (7.23e-2)" "unprognostic (1.80e-2)" "unprognostic (4.06e-2)" "unprognostic (9.62e-2)" "unprognostic (1.47e-2)" "unprognostic (1.53e-2)" "unprognostic (2.53e-1)" "unprognostic (9.71e-2)" "unprognostic (5.08e-2)" "prognostic favorable (2.85e-4)" "unprognostic (4.18e-1)" "prognostic favorable (2.35e-5)" "unprognostic (8.37e-3)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (1.39e-2)" TUFT1 ENSG00000143367 "Tuftelin 1" Q9NNX1 1 151540305-151583583 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 104.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 57.8;Glandular and luminal cells: 71.5;Suprabasal keratinocytes: 61.5;Syncytiotrophoblasts: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 5 "granulocytes: 5.2;T-cells: 3.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 50.7" "HPA028112, HPA054301" Approved Approved Approved Vesicles "Secreted - unknown location" Other NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 13: Skin - Cornification" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 5 Vesicles "HPA028112: AB_10603224, HPA054301: AB_2682442" "unprognostic (6.16e-2)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.83e-4)" "unprognostic (4.49e-3)" "unprognostic (1.12e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-2)" "unprognostic (8.29e-3)" "unprognostic (9.06e-2)" "unprognostic (6.70e-3)" "unprognostic (7.88e-2)" "unprognostic (2.58e-3)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (1.82e-3)" "unprognostic (4.53e-2)" TULP1 "LCA15, RP14, TUBL1" ENSG00000112041 "TUB like protein 1" O00294 6 35497874-35512896 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Sensory transduction, Vision" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 172 "retina: 202.7" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 535.2;Rod photoreceptor cells: 346.7" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Brain cancer: 1.0" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Other NA NA "Cluster 76: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 2 "unprognostic (7.98e-2)" "unprognostic (2.33e-2)" "unprognostic (4.38e-2)" "unprognostic (4.60e-5)" "unprognostic (2.28e-2)" "unprognostic (3.12e-3)" "unprognostic (3.30e-1)" "unprognostic (5.49e-3)" "unprognostic (1.85e-1)" "unprognostic (2.66e-2)" "unprognostic (7.42e-2)" "unprognostic (1.66e-6)" "unprognostic (1.72e-1)" "unprognostic (1.30e-1)" "unprognostic (5.42e-2)" "unprognostic (4.11e-2)" TULP2 "CT65, TUBL2" ENSG00000104804 "TUB like protein 2" O00295 19 48880965-48898744 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 30.4" "Group enriched" "Detected in some" 24 "Early spermatids: 368.4;Late spermatids: 230.9" "Cancer enriched" "Detected in single" 8 "testis cancer: 1.5" "Region enhanced" "Detected in many" "cerebral cortex: 6.4" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 13 "dendritic cells: 1.3" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075828 Approved Cytosol "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 53: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 18: Early spermatids - Unknown function" Cytosol "HPA075828: " "unprognostic (9.97e-2)" "unprognostic (5.55e-3)" "unprognostic (1.15e-1)" "unprognostic (9.39e-2)" "unprognostic (1.69e-4)" "unprognostic (6.79e-4)" "unprognostic (1.07e-2)" "unprognostic (2.57e-1)" "unprognostic (5.94e-3)" "unprognostic (1.08e-2)" "unprognostic (9.82e-2)" "unprognostic (1.33e-1)" "unprognostic (4.59e-4)" "unprognostic (6.37e-2)" "unprognostic (1.63e-1)" "unprognostic (1.08e-1)" "unprognostic (1.97e-1)" TULP3 TUBL3 ENSG00000078246 "TUB like protein 3" O75386 12 2877223-2941138 "Disease related genes, Predicted intracellular proteins" "Developmental protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 66.9;Oocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015285, HPA018496" Uncertain Supported "Nucleoplasm,Nucleoli,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 6: Ovarian stromal cells - Transcription" 15 Nucleoplasm "Nucleoli, Plasma membrane" "HPA015285: AB_1858460, HPA018496: AB_2669889" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (4.80e-2)" "prognostic favorable (2.99e-4)" "unprognostic (2.45e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.44e-1)" "unprognostic (4.09e-2)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (7.52e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-2)" "unprognostic (3.19e-2)" TWSG1 TSG ENSG00000128791 "Twisted gastrulation BMP signaling modulator 1" Q9GZX9 18 9334767-9402420 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 198.1;Peritubular cells: 89.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014898 Uncertain Supported Centrosome,Cytosol "Secreted - unknown location" "Developmental protein" No No 3500000 "Cluster 30: Non-specific - DNA binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 55: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 7 "Centrosome, Cytosol" "HPA014898: AB_1858467" "unprognostic (2.55e-1)" "unprognostic (3.17e-2)" "unprognostic (7.31e-2)" "unprognostic (8.95e-3)" "unprognostic (2.92e-3)" "unprognostic (1.83e-1)" "unprognostic (8.29e-2)" "unprognostic (5.88e-2)" "unprognostic (6.33e-2)" "unprognostic (1.05e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (4.36e-2)" "unprognostic (8.73e-2)" "unprognostic (1.79e-1)" "unprognostic (1.32e-2)" TXN "TRX, Trx80" ENSG00000136810 Thioredoxin P10599 9 110243810-110256507 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transcription, Transcription regulation, Transport" Activator Allergen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1029.0" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 3519.5;Proximal tubular cells: 3360.9;Squamous epithelial cells: 3040.1;Suprabasal keratinocytes: 4072.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1646.2;granulocytes: 1359.5" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB008678, HPA047478, HPA055752" Enhanced Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" Transport NA NA 16000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 14: Langerhans cells - Innate immune response" 26 "Nucleoplasm, Cytosol" "CAB008678: AB_1623676, HPA047478: AB_2680063, HPA055752: AB_2682907" "unprognostic (2.12e-2)" "unprognostic (1.27e-1)" "unprognostic (9.77e-2)" "prognostic favorable (3.40e-6)" "unprognostic (1.80e-2)" "unprognostic (2.13e-2)" "unprognostic (5.52e-3)" "unprognostic (1.37e-2)" "unprognostic (1.75e-1)" "unprognostic (3.36e-2)" "unprognostic (5.93e-3)" "unprognostic (1.66e-1)" "unprognostic (4.96e-3)" "unprognostic (7.80e-2)" "unprognostic (8.55e-2)" "unprognostic (2.99e-2)" "unprognostic (8.51e-2)" TXNDC12 "AGR1, ERP18, ERP19, hAG-1, PDIA16, TLP19" ENSG00000117862 "Thioredoxin domain containing 12" O95881 1 52020131-52055191 "Enzymes, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA 160000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 49: Non-specific - Transcription" 8 "unprognostic (6.54e-2)" "unprognostic (5.46e-2)" "prognostic favorable (4.44e-4)" "unprognostic (2.33e-3)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.61e-4)" "prognostic unfavorable (1.28e-5)" "unprognostic (1.25e-1)" "unprognostic (3.28e-2)" "unprognostic (1.17e-1)" "unprognostic (6.14e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.40e-12)" "unprognostic (2.13e-1)" "unprognostic (5.83e-2)" "unprognostic (1.73e-2)" "unprognostic (1.17e-1)" TXNDC16 KIAA1344 ENSG00000087301 "Thioredoxin domain containing 16" Q9P2K2 14 52430596-52552522 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 122.7;Inhibitory neurons: 84.8" "Cancer enhanced" "Detected in all" "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002543 Approved Approved Mitochondria "Secreted to blood" "No annotated function" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 53: Non-specific - Glycosylation" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 37: Glandular & Luminal cells - Unknown function" Mitochondria "HPA002543: AB_1079199" "unprognostic (1.37e-1)" "unprognostic (7.79e-3)" "unprognostic (5.95e-3)" "unprognostic (2.36e-1)" "unprognostic (5.95e-3)" "unprognostic (9.73e-2)" "unprognostic (2.50e-1)" "unprognostic (1.43e-2)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.07e-2)" "unprognostic (1.21e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (3.55e-3)" "unprognostic (2.04e-1)" TXNDC5 "EndoPDI, ERp46, FLJ21353, FLJ90810, Hcc-2, MGC3178, PDIA15" ENSG00000239264 "Thioredoxin domain containing 5" Q8NBS9 6 7881517-7910788 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Isomerase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 13 "Plasma cells: 755.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "memory B-cell: 13.0;naive B-cell: 6.9;plasmacytoid DC: 26.8" "Group enriched" "Detected in many" 21 "B-cells: 13.0;dendritic cells: 26.8" "Cancer enriched" "Detected in all" 6 "Myeloma: 2947.3" "Breast - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034677, HPA034678" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 6900000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" 2 "Endoplasmic reticulum" "HPA034677: AB_2674275, HPA034678: AB_2674276" "unprognostic (3.15e-1)" "unprognostic (1.09e-2)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" "unprognostic (6.95e-2)" "unprognostic (1.20e-2)" "unprognostic (6.07e-2)" "unprognostic (5.81e-2)" "unprognostic (3.56e-2)" "unprognostic (1.54e-1)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.05e-1)" "unprognostic (7.98e-2)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" UBXN8 "D8S2298E, REP8, UBXD6" ENSG00000104691 "UBX domain protein 8" O00124 8 30729131-30767006 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 120.3" "Cell type enhanced" "Detected in all" "Early spermatids: 134.5;Granulosa cells: 81.3;Late spermatids: 209.4;Ovarian stromal cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017725, HPA077538" Enhanced Supported "Nucleoplasm,Nucleoli,Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 16: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 6: Ovarian stromal cells - Transcription" 7 "Endoplasmic reticulum" "Nucleoplasm, Nucleoli" "HPA017725: AB_1847462, HPA077538: AB_2686844" "unprognostic (3.00e-2)" "unprognostic (2.30e-1)" "prognostic favorable (6.13e-4)" "unprognostic (7.71e-2)" "unprognostic (2.24e-1)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (1.84e-2)" "unprognostic (1.90e-1)" "unprognostic (5.13e-2)" "unprognostic (1.58e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.25e-5)" "unprognostic (2.49e-1)" "unprognostic (1.96e-1)" "unprognostic (1.51e-1)" "unprognostic (6.88e-2)" UCMA "C10orf49, GRP" ENSG00000165623 "Upper zone of growth plate and cartilage matrix associated" Q8WVF2 10 13221766-13234374 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.5" "Cell type enriched" "Detected in some" 68 "Oocytes: 127.2" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.7" "Group enriched" "Detected in some" 18 "amygdala: 2.1;cerebral cortex: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046718 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 20000 "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 44: Oocytes - Unknown function" "HPA046718: AB_2679771" "unprognostic (4.25e-1)" UCN "UCN1, UI, UROC" ENSG00000163794 Urocortin P55089 2 27307400-27308445 "Predicted secreted proteins" Hearing Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.5" "Cell type enhanced" "Detected in many" "Astrocytes: 7.4;Cholangiocytes: 5.7;Excitatory neurons: 6.3;Oligodendrocytes: 5.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 3.3" CAB010911 Approved Approved "Endoplasmic reticulum" "Secreted to blood" Hormone NA NA 133000 "Cluster 33: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 65: Neurons - Synaptic function" 1 "Endoplasmic reticulum" "CAB010911: AB_261834" "unprognostic (7.35e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.42e-2)" "unprognostic (5.08e-2)" "unprognostic (7.72e-2)" "unprognostic (5.69e-3)" "unprognostic (2.66e-1)" "unprognostic (2.48e-1)" "unprognostic (1.15e-1)" "unprognostic (3.80e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.84e-7)" "unprognostic (4.84e-2)" "unprognostic (3.87e-2)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" UCN2 "SRP, UCN-II, UCNI, URP" ENSG00000145040 "Urocortin 2" Q96RP3 3 48561718-48563781 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 12.8;vagina: 4.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.5;Basal respiratory cells: 1.4" "Cancer enriched" "Detected in many" 5 "melanoma: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "skin cancer: 119.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA066841 Uncertain Approved Vesicles "Secreted to blood" Hormone NA NA 98600 "Cluster 13: Skin - Cornification" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Squamous epithelial cells - Keratinization" Vesicles "HPA066841: AB_2685735" "unprognostic (7.98e-2)" "unprognostic (1.35e-1)" "unprognostic (4.80e-2)" "unprognostic (1.96e-2)" "unprognostic (2.39e-2)" "unprognostic (4.26e-2)" "unprognostic (1.92e-3)" "unprognostic (2.02e-3)" "unprognostic (1.62e-1)" "unprognostic (2.93e-3)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (3.34e-14)" "unprognostic (4.39e-2)" "unprognostic (2.75e-1)" "unprognostic (1.36e-1)" "unprognostic (2.88e-2)" UCN3 "SPC, UCNIII" ENSG00000178473 "Urocortin 3" Q969E3 10 5364966-5374692 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 8.5;pancreas: 5.6;pituitary gland: 2.6;stomach 1: 3.3" "Cell type enriched" "Detected in some" 5 "Enteroendocrine cells: 240.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.4" "Group enriched" "Detected in some" 7 "basal ganglia: 2.5;hypothalamus: 1.7;medulla oblongata: 4.1;midbrain: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "breast cancer: 1.1;lung cancer: 3.0;pancreatic cancer: 1.0;thyroid cancer: 3.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Region enhanced" "Detected in some" "hypothalamus: 5.1" HPA038281 Uncertain "Secreted to blood" Hormone NA NA "Cluster 45: Intestine - Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA038281: AB_10672408" "unprognostic (2.00e-2)" "unprognostic (2.31e-1)" "unprognostic (1.60e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-3)" "unprognostic (8.42e-2)" "unprognostic (3.55e-2)" "unprognostic (2.91e-2)" UGGT2 "FLJ10873, FLJ11485, HUGT2, MGC117360, MGC150689, MGC87276, UGCGL2" ENSG00000102595 "UDP-glucose glycoprotein glucosyltransferase 2" Q9NYU1 13 95801580-96053482 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 106.2;Excitatory neurons: 207.8;Inhibitory neurons: 162.6;Microglial cells: 73.4;Oligodendrocyte precursor cells: 196.2;Oligodendrocytes: 193.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 5.9;eosinophil: 2.6;intermediate monocyte: 6.2;myeloid DC: 3.6;non-classical monocyte: 6.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047955 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 73: Breast - Lactation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 19: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA047955: AB_2680222" "unprognostic (5.32e-2)" "unprognostic (2.56e-1)" "unprognostic (2.51e-2)" "unprognostic (1.83e-1)" "unprognostic (9.33e-2)" "unprognostic (8.70e-2)" "prognostic unfavorable (9.99e-4)" "prognostic unfavorable (5.47e-4)" "unprognostic (1.55e-1)" "unprognostic (9.21e-2)" "unprognostic (7.75e-3)" "unprognostic (6.27e-2)" "unprognostic (5.65e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (9.61e-2)" "unprognostic (1.61e-2)" UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636448-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 21.2;intestine: 76.9;stomach 1: 31.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.8;Distal enterocytes: 1.9;Gastric mucus-secreting cells: 4.7;Intestinal goblet cells: 1.2;Paneth cells: 1.4;Proximal enterocytes: 3.3;Squamous epithelial cells: 4.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 81.8;Gallbladder cancer: 131.7;pancreatic cancer: 71.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" UGT2B28 ENSG00000135226 "UDP glucuronosyltransferase family 2 member B28" Q9BY64 4 69280475-69295050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "breast: 193.8" "Cell type enriched" "Detected in single" 32 "Cholangiocytes: 11.4" "Cancer enriched" "Detected in single" 8 "breast cancer: 1.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enriched" "Detected in single" 9 "prostate cancer: 4.1" HPA045108 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 73: Breast - Lactation" "Cluster 60: Prostate cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" "HPA045108: AB_2679218" "unprognostic (1.81e-1)" "unprognostic (1.40e-1)" "unprognostic (7.20e-3)" "unprognostic (1.51e-2)" "unprognostic (4.37e-5)" "unprognostic (9.79e-4)" UGT2B4 UGT2B11 ENSG00000156096 "UDP glucuronosyltransferase family 2 member B4" P06133 4 69480165-69526014 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 107 "liver: 1234.7" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 806.8" "Cancer enriched" "Detected in some" 96 "liver cancer: 351.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "liver cancer: 32.2" "Liver - Hepatocytes" "CAB033260, HPA045108" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "CAB033260: AB_2241496, HPA045108: AB_2679218" "unprognostic (7.46e-2)" "unprognostic (1.50e-1)" "unprognostic (9.37e-2)" "unprognostic (1.51e-1)" "unprognostic (2.47e-2)" "unprognostic (1.47e-1)" "unprognostic (9.43e-3)" "unprognostic (3.52e-1)" ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 5.9" "Cell type enhanced" "Detected in many" "Adipocytes: 25.5;Basal respiratory cells: 16.4;Late spermatids: 10.8;Squamous epithelial cells: 12.0;T-cells: 9.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" Immunity NA NA "Cluster 1: T-cells - Unknown function" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" ULBP3 RAET1N ENSG00000131019 "UL16 binding protein 3" Q9BZM4 6 150061053-150069121 "Predicted intracellular proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 6.3;testis: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 7.6;Alveolar cells type 1: 5.4;Gastric mucus-secreting cells: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "HPA056541, HPA063007" Approved Uncertain "Vesicles,Centriolar satellite" "Intracellular and membrane" Immunity NA NA "Cluster 1: T-cells - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 Vesicles "Centriolar satellite" "HPA056541: , HPA063007: AB_2684920" "unprognostic (4.87e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (2.99e-2)" "unprognostic (8.47e-2)" "unprognostic (1.96e-1)" "unprognostic (5.87e-2)" "unprognostic (8.71e-2)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (6.26e-2)" "unprognostic (3.43e-1)" "unprognostic (2.12e-1)" "unprognostic (5.45e-2)" "unprognostic (5.16e-2)" UMOD ENSG00000169344 Uromodulin P07911 16 20333051-20356301 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 689 "kidney: 2197.0" "Group enriched" "Detected in some" 164 "Collecting duct cells: 204.2;Distal tubular cells: 405.7" "Cancer enriched" "Detected in single" 39 "renal cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009446, HPA043420, HPA054721" Enhanced "Secreted in other tissues" Immunity NA NA 55000000 66000000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 39: Non-specific - Basic cellular processes" "CAB009446: AB_2212378, HPA043420: AB_2678474, HPA054721: AB_2682585" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (6.45e-2)" "unprognostic (3.02e-2)" "unprognostic (1.49e-2)" "unprognostic (1.43e-1)" USH2A "RP39, USH2" ENSG00000042781 Usherin O75445 1 215622891-216423448 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "liver: 6.7;retina: 18.6" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 98.6;Early spermatids: 59.1;Rod photoreceptor cells: 188.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Intracellular and membrane" Other NA NA "Cluster 76: Retina - Visual perception" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" "unprognostic (3.92e-3)" "unprognostic (1.74e-1)" "unprognostic (2.97e-2)" "unprognostic (5.38e-2)" "unprognostic (9.19e-2)" "unprognostic (2.04e-1)" "unprognostic (6.62e-4)" "unprognostic (1.00e-1)" "unprognostic (3.68e-1)" "unprognostic (2.06e-1)" "unprognostic (6.07e-3)" "unprognostic (3.15e-2)" "unprognostic (3.28e-11)" "unprognostic (2.02e-2)" "unprognostic (1.91e-1)" "unprognostic (3.35e-2)" "unprognostic (9.09e-4)" USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232866-47248328 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 165.3" "Cell type enhanced" "Detected in all" "Bipolar cells: 167.0;Horizontal cells: 140.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 25: Bipolar cells - Visual perception" 10 Nucleoplasm Cytosol "HPA003103: AB_10671088, HPA037536: AB_10672904" "unprognostic (1.60e-1)" "unprognostic (2.77e-3)" "unprognostic (5.84e-2)" "prognostic unfavorable (2.95e-4)" "unprognostic (3.08e-2)" "unprognostic (2.02e-1)" "unprognostic (6.11e-3)" "unprognostic (9.21e-2)" "unprognostic (3.18e-2)" "unprognostic (3.52e-1)" "unprognostic (3.29e-3)" "unprognostic (3.74e-2)" "prognostic favorable (4.13e-5)" "unprognostic (3.14e-2)" "unprognostic (9.23e-2)" "unprognostic (9.51e-2)" "unprognostic (7.11e-2)" USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053275, HPA060513, HPA077975" Supported "Nucleoplasm,Midbody ring" "Intracellular and membrane" Enzyme Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 29: Monocytes - Innate immune response" Nucleoplasm "Midbody ring" "HPA053275: AB_2682096, HPA060513: AB_2684299, HPA077975: AB_2732365" "unprognostic (4.63e-3)" "unprognostic (2.71e-1)" "unprognostic (7.88e-2)" "unprognostic (3.33e-2)" "unprognostic (2.16e-2)" "unprognostic (6.03e-2)" "unprognostic (6.26e-2)" "unprognostic (4.52e-2)" "unprognostic (1.62e-2)" "unprognostic (2.36e-1)" "unprognostic (3.54e-2)" "unprognostic (4.87e-2)" "unprognostic (1.17e-1)" "unprognostic (8.61e-2)" "unprognostic (2.78e-1)" "unprognostic (6.21e-2)" "prognostic favorable (1.38e-4)" UTS2 "PRO1068, U-II, UCN2, UII" ENSG00000049247 "Urotensin 2" O95399 1 7843083-7853512 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 3.6;brain: 8.4" "Group enriched" "Detected in some" 4 "NK-cells: 52.7;T-cells: 13.3" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 6 "medulla oblongata: 99.2;pons: 59.5;white matter: 50.5" "Immune cell enriched" "Detected in many" 5 "T-reg: 45.4" "Lineage enriched" "Detected in many" 5 "T-cells: 45.4" "Cancer enriched" "Detected in many" 9 "Bone cancer: 52.5" "Region enriched" "Detected in single" 19 "pons and medulla: 6.1" "Region enriched" "Detected in some" 12 "spinal cord: 99.2" HPA017000 Uncertain "Secreted to blood" Hormone NA NA 2590000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 19: NK-cells - Adaptive immune response" "HPA017000: AB_1858656" "unprognostic (2.10e-3)" "unprognostic (1.35e-1)" "unprognostic (3.89e-3)" "unprognostic (1.33e-3)" "unprognostic (2.32e-5)" "unprognostic (1.09e-4)" "unprognostic (4.95e-2)" "unprognostic (6.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.65e-2)" "unprognostic (1.28e-1)" "unprognostic (1.89e-1)" "unprognostic (2.52e-5)" "unprognostic (1.75e-1)" "unprognostic (1.44e-1)" "unprognostic (2.47e-1)" "unprognostic (3.30e-3)" UTS2B "U2B, URP, UTS2D" ENSG00000188958 "Urotensin 2B" Q765I0 3 191267168-191330526 "Predicted secreted proteins" Hormone "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.3;retina: 6.1" "Cell type enhanced" "Detected in some" "B-cells: 2.2;Early spermatids: 7.9;Granulosa cells: 2.2;Late spermatids: 2.5;Oligodendrocyte precursor cells: 2.8;Plasma cells: 1.7;Spermatocytes: 1.7;Spermatogonia: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.9;naive B-cell: 1.8" "Lineage enriched" "Detected in single" 5 "B-cells: 2.9" "Group enriched" "Detected in some" 4 "lymphoma: 9.8;Rhabdoid: 2.9" "Testis - Early spermatids" "Region enriched" "Detected in some" 9 "pons and medulla: 11.3" "Region enriched" "Detected in single" 46 "spinal cord: 13.6" HPA026992 Uncertain "Secreted - unknown location" Hormone NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 39: Retina & Testis - Cilium" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 73: B-cells - B-cell function" "HPA026992: AB_1858703" "unprognostic (1.73e-2)" "unprognostic (4.38e-2)" "unprognostic (1.22e-1)" "unprognostic (3.41e-1)" "unprognostic (1.92e-1)" "unprognostic (2.17e-2)" "unprognostic (2.77e-2)" "unprognostic (2.14e-2)" "unprognostic (3.09e-1)" "unprognostic (2.63e-2)" "unprognostic (3.39e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (7.58e-2)" "unprognostic (2.08e-1)" "unprognostic (1.29e-1)" "unprognostic (3.10e-2)" UTY "KDM6AL, KDM6C" ENSG00000183878 "Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked" O14607 Y 13234577-13480673 "Enzymes, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 55.4;Excitatory neurons: 64.5;Inhibitory neurons: 62.4;Oligodendrocytes: 61.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000568, HPA001165" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli rim" "Intracellular and membrane" Enzyme NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 49: Non-specific - Transcription" Nucleoplasm "Nucleoli, Nucleoli rim" "HPA000568: AB_1858705, HPA001165: AB_1080541" "unprognostic (7.52e-2)" "unprognostic (6.60e-2)" "unprognostic (4.04e-6)" "unprognostic (6.47e-2)" "unprognostic (9.34e-2)" "unprognostic (2.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.53e-2)" "unprognostic (1.29e-1)" "unprognostic (1.41e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.46e-2)" UXS1 "FLJ23591, SDR6E1, UGD" ENSG00000115652 "UDP-glucuronate decarboxylase 1" Q8NBZ7 2 106093308-106194301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 111.5;Early spermatids: 110.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Alveolar cells type 1, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008825 Uncertain "Intracellular and membrane" Enzyme NA NA 24000 "Cluster 6: T-cells - T-cell receptor" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Platelets - Hemostasis" "HPA008825: AB_1858708" "unprognostic (4.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.63e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.45e-4)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.20e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.94e-4)" "unprognostic (3.95e-2)" "unprognostic (1.40e-2)" "unprognostic (8.46e-2)" "unprognostic (3.96e-2)" "unprognostic (6.18e-2)" "unprognostic (1.86e-2)" "unprognostic (5.32e-2)" VASH1 KIAA1036 ENSG00000071246 "Vasohibin 1" Q7L8A9 14 76761468-76783015 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 65.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 90.1;Early spermatids: 58.8;Late spermatids: 100.6;Microglial cells: 51.0;Rod photoreceptor cells: 108.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000653 Uncertain "Secreted to blood" Enzyme NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Retina - Visual perception" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 66: Photoreceptor cells - Visual perception" 1 "HPA000653: AB_1080551" "unprognostic (1.47e-1)" "unprognostic (9.13e-2)" "unprognostic (2.56e-2)" "unprognostic (7.29e-2)" "unprognostic (1.93e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-3)" "unprognostic (1.62e-1)" "unprognostic (9.23e-2)" "unprognostic (6.94e-2)" "prognostic favorable (6.56e-6)" "unprognostic (8.84e-2)" "unprognostic (6.44e-3)" "unprognostic (2.69e-1)" "unprognostic (1.92e-1)" "unprognostic (5.06e-2)" "unprognostic (1.73e-1)" VASH2 FLJ12505 ENSG00000143494 "Vasohibin 2" Q86V25 1 212950520-212992037 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.7" "Group enriched" "Detected in some" 8 "dendritic cells: 106.5;Early spermatids: 88.9;Late spermatids: 88.2" "Cancer enhanced" "Detected in many" "testis cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 17.7" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045820 Supported Cytosol "Secreted to blood" Enzyme NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Testis - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 28: Dendritic cells - Antigen presentation" Cytosol "HPA045820: " "unprognostic (2.22e-1)" "unprognostic (1.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.29e-2)" "unprognostic (1.28e-1)" "unprognostic (1.57e-2)" "unprognostic (1.25e-2)" "unprognostic (4.04e-2)" "unprognostic (2.59e-3)" "unprognostic (3.50e-2)" "unprognostic (2.45e-1)" "unprognostic (6.58e-2)" "unprognostic (1.84e-5)" "unprognostic (1.95e-3)" "unprognostic (2.74e-1)" "unprognostic (6.85e-2)" "unprognostic (6.81e-4)" VASN SLITL2 ENSG00000168140 Vasorin Q6EMK4 16 4371848-4383538 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 56.4;Fibroblasts: 80.9;Peritubular cells: 60.5;Secretory cells: 53.6;Sertoli cells: 65.3;Smooth muscle cells: 76.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011246, HPA016992" Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted - unknown location" "No annotated function" NA Yes 2000000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 42 Mitochondria "Nucleoplasm, Nucleoli" "HPA011246: AB_1858720, HPA016992: AB_2732418" "unprognostic (2.20e-1)" "unprognostic (2.75e-1)" "unprognostic (9.22e-2)" "prognostic unfavorable (6.24e-5)" "unprognostic (2.35e-3)" "unprognostic (8.91e-3)" "unprognostic (3.15e-3)" "unprognostic (5.92e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (1.81e-1)" "unprognostic (8.82e-3)" "unprognostic (4.23e-2)" "unprognostic (4.95e-3)" "unprognostic (5.27e-2)" VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 72.9;placenta: 71.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 953.3;Fibroblasts: 344.3;Glandular and luminal cells: 293.1;Kupffer cells: 545.7;Macrophages: 552.5;Oligodendrocyte precursor cells: 1543.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 89.0" "Group enriched" "Detected in many" 20 "dendritic cells: 89.0;monocytes: 240.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 189.1" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" "No annotated function" NA NA 12000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Monocytes - Innate immune response" 2 Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" VEGFA "VEGF, VEGF-A, VPF" ENSG00000112715 "Vascular endothelial growth factor A" P15692 6 43770184-43786487 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 241.3;granulocytes: 274.5;Langerhans cells: 272.3" "Cancer enhanced" "Detected in all" "renal cancer: 79.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005429, CAB039240, HPA069116, CAB069907" Supported "Secreted to blood" "Growth factor" NA NA 562000 57000 "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Monocytes - Innate immune response" 3 "CAB005429: AB_2212984, CAB039240: , CAB069907: AB_10001947, HPA069116: AB_2686089" "unprognostic (1.12e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (2.42e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (4.35e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (2.34e-5)" "unprognostic (5.10e-2)" "unprognostic (5.27e-3)" "unprognostic (2.30e-2)" "unprognostic (1.40e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (1.76e-5)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.73e-4)" VEGFB "VEGFL, VRF" ENSG00000173511 "Vascular endothelial growth factor B" P49765 11 64234584-64239264 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 191.8;dendritic cells: 201.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 30.5" "Lineage enriched" "Detected in many" 10 "dendritic cells: 30.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" "Growth factor" NA NA 186000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 30: Heart muscle - Heart development" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Non-specific - DNA binding" 1 "unprognostic (4.88e-2)" "unprognostic (6.04e-2)" "unprognostic (1.33e-2)" "unprognostic (3.55e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.45e-1)" "unprognostic (4.68e-1)" "unprognostic (5.01e-3)" "unprognostic (2.35e-3)" "unprognostic (1.08e-2)" "unprognostic (1.67e-2)" "unprognostic (8.08e-3)" "unprognostic (2.00e-1)" "unprognostic (4.15e-2)" "unprognostic (4.31e-3)" VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 34.3;Endothelial cells: 22.6;Leydig cells: 14.2;Mesothelial cells: 17.5;Microglial cells: 34.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Prostate - Endothelial cells, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" "Growth factor" NA NA 383000 340000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" VEGFD "FIGF, VEGF-D" ENSG00000165197 "Vascular endothelial growth factor D" O43915 X 15345596-15384413 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 41.4" "Cell type enriched" "Detected in some" 8 "Fibroblasts: 65.4" "Cancer enhanced" "Detected in some" "liver cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 7.8" "Stomach - Fibroblasts" "Group enriched" "Detected in many" 4 "amygdala: 2.1;cerebral cortex: 3.5;hippocampal formation: 3.3;white matter: 2.6" "Low region specificity" "Detected in single" HPA027342 Uncertain "Secreted to blood" "Growth factor" NA NA 592000 450000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 53: Fibroblasts - ECM organization" 1 "HPA027342: AB_1848597" "unprognostic (5.90e-2)" "unprognostic (9.79e-3)" "unprognostic (1.02e-1)" "unprognostic (1.06e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-1)" "unprognostic (6.06e-3)" "unprognostic (5.57e-2)" "unprognostic (2.24e-3)" "unprognostic (2.65e-2)" "unprognostic (1.59e-5)" "unprognostic (3.08e-2)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.70e-1)" "unprognostic (3.85e-1)" "unprognostic (1.75e-2)" VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165569 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 75.2;pituitary gland: 51.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 24.6;Enteroendocrine cells: 54.9;Horizontal cells: 89.4;Inhibitory neurons: 35.9;Pancreatic endocrine cells: 161.3" "Cancer enriched" "Detected in many" 6 "melanoma: 236.3" "Region enriched" "Detected in all" 6 "hypothalamus: 2693.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 141.0;skin cancer: 234.3" "Colon - Colon enteroendocrine cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055177, HPA072505" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" "Growth factor" NA NA 1270000 3100000 "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Golgi apparatus, Vesicles" "HPA055177: AB_2682728, HPA072505: AB_2686528" "unprognostic (3.04e-2)" "unprognostic (3.45e-1)" "unprognostic (3.19e-3)" "prognostic unfavorable (4.25e-4)" "prognostic unfavorable (3.31e-4)" "unprognostic (1.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.66e-3)" "unprognostic (2.25e-2)" "unprognostic (8.77e-2)" "unprognostic (3.84e-3)" "unprognostic (3.70e-3)" "unprognostic (9.82e-3)" "unprognostic (3.79e-1)" "unprognostic (7.23e-2)" "unprognostic (4.36e-3)" "unprognostic (2.21e-1)" VIP ENSG00000146469 "Vasoactive intestinal peptide" P01282 6 152750797-152759765 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 69.7;lymphoid tissue: 151.2" "Group enriched" "Detected in some" 6 "Inhibitory neurons: 76.7;Melanocytes: 27.5" "Group enriched" "Detected in some" 6 "colorectal cancer: 3.7;pancreatic cancer: 4.3;stomach cancer: 2.6" "Group enriched" "Detected in many" 4 "hypothalamus: 51.9;midbrain: 78.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 131.7" "Colon - Colon enteroendocrine cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA017324, CAB018649, HPA072701, CAB079780" Supported Supported Approved "Endoplasmic reticulum" "Secreted to blood" Hormone NA NA 122000 "Cluster 45: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 70: DU4475 - Unknown function" "Cluster 69: Neurons - Neuronal signaling" 1 "Endoplasmic reticulum" "CAB018649: AB_2304501, CAB079780: , HPA017324: AB_1858754, HPA072701: AB_2686550" "unprognostic (9.58e-2)" "unprognostic (2.29e-2)" "unprognostic (2.60e-2)" "unprognostic (1.13e-1)" "unprognostic (3.34e-2)" "unprognostic (3.33e-2)" "unprognostic (2.48e-2)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (3.62e-1)" "unprognostic (2.92e-3)" "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (1.30e-1)" "unprognostic (5.90e-2)" VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814794 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 34.3;ovary: 36.6;tongue: 39.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 27.9;Fibroblasts: 84.3;Leydig cells: 116.4;Ovarian stromal cells: 23.8;Peritubular cells: 23.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cancer enriched" "Detected in many" 5 "testis cancer: 57.3" "Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" Other NA NA 140000 "Cluster 24: Non-specific - Transcription" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 53: Fibroblasts - ECM organization" "unprognostic (5.34e-4)" "unprognostic (4.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.20e-1)" "unprognostic (7.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.08e-1)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (3.66e-6)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (1.41e-2)" VKORC1 VKCFD2 ENSG00000167397 "Vitamin K epoxide reductase complex subunit 1" Q9BQB6 16 31090842-31095980 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 443.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 767.1;Oocytes: 587.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042720 Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Hepatocytes - Metabolism" 12 "Endoplasmic reticulum" "HPA042720: AB_10961864" "unprognostic (5.99e-2)" "unprognostic (2.98e-1)" "unprognostic (7.11e-3)" "unprognostic (7.68e-3)" "unprognostic (5.49e-2)" "unprognostic (3.23e-3)" "unprognostic (3.02e-2)" "unprognostic (2.32e-2)" "unprognostic (2.42e-1)" "unprognostic (2.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.09e-10)" "unprognostic (1.11e-2)" "unprognostic (6.65e-2)" "unprognostic (3.12e-2)" "unprognostic (9.66e-2)" VMO1 ENSG00000182853 "Vitelline membrane outer layer 1 homolog" Q7Z5L0 17 4785285-4786433 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.3;pituitary gland: 26.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 292.7;Club cells: 656.5;Ionocytes: 1133.2;Langerhans cells: 217.9;monocytes: 384.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "non-classical monocyte: 112.2" "Lineage enriched" "Detected in many" 9 "monocytes: 112.2" "Cancer enhanced" "Detected in many" "Bone cancer: 4.9" "Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA023038 Uncertain "Secreted to blood" "No annotated function" NA NA 2900000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA023038: AB_10964632" "unprognostic (1.30e-1)" "unprognostic (5.71e-2)" "unprognostic (1.65e-3)" "unprognostic (9.09e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (5.58e-3)" "unprognostic (1.20e-1)" "unprognostic (1.65e-1)" "unprognostic (7.41e-2)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.34e-6)" "unprognostic (1.10e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-1)" "unprognostic (2.69e-1)" VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132680849-132714055 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "gallbladder: 86.2;intestine: 132.5;liver: 212.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 55.3;Ductal cells: 259.1;Exocrine glandular cells: 71.0;Hepatocytes: 67.5;monocytes: 181.9;Proximal enterocytes: 52.0" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 13.7;non-classical monocyte: 12.0" "Group enriched" "Detected in many" 80 "dendritic cells: 5.0;granulocytes: 8.5;monocytes: 13.7" "Cancer enhanced" "Detected in many" "liver cancer: 13.2;thyroid cancer: 9.6" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Kidney - Proximal tubular cells, Lung - Neutrophil_2" "Region enhanced" "Detected in single" "white matter: 2.4" "Not detected" "Not detected" "HPA046103, HPA064145" Approved Approved Vesicles "Intracellular and membrane" Enzyme NA NA 980000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA046103: , HPA064145: AB_2685197" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" VPREB1 "CD179A, VpreB" ENSG00000169575 "V-set pre-B cell surrogate light chain 1" P12018 22 22244780-22245515 "CD markers, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "bone marrow: 29.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 5.7;naive B-cell: 5.3" "Lineage enriched" "Detected in many" 5 "B-cells: 5.7" "Cancer enriched" "Detected in some" 4 "Leukemia: 204.5" "Breast - Plasma cells, Lung - Plasma cells, Stomach - Plasma cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA055886 Approved "Intracellular and membrane" "No annotated function" NA NA 62000 "Cluster 34: B-cells - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 19: NK-cells - Adaptive immune response" "HPA055886: AB_2682956" VPREB3 8HS20 ENSG00000128218 "V-set pre-B cell surrogate light chain 3" Q9UKI3 22 23752743-23754425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 50.2;intestine: 70.5;lymphoid tissue: 115.0" "Cell type enriched" "Detected in some" 16 "B-cells: 279.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 707 "memory B-cell: 756.8;naive B-cell: 807.5" "Lineage enriched" "Detected in many" 730 "B-cells: 807.5" "Group enriched" "Detected in some" 34 "Leukemia: 127.1;lymphoma: 273.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA003041 Supported "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 73: B-cells - B-cell function" "HPA003041: AB_1080577" "unprognostic (2.06e-3)" "unprognostic (4.75e-3)" "unprognostic (2.35e-1)" "unprognostic (2.39e-2)" "unprognostic (1.21e-2)" "unprognostic (2.75e-2)" "unprognostic (4.79e-2)" "unprognostic (6.63e-3)" "unprognostic (9.15e-2)" "unprognostic (1.38e-2)" "unprognostic (4.93e-2)" "unprognostic (4.84e-2)" "unprognostic (8.44e-2)" "unprognostic (4.19e-2)" "unprognostic (1.18e-1)" "unprognostic (2.87e-1)" "unprognostic (4.12e-1)" VSTM1 UNQ3033 ENSG00000189068 "V-set and transmembrane domain containing 1" Q6UX27 19 54040825-54063953 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 42.5" "Group enriched" "Detected in some" 4 "Hofbauer cells: 16.9;Late spermatids: 19.9;monocytes: 27.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 16 "eosinophil: 129.6" "Lineage enriched" "Detected in many" 16 "granulocytes: 129.6" "Cancer enhanced" "Detected in single" "Leukemia: 1.2" "Low region specificity" "Detected in all" HPA059365 Approved Vesicles "Secreted to blood" Cytokine NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Vesicles "HPA059365: " "unprognostic (5.13e-2)" "unprognostic (5.31e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (3.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (9.47e-2)" "unprognostic (1.31e-5)" "unprognostic (3.73e-1)" "unprognostic (1.14e-1)" "unprognostic (9.74e-2)" "unprognostic (4.67e-2)" VSTM2A "MGC33530, VSTM2" ENSG00000170419 "V-set and transmembrane domain containing 2A" Q8TAG5 7 54542325-54571080 "Plasma proteins, Predicted secreted proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.9;brain: 33.2;prostate: 9.4;retina: 13.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 36.8;Excitatory neurons: 12.1;Fibroblasts: 7.0;Horizontal cells: 17.6;Inhibitory neurons: 28.8" "Cancer enhanced" "Detected in some" "breast cancer: 4.6;glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 7.7;prostate cancer: 4.5;thyroid cancer: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" Other NA NA 31000 "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" "unprognostic (1.15e-1)" "unprognostic (1.02e-1)" "unprognostic (1.89e-1)" "unprognostic (1.14e-2)" "unprognostic (4.66e-1)" "prognostic favorable (5.34e-4)" "unprognostic (4.34e-2)" "unprognostic (6.79e-2)" "unprognostic (7.15e-2)" VSTM2L "C20orf102, dJ1118M15.2" ENSG00000132821 "V-set and transmembrane domain containing 2 like" Q96N03 20 37903111-37945350 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 99.3;heart muscle: 79.1;lymphoid tissue: 28.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 26.6;Cholangiocytes: 72.5;Ciliated cells: 66.3;Club cells: 33.1;Horizontal cells: 29.0;Inhibitory neurons: 42.1" "Group enriched" "Detected in all" 5 "lung cancer: 23.6;pancreatic cancer: 34.4;prostate cancer: 72.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043832 Uncertain "Secreted - unknown location" "No annotated function" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Ciliated cells - Cilium assembly" 2 "HPA043832: AB_10968449" "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.33e-2)" "prognostic unfavorable (1.63e-5)" "unprognostic (4.96e-3)" "unprognostic (1.56e-1)" "unprognostic (1.83e-2)" "unprognostic (1.39e-1)" "unprognostic (1.52e-1)" "unprognostic (2.34e-3)" "unprognostic (9.86e-2)" "unprognostic (2.00e-1)" "unprognostic (1.85e-3)" "unprognostic (1.29e-3)" "unprognostic (1.68e-1)" "unprognostic (9.66e-2)" "prognostic unfavorable (8.14e-4)" VSTM4 "C10orf72, FLJ31737" ENSG00000165633 "V-set and transmembrane domain containing 4" Q8IW00 10 49014236-49115522 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 66.3;Granulosa cells: 66.1;Late spermatids: 150.8;Ovarian stromal cells: 39.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 22.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 8.2" "Breast - Adipocytes (Breast), Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017279 Uncertain Approved Nucleoplasm,Vesicles "Secreted - unknown location" "No annotated function" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Late spermatids - Unknown function" 8 "Nucleoplasm, Vesicles" "HPA017279: AB_10959519" "unprognostic (8.46e-2)" "unprognostic (5.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (1.80e-1)" "unprognostic (2.84e-2)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.25e-4)" VTN VN ENSG00000109072 Vitronectin P04004 17 28367284-28373091 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins, Transporters" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 5852.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 4354.3" "Cancer enriched" "Detected in many" 85 "liver cancer: 2216.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 132.3" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB016695, CAB016765, HPA060933, HPA068011" Supported Supported "Endoplasmic reticulum,Vesicles" "Secreted to blood" "Cell adhesion" NA NA 606000000000 33000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 7 "Endoplasmic reticulum, Vesicles" "CAB016695: AB_1624536, CAB016765: , HPA060933: AB_2684389, HPA068011: " "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.29e-2)" "unprognostic (6.13e-2)" "unprognostic (9.74e-2)" "unprognostic (8.42e-2)" "prognostic favorable (3.74e-4)" "unprognostic (6.20e-2)" "unprognostic (3.97e-1)" "unprognostic (8.95e-2)" "unprognostic (3.24e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.10e-11)" "unprognostic (8.82e-3)" "unprognostic (2.27e-1)" "unprognostic (4.86e-3)" "unprognostic (7.09e-2)" VWA1 "FLJ22215, VWA-1, WARP" ENSG00000179403 "Von Willebrand factor A domain containing 1" Q6PCB0 1 1434861-1442882 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 196.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 261.8;Schwann cells: 368.1;Syncytiotrophoblasts: 258.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 115.4" "Kidney - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "No annotated function" NA NA 250000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 24: Cytotrophoblasts - Mitochondria" "unprognostic (2.78e-1)" "unprognostic (4.85e-2)" "unprognostic (5.91e-3)" "unprognostic (2.75e-1)" "unprognostic (2.67e-3)" "unprognostic (6.73e-2)" "unprognostic (9.52e-3)" "unprognostic (8.11e-2)" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (3.47e-1)" "unprognostic (2.79e-2)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-2)" "unprognostic (3.08e-2)" "unprognostic (6.71e-2)" VWA2 "AMACO, CCSP-2, FLJ16213, FLJ45857, NET42" ENSG00000165816 "Von Willebrand factor A domain containing 2" Q5GFL6 10 114239254-114294489 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 8.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 12.4;Ionocytes: 12.9;Late spermatids: 16.2;Microglial cells: 16.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.1;Gastric cancer: 6.4" "Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037847 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "HPA037847: AB_10670961" "unprognostic (6.03e-2)" "unprognostic (8.29e-2)" "unprognostic (3.27e-2)" "unprognostic (7.33e-2)" "unprognostic (1.26e-2)" "unprognostic (6.82e-2)" "unprognostic (3.02e-2)" "unprognostic (9.33e-3)" "unprognostic (2.44e-1)" "unprognostic (3.70e-1)" "unprognostic (1.37e-3)" "unprognostic (3.14e-1)" "unprognostic (7.27e-3)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (9.30e-2)" "unprognostic (1.22e-1)" VWA3A "FLJ40941, FLJ46765" ENSG00000175267 "Von Willebrand factor A domain containing 3A" A6NCI4 16 22092538-22156964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 55.4;fallopian tube: 38.5" "Cell type enhanced" "Detected in some" "Astrocytes: 24.2;Ciliated cells: 56.5;Early spermatids: 14.4;Excitatory neurons: 32.6;Late spermatids: 13.3" "Group enriched" "Detected in some" 4 "endometrial cancer: 3.2;glioma: 1.4;ovarian cancer: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Bile duct cancer: 2.5" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041696, HPA042044" Uncertain "Secreted in other tissues" "No annotated function" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" "HPA041696: AB_10964202, HPA042044: AB_10968997" "unprognostic (2.69e-2)" "unprognostic (1.54e-1)" "unprognostic (9.75e-4)" "prognostic favorable (8.15e-4)" "unprognostic (2.70e-1)" "unprognostic (4.46e-2)" "unprognostic (1.65e-2)" "unprognostic (6.79e-3)" "unprognostic (5.55e-2)" "unprognostic (2.67e-1)" "unprognostic (6.81e-2)" "unprognostic (1.40e-1)" "unprognostic (2.16e-5)" "unprognostic (1.08e-1)" "unprognostic (2.97e-1)" "unprognostic (6.24e-2)" "unprognostic (3.06e-4)" VWA5B1 FLJ32784 ENSG00000158816 "Von Willebrand factor A domain containing 5B1" Q5TIE3 1 20290875-20359518 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "choroid plexus: 13.6" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Early spermatids: 12.0;granulocytes: 1.6;Inhibitory neurons: 1.7;Late spermatids: 7.5" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "choroid plexus: 47.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Lung - Fibroblast_1, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA027496, HPA028405, HPA064829" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 18: Early spermatids - Unknown function" Mitochondria "Plasma membrane, Cytosol" "HPA027496: AB_10599853, HPA028405: AB_10600992, HPA064829: AB_2685363" "unprognostic (2.34e-1)" "unprognostic (2.91e-1)" "unprognostic (7.78e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.86e-2)" "unprognostic (4.39e-2)" "unprognostic (1.73e-1)" "unprognostic (5.41e-4)" "unprognostic (7.43e-4)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" VWA7 "C6orf27, G7c, NG37" ENSG00000204396 "Von Willebrand factor A domain containing 7" Q9Y334 6 31765590-31777328 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 20.7" "Cell type enhanced" "Detected in some" "Ciliated cells: 3.9;Distal enterocytes: 2.2;Gastric mucus-secreting cells: 7.7;Proximal enterocytes: 4.8;Proximal tubular cells: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Group enriched" "Detected in some" 5 "cerebellum: 7.0;pons and medulla: 3.9" "Low region specificity" "Detected in many" "HPA046954, HPA054262" Approved Approved "Plasma membrane,Cytosol" "Secreted - unknown location" "No annotated function" NA NA 9200 "Cluster 66: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA046954: AB_2679875, HPA054262: AB_2682430" "unprognostic (9.13e-2)" "unprognostic (8.60e-4)" "unprognostic (9.99e-2)" "unprognostic (2.43e-1)" "unprognostic (2.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.38e-2)" "unprognostic (4.40e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-2)" "unprognostic (1.65e-2)" "unprognostic (9.25e-2)" "prognostic favorable (4.35e-8)" "unprognostic (3.75e-2)" "unprognostic (2.37e-1)" "unprognostic (9.48e-2)" "unprognostic (7.66e-2)" VWC2 "PSST739, UNQ739" ENSG00000188730 "Von Willebrand factor C domain containing 2" Q2TAL6 7 49773638-49921950 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.7;heart muscle: 4.8;ovary: 3.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 50.1;Excitatory neurons: 63.0;Granulosa cells: 42.9;Inhibitory neurons: 347.4;Oligodendrocyte precursor cells: 153.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055243 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 39000 "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Neurons - Neuronal signaling" 51 "HPA055243: AB_2682755" "unprognostic (3.30e-1)" "unprognostic (1.04e-1)" "unprognostic (8.90e-4)" "unprognostic (8.97e-2)" "unprognostic (8.77e-2)" "unprognostic (1.56e-3)" "unprognostic (3.41e-2)" "unprognostic (4.11e-1)" "unprognostic (6.65e-2)" "unprognostic (1.69e-4)" "unprognostic (1.60e-2)" "unprognostic (2.09e-2)" "unprognostic (1.52e-1)" "unprognostic (1.94e-1)" "unprognostic (9.70e-3)" VWC2L ENSG00000174453 "Von Willebrand factor C domain containing 2 like" B2RUY7 2 214411054-214578976 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 2.5;retina: 1.4" "Group enriched" "Detected in some" 21 "Excitatory neurons: 64.6;Inhibitory neurons: 127.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044815, HPA059414" Uncertain "Secreted - unknown location" "Developmental protein" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" 20 "HPA044815: AB_10962359, HPA059414: AB_2684007" "unprognostic (8.77e-2)" "unprognostic (2.83e-3)" "unprognostic (2.05e-2)" "unprognostic (8.49e-2)" "unprognostic (1.51e-3)" "unprognostic (4.36e-1)" "unprognostic (2.56e-2)" "unprognostic (2.05e-1)" "unprognostic (3.89e-1)" VWCE "FLJ32009, URG11, VWC1" ENSG00000167992 "Von Willebrand factor C and EGF domains" Q96DN2 11 61258286-61295316 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 13.9;ovary: 7.7" "Cell type enhanced" "Detected in many" "Astrocytes: 18.3;Cone photoreceptor cells: 10.2;Hepatocytes: 13.6;Rod photoreceptor cells: 22.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 6.1" "Colon - Endothelial cells, Lung - Fibroblast_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040401, HPA043921" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" "No annotated function" NA NA 2200000 "Cluster 83: Liver - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 66: Photoreceptor cells - Visual perception" 3 Nucleoplasm "Vesicles, Cytosol" "HPA040401: AB_2676963, HPA043921: AB_2678731" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (3.58e-2)" "unprognostic (1.15e-1)" "unprognostic (3.96e-3)" "unprognostic (9.27e-4)" "unprognostic (1.21e-2)" "unprognostic (4.01e-4)" "unprognostic (3.04e-2)" "unprognostic (3.42e-2)" "unprognostic (6.58e-4)" "unprognostic (7.20e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-1)" VWDE FLJ14712 ENSG00000146530 "Von Willebrand factor D and EGF domains" Q8N2E2 7 12330885-12403941 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 4.0;salivary gland: 2.9;thyroid gland: 3.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.7;Excitatory neurons: 11.4;Inhibitory neurons: 11.0;Serous glandular cells: 7.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 11.6" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "HPA026619, HPA036044, HPA036045" Uncertain Approved Cytosol "Secreted - unknown location" "No annotated function" NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" Cytosol "HPA026619: AB_2671920, HPA036044: AB_2674916, HPA036045: " "unprognostic (6.39e-2)" "unprognostic (1.65e-3)" "unprognostic (5.36e-3)" "unprognostic (1.78e-4)" "unprognostic (1.39e-2)" "unprognostic (4.19e-3)" "unprognostic (2.38e-1)" "unprognostic (1.85e-1)" "unprognostic (1.78e-1)" "unprognostic (6.25e-2)" "unprognostic (1.68e-1)" "unprognostic (6.72e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-3)" "unprognostic (1.58e-1)" "unprognostic (1.10e-1)" "unprognostic (2.73e-1)" VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 917.4;Endothelial cells: 827.6" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" "Blood coagulation" NA NA 28300000000 5600000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" WDR25 "C14orf67, MGC4645" ENSG00000176473 "WD repeat domain 25" Q64LD2 14 100376418-100530303 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003113 Uncertain Approved Nucleoplasm "Secreted to blood" "No annotated function" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 65: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 5 Nucleoplasm "HPA003113: AB_2215263" "unprognostic (5.31e-2)" "unprognostic (5.76e-3)" "unprognostic (2.28e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.36e-4)" "unprognostic (1.79e-2)" "unprognostic (6.62e-2)" "unprognostic (3.94e-3)" "unprognostic (2.44e-2)" "unprognostic (1.37e-2)" "prognostic favorable (3.89e-5)" "unprognostic (1.01e-2)" "unprognostic (1.73e-1)" "unprognostic (7.30e-2)" "unprognostic (7.51e-2)" WDR81 "CAMRQ2, FLJ33817, PPP1R166, SORF-2" ENSG00000167716 "WD repeat domain 81" Q562E7 17 1716523-1738599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023044, HPA063703" Uncertain Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 58: Macrophages - Innate immune response" 1 Nucleoplasm "Vesicles, Cytosol" "HPA023044: AB_1858822, HPA063703: " "unprognostic (1.00e-1)" "unprognostic (4.67e-2)" "unprognostic (6.63e-2)" "unprognostic (4.90e-3)" "unprognostic (6.10e-2)" "unprognostic (7.75e-3)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (3.06e-2)" "unprognostic (1.60e-2)" "prognostic favorable (3.30e-4)" "unprognostic (3.26e-1)" "unprognostic (8.72e-2)" "unprognostic (2.25e-1)" "unprognostic (8.43e-2)" "unprognostic (7.99e-2)" "unprognostic (3.90e-2)" WFDC1 PS20 ENSG00000103175 "WAP four-disulfide core domain 1" Q9HC57 16 84294846-84329844 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 96.4;seminal vesicle: 111.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 91.4;Late spermatids: 43.6;Peritubular cells: 256.5;Smooth muscle cells: 108.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "skin cancer: 74.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031411 Uncertain "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "HPA031411: AB_10600921" "unprognostic (6.53e-2)" "unprognostic (1.27e-1)" "unprognostic (1.61e-2)" "unprognostic (8.66e-4)" "unprognostic (1.41e-2)" "unprognostic (1.50e-3)" "unprognostic (1.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.60e-1)" "unprognostic (2.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (3.78e-2)" "unprognostic (5.49e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (3.04e-1)" WFDC10A "C20orf146, dJ688G8.3, WAP10" ENSG00000180305 "WAP four-disulfide core domain 10A" Q9H1F0 20 45629739-45631196 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 444 "epididymis: 280.5" "Cell type enhanced" "Detected in some" "Early spermatids: 1.0;Late spermatids: 1.8;Oocytes: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected" "Not detected" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Late spermatids - Unknown function" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" WFDC10B WAP12 ENSG00000182931 "WAP four-disulfide core domain 10B" Q8IUB3 20 45684651-45705019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 26.5;retina: 11.1" "Cell type enhanced" "Detected in some" "Astrocytes: 3.4;Cone photoreceptor cells: 3.4;Early spermatids: 5.1;Late spermatids: 10.4;Microglial cells: 3.6;Rod photoreceptor cells: 8.2;Spermatocytes: 3.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Eccrine sweat gland cells" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" 1 "unprognostic (1.14e-1)" "unprognostic (2.31e-1)" "unprognostic (1.37e-4)" "unprognostic (1.60e-1)" "unprognostic (2.69e-1)" "unprognostic (4.81e-2)" "unprognostic (4.30e-3)" "unprognostic (5.64e-2)" "unprognostic (1.14e-2)" "unprognostic (3.36e-1)" "unprognostic (0.00e+0)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" "unprognostic (2.21e-2)" "unprognostic (3.17e-1)" WFDC11 WAP11 ENSG00000180083 "WAP four-disulfide core domain 11" Q8NEX6 20 45648563-45670270 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 19 "epididymis: 91.7" "Group enriched" "Detected in some" 27 "Early spermatids: 39.2;Late spermatids: 22.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 2.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.3" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" WFDC12 "C20orf122, dJ211D12.4, WAP2" ENSG00000168703 "WAP four-disulfide core domain 12" Q8WWY7 20 45123425-45124465 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 40.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.5;Alveolar cells type 2: 8.7;Basal prostatic cells: 1.7;Collecting duct cells: 3.9;Ionocytes: 1.5;Suprabasal keratinocytes: 2.4" "Group enriched" "Detected in many" 7 "head and neck cancer: 18.9;melanoma: 14.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 3.5" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Secreted in other tissues" "Enzyme inhibitor" NA NA 86000 "Cluster 13: Skin - Cornification" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 5 "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "unprognostic (1.18e-2)" "unprognostic (5.42e-2)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (3.40e-3)" "unprognostic (1.72e-2)" "unprognostic (8.70e-3)" "prognostic unfavorable (5.65e-4)" "unprognostic (4.49e-2)" "unprognostic (3.91e-1)" "unprognostic (5.50e-3)" WFDC13 "C20orf138, dJ601O1.3, WAP13" ENSG00000168634 "WAP four-disulfide core domain 13" Q8IUB5 20 45702038-45708817 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "epididymis: 87.3" "Cell type enhanced" "Detected in some" "Oocytes: 2.2;Rod photoreceptor cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 66: Photoreceptor cells - Visual perception" 1 "unprognostic (2.53e-1)" "unprognostic (1.30e-2)" "unprognostic (7.84e-3)" "unprognostic (7.96e-3)" "unprognostic (2.04e-1)" "unprognostic (1.02e-11)" "unprognostic (1.17e-1)" "unprognostic (1.44e-2)" "unprognostic (2.22e-2)" WFDC2 "dJ461P17.6, EDDM4, HE4, WAP5" ENSG00000101443 "WAP four-disulfide core domain 2" Q14508 20 45469753-45481532 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Aspartic protease inhibitor, Protease inhibitor, Serine protease inhibitor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 5022.3;salivary gland: 1926.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 4980.5;Ciliated cells: 2976.8;Club cells: 6611.7;Glandular and luminal cells: 5185.3;Ionocytes: 5925.0;Mucus glandular cells: 4025.9;Salivary duct cells: 7309.6;Secretory cells: 3901.4;Serous glandular cells: 2849.6" "Group enriched" "Detected in all" 4 "endometrial cancer: 1815.6;ovarian cancer: 1086.5" "Region enhanced" "Detected in all" "choroid plexus: 36.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 312.2;pancreatic cancer: 279.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042302 Enhanced "Secreted in other tissues" "Enzyme inhibitor" NA NA 1600000 "Cluster 64: Neuronal - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" 14 "HPA042302: AB_2677939" "unprognostic (5.75e-2)" "unprognostic (2.23e-1)" "unprognostic (4.37e-2)" "unprognostic (2.99e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (7.19e-3)" "unprognostic (1.94e-1)" "unprognostic (5.49e-3)" "unprognostic (3.71e-1)" "unprognostic (2.01e-1)" "unprognostic (1.42e-1)" "unprognostic (1.40e-1)" "prognostic favorable (4.44e-5)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-1)" "unprognostic (3.20e-2)" WFDC3 "dJ447F3.3, WAP14" ENSG00000124116 "WAP four-disulfide core domain 3" Q8IUB2 20 45747944-45791932 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 16.2;testis: 19.4" "Group enriched" "Detected in many" 6 "Early spermatids: 131.9;Late spermatids: 221.8;Spermatocytes: 89.5" "Cancer enhanced" "Detected in many" "lung cancer: 2.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 21: Testis - Unknown function" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Late spermatids - Spermatogenesis" 2 "unprognostic (7.47e-2)" "unprognostic (1.94e-1)" "unprognostic (2.64e-1)" "unprognostic (2.39e-2)" "unprognostic (1.06e-1)" "unprognostic (5.75e-2)" "unprognostic (9.30e-4)" "unprognostic (6.63e-3)" "unprognostic (4.02e-2)" "unprognostic (1.47e-1)" "unprognostic (1.69e-3)" "unprognostic (1.79e-1)" "unprognostic (1.36e-8)" "unprognostic (8.53e-2)" "unprognostic (2.45e-1)" "unprognostic (5.27e-3)" "unprognostic (3.03e-2)" WFDC5 "dJ211D12.5, WAP1" ENSG00000175121 "WAP four-disulfide core domain 5" Q8TCV5 20 45109452-45115174 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "skin 1: 387.8" "Group enriched" "Detected in some" 8 "Basal keratinocytes: 39.0;Early spermatids: 11.5;Late spermatids: 14.9;Suprabasal keratinocytes: 33.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 1.6;head and neck cancer: 5.0" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Enzyme inhibitor" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 4 "unprognostic (1.32e-1)" "unprognostic (3.22e-2)" "unprognostic (3.05e-1)" "unprognostic (1.54e-1)" "unprognostic (1.28e-4)" "unprognostic (6.59e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (2.32e-5)" "unprognostic (4.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.96e-2)" WFDC6 "C20orf171, dJ461P17.11, WAP6" ENSG00000243543 "WAP four-disulfide core domain 6" Q9BQY6 20 45534196-45539482 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "epididymis: 217.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.9;testis cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Kidney cancer - Membrane components" "unprognostic (3.68e-3)" "unprognostic (2.21e-3)" "unprognostic (1.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.91e-2)" WFDC8 "C20orf170, dJ461P17.1, WAP8" ENSG00000158901 "WAP four-disulfide core domain 8" Q8IUA0 20 45551153-45579326 "Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 523 "epididymis: 400.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042710, HPA071119" Enhanced "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA042710: AB_2732501, HPA071119: AB_2732172" "unprognostic (5.63e-3)" "unprognostic (1.09e-2)" "unprognostic (2.34e-1)" "unprognostic (9.96e-2)" "unprognostic (1.07e-2)" WFDC9 "dJ688G8.2, WAP9" ENSG00000180205 "WAP four-disulfide core domain 9" Q8NEX5 20 45607939-45631284 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 459 "epididymis: 964.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 63: Late spermatids - Spermatogenesis" 1 WFIKKN1 "C16orf12, RJD2, WFDC20A, WFIKKN" ENSG00000127578 "WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1" Q96NZ8 16 629239-634117 "Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;kidney: 2.3" "Cell type enhanced" "Detected in many" "Astrocytes: 4.6;Horizontal cells: 5.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted in other tissues" "Enzyme inhibitor" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 55: Non-specific - Transcription" 2 "unprognostic (3.12e-1)" "unprognostic (2.57e-1)" "unprognostic (3.17e-2)" "unprognostic (1.59e-2)" "unprognostic (3.55e-1)" "unprognostic (2.28e-2)" "unprognostic (3.36e-2)" "unprognostic (4.45e-2)" "unprognostic (8.53e-2)" "unprognostic (2.43e-1)" "unprognostic (3.78e-3)" "unprognostic (1.19e-1)" "unprognostic (5.56e-3)" "unprognostic (1.53e-1)" "unprognostic (3.02e-1)" "unprognostic (2.50e-3)" "unprognostic (4.70e-5)" WFIKKN2 "WFDC20B, WFIKKNRP" ENSG00000173714 "WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2" Q8TEU8 17 50834650-50842353 "Predicted intracellular proteins, Predicted secreted proteins" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "choroid plexus: 1135.6" "Cell type enhanced" "Detected in some" "Granulosa cells: 4.3;Leydig cells: 9.1;Oocytes: 11.8;Ovarian stromal cells: 21.3;Peritubular cells: 24.3;Sertoli cells: 5.4" "Group enriched" "Detected in some" 5 "glioma: 0.7;testis cancer: 2.2" "Region enriched" "Detected in all" 71 "choroid plexus: 1253.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Brain cancer: 3.0;Neuroblastoma: 4.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "medulla oblongata: 15.1;midbrain: 6.2;thalamus: 7.4" "Secreted in other tissues" "Enzyme inhibitor" NA NA 4500000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 6: Ovarian stromal cells - Transcription" "unprognostic (7.31e-2)" "unprognostic (7.31e-2)" "unprognostic (1.31e-2)" "unprognostic (4.80e-2)" "unprognostic (3.46e-2)" "unprognostic (5.72e-2)" "unprognostic (5.42e-3)" "unprognostic (2.54e-3)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (2.19e-1)" "unprognostic (4.08e-3)" "unprognostic (1.42e-3)" "unprognostic (2.17e-1)" "unprognostic (2.75e-2)" "unprognostic (1.14e-1)" WIF1 ENSG00000156076 "WNT inhibitory factor 1" Q9Y5W5 12 65050626-65121305 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 581.3" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 2302.6" "Group enriched" "Detected in many" 5 "endometrial cancer: 16.9;lung cancer: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Rhabdoid: 16.6;Uterine cancer: 22.3" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Skin - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 76: Retina - Visual perception" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 32: Non-specific - Cell proliferation" "Cluster 10: Muller glia cells - Visual perception" 4 "unprognostic (5.96e-3)" "unprognostic (2.00e-1)" "unprognostic (4.29e-3)" "unprognostic (3.26e-3)" "unprognostic (9.66e-2)" "unprognostic (1.91e-1)" "unprognostic (1.26e-2)" "unprognostic (7.94e-2)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (3.17e-1)" "unprognostic (2.30e-5)" "unprognostic (3.02e-1)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (7.24e-3)" WNT1 INT1 ENSG00000125084 "Wnt family member 1" P04628 12 48978322-48982620 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Osteogenesis imperfecta, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.8" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 4.4;Langerhans cells: 2.3;NK-cells: 2.9;Spermatocytes: 4.9;Spermatogonia: 3.5;T-cells: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "gdT-cell: 3.1;MAIT T-cell: 5.1;memory CD4 T-cell: 2.0;memory CD8 T-cell: 2.9;naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 32 "T-cells: 5.1" "Cancer enriched" "Detected in single" 26 "ovarian cancer: 10.0" "Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "unprognostic (2.02e-2)" "unprognostic (5.80e-3)" "unprognostic (1.23e-1)" "unprognostic (1.64e-2)" "unprognostic (1.03e-1)" "unprognostic (7.65e-3)" "unprognostic (5.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (4.08e-2)" "unprognostic (4.97e-2)" "unprognostic (1.32e-2)" "unprognostic (1.67e-2)" "unprognostic (1.70e-1)" "unprognostic (7.35e-3)" "unprognostic (2.76e-2)" WNT10A ENSG00000135925 "Wnt family member 10A" Q9GZT5 2 218880852-218899581 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant, Ectodermal dysplasia, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.8;skin 1: 8.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 18.8;Basal respiratory cells: 14.8;Basal squamous epithelial cells: 17.1;Collecting duct cells: 21.4;dendritic cells: 36.0;Plasma cells: 24.8;Secretory cells: 12.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 6.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 6.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 38.9" "Adipose visceral - Mesothelial cells, Stomach - Plasma cells, Testis - Early spermatids, Thyroid - T-cells" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Region enhanced" "Detected in some" "basal ganglia: 3.2" HPA013898 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 77: Plasma cells - Protein processing" "HPA013898: AB_1858847" "unprognostic (2.99e-4)" "unprognostic (4.31e-2)" "unprognostic (8.55e-2)" "unprognostic (1.17e-3)" "unprognostic (2.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-2)" "unprognostic (1.04e-1)" "unprognostic (6.34e-2)" "unprognostic (2.23e-3)" "unprognostic (9.52e-2)" "unprognostic (6.64e-9)" "unprognostic (1.22e-1)" "unprognostic (1.72e-1)" "unprognostic (4.89e-3)" "unprognostic (1.82e-1)" WNT10B "SHFM6, WNT-12" ENSG00000169884 "Wnt family member 10B" O00744 12 48965340-48971735 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 38.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.1;Extravillous trophoblasts: 26.5;Fibroblasts: 4.9;Inhibitory neurons: 4.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 18.6" "Kidney - T-cells, Prostate - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA055048 Enhanced "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "HPA055048: AB_2682683" "unprognostic (1.13e-1)" "unprognostic (2.14e-2)" "unprognostic (5.73e-4)" "unprognostic (2.27e-2)" "unprognostic (3.09e-2)" "unprognostic (3.33e-2)" "unprognostic (6.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.14e-1)" "unprognostic (4.99e-3)" "unprognostic (3.05e-2)" "unprognostic (5.39e-6)" "unprognostic (4.29e-2)" "unprognostic (3.74e-2)" "unprognostic (4.50e-1)" "unprognostic (1.25e-1)" WNT11 ENSG00000085741 "Wnt family member 11" O96014 11 76186325-76210736 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.9" "Cell type enhanced" "Detected in some" "Adipocytes: 33.5;Fibroblasts: 23.2;Skeletal myocytes: 7.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 6 "NK-cells: 2.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 27.9" "Kidney - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050101 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 53: Fibroblasts - ECM organization" 17 "HPA050101: AB_2681015" "prognostic favorable (5.97e-4)" "unprognostic (9.27e-2)" "unprognostic (2.01e-2)" "unprognostic (2.52e-1)" "unprognostic (1.87e-2)" "unprognostic (8.43e-2)" "unprognostic (7.88e-2)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (3.85e-2)" "unprognostic (2.88e-2)" "unprognostic (4.36e-2)" "unprognostic (3.10e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (3.16e-3)" "unprognostic (1.09e-3)" WNT16 ENSG00000002745 "Wnt family member 16" Q9UBV4 7 121325367-121341104 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 5.8;skin 1: 20.0" "Cell type enhanced" "Detected in some" "B-cells: 3.8;Basal keratinocytes: 6.0;Endometrial stromal cells: 3.3;Inhibitory neurons: 5.8;Microglial cells: 3.6;Suprabasal keratinocytes: 6.3" "Cancer enhanced" "Detected in some" "lung cancer: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 145 "memory B-cell: 15.6;naive B-cell: 15.5" "Lineage enriched" "Detected in single" 146 "B-cells: 15.6" "Cancer enhanced" "Detected in many" "Leukemia: 9.8" "Colon - Enteric glia cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 13: Skin - Cornification" "Cluster 23: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" "unprognostic (6.53e-2)" "unprognostic (3.63e-2)" "unprognostic (7.24e-2)" "unprognostic (1.90e-2)" "unprognostic (2.94e-3)" "unprognostic (5.23e-2)" "unprognostic (1.77e-2)" "unprognostic (1.16e-1)" "unprognostic (1.12e-1)" "unprognostic (1.94e-1)" "unprognostic (3.77e-1)" "unprognostic (2.18e-2)" "unprognostic (3.57e-10)" "unprognostic (5.89e-3)" "unprognostic (2.73e-1)" "unprognostic (5.50e-2)" "unprognostic (1.66e-1)" WNT2 "INT1L1, IRP" ENSG00000105989 "Wnt family member 2" P09544 7 117275451-117323152 "Cancer-related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 38.6" "Cell type enhanced" "Detected in some" "Early spermatids: 31.6;Endometrial stromal cells: 34.6;Fibroblasts: 12.0;Late spermatids: 17.5;Mesothelial cells: 9.9;Smooth muscle cells: 41.8;Spermatocytes: 11.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.7" "Adipose subcutaneous - Adipose progenitor cells, Liver - Sinusoid Endothelial cells, Testis - Early spermatids" "Region enhanced" "Detected in many" "basal ganglia: 12.6" "Low region specificity" "Detected in many" HPA020920 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" Vesicles "HPA020920: AB_1858850" "unprognostic (1.90e-1)" "unprognostic (6.97e-2)" "unprognostic (2.88e-2)" "unprognostic (4.11e-3)" "unprognostic (9.14e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-2)" "unprognostic (2.75e-1)" "unprognostic (2.74e-1)" "unprognostic (5.70e-2)" "unprognostic (1.36e-2)" "unprognostic (1.41e-1)" "unprognostic (3.43e-1)" "unprognostic (4.05e-2)" "unprognostic (2.50e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-1)" WNT2B "WNT13, XWNT2" ENSG00000134245 "Wnt family member 2B" Q93097 1 112466541-112530165 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leydig cells: 81.7;Peritubular cells: 190.0" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Testis - Peritubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047274, HPA066368" Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Ovarian stromal cells - Transcription" Vesicles Nucleoplasm "HPA047274: AB_2732539, HPA066368: AB_2685664" "unprognostic (2.08e-3)" "unprognostic (2.06e-3)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (9.42e-2)" "unprognostic (4.90e-3)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (5.65e-4)" "unprognostic (5.41e-2)" "unprognostic (7.64e-2)" "unprognostic (4.80e-2)" "unprognostic (2.49e-2)" WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.0;skin 1: 26.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 26.2;Early spermatids: 12.3;Late spermatids: 68.9;Suprabasal keratinocytes: 13.6" "Cancer enriched" "Detected in many" 6 "testis cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Late spermatids - Unknown function" 2 Vesicles "HPA049893: " "unprognostic (1.84e-1)" "unprognostic (2.90e-2)" "unprognostic (2.35e-1)" "unprognostic (6.41e-4)" "unprognostic (4.73e-2)" "unprognostic (5.26e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (4.97e-2)" "unprognostic (2.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-8)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 10.3;Basal keratinocytes: 2.3;Basal squamous epithelial cells: 4.0;Distal tubular cells: 3.1;Salivary duct cells: 3.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.0;head and neck cancer: 2.9" "Breast - Breast myoepithelial cells, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Connective tissue cells - ECM organization" 4 Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" WNT4 WNT-4 ENSG00000162552 "Wnt family member 4" P56705 1 22117313-22143969 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 39.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 22.8;Basal respiratory cells: 42.5;Breast glandular cells: 24.0;Breast myoepithelial cells: 26.3;Endometrial stromal cells: 76.1;Suprabasal keratinocytes: 52.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 9.8" "Lung - Alveolar cells type 2, Pancreas - Alpha cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011397 Uncertain Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 13: Skin - Cornification" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 1 Vesicles "HPA011397: AB_1858854" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (6.67e-3)" "unprognostic (1.75e-2)" "unprognostic (7.17e-2)" "unprognostic (4.30e-3)" "unprognostic (2.77e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.34e-4)" "unprognostic (2.14e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (4.21e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-2)" "unprognostic (9.49e-2)" WNT5A hWNT5A ENSG00000114251 "Wnt family member 5A" P41221 3 55465715-55490539 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 26.6;salivary gland: 33.5" "Cell type enhanced" "Detected in many" "Club cells: 52.8;Endometrial stromal cells: 91.3;Serous glandular cells: 71.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 91.1" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 75: Serous glandular cells - Salivary secretion" "unprognostic (2.34e-3)" "unprognostic (1.35e-1)" "prognostic favorable (2.94e-5)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (1.14e-1)" "unprognostic (2.16e-2)" "unprognostic (3.91e-2)" "unprognostic (5.89e-2)" "unprognostic (9.58e-2)" "unprognostic (8.34e-3)" "unprognostic (1.10e-1)" "unprognostic (4.81e-3)" "unprognostic (9.70e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-3)" "unprognostic (3.63e-2)" WNT5B ENSG00000111186 "Wnt family member 5B" Q9H1J7 12 1529891-1647212 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 19.3;Club cells: 20.2;Microglial cells: 18.8;Muller glia cells: 33.9;Prostatic glandular cells: 18.0;Salivary duct cells: 23.2" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;eosinophil: 1.5" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 90.7" "Kidney - Fibroblasts, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061991 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" Vesicles "HPA061991: " "unprognostic (7.44e-2)" "unprognostic (5.59e-2)" "unprognostic (8.14e-2)" "unprognostic (3.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (5.53e-3)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (4.08e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-3)" "unprognostic (1.90e-1)" "unprognostic (2.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.71e-2)" WNT6 ENSG00000115596 "Wnt family member 6" Q9Y6F9 2 218859805-218874233 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.3" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 297.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 8.7" "Group enriched" "Detected in many" 5 "basal ganglia: 20.5;thalamus: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 10.2" HPA070759 Approved "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA070759: AB_2732164" "unprognostic (1.86e-2)" "unprognostic (6.03e-2)" "unprognostic (5.14e-2)" "unprognostic (2.06e-1)" "unprognostic (5.32e-2)" "unprognostic (7.34e-2)" "unprognostic (8.08e-3)" "unprognostic (4.73e-2)" "unprognostic (1.27e-2)" "unprognostic (1.19e-1)" "unprognostic (1.21e-2)" "unprognostic (2.66e-1)" "unprognostic (1.24e-3)" "unprognostic (5.26e-2)" "unprognostic (4.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" WNT7A Wnt-7a ENSG00000154764 "Wnt family member 7A" O00755 3 13816258-13880071 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0;gallbladder: 2.2;placenta: 2.6" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 67.1;Extravillous trophoblasts: 164.7;Syncytiotrophoblasts: 167.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.2;ovarian cancer: 11.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory CD4 T-cell: 1.7;naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 18 "T-cells: 1.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 23.8;Uterine cancer: 24.6" "Lung - Alveolar cells type 1, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015719, CAB025894" Approved "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 4: Extravillous trophoblasts - Unknown function" 5 "CAB025894: , HPA015719: AB_1858856" "unprognostic (1.26e-2)" "unprognostic (4.60e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.96e-5)" "unprognostic (3.02e-1)" "unprognostic (1.14e-3)" "unprognostic (2.49e-1)" "unprognostic (3.32e-4)" "unprognostic (2.20e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.03e-6)" "unprognostic (7.89e-2)" "unprognostic (3.78e-2)" "unprognostic (6.49e-4)" "unprognostic (1.90e-1)" "unprognostic (3.74e-1)" "unprognostic (8.88e-3)" WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.3;esophagus: 12.0;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 17.0;Basal keratinocytes: 30.4;Basal respiratory cells: 14.8;Basal squamous epithelial cells: 37.0;Club cells: 36.9;Squamous epithelial cells: 18.7;Suprabasal keratinocytes: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "unprognostic (2.02e-3)" "unprognostic (7.83e-3)" "unprognostic (8.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "unprognostic (3.85e-3)" "unprognostic (1.69e-2)" "unprognostic (8.58e-4)" "unprognostic (1.90e-1)" "unprognostic (6.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" WNT8A WNT8D ENSG00000061492 "Wnt family member 8A" Q9H1J5 5 138083990-138092365 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.7;Inhibitory neurons: 1.5" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.0" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA038539 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA038539: AB_10669646" "unprognostic (1.11e-5)" "unprognostic (4.11e-2)" "unprognostic (4.11e-2)" "unprognostic (5.32e-2)" WNT8B ENSG00000075290 "Wnt family member 8B" Q93098 10 100463009-100483744 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "parathyroid gland: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 2.4;prostate cancer: 1.8" "Kidney - Podocytes, Prostate - Prostate basal glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA036570 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 15: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "HPA036570: AB_10670113" "unprognostic (6.92e-2)" "unprognostic (1.57e-1)" "unprognostic (7.13e-2)" "unprognostic (6.67e-2)" "unprognostic (3.88e-1)" "unprognostic (1.90e-1)" "unprognostic (2.64e-1)" "unprognostic (9.16e-4)" "unprognostic (1.95e-2)" "unprognostic (1.02e-1)" "unprognostic (1.53e-1)" "unprognostic (7.83e-2)" "unprognostic (2.42e-3)" "unprognostic (5.02e-2)" "unprognostic (1.63e-1)" "unprognostic (2.68e-2)" "unprognostic (1.24e-2)" WNT9A WNT14 ENSG00000143816 "Wnt family member 9A" O14904 1 227918656-227947932 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.0;skeletal muscle: 25.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.5;Basal squamous epithelial cells: 7.3;Ciliated cells: 7.9;Skeletal myocytes: 9.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 17.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Ciliated cells - Cilium assembly" 1 "unprognostic (2.27e-2)" "unprognostic (3.24e-1)" "unprognostic (3.77e-3)" "unprognostic (4.57e-2)" "unprognostic (2.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.39e-2)" "unprognostic (1.44e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.48e-1)" "unprognostic (1.38e-2)" "unprognostic (1.70e-2)" "unprognostic (3.72e-2)" "unprognostic (8.71e-2)" "unprognostic (5.04e-2)" "unprognostic (9.93e-2)" WNT9B "WNT14B, WNT15" ENSG00000158955 "Wnt family member 9B" O14905 17 46833201-46886730 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 13.5;seminal vesicle: 9.4" "Group enriched" "Detected in some" 6 "Basal prostatic cells: 4.4;Collecting duct cells: 9.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "testis cancer: 6.8" "Region enriched" "Detected in single" 7 "thalamus: 5.8" "Low region specificity" "Detected in all" "HPA058361, HPA059572" Approved Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Vesicles "HPA058361: AB_2683691, HPA059572: AB_2684067" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (3.18e-2)" "unprognostic (7.48e-3)" "unprognostic (3.37e-3)" "unprognostic (1.78e-1)" "unprognostic (8.11e-2)" "unprognostic (1.59e-2)" "unprognostic (3.66e-2)" "unprognostic (6.19e-4)" "unprognostic (1.13e-1)" "unprognostic (3.69e-2)" "unprognostic (7.52e-4)" "unprognostic (1.27e-1)" "unprognostic (2.70e-1)" "unprognostic (1.37e-1)" WSCD1 KIAA0523 ENSG00000179314 "WSC domain containing 1" Q658N2 17 6057807-6124427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.8;lymphoid tissue: 12.6" "Group enriched" "Detected in many" 4 "Early spermatids: 62.1;Late spermatids: 108.2;Oligodendrocyte precursor cells: 103.3" "Cancer enriched" "Detected in many" 4 "glioma: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 24.7" "Prostate - Endothelial cells, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015919 Uncertain Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 76: Oligodendrocyte precursor - Unknown function" Nucleoplasm "Golgi apparatus" "HPA015919: AB_2216211" "unprognostic (1.50e-1)" "unprognostic (7.10e-2)" "unprognostic (5.32e-2)" "unprognostic (1.15e-2)" "unprognostic (2.61e-1)" "unprognostic (4.18e-2)" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (3.59e-2)" "unprognostic (1.69e-1)" "unprognostic (3.46e-4)" "unprognostic (2.08e-1)" "unprognostic (1.18e-2)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" WSCD2 KIAA0789 ENSG00000075035 "WSC domain containing 2" Q2TBF2 12 108129288-108250537 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "brain: 107.8" "Group enriched" "Detected in some" 4 "Bipolar cells: 34.9;Excitatory neurons: 29.1;Horizontal cells: 21.4;Inhibitory neurons: 26.5;Oligodendrocyte precursor cells: 9.0" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Pancreas - Beta cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013346, HPA048133" Approved Uncertain Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 25: Bipolar cells - Visual perception" Nucleoplasm "HPA013346: AB_1858865, HPA048133: AB_2797236" "unprognostic (1.50e-1)" "unprognostic (1.64e-3)" "unprognostic (1.50e-2)" "unprognostic (4.27e-3)" "unprognostic (1.68e-1)" "unprognostic (3.43e-1)" "unprognostic (1.80e-2)" "unprognostic (3.43e-3)" "unprognostic (3.03e-2)" "unprognostic (3.05e-1)" "unprognostic (3.15e-1)" "unprognostic (7.43e-2)" "unprognostic (5.99e-2)" "unprognostic (3.73e-2)" "unprognostic (2.11e-1)" "unprognostic (2.32e-3)" "unprognostic (7.62e-3)" XCL1 "ATAC, LPTN, LTN, SCM-1, SCM-1a, SCYC1" ENSG00000143184 "X-C motif chemokine ligand 1" P47992 1 168576605-168582069 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.5" "Group enriched" "Detected in many" 22 "NK-cells: 198.4;T-cells: 212.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Immune cell enriched" "Detected in many" 14 "NK-cell: 88.6" "Lineage enriched" "Detected in many" 14 "NK-cells: 88.6" "Cancer enhanced" "Detected in many" "testis cancer: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Prostate - T-cells, Thyroid - T-cells" HPA057725 Approved "Secreted to blood" Chemokine NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 24: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 3 "HPA057725: AB_2683511" "unprognostic (5.38e-3)" "unprognostic (5.72e-2)" "unprognostic (8.23e-3)" "unprognostic (4.19e-3)" "unprognostic (1.43e-1)" "unprognostic (6.10e-2)" "unprognostic (2.96e-1)" "unprognostic (4.27e-2)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (4.61e-1)" "unprognostic (8.85e-2)" "unprognostic (5.34e-10)" "unprognostic (1.96e-1)" "unprognostic (1.32e-1)" "unprognostic (5.47e-2)" "unprognostic (2.15e-2)" XCL2 "SCM-1b, SCYC2" ENSG00000143185 "X-C motif chemokine ligand 2" Q9UBD3 1 168540768-168543997 "Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.9;lymphoid tissue: 13.1" "Group enriched" "Detected in some" 14 "NK-cells: 520.2;T-cells: 237.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "NK-cell: 424.2" "Lineage enriched" "Detected in many" 8 "NK-cells: 424.2" "Cancer enriched" "Detected in some" 7 "Sarcoma: 7.3" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Thyroid - T-cells" HPA057725 Approved "Secreted to blood" Chemokine NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 54: Non-specific - Transcription" "Cluster 19: NK-cells - Adaptive immune response" 5 "HPA057725: AB_2683511" "unprognostic (9.88e-3)" "unprognostic (7.89e-3)" "unprognostic (4.77e-2)" "unprognostic (9.32e-3)" "unprognostic (8.21e-2)" "unprognostic (6.79e-4)" "unprognostic (9.33e-2)" "prognostic favorable (3.17e-4)" "unprognostic (1.58e-3)" "unprognostic (6.26e-2)" "unprognostic (2.02e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (8.36e-9)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "unprognostic (3.02e-2)" "unprognostic (1.06e-1)" XDH "XO, XOR" ENSG00000158125 "Xanthine dehydrogenase" P47989 2 31334321-31414742 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 40.8;intestine: 48.1;liver: 66.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 252.4;Distal enterocytes: 68.7;Hepatocytes: 41.3;Proximal enterocytes: 98.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.0" "Colon - Colon enterocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062641, HPA069323" Supported Uncertain Nucleoplasm,Nucleoli "Intracellular and membrane" Enzyme No No 77000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 17: Breast glandular cells - Lactation" Nucleoplasm Nucleoli "HPA062641: AB_2684816, HPA069323: AB_2686121" "unprognostic (8.58e-2)" "unprognostic (4.07e-2)" "unprognostic (1.34e-2)" "unprognostic (1.79e-1)" "unprognostic (2.08e-2)" "unprognostic (7.06e-2)" "unprognostic (4.38e-3)" "unprognostic (7.48e-3)" "unprognostic (3.55e-1)" "unprognostic (3.60e-2)" "unprognostic (3.95e-3)" "unprognostic (3.51e-2)" "unprognostic (1.24e-6)" "unprognostic (2.25e-1)" "unprognostic (5.25e-2)" "unprognostic (2.54e-1)" "prognostic favorable (8.73e-6)" XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 162.0;kidney: 150.4" "Cell type enriched" "Detected in some" 8 "Proximal enterocytes: 414.5" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.2;Leukemia: 1.0" "Breast - Macrophages, Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Fibroblast_2, Skin - Fibroblast_2" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 2.4" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 13000000 "Cluster 33: Non-specific - ATP binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470960 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 1121.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 4 "monocytes: 2.0" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" Enzyme NA NA 150000 "Cluster 40: Monocytes - Innate immune response" "Cluster 17: Neuronal - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" XYLT2 "PXYLT2, XT-II" ENSG00000015532 "Xylosyltransferase 2" Q9H1B5 17 50346126-50363138 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "stomach 1: 84.3" "Group enriched" "Detected in many" 8 "Early spermatids: 255.7;Late spermatids: 148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 1100000 "Cluster 11: T-cells - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" 1 "unprognostic (1.52e-1)" "unprognostic (2.84e-1)" "unprognostic (1.65e-1)" "unprognostic (8.07e-2)" "unprognostic (1.90e-3)" "unprognostic (1.90e-1)" "unprognostic (7.29e-3)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (2.30e-1)" "unprognostic (1.54e-2)" "unprognostic (2.81e-1)" "unprognostic (7.63e-2)" "unprognostic (5.15e-2)" "unprognostic (7.38e-2)" "unprognostic (1.52e-2)" "unprognostic (2.68e-2)" YBX1 "BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1" ENSG00000065978 "Y-box binding protein 1" P67809 1 42682418-42703805 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1967.5" "Cell type enhanced" "Detected in all" "Early spermatids: 7542.0;Late spermatids: 4465.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005875, HPA040304, HPA057159" Supported Supported "Endoplasmic reticulum,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" Transcription NA NA 1600000 "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 11: Late spermatids - Unknown function" 27 Cytosol "Endoplasmic reticulum, Vesicles, Plasma membrane" "CAB005875: AB_2219278, HPA040304: AB_10795364, HPA057159: AB_2683355" "unprognostic (8.59e-2)" "unprognostic (5.16e-2)" "unprognostic (9.27e-3)" "unprognostic (2.68e-3)" "unprognostic (7.76e-2)" "unprognostic (8.03e-3)" "prognostic unfavorable (9.87e-10)" "unprognostic (2.80e-2)" "unprognostic (2.31e-2)" "unprognostic (2.79e-3)" "unprognostic (7.51e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (3.59e-7)" "unprognostic (3.66e-2)" "unprognostic (2.44e-1)" "unprognostic (1.94e-2)" "unprognostic (3.25e-1)" ZBED3 MGC15435 ENSG00000132846 "Zinc finger BED-type containing 3" Q96IU2 5 77072072-77087285 "Predicted intracellular proteins, Predicted secreted proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA055995 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" Other NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 33: Non-specific - DNA binding" "Plasma membrane" Nucleoplasm "HPA055995: AB_2683000" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (3.78e-2)" "unprognostic (4.02e-2)" "unprognostic (2.97e-1)" "unprognostic (1.45e-2)" "unprognostic (6.96e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "unprognostic (3.63e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.08e-1)" "unprognostic (1.92e-1)" "unprognostic (5.41e-2)" "unprognostic (1.08e-1)" ZG16 "hZG16, JCLN, JCLN1, ZG16A" ENSG00000174992 "Zymogen granule protein 16" O60844 16 29778256-29782973 "Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "intestine: 463.2" "Cell type enriched" "Detected in some" 28 "Intestinal goblet cells: 46456.4" "Cancer enriched" "Detected in some" 6 "colorectal cancer: 21.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Liver - Hepatocytes, Testis - Early spermatids" "Not detected" "Not detected" "HPA052066, HPA052512" Enhanced "Secreted to digestive system" Transport NA NA 1300000 "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" 7 "HPA052066: AB_2681716, HPA052512: AB_2681857" "unprognostic (1.64e-2)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (8.20e-2)" "unprognostic (3.50e-2)" "unprognostic (1.93e-2)" "unprognostic (5.14e-2)" "unprognostic (1.65e-1)" "unprognostic (7.77e-2)" "unprognostic (3.27e-1)" "unprognostic (2.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" ZG16B "HRPE773, JCLN2, PRO1567" ENSG00000162078 "Zymogen granule protein 16B" Q96DA0 16 2830253-2839585 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 827 "salivary gland: 83030.7" "Cell type enriched" "Detected in many" 8 "Serous glandular cells: 26030.4" "Cancer enhanced" "Detected in many" "prostate cancer: 47.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "intermediate monocyte: 8.1;non-classical monocyte: 9.3" "Lineage enriched" "Detected in single" 15 "monocytes: 9.3" "Cancer enhanced" "Detected in many" "breast cancer: 12.8" "Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "HPA041125, HPA053549" Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" "No annotated function" NA NA 690000 "Cluster 40: Monocytes - Innate immune response" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 27: Breast cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 6 Vesicles Nucleoplasm "HPA041125: AB_10794264, HPA053549: AB_2682184" "unprognostic (5.29e-2)" "unprognostic (2.71e-1)" "unprognostic (4.37e-2)" "prognostic favorable (3.48e-6)" "unprognostic (1.39e-3)" "unprognostic (1.94e-2)" "unprognostic (2.34e-3)" "unprognostic (4.13e-2)" "unprognostic (1.01e-1)" "unprognostic (3.45e-3)" "unprognostic (1.37e-1)" "unprognostic (1.47e-2)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.17e-1)" "unprognostic (1.04e-1)" "unprognostic (8.33e-2)" ZNF34 KOX32 ENSG00000196378 "Zinc finger protein 34" Q8IZ26 8 144772224-144787345 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053925, HPA060755, HPA066805" Uncertain Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" Transcription NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Neuronal - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 2 Nucleoplasm Cytosol "HPA053925: AB_2682311, HPA060755: AB_2684354, HPA066805: AB_2685725" "unprognostic (2.54e-1)" "unprognostic (3.50e-1)" "unprognostic (5.01e-2)" "unprognostic (7.60e-2)" "unprognostic (1.98e-1)" "unprognostic (1.67e-2)" "unprognostic (3.26e-2)" "unprognostic (3.54e-2)" "unprognostic (2.85e-2)" "unprognostic (1.40e-2)" "unprognostic (9.84e-3)" "unprognostic (1.46e-1)" "unprognostic (3.46e-3)" "unprognostic (5.80e-2)" "unprognostic (2.09e-3)" "unprognostic (1.56e-1)" "unprognostic (1.30e-1)" ZNF433 FLJ40981 ENSG00000197647 "Zinc finger protein 433" Q8N7K0 19 12014715-12035741 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.1" "Group enriched" "Detected in many" 4 "Early spermatids: 210.6;Late spermatids: 142.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" HPA073724 Enhanced Approved "Nuclear bodies" "Intracellular and membrane" Transcription NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 78: Testis - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 11: Late spermatids - Unknown function" 5 "Nuclear bodies" "HPA073724: AB_2686631" "unprognostic (3.48e-2)" "unprognostic (1.24e-1)" "unprognostic (9.90e-2)" "unprognostic (6.84e-2)" "unprognostic (2.67e-1)" "unprognostic (3.92e-2)" "unprognostic (1.13e-1)" "unprognostic (4.16e-2)" "unprognostic (3.66e-3)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (1.36e-3)" "prognostic favorable (8.33e-15)" "unprognostic (1.06e-2)" "unprognostic (6.95e-2)" "unprognostic (9.20e-2)" "unprognostic (2.69e-2)" ZNF449 "FLJ23614, ZSCAN19" ENSG00000173275 "Zinc finger protein 449" Q6P9G9 X 135344796-135363413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 15.2;Inhibitory neurons: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018079 Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" Transcription NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 55: Non-specific - Transcription" 4 "Nucleoplasm, Cytosol" "HPA018079: AB_1859277" "unprognostic (5.51e-3)" "unprognostic (1.64e-1)" "unprognostic (6.94e-2)" "unprognostic (2.74e-1)" "unprognostic (1.30e-1)" "unprognostic (2.20e-1)" "unprognostic (3.74e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-2)" "unprognostic (4.86e-2)" "unprognostic (2.69e-1)" "unprognostic (5.31e-2)" "unprognostic (1.34e-3)" "unprognostic (1.28e-1)" "unprognostic (2.54e-1)" "unprognostic (9.61e-2)" "unprognostic (4.22e-2)" ZNF488 FLJ32104 ENSG00000265763 "Zinc finger protein 488" Q96MN9 10 47365496-47384293 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 61.9;intestine: 21.8" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.6;Distal tubular cells: 12.3;Horizontal cells: 6.9;Oligodendrocyte precursor cells: 9.4;Oligodendrocytes: 18.7;Proximal enterocytes: 19.8;Syncytiotrophoblasts: 33.6" "Cancer enhanced" "Detected in many" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035957, HPA035958" Supported Nucleoplasm,Cytosol "Intracellular and membrane" Transcription NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" 10 "Nucleoplasm, Cytosol" "HPA035957: AB_10672234, HPA035958: AB_2674887" "unprognostic (3.29e-2)" "unprognostic (1.05e-2)" "unprognostic (7.87e-2)" "unprognostic (1.49e-4)" "unprognostic (1.16e-1)" "unprognostic (8.85e-2)" "unprognostic (1.60e-3)" "unprognostic (2.13e-2)" "unprognostic (3.11e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (4.02e-7)" "unprognostic (3.60e-1)" "unprognostic (6.62e-5)" "unprognostic (2.76e-1)" "unprognostic (4.47e-1)" "unprognostic (8.10e-2)" "unprognostic (3.18e-2)" ZNF511 "MGC30006, Zfp511" ENSG00000198546 "Zinc finger protein 511" Q8NB15 10 133308914-133313162 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035360 Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" "Intracellular and membrane" Transcription NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 16: Intestinal goblet cells - Mucin production" 12 "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: AB_10601931" "unprognostic (3.35e-2)" "unprognostic (2.19e-1)" "unprognostic (1.91e-1)" "unprognostic (8.84e-2)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (3.04e-1)" "unprognostic (1.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.64e-2)" "unprognostic (1.40e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.94e-2)" "unprognostic (3.91e-2)" "unprognostic (2.55e-1)" "unprognostic (4.52e-2)" ZNF570 FLJ30791 ENSG00000171827 "Zinc finger protein 570" Q96NI8 19 37467585-37488652 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028881 Uncertain Approved Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 21: Early spermatids - Spermatogenesis" Nucleoplasm "HPA028881: AB_10603938" "unprognostic (2.93e-2)" "unprognostic (1.55e-1)" "unprognostic (3.71e-2)" "unprognostic (1.24e-1)" "unprognostic (1.70e-2)" "unprognostic (1.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.23e-1)" "unprognostic (2.01e-2)" "unprognostic (1.12e-1)" "unprognostic (6.54e-2)" "unprognostic (4.59e-2)" "prognostic favorable (4.06e-5)" "unprognostic (5.30e-2)" "unprognostic (2.85e-2)" "unprognostic (3.12e-2)" "unprognostic (2.20e-3)" ZP1 ZPB1 ENSG00000149506 "Zona pellucida glycoprotein 1" P60852 11 60867542-60875693 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Early spermatids: 32.0;Late spermatids: 86.5" "Cancer enhanced" "Detected in single" "prostate cancer: 0.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 32 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 32 "dendritic cells: 3.1" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Secreted in female reproductive system" Other NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Late spermatids - Unknown function" "unprognostic (6.40e-3)" "unprognostic (2.18e-4)" "unprognostic (1.63e-1)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (7.02e-2)" "unprognostic (8.27e-2)" "unprognostic (9.95e-2)" "unprognostic (1.94e-2)" "unprognostic (8.15e-3)" "unprognostic (2.52e-1)" "unprognostic (9.25e-4)" "unprognostic (5.31e-13)" "unprognostic (4.13e-2)" "unprognostic (2.38e-1)" "unprognostic (6.27e-2)" "unprognostic (5.61e-2)" ZP2 ZPA ENSG00000103310 "Zona pellucida glycoprotein 2" Q05996 16 21197450-21214510 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "brain: 32.3" "Cell type enriched" "Detected in some" 5 "Oocytes: 36.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 16 "cerebellum: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA011296 Enhanced "Secreted in female reproductive system" Receptor NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 44: Oocytes - Unknown function" "HPA011296: AB_1859485" "unprognostic (2.35e-2)" "unprognostic (3.12e-2)" "unprognostic (6.60e-2)" "unprognostic (9.83e-2)" "unprognostic (3.44e-3)" "unprognostic (3.12e-1)" "unprognostic (1.66e-1)" "unprognostic (4.41e-2)" ZP3 "ZP3-372, ZP3-424, ZP3A, ZP3B, ZPC" ENSG00000188372 "Zona pellucida glycoprotein 3" P21754 7 76397518-76442071 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 19.5" "Cell type enriched" "Detected in many" 26 "Oocytes: 1882.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 42.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054061, HPA071198" Supported "Secreted in female reproductive system" Receptor NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 59: Fallopian tube - Tissue development" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Oocytes - Unknown function" 4 "HPA054061: AB_2682363, HPA071198: " "unprognostic (6.48e-2)" "unprognostic (3.08e-1)" "unprognostic (7.74e-2)" "unprognostic (1.59e-1)" "unprognostic (9.04e-2)" "unprognostic (2.68e-2)" "unprognostic (1.99e-3)" "unprognostic (1.29e-1)" "unprognostic (9.20e-2)" "unprognostic (1.94e-1)" "unprognostic (3.10e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (1.02e-6)" "unprognostic (1.33e-1)" "unprognostic (1.42e-2)" "unprognostic (6.72e-2)" "unprognostic (2.13e-1)" ZP4 "ZP1B, ZPB, ZPB2" ENSG00000116996 "Zona pellucida glycoprotein 4" Q12836 1 237877864-237890922 "Predicted membrane proteins, Predicted secreted proteins" Fertilization Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "ovary: 3.6" "Cell type enriched" "Detected in some" 25 "Oocytes: 176.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA008547 Enhanced "Secreted in female reproductive system" Receptor NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Oocytes - Unknown function" 1 "HPA008547: AB_1080766" "unprognostic (7.12e-2)" "unprognostic (2.70e-1)" "unprognostic (4.59e-2)" ZPBP "SP38, ZPBP1" ENSG00000042813 "Zona pellucida binding protein" Q9BS86 7 49850421-50121329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 138.9" "Group enriched" "Detected in some" 10 "Early spermatids: 1345.0;Spermatocytes: 584.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058673 Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 6: Leukemia - Signal transduction" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA058673: AB_2683794" "unprognostic (1.16e-1)" "unprognostic (6.46e-2)" "unprognostic (7.80e-2)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.15e-7)" "unprognostic (9.49e-2)" "unprognostic (2.34e-4)" ZPBP2 "MGC41930, ZPBPL" ENSG00000186075 "Zona pellucida binding protein 2" Q6X784 17 39868202-39877896 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 100 "testis: 92.5" "Group enriched" "Detected in some" 6 "Early spermatids: 364.4;Spermatocytes: 511.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "lymphoma: 2.7" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027997, HPA053070" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 10: Testis - Spermatid development" "Cluster 9: Non-specific - Receptor signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "HPA027997: AB_1859488, HPA053070: AB_2682033" "unprognostic (2.14e-2)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (2.87e-1)" "unprognostic (5.39e-1)" "unprognostic (2.54e-3)" ZPLD1 ENSG00000170044 "Zona pellucida like domain containing 1" Q8TCW7 3 102099244-102479841 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.2;retina: 2.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 5.7;Ductal cells: 3.7;Early spermatids: 2.7;Late spermatids: 6.1;Muller glia cells: 14.6;Pancreatic endocrine cells: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 39.2" "Colon - Colon enteroendocrine cells" "Region enriched" "Detected in single" 7 "olfactory bulb: 2.8" "Not detected" "Not detected" HPA077519 Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" Nucleoplasm "HPA077519: AB_2732349" "unprognostic (2.49e-1)" "unprognostic (2.83e-3)" "unprognostic (6.38e-3)" "unprognostic (1.88e-1)" "unprognostic (5.02e-2)" "unprognostic (1.37e-2)" "unprognostic (2.68e-1)" "unprognostic (2.63e-1)" "unprognostic (4.63e-1)" "unprognostic (2.89e-4)" "unprognostic (4.59e-2)" "unprognostic (1.05e-3)" "unprognostic (1.97e-2)" "unprognostic (9.65e-2)" "unprognostic (1.41e-1)" "unprognostic (1.23e-2)"