TAS2R42 hT2R55 T2R24 T2R55 TAS2R55

uncertain adrenal gland glandular cells moderate appendix glandular cells weak appendix lymphoid tissue weak bone marrow hematopoietic cells negative breast adipocytes negative breast glandular cells weak breast myoepithelial cells negative bronchus respiratory epithelial cells moderate cerebellum cells in granular layer moderate cerebellum cells in molecular layer negative cerebellum Purkinje cells moderate cerebral cortex endothelial cells negative cerebral cortex glial cells weak cerebral cortex neuronal cells moderate cerebral cortex neuropil weak cervix, uterine glandular cells negative cervix, uterine squamous epithelial cells negative colon endothelial cells moderate colon glandular cells moderate colon peripheral nerve/ganglion weak duodenum glandular cells weak epididymis glandular cells moderate esophagus squamous epithelial cells moderate fallopian tube glandular cells moderate gallbladder glandular cells moderate heart muscle myocytes moderate hippocampus glial cells negative hippocampus neuronal cells weak kidney cells in glomeruli strong kidney cells in tubules moderate lateral ventricle glial cells weak lateral ventricle neuronal cells weak liver bile duct cells weak liver hepatocytes negative lung macrophages weak lung pneumocytes weak lymph node non-germinal center cells negative nasopharynx respiratory epithelial cells negative oral mucosa squamous epithelial cells strong ovary ovarian stroma cells negative pancreas exocrine glandular cells moderate pancreas islets of Langerhans moderate parathyroid gland glandular cells weak placenta trophoblastic cells weak prostate glandular cells weak rectum glandular cells moderate salivary gland glandular cells weak seminal vesicle glandular cells moderate skeletal muscle myocytes strong skin fibroblasts negative skin keratinocytes negative skin Langerhans negative skin melanocytes negative small intestine glandular cells moderate smooth muscle smooth muscle cells negative soft tissue 1 adipocytes negative soft tissue 1 fibroblasts weak soft tissue 1 peripheral nerve weak soft tissue 2 adipocytes weak soft tissue 2 chondrocytes weak soft tissue 2 fibroblasts weak spleen cells in red pulp negative spleen cells in white pulp negative stomach, lower glandular cells moderate stomach, upper glandular cells moderate testis cells in seminiferus ducts strong testis Leydig cells weak thyroid gland glandular cells weak tonsil germinal center cells moderate tonsil non-germinal center cells negative tonsil squamous epithelial cells moderate urinary bladder urothelial cells weak uterus, post-menopause cells in endometrial stroma weak uterus, post-menopause glandular cells weak uterus, pre-menopause cells in endometrial stroma negative uterus, pre-menopause glandular cells negative vagina squamous epithelial cells moderate vulva/anal skin epidermal cells weak

uncertain nucleus but not nucleoli cytoskeleton (actin filaments) focal adhesions

U-251 MG Not detected A-549 Not detected CACO-2 Not detected Hep-G2 Not detected HeLa Not detected MCF-7 Not detected PC-3 Not detected RT-4 Not detected A-431 Not detected U-2 OS Not detected HEK 293 Not detected SLVRHTRNLKLSSLGSRDSSTEAHRRAMK

uncertain adrenal gland glandular cells moderate appendix glandular cells weak appendix lymphoid tissue weak bone marrow hematopoietic cells negative breast adipocytes negative breast glandular cells weak breast myoepithelial cells negative bronchus respiratory epithelial cells moderate cerebellum cells in granular layer moderate cerebellum cells in molecular layer negative cerebellum Purkinje cells moderate cerebral cortex endothelial cells negative cerebral cortex glial cells weak cerebral cortex neuronal cells moderate cerebral cortex neuropil weak cervix, uterine glandular cells negative cervix, uterine squamous epithelial cells negative colon endothelial cells moderate colon glandular cells moderate colon peripheral nerve/ganglion weak duodenum glandular cells weak epididymis glandular cells moderate esophagus squamous epithelial cells moderate fallopian tube glandular cells moderate gallbladder glandular cells moderate heart muscle myocytes moderate hippocampus glial cells negative hippocampus neuronal cells weak kidney cells in glomeruli strong kidney cells in tubules moderate lateral ventricle glial cells weak lateral ventricle neuronal cells weak liver bile duct cells weak liver hepatocytes negative lung macrophages weak lung pneumocytes weak lymph node non-germinal center cells negative nasopharynx respiratory epithelial cells negative oral mucosa squamous epithelial cells strong ovary ovarian stroma cells negative pancreas exocrine glandular cells moderate pancreas islets of Langerhans moderate parathyroid gland glandular cells weak placenta trophoblastic cells weak prostate glandular cells weak rectum glandular cells moderate salivary gland glandular cells weak seminal vesicle glandular cells moderate skeletal muscle myocytes strong skin fibroblasts negative skin keratinocytes negative skin Langerhans negative skin melanocytes negative small intestine glandular cells moderate smooth muscle smooth muscle cells negative soft tissue 1 adipocytes negative soft tissue 1 fibroblasts weak soft tissue 1 peripheral nerve weak soft tissue 2 adipocytes weak soft tissue 2 chondrocytes weak soft tissue 2 fibroblasts weak spleen cells in red pulp negative spleen cells in white pulp negative stomach, lower glandular cells moderate stomach, upper glandular cells moderate testis cells in seminiferus ducts strong testis Leydig cells weak thyroid gland glandular cells weak tonsil germinal center cells moderate tonsil non-germinal center cells negative tonsil squamous epithelial cells moderate urinary bladder urothelial cells weak uterus, post-menopause cells in endometrial stroma weak uterus, post-menopause glandular cells weak uterus, pre-menopause cells in endometrial stroma negative uterus, pre-menopause glandular cells negative vagina squamous epithelial cells moderate vulva/anal skin epidermal cells weak breast cancer tumor cells moderate weak carcinoid tumor cells strong moderate cervical cancer tumor cells moderate weak colorectal cancer tumor cells moderate weak negative endometrial cancer tumor cells moderate weak negative glioma tumor cells moderate weak negative head and neck cancer tumor cells moderate weak liver cancer tumor cells weak negative lung cancer tumor cells strong moderate weak negative lymphoma tumor cells moderate weak negative melanoma tumor cells strong moderate weak negative ovarian cancer tumor cells moderate weak pancreatic cancer tumor cells moderate weak negative prostate cancer tumor cells moderate weak negative renal cancer tumor cells moderate weak negative skin cancer tumor cells moderate weak stomach cancer tumor cells strong weak negative testis cancer tumor cells moderate weak thyroid cancer tumor cells weak urothelial cancer tumor cells strong moderate weak negative uncertain U-251 MG uncertain moderate nucleus but not nucleoli A-431 uncertain moderate nucleus but not nucleoli cytoskeleton (actin filaments) U-2 OS uncertain weak nucleus but not nucleoli cytoskeleton (actin filaments) focal adhesions uncertain supportive TAS2R60 T2R60

uncertain adrenal gland glandular cells negative appendix glandular cells negative appendix lymphoid tissue negative bone marrow hematopoietic cells moderate breast adipocytes negative breast glandular cells negative breast myoepithelial cells negative bronchus respiratory epithelial cells negative cerebellum cells in granular layer negative cerebellum cells in molecular layer negative cerebellum Purkinje cells negative cerebral cortex endothelial cells moderate cerebral cortex glial cells negative cerebral cortex neuronal cells negative cerebral cortex neuropil negative cervix, uterine glandular cells negative cervix, uterine squamous epithelial cells negative colon endothelial cells moderate colon glandular cells weak colon peripheral nerve/ganglion weak duodenum glandular cells moderate epididymis glandular cells negative esophagus squamous epithelial cells negative fallopian tube glandular cells negative gallbladder glandular cells negative heart muscle myocytes strong hippocampus glial cells negative hippocampus neuronal cells negative kidney cells in glomeruli moderate kidney cells in tubules negative lateral ventricle glial cells negative lateral ventricle neuronal cells negative liver bile duct cells weak liver hepatocytes strong lung macrophages negative lung pneumocytes negative lymph node germinal center cells negative lymph node non-germinal center cells negative nasopharynx respiratory epithelial cells negative oral mucosa squamous epithelial cells negative ovary ovarian stroma cells negative pancreas exocrine glandular cells negative pancreas islets of Langerhans negative parathyroid gland glandular cells weak placenta decidual cells weak placenta trophoblastic cells negative prostate glandular cells negative rectum glandular cells negative salivary gland glandular cells negative seminal vesicle glandular cells negative skeletal muscle myocytes negative skin fibroblasts negative skin keratinocytes negative skin Langerhans negative skin melanocytes negative small intestine glandular cells negative smooth muscle smooth muscle cells moderate soft tissue 1 adipocytes negative soft tissue 1 chondrocytes negative soft tissue 1 fibroblasts negative soft tissue 1 peripheral nerve negative soft tissue 2 adipocytes negative soft tissue 2 chondrocytes negative soft tissue 2 fibroblasts negative soft tissue 2 peripheral nerve negative spleen cells in red pulp negative spleen cells in white pulp negative stomach, lower glandular cells weak stomach, upper glandular cells weak testis cells in seminiferus ducts strong testis Leydig cells negative thyroid gland glandular cells weak tonsil germinal center cells negative tonsil non-germinal center cells negative tonsil squamous epithelial cells negative urinary bladder urothelial cells moderate uterus, post-menopause cells in endometrial stroma negative uterus, post-menopause glandular cells negative uterus, pre-menopause cells in endometrial stroma negative uterus, pre-menopause glandular cells weak vagina squamous epithelial cells negative vulva/anal skin epidermal cells weak

uncertain

U-2 OS Low U-251 MG Not detected A-549 Not detected CACO-2 Not detected Hep-G2 Not detected HeLa Not detected MCF-7 Not detected PC-3 Not detected RT-4 Not detected A-431 Not detected HEK 293 Not detected TSLGRHRKKALLTTSGFREPSVQAHIKA

uncertain adrenal gland glandular cells negative appendix glandular cells negative appendix lymphoid tissue negative bone marrow hematopoietic cells moderate breast adipocytes negative breast glandular cells negative breast myoepithelial cells negative bronchus respiratory epithelial cells negative cerebellum cells in granular layer negative cerebellum cells in molecular layer negative cerebellum Purkinje cells negative cerebral cortex endothelial cells moderate cerebral cortex glial cells negative cerebral cortex neuronal cells negative cerebral cortex neuropil negative cervix, uterine glandular cells negative cervix, uterine squamous epithelial cells negative colon endothelial cells moderate colon glandular cells weak colon peripheral nerve/ganglion weak duodenum glandular cells moderate epididymis glandular cells negative esophagus squamous epithelial cells negative fallopian tube glandular cells negative gallbladder glandular cells negative heart muscle myocytes strong hippocampus glial cells negative hippocampus neuronal cells negative kidney cells in glomeruli moderate kidney cells in tubules negative lateral ventricle glial cells negative lateral ventricle neuronal cells negative liver bile duct cells weak liver hepatocytes strong lung macrophages negative lung pneumocytes negative lymph node germinal center cells negative lymph node non-germinal center cells negative nasopharynx respiratory epithelial cells negative oral mucosa squamous epithelial cells negative ovary ovarian stroma cells negative pancreas exocrine glandular cells negative pancreas islets of Langerhans negative parathyroid gland glandular cells weak placenta decidual cells weak placenta trophoblastic cells negative prostate glandular cells negative rectum glandular cells negative salivary gland glandular cells negative seminal vesicle glandular cells negative skeletal muscle myocytes negative skin fibroblasts negative skin keratinocytes negative skin Langerhans negative skin melanocytes negative small intestine glandular cells negative smooth muscle smooth muscle cells moderate soft tissue 1 adipocytes negative soft tissue 1 chondrocytes negative soft tissue 1 fibroblasts negative soft tissue 1 peripheral nerve negative soft tissue 2 adipocytes negative soft tissue 2 chondrocytes negative soft tissue 2 fibroblasts negative soft tissue 2 peripheral nerve negative spleen cells in red pulp negative spleen cells in white pulp negative stomach, lower glandular cells weak stomach, upper glandular cells weak testis cells in seminiferus ducts strong testis Leydig cells negative thyroid gland glandular cells weak tonsil germinal center cells negative tonsil non-germinal center cells negative tonsil squamous epithelial cells negative urinary bladder urothelial cells moderate uterus, post-menopause cells in endometrial stroma negative uterus, post-menopause glandular cells negative uterus, pre-menopause cells in endometrial stroma negative uterus, pre-menopause glandular cells weak vagina squamous epithelial cells negative vulva/anal skin epidermal cells weak breast cancer tumor cells negative carcinoid tumor cells negative cervical cancer tumor cells strong negative colorectal cancer tumor cells moderate weak negative endometrial cancer tumor cells moderate weak negative glioma tumor cells negative head and neck cancer tumor cells negative liver cancer tumor cells strong moderate negative lung cancer tumor cells moderate weak negative lymphoma tumor cells negative melanoma tumor cells negative ovarian cancer tumor cells weak negative pancreatic cancer tumor cells strong moderate weak negative prostate cancer tumor cells negative renal cancer tumor cells negative skin cancer tumor cells weak negative stomach cancer tumor cells strong moderate weak negative testis cancer tumor cells moderate negative thyroid cancer tumor cells negative urothelial cancer tumor cells negative uncertain U-251 MG uncertain negative A-431 uncertain negative U-2 OS uncertain negative uncertain supportive Copyrighted by the Human Protein Atlas, http://www.proteinatlas.org/about