OR51E1 GPR136 GPR164 OR51E1P OR52A3P

low adrenal gland glandular cells none appendix glandular cells high appendix lymphoid tissue none bone marrow hematopoietic cells medium breast adipocytes none breast glandular cells low breast myoepithelial cells low bronchus respiratory epithelial cells low cerebellum cells in granular layer none cerebellum cells in molecular layer none cerebellum Purkinje cells none cerebral cortex endothelial cells none cerebral cortex glial cells none cerebral cortex neuronal cells none cerebral cortex neuropil none cervix, uterine glandular cells low cervix, uterine squamous epithelial cells medium colon endothelial cells none colon glandular cells low duodenum glandular cells low epididymis glandular cells none esophagus squamous epithelial cells low fallopian tube glandular cells none gallbladder glandular cells medium heart muscle myocytes low hippocampus glial cells none hippocampus neuronal cells none kidney cells in glomeruli none kidney cells in tubules low lateral ventricle glial cells none lateral ventricle neuronal cells none liver bile duct cells none liver hepatocytes none lung macrophages high lung pneumocytes low lymph node non-germinal center cells low nasopharynx respiratory epithelial cells medium oral mucosa squamous epithelial cells medium ovary follicle cells none ovary ovarian stroma cells none pancreas exocrine glandular cells low pancreas islets of Langerhans none parathyroid gland glandular cells low placenta decidual cells low placenta trophoblastic cells none prostate glandular cells medium rectum glandular cells high salivary gland glandular cells high seminal vesicle glandular cells low skeletal muscle myocytes none skin fibroblasts medium skin keratinocytes medium skin Langerhans medium skin melanocytes medium small intestine glandular cells low smooth muscle smooth muscle cells low soft tissue 1 adipocytes none soft tissue 1 chondrocytes medium soft tissue 1 fibroblasts low soft tissue 1 peripheral nerve none soft tissue 2 adipocytes none soft tissue 2 fibroblasts none soft tissue 2 peripheral nerve none spleen cells in red pulp low spleen cells in white pulp none stomach, lower glandular cells none stomach, upper glandular cells none testis cells in seminiferus ducts none testis Leydig cells low thyroid gland glandular cells medium tonsil germinal center cells medium tonsil non-germinal center cells medium tonsil squamous epithelial cells medium urinary bladder urothelial cells medium uterus, post-menopause cells in endometrial stroma none uterus, post-menopause glandular cells none uterus, pre-menopause cells in endometrial stroma low uterus, pre-menopause glandular cells medium vagina squamous epithelial cells medium vulva/anal skin epidermal cells medium

U-2 OS Low U-251 MG Not detected A-549 Not detected CACO-2 Not detected Hep-G2 Not detected HeLa Not detected MCF-7 Not detected PC-3 Not detected RT-4 Not detected A-431 Not detected HEK 293 Not detected

uncertain adrenal gland glandular cells negative appendix glandular cells strong appendix lymphoid tissue negative bone marrow hematopoietic cells moderate breast adipocytes negative breast glandular cells weak breast myoepithelial cells weak bronchus respiratory epithelial cells weak cerebellum cells in granular layer negative cerebellum cells in molecular layer negative cerebellum Purkinje cells negative cerebral cortex endothelial cells negative cerebral cortex glial cells negative cerebral cortex neuronal cells negative cerebral cortex neuropil negative cervix, uterine glandular cells weak cervix, uterine squamous epithelial cells moderate colon endothelial cells negative colon glandular cells weak duodenum glandular cells weak epididymis glandular cells negative esophagus squamous epithelial cells weak fallopian tube glandular cells negative gallbladder glandular cells moderate heart muscle myocytes weak hippocampus glial cells negative hippocampus neuronal cells negative kidney cells in glomeruli negative kidney cells in tubules weak lateral ventricle glial cells negative lateral ventricle neuronal cells negative liver bile duct cells negative liver hepatocytes negative lung macrophages strong lung pneumocytes weak lymph node non-germinal center cells weak nasopharynx respiratory epithelial cells moderate oral mucosa squamous epithelial cells moderate ovary follicle cells negative ovary ovarian stroma cells negative pancreas exocrine glandular cells weak pancreas islets of Langerhans negative parathyroid gland glandular cells weak placenta decidual cells weak placenta trophoblastic cells negative prostate glandular cells moderate rectum glandular cells strong salivary gland glandular cells strong seminal vesicle glandular cells weak skeletal muscle myocytes negative skin fibroblasts moderate skin keratinocytes moderate skin Langerhans moderate skin melanocytes moderate small intestine glandular cells weak smooth muscle smooth muscle cells weak soft tissue 1 adipocytes negative soft tissue 1 chondrocytes moderate soft tissue 1 fibroblasts weak soft tissue 1 peripheral nerve negative soft tissue 2 adipocytes negative soft tissue 2 fibroblasts negative soft tissue 2 peripheral nerve negative spleen cells in red pulp weak spleen cells in white pulp negative stomach, lower glandular cells negative stomach, upper glandular cells negative testis cells in seminiferus ducts negative testis Leydig cells weak thyroid gland glandular cells moderate tonsil germinal center cells moderate tonsil non-germinal center cells moderate tonsil squamous epithelial cells moderate urinary bladder urothelial cells moderate uterus, post-menopause cells in endometrial stroma negative uterus, post-menopause glandular cells negative uterus, pre-menopause cells in endometrial stroma weak uterus, pre-menopause glandular cells moderate vagina squamous epithelial cells moderate vulva/anal skin epidermal cells moderate breast cancer tumor cells strong moderate negative carcinoid tumor cells negative cervical cancer tumor cells strong moderate weak negative colorectal cancer tumor cells strong moderate negative endometrial cancer tumor cells strong moderate weak negative glioma tumor cells moderate negative head and neck cancer tumor cells moderate liver cancer tumor cells strong moderate weak negative lung cancer tumor cells strong moderate weak negative lymphoma tumor cells moderate weak negative melanoma tumor cells strong moderate weak negative ovarian cancer tumor cells moderate weak negative pancreatic cancer tumor cells strong weak negative prostate cancer tumor cells moderate weak negative renal cancer tumor cells weak negative skin cancer tumor cells strong moderate weak negative stomach cancer tumor cells moderate weak negative testis cancer tumor cells negative thyroid cancer tumor cells strong moderate negative urothelial cancer tumor cells strong moderate weak negative non-supportive VKTKEIRQRILRLFHVATHASEP

uncertain adrenal gland glandular cells moderate appendix glandular cells strong appendix lymphoid tissue moderate bone marrow hematopoietic cells moderate breast adipocytes negative breast glandular cells moderate breast myoepithelial cells moderate bronchus respiratory epithelial cells strong cerebellum cells in granular layer negative cerebellum cells in molecular layer moderate cerebellum Purkinje cells strong cerebral cortex endothelial cells negative cerebral cortex glial cells moderate cerebral cortex neuronal cells moderate cerebral cortex neuropil weak cervix, uterine glandular cells moderate cervix, uterine squamous epithelial cells strong colon endothelial cells moderate colon glandular cells strong colon peripheral nerve/ganglion strong duodenum glandular cells strong epididymis glandular cells moderate esophagus squamous epithelial cells strong fallopian tube glandular cells strong gallbladder glandular cells moderate heart muscle myocytes weak hippocampus glial cells strong hippocampus neuronal cells strong kidney cells in glomeruli moderate kidney cells in tubules moderate lateral ventricle glial cells negative lateral ventricle neuronal cells strong liver bile duct cells negative liver hepatocytes moderate lung macrophages moderate lung pneumocytes negative lymph node germinal center cells moderate lymph node non-germinal center cells moderate nasopharynx respiratory epithelial cells strong oral mucosa squamous epithelial cells strong ovary follicle cells negative ovary ovarian stroma cells negative pancreas exocrine glandular cells strong pancreas islets of Langerhans moderate parathyroid gland glandular cells moderate placenta decidual cells moderate placenta trophoblastic cells moderate prostate glandular cells moderate rectum glandular cells strong salivary gland glandular cells strong seminal vesicle glandular cells moderate skeletal muscle myocytes negative skin fibroblasts moderate skin keratinocytes moderate skin Langerhans strong skin melanocytes moderate small intestine glandular cells strong smooth muscle smooth muscle cells moderate soft tissue 1 adipocytes negative soft tissue 1 chondrocytes moderate soft tissue 1 fibroblasts negative soft tissue 2 adipocytes negative soft tissue 2 fibroblasts negative soft tissue 2 peripheral nerve negative spleen cells in red pulp negative spleen cells in white pulp negative stomach, lower glandular cells strong stomach, upper glandular cells strong testis cells in seminiferus ducts strong testis Leydig cells moderate thyroid gland glandular cells moderate tonsil germinal center cells moderate tonsil non-germinal center cells moderate tonsil squamous epithelial cells strong urinary bladder urothelial cells moderate uterus, post-menopause cells in endometrial stroma moderate uterus, post-menopause glandular cells strong uterus, pre-menopause cells in endometrial stroma negative uterus, pre-menopause glandular cells strong vagina squamous epithelial cells strong vulva/anal skin epidermal cells strong breast cancer tumor cells strong moderate carcinoid tumor cells strong moderate weak cervical cancer tumor cells strong moderate colorectal cancer tumor cells strong moderate endometrial cancer tumor cells strong glioma tumor cells strong moderate weak head and neck cancer tumor cells strong moderate liver cancer tumor cells strong moderate lung cancer tumor cells strong moderate lymphoma tumor cells strong moderate weak melanoma tumor cells strong moderate ovarian cancer tumor cells strong moderate pancreatic cancer tumor cells strong moderate prostate cancer tumor cells strong moderate weak negative renal cancer tumor cells moderate negative skin cancer tumor cells strong moderate stomach cancer tumor cells strong moderate testis cancer tumor cells strong moderate thyroid cancer tumor cells moderate urothelial cancer tumor cells strong moderate uncertain supportive OR5A2

very low adrenal gland glandular cells medium appendix glandular cells medium appendix lymphoid tissue none bone marrow hematopoietic cells low breast adipocytes none breast glandular cells low breast myoepithelial cells medium bronchus respiratory epithelial cells medium cerebellum cells in granular layer none cerebellum cells in molecular layer none cerebellum Purkinje cells none cerebral cortex endothelial cells medium cerebral cortex glial cells none cerebral cortex neuronal cells none cerebral cortex neuropil none cervix, uterine glandular cells high cervix, uterine squamous epithelial cells high colon endothelial cells high colon glandular cells medium colon peripheral nerve/ganglion low duodenum glandular cells none epididymis glandular cells high esophagus squamous epithelial cells medium fallopian tube glandular cells medium gallbladder glandular cells medium heart muscle myocytes none hippocampus glial cells none hippocampus neuronal cells none kidney cells in glomeruli high kidney cells in tubules low lateral ventricle glial cells none lateral ventricle neuronal cells none liver bile duct cells none liver hepatocytes none lung macrophages none lung pneumocytes low lymph node germinal center cells none lymph node non-germinal center cells low nasopharynx respiratory epithelial cells high oral mucosa squamous epithelial cells medium ovary follicle cells low ovary ovarian stroma cells none pancreas exocrine glandular cells high pancreas islets of Langerhans none parathyroid gland glandular cells low placenta decidual cells none placenta trophoblastic cells none prostate glandular cells medium rectum glandular cells none salivary gland glandular cells medium seminal vesicle glandular cells low skeletal muscle myocytes none skin fibroblasts none skin keratinocytes medium skin Langerhans medium skin melanocytes none small intestine glandular cells medium smooth muscle smooth muscle cells medium soft tissue 1 adipocytes none soft tissue 1 chondrocytes none soft tissue 1 fibroblasts none soft tissue 1 peripheral nerve none soft tissue 2 adipocytes none soft tissue 2 chondrocytes none soft tissue 2 fibroblasts none soft tissue 2 peripheral nerve none spleen cells in red pulp none spleen cells in white pulp none stomach, lower glandular cells high stomach, upper glandular cells high testis cells in seminiferus ducts medium testis Leydig cells medium thyroid gland glandular cells medium tonsil germinal center cells none tonsil non-germinal center cells none tonsil squamous epithelial cells none urinary bladder urothelial cells medium uterus, post-menopause cells in endometrial stroma none uterus, post-menopause glandular cells high uterus, pre-menopause cells in endometrial stroma none uterus, pre-menopause glandular cells high vagina squamous epithelial cells medium vulva/anal skin epidermal cells medium

U-251 MG Not detected A-549 Not detected CACO-2 Not detected Hep-G2 Not detected HeLa Not detected MCF-7 Not detected PC-3 Not detected RT-4 Not detected A-431 Not detected U-2 OS Not detected HEK 293 Not detected NAMRKAMERDPGISHGGPFI

uncertain adrenal gland glandular cells strong appendix glandular cells moderate appendix lymphoid tissue negative bone marrow hematopoietic cells moderate breast adipocytes negative breast glandular cells moderate breast myoepithelial cells moderate bronchus respiratory epithelial cells moderate cerebellum cells in granular layer moderate cerebellum cells in molecular layer weak cerebellum Purkinje cells strong cerebral cortex endothelial cells weak cerebral cortex glial cells moderate cerebral cortex neuronal cells moderate cerebral cortex neuropil weak cervix, uterine glandular cells moderate cervix, uterine squamous epithelial cells moderate colon endothelial cells moderate colon glandular cells moderate colon peripheral nerve/ganglion moderate duodenum glandular cells strong epididymis glandular cells strong esophagus squamous epithelial cells moderate fallopian tube glandular cells moderate gallbladder glandular cells strong heart muscle myocytes moderate hippocampus glial cells negative hippocampus neuronal cells weak kidney cells in glomeruli weak kidney cells in tubules strong lateral ventricle glial cells weak lateral ventricle neuronal cells moderate liver bile duct cells weak liver hepatocytes strong lung macrophages moderate lung pneumocytes weak lymph node germinal center cells weak lymph node non-germinal center cells strong oral mucosa squamous epithelial cells moderate ovary follicle cells moderate ovary ovarian stroma cells weak pancreas exocrine glandular cells strong pancreas islets of Langerhans moderate parathyroid gland glandular cells weak placenta decidual cells moderate placenta trophoblastic cells moderate prostate glandular cells moderate rectum glandular cells moderate salivary gland glandular cells moderate seminal vesicle glandular cells moderate skeletal muscle myocytes moderate skin fibroblasts weak skin keratinocytes moderate skin Langerhans weak skin melanocytes moderate small intestine glandular cells moderate smooth muscle smooth muscle cells weak soft tissue 1 adipocytes negative soft tissue 1 fibroblasts weak soft tissue 1 peripheral nerve negative soft tissue 2 adipocytes negative soft tissue 2 fibroblasts negative soft tissue 2 peripheral nerve negative spleen cells in red pulp negative spleen cells in white pulp weak stomach, lower glandular cells strong stomach, upper glandular cells strong testis cells in seminiferus ducts strong testis Leydig cells moderate thyroid gland glandular cells moderate tonsil germinal center cells weak tonsil non-germinal center cells weak tonsil squamous epithelial cells weak urinary bladder urothelial cells moderate uterus, post-menopause cells in endometrial stroma negative uterus, post-menopause glandular cells moderate uterus, pre-menopause cells in endometrial stroma negative uterus, pre-menopause glandular cells moderate vagina squamous epithelial cells moderate vulva/anal skin epidermal cells moderate breast cancer tumor cells strong moderate carcinoid tumor cells strong moderate cervical cancer tumor cells moderate weak negative colorectal cancer tumor cells strong moderate endometrial cancer tumor cells moderate weak glioma tumor cells moderate weak head and neck cancer tumor cells moderate weak liver cancer tumor cells strong moderate lung cancer tumor cells strong moderate weak lymphoma tumor cells moderate weak melanoma tumor cells strong moderate ovarian cancer tumor cells strong moderate pancreatic cancer tumor cells strong moderate weak prostate cancer tumor cells strong moderate renal cancer tumor cells moderate weak skin cancer tumor cells moderate weak negative stomach cancer tumor cells strong moderate testis cancer tumor cells strong moderate weak thyroid cancer tumor cells moderate urothelial cancer tumor cells moderate weak uncertain supportive IETYSVYQHDFCGPYMINHF

uncertain adrenal gland glandular cells moderate appendix glandular cells moderate bone marrow hematopoietic cells weak breast adipocytes negative breast glandular cells weak breast myoepithelial cells moderate bronchus respiratory epithelial cells moderate cerebellum cells in granular layer negative cerebellum cells in molecular layer negative cerebellum Purkinje cells negative cerebral cortex endothelial cells moderate cerebral cortex glial cells negative cerebral cortex neuronal cells negative cerebral cortex neuropil negative cervix, uterine glandular cells strong cervix, uterine squamous epithelial cells strong colon endothelial cells strong colon glandular cells moderate duodenum glandular cells negative epididymis glandular cells strong esophagus squamous epithelial cells moderate fallopian tube glandular cells moderate gallbladder glandular cells moderate heart muscle myocytes negative hippocampus glial cells negative hippocampus neuronal cells negative kidney cells in glomeruli strong kidney cells in tubules weak lateral ventricle glial cells negative lateral ventricle neuronal cells negative liver bile duct cells negative liver hepatocytes negative lung macrophages negative lung pneumocytes weak nasopharynx respiratory epithelial cells strong oral mucosa squamous epithelial cells moderate ovary ovarian stroma cells negative pancreas exocrine glandular cells strong pancreas islets of Langerhans negative placenta trophoblastic cells negative prostate glandular cells moderate rectum glandular cells negative salivary gland glandular cells moderate seminal vesicle glandular cells weak skeletal muscle myocytes negative skin fibroblasts negative skin keratinocytes moderate skin Langerhans moderate skin melanocytes negative small intestine glandular cells moderate smooth muscle smooth muscle cells strong soft tissue 1 chondrocytes negative soft tissue 1 fibroblasts negative soft tissue 1 peripheral nerve negative soft tissue 2 chondrocytes negative soft tissue 2 fibroblasts negative spleen cells in red pulp negative spleen cells in white pulp negative stomach, lower glandular cells strong stomach, upper glandular cells strong testis cells in seminiferus ducts moderate testis Leydig cells moderate thyroid gland glandular cells moderate tonsil germinal center cells negative tonsil non-germinal center cells negative tonsil squamous epithelial cells negative urinary bladder urothelial cells moderate uterus, post-menopause cells in endometrial stroma negative uterus, post-menopause glandular cells strong uterus, pre-menopause cells in endometrial stroma negative uterus, pre-menopause glandular cells strong vagina squamous epithelial cells moderate vulva/anal skin epidermal cells moderate breast cancer tumor cells moderate negative carcinoid tumor cells weak negative cervical cancer tumor cells strong moderate weak negative colorectal cancer tumor cells strong moderate weak negative endometrial cancer tumor cells strong moderate weak negative glioma tumor cells moderate weak negative head and neck cancer tumor cells moderate negative liver cancer tumor cells moderate weak negative lung cancer tumor cells moderate weak negative lymphoma tumor cells moderate weak negative melanoma tumor cells strong moderate weak negative ovarian cancer tumor cells moderate weak negative pancreatic cancer tumor cells moderate weak negative prostate cancer tumor cells weak negative renal cancer tumor cells weak negative skin cancer tumor cells strong moderate weak negative stomach cancer tumor cells strong moderate weak negative testis cancer tumor cells strong moderate negative thyroid cancer tumor cells moderate weak urothelial cancer tumor cells moderate weak negative uncertain uncertain Copyrighted by the Human Protein Atlas, http://www.proteinatlas.org/about