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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
High
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
143.4
nTPM
HPA:
143.4
nTPM
GTEx:
71.7
nTPM
FANTOM5:
307.0
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA029159
Antibody HPA029160
Antibody CAB000108
Antibody CAB001950
Cholangiocytes
High
High
High
Not detected
Hepatocytes
High
High
Medium
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
143.4
Female, age 60
Liver sample 21 nTPM: 134
Male, age 54
Liver sample 23 nTPM: 132.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 156.3
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 172.2
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 143.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 133.6
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 154.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 113.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 121.2
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 173
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
71.7
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 71.7
Samples: 226
Max nTPM: 280.8
Min nTPM: 44.2
Std nTPM: 18.5
Median nTPM: 69.7
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
280.8
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
104.5
GTEX-R53T-0326-SM-48FEC
50-59 years, female
104.1
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
103.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
100.8
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
100.0
GTEX-18A7A-1526-SM-72D69
50-59 years, female
99.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
99.1
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
98.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
97.4
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
97.2
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
96.8
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
95.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
95.1
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
94.7
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
92.9
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
91.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
90.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
90.2
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
90.1
GTEX-14JG1-1626-SM-664NH
40-49 years, male
89.7
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
89.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
88.9
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
88.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
88.4
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
87.5
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
86.8
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
85.7
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
85.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
85.0
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
84.8
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
84.2
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
84.2
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
82.9
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
82.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
82.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
82.4
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
82.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
82.2
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
81.9
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
81.7
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
81.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
81.3
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
81.2
GTEX-17F96-1226-SM-79OK2
70-79 years, male
80.9
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
80.5
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
80.2
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
80.0
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
79.9
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
79.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
79.5
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
79.1
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
78.6
GTEX-14E7W-1526-SM-6871X
70-79 years, male
78.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
78.5
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
78.5
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
78.0
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
77.9
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
77.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
77.8
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
77.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
76.9
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
76.2
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
76.1
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
76.1
GTEX-QEL4-1226-SM-447A4
50-59 years, male
75.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
75.6
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
75.5
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
75.2
GTEX-1B933-1226-SM-731DW
50-59 years, female
74.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
74.8
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
74.8
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
74.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
74.7
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
74.7
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
74.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
74.5
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
74.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
74.4
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
74.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
73.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
73.8
GTEX-X261-1726-SM-4PQYT
50-59 years, male
73.8
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
73.8
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
73.6
GTEX-13112-1426-SM-5EGH8
50-59 years, male
73.5
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
73.5
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
73.4
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
73.1
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
73.1
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
73.0
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
72.9
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
72.5
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
72.5
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
72.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
71.8
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
71.6
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
71.5
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
71.4
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
71.2
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
71.1
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
70.8
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
70.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
70.8
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
70.7
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
70.5
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
70.5
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
70.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
70.3
GTEX-144GL-1426-SM-79OMA
50-59 years, male
70.2
GTEX-P78B-1326-SM-3P611
40-49 years, female
70.2
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
69.9
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
69.8
GTEX-QESD-2026-SM-447BI
20-29 years, male
69.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
69.6
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
69.4
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
69.1
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
69.1
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
69.1
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
69.0
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
68.7
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
68.7
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
68.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
68.5
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
68.3
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
68.2
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
67.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
67.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
67.5
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
67.3
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
67.2
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
66.9
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
66.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
66.8
GTEX-18A66-2026-SM-7189C
60-69 years, male
66.7
GTEX-S33H-1626-SM-4AD68
30-39 years, male
66.3
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
66.2
GTEX-S32W-1926-SM-4AD63
50-59 years, female
65.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
65.6
GTEX-11ZUS-2526-SM-59872
30-39 years, male
65.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
65.4
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
65.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
65.3
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
65.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
65.0
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
65.0
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
64.8
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
64.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
64.7
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
64.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
64.4
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
64.3
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
64.1
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
64.0
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
63.9
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
63.8
GTEX-12696-0826-SM-5EGGE
60-69 years, male
63.6
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
63.4
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
63.4
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
63.0
GTEX-14PJO-1726-SM-68719
60-69 years, male
63.0
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
62.9
GTEX-13113-1326-SM-5GCOI
60-69 years, female
62.8
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
62.7
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
62.7
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
62.5
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
62.4
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
62.3
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
61.9
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
61.9
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
61.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
61.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
61.7
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
61.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
61.4
GTEX-REY6-1226-SM-48FDR
60-69 years, male
61.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
61.4
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
61.4
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
61.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
61.1
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
60.9
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
60.8
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
60.4
GTEX-1B932-1426-SM-793AN
40-49 years, female
59.9
GTEX-YECK-1926-SM-4W21H
60-69 years, male
59.7
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
59.5
GTEX-RN64-1826-SM-48FDV
50-59 years, male
59.3
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
59.1
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
59.0
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
58.9
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
58.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
58.6
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
58.6
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
58.5
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
58.4
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
57.9
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
57.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
57.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
57.5
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
56.7
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
56.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
55.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
55.8
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
55.6
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
55.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
55.3
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
55.3
GTEX-RU72-1426-SM-46MUF
50-59 years, female
55.2
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
55.2
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
54.9
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
54.9
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
54.3
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
54.1
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
52.8
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
52.5
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
52.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
52.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
51.8
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
51.8
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
51.6
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
51.2
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
48.9
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
47.9
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
47.8
GTEX-11GSP-0626-SM-5986T
60-69 years, female
45.9
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
44.2
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
