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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
96.2
nTPM
HPA:
96.2
nTPM
GTEx:
92.5
nTPM
FANTOM5:
129.7
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA062101
Cholangiocytes
Not detected
Hepatocytes
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
96.2
Female, age 60
Liver sample 21 nTPM: 79.8
Male, age 54
Liver sample 23 nTPM: 91.4
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 117
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 135.5
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 122.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 92.9
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 86.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 86.3
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 84.3
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 65.9
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
92.5
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 92.5
Samples: 226
Max nTPM: 589.5
Min nTPM: 11.9
Std nTPM: 75.0
Median nTPM: 64.5
GTEX-REY6-1226-SM-48FDR
60-69 years, male
589.5
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
446.8
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
377.3
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
344.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
340.9
GTEX-14PJO-1726-SM-68719
60-69 years, male
302.9
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
299.1
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
286.2
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
259.3
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
256.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
253.2
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
240.7
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
216.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
215.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
205.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
202.5
GTEX-QEL4-1226-SM-447A4
50-59 years, male
195.6
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
188.0
GTEX-X261-1726-SM-4PQYT
50-59 years, male
187.9
GTEX-13113-1326-SM-5GCOI
60-69 years, female
183.4
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
174.1
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
174.0
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
167.4
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
161.2
GTEX-18A66-2026-SM-7189C
60-69 years, male
160.5
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
160.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
154.5
GTEX-S33H-1626-SM-4AD68
30-39 years, male
151.0
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
149.3
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
148.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
148.7
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
148.4
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
147.2
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
144.6
GTEX-RU72-1426-SM-46MUF
50-59 years, female
140.9
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
140.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
140.1
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
139.1
GTEX-1B932-1426-SM-793AN
40-49 years, female
138.9
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
138.5
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
138.2
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
135.9
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
134.6
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
130.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
130.7
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
130.0
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
128.1
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
128.0
GTEX-14XAO-0226-SM-68728
60-69 years, female
127.3
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
126.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
126.4
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
124.9
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
124.7
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
123.8
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
122.6
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
120.6
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
120.5
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
119.6
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
118.0
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
117.8
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
116.0
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
115.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
113.5
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
113.1
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
112.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
112.2
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
109.1
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
108.0
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
106.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
105.6
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
105.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
103.8
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
103.5
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
100.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
98.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
91.6
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
91.2
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
91.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
90.7
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
89.8
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
88.3
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
84.9
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
84.5
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
83.3
GTEX-P78B-1326-SM-3P611
40-49 years, female
83.3
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
83.3
GTEX-17F96-1226-SM-79OK2
70-79 years, male
82.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
81.6
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
81.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
79.6
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
79.6
GTEX-18A7A-1526-SM-72D69
50-59 years, female
78.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
78.4
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
77.8
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
77.8
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
76.8
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
74.9
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
74.5
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
74.0
GTEX-17HHE-0126-SM-79398
50-59 years, male
73.8
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
72.7
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
72.5
GTEX-1399T-0826-SM-5IFES
60-69 years, male
71.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
71.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
71.5
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
70.2
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
68.8
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
67.6
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
67.5
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
66.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
66.4
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
65.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
65.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
63.9
GTEX-14PHX-0526-SM-664NW
50-59 years, male
63.8
GTEX-S32W-1926-SM-4AD63
50-59 years, female
63.5
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
63.4
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
63.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
62.9
GTEX-14JG1-1626-SM-664NH
40-49 years, male
62.0
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
61.8
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
61.7
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
61.5
GTEX-YECK-1926-SM-4W21H
60-69 years, male
60.9
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
60.8
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
60.7
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
60.5
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
59.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
59.5
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
59.2
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
58.8
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
58.4
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
58.1
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
58.0
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
57.8
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
57.2
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
57.1
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
56.8
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
56.2
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
56.2
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
56.2
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
55.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
55.5
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
55.2
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
54.8
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
54.7
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
54.0
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
53.6
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
53.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
52.9
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
52.6
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
52.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
52.0
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
51.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
51.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
51.3
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
50.7
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
50.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
50.2
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
49.7
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
49.5
GTEX-14E7W-1526-SM-6871X
70-79 years, male
49.4
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
48.8
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
48.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
47.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
47.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
47.8
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
47.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
47.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
47.1
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
47.0
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
46.9
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
46.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
46.4
GTEX-11GSP-0626-SM-5986T
60-69 years, female
45.4
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
45.2
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
44.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
43.9
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
43.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
43.5
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
43.2
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
43.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
42.8
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
42.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
42.7
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
42.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
42.3
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
41.3
GTEX-13112-1426-SM-5EGH8
50-59 years, male
40.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
39.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
39.6
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
39.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
39.0
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
38.9
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
37.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
36.6
GTEX-11ZUS-2526-SM-59872
30-39 years, male
36.1
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
36.1
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
36.0
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
35.9
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
35.7
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
34.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
34.5
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
34.2
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
33.9
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
33.6
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
33.4
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
33.4
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
33.0
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
32.4
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
32.2
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
32.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
31.9
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
31.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
30.2
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
30.2
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
29.5
GTEX-RN64-1826-SM-48FDV
50-59 years, male
29.4
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
29.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
27.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
25.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
24.1
GTEX-144GL-1426-SM-79OMA
50-59 years, male
22.6
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
16.9
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
16.6
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
11.9
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
