Proteins detected in plasma using proximity extension assay
Proximity extension assays (PEA) based on Olink was performed for 748 proteins based on a longitudinal wellness study covering 86 individuals with four visits during one year at three months intervals. The results are presented as Normalized Protein Expression (NPX) for the individual genes corresponding to these proteins for all females and males respectively.
Below is a summary of the variation between individuals and within individuals for these 748 proteins calculated as the mean standard variation (SD) for each protein within each visit and across all analyzed individuals (n=86), and as the mean SD for each protein within each individual across all visits (n=4), respectively.
Figure 1 Protein profiles of Leptin shown with the individual concentrations across four visits with three months interval and the median levels for males and females, respectively.
Figure 2 A summary of the results for females and males as "violin" plots showing the distribution of protein levels of Leptin across the individuals for each visit. These plots are shown for all the 748 proteins on respective gene page accessed though the links in the Table above.