Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nCPM"	"RNA single cell type group specificity"	"RNA single cell type group distribution"	"RNA single cell type group specificity score"	"RNA single cell type group specific nCPM"	"RNA single nuclei brain specificity"	"RNA single nuclei brain distribution"	"RNA single nuclei brain specificity score"	"RNA single nuclei brain specific nCPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific pTPM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	"Protein cell type specificity"	"Protein cell type distribution"	"Protein cell type specificity score"	"Protein cell type specific Intensity"	"Protein tissue specificity"	"Protein tissue distribution"	"Protein tissue specificity score"	"Protein tissue specific Intensity"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"Secretome function"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Brain expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	Interactions	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)"	"Cancer prognostics - Breast Invasive Carcinoma (TCGA)"	"Cancer prognostics - Breast Invasive Carcinoma (validation)"	"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)"	"Cancer prognostics - Colon Adenocarcinoma (TCGA)"	"Cancer prognostics - Colon Adenocarcinoma (validation)"	"Cancer prognostics - Glioblastoma Multiforme (TCGA)"	"Cancer prognostics - Glioblastoma Multiforme (validation)"	"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)"	"Cancer prognostics - Kidney Chromophobe (TCGA)"	"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)"	"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)"	"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)"	"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)"	"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)"	"Cancer prognostics - Lung Adenocarcinoma (TCGA)"	"Cancer prognostics - Lung Adenocarcinoma (validation)"	"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)"	"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)"	"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)"	"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)"	"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)"	"Cancer prognostics - Pancreatic Adenocarcinoma (validation)"	"Cancer prognostics - Prostate Adenocarcinoma (TCGA)"	"Cancer prognostics - Rectum Adenocarcinoma (TCGA)"	"Cancer prognostics - Rectum Adenocarcinoma (validation)"	"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)"	"Cancer prognostics - Stomach Adenocarcinoma (TCGA)"	"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)"	"Cancer prognostics - Thyroid Carcinoma (TCGA)"	"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)"
UNC5A	"KIAA1976, UNC5H1"	ENSG00000113763	"Unc-5 netrin receptor A"	Q6ZN44	5	176810519-176880898	"Predicted membrane proteins"	Apoptosis	"Developmental protein, Receptor"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	4	"brain: 58.7"	"Cell type enhanced"	"Detected in some"		"Adrenal medulla cells: 42.5;Brain excitatory neurons: 55.1;Brain inhibitory neurons: 31.0;Corticotrophs: 22.2;Late spermatids: 11.0;Müller glia: 22.6;Oligodendrocyte progenitor cells: 10.7;Other brain neurons: 21.5;Retinal amacrine cells: 47.4;Retinal horizontal cells: 12.0;Rod photoreceptor cells: 12.1"	"Cell type enhanced"	"Detected in some"		"Adrenal endocrine cells: 42.5;Glial cells: 22.6;Neuronal cells: 55.1;Pituitary endocrine cells: 22.2"	"Low cell type specificity"	"Detected in many"			"Cancer enhanced"	"Detected in many"		"Ovary Serous Cystadenocarcinoma (TCGA): 11.2"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Neuroblastoma: 18.5"	"Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Stomach - Parietal cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"Astrocytes and Neuropil: 428437.7;Microglia and Neuropil: 1289433.0"	"Tissue enriched"	"Detected in single"	213882	"cerebral cortex: 21388232.9"	HPA071450			Approved	"Plasma membrane,Cytosol"			NA	NA				"Cluster 27: Cerebellum - Synaptic function"	"Cluster 53: Neurons - Mixed function"	"Cluster 10: Ciliated cells - Ion channel activity"	"Cluster 35: Neurons - Synaptic function & neurogenesis"	2	"Plasma membrane, Cytosol"		"HPA071450: "		"unprognostic (1.62e-2)"	"unprognostic (4.37e-2)"	"unprognostic (5.48e-2)"			"unprognostic (5.10e-2)"	"potential prognostic favorable (6.55e-4)"				"potential prognostic unfavorable (1.36e-4)"	"unprognostic (3.69e-1)"							"unprognostic (4.99e-2)"	"unprognostic (7.69e-2)"	"unprognostic (3.88e-1)"	"unprognostic (1.64e-2)"	"unprognostic (7.37e-2)"				"unprognostic (1.21e-1)"	"unprognostic (2.95e-1)"		"unprognostic (3.18e-2)"
ADORA2B		ENSG00000170425	"Adenosine A2b receptor"	P29275	17	15945130-15975746	"FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins"		"G-protein coupled receptor, Receptor, Transducer"	"FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"brain: 12.5;urinary bladder: 15.6"	"Cell type enhanced"	"Detected in many"		"Basal keratinocytes: 81.9;Bergmann glia: 41.6;Conjunctival goblet cells: 45.6;Esophageal basal cells: 47.4;Respiratory basal cells: 30.1;Respiratory secretory cells: 34.5;Retinal pigment epithelial cells: 59.7;Suprabasal keratinocytes: 57.3;Urothelial cells: 33.5"	"Cell type enhanced"	"Detected in many"		"Basal cells: 81.9;Pigment cells: 59.7;Suprabasal cells: 57.3"	"Cell type enhanced"	"Detected in many"		"Bergmann glia: 42.2;pericyte: 75.6"	"Low cancer specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 17.3;myeloid DC: 10.5"	"Group enriched"	"Detected in many"	113	"dendritic cells: 10.5;granulocytes: 17.3;monocytes: 5.9"	"Low cancer specificity"	"Detected in many"			"Breast - Breast myoepithelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other)"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected"	"Not detected"			"Not detected"	"Not detected"			HPA073747			Supported	"Vesicles,Plasma membrane,Primary cilium tip"			NA	Yes			"Cluster 26: Monocytes - Plasma membrane proteins"	"Cluster 1: Choroid plexus - Transmembrane transport"	"Cluster 40: Astrocytes - Astrocyte-neuron interactions"	"Cluster 49: HMC-1 - Innate immune response"	"Cluster 26: Keratinocytes - Keratinization"	28	"Plasma membrane"	"Vesicles, Primary cilium tip"	"HPA073747: "	"unprognostic (7.71e-2)"	"unprognostic (7.31e-2)"	"unprognostic (1.90e-2)"	"unprognostic (1.93e-2)"	"unprognostic (1.24e-1)"	"unprognostic (1.65e-2)"	"unprognostic (2.97e-2)"	"unprognostic (1.31e-1)"	"unprognostic (9.21e-3)"		"potential prognostic unfavorable (3.29e-11)"	"unprognostic (1.43e-2)"			"unprognostic (5.82e-2)"	"unprognostic (1.14e-1)"	"unprognostic (8.63e-3)"	"unprognostic (6.40e-2)"	"unprognostic (9.42e-2)"			"unprognostic (1.31e-3)"	"unprognostic (1.98e-2)"		"unprognostic (1.83e-1)"	"unprognostic (5.14e-1)"	"unprognostic (2.00e-1)"	"unprognostic (8.92e-2)"	"unprognostic (3.43e-1)"		"unprognostic (4.79e-2)"
NTN1	"NET1, NTN1L"	ENSG00000065320	"Netrin 1"	O95631	17	9021510-9244000	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins"	Apoptosis		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"blood vessel: 35.5;heart muscle: 56.1"	"Cell type enhanced"	"Detected in many"		"Conjunctival goblet cells: 301.9;Epididymal clear cells: 249.0;Ocular epithelial cells: 218.8;Oligodendrocyte progenitor cells: 251.4;Renal collecting duct intercalated cells: 382.2;Respiratory basal cells: 534.7;Respiratory deuterosomal cells: 353.5;Respiratory ionocytes: 264.2;Respiratory secretory cells: 420.8;Salivary duct cells: 327.7;Smooth muscle cells: 260.8"	"Cell type enhanced"	"Detected in many"		"Basal cells: 534.7;Ductal cells: 382.2;Secretory cells: 420.8"	"Cell type enhanced"	"Detected in many"		"committed oligodendrocyte precursor: 205.6;ependymal cell: 189.7;oligodendrocyte precursor cell: 308.7;vascular associated smooth muscle cell: 205.8"	"Cancer enhanced"	"Detected in many"		"Kidney Chromophobe (TCGA): 39.2"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Rhabdoid: 22.3"	"Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Fibroblasts, Prostate - Prostate basal glandular cells, Skin - Fibroblasts_2, Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in some"	5145	"Fallopian tube cells: 687545.6;Large ducts: 402122.6;Smooth muscle cells: 453748.4"	"Group enriched"	"Detected in some"	23700	"blood vessel: 2376709.9;fallopian tube: 2363319.4"	HPA056419	Approved		Approved	"Nucleoplasm,Actin filaments,Cytosol"	"Secreted to extracellular matrix"	Other	NA	NA		2200000		"Cluster 35: Non-specific - Mixed function"	"Cluster 41: Monoamines - Neurotransmitter signalling"	"Cluster 5: Rhabdoid - Unknown function"	"Cluster 38: Secretory epithelial cells - Exocrine secretion"	4	Cytosol	"Nucleoplasm, Actin filaments"	"HPA056419: "	"unprognostic (5.80e-2)"	"unprognostic (1.38e-1)"	"unprognostic (4.75e-1)"	"unprognostic (8.19e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.36e-1)"	"unprognostic (2.43e-1)"	"unprognostic (1.86e-1)"	"unprognostic (2.27e-3)"	"unprognostic (5.22e-2)"	"unprognostic (3.31e-3)"		"unprognostic (3.41e-2)"	"unprognostic (1.10e-1)"	"unprognostic (1.22e-2)"	"unprognostic (4.45e-1)"	"unprognostic (1.06e-1)"	"unprognostic (6.75e-2)"	"unprognostic (1.45e-1)"	"unprognostic (7.33e-3)"	"unprognostic (3.08e-1)"	"unprognostic (2.80e-1)"	"unprognostic (3.29e-1)"	"unprognostic (8.67e-2)"	"unprognostic (7.47e-2)"	"unprognostic (3.52e-2)"	"unprognostic (9.24e-2)"	"unprognostic (1.07e-2)"	"unprognostic (2.07e-1)"		"unprognostic (1.65e-1)"
UNC5B	"p53RDL1, UNC5H2"	ENSG00000107731	"Unc-5 netrin receptor B"	Q8IZJ1	10	71212570-71302864	"Plasma proteins, Predicted membrane proteins"	"Angiogenesis, Apoptosis"	"Developmental protein, Receptor"		"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Adrenal medulla cells: 117.0;Esophageal apical cells: 73.1;Esophageal suprabasal cells: 90.5;Lymphatic endothelial cells: 72.8;Müller glia: 96.3;Oligodendrocytes: 110.0;Prostatic hillock cells: 130.3;Retinal amacrine cells: 83.0;Retinal horizontal cells: 98.2"	"Cell type enhanced"	"Detected in many"		"Adrenal endocrine cells: 117.0;Barrier epithelial cells: 130.3"	"Cell type enhanced"	"Detected in many"		"oligodendrocyte: 137.4"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Neuroblastoma: 75.9"	"Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Gastric mucous cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Cell type enhanced"	"Detected in some"		"Glomeruli: 922391.5;Microglia and Neuropil: 790318.1;Pancreatic islets: 689185.6"	"Group enriched"	"Detected in some"	2905	"cerebral cortex: 270764.4;lymphoid tissue: 310301.8"	HPA076687	Approved						NA	NA				"Cluster 81: Squamous epithelium - Keratinization"	"Cluster 6: Non-specific - Immune response"	"Cluster 17: Neuroblastoma - Neuronal signaling"	"Cluster 32: Endothelial cells - Angiogenesis & vascular immunity"	5			"HPA076687: "	"unprognostic (7.19e-2)"	"unprognostic (2.45e-2)"	"unprognostic (3.86e-1)"	"unprognostic (3.29e-1)"	"unprognostic (8.34e-2)"	"unprognostic (6.05e-2)"	"unprognostic (6.56e-2)"	"unprognostic (1.27e-1)"	"unprognostic (1.03e-1)"	"potential prognostic unfavorable (8.08e-4)"	"potential prognostic favorable (5.53e-4)"	"unprognostic (3.22e-3)"	"unprognostic (3.19e-2)"	"potential prognostic unfavorable (7.68e-6)"	"unprognostic (3.80e-1)"	"unprognostic (1.12e-1)"	"unprognostic (2.22e-3)"	"unprognostic (2.35e-2)"	"unprognostic (1.50e-1)"	"unprognostic (1.46e-3)"	"unprognostic (6.20e-3)"	"unprognostic (1.86e-2)"	"unprognostic (1.57e-1)"	"unprognostic (7.20e-2)"	"unprognostic (9.99e-2)"	"unprognostic (1.68e-2)"	"unprognostic (2.19e-3)"	"unprognostic (1.60e-1)"	"unprognostic (1.60e-1)"	"unprognostic (6.00e-2)"	"unprognostic (7.45e-3)"