Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1212.9;lung: 1626.5" "Cell type enhanced" "Detected in many" "Adipocytes: 1247.2;Cardiomyocytes: 393.1;Endothelial cells: 861.7;Hepatocytes: 654.0;Microglial cells: 339.1;Smooth muscle cells: 471.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Cancer enhanced" "Detected in many" "Brain cancer: 48.1;liver cancer: 106.6;skin cancer: 72.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Macrophages, Kidney - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" "Enzyme inhibitor" NA NA 1630000000000 170000000000 "Cluster 1: T-cells - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 47: Endothelial cells - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 51 "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" ABLIM3 KIAA0843 ENSG00000173210 "Actin binding LIM protein family member 3" O94929 5 149141483-149260542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 112.9" "Cell type enhanced" "Detected in many" "Adipocytes: 178.0;Cardiomyocytes: 69.1;Hepatocytes: 94.1;Oligodendrocyte precursor cells: 59.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 43.8" "Adipose visceral - Endothelial cells, Kidney - Proximal tubular cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003245 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 30000 "Cluster 4: Neutrophils - Degranulation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Nucleoplasm, Plasma membrane" "Cell Junctions" "HPA003245: AB_1078083" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (9.87e-2)" "unprognostic (1.75e-1)" "unprognostic (8.74e-2)" "unprognostic (4.19e-2)" "unprognostic (9.48e-3)" "unprognostic (4.37e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.12e-2)" "unprognostic (8.10e-2)" "unprognostic (2.45e-3)" "unprognostic (1.20e-1)" ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.3;placenta: 19.9" "Cell type enhanced" "Detected in some" "Adipocytes: 35.8;Muller glia cells: 10.3;Oligodendrocytes: 15.6;Oocytes: 15.4;Rod photoreceptor cells: 8.3;Serous glandular cells: 8.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "liver cancer: 2.6;testis cancer: 9.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Enzyme Yes NA "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" "Midbody, Mitotic spindle" "HPA044326: AB_10961006" "unprognostic (1.10e-2)" "unprognostic (2.78e-1)" "unprognostic (1.38e-1)" "unprognostic (2.50e-1)" "unprognostic (8.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.98e-1)" "unprognostic (4.11e-2)" "unprognostic (2.20e-2)" "unprognostic (8.17e-4)" "unprognostic (1.77e-5)" "unprognostic (2.17e-1)" "unprognostic (3.41e-1)" "unprognostic (2.47e-4)" ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 82.3;Endothelial cells: 73.9;Lymphatic endothelial cells: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005070, HPA048344" Approved NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 102.7" "Cell type enhanced" "Detected in many" "Adipocytes: 393.9;Alveolar cells type 1: 205.3;Alveolar cells type 2: 303.0;Endothelial cells: 214.3;Microglial cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 11.7;pancreatic cancer: 6.7;Sarcoma: 6.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 209.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 220.3;Melanocytes: 140.9;NK-cells: 180.6;Syncytiotrophoblasts: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.5" "Lineage enriched" "Detected in many" 5 "T-cells: 160.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Prostate basal glandular cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" Receptor NA NA 32000 "Cluster 24: Non-specific - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 19: NK-cells - Adaptive immune response" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.8" "Group enriched" "Detected in many" 6 "Adipocytes: 559.4;Endothelial cells: 298.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 12.2;thyroid cancer: 15.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 118.6" "Cell type enhanced" "Detected in some" "Hepatocytes: 74.4;Oligodendrocyte precursor cells: 31.6;Oligodendrocytes: 35.8;Oocytes: 103.7;Proximal enterocytes: 25.5" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.4" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.2" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 43: Hepatocytes - Metabolism" 1 Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 199.6" "Group enriched" "Detected in some" 4 "Late spermatids: 285.2;Microglial cells: 136.9;Rod photoreceptor cells: 183.3" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cancer enhanced" "Detected in many" "cervical cancer: 7.6" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Late spermatids" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Retina - Visual perception" "Cluster 47: Endothelial cells - Vasculature" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" ARAP3 "CENTD3, DRAG1, FLJ21065" ENSG00000120318 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" Q8WWN8 5 141653401-141682230 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 31.1;Endothelial cells: 29.7;Horizontal cells: 15.7;Lymphatic endothelial cells: 26.4;Microglial cells: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.3;neutrophil: 2.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042887 Uncertain NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 1 "HPA042887: AB_10796681" "unprognostic (1.98e-1)" "unprognostic (4.88e-2)" "unprognostic (9.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.58e-2)" "unprognostic (5.26e-2)" "unprognostic (3.77e-3)" "unprognostic (9.76e-2)" "unprognostic (3.43e-2)" "unprognostic (1.39e-1)" "unprognostic (4.42e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (4.96e-2)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.2;breast: 40.2" "Cell type enhanced" "Detected in some" "Adipocytes: 62.0;Endothelial cells: 46.6;Lymphatic endothelial cells: 13.9;Microglial cells: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Sarcoma: 1.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" ARL15 "ARFRP2, FLJ20051" ENSG00000185305 "ADP ribosylation factor like GTPase 15" Q9NXU5 5 53883942-54310582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 427.4;Inhibitory neurons: 273.2;Microglial cells: 390.1;Oligodendrocyte precursor cells: 173.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Endothelial cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044604, HPA063820" Uncertain Approved "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 34: Neurons - Neuronal signaling" 2 "Golgi apparatus" "Plasma membrane, Cell Junctions" "HPA044604: AB_10960542, HPA063820: AB_2685131" "unprognostic (2.18e-1)" "unprognostic (4.32e-2)" "unprognostic (1.82e-2)" "unprognostic (2.41e-2)" "unprognostic (1.08e-1)" "unprognostic (3.70e-1)" "unprognostic (8.52e-3)" "unprognostic (1.16e-2)" "unprognostic (3.05e-2)" "unprognostic (6.56e-2)" "unprognostic (4.26e-3)" "unprognostic (3.86e-1)" "unprognostic (2.48e-3)" "unprognostic (1.35e-1)" "unprognostic (9.15e-2)" "unprognostic (5.60e-2)" "unprognostic (1.08e-1)" ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 334.1;Late spermatids: 474.7;Oligodendrocyte precursor cells: 583.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.7" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.7;monocytes: 6.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Uncertain "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 76: Oligodendrocyte precursor - Unknown function" 11 Centrosome "Plasma membrane, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" ATP6V1C2 "ATP6C2, VMA5" ENSG00000143882 "ATPase H+ transporting V1 subunit C2" Q8NEY4 2 10721100-10785110 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 78.4;salivary gland: 100.1;skin 1: 85.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 148.0;Distal tubular cells: 52.2;Glandular and luminal cells: 69.8;Oocytes: 55.1;Salivary duct cells: 82.7;Syncytiotrophoblasts: 173.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Kidney - Intercalated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034734, HPA067305" Approved Uncertain Mitochondria NA NA "Cluster 13: Skin - Cornification" "Cluster 34: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" Mitochondria "HPA034734: AB_2674305, HPA067305: AB_2732763" "unprognostic (2.29e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-2)" "unprognostic (6.55e-3)" "unprognostic (2.69e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-3)" "unprognostic (8.53e-2)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" "unprognostic (6.77e-2)" "unprognostic (2.73e-2)" "prognostic unfavorable (1.12e-11)" "unprognostic (6.17e-2)" "unprognostic (3.30e-1)" "unprognostic (2.37e-1)" "unprognostic (8.27e-2)" AVPR2 "DIR, DIR3, V2R" ENSG00000126895 "Arginine vasopressin receptor 2" P30518 X 153902531-153907166 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes insipidus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.6;kidney: 10.7" "Group enriched" "Detected in some" 7 "Adipocytes: 46.0;Collecting duct cells: 40.8;Endothelial cells: 17.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 9.3" "Group enriched" "Detected in some" 28 "intermediate monocyte: 3.5;non-classical monocyte: 3.2" "Lineage enriched" "Detected in single" 30 "monocytes: 3.5" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 5.3" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 29 "cerebellum: 10.5" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 70: DU4475 - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "unprognostic (3.05e-2)" "unprognostic (5.62e-2)" "unprognostic (1.99e-4)" "unprognostic (2.50e-4)" "unprognostic (2.76e-1)" "unprognostic (7.10e-6)" "unprognostic (3.80e-3)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-2)" "unprognostic (4.21e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-2)" "unprognostic (1.87e-1)" "unprognostic (4.38e-1)" "unprognostic (9.83e-2)" BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 273.9" "Cell type enhanced" "Detected in many" "Adipocytes: 66.9;Astrocytes: 187.9;Excitatory neurons: 126.8;Inhibitory neurons: 59.6;Muller glia cells: 114.8;Oligodendrocyte precursor cells: 117.9" "Cancer enriched" "Detected in many" 8 "glioma: 139.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 14: Non-specific - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" Cytosol Nucleoplasm "HPA027132: AB_10600985, HPA068307: AB_2685971" "unprognostic (1.68e-1)" "unprognostic (9.17e-3)" "unprognostic (1.40e-2)" "unprognostic (4.62e-4)" "unprognostic (1.75e-2)" "unprognostic (2.84e-2)" "unprognostic (1.39e-1)" "unprognostic (7.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.99e-2)" "unprognostic (4.17e-2)" "unprognostic (2.18e-2)" "unprognostic (7.58e-2)" "unprognostic (2.51e-3)" "unprognostic (2.76e-2)" "unprognostic (1.70e-1)" "unprognostic (9.27e-3)" BCAP29 "BAP29, DKFZp686M2086" ENSG00000075790 "B cell receptor associated protein 29" Q9UHQ4 7 107580246-107629170 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 50.0;Excitatory neurons: 78.4;Inhibitory neurons: 68.3;Oligodendrocyte precursor cells: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029215, HPA049694" Supported Approved Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" Cytosol "HPA029215: AB_10602331, HPA049694: AB_2680854" "unprognostic (3.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.82e-2)" "unprognostic (1.05e-2)" "unprognostic (5.42e-3)" "unprognostic (4.71e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.43e-2)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (2.31e-2)" "unprognostic (7.36e-2)" "unprognostic (8.34e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-2)" "unprognostic (5.28e-3)" "unprognostic (1.81e-1)" BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 34.3;Endothelial cells: 35.2;Lymphatic endothelial cells: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.3;ovarian cancer: 3.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 19.7" "Cell type enhanced" "Detected in some" "Adipocytes: 42.9;Endothelial cells: 21.6;Inhibitory neurons: 21.7;Microglial cells: 70.7;Oocytes: 110.3;Plasma cells: 30.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "Myeloma: 42.2;Rhabdoid: 30.5" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Skin - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002773, HPA062683" Approved Uncertain Mitochondria "Secreted to blood" Cytokine No No 4970000 46000 "Cluster 46: Basophils - Proteolysis" "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Mitochondria "CAB002773: , HPA062683: AB_2684832" "prognostic favorable (6.45e-4)" "unprognostic (2.99e-1)" "unprognostic (4.20e-1)" "unprognostic (6.71e-2)" "unprognostic (2.44e-1)" "unprognostic (7.27e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.94e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.29e-2)" "unprognostic (2.95e-1)" "unprognostic (2.29e-3)" BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 174.0;Excitatory neurons: 195.3;Inhibitory neurons: 182.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" BTNL9 "BTN8, FLJ32535" ENSG00000165810 "Butyrophilin like 9" Q6UXG8 5 181040225-181061521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 242.8;breast: 193.5" "Cell type enriched" "Detected in many" 6 "Adipocytes: 794.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 9.6" "Adipose visceral - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA043429 Approved "Nuclear membrane,Vesicles" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Nuclear membrane" Vesicles "HPA043429: AB_10961264" "unprognostic (2.69e-1)" "unprognostic (1.44e-2)" "unprognostic (5.76e-2)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.07e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.55e-9)" "unprognostic (2.15e-2)" "unprognostic (8.51e-2)" "unprognostic (1.78e-1)" "unprognostic (1.93e-3)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (2.71e-2)" "unprognostic (3.43e-1)" "unprognostic (2.50e-1)" "unprognostic (4.56e-2)" C1QTNF12 "ADIPOLIN, C1QDC2, CTRP12, FAM132A, MGC105127" ENSG00000184163 "C1q and TNF related 12" Q5T7M4 1 1242446-1246722 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.6;skin 1: 6.4" "Group enriched" "Detected in many" 4 "Distal enterocytes: 146.5;Proximal enterocytes: 213.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.5" "Adipose visceral - Endothelial cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024107 Uncertain Approved Vesicles "Secreted to blood" "Complement pathway" NA NA 38200000 "Cluster 45: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA024107: AB_2101207" "unprognostic (1.10e-2)" "unprognostic (5.68e-3)" "unprognostic (3.45e-1)" "unprognostic (1.24e-2)" "unprognostic (6.60e-3)" "unprognostic (2.43e-1)" "unprognostic (2.67e-3)" "unprognostic (1.01e-2)" "unprognostic (2.58e-1)" "unprognostic (1.05e-2)" "unprognostic (8.02e-3)" "unprognostic (1.10e-2)" "unprognostic (9.68e-3)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" CA4 "CAIV, Car4, RP17" ENSG00000167434 "Carbonic anhydrase 4" P22748 17 60149942-60170899 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 254.9" "Cell type enriched" "Detected in many" 5 "Paneth cells: 4309.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.3" "Region enriched" "Detected in all" 5 "cerebellum: 173.8" "Immune cell enriched" "Detected in some" 7 "neutrophil: 100.0" "Lineage enriched" "Detected in single" 1000 "granulocytes: 100.0" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3;liver cancer: 7.8;prostate cancer: 7.4" "Adipose visceral - Endothelial cells, Colon - Colon enterocytes" "Region enriched" "Detected in all" 5 "cerebellum: 300.3" "Low region specificity" "Detected in all" "HPA011089, HPA017258" Enhanced Uncertain Vesicles,Cytosol NA NA 190000 "Cluster 21: Neutrophils - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 5: Enterocytes - Absorption" 1 Cytosol Vesicles "HPA011089: AB_1845996, HPA017258: AB_1845997" "unprognostic (2.07e-2)" "unprognostic (7.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.78e-3)" "unprognostic (8.42e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (5.84e-2)" "unprognostic (7.76e-2)" "unprognostic (9.74e-2)" "unprognostic (1.54e-1)" "unprognostic (1.71e-2)" "unprognostic (2.68e-3)" "unprognostic (8.59e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-2)" CA8 "CALS, CARP" ENSG00000178538 "Carbonic anhydrase 8" P35219 8 60185412-60281400 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.2;parathyroid gland: 38.9" "Cell type enhanced" "Detected in many" "Astrocytes: 87.9;Oligodendrocyte precursor cells: 121.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Region enhanced" "Detected in all" "cerebellum: 36.0" "Immune cell enriched" "Detected in some" 24 "basophil: 76.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 76.2" "Cancer enhanced" "Detected in many" "skin cancer: 9.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Region enriched" "Detected in all" 38 "cerebellum: 1260.6" "Region enriched" "Detected in all" 9 "cerebellum: 115.2" "HPA024748, CAB025545, CAB047309" Enhanced NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 61: Brain - Neuronal signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 11 "CAB025545: , CAB047309: , HPA024748: AB_1846003" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "unprognostic (4.43e-2)" "unprognostic (3.46e-3)" "unprognostic (6.67e-2)" "unprognostic (3.19e-1)" "unprognostic (3.85e-2)" "unprognostic (3.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.79e-5)" "unprognostic (3.23e-2)" "unprognostic (1.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.71e-2)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" CALM1 "CALML2, CAMI, DD132, PHKD, PHKD1" ENSG00000198668 "Calmodulin 1" P0DP23 14 90396502-90408268 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "CAB018558, HPA044999" Supported Supported Cytosol NA NA 75000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 Cytosol "CAB018558: AB_2069454, HPA044999: AB_2679177" "unprognostic (5.35e-3)" "unprognostic (3.96e-1)" "unprognostic (4.99e-3)" "unprognostic (2.91e-2)" "unprognostic (1.07e-1)" "unprognostic (2.87e-2)" "unprognostic (1.99e-3)" "unprognostic (1.52e-1)" "unprognostic (6.44e-2)" "unprognostic (1.16e-3)" "prognostic favorable (5.62e-4)" "unprognostic (2.77e-1)" "prognostic favorable (6.49e-4)" "unprognostic (2.66e-1)" "unprognostic (2.68e-1)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.38e-5)" CAPN11 ENSG00000137225 "Calpain 11" Q9UMQ6 6 44158811-44184401 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 29.5" "Group enriched" "Detected in some" 7 "Adipocytes: 13.0;Breast myoepithelial cells: 11.6;Early spermatids: 25.6;Late spermatids: 10.6;Spermatocytes: 38.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Leukemia: 1.0;Rhabdoid: 4.0" "Adipose visceral - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB018070, HPA030955" Enhanced NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "CAB018070: AB_2069481, HPA030955: AB_2673672" "unprognostic (2.20e-2)" "unprognostic (1.87e-1)" "unprognostic (1.64e-2)" "unprognostic (2.75e-1)" "unprognostic (6.22e-2)" "unprognostic (3.34e-2)" "unprognostic (3.99e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (8.96e-2)" "unprognostic (1.01e-1)" "unprognostic (2.13e-1)" "unprognostic (3.62e-6)" "unprognostic (2.38e-2)" "unprognostic (3.51e-1)" "unprognostic (2.27e-2)" "unprognostic (8.89e-2)" CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.9" "Cell type enhanced" "Detected in many" "Adipocytes: 23.2;Ductal cells: 25.3;Endothelial cells: 28.4;Intestinal goblet cells: 26.1;Lymphatic endothelial cells: 29.0;Proximal enterocytes: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Prostate - Endothelial cells, Testis - Sertoli cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 83 "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" CBFA2T3 "ETO2, MTG16, MTGR2, RUNX1T3, ZMYND4" ENSG00000129993 "CBFA2/RUNX1 partner transcriptional co-repressor 3" O75081 16 88874858-88977207 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Repressor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.7;lymphoid tissue: 28.7" "Cell type enhanced" "Detected in many" "B-cells: 31.4;dendritic cells: 60.5;granulocytes: 23.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leukemia: 54.3;lymphoma: 29.3;Myeloma: 21.4" "Adipose visceral - Endothelial cells, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059931, HPA062423, HPA065890" Approved Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 28: Dendritic cells - Antigen presentation" 2 Nucleoplasm "HPA059931: AB_2684168, HPA062423: AB_2684758, HPA065890: AB_2685575" "unprognostic (2.47e-1)" "unprognostic (2.03e-2)" "unprognostic (9.24e-3)" "unprognostic (2.62e-1)" "unprognostic (1.98e-1)" "prognostic favorable (3.95e-4)" "unprognostic (1.13e-3)" "unprognostic (1.69e-2)" "unprognostic (1.25e-1)" "unprognostic (2.10e-1)" "unprognostic (7.30e-3)" "unprognostic (2.38e-1)" "unprognostic (7.04e-5)" "unprognostic (2.18e-1)" "unprognostic (4.08e-2)" "unprognostic (4.62e-2)" "unprognostic (9.35e-3)" CCDC178 "C18orf34, FLJ44050" ENSG00000166960 "Coiled-coil domain containing 178" Q5BJE1 18 32937402-33441101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.6;ovary: 9.6;testis: 15.0" "Group enriched" "Detected in some" 4 "Adipocytes: 31.3;Early spermatids: 104.5;Late spermatids: 75.4;Spermatocytes: 46.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 2.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 18: Early spermatids - Unknown function" "unprognostic (1.15e-2)" "unprognostic (2.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (9.88e-2)" "unprognostic (2.58e-1)" "unprognostic (2.75e-1)" "unprognostic (2.58e-3)" "unprognostic (2.92e-1)" "unprognostic (5.95e-4)" "unprognostic (4.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.94e-4)" "unprognostic (2.86e-1)" "unprognostic (1.42e-3)" "unprognostic (9.03e-3)" CCDC85A KIAA1912 ENSG00000055813 "Coiled-coil domain containing 85A" Q96PX6 2 56183990-56386172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.1;brain: 12.4" "Group enriched" "Detected in some" 4 "Excitatory neurons: 221.4;Inhibitory neurons: 153.4;Microglial cells: 57.3" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043106, HPA057020" Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 65: Neurons - Synaptic function" "HPA043106: AB_10794770, HPA057020: AB_2683311" "unprognostic (2.29e-1)" "unprognostic (1.28e-1)" "unprognostic (6.87e-2)" "unprognostic (3.66e-2)" "unprognostic (7.87e-2)" "unprognostic (7.62e-2)" "unprognostic (3.07e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-1)" "unprognostic (6.55e-5)" "unprognostic (3.28e-2)" "unprognostic (1.00e-1)" "unprognostic (2.88e-2)" "unprognostic (1.83e-2)" CCM2L "C20orf160, dJ310O13.5" ENSG00000101331 "CCM2 like scaffold protein" Q9NUG4 20 32010438-32032180 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 138.2" "Group enriched" "Detected in some" 8 "Adipocytes: 41.4;Endothelial cells: 29.1;Lymphatic endothelial cells: 21.8;Microglial cells: 12.5;Oocytes: 18.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008434, HPA071063" Uncertain Approved Nucleoplasm NA NA "Cluster 47: Spleen - Immune response" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 Nucleoplasm "HPA008434: AB_1845671, HPA071063: AB_2686339" "unprognostic (1.71e-1)" "unprognostic (4.64e-2)" "unprognostic (2.43e-3)" "unprognostic (5.84e-3)" "unprognostic (1.91e-1)" "unprognostic (3.09e-3)" "unprognostic (1.27e-3)" "unprognostic (2.37e-1)" "unprognostic (2.04e-1)" "unprognostic (4.34e-2)" "unprognostic (1.00e-3)" "unprognostic (7.84e-2)" "unprognostic (4.66e-3)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Lipid transport, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1480.0" "Group enriched" "Detected in many" 4 "Adipocytes: 2837.3;Cardiomyocytes: 872.7;Hofbauer cells: 1253.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 965.2;intermediate monocyte: 271.3;myeloid DC: 507.9" "Group enriched" "Detected in all" 46 "dendritic cells: 507.9;monocytes: 965.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 57.4" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Liver - Sinusoid Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 13.2" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 5300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Golgi apparatus" "CAB025866: , HPA002018: AB_1078464, HPA071026: AB_2732170" "unprognostic (7.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.06e-3)" "unprognostic (6.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (9.35e-2)" "unprognostic (2.64e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.84e-3)" "prognostic unfavorable (4.47e-4)" "unprognostic (7.05e-3)" "unprognostic (4.87e-2)" "unprognostic (2.73e-3)" CDC37 P50CDC37 ENSG00000105401 "Cell division cycle 37, HSP90 cochaperone" Q16543 19 10391133-10420121 "Cancer-related genes, Predicted intracellular proteins, Transporters" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003928, CAB004214" Supported Supported Cytosol NA NA 610000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 79: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 124 Cytosol "CAB004214: AB_627232, HPA003928: AB_1846373" "unprognostic (2.40e-1)" "unprognostic (1.06e-1)" "unprognostic (1.27e-1)" "unprognostic (2.33e-2)" "unprognostic (2.46e-3)" "unprognostic (6.21e-2)" "unprognostic (1.37e-1)" "unprognostic (7.90e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-3)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.84e-2)" "prognostic favorable (2.33e-4)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (3.02e-2)" CDC42BPA "FLJ23347, KIAA0451, MRCK, MRCKA, PK428" ENSG00000143776 "CDC42 binding protein kinase alpha" Q5VT25 1 226989865-227318492 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 303.8;Excitatory neurons: 432.5;Inhibitory neurons: 458.5;Oligodendrocyte precursor cells: 416.9;Oligodendrocytes: 625.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB070414, HPA071252" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 65: Neurons - Synaptic function" 1 "Plasma membrane, Cytosol" "CAB070414: AB_11156796, HPA071252: AB_2686374" "unprognostic (3.67e-3)" "unprognostic (1.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.78e-2)" "unprognostic (3.04e-1)" "unprognostic (5.90e-2)" "unprognostic (7.89e-2)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.93e-1)" "unprognostic (4.88e-2)" "unprognostic (2.87e-2)" "unprognostic (7.73e-3)" "unprognostic (1.35e-1)" "unprognostic (1.70e-1)" "unprognostic (9.79e-2)" "unprognostic (1.21e-2)" CDH13 CDHH ENSG00000140945 "Cadherin 13" P55290 16 82626965-83800640 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 55.1;skeletal muscle: 66.1;tongue: 55.5" "Group enriched" "Detected in many" 4 "Excitatory neurons: 316.9;Inhibitory neurons: 827.4;Oligodendrocyte precursor cells: 315.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.3" "Group enriched" "Detected in many" 5 "granulocytes: 1.4;monocytes: 4.3" "Cancer enhanced" "Detected in many" "Brain cancer: 66.5;testis cancer: 95.3" "Adipose visceral - Endothelial cells, Lung - Fibroblast_1, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001380, CAB025863" Enhanced Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 240000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Neurons - Synaptic function" 2 "Plasma membrane" "CAB025863: , HPA001380: AB_1078371" "unprognostic (2.50e-2)" "unprognostic (2.75e-2)" "unprognostic (5.61e-2)" "unprognostic (4.06e-1)" "unprognostic (4.88e-2)" "unprognostic (3.30e-3)" "unprognostic (3.01e-1)" "unprognostic (5.76e-2)" "unprognostic (3.49e-2)" "unprognostic (3.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.73e-6)" "unprognostic (5.16e-3)" "unprognostic (2.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 228.1" "Cell type enhanced" "Detected in many" "Adipocytes: 292.8;Endothelial cells: 190.1;Late spermatids: 84.9;Lymphatic endothelial cells: 152.3;Syncytiotrophoblasts: 119.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.0;pancreatic cancer: 9.6;Rhabdoid: 12.8" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 6 "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" CEACAM1 "BGP, BGP1, CD66a" ENSG00000079385 "CEA cell adhesion molecule 1" P13688 19 42507304-42561234 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 238.1" "Group enriched" "Detected in many" 5 "Distal enterocytes: 797.7;Paneth cells: 241.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 43.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "eosinophil: 44.1;neutrophil: 26.9" "Lineage enriched" "Detected in many" 13 "granulocytes: 44.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Colon - Colon enterocytes, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skin - Eccrine sweat gland cells" "CAB002146, HPA011041" Enhanced "Intracellular and membrane" "No annotated function" NA NA 130000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 5: Enterocytes - Absorption" 2 "CAB002146: AB_563614, HPA011041: AB_1078481" "unprognostic (7.13e-3)" "unprognostic (2.15e-1)" "unprognostic (2.67e-2)" "prognostic favorable (6.32e-7)" "unprognostic (3.04e-1)" "unprognostic (1.80e-3)" "unprognostic (1.21e-1)" "unprognostic (4.45e-2)" "unprognostic (4.43e-1)" "unprognostic (5.46e-3)" "unprognostic (4.87e-2)" "unprognostic (4.03e-1)" "unprognostic (1.92e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (7.55e-2)" "unprognostic (5.52e-3)" CHN1 "ARHGAP2, CHN, DURS2, n-chimerin, RhoGAP2" ENSG00000128656 "Chimerin 1" P15882 2 174798809-175005381 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "brain: 860.2" "Cell type enhanced" "Detected in many" "Astrocytes: 185.2;Excitatory neurons: 576.4;Horizontal cells: 95.0;Inhibitory neurons: 107.0;Microglial cells: 93.0;Oligodendrocyte precursor cells: 140.6" "Cancer enhanced" "Detected in all" "glioma: 18.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 6.8;memory CD8 T-cell: 2.2;T-reg: 8.5" "Lineage enriched" "Detected in single" 19 "T-cells: 8.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036111 Approved Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" 4 Cytosol "HPA036111: AB_10671241" "unprognostic (3.18e-3)" "unprognostic (4.19e-2)" "unprognostic (9.69e-2)" "unprognostic (3.42e-3)" "unprognostic (1.92e-1)" "unprognostic (2.65e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "unprognostic (3.71e-2)" "unprognostic (1.34e-2)" "unprognostic (5.29e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (7.31e-3)" "unprognostic (4.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.46e-2)" CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 425.6;breast: 407.2;choroid plexus: 418.8;lung: 386.5" "Group enriched" "Detected in many" 12 "Adipocytes: 2773.0;Endothelial cells: 835.9;Lymphatic endothelial cells: 1261.5" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 19.0;naive CD4 T-cell: 4.8;neutrophil: 5.9" "Group enriched" "Detected in many" 29 "granulocytes: 19.0;T-cells: 4.8" "Cancer enhanced" "Detected in some" "Bone cancer: 6.4;cervical cancer: 13.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 34: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 33 "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 379.0;Endothelial cells: 326.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "Leukemia: 8.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 12 "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" CMTM8 CKLFSF8 ENSG00000170293 "CKLF like MARVEL transmembrane domain containing 8" Q8IZV2 3 32238679-32370321 "Predicted membrane proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 46.2" "Cell type enhanced" "Detected in many" "Adipocytes: 90.2;Cytotrophoblasts: 107.8;Syncytiotrophoblasts: 118.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055077, HPA073258" Approved Approved Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 47: Endothelial cells - Vasculature" "Cluster 6: Leukemia - Signal transduction" "Cluster 17: Breast glandular cells - Lactation" 3 Nucleoplasm "HPA055077: AB_2682691, HPA073258: AB_2686591" "unprognostic (9.88e-3)" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "unprognostic (3.83e-1)" "unprognostic (1.14e-1)" "unprognostic (3.33e-2)" "unprognostic (9.46e-2)" "unprognostic (5.67e-2)" "unprognostic (8.85e-2)" "unprognostic (1.29e-1)" "unprognostic (7.59e-2)" "unprognostic (2.56e-1)" "prognostic favorable (2.80e-4)" "unprognostic (1.78e-2)" "unprognostic (2.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" COL15A1 ENSG00000204291 "Collagen type XV alpha 1 chain" P39059 9 98943179-99070792 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 221.6" "Cell type enhanced" "Detected in many" "Adipocytes: 292.9;Endometrial stromal cells: 98.0;Endothelial cells: 147.7;Fibroblasts: 163.4;Leydig cells: 324.7;Peritubular cells: 458.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 13.8;skin cancer: 14.8" "Adipose visceral - Endothelial cells, Colon - Smooth muscle cells, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Skin - Fibroblast_1, Testis - Peritubular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "spinal cord: 56.0" "HPA017913, HPA017915" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "Developmental protein" NA NA 28000000 "Cluster 58: Placenta - Pregnancy" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Endoplasmic reticulum" "HPA017913: AB_1847099, HPA017915: AB_1847100" "unprognostic (4.30e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-2)" "unprognostic (2.09e-1)" "unprognostic (1.09e-2)" "prognostic favorable (5.47e-4)" "unprognostic (3.08e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-3)" "unprognostic (3.66e-3)" "unprognostic (8.98e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (3.08e-4)" CPD GP180 ENSG00000108582 "Carboxypeptidase D" O75976 17 30378927-30469989 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ionocytes: 181.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 25.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052796 Approved Approved Cytosol NA NA 1700000 "Cluster 35: Neutrophils - Protein binding" "Cluster 78: Testis - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Neutrophils - Degranulation" Cytosol "HPA052796: AB_2681953" "unprognostic (1.05e-1)" "unprognostic (1.31e-1)" "unprognostic (3.05e-2)" "unprognostic (3.62e-2)" "unprognostic (6.13e-2)" "unprognostic (1.65e-1)" "unprognostic (7.97e-3)" "unprognostic (4.45e-2)" "unprognostic (2.07e-2)" "unprognostic (2.96e-1)" "unprognostic (1.62e-1)" "unprognostic (3.16e-1)" "unprognostic (1.58e-1)" "unprognostic (3.74e-2)" "unprognostic (7.25e-2)" "unprognostic (3.36e-1)" "unprognostic (1.08e-1)" CPNE8 ENSG00000139117 "Copine 8" Q86YQ8 12 38646822-38907430 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 80.1;Excitatory neurons: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038600 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Liver - Plasma proteins" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 2 "HPA038600: AB_10674690" "unprognostic (1.57e-1)" "unprognostic (3.07e-1)" "unprognostic (3.38e-1)" "unprognostic (3.78e-3)" "unprognostic (8.93e-3)" "unprognostic (6.28e-3)" "unprognostic (6.74e-2)" "unprognostic (8.44e-2)" "unprognostic (5.40e-3)" "unprognostic (4.29e-1)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (3.21e-1)" "unprognostic (5.13e-2)" "unprognostic (8.73e-3)" CRIP2 "CRP2, ESP1" ENSG00000182809 "Cysteine rich protein 2" P52943 14 105472962-105480162 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 1078.5" "Cell type enhanced" "Detected in many" "Adipocytes: 475.2;Cardiomyocytes: 785.0;Endothelial cells: 467.9;Lymphatic endothelial cells: 504.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 52.3;memory CD4 T-cell: 80.5;naive B-cell: 111.0;T-reg: 116.0" "Group enriched" "Detected in all" 30 "B-cells: 111.0;T-cells: 116.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Prostate - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042664 Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA 160000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 30: Heart muscle - Heart development" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" Nucleoli "Nucleoplasm, Plasma membrane" "HPA042664: AB_10797017" "unprognostic (2.68e-1)" "unprognostic (6.53e-3)" "unprognostic (2.11e-3)" "unprognostic (2.19e-1)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.63e-2)" "unprognostic (2.56e-1)" "unprognostic (3.20e-3)" "unprognostic (9.68e-2)" "unprognostic (6.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (6.25e-2)" "unprognostic (2.35e-2)" "unprognostic (2.39e-2)" "unprognostic (8.26e-3)" CTBP2 ribeye ENSG00000175029 "C-terminal binding protein 2" P56545 10 124984317-125161170 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023559, HPA023564, CAB031916, HPA044971, CAB079018" Approved Approved Approved Nucleoplasm NA NA 10000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Retina & Testis - Cilium" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 37: Glandular & Luminal cells - Unknown function" 21 Nucleoplasm "CAB031916: AB_2086774, CAB079018: , HPA023559: AB_1847309, HPA023564: AB_1847310, HPA044971: AB_2679161" "unprognostic (8.69e-2)" "unprognostic (1.27e-2)" "unprognostic (4.14e-2)" "unprognostic (1.41e-2)" "unprognostic (6.84e-3)" "unprognostic (4.05e-3)" "unprognostic (3.63e-2)" "unprognostic (5.60e-3)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (3.24e-2)" "unprognostic (3.99e-3)" "prognostic favorable (1.70e-4)" "unprognostic (4.34e-2)" "unprognostic (1.48e-1)" "unprognostic (2.19e-2)" "unprognostic (1.62e-1)" CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 172.7;skin 1: 421.1" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 541.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 45: Eosinophils - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 14 "Nucleoplasm, Cytosol" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 188.3;Endothelial cells: 164.8;Microglial cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.5" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.5" "Cancer enhanced" "Detected in some" "Bone cancer: 14.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" DACH1 DACH ENSG00000276644 "Dachshund family transcription factor 1" Q9UI36 13 71437966-71867204 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 20.2" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Excitatory neurons: 74.1;Late spermatids: 99.2;Microglial cells: 136.9;Muller glia cells: 122.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 6.0;eosinophil: 11.3;NK-cell: 5.7;plasmacytoid DC: 9.3" "Group enriched" "Detected in many" 29 "dendritic cells: 9.3;granulocytes: 11.3;NK-cells: 5.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Region enriched" "Detected in all" 5 "basal ganglia: 38.8" "Region enriched" "Detected in all" 6 "basal ganglia: 45.2" "HPA012672, HPA012938, HPA073222" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 39: Retina & Testis - Cilium" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 2 "Nucleoplasm, Nuclear speckles" "HPA012672: AB_1847466, HPA012938: , HPA073222: " "unprognostic (3.16e-1)" "unprognostic (5.26e-2)" "unprognostic (1.41e-2)" "unprognostic (2.36e-1)" "unprognostic (4.21e-2)" "unprognostic (5.63e-2)" "unprognostic (2.22e-2)" "unprognostic (8.08e-3)" "unprognostic (2.12e-2)" "unprognostic (2.50e-1)" "unprognostic (3.04e-3)" "unprognostic (4.37e-1)" "unprognostic (2.18e-2)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (5.17e-2)" DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 171.1;Endothelial cells: 140.5;Lymphatic endothelial cells: 151.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" "No annotated function" NA NA 940000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" DOCK6 "KIAA1395, ZIR1" ENSG00000130158 "Dedicator of cytokinesis 6" Q96HP0 19 11199295-11262524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 63.3;Endothelial cells: 40.9;Gastric mucus-secreting cells: 32.4;Lymphatic endothelial cells: 36.9;Microglial cells: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049423, HPA049424" Approved Supported Cytosol NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Cytosol "HPA049423: AB_2680760, HPA049424: AB_2680761" "unprognostic (2.69e-2)" "unprognostic (2.27e-1)" "unprognostic (9.51e-2)" "unprognostic (3.35e-2)" "unprognostic (4.72e-3)" "prognostic favorable (9.09e-4)" "unprognostic (2.54e-2)" "unprognostic (4.91e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (2.57e-1)" "unprognostic (7.89e-2)" "unprognostic (1.25e-3)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (5.41e-2)" "unprognostic (2.95e-1)" DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453561-71686763 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 51.6;skeletal muscle: 122.5" "Cell type enhanced" "Detected in many" "Endothelial cells: 37.3;Excitatory neurons: 33.6;Lymphatic endothelial cells: 85.1;Oligodendrocytes: 58.4;Oocytes: 35.3;Skeletal myocytes: 38.1;Syncytiotrophoblasts: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 51.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 51.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophil_2, Thyroid - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Neutrophils - Degranulation" 16 "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 17 "Adipocytes: 239.5;Endothelial cells: 292.0;Lymphatic endothelial cells: 562.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 15.8;pancreatic cancer: 11.4" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 1 "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" EFNB2 "EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228" ENSG00000125266 "Ephrin B2" P52799 13 106489745-106535662 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 218.0;Endothelial cells: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008999, CAB009368" Supported Supported Nucleoplasm,Cytosol NA NA 940000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 Nucleoplasm Cytosol "CAB009368: AB_2095700, HPA008999: AB_1078721" "unprognostic (1.70e-1)" "unprognostic (1.95e-3)" "unprognostic (1.72e-1)" "unprognostic (5.22e-3)" "unprognostic (4.52e-3)" "prognostic unfavorable (3.11e-6)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (2.09e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.70e-5)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-1)" "unprognostic (4.62e-2)" "unprognostic (2.27e-3)" EFR3B "FLJ37871, KIAA0953" ENSG00000084710 "EFR3 homolog B" Q9Y2G0 2 25042076-25159135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.0;skeletal muscle: 19.1" "Cell type enhanced" "Detected in many" "Astrocytes: 120.4;Excitatory neurons: 56.6;Horizontal cells: 32.1;Inhibitory neurons: 106.3;Late spermatids: 45.6;Microglial cells: 51.9;Oligodendrocytes: 47.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Colon - Enteric glia cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038089, HPA071831" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Cerebellum - Nervous system development" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 8: Neurons - Neuronal signaling" "Plasma membrane" "Actin filaments, Cytosol" "HPA038089: AB_10672618, HPA071831: " "unprognostic (9.31e-2)" "unprognostic (3.92e-1)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.24e-3)" "unprognostic (3.82e-1)" "unprognostic (3.42e-1)" "unprognostic (1.32e-2)" "unprognostic (4.49e-6)" "unprognostic (4.83e-2)" "unprognostic (4.43e-2)" "unprognostic (1.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 783.1;Endothelial cells: 505.6;Hofbauer cells: 261.1;Lymphatic endothelial cells: 322.0;Spermatogonia: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.6;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" "Developmental protein" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" ELK3 "ERP, NET, SAP2" ENSG00000111145 "ETS transcription factor ELK3" P41970 12 96194375-96269824 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 169.0;Endothelial cells: 165.8;Lymphatic endothelial cells: 384.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001600 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 9 Nucleoplasm Mitochondria "HPA001600: AB_1078752" "unprognostic (3.11e-1)" "unprognostic (8.81e-3)" "unprognostic (6.38e-2)" "unprognostic (5.77e-2)" "unprognostic (7.18e-3)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (5.10e-3)" "unprognostic (7.39e-2)" "prognostic unfavorable (4.93e-4)" "unprognostic (2.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.20e-3)" "unprognostic (2.90e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (2.05e-2)" ELMO1 "CED-12, CED12, ELMO-1, KIAA0281" ENSG00000155849 "Engulfment and cell motility 1" Q92556 7 36852906-37449223 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 113.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 229.0;Microglial cells: 495.6;Oligodendrocyte precursor cells: 266.5;Oligodendrocytes: 1314.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 70.9;lymphoma: 106.2;Myeloma: 81.9" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Hepatocytes, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 51: Oligodendrocytes - Unknown function" 7 "unprognostic (1.77e-2)" "unprognostic (8.29e-3)" "unprognostic (1.55e-1)" "unprognostic (1.19e-2)" "unprognostic (3.69e-1)" "unprognostic (4.09e-2)" "unprognostic (3.01e-2)" "unprognostic (3.53e-3)" "unprognostic (1.34e-1)" "unprognostic (1.71e-1)" "prognostic favorable (4.62e-4)" "unprognostic (3.59e-1)" "prognostic unfavorable (3.27e-5)" "unprognostic (1.65e-2)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (3.16e-3)" EMCN MUC14 ENSG00000164035 Endomucin Q9ULC0 4 100395341-100880126 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 394.2;Endothelial cells: 263.1;Lymphatic endothelial cells: 174.4;Microglial cells: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005928 Approved "Intracellular and membrane" "No annotated function" NA NA 470000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA005928: AB_1078735" "unprognostic (8.01e-2)" "unprognostic (2.13e-4)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (2.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (1.03e-4)" "unprognostic (3.65e-1)" "unprognostic (5.94e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-2)" "unprognostic (3.10e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.75e-3)" "unprognostic (2.36e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 223.6" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 1: 3419.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (other), Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 27: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Alveolar cells - Lung function" Nucleoplasm Cytosol "HPA014711: AB_1848147, HPA070816: " "unprognostic (1.75e-1)" "unprognostic (4.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (9.27e-2)" "unprognostic (8.90e-2)" "unprognostic (2.41e-2)" "unprognostic (4.40e-1)" "unprognostic (1.86e-1)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (2.85e-8)" "unprognostic (9.54e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (9.52e-2)" ENG "CD105, END, HHT1, ORW, ORW1" ENSG00000106991 Endoglin P17813 9 127815013-127854658 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 511.3" "Group enriched" "Detected in many" 4 "Adipocytes: 404.5;Endothelial cells: 476.2;Extravillous trophoblasts: 342.8;Leydig cells: 473.5;Peritubular cells: 1364.0;Syncytiotrophoblasts: 471.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 19.9;intermediate monocyte: 28.2;myeloid DC: 10.3;NK-cell: 7.6;non-classical monocyte: 22.2" "Group enriched" "Detected in many" 4 "dendritic cells: 10.3;monocytes: 28.2;NK-cells: 7.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000096, HPA011862, HPA067440, CAB072873" Enhanced Supported "Nuclear bodies,Plasma membrane" NA NA 280000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "Plasma membrane" "Nuclear bodies" "CAB000096: AB_563482, CAB072873: AB_2665725, HPA011862: AB_1846217, HPA067440: AB_2685840" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "prognostic favorable (6.61e-4)" "prognostic favorable (5.62e-6)" "unprognostic (2.15e-1)" "unprognostic (4.06e-1)" "unprognostic (3.87e-2)" "unprognostic (2.20e-2)" "unprognostic (8.98e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (3.33e-3)" "unprognostic (7.35e-2)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 399.3;placenta: 430.9" "Cell type enhanced" "Detected in all" "Adipocytes: 795.3;Endothelial cells: 626.4;Extravillous trophoblasts: 336.1;Syncytiotrophoblasts: 365.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.7;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported "Nucleoplasm,Actin filaments,Cytokinetic bridge,Cytosol" Yes NA "Cluster 46: Basophils - Proteolysis" "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 9 Nucleoplasm "Actin filaments, Cytokinetic bridge, Cytosol" "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" EPB41L4A NBL4 ENSG00000129595 "Erythrocyte membrane protein band 4.1 like 4A" Q9HCS5 5 112142441-112419313 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 154.2;Oligodendrocytes: 60.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036580 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Plasma membrane" Nucleoplasm "HPA036580: AB_10669908" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (1.92e-3)" "unprognostic (3.64e-2)" "unprognostic (4.73e-2)" "unprognostic (5.59e-3)" "unprognostic (4.40e-2)" "unprognostic (8.38e-2)" "unprognostic (1.90e-1)" "unprognostic (3.97e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.65e-5)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (2.73e-1)" "unprognostic (1.92e-1)" EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 30.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 68.2;Inhibitory neurons: 101.4;Microglial cells: 98.4;Oligodendrocytes: 44.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Peritubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" Receptor NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" 2 "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 85.9;Endothelial cells: 104.8;Lymphatic endothelial cells: 114.2;Microglial cells: 84.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Leukemia: 24.0;prostate cancer: 21.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 6: Leukemia - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 7 Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 380.0;Endothelial cells: 268.6;Smooth muscle cells: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Cancer enhanced" "Detected in many" "Leukemia: 19.0;pancreatic cancer: 16.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 264.5" "Cell type enhanced" "Detected in many" "Adipocytes: 240.7;Endothelial cells: 172.4;NK-cells: 639.3;T-cells: 395.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 12 Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" EXOC3L1 "EXOC3L, FLJ35539, FLJ35587" ENSG00000179044 "Exocyst complex component 3 like 1" Q86VI1 16 67184379-67190185 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 43.6" "Cell type enhanced" "Detected in many" "Adipocytes: 22.9;Endothelial cells: 15.7;Granulosa cells: 14.1;Leydig cells: 15.9;Lymphatic endothelial cells: 25.6;Ovarian stromal cells: 20.8;Peritubular cells: 17.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA029574 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 47: Spleen - Immune response" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 6: Ovarian stromal cells - Transcription" 7 "Vesicles, Plasma membrane" "HPA029574: AB_10602495" "unprognostic (1.15e-2)" "unprognostic (4.91e-2)" "unprognostic (6.87e-3)" "unprognostic (2.09e-3)" "unprognostic (2.33e-1)" "unprognostic (2.46e-2)" "unprognostic (6.77e-2)" "unprognostic (3.98e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-2)" "unprognostic (6.48e-3)" "unprognostic (2.88e-1)" "unprognostic (6.64e-3)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.35e-1)" EXOC3L2 "FLJ36147, XTP7" ENSG00000283632 "Exocyst complex component 3 like 2" 19 45212370-45245407 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "kidney: 18.4;thyroid gland: 17.3" "Cell type enhanced" "Detected in some" "Adipocytes: 18.6;Endothelial cells: 26.9;Oocytes: 52.9;Spermatogonia: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 3.0" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041595, HPA061110" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Vesicles "Nucleoplasm, Golgi apparatus, Cytosol" "HPA041595: AB_10794521, HPA061110: AB_2684431" FAM167B "C1orf90, DIORA-2, MGC10820" ENSG00000183615 "Family with sequence similarity 167 member B" Q9BTA0 1 32247222-32248856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.8" "Cell type enhanced" "Detected in many" "Adipocytes: 62.7;Endothelial cells: 78.3;Fibroblasts: 24.9;Smooth muscle cells: 17.0" "Cancer enhanced" "Detected in all" "melanoma: 46.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Lineage enriched" "Detected in single" 5 "T-cells: 1.7" "Cancer enriched" "Detected in many" 6 "skin cancer: 47.4" "Adipose visceral - Endothelial cells, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebellum: 1.0" "HPA029398, HPA062074" Uncertain Approved "Actin filaments" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Actin filaments" "HPA029398: AB_10602807, HPA062074: AB_2684677" "unprognostic (2.16e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (6.03e-2)" "unprognostic (1.74e-2)" "unprognostic (3.36e-3)" "unprognostic (7.44e-3)" "unprognostic (3.64e-1)" "unprognostic (3.00e-3)" "unprognostic (1.02e-2)" "unprognostic (1.30e-2)" "unprognostic (8.89e-2)" "unprognostic (4.80e-2)" "unprognostic (2.69e-2)" "unprognostic (1.60e-1)" "unprognostic (8.04e-2)" "unprognostic (5.08e-2)" FAM241A "C4orf32, FLJ39370" ENSG00000174749 "Family with sequence similarity 241 member A" Q8N8J7 4 112145454-112195256 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 268.1;Endothelial cells: 98.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062443, HPA069294" Approved Enhanced "Golgi apparatus" No No "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Golgi apparatus" "HPA062443: AB_2684765, HPA069294: AB_2686111" "unprognostic (3.07e-1)" "unprognostic (1.11e-2)" "unprognostic (2.42e-2)" "unprognostic (5.58e-2)" "unprognostic (4.68e-2)" "unprognostic (1.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.16e-1)" "unprognostic (1.21e-1)" "unprognostic (5.05e-2)" "unprognostic (4.81e-2)" "unprognostic (5.25e-2)" "unprognostic (9.20e-3)" "prognostic unfavorable (8.87e-4)" "unprognostic (4.08e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-2)" FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 50.5;Endothelial cells: 48.2;Lymphatic endothelial cells: 34.5;Microglial cells: 24.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 6.2;testis cancer: 6.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Testis - Spermatogonia, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "Plasma membrane" "HPA014436: , HPA014536: AB_1848518, HPA019191: AB_1848519" "unprognostic (2.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.28e-2)" "unprognostic (2.02e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (6.34e-2)" "unprognostic (5.53e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-2)" "prognostic favorable (7.50e-4)" FLI1 "EWSR2, FLI-1, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 68.2" "Cell type enhanced" "Detected in many" "B-cells: 61.8;Endothelial cells: 79.8;Kupffer cells: 88.8;Microglial cells: 221.0;monocytes: 70.9;NK-cells: 74.1;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 39.0;Myeloma: 29.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008398-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 294.8;Extravillous trophoblasts: 244.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 8 "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "placenta: 405.3" "Cell type enhanced" "Detected in many" "Adipocytes: 383.1;Endothelial cells: 364.4;Extravillous trophoblasts: 980.8;Microglial cells: 414.2;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 15.1;testis cancer: 39.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" Receptor NA NA 876000 87000 "Cluster 58: Placenta - Pregnancy" "Cluster 47: Endothelial cells - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" 6 "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" FMNL3 "DKFZp762B245, MGC45819, WBP3" ENSG00000161791 "Formin like 3" Q8IVF7 12 49636499-49708165 "Predicted intracellular proteins" Angiogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 72.6;granulocytes: 44.8;Microglial cells: 113.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 5.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Enteric glia cells, Liver - Vascular Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002552, HPA023201" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus, Vesicles, Plasma membrane" Cytosol "HPA002552: AB_1078862, HPA023201: AB_1848575" "unprognostic (2.97e-1)" "unprognostic (2.77e-3)" "unprognostic (4.97e-3)" "unprognostic (7.19e-2)" "unprognostic (5.42e-2)" "unprognostic (2.33e-3)" "unprognostic (5.37e-3)" "unprognostic (1.52e-2)" "unprognostic (2.83e-1)" "unprognostic (1.54e-1)" "unprognostic (6.67e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (1.04e-1)" "unprognostic (2.31e-1)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" FNBP1L "C1orf39, FLJ20275, TOCA1" ENSG00000137942 "Formin binding protein 1 like" Q5T0N5 1 93448118-93554661 "Predicted intracellular proteins" "Autophagy, Endocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 7.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.3" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065273 Approved Supported Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 54: Immune cells - T cell receptor" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 75: Serous glandular cells - Salivary secretion" 2 Cytosol "HPA065273: AB_2685452" "unprognostic (1.83e-1)" "unprognostic (4.28e-2)" "unprognostic (2.57e-3)" "unprognostic (8.46e-2)" "unprognostic (7.68e-2)" "unprognostic (8.65e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (5.89e-2)" "unprognostic (1.74e-1)" "unprognostic (6.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.37e-1)" "prognostic favorable (4.72e-7)" "unprognostic (3.59e-2)" "unprognostic (5.64e-2)" "unprognostic (2.74e-2)" "unprognostic (1.78e-1)" FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 82.1;skeletal muscle: 78.4;tongue: 71.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 93.1;Cardiomyocytes: 79.5;Cone photoreceptor cells: 107.0;Early spermatids: 107.6;Inhibitory neurons: 66.8;Late spermatids: 140.5;Oocytes: 105.9" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Enteric glia cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 57: Platelets - Hemostasis" 11 "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" GARRE1 KIAA0355 ENSG00000166398 "Granule associated Rac and RHOG effector 1" O15063 19 34254552-34355566 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 176.2;Lymphatic endothelial cells: 123.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014570 Uncertain Approved Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoplasm "HPA014570: AB_1852307" "unprognostic (1.88e-2)" "unprognostic (8.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.75e-2)" "unprognostic (2.17e-2)" "unprognostic (1.48e-3)" "unprognostic (9.05e-2)" "unprognostic (8.27e-2)" "prognostic unfavorable (2.82e-4)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.34e-1)" "unprognostic (7.73e-3)" "unprognostic (2.96e-2)" "unprognostic (1.86e-1)" "unprognostic (1.16e-1)" "unprognostic (1.67e-1)" GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 124.7" "Group enriched" "Detected in many" 4 "Adipocytes: 182.7;Endothelial cells: 224.2;Hofbauer cells: 118.3;Kupffer cells: 148.5;Lymphatic endothelial cells: 186.5;Macrophages: 108.2;NK-cells: 203.2;T-cells: 184.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 4.3;pancreatic cancer: 9.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 19: NK-cells - Adaptive immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" GIPC2 "FLJ20075, SEMCAP-2" ENSG00000137960 "GIPC PDZ domain containing family member 2" Q8TF65 1 77979542-78138444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.9;kidney: 39.9;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 117.4;Proximal tubular cells: 273.5;Undifferentiated cells: 58.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 6.6;colorectal cancer: 8.4;Gastric cancer: 6.4;liver cancer: 4.0;pancreatic cancer: 2.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051212, HPA062684" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 6 Nucleoplasm Cytosol "HPA051212: , HPA062684: AB_2684833" "unprognostic (1.72e-2)" "unprognostic (9.37e-2)" "prognostic favorable (5.49e-4)" "unprognostic (1.09e-2)" "unprognostic (1.43e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.35e-1)" "unprognostic (7.63e-2)" "unprognostic (2.22e-1)" "unprognostic (5.91e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.11e-6)" "unprognostic (6.55e-2)" "unprognostic (1.78e-1)" "unprognostic (4.18e-2)" "unprognostic (1.29e-1)" GIPC3 "C19orf64, DFNB15, DFNB72, DFNB95" ENSG00000179855 "GIPC PDZ domain containing family member 3" Q8TF64 19 3585478-3593541 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 16.2" "Cell type enhanced" "Detected in some" "Adipocytes: 10.2;Cone photoreceptor cells: 3.4;Endothelial cells: 6.2;Microglial cells: 2.7;Rod photoreceptor cells: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 3.4;skin cancer: 3.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067765 Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 66: Photoreceptor cells - Visual perception" Nucleoplasm "Nuclear bodies, Golgi apparatus" "HPA067765: " "unprognostic (1.77e-1)" "unprognostic (1.73e-1)" "unprognostic (5.13e-2)" "unprognostic (6.99e-2)" "unprognostic (1.22e-1)" "unprognostic (1.76e-2)" "unprognostic (1.41e-1)" "unprognostic (3.67e-3)" "unprognostic (4.76e-2)" "unprognostic (2.97e-1)" "unprognostic (5.06e-3)" "unprognostic (2.26e-2)" "unprognostic (1.51e-3)" "unprognostic (1.96e-2)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (9.06e-2)" GIT1 ENSG00000108262 "GIT ArfGAP 1" Q9Y2X7 17 29573475-29594054 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 128.8" "Cell type enhanced" "Detected in all" "Early spermatids: 101.4;Late spermatids: 96.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Lung - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004059, HPA004186" Enhanced Supported "Focal adhesion sites,Mitochondria,Cytosol" NA NA 36000 "Cluster 33: Non-specific - ATP binding" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 17 "Focal adhesion sites, Cytosol" Mitochondria "HPA004059: AB_1078966, HPA004186: AB_1078967" "unprognostic (3.66e-1)" "unprognostic (4.46e-2)" "unprognostic (3.24e-2)" "unprognostic (6.30e-3)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.00e-3)" "unprognostic (2.79e-1)" "unprognostic (5.23e-2)" "unprognostic (2.12e-2)" "unprognostic (3.08e-1)" "unprognostic (8.48e-2)" "unprognostic (5.56e-2)" "unprognostic (7.30e-2)" "unprognostic (2.10e-1)" "unprognostic (1.69e-1)" GNAZ ENSG00000128266 "G protein subunit alpha z" P19086 22 23070519-23125032 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.0" "Cell type enhanced" "Detected in many" "Adipocytes: 30.4;Basal prostatic cells: 17.7;Bipolar cells: 19.3;Cone photoreceptor cells: 28.9;Horizontal cells: 43.4;Rod photoreceptor cells: 26.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003011 Enhanced Approved Vesicles NA NA 180000 "Cluster 20: Non-specific - DNA binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 57: Platelets - Hemostasis" Vesicles "HPA003011: AB_1078918" "unprognostic (7.61e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (3.45e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-3)" "unprognostic (1.68e-2)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (6.63e-2)" "unprognostic (2.82e-1)" "unprognostic (1.30e-1)" GNG11 GNGT11 ENSG00000127920 "G protein subunit gamma 11" P61952 7 93921735-93928610 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Adipocytes: 1792.1;Endothelial cells: 1116.9;Lymphatic endothelial cells: 2285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 20.5;neutrophil: 9.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 20.5" "Cancer enhanced" "Detected in many" "Kidney cancer: 86.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045255 Uncertain NA NA 3400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Platelets - Hemostasis" 2 "HPA045255: AB_10794781" "unprognostic (1.30e-1)" "unprognostic (8.04e-2)" "unprognostic (2.53e-1)" "unprognostic (4.89e-3)" "unprognostic (4.94e-2)" "unprognostic (2.63e-2)" "unprognostic (2.58e-2)" "unprognostic (3.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.88e-1)" "unprognostic (1.42e-1)" "unprognostic (2.62e-2)" "unprognostic (1.91e-2)" "unprognostic (2.14e-3)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" "unprognostic (4.71e-3)" GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 106.8;parathyroid gland: 209.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 183.5;Paneth cells: 131.8;Proximal enterocytes: 348.1;Proximal tubular cells: 138.5;Undifferentiated cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 2 "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" GUCY1A1 "GC-SA3, GUC1A3, GUCY1A3" ENSG00000164116 "Guanylate cyclase 1 soluble subunit alpha 1" Q02108 4 155666726-155737059 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 125.4;Cardiomyocytes: 101.7;Inhibitory neurons: 68.3;Prostatic glandular cells: 170.2;Sertoli cells: 76.2;Smooth muscle cells: 146.2" "Cancer enhanced" "Detected in all" "prostate cancer: 24.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 8.3;non-classical monocyte: 10.1;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 35 "dendritic cells: 11.5;monocytes: 10.1;NK-cells: 8.3" "Cancer enhanced" "Detected in many" "prostate cancer: 29.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Endothelial cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010887, HPA056004, HPA058617" Uncertain Supported Nucleoplasm NA NA 7100 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 7: Adipose tissue - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 48: Smooth muscle cells - Signal transduction" 1 Nucleoplasm "CAB010887: AB_259901, HPA056004: AB_2683007, HPA058617: AB_2732624" "unprognostic (4.81e-3)" "unprognostic (2.60e-1)" "unprognostic (3.03e-1)" "unprognostic (2.15e-1)" "unprognostic (1.99e-2)" "unprognostic (7.77e-3)" "unprognostic (1.07e-1)" "prognostic favorable (2.38e-4)" "unprognostic (1.85e-3)" "unprognostic (6.46e-2)" "unprognostic (3.42e-2)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (2.27e-1)" "unprognostic (6.55e-3)" HDGFL3 "Hdgfrp3, HRP-3" ENSG00000166503 "HDGF like 3" Q9Y3E1 15 83112738-83207823 "Predicted intracellular proteins" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 207.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040719 Approved Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoplasm "HPA040719: AB_2677097" "unprognostic (1.28e-3)" "unprognostic (1.13e-1)" "unprognostic (3.52e-2)" "unprognostic (3.38e-2)" "unprognostic (1.53e-1)" "unprognostic (2.55e-2)" "unprognostic (1.91e-2)" "unprognostic (2.95e-2)" "unprognostic (2.99e-2)" "unprognostic (4.68e-2)" "unprognostic (1.93e-3)" "unprognostic (3.39e-2)" "unprognostic (1.73e-1)" "unprognostic (1.06e-2)" "unprognostic (3.55e-1)" "unprognostic (1.25e-1)" "unprognostic (1.85e-1)" HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0" "Cell type enhanced" "Detected in many" "Adipocytes: 100.2;Extravillous trophoblasts: 130.8;granulocytes: 94.4" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cancer enhanced" "Detected in many" "skin cancer: 35.0" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 6 Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" HIP1R "FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655" ENSG00000130787 "Huntingtin interacting protein 1 related" O75146 12 122834453-122862961 "Cancer-related genes, Predicted intracellular proteins" Endocytosis Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 127.6;Oligodendrocyte precursor cells: 158.5;Oligodendrocytes: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.3;naive B-cell: 10.6" "Group enriched" "Detected in many" 8 "B-cells: 10.6;granulocytes: 2.9;T-cells: 3.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017187, HPA038135, HPA038136" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 75: Serous glandular cells - Salivary secretion" "Plasma membrane, Cytosol" Vesicles "CAB017187: , HPA038135: AB_2675851, HPA038136: AB_2675852" "unprognostic (4.52e-1)" "unprognostic (6.39e-2)" "unprognostic (7.07e-2)" "unprognostic (6.55e-3)" "unprognostic (8.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.02e-2)" "unprognostic (8.11e-2)" "unprognostic (6.37e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.72e-2)" "prognostic favorable (6.50e-7)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (2.54e-3)" "prognostic favorable (7.26e-4)" HSPA12B "C20orf60, dJ1009E24.2" ENSG00000132622 "Heat shock protein family A (Hsp70) member 12B" Q96MM6 20 3732685-3753111 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 62.0;Endothelial cells: 42.7;Late spermatids: 16.7;Lymphatic endothelial cells: 49.7;Microglial cells: 14.3;Peritubular cells: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013659, HPA015639" Uncertain Approved Nucleoplasm NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 10 Nucleoplasm "HPA013659: AB_1234541, HPA015639: AB_1851192" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (1.30e-1)" "unprognostic (6.99e-2)" "unprognostic (4.53e-2)" "unprognostic (2.09e-1)" "unprognostic (1.21e-1)" "unprognostic (6.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.07e-2)" "unprognostic (6.45e-2)" "unprognostic (8.74e-2)" "unprognostic (2.61e-2)" "unprognostic (1.75e-2)" "unprognostic (1.47e-1)" "unprognostic (4.05e-1)" "unprognostic (1.66e-2)" ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 164.0" "Cell type enhanced" "Detected in many" "Adipocytes: 346.2;Endothelial cells: 215.8;Lymphatic endothelial cells: 85.3;monocytes: 149.0;NK-cells: 86.1;Plasma cells: 130.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 72.4;lymphoma: 56.2;Myeloma: 73.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 79.5;dendritic cells: 466.3;Endothelial cells: 81.2;Langerhans cells: 57.8;Oocytes: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2669.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2669.0" "Cancer enhanced" "Detected in many" "Leukemia: 20.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "HPA003539, CAB018374" Uncertain NA NA "Cluster 41: Basophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" 17 "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" INPP1 ENSG00000151689 "Inositol polyphosphate-1-phosphatase" P49441 2 190343570-190371665 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 531.8;Late spermatids: 919.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 96.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 96.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Lung - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036698, HPA036699" Supported Approved "Centriolar satellite,Cytosol" NA NA 31000 "Cluster 19: Eosinophils - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 11: Late spermatids - Unknown function" "Centriolar satellite" Cytosol "HPA036698: AB_10672226, HPA036699: AB_2675260" "unprognostic (1.08e-3)" "unprognostic (4.50e-3)" "unprognostic (3.87e-2)" "unprognostic (2.70e-1)" "unprognostic (7.85e-2)" "unprognostic (3.67e-3)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (2.96e-2)" "unprognostic (7.28e-2)" "unprognostic (2.41e-1)" "unprognostic (2.54e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "prognostic favorable (1.12e-5)" "prognostic favorable (5.70e-4)" ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.4" "Cell type enhanced" "Detected in many" "Adipocytes: 230.2;Endothelial cells: 109.9;Hepatocytes: 85.4;Lymphatic endothelial cells: 68.4;Smooth muscle cells: 140.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Pancreas - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain Approved "Endoplasmic reticulum" NA NA 6300000 "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Endoplasmic reticulum" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" ITGA6 CD49f ENSG00000091409 "Integrin subunit alpha 6" P23229 2 172427354-172506459 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 324.3;Basal keratinocytes: 228.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 144.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.5" "Group enriched" "Detected in many" 28 "granulocytes: 22.5;NK-cells: 7.3;T-cells: 12.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009009, HPA012696, HPA027582" Enhanced NA NA 3300000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "CAB009009: AB_2128038, HPA012696: AB_1851822, HPA027582: AB_10602606" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (2.59e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.19e-1)" "unprognostic (1.61e-3)" "unprognostic (9.34e-2)" "unprognostic (6.01e-2)" "unprognostic (1.85e-3)" "unprognostic (1.84e-1)" "prognostic favorable (2.35e-11)" "unprognostic (3.35e-2)" "unprognostic (3.32e-1)" "unprognostic (2.98e-2)" "unprognostic (1.21e-3)" JAG2 ENSG00000184916 "Jagged canonical Notch ligand 2" Q9Y219 14 105140982-105168824 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 50.3;Basal respiratory cells: 29.6;Breast myoepithelial cells: 30.2;Endothelial cells: 33.6;Salivary duct cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Prostate - Prostate basal glandular cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025481, HPA030636, HPA050567" Approved Supported Vesicles,Cytosol NA NA 370000 "Cluster 21: Testis - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Vesicles Cytosol "CAB025481: , HPA030636: AB_10602607, HPA050567: AB_2681178" "unprognostic (6.74e-2)" "unprognostic (4.49e-2)" "unprognostic (4.28e-2)" "unprognostic (6.97e-3)" "unprognostic (3.50e-1)" "unprognostic (2.13e-2)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.18e-2)" "unprognostic (2.62e-1)" "unprognostic (1.67e-2)" "unprognostic (9.19e-2)" "unprognostic (8.47e-3)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.39e-1)" "unprognostic (2.17e-1)" JCAD KIAA1462 ENSG00000165757 "Junctional cadherin 5 associated" Q9P266 10 30012803-30115494 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 101.2;Endothelial cells: 71.7;Granulosa cells: 55.5;Lymphatic endothelial cells: 50.8;Microglial cells: 61.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 23.0" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017956 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Vesicles, Cell Junctions" "HPA017956: AB_1852408" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (5.37e-2)" "unprognostic (8.07e-2)" "unprognostic (6.32e-2)" "unprognostic (7.09e-2)" "unprognostic (9.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (1.33e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (2.54e-4)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.34e-2)" KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124033369-124726325 "Cancer-related genes, Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.2" "Group enriched" "Detected in many" 5 "Excitatory neurons: 1386.1;Inhibitory neurons: 459.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 1.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells" "Low region specificity" "Detected in all" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol NA NA 83000 "Cluster 54: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 34: Neurons - Neuronal signaling" 2 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: AB_1850494" "unprognostic (2.54e-2)" "unprognostic (3.43e-1)" "unprognostic (2.08e-1)" "unprognostic (3.12e-4)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-2)" "unprognostic (8.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-3)" "unprognostic (5.58e-2)" "unprognostic (2.67e-1)" "unprognostic (3.70e-2)" "unprognostic (2.81e-3)" KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Adipocytes: 177.2;Endothelial cells: 90.8;Lymphatic endothelial cells: 212.4" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.2" "Group enriched" "Detected in many" 5 "NK-cells: 1.2;T-cells: 1.0" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 21.8" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" KIAA1217 "DKFZP761L0424, ETL4, SKT" ENSG00000120549 KIAA1217 Q5T5P2 10 23694746-24547848 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 104.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 587.2;Inhibitory neurons: 1202.9;Oligodendrocyte precursor cells: 240.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004941 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 69: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA004941: AB_2130659" "unprognostic (3.60e-2)" "unprognostic (7.55e-3)" "unprognostic (1.20e-1)" "unprognostic (2.73e-2)" "unprognostic (1.27e-1)" "unprognostic (4.45e-3)" "unprognostic (1.60e-3)" "unprognostic (2.03e-3)" "unprognostic (1.87e-2)" "unprognostic (4.62e-2)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.69e-1)" "unprognostic (1.84e-3)" "unprognostic (5.27e-2)" "unprognostic (2.44e-1)" "unprognostic (2.97e-1)" "unprognostic (1.22e-1)" KIF17 "KIAA1405, KIF17B, KIF3X, KLP-2, OSM-3" ENSG00000117245 "Kinesin family member 17" Q9P2E2 1 20664014-20718017 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 22.6" "Cell type enhanced" "Detected in some" "Adipocytes: 17.0;Early spermatids: 39.0;Endothelial cells: 13.6;Late spermatids: 80.9;Lymphatic endothelial cells: 14.0" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032085 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" "Nucleoplasm, Plasma membrane" "HPA032085: AB_10669917" "unprognostic (4.15e-3)" "unprognostic (8.60e-3)" "unprognostic (6.43e-2)" "unprognostic (1.12e-2)" "unprognostic (7.68e-2)" "unprognostic (3.70e-1)" "unprognostic (1.07e-2)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (1.08e-1)" "unprognostic (7.34e-3)" "unprognostic (8.73e-2)" "unprognostic (3.63e-3)" "unprognostic (1.08e-2)" "unprognostic (2.26e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-2)" KL KLA ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 124.2;parathyroid gland: 131.0" "Group enriched" "Detected in some" 4 "Prostatic glandular cells: 40.3;Proximal tubular cells: 107.5" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Region enriched" "Detected in many" 11 "choroid plexus: 102.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.0;Kidney cancer: 4.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.9;cerebral cortex: 7.1;hippocampal formation: 7.6;medulla oblongata: 4.3" "Secreted to blood" Hormone NA NA 510000 "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" KLHL5 ENSG00000109790 "Kelch like family member 5" Q96PQ7 4 39045039-39126857 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 179.1;Microglial cells: 181.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013958 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 8: Neurons - Neuronal signaling" 1 "HPA013958: AB_1852590" "unprognostic (6.02e-2)" "unprognostic (3.94e-1)" "unprognostic (3.92e-1)" "unprognostic (7.54e-3)" "unprognostic (5.35e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-2)" "unprognostic (3.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.10e-1)" "unprognostic (6.04e-2)" "unprognostic (2.87e-2)" "unprognostic (1.42e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-3)" LBR "DHCR14B, TDRD18" ENSG00000143815 "Lamin B receptor" Q14739 1 225401502-225428925 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "DNA-binding, Oxidoreductase, Receptor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 216.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049840, HPA062236" Enhanced Enhanced "Nuclear membrane" NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 74: Neutrophils - Degranulation" 4 "Nuclear membrane" "HPA049840: AB_2680908, HPA062236: AB_2684721" "unprognostic (2.57e-1)" "unprognostic (1.57e-1)" "unprognostic (2.14e-3)" "unprognostic (1.32e-2)" "unprognostic (7.96e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (7.30e-4)" "unprognostic (3.60e-2)" "unprognostic (1.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.08e-1)" "unprognostic (5.45e-1)" "unprognostic (8.32e-2)" "unprognostic (2.78e-1)" LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Excitatory neurons: 1271.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cancer enriched" "Detected in many" 6 "Bone cancer: 28.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 14: Non-specific - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 21 "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" LIMS2 "PINCH-2, PINCH2" ENSG00000072163 "LIM zinc finger domain containing 2" Q7Z4I7 2 127638381-127681786 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 492.9" "Cell type enhanced" "Detected in many" "Adipocytes: 114.7;Alveolar cells type 1: 56.5;Cardiomyocytes: 55.6;Endothelial cells: 114.2;Granulosa cells: 83.2;Peritubular cells: 48.2;Smooth muscle cells: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 22.6" "Group enriched" "Detected in many" 13 "B-cells: 22.6;T-cells: 10.7" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 20.6" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Smooth muscle cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058340 Enhanced Supported "Focal adhesion sites" NA NA "Cluster 18: Non-specific - Translation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "Focal adhesion sites" "HPA058340: AB_2683683" "unprognostic (2.51e-2)" "unprognostic (1.25e-1)" "unprognostic (5.82e-3)" "unprognostic (4.51e-2)" "unprognostic (9.25e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.53e-7)" "unprognostic (3.98e-2)" "unprognostic (3.73e-1)" "unprognostic (2.29e-1)" "unprognostic (3.78e-2)" "unprognostic (8.86e-2)" "unprognostic (3.33e-1)" "unprognostic (4.60e-3)" "unprognostic (3.64e-2)" "unprognostic (1.77e-1)" "unprognostic (4.00e-2)" LMO2 "RBTN2, RBTNL1, RHOM2, TTG2" ENSG00000135363 "LIM domain only 2" P25791 11 33858576-33892076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 106.9;Endothelial cells: 148.1;Erythroid cells: 85.5;Lymphatic endothelial cells: 231.4;monocytes: 148.3" "Cancer enhanced" "Detected in all" "glioma: 30.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "dendritic cells: 1.9;granulocytes: 1.5;monocytes: 1.7" "Group enriched" "Detected in many" 7 "Leukemia: 49.1;lymphoma: 18.5" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016258, HPA029285, HPA070901, HPA070910" Approved Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 61 Nucleoplasm "CAB016258: AB_2136572, HPA029285: AB_2672978, HPA070901: , HPA070910: " "unprognostic (1.60e-1)" "unprognostic (1.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.14e-3)" "prognostic favorable (3.12e-4)" "unprognostic (1.73e-3)" "unprognostic (8.95e-2)" "unprognostic (5.76e-2)" "unprognostic (7.86e-3)" "unprognostic (3.69e-1)" "unprognostic (7.10e-2)" "unprognostic (9.65e-2)" "unprognostic (3.90e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" LPCAT2 "AGPAT11, AYTL1, FLJ20481, LPLAT9, LysoPAFAT" ENSG00000087253 "Lysophosphatidylcholine acyltransferase 2" Q7L5N7 16 55509072-55586666 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 87.4;thyroid gland: 83.8" "Cell type enhanced" "Detected in many" "granulocytes: 146.7;Microglial cells: 214.7;monocytes: 126.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 23.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 151.7;eosinophil: 199.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 199.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007891, HPA008433" Enhanced Supported Supported "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 7 "Endoplasmic reticulum" "Lipid droplets" "HPA007891: AB_1845223, HPA008433: " "unprognostic (1.43e-1)" "unprognostic (2.44e-2)" "prognostic favorable (3.43e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.91e-1)" "unprognostic (9.65e-3)" "unprognostic (8.12e-3)" "unprognostic (3.26e-3)" "unprognostic (1.67e-1)" "unprognostic (7.97e-2)" "unprognostic (3.18e-3)" "unprognostic (9.16e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (3.53e-2)" LRCH1 "CHDC1, KIAA1016" ENSG00000136141 "Leucine rich repeats and calponin homology domain containing 1" Q9Y2L9 13 46553168-46753040 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 86.2;Inhibitory neurons: 112.8;Microglial cells: 175.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021536 Approved Approved "Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 19: Non-specific - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 1 "Actin filaments, Cytosol" Nucleoli "HPA021536: AB_1853258" "unprognostic (7.13e-3)" "prognostic unfavorable (6.24e-4)" "unprognostic (3.59e-2)" "unprognostic (8.93e-2)" "unprognostic (7.50e-2)" "unprognostic (1.37e-1)" "unprognostic (5.16e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (2.16e-1)" "prognostic unfavorable (5.75e-4)" "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.04e-4)" "unprognostic (2.87e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-1)" "unprognostic (1.98e-2)" LRRC8C AD158 ENSG00000171488 "Leucine rich repeat containing 8 VRAC subunit C" Q8TDW0 1 89633072-89769903 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 72.3;Excitatory neurons: 71.1;Inhibitory neurons: 95.1;Microglial cells: 177.1;Oligodendrocytes: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 9.0;monocytes: 6.6;T-cells: 11.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029347 Uncertain Uncertain "Golgi apparatus" No No "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 65: Neurons - Synaptic function" "Golgi apparatus" "HPA029347: AB_10601544" "unprognostic (2.61e-2)" "unprognostic (3.09e-2)" "unprognostic (3.83e-2)" "unprognostic (1.76e-2)" "unprognostic (3.32e-2)" "unprognostic (1.65e-2)" "unprognostic (5.02e-2)" "unprognostic (3.76e-3)" "unprognostic (4.28e-2)" "unprognostic (4.90e-3)" "unprognostic (5.32e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.78e-2)" "unprognostic (4.42e-2)" "unprognostic (1.94e-2)" "unprognostic (3.38e-2)" MAGI1 "AIP3, BAIAP1, BAP1, MAGI-1, TNRC19, WWP3" ENSG00000151276 "Membrane associated guanylate kinase, WW and PDZ domain containing 1" Q96QZ7 3 65353525-66038918 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 239.7;Excitatory neurons: 480.2;Inhibitory neurons: 778.0;Oligodendrocyte precursor cells: 345.7;Oligodendrocytes: 495.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031851, HPA031853, HPA077002" Supported Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 8: Neurons - Neuronal signaling" 2 "Cell Junctions" Nucleoplasm "HPA031851: AB_10599289, HPA031853: AB_10602095, HPA077002: " "unprognostic (5.00e-2)" "unprognostic (9.84e-2)" "unprognostic (6.00e-3)" "unprognostic (1.73e-3)" "unprognostic (1.64e-1)" "unprognostic (2.17e-2)" "unprognostic (1.46e-3)" "unprognostic (9.46e-3)" "unprognostic (8.59e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (2.05e-3)" "prognostic favorable (4.55e-8)" "unprognostic (3.51e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-2)" "unprognostic (8.03e-2)" MANSC1 "FLJ10298, LOH12CR3" ENSG00000111261 "MANSC domain containing 1" Q9H8J5 12 12326056-12350242 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 67.9" "Cell type enhanced" "Detected in many" "Serous glandular cells: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "neutrophil: 98.6" "Lineage enriched" "Detected in many" 39 "granulocytes: 98.6" "Cancer enriched" "Detected in many" 6 "Bile duct cancer: 134.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "HPA007955, HPA007956" Approved Approved "Golgi apparatus,Vesicles" NA NA 44000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" Vesicles "Golgi apparatus" "HPA007955: AB_1079306, HPA007956: AB_1079305" "unprognostic (5.41e-3)" "unprognostic (3.10e-2)" "unprognostic (1.24e-1)" "unprognostic (5.46e-3)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.63e-2)" "unprognostic (8.47e-2)" "unprognostic (9.18e-2)" "unprognostic (5.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.03e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.15e-2)" "unprognostic (4.46e-2)" "unprognostic (3.65e-1)" "unprognostic (1.03e-2)" MCF2L "ARHGEF14, DBS, KIAA0362, OST" ENSG00000126217 "MCF.2 cell line derived transforming sequence like" O15068 13 112894378-113099742 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 162.5" "Cell type enhanced" "Detected in many" "Adipocytes: 126.2;Bipolar cells: 61.9;Cone photoreceptor cells: 96.9;Endothelial cells: 65.6;Intestinal goblet cells: 70.9;Microglial cells: 88.6;Oligodendrocytes: 69.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 35.9" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Other NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "unprognostic (1.56e-1)" "unprognostic (2.53e-2)" "unprognostic (8.86e-3)" "prognostic favorable (6.01e-4)" "unprognostic (9.07e-2)" "unprognostic (3.91e-2)" "unprognostic (7.07e-2)" "unprognostic (3.02e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "prognostic favorable (4.36e-5)" "unprognostic (1.17e-1)" "prognostic favorable (9.14e-6)" "unprognostic (2.04e-2)" "unprognostic (1.28e-1)" "unprognostic (2.24e-1)" "prognostic favorable (2.63e-5)" MCTP1 FLJ22344 ENSG00000175471 "Multiple C2 and transmembrane domain containing 1" Q6DN14 5 94703690-95285094 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.8" "Cell type enhanced" "Detected in many" "Adipocytes: 111.4;Excitatory neurons: 493.2;Inhibitory neurons: 394.8;monocytes: 119.7;Oligodendrocyte precursor cells: 247.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 45 "basophil: 37.1;classical monocyte: 28.7;eosinophil: 13.3;intermediate monocyte: 41.4;myeloid DC: 22.3;neutrophil: 40.7;non-classical monocyte: 40.8;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 54 "dendritic cells: 22.3;granulocytes: 40.7;monocytes: 41.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075887 Approved "Golgi apparatus" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 65: Neurons - Synaptic function" "Golgi apparatus" "HPA075887: " "unprognostic (1.20e-2)" "unprognostic (6.70e-4)" "unprognostic (1.77e-2)" "unprognostic (1.03e-2)" "unprognostic (1.16e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (2.47e-2)" "unprognostic (1.86e-1)" "unprognostic (6.99e-2)" "unprognostic (5.31e-2)" "unprognostic (1.35e-1)" "unprognostic (1.91e-6)" "unprognostic (5.38e-2)" "unprognostic (3.65e-2)" "unprognostic (2.89e-3)" "unprognostic (4.43e-2)" MECOM "EVI1, KMT8E, MDS1, MDS1-EVI1, PRDM3" ENSG00000085276 "MDS1 and EVI1 complex locus" Q03112 3 169083499-169663775 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 71.4" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Collecting duct cells: 167.3;Gastric mucus-secreting cells: 116.1;Glandular and luminal cells: 132.1;Microglial cells: 331.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046537 Supported Supported "Nuclear speckles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 4 "Nuclear speckles" "HPA046537: AB_2679689" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (3.24e-3)" "unprognostic (7.29e-2)" "unprognostic (2.87e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (4.77e-3)" "unprognostic (1.53e-2)" "unprognostic (3.27e-3)" "prognostic unfavorable (2.59e-4)" "unprognostic (1.87e-1)" "unprognostic (2.60e-3)" "unprognostic (6.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.37e-3)" MEOX1 MOX1 ENSG00000005102 "Mesenchyme homeobox 1" P50221 17 43640389-43661922 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 34.8;breast: 25.3;heart muscle: 24.2" "Group enriched" "Detected in some" 8 "Adipocytes: 62.2;Endothelial cells: 36.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 6.9" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 4 "T-reg: 17.5" "Lineage enriched" "Detected in single" 48 "T-cells: 17.5" "Group enriched" "Detected in many" 6 "ovarian cancer: 14.0;Rhabdoid: 19.9;Sarcoma: 5.1;Uterine cancer: 11.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Lung - Fibroblast_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045214, HPA063788" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 78 Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA045214: AB_10959299, HPA063788: " "unprognostic (1.36e-3)" "unprognostic (2.15e-4)" "unprognostic (1.25e-1)" "unprognostic (2.58e-3)" "unprognostic (2.01e-2)" "unprognostic (5.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.55e-3)" "unprognostic (6.71e-2)" "unprognostic (2.64e-1)" "unprognostic (1.46e-1)" "unprognostic (9.36e-2)" "unprognostic (3.44e-6)" "unprognostic (2.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.82e-1)" "unprognostic (7.47e-3)" MFSD4A "DKFZp761N1114, FLJ25004, FLJ34577, MFSD4, SLC60A1, UNQ3064" ENSG00000174514 "Major facilitator superfamily domain containing 4A" Q8N468 1 205568885-205602918 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 33.3;kidney: 64.4;stomach 1: 129.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 107.3;Distal enterocytes: 44.1;Excitatory neurons: 46.6;Gastric mucus-secreting cells: 31.8;Glandular and luminal cells: 40.2;Intestinal goblet cells: 41.3;Ionocytes: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 4.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Kidney - Ascending Loop of Henle cells, Skin - Eccrine sweat gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 19.6;cerebellum: 25.5;cerebral cortex: 77.8;hippocampal formation: 43.0" HPA055407 Approved NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA055407: " "unprognostic (7.15e-4)" "prognostic favorable (7.54e-4)" "unprognostic (5.60e-2)" "unprognostic (1.38e-1)" "unprognostic (2.09e-1)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic favorable (4.59e-4)" "unprognostic (2.73e-2)" "unprognostic (1.65e-2)" "unprognostic (3.20e-2)" "unprognostic (6.97e-3)" "prognostic favorable (2.27e-13)" "unprognostic (1.58e-1)" "unprognostic (4.44e-2)" "unprognostic (5.75e-3)" "unprognostic (8.78e-2)" MFSD6 FLJ20160 ENSG00000151690 "Major facilitator superfamily domain containing 6" Q6ZSS7 2 190408355-190509205 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 83.4;Oligodendrocytes: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022274 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 80: Non-specific - Endocytosis" "Cluster 45: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 3: Basal prostatic cells - Lipid metabolism" 31 "Nucleoplasm, Cytosol" "HPA022274: AB_2142776" "unprognostic (9.47e-2)" "unprognostic (7.01e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-2)" "unprognostic (2.49e-1)" "unprognostic (4.13e-3)" "unprognostic (1.78e-2)" "unprognostic (3.08e-2)" "unprognostic (3.92e-1)" "unprognostic (3.77e-1)" "unprognostic (9.54e-2)" "unprognostic (2.08e-1)" "prognostic favorable (1.05e-4)" "unprognostic (3.46e-2)" "unprognostic (3.27e-1)" "unprognostic (9.14e-2)" "unprognostic (9.18e-2)" MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Adipocytes: 217.5;Endothelial cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 84000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697897-152724569 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.3" "Group enriched" "Detected in some" 4 "Adipocytes: 116.9;Endothelial cells: 129.5;Lymphatic endothelial cells: 132.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 246 "granulocytes: 30.7" "Cancer enhanced" "Detected in some" "Leukemia: 3.6;thyroid cancer: 5.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA 120000 "Cluster 22: Eosinophils - Transcription" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Nucleoplasm "Nuclear bodies, Vesicles" "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" MYO10 "KIAA0799, MyoX" ENSG00000145555 "Myosin X" Q9HD67 5 16661907-16936288 "Plasma proteins, Predicted intracellular proteins" Transport "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 150.5;Muller glia cells: 195.3;Syncytiotrophoblasts: 161.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "non-classical monocyte: 2.6" "Lineage enriched" "Detected in single" 5 "monocytes: 2.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015224, HPA024223" Enhanced Supported "Nucleoli rim,Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 10: Muller glia cells - Visual perception" 3 "Plasma membrane, Cytosol" "Nucleoli rim" "CAB015224: , HPA024223: AB_1854248" "unprognostic (1.13e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (7.63e-2)" "unprognostic (1.04e-1)" "unprognostic (4.43e-2)" "unprognostic (2.96e-2)" "unprognostic (4.40e-2)" "unprognostic (8.34e-2)" "unprognostic (2.51e-2)" "unprognostic (3.16e-2)" "unprognostic (8.42e-2)" "unprognostic (1.85e-1)" "prognostic favorable (2.75e-4)" "unprognostic (8.93e-2)" "unprognostic (9.86e-2)" "unprognostic (4.56e-2)" "unprognostic (1.84e-1)" MYO5C MGC74969 ENSG00000128833 "Myosin VC" Q9NQX4 15 52192322-52295804 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.0;Alveolar cells type 1: 106.5;Alveolar cells type 2: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020790, HPA032115, HPA032116" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" Cytosol Nucleoplasm "CAB020790: , HPA032115: AB_2674158, HPA032116: AB_2674159" "unprognostic (1.85e-1)" "unprognostic (1.29e-1)" "unprognostic (3.49e-2)" "prognostic favorable (5.18e-5)" "unprognostic (2.94e-1)" "unprognostic (4.01e-2)" "unprognostic (2.07e-1)" "unprognostic (1.53e-1)" "unprognostic (4.53e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-3)" "unprognostic (4.82e-2)" "prognostic favorable (2.47e-5)" "prognostic favorable (5.82e-4)" "unprognostic (9.15e-2)" "unprognostic (2.34e-1)" "unprognostic (2.32e-1)" MYO6 "DFNA22, DFNB37, KIAA0389" ENSG00000196586 "Myosin VI" Q9UM54 6 75749201-75919537 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Hearing, Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cardiomyopathy, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 271.6;Oligodendrocytes: 380.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 5.4;MAIT T-cell: 3.0;memory CD4 T-cell: 1.7;memory CD8 T-cell: 3.1;naive CD8 T-cell: 3.0;NK-cell: 2.9" "Group enriched" "Detected in many" 7 "NK-cells: 2.9;T-cells: 5.4" "Cancer enhanced" "Detected in all" "prostate cancer: 146.4" "Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010762, HPA035482, HPA035483" Enhanced Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Kidney - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 45: Non-specific - Mixed function" 3 Nucleoplasm "CAB010762: AB_477166, HPA035482: , HPA035483: AB_2674647" "unprognostic (6.29e-2)" "unprognostic (6.34e-2)" "unprognostic (3.63e-3)" "unprognostic (1.30e-1)" "unprognostic (8.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.41e-3)" "unprognostic (1.23e-2)" "unprognostic (1.23e-2)" "unprognostic (2.66e-2)" "unprognostic (7.78e-2)" "unprognostic (2.78e-2)" "prognostic favorable (1.27e-12)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (1.41e-1)" "unprognostic (2.49e-2)" NEDD4 "KIAA0093, MGC176705, NEDD4-1, RPF1" ENSG00000069869 "NEDD4 E3 ubiquitin protein ligase" P46934 15 55826922-55993660 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Neurogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 65.1;tongue: 55.8" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 40.0;Oligodendrocyte precursor cells: 65.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001991, HPA039883, CAB072833" Approved Approved Cytosol NA NA 6500 "Cluster 19: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 76: Oligodendrocyte precursor - Unknown function" 18 Cytosol "CAB001991: , CAB072833: , HPA039883: AB_10795683" "unprognostic (1.18e-1)" "unprognostic (2.10e-2)" "unprognostic (5.66e-3)" "unprognostic (1.15e-1)" "unprognostic (6.97e-2)" "unprognostic (2.23e-1)" "unprognostic (3.18e-3)" "prognostic unfavorable (5.14e-4)" "unprognostic (1.36e-2)" "unprognostic (1.62e-1)" "unprognostic (4.96e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (6.38e-3)" "unprognostic (2.98e-1)" "unprognostic (2.22e-1)" "unprognostic (2.35e-2)" NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641263-172691540 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 76.2;Distal enterocytes: 57.4;Endothelial cells: 48.6;Leydig cells: 54.7;Paneth cells: 37.2;Proximal enterocytes: 50.8;Smooth muscle cells: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported "Actin filaments,Cytosol" NA Yes "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 48: Smooth muscle cells - Signal transduction" Cytosol "Actin filaments" "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" NLK ENSG00000087095 "Nemo like kinase" Q9UBE8 17 28041737-28196381 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 76.2" "Cell type enhanced" "Detected in many" "Early spermatids: 129.5;Excitatory neurons: 305.2;Late spermatids: 408.7;Oligodendrocytes: 341.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 45 "basophil: 30.0" "Lineage enriched" "Detected in single" 45 "granulocytes: 30.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018192, HPA056511" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 11: Late spermatids - Unknown function" 11 Nucleoplasm "Nucleoli, Cell Junctions" "HPA018192: AB_1854525, HPA056511: AB_2683160" "unprognostic (7.19e-2)" "unprognostic (1.98e-1)" "unprognostic (5.54e-2)" "unprognostic (5.64e-3)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (2.59e-3)" "unprognostic (2.72e-2)" "unprognostic (4.23e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (5.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.92e-1)" "unprognostic (5.27e-2)" "unprognostic (6.57e-2)" NOL4L "C20orf112, C20orf113, dJ1184F4.2, dJ1184F4.4, DKFZP566G1424" ENSG00000197183 "Nucleolar protein 4 like" Q96MY1 20 32443059-32585333 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 48.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 107.0;Early spermatids: 121.8;Late spermatids: 170.5;Oocytes: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041768, HPA043600" Enhanced Enhanced Nucleoplasm NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 39: Retina & Testis - Cilium" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Leukemia - Hemostasis" "Cluster 63: Late spermatids - Spermatogenesis" 1 Nucleoplasm "HPA041768: AB_10964172, HPA043600: AB_10961001" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (4.03e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.10e-1)" "unprognostic (7.88e-2)" "unprognostic (2.75e-3)" "unprognostic (1.65e-2)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (3.88e-2)" "unprognostic (9.32e-2)" "unprognostic (3.42e-1)" "unprognostic (6.08e-3)" "prognostic favorable (2.63e-4)" NOSTRIN MGC20702 ENSG00000163072 "Nitric oxide synthase trafficking" Q8IVI9 2 168786539-168865514 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 150.9;Endothelial cells: 167.9;Serous glandular cells: 106.9;Sertoli cells: 65.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.4;Gastric cancer: 9.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044384, HPA076885" Approved Approved Vesicles,Cytosol NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 Cytosol Vesicles "HPA044384: AB_2678922, HPA076885: " "unprognostic (4.74e-2)" "unprognostic (2.42e-1)" "unprognostic (8.73e-2)" "unprognostic (2.27e-1)" "unprognostic (3.15e-3)" "unprognostic (3.02e-6)" "unprognostic (4.89e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-4)" "unprognostic (5.47e-3)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (2.33e-1)" "unprognostic (6.47e-2)" "unprognostic (4.98e-2)" NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Host-virus interaction, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.4" "Group enriched" "Detected in many" 4 "Adipocytes: 244.7;Endothelial cells: 119.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" NA NA 6400000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "unprognostic (2.27e-1)" "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (9.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.88e-2)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.13e-1)" NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Neurogenesis" RNA-binding "Autism spectrum disorder, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.6" "Cell type enhanced" "Detected in some" "Adipocytes: 38.6;Bipolar cells: 50.3;Endothelial cells: 32.7;Excitatory neurons: 21.0;Horizontal cells: 27.1;Inhibitory neurons: 20.1;Lymphatic endothelial cells: 28.0" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 11.5" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" NPDC1 "CAB-, CAB1, DKFZp586J0523" ENSG00000107281 "Neural proliferation, differentiation and control 1" Q9NQX5 9 137039463-137046179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 425.6;Endothelial cells: 321.0;Intestinal goblet cells: 603.5;Prostatic glandular cells: 360.6" "Cancer enhanced" "Detected in all" "prostate cancer: 146.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 12.3;MAIT T-cell: 14.7;memory CD4 T-cell: 19.1;memory CD8 T-cell: 18.9;T-reg: 15.9" "Lineage enriched" "Detected in many" 5 "T-cells: 19.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Prostate glandular cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008189 Approved Approved Nucleoplasm,Cytosol NA NA 240000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 27 Nucleoplasm Cytosol "HPA008189: AB_1854584" "unprognostic (6.94e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.01e-5)" "prognostic favorable (6.19e-5)" "unprognostic (2.06e-1)" "unprognostic (4.83e-3)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (8.65e-2)" "unprognostic (1.53e-1)" "prognostic favorable (3.18e-4)" "unprognostic (2.40e-1)" "unprognostic (2.65e-2)" "unprognostic (1.23e-2)" "unprognostic (2.35e-1)" "unprognostic (4.20e-2)" "unprognostic (8.84e-2)" NRARP MGC61598 ENSG00000198435 "NOTCH regulated ankyrin repeat protein" Q7Z6K4 9 137299631-137302271 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 46.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 245.8;Schwann cells: 358.8;Squamous epithelial cells: 188.4;Suprabasal keratinocytes: 447.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 51.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025729 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 12: Squamous epithelial cells - Keratinization" 1 Cytosol Nucleoplasm "HPA025729: AB_1854633" "unprognostic (9.92e-2)" "unprognostic (1.75e-2)" "unprognostic (1.56e-1)" "unprognostic (7.17e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-1)" "unprognostic (3.42e-2)" "unprognostic (1.89e-2)" "unprognostic (1.00e-2)" "unprognostic (6.42e-2)" "unprognostic (4.73e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (6.73e-6)" "unprognostic (2.85e-3)" "unprognostic (1.34e-1)" "unprognostic (4.90e-2)" "unprognostic (3.28e-3)" NRN1 NRN ENSG00000124785 "Neuritin 1" Q9NPD7 6 5997999-6007605 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 185.8" "Cell type enhanced" "Detected in many" "Adipocytes: 270.1;Endothelial cells: 121.8;Excitatory neurons: 69.6;Extravillous trophoblasts: 78.0;Lymphatic endothelial cells: 98.6;Schwann cells: 140.0" "Cancer enhanced" "Detected in all" "glioma: 38.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "MAIT T-cell: 2.6;neutrophil: 2.3" "Group enriched" "Detected in many" 7 "granulocytes: 2.3;T-cells: 2.6" "Cancer enhanced" "Detected in many" "Bone cancer: 90.3" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 23000 "Cluster 24: Non-specific - Transcription" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "unprognostic (6.24e-2)" "unprognostic (2.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (4.70e-3)" "unprognostic (2.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (1.67e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.79e-5)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" "unprognostic (4.37e-3)" NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 336.4;Endothelial cells: 161.7;Hofbauer cells: 118.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.4" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004511, HPA030278" Approved Uncertain Mitochondria "Secreted in other tissues" Receptor NA NA 780000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 Mitochondria "CAB004511: AB_2282634, HPA030278: AB_10601976" "unprognostic (3.19e-1)" "prognostic unfavorable (7.10e-5)" "unprognostic (1.50e-2)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (6.17e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (6.66e-2)" "unprognostic (2.52e-1)" "unprognostic (1.82e-1)" "unprognostic (4.78e-2)" "prognostic unfavorable (3.87e-4)" "prognostic unfavorable (1.22e-5)" "unprognostic (3.83e-2)" "unprognostic (5.48e-2)" "unprognostic (7.79e-2)" NTN4 ENSG00000074527 "Netrin 4" Q9HB63 12 95657807-95791189 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 176.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 180.9;Oligodendrocyte precursor cells: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "MAIT T-cell: 1.6" "Lineage enriched" "Detected in single" 16 "T-cells: 1.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049832 Approved "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 47: Spleen - Immune response" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 8 "HPA049832: AB_2680905" "unprognostic (3.08e-1)" "unprognostic (2.17e-1)" "unprognostic (2.33e-1)" "unprognostic (4.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" "unprognostic (1.67e-1)" "unprognostic (3.03e-2)" "unprognostic (8.71e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.50e-4)" "unprognostic (2.85e-1)" "prognostic favorable (8.12e-9)" "unprognostic (3.52e-2)" "unprognostic (7.08e-2)" "unprognostic (1.93e-1)" "prognostic favorable (6.67e-5)" PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 188.3;Distal enterocytes: 299.9;Intestinal goblet cells: 102.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 16 "B-cells: 8.1;dendritic cells: 4.0" "Cancer enhanced" "Detected in many" "Myeloma: 39.2" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 51: Thyroid gland - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 9: Endometrial stromal cells - Transcription" 1 "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" PCDH12 ENSG00000113555 "Protocadherin 12" Q9NPG4 5 141943581-141969741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Epilepsy, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 29.2" "Group enriched" "Detected in some" 4 "Adipocytes: 34.4;Endothelial cells: 25.7;Hofbauer cells: 32.4;Lymphatic endothelial cells: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 4.7" "Lineage enriched" "Detected in single" 41 "monocytes: 4.7" "Cancer enhanced" "Detected in some" "Myeloma: 3.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051242 Uncertain "Secreted to blood" "Cell adhesion" NA NA 14000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA051242: AB_2681402" "unprognostic (6.62e-2)" "unprognostic (6.94e-2)" "unprognostic (4.74e-3)" "unprognostic (4.12e-2)" "unprognostic (3.99e-1)" "unprognostic (3.25e-1)" "unprognostic (4.35e-1)" "unprognostic (1.88e-2)" "unprognostic (4.29e-2)" "unprognostic (2.76e-1)" "unprognostic (9.99e-2)" "unprognostic (3.87e-1)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.11e-2)" "unprognostic (5.21e-2)" "unprognostic (9.37e-2)" "unprognostic (9.33e-2)" PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.2;lung: 13.6;lymphoid tissue: 24.4" "Cell type enhanced" "Detected in many" "Astrocytes: 73.1;Early spermatids: 81.7;Endothelial cells: 110.7;Excitatory neurons: 120.7;Granulosa cells: 80.3;Inhibitory neurons: 65.0;Oligodendrocyte precursor cells: 181.1;Oligodendrocytes: 94.1;Spermatocytes: 59.0" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 11.2;Neuroblastoma: 6.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 34: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" PDE2A ENSG00000186642 "Phosphodiesterase 2A" O00408 11 72576141-72674591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 123.2;lymphoid tissue: 192.3" "Cell type enhanced" "Detected in many" "Adipocytes: 112.8;Endothelial cells: 71.1;Excitatory neurons: 67.8;Inhibitory neurons: 34.1;Lymphatic endothelial cells: 76.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 2.8;T-cells: 7.3" "Group enriched" "Detected in many" 4 "cervical cancer: 33.0;Neuroblastoma: 23.3" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 111.0;basal ganglia: 193.0;cerebral cortex: 119.4;hippocampal formation: 123.9" "CAB009752, HPA031192" Enhanced Supported Cytosol NA NA "Cluster 27: T-cells - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Cytosol "CAB009752: AB_2268159, HPA031192: AB_2673781" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (4.58e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (2.50e-1)" "prognostic favorable (1.76e-6)" "unprognostic (3.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.01e-3)" "unprognostic (3.13e-3)" "unprognostic (1.50e-2)" "unprognostic (1.77e-2)" "unprognostic (2.85e-3)" "unprognostic (6.31e-2)" "unprognostic (7.72e-2)" "unprognostic (7.96e-4)" PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 128.6;dendritic cells: 66.4;Endothelial cells: 69.3;Langerhans cells: 76.9;Macrophages: 52.8;Schwann cells: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Enteric glia cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" "Growth factor" NA NA 4390000 950000 "Cluster 1: T-cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Dendritic cells - Antigen presentation" 4 Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 439.6" "Cell type enhanced" "Detected in many" "Adipocytes: 681.6;Endothelial cells: 592.8;Lymphatic endothelial cells: 217.7;monocytes: 309.0;Plasma cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 706.3" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Leukemia: 41.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 58: Placenta - Pregnancy" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 58 "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" PITPNC1 "RDGB-BETA, RDGBB, RDGBB1" ENSG00000154217 "Phosphatidylinositol transfer protein cytoplasmic 1" Q9UKF7 17 67377281-67697256 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1191.2;Inhibitory neurons: 317.0;Oligodendrocyte precursor cells: 264.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026563, HPA031250" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 47: Astrocytes - Unknown function" 2 Cytosol Nucleoplasm "HPA026563: AB_1855409, HPA031250: AB_2673808" "unprognostic (1.33e-1)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.14e-3)" "unprognostic (4.17e-2)" "prognostic favorable (4.85e-5)" "unprognostic (6.57e-2)" "unprognostic (6.32e-3)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "unprognostic (5.70e-2)" "unprognostic (2.31e-2)" "unprognostic (1.34e-2)" "unprognostic (9.83e-2)" "unprognostic (7.88e-2)" "unprognostic (2.65e-3)" "unprognostic (1.16e-2)" PKD1L1 PRO19563 ENSG00000158683 "Polycystin 1 like 1, transient receptor potential channel interacting" Q8TDX9 7 47740202-47948466 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" Heterotaxy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Astrocytes: 12.7;Excitatory neurons: 24.8;Inhibitory neurons: 36.2;Late spermatids: 8.8;Microglial cells: 14.3;Oligodendrocyte precursor cells: 10.8;Oligodendrocytes: 15.9" "Cancer enhanced" "Detected in single" "testis cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Endothelial cells, Liver - Vascular Endothelial cells" "Not detected" "Not detected" "HPA020422, HPA022424" Uncertain NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 20: Myeloma - Immune response" "Cluster 69: Neurons - Neuronal signaling" "HPA020422: AB_1855434, HPA022424: AB_1855435" "unprognostic (5.47e-2)" "unprognostic (5.33e-3)" "unprognostic (1.49e-2)" "unprognostic (9.74e-2)" "unprognostic (4.03e-2)" "unprognostic (6.31e-2)" "unprognostic (2.52e-2)" "unprognostic (1.11e-1)" "unprognostic (9.63e-3)" "unprognostic (7.96e-2)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (1.88e-4)" "unprognostic (1.88e-3)" "unprognostic (2.56e-1)" "unprognostic (2.50e-1)" "unprognostic (1.90e-1)" PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702503-128720916 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 25.1;Breast glandular cells: 15.2;Endothelial cells: 20.4;Microglial cells: 12.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA045390, HPA058305" Uncertain Approved Vesicles NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Breast glandular cells - Lactation" 8 Vesicles "HPA045390: AB_2679308, HPA058305: AB_2683674" "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" PKP4 p0071 ENSG00000144283 "Plakophilin 4" Q99569 2 158456952-158682879 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 377.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 252.2;Inhibitory neurons: 250.2;Oligodendrocyte precursor cells: 220.7;Oligodendrocytes: 804.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037334, HPA066647, HPA070648" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Oligodendrocytes - Unknown function" 8 "Cell Junctions" "Plasma membrane" "CAB037334: , HPA066647: AB_2685696, HPA070648: AB_2686291" "unprognostic (2.76e-1)" "unprognostic (5.26e-2)" "unprognostic (1.48e-2)" "prognostic favorable (5.80e-4)" "unprognostic (2.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.43e-1)" "unprognostic (1.04e-2)" "unprognostic (9.53e-2)" "unprognostic (1.82e-2)" "unprognostic (9.69e-2)" "prognostic favorable (3.29e-7)" "unprognostic (2.23e-1)" "unprognostic (9.80e-2)" "unprognostic (1.33e-3)" "unprognostic (2.28e-3)" PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81779279-81962685 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0" "Cell type enhanced" "Detected in many" "B-cells: 83.1;Microglial cells: 91.3;NK-cells: 43.8;Plasma cells: 94.3" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 28.1;lymphoma: 88.4;Myeloma: 29.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Kidney - Intercalated cells, Liver - Hepatocytes, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 8200 "Cluster 14: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 11 "Vesicles, Cytosol" Nucleoplasm "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favorable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 27.9" "Group enriched" "Detected in many" 4 "Adipocytes: 85.5;Astrocytes: 93.5;B-cells: 57.8;Endothelial cells: 58.5;Lymphatic endothelial cells: 58.3;Microglial cells: 125.2;Oligodendrocytes: 156.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "memory B-cell: 22.9;naive B-cell: 21.7" "Lineage enriched" "Detected in single" 31 "B-cells: 22.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Sertoli cells" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 73: B-cells - B-cell function" Nucleoplasm "HPA027128: AB_2672124, HPA027319: AB_10600306, HPA028270: AB_10611388" "unprognostic (2.93e-1)" "unprognostic (3.44e-1)" "unprognostic (3.04e-3)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.80e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-3)" "unprognostic (3.63e-1)" "unprognostic (4.30e-2)" "unprognostic (3.83e-1)" "unprognostic (2.15e-2)" PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 423.1" "Group enriched" "Detected in many" 12 "Adipocytes: 454.6;Endothelial cells: 397.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 35.1" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Group enriched" "Detected in some" 15 "Leukemia: 10.7;lymphoma: 3.9;ovarian cancer: 6.0" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 51: Thyroid gland - Unknown function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" PPP1R13B "ASPP1, KIAA0771, p53BP2-like, p85" ENSG00000088808 "Protein phosphatase 1 regulatory subunit 13B" Q96KQ4 14 103733195-103847575 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 102.6;Inhibitory neurons: 101.6;Late spermatids: 79.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006394, CAB015454" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 78: Testis - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Breast glandular cells - Lactation" 54 Nucleoplasm Cytosol "CAB015454: AB_2252775, HPA006394: AB_1079668" "unprognostic (1.20e-1)" "unprognostic (8.61e-2)" "unprognostic (6.65e-2)" "unprognostic (1.45e-1)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (1.25e-2)" "prognostic favorable (1.41e-4)" "unprognostic (3.22e-3)" "unprognostic (5.13e-2)" "unprognostic (5.39e-2)" "unprognostic (1.62e-3)" "prognostic favorable (3.28e-11)" "unprognostic (1.68e-1)" "unprognostic (1.69e-1)" "unprognostic (1.97e-2)" "unprognostic (2.23e-1)" PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 680.6;Microglial cells: 115.4;Oligodendrocyte precursor cells: 396.2;Oligodendrocytes: 206.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Kidney cancer: 7.9;ovarian cancer: 2.9;Uterine cancer: 4.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 47: Astrocytes - Unknown function" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 70.8;Microglial cells: 255.9;NK-cells: 217.4;T-cells: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.2;MAIT T-cell: 91.4;memory CD4 T-cell: 88.5;memory CD8 T-cell: 136.2;naive CD4 T-cell: 107.8;naive CD8 T-cell: 104.9;NK-cell: 113.1;T-reg: 80.4" "Group enriched" "Detected in all" 13 "NK-cells: 113.1;T-cells: 136.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase non-receptor type 12" Q05209 7 77537295-77640069 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" NA NA 770000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 7: Adipose tissue - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 57: Platelets - Hemostasis" 8 "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 205.9;Endothelial cells: 225.5;Inhibitory neurons: 65.7;Lymphatic endothelial cells: 77.8;Microglial cells: 157.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" RAB3C ENSG00000152932 "RAB3C, member RAS oncogene family" Q96E17 5 58582221-58859394 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.8;brain: 33.0" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 98.7;Excitatory neurons: 135.9;Inhibitory neurons: 488.0;Oligodendrocyte precursor cells: 123.1" "Cancer enhanced" "Detected in some" "glioma: 1.0;pancreatic cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 6.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003160, HPA048156" Enhanced Approved Cytosol NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" 7 Cytosol "HPA003160: AB_1079731, HPA048156: AB_2680291" "unprognostic (1.30e-1)" "unprognostic (3.35e-2)" "unprognostic (9.94e-2)" "unprognostic (2.23e-2)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (8.73e-3)" "unprognostic (3.40e-2)" "unprognostic (6.90e-2)" "unprognostic (7.58e-2)" "unprognostic (9.52e-4)" "unprognostic (1.51e-3)" "unprognostic (3.70e-5)" "unprognostic (4.70e-2)" "unprognostic (1.05e-1)" "unprognostic (9.65e-2)" "unprognostic (3.61e-3)" RAPGEF3 "bcm910, cAMP-GEFI, EPAC" ENSG00000079337 "Rap guanine nucleotide exchange factor 3" O95398 12 47734363-47771040 "Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 123.8;Astrocytes: 135.6;Collecting duct cells: 64.2;Endothelial cells: 60.1;Oligodendrocytes: 42.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 44.3" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004386, HPA040365, HPA043518" Approved Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Cytosol "Endoplasmic reticulum" "CAB004386: AB_627521, HPA040365: AB_2676941, HPA043518: AB_2678524" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (2.99e-2)" "unprognostic (1.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-2)" "unprognostic (1.23e-4)" "unprognostic (9.35e-2)" "unprognostic (1.25e-2)" "unprognostic (5.32e-3)" "unprognostic (4.67e-2)" "unprognostic (4.37e-2)" "prognostic favorable (6.67e-7)" "unprognostic (9.16e-2)" "unprognostic (2.92e-1)" "unprognostic (2.61e-3)" "unprognostic (3.38e-2)" RAPGEF5 "GFR, KIAA0277, MR-GEF" ENSG00000136237 "Rap guanine nucleotide exchange factor 5" Q92565 7 22118236-22357154 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 161.1;parathyroid gland: 375.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 488.2;Inhibitory neurons: 186.2;Microglial cells: 132.4;Oligodendrocytes: 596.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057821, HPA076772" Uncertain Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Other NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 51: Oligodendrocytes - Unknown function" Nucleoplasm "Nuclear bodies" "HPA057821: AB_2683538, HPA076772: AB_2686814" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (5.22e-2)" "prognostic favorable (3.52e-5)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" "unprognostic (1.31e-1)" "unprognostic (3.76e-2)" "unprognostic (6.36e-3)" "unprognostic (6.57e-2)" "unprognostic (2.55e-1)" "unprognostic (8.26e-3)" RASAL2 nGAP ENSG00000075391 "RAS protein activator like 2" Q9UJF2 1 178094104-178484147 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 488.7;Inhibitory neurons: 382.2;Microglial cells: 259.4;Rod photoreceptor cells: 184.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Lung - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018805, HPA020453" Enhanced Approved "Plasma membrane,Focal adhesion sites" NA Yes "Cluster 39: Retina & Testis - Cilium" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" 4 "Plasma membrane, Focal adhesion sites" "HPA018805: AB_1856085, HPA020453: AB_1856086" "unprognostic (5.55e-3)" "unprognostic (6.49e-2)" "unprognostic (2.65e-1)" "unprognostic (6.33e-2)" "unprognostic (3.40e-2)" "unprognostic (5.59e-2)" "unprognostic (5.91e-2)" "unprognostic (1.72e-2)" "unprognostic (2.91e-1)" "unprognostic (2.92e-2)" "unprognostic (3.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-2)" "unprognostic (4.98e-2)" "unprognostic (2.45e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (2.05e-4)" RASGRF2 "GRF2, Ras-GRF2" ENSG00000113319 "Ras protein specific guanine nucleotide releasing factor 2" O14827 5 80960363-81230162 "Predicted intracellular proteins, RAS pathway related proteins" "Calmodulin-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 213.7;Inhibitory neurons: 390.7;Microglial cells: 85.0;Oligodendrocytes: 368.2;Oocytes: 164.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 1.9;MAIT T-cell: 5.2;memory CD4 T-cell: 2.6;memory CD8 T-cell: 1.5;naive CD4 T-cell: 4.2;naive CD8 T-cell: 3.0" "Lineage enriched" "Detected in single" 52 "T-cells: 5.2" "Cancer enhanced" "Detected in many" "testis cancer: 14.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Pancreas - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018679 Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 8: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA018679: AB_1856089" "unprognostic (1.32e-1)" "unprognostic (6.96e-2)" "unprognostic (7.27e-2)" "unprognostic (7.80e-2)" "unprognostic (3.62e-1)" "unprognostic (1.00e-1)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (4.02e-1)" "unprognostic (8.51e-2)" "unprognostic (8.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.47e-3)" "unprognostic (1.37e-3)" "unprognostic (2.13e-2)" "unprognostic (5.01e-2)" "unprognostic (1.12e-1)" RASGRP3 "CalDAG-GEFIII, GRP3, KIAA0846" ENSG00000152689 "RAS guanyl releasing protein 3" Q8IV61 2 33436324-33564750 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.6;skeletal muscle: 40.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 56.4;Exocrine glandular cells: 72.2;Lymphatic endothelial cells: 103.4;Oligodendrocytes: 173.6;Plasma cells: 66.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 17 "basophil: 13.4;memory B-cell: 12.3;naive B-cell: 15.1" "Group enriched" "Detected in many" 18 "B-cells: 15.1;granulocytes: 13.4" "Group enriched" "Detected in many" 6 "lymphoma: 53.5;Myeloma: 43.2" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039136 Approved "Golgi apparatus,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 3 Cytosol "Golgi apparatus" "HPA039136: " "unprognostic (2.64e-1)" "unprognostic (9.50e-2)" "unprognostic (1.45e-1)" "unprognostic (5.76e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (3.90e-1)" "unprognostic (7.57e-2)" "unprognostic (2.39e-2)" "unprognostic (4.35e-2)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (9.96e-3)" "unprognostic (1.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.87e-1)" "unprognostic (5.82e-2)" RASIP1 "FLJ20401, RAIN" ENSG00000105538 "Ras interacting protein 1" Q5U651 19 48720585-48740610 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 112.8;Endothelial cells: 91.9;Lymphatic endothelial cells: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 19.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077251 Approved NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA077251: AB_2732337" "unprognostic (9.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-2)" "prognostic favorable (7.17e-5)" "unprognostic (8.44e-2)" "unprognostic (2.63e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.46e-4)" "unprognostic (5.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" RB1 "OSRC, PPP1R130, RB" ENSG00000139687 "RB transcriptional corepressor 1" P06400 13 48303744-48599436 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 250.2;Melanocytes: 278.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000095, CAB016687, HPA050082" Supported Supported Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" 36 Nucleoplasm "CAB000095: , CAB016687: AB_1622010, HPA050082: AB_2681008" "unprognostic (4.24e-3)" "unprognostic (1.00e-1)" "unprognostic (3.62e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-2)" "unprognostic (3.86e-1)" "unprognostic (4.69e-2)" "unprognostic (7.08e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (6.92e-4)" "unprognostic (4.06e-2)" "unprognostic (9.40e-2)" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (9.99e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" RBP7 CRBPIV ENSG00000162444 "Retinol binding protein 7" Q96R05 1 9997206-10016021 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 388.2;breast: 381.7" "Cell type enriched" "Detected in many" 7 "Adipocytes: 3296.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 312.6;neutrophil: 347.3" "Group enriched" "Detected in many" 31 "granulocytes: 347.3;monocytes: 312.6" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 99.4" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA034749 Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Nuclear speckles, Cytosol" "HPA034749: AB_10602084" "unprognostic (1.93e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (9.59e-2)" "unprognostic (2.31e-1)" "unprognostic (6.28e-2)" "unprognostic (1.39e-2)" "unprognostic (1.85e-1)" "unprognostic (1.05e-3)" "unprognostic (2.24e-1)" "unprognostic (1.46e-2)" "unprognostic (7.90e-2)" "unprognostic (5.07e-2)" "unprognostic (2.38e-2)" "unprognostic (2.93e-1)" "unprognostic (1.15e-1)" "unprognostic (1.61e-2)" RGS6 ENSG00000182732 "Regulator of G protein signaling 6" P49758 14 71932429-72566530 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;heart muscle: 10.8;testis: 10.2" "Cell type enhanced" "Detected in many" "Astrocytes: 92.3;Early spermatids: 101.0;Excitatory neurons: 632.0;Inhibitory neurons: 244.4;Late spermatids: 323.8" "Group enriched" "Detected in some" 7 "glioma: 3.1;thyroid cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 5.5" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003067 Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 24: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" 1 Nucleoplasm "Nucleoli, Vesicles" "HPA003067: AB_1079807" "unprognostic (7.18e-2)" "unprognostic (7.78e-2)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (5.61e-2)" "unprognostic (3.80e-2)" "unprognostic (1.24e-4)" "unprognostic (7.83e-2)" "unprognostic (2.03e-1)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.06e-2)" "unprognostic (8.64e-2)" "unprognostic (5.11e-2)" "unprognostic (8.06e-3)" "unprognostic (2.10e-1)" "unprognostic (3.68e-2)" RIPOR1 "FAM65A, FLJ13725" ENSG00000039523 "RHO family interacting cell polarization regulator 1" Q6ZS17 16 67518418-67546788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 11.2;eosinophil: 9.4;intermediate monocyte: 15.6;memory B-cell: 15.9;myeloid DC: 10.2;naive B-cell: 9.5;neutrophil: 6.6;non-classical monocyte: 15.2;plasmacytoid DC: 14.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Lung - Endothelial cells, Testis - Sertoli cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005923 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Golgi apparatus, Cytosol" "HPA005923: AB_1078809" "unprognostic (7.41e-2)" "unprognostic (2.07e-2)" "unprognostic (1.56e-3)" "unprognostic (3.71e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.10e-2)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.38e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.82e-8)" "unprognostic (8.51e-2)" "unprognostic (3.52e-2)" "unprognostic (1.19e-1)" "unprognostic (7.46e-2)" RNF180 ENSG00000164197 "Ring finger protein 180" Q86T96 5 64165843-64372869 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 24.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 87.4;Inhibitory neurons: 145.2;Oligodendrocyte precursor cells: 152.3" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006897 Approved Approved Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 51: Thyroid gland - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" Cytosol "HPA006897: AB_1856348" "unprognostic (7.46e-2)" "unprognostic (3.90e-3)" "unprognostic (3.19e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (2.72e-1)" "unprognostic (5.57e-2)" "unprognostic (2.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.69e-1)" "unprognostic (3.37e-3)" "unprognostic (3.68e-2)" "prognostic favorable (6.81e-5)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.81e-2)" "unprognostic (9.81e-3)" ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Adipocytes: 171.6;Endothelial cells: 112.8;Lymphatic endothelial cells: 146.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 257.8;Endothelial cells: 150.8;Lymphatic endothelial cells: 76.8;NK-cells: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1252.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" SCARF1 "KIAA0149, SREC, SREC1" ENSG00000074660 "Scavenger receptor class F member 1" Q14162 17 1633858-1645744 "Predicted intracellular proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.0" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Endothelial cells: 46.2;Langerhans cells: 44.6;Lymphatic endothelial cells: 44.5;Microglial cells: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 3.1" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035108, HPA072936" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Receptor NA NA 2000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 18 "Golgi apparatus" "HPA035108: AB_10670289, HPA072936: AB_2686559" "unprognostic (1.94e-1)" "unprognostic (2.84e-1)" "unprognostic (2.53e-3)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-2)" "unprognostic (3.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.13e-2)" "unprognostic (3.22e-2)" "unprognostic (1.38e-1)" "unprognostic (6.39e-2)" SEC14L1 "PRELID4A, SEC14L" ENSG00000129657 "SEC14 like lipid binding 1" Q92503 17 77088749-77217101 "Plasma proteins, Predicted intracellular proteins, Transporters" "Immunity, Innate immunity" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 409.9;Late spermatids: 751.8;monocytes: 534.7;Plasma cells: 274.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 356.6" "Lineage enriched" "Detected in all" 11 "granulocytes: 356.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021463, HPA028703" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "Nucleoplasm, Cytosol" "HPA021463: AB_2670712, HPA028703: AB_10602300" "unprognostic (1.19e-1)" "unprognostic (8.61e-2)" "unprognostic (1.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-2)" "unprognostic (1.21e-1)" "unprognostic (7.40e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (1.37e-1)" "unprognostic (1.33e-3)" "unprognostic (3.09e-1)" "unprognostic (4.30e-2)" SEMA3F "Sema4, SEMAK" ENSG00000001617 "Semaphorin 3F" Q13275 3 50155045-50189075 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 97.9" "Cell type enhanced" "Detected in many" "Adipocytes: 38.2;Basal prostatic cells: 33.1;Bipolar cells: 23.9;Endothelial cells: 26.5;Suprabasal keratinocytes: 34.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 84.1" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035008 Approved "Secreted to blood" "Developmental protein" NA NA 1700000 7900000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA035008: AB_10604091" "unprognostic (8.17e-2)" "unprognostic (2.01e-1)" "unprognostic (1.12e-2)" "unprognostic (1.87e-2)" "unprognostic (5.52e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.71e-1)" "unprognostic (9.05e-2)" "unprognostic (4.20e-1)" "unprognostic (9.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.23e-2)" "unprognostic (6.19e-2)" "unprognostic (8.56e-2)" "unprognostic (3.88e-3)" "unprognostic (6.87e-3)" SEMA3G "FLJ00014, sem2" ENSG00000010319 "Semaphorin 3G" Q9NS98 3 52433035-52445103 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 77.5;breast: 62.1" "Cell type enriched" "Detected in some" 5 "Adipocytes: 136.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "T-reg: 1.4" "Lineage enriched" "Detected in single" 15 "T-cells: 1.4" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001761 Uncertain "Secreted to blood" "Developmental protein" NA NA 5600000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "HPA001761: AB_1079902" "unprognostic (2.10e-2)" "unprognostic (1.49e-1)" "unprognostic (7.08e-2)" "unprognostic (1.47e-2)" "unprognostic (2.85e-1)" "unprognostic (5.79e-4)" "unprognostic (5.20e-3)" "unprognostic (9.14e-2)" "unprognostic (5.54e-2)" "unprognostic (5.64e-2)" "unprognostic (1.34e-3)" "unprognostic (4.14e-1)" "prognostic favorable (8.86e-5)" "unprognostic (5.63e-2)" "unprognostic (2.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" SH2B3 "IDDM20, LNK" ENSG00000111252 "SH2B adaptor protein 3" Q9UQQ2 12 111405923-111451623 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 60.0" "Cell type enhanced" "Detected in many" "dendritic cells: 213.2;Kupffer cells: 103.4;Langerhans cells: 141.4;Macrophages: 97.7;monocytes: 150.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005483 Approved Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Dendritic cells - Antigen presentation" Nucleoplasm "HPA005483: AB_1079260" "unprognostic (2.77e-1)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.09e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.18e-1)" "unprognostic (4.65e-2)" "unprognostic (8.17e-3)" "unprognostic (9.08e-2)" "prognostic unfavorable (6.20e-4)" "unprognostic (2.86e-1)" "unprognostic (3.89e-3)" "unprognostic (1.11e-1)" "unprognostic (2.24e-2)" SH2D3C NSP3 ENSG00000095370 "SH2 domain containing 3C" Q8N5H7 9 127738317-127778710 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 47.9;dendritic cells: 35.5;Endothelial cells: 49.3;Lymphatic endothelial cells: 60.8;monocytes: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 13 "Leukemia: 34.2;lymphoma: 24.0;Myeloma: 27.0;Neuroblastoma: 15.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047586 Enhanced Supported Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 Cytosol "HPA047586: AB_2680093" "unprognostic (8.33e-2)" "unprognostic (4.77e-3)" "unprognostic (3.28e-2)" "prognostic favorable (9.47e-4)" "unprognostic (5.23e-2)" "prognostic favorable (1.98e-4)" "unprognostic (3.75e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.88e-3)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (5.28e-2)" SH3BGRL2 ENSG00000198478 "SH3 domain binding glutamate rich protein like 2" Q9UJC5 6 79631329-79703655 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 157.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.8;Intestinal goblet cells: 99.8;Serous glandular cells: 123.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 50.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 11.0" "Lineage enriched" "Detected in many" 10 "granulocytes: 11.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 34.5" "Adipose visceral - Endothelial cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047486 Approved Supported Nucleoplasm NA NA 2000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" Nucleoplasm "HPA047486: AB_2680065" "unprognostic (3.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.75e-2)" "unprognostic (2.28e-2)" "unprognostic (4.21e-1)" "unprognostic (7.77e-2)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (6.92e-2)" "unprognostic (6.53e-3)" "unprognostic (2.78e-1)" "unprognostic (7.94e-2)" "prognostic favorable (2.24e-4)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.33e-1)" SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733212 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 84.2" "Cell type enhanced" "Detected in many" "Adipocytes: 170.6;Endothelial cells: 73.1;Excitatory neurons: 27.4;Lymphatic endothelial cells: 29.9;Microglial cells: 42.0;Oligodendrocytes: 29.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" SHE ENSG00000169291 "Src homology 2 domain containing E" Q5VZ18 1 154469772-154502412 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 52.9;Alveolar cells type 1: 21.5;Endothelial cells: 75.5;Kupffer cells: 23.4;Lymphatic endothelial cells: 44.2;Microglial cells: 25.0;Spermatocytes: 26.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037417 Approved Approved Nucleoplasm,Cytosol "Secreted - unknown location" "No annotated function" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 11: Neuronal - Sensory perception" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Nucleoplasm Cytosol "HPA037417: AB_10672384" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (7.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.80e-1)" "unprognostic (6.80e-3)" "unprognostic (7.24e-2)" "unprognostic (3.07e-3)" "unprognostic (3.10e-2)" "unprognostic (8.22e-2)" "unprognostic (4.04e-2)" "unprognostic (8.29e-2)" "unprognostic (2.40e-2)" "unprognostic (7.31e-2)" "unprognostic (1.62e-1)" "unprognostic (3.33e-3)" "unprognostic (1.33e-2)" SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50586796-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 118.9;Oligodendrocytes: 431.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 4.6" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" SLC12A2 "BSC-2, BSC2, CCC1, NKCC1, PPP1R141" ENSG00000064651 "Solute carrier family 12 member 2" P55011 5 128083766-128189677 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Deafness, Disease variant, FDA approved drug targets, Intellectual disability, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 73.5" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 371.8;Oligodendrocytes: 527.4;Undifferentiated cells: 348.4" "Cancer enhanced" "Detected in all" "colorectal cancer: 54.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "colorectal cancer: 106.3" "Adipose visceral - Endothelial cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020130, HPA063697" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Vesicles, Plasma membrane" "HPA020130: AB_1854502, HPA063697: AB_2685094" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (4.20e-3)" "prognostic favorable (8.60e-4)" "unprognostic (3.99e-1)" "unprognostic (5.65e-3)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (3.30e-1)" "unprognostic (2.95e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.79e-1)" "unprognostic (3.88e-3)" SLC16A14 "FLJ30794, MCT14" ENSG00000163053 "Solute carrier family 16 member 14" Q7RTX9 2 230034982-230068993 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.0" "Cell type enhanced" "Detected in many" "Adipocytes: 16.2;Excitatory neurons: 17.9;Inhibitory neurons: 20.2;Microglial cells: 42.9;Oligodendrocyte precursor cells: 12.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "eosinophil: 11.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 11.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 21.7" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040518 Uncertain Approved "Endoplasmic reticulum" No No "Cluster 22: Eosinophils - Transcription" "Cluster 80: Non-specific - Endocytosis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Endoplasmic reticulum" "HPA040518: AB_10794877" "unprognostic (2.99e-1)" "unprognostic (1.74e-1)" "unprognostic (2.63e-1)" "unprognostic (1.74e-3)" "unprognostic (2.20e-3)" "unprognostic (2.01e-1)" "unprognostic (4.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.15e-1)" "unprognostic (5.70e-3)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.03e-3)" "unprognostic (3.51e-1)" "unprognostic (2.39e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 135.9;placenta: 99.0" "Group enriched" "Detected in many" 8 "Cytotrophoblasts: 1246.5;Syncytiotrophoblasts: 745.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" 35 "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: AB_10674985" "unprognostic (2.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.96e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.01e-1)" "unprognostic (1.63e-3)" "unprognostic (6.26e-2)" "unprognostic (7.48e-2)" "unprognostic (9.11e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.46e-1)" "prognostic favorable (2.24e-4)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-1)" SPAAR "LINC00961, SPAR" ENSG00000235387 "Small regulatory polypeptide of amino acid response" A0A1B0GVQ0 9 35909490-35937153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.0;breast: 10.5" "Cell type enhanced" "Detected in some" "Adipocytes: 37.7;Alveolar cells type 1: 6.6;Endothelial cells: 15.1;Oocytes: 7.4" "Cancer enhanced" "Detected in many" "renal cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 11.4;Sarcoma: 4.1" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "unprognostic (3.17e-1)" "unprognostic (2.19e-2)" "unprognostic (1.91e-2)" "unprognostic (7.00e-3)" "unprognostic (4.23e-2)" "unprognostic (2.61e-3)" "unprognostic (6.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.40e-3)" "unprognostic (3.17e-1)" "unprognostic (1.01e-1)" "unprognostic (7.72e-2)" "unprognostic (7.12e-3)" "unprognostic (1.67e-2)" "unprognostic (3.04e-1)" "unprognostic (1.27e-1)" "unprognostic (3.22e-1)" SPTLC2 "hLCB2a, KIAA0526, LCB2, LCB2A" ENSG00000100596 "Serine palmitoyltransferase long chain base subunit 2" O15270 14 77505997-77616637 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 118.9;monocytes: 141.6;Oligodendrocytes: 152.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075143 Approved "Plasma membrane,Cell Junctions" NA No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "Cell Junctions" "HPA075143: " "unprognostic (3.16e-1)" "unprognostic (2.82e-2)" "unprognostic (1.24e-1)" "unprognostic (4.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (1.46e-2)" "unprognostic (3.09e-1)" "unprognostic (4.05e-1)" "unprognostic (1.98e-2)" "unprognostic (2.51e-1)" "prognostic favorable (6.69e-8)" "unprognostic (1.29e-2)" "unprognostic (2.35e-1)" "unprognostic (4.94e-2)" "unprognostic (1.32e-1)" ST6GALNAC3 SIAT7C ENSG00000184005 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3" Q8NDV1 1 76074746-76634603 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Microglial cells: 871.4;Oligodendrocytes: 650.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Neuroblastoma: 13.8;skin cancer: 12.1;testis cancer: 7.6;thyroid cancer: 3.6" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Podocytes, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054566, HPA055399" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 51: Oligodendrocytes - Unknown function" 1 Nucleoplasm "HPA054566: AB_2682526, HPA055399: AB_2682806" "unprognostic (7.85e-2)" "unprognostic (1.78e-1)" "unprognostic (2.99e-2)" "unprognostic (2.70e-4)" "unprognostic (2.76e-2)" "unprognostic (2.21e-2)" "unprognostic (6.55e-3)" "unprognostic (7.31e-2)" "unprognostic (2.14e-1)" "unprognostic (4.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.95e-2)" "unprognostic (9.97e-4)" "unprognostic (3.33e-4)" "unprognostic (5.44e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-4)" SV2B "HsT19680, KIAA0735" ENSG00000185518 "Synaptic vesicle glycoprotein 2B" Q7L1I2 15 91099950-91302565 "Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 28.2;retina: 54.6" "Group enriched" "Detected in some" 5 "Bipolar cells: 130.3;Cone photoreceptor cells: 146.1;Excitatory neurons: 439.8;Rod photoreceptor cells: 144.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.6;lung cancer: 1.0" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046247 Approved NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 2 "HPA046247: AB_10963538" "unprognostic (2.92e-1)" "unprognostic (7.92e-2)" "unprognostic (1.32e-3)" "unprognostic (4.01e-5)" "unprognostic (2.66e-3)" "unprognostic (7.77e-2)" "unprognostic (3.36e-2)" "unprognostic (1.01e-1)" "unprognostic (3.57e-2)" "unprognostic (9.89e-2)" "unprognostic (1.20e-2)" "unprognostic (2.49e-1)" "unprognostic (1.39e-1)" "unprognostic (3.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-2)" "unprognostic (3.10e-4)" SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 146.2;B-cells: 205.5;Endothelial cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.5;naive B-cell: 84.7" "Group enriched" "Detected in all" 7 "B-cells: 84.7;granulocytes: 48.5;monocytes: 29.6" "Cancer enhanced" "Detected in all" "lymphoma: 134.6" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 3 "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" TANC1 "KIAA1728, ROLSB" ENSG00000115183 "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1" Q9C0D5 2 158968640-159232659 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 152.1;Oligodendrocyte precursor cells: 181.6;Oligodendrocytes: 208.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036750 Approved NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "HPA036750: AB_10670241" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" "unprognostic (1.56e-1)" "unprognostic (8.91e-2)" "unprognostic (2.43e-2)" "unprognostic (3.96e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.43e-2)" "unprognostic (3.94e-2)" "unprognostic (1.69e-2)" "unprognostic (1.20e-1)" "unprognostic (7.43e-2)" "unprognostic (3.07e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.12e-1)" TAOK2 "hKFC-C, KIAA0881, MAP3K17, PSK, PSK-1, PSK1, PSK1-BETA, TAO1, TAO2, Tao2beta" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973868-29992261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 49.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010650 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Nucleoplasm, Cytosol" Nucleoli "HPA010650: AB_1080204" "unprognostic (7.30e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.51e-4)" "prognostic favorable (3.87e-5)" "unprognostic (8.46e-2)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-1)" "prognostic favorable (4.78e-4)" "unprognostic (3.85e-3)" "prognostic favorable (3.66e-4)" "unprognostic (7.42e-3)" "unprognostic (3.17e-1)" "unprognostic (7.47e-2)" "unprognostic (1.37e-1)" TBC1D30 KIAA0984 ENSG00000111490 "TBC1 domain family member 30" Q9Y2I9 12 64759484-64881033 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 11.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 29.9;Inhibitory neurons: 41.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039772, HPA040043" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" "Plasma membrane" Cytosol "HPA039772: AB_10795409, HPA040043: AB_10795411" "unprognostic (1.85e-1)" "unprognostic (6.95e-2)" "unprognostic (2.66e-1)" "prognostic favorable (3.61e-5)" "unprognostic (9.35e-2)" "unprognostic (2.09e-1)" "unprognostic (2.65e-5)" "prognostic favorable (5.08e-4)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.44e-1)" "unprognostic (9.72e-2)" "unprognostic (7.32e-2)" "unprognostic (7.62e-3)" "unprognostic (8.72e-2)" "unprognostic (2.67e-3)" "unprognostic (7.80e-3)" TCF15 "bHLHa40, EC2, PARAXIS" ENSG00000125878 "Transcription factor 15" Q12870 20 604257-610309 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 27.0;skeletal muscle: 20.2;tongue: 14.5" "Cell type enriched" "Detected in some" 7 "Adipocytes: 193.1" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 4.5" "Adipose visceral - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050998, HPA060221" Approved Supported "Nuclear speckles" NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 47: Endothelial cells - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Nuclear speckles" "HPA050998: AB_2681302, HPA060221: AB_2684225" "unprognostic (2.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.58e-2)" "unprognostic (3.55e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.57e-2)" "unprognostic (2.33e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.52e-1)" "unprognostic (9.43e-2)" "unprognostic (1.27e-3)" "unprognostic (7.21e-2)" "unprognostic (8.56e-2)" "unprognostic (5.11e-1)" "unprognostic (6.99e-2)" TCF4 "bHLHb19, E2-2, ITF2, SEF2-1B" ENSG00000196628 "Transcription factor 4" P15884 18 55222185-55664787 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Disease variant, Epilepsy, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 788.5;dendritic cells: 1062.4;Inhibitory neurons: 1126.8;Oligodendrocyte precursor cells: 675.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "memory B-cell: 174.1;naive B-cell: 147.6;plasmacytoid DC: 560.8" "Group enriched" "Detected in many" 33 "B-cells: 174.1;dendritic cells: 560.8" "Cancer enhanced" "Detected in all" "Neuroblastoma: 66.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020722, HPA025958" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 62: Connective tissue - ECM organization" "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 124 "Nucleoplasm, Cytosol" "CAB020722: , HPA025958: AB_1857849" "unprognostic (2.11e-1)" "unprognostic (9.10e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-2)" "unprognostic (8.64e-2)" "unprognostic (1.79e-2)" "unprognostic (3.29e-2)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (1.99e-3)" "unprognostic (2.68e-2)" "unprognostic (2.76e-3)" "prognostic unfavorable (9.95e-4)" TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 44.7" "Group enriched" "Detected in some" 6 "Adipocytes: 67.0;Endothelial cells: 74.2;Lymphatic endothelial cells: 34.9;Microglial cells: 36.7;Oligodendrocyte precursor cells: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Rhabdoid: 17.5;testis cancer: 16.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" Receptor NA NA 7750000 13000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" TESC "CHP3, FLJ20607, TSC" ENSG00000088992 Tescalcin Q96BS2 12 117038923-117099479 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 320.1" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 259.2;Gastric mucus-secreting cells: 303.6;Late spermatids: 316.9;monocytes: 237.6;Oocytes: 233.8;Serous glandular cells: 553.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 262.4" "Lineage enriched" "Detected in all" 5 "monocytes: 262.4" "Cancer enhanced" "Detected in many" "Bile duct cancer: 88.8;Gastric cancer: 89.6;Leukemia: 85.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053200 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" 3 Nucleoplasm Cytosol "HPA053200: AB_2682079" "unprognostic (4.53e-3)" "unprognostic (5.98e-2)" "unprognostic (6.50e-2)" "unprognostic (2.23e-3)" "unprognostic (6.31e-2)" "unprognostic (2.05e-3)" "unprognostic (4.98e-3)" "unprognostic (3.35e-1)" "unprognostic (4.35e-1)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.69e-2)" "unprognostic (8.65e-2)" "unprognostic (2.57e-1)" "unprognostic (1.56e-2)" "unprognostic (5.67e-3)" THSD1 TMTSP ENSG00000136114 "Thrombospondin type 1 domain containing 1" Q9NS62 13 52377167-52416373 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 18.2;Astrocytes: 24.2;Basal respiratory cells: 13.3;Endothelial cells: 23.5;Lymphatic endothelial cells: 20.6;Microglial cells: 17.0;Spermatocytes: 14.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012611, CAB020796, HPA071106" Supported Supported Cytosol "Intracellular and membrane" "No annotated function" No No 1400000 "Cluster 34: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" Cytosol "CAB020796: , HPA012611: AB_1857990, HPA071106: " "unprognostic (1.21e-1)" "unprognostic (7.54e-3)" "unprognostic (3.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.31e-1)" "unprognostic (1.54e-2)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-1)" "unprognostic (6.10e-3)" "unprognostic (1.55e-1)" "unprognostic (3.05e-3)" "unprognostic (8.44e-2)" "unprognostic (1.31e-1)" "unprognostic (3.35e-2)" "unprognostic (4.90e-2)" THSD7A KIAA0960 ENSG00000005108 "Thrombospondin type 1 domain containing 7A" Q9UPZ6 7 11370365-11832198 "Disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 7.3" "Cell type enhanced" "Detected in many" "Astrocytes: 142.7;Bipolar cells: 160.4;Horizontal cells: 97.6;Inhibitory neurons: 470.6;Microglial cells: 101.1;Oligodendrocyte precursor cells: 246.2" "Cancer enhanced" "Detected in many" "renal cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 53 "basophil: 5.3" "Lineage enriched" "Detected in single" 53 "granulocytes: 5.3" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 11.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000923 Supported "Secreted to blood" "Developmental protein" NA NA 6100000 "Cluster 46: Basophils - Proteolysis" "Cluster 51: Thyroid gland - Unknown function" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 12 "HPA000923: AB_1080271" "unprognostic (3.01e-1)" "unprognostic (7.90e-2)" "unprognostic (3.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.88e-1)" "unprognostic (3.33e-2)" "unprognostic (1.44e-1)" "unprognostic (9.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (2.07e-1)" "unprognostic (8.75e-2)" "prognostic favorable (2.24e-6)" "unprognostic (2.13e-3)" "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (3.33e-2)" TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Adipocytes: 124.3;Endothelial cells: 103.9;Lymphatic endothelial cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.2;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.2;NK-cells: 2.5" "Group enriched" "Detected in some" 5 "Leukemia: 14.3;ovarian cancer: 18.9;Sarcoma: 23.2;thyroid cancer: 28.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA 87000000 "Cluster 15: NK-cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 7 "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" TINAGL1 "ARG1, LCN7, LIECG3, P3ECSL, TINAGRP" ENSG00000142910 "Tubulointerstitial nephritis antigen like 1" Q9GZM7 1 31576485-31587686 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 315.0;Cytotrophoblasts: 1165.2;Ductal cells: 358.8;Smooth muscle cells: 371.6;Syncytiotrophoblasts: 1713.9" "Cancer enhanced" "Detected in all" "urothelial cancer: 87.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 328.7" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Smooth muscle cells, Skin - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048695 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 370000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" 4 "HPA048695: AB_2680497" "unprognostic (1.27e-1)" "unprognostic (2.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-3)" "unprognostic (8.29e-3)" "unprognostic (6.02e-3)" "unprognostic (4.18e-1)" "unprognostic (6.96e-2)" "unprognostic (7.02e-3)" "unprognostic (1.22e-1)" "prognostic favorable (3.65e-6)" "unprognostic (7.42e-2)" "unprognostic (6.64e-2)" "prognostic favorable (9.64e-4)" "unprognostic (3.43e-2)" TM4SF18 L6D ENSG00000163762 "Transmembrane 4 L six family member 18" Q96CE8 3 149318498-149334414 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.0" "Group enriched" "Detected in many" 4 "Adipocytes: 205.7;Endothelial cells: 149.8;Lymphatic endothelial cells: 167.6" "Cancer enhanced" "Detected in all" "renal cancer: 17.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 89.0" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in many" "HPA058640, HPA069378" Approved Approved "Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 30 "Plasma membrane" "HPA058640: , HPA069378: AB_2686133" "unprognostic (2.25e-1)" "unprognostic (3.68e-1)" "unprognostic (4.76e-2)" "unprognostic (1.08e-1)" "unprognostic (9.11e-3)" "unprognostic (1.05e-2)" "prognostic favorable (8.63e-4)" "unprognostic (2.84e-1)" "unprognostic (6.13e-3)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (1.75e-1)" "unprognostic (5.71e-2)" "unprognostic (3.56e-3)" "unprognostic (1.65e-1)" "unprognostic (3.01e-1)" "unprognostic (1.97e-1)" TMC7 FLJ21240 ENSG00000170537 "Transmembrane channel like 7" Q7Z402 16 18983934-19063942 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;testis: 9.3;urinary bladder: 7.8" "Cell type enhanced" "Detected in many" "Early spermatids: 219.4;Late spermatids: 45.8;Oligodendrocytes: 89.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029465 Uncertain Approved Vesicles NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 18: Early spermatids - Unknown function" Vesicles "HPA029465: AB_10600914" "unprognostic (1.80e-4)" "unprognostic (6.13e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.25e-1)" "unprognostic (1.19e-3)" "unprognostic (7.60e-5)" "prognostic unfavorable (3.20e-4)" "unprognostic (7.60e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.64e-4)" "unprognostic (3.39e-1)" "unprognostic (1.00e-1)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (5.66e-2)" "prognostic favorable (9.20e-4)" TMEM47 "BCMP1, DKFZp564E153, DKFZP761J17121, TM4SF10, VAB-9" ENSG00000147027 "Transmembrane protein 47" Q9BQJ4 X 34627075-34657285 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 101.8;Astrocytes: 81.1;Leydig cells: 73.6;Melanocytes: 118.5;Muller glia cells: 130.2;Peritubular cells: 91.6;Smooth muscle cells: 84.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046658 Approved Approved "Nuclear membrane" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 5 "Nuclear membrane" "HPA046658: AB_2679742" "unprognostic (1.50e-1)" "unprognostic (1.44e-1)" "unprognostic (5.97e-2)" "unprognostic (1.35e-1)" "unprognostic (1.52e-1)" "unprognostic (3.82e-2)" "unprognostic (6.74e-3)" "unprognostic (7.29e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.67e-2)" "unprognostic (4.23e-2)" "unprognostic (1.36e-1)" "prognostic favorable (4.05e-6)" "unprognostic (2.69e-2)" "unprognostic (7.19e-2)" "unprognostic (2.76e-1)" "unprognostic (9.94e-2)" TNFRSF10A "Apo2, CD261, DR4, TRAILR-1, TRAILR1" ENSG00000104689 "TNF receptor superfamily member 10a" O00220 8 23190452-23225102 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" HPA054475 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "HPA054475: AB_2682500" "unprognostic (3.66e-1)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (4.89e-2)" "unprognostic (9.44e-2)" "unprognostic (8.39e-2)" "unprognostic (5.32e-2)" "unprognostic (2.18e-2)" "unprognostic (2.72e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (1.00e-4)" "unprognostic (1.49e-1)" "unprognostic (1.99e-3)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-1)" "unprognostic (2.87e-1)" TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716910-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 107.3;Leydig cells: 79.3;Muller glia cells: 93.7;Peritubular cells: 73.7" "Cancer enhanced" "Detected in all" "melanoma: 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.7" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.7" "Cancer enhanced" "Detected in all" "Neuroblastoma: 129.2;skin cancer: 129.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Liver - Vascular Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 69: Skin cancer - ECM organization" "Cluster 10: Muller glia cells - Visual perception" 2 Nucleoplasm Cytosol "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" TSPAN12 "NET-2, TM4SF12" ENSG00000106025 "Tetraspanin 12" O95859 7 120787320-120858402 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 88.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 83.5;Collecting duct cells: 93.4;Distal tubular cells: 141.4;Glandular and luminal cells: 90.9;Proximal tubular cells: 90.7" "Cancer enhanced" "Detected in all" "renal cancer: 44.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Hepatocytes, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051570, HPA058244" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 3: Basal prostatic cells - Lipid metabolism" 21 Microtubules Vesicles "HPA051570: , HPA058244: AB_2683652" "unprognostic (2.40e-2)" "unprognostic (7.60e-2)" "unprognostic (3.66e-3)" "unprognostic (1.82e-2)" "unprognostic (3.97e-1)" "unprognostic (7.34e-3)" "unprognostic (1.60e-1)" "unprognostic (8.12e-2)" "unprognostic (1.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (9.53e-2)" "unprognostic (7.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.43e-1)" TSPAN13 "NET-6, TM4SF13" ENSG00000106537 "Tetraspanin 13" O95857 7 16753755-16784536 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 295.2;Alveolar cells type 1: 429.5;Cytotrophoblasts: 291.2;dendritic cells: 370.5;Intestinal goblet cells: 367.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 99.9;plasmacytoid DC: 232.1" "Group enriched" "Detected in many" 42 "B-cells: 99.9;dendritic cells: 232.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007426 Uncertain Uncertain Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm "HPA007426: AB_10603137" "unprognostic (3.22e-1)" "unprognostic (1.45e-2)" "unprognostic (1.48e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (3.56e-5)" "unprognostic (2.63e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (5.69e-2)" "unprognostic (6.63e-2)" "prognostic favorable (2.20e-4)" "unprognostic (1.50e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-1)" TSPAN7 "A15, CD231, DXS1692E, MRX58, MXS1, TALLA-1, TM4SF2" ENSG00000156298 "Tetraspanin 7" P41732 X 38561542-38688920 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 480.8" "Cell type enhanced" "Detected in many" "Astrocytes: 260.7;Cone photoreceptor cells: 156.3;Endothelial cells: 163.0;Excitatory neurons: 208.4;Inhibitory neurons: 238.7;Oligodendrocyte precursor cells: 331.6" "Cancer enhanced" "Detected in all" "glioma: 71.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 60.4;Neuroblastoma: 61.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Sinusoid Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003140, CAB062566, CAB068245" Enhanced NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "CAB062566: AB_2665608, CAB068245: AB_2665609, HPA003140: AB_1078454" "unprognostic (1.12e-2)" "unprognostic (1.42e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.40e-4)" "unprognostic (5.06e-2)" "unprognostic (3.90e-3)" "unprognostic (3.88e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.01e-2)" "prognostic favorable (1.70e-4)" "unprognostic (1.54e-1)" "prognostic favorable (5.48e-7)" "unprognostic (5.65e-3)" "unprognostic (9.53e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-3)" TSPAN9 NET-5 ENSG00000011105 "Tetraspanin 9" O75954 12 3077355-3286564 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 151.0;heart muscle: 124.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.2;Extravillous trophoblasts: 116.0;Syncytiotrophoblasts: 74.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 198.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 80.5" HPA014002 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 50: Connective tissue cells - ECM organization" "Nucleoplasm, Golgi apparatus" Cytosol "HPA014002: AB_2304038" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.40e-2)" "unprognostic (1.41e-2)" "unprognostic (1.08e-2)" "unprognostic (3.53e-2)" "unprognostic (3.11e-2)" "unprognostic (7.30e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" "unprognostic (1.26e-2)" "unprognostic (1.89e-1)" "unprognostic (6.70e-2)" "unprognostic (1.57e-1)" "unprognostic (2.68e-2)" "unprognostic (1.04e-2)" TTLL10 "FLJ36119, TTLL5" ENSG00000162571 "Tubulin tyrosine ligase like 10" Q6ZVT0 1 1173880-1197936 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "fallopian tube: 10.4;testis: 40.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 765.3" "Cancer enhanced" "Detected in some" "cervical cancer: 1.5;endometrial cancer: 1.5" "Region enhanced" "Detected in many" "choroid plexus: 28.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA042712 Uncertain NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Late spermatids - Unknown function" 10 "HPA042712: AB_10797019" "unprognostic (1.74e-1)" "unprognostic (7.95e-2)" "unprognostic (2.66e-3)" "prognostic favorable (1.61e-5)" "unprognostic (5.33e-2)" "unprognostic (2.68e-3)" "unprognostic (4.93e-3)" "unprognostic (2.14e-3)" "unprognostic (4.50e-1)" "unprognostic (3.69e-2)" "unprognostic (1.28e-2)" "unprognostic (6.63e-2)" "unprognostic (6.00e-4)" "unprognostic (8.35e-2)" "unprognostic (2.65e-1)" "unprognostic (1.12e-1)" "unprognostic (4.39e-2)" USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 37.3;Endothelial cells: 25.8;Lymphatic endothelial cells: 30.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052471 Uncertain NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 162 "HPA052471: AB_2681843" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-3)" "unprognostic (1.44e-3)" "unprognostic (3.94e-2)" "unprognostic (4.42e-3)" "unprognostic (2.52e-1)" "unprognostic (4.46e-3)" "unprognostic (5.12e-1)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.88e-1)" UTRN "DMDL, DRP, DRP1" ENSG00000152818 Utrophin P46939 6 144285335-144853034 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 542.8;Late spermatids: 385.0;Lymphatic endothelial cells: 440.1;Microglial cells: 406.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 157.0" "Lineage enriched" "Detected in all" 4 "monocytes: 157.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016348, HPA018894" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 4200 "Cluster 40: Monocytes - Innate immune response" "Cluster 16: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" 2 "Nucleoplasm, Plasma membrane" "CAB016348: AB_628424, HPA018894: AB_10600839" "unprognostic (3.47e-2)" "unprognostic (2.82e-1)" "unprognostic (2.32e-1)" "unprognostic (6.87e-3)" "unprognostic (1.75e-1)" "unprognostic (3.30e-2)" "unprognostic (3.99e-3)" "unprognostic (2.44e-1)" "unprognostic (9.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.10e-2)" "prognostic favorable (7.61e-5)" "unprognostic (6.32e-2)" "unprognostic (2.20e-1)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 496.6;Endothelial cells: 348.7;Melanocytes: 324.7;monocytes: 306.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 58 "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" VASP ENSG00000125753 "Vasodilator stimulated phosphoprotein" P50552 19 45506579-45526989 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 506.5;monocytes: 471.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 88.1;monocytes: 50.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004612, HPA005724" Enhanced Supported "Plasma membrane,Cell Junctions,Focal adhesion sites" NA NA 32000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 4: Non-specific - Transcription" "Cluster 58: Macrophages - Innate immune response" 15 "Plasma membrane, Cell Junctions, Focal adhesion sites" "CAB004612: AB_2213431, HPA005724: AB_1858721" "unprognostic (3.07e-2)" "unprognostic (1.07e-2)" "unprognostic (4.70e-2)" "unprognostic (7.85e-3)" "unprognostic (8.31e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.66e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-2)" "unprognostic (3.64e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (5.91e-7)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.08e-2)" VWF F8VWF ENSG00000110799 "Von Willebrand factor" P04275 12 5948877-6124770 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets, von Willebrand disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 917.4;Endothelial cells: 827.6" "Cancer enhanced" "Detected in all" "renal cancer: 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001694, HPA001815, HPA002082, CAB072874, CAB072875" Supported "Secreted to blood" "Blood coagulation" NA NA 28300000000 5600000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "CAB001694: , CAB072874: AB_2665726, CAB072875: AB_2665727, HPA001815: AB_611880, HPA002082: AB_1080575" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (2.91e-3)" "unprognostic (7.09e-2)" "unprognostic (4.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.92e-2)" "unprognostic (4.69e-1)" "unprognostic (1.12e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (1.55e-1)" "unprognostic (3.12e-1)" "unprognostic (2.73e-3)" WWC3 "BM042, KIAA1280" ENSG00000047644 "WWC family member 3" Q9ULE0 X 10015254-10144474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 71.0;Alveolar cells type 2: 136.4;Basal prostatic cells: 127.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" HPA039814 Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 53: Non-specific - Glycosylation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 3: Basal prostatic cells - Lipid metabolism" Cytosol "Actin filaments" "HPA039814: AB_10674987" "unprognostic (2.53e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (9.84e-3)" "unprognostic (1.05e-1)" "unprognostic (1.80e-1)" "unprognostic (3.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.83e-2)" "unprognostic (3.58e-2)" "unprognostic (4.91e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (9.90e-2)" "unprognostic (2.09e-1)" "unprognostic (5.03e-2)" "unprognostic (4.50e-2)" YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.1" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 44: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 44 "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 17.2;Cone photoreceptor cells: 13.6;Endothelial cells: 21.0;Langerhans cells: 9.1;Microglial cells: 51.9;Skeletal myocytes: 7.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.3" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.3" "Not detected" "Not detected" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526" Uncertain Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 22 Nucleoplasm "HPA023128: AB_1859223, HPA023526: AB_1859224" "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)"