Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" AACS "ACSF1, FLJ12389, SUR-5" ENSG00000081760 "Acetoacetyl-CoA synthetase" Q86V21 12 125065434-125143333 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 59.5;Excitatory neurons: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058815 Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 17: Breast glandular cells - Lactation" 1 Vesicles "HPA058815: AB_2683826" "unprognostic (1.28e-1)" "unprognostic (9.78e-2)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-3)" "unprognostic (6.60e-6)" "unprognostic (3.03e-2)" "unprognostic (3.32e-2)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" "unprognostic (3.04e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (7.71e-2)" "unprognostic (6.80e-2)" AADAC "CES5A1, DAC" ENSG00000114771 "Arylacetamide deacetylase" P22760 3 151814073-151828488 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 217.8;intestine: 235.1;liver: 917.3" "Group enriched" "Detected in many" 7 "Hepatocytes: 594.9;Proximal enterocytes: 435.0" "Cancer enriched" "Detected in many" 22 "liver cancer: 153.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 68.3;liver cancer: 39.2" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA002911 Approved NA NA "Cluster 83: Liver - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "HPA002911: AB_1078074" "unprognostic (1.26e-1)" "unprognostic (1.82e-2)" "unprognostic (8.11e-2)" "unprognostic (4.41e-2)" "unprognostic (9.23e-2)" "unprognostic (7.82e-2)" "unprognostic (2.15e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.58e-6)" "prognostic unfavorable (5.02e-4)" "prognostic unfavorable (2.19e-4)" "unprognostic (1.22e-1)" "unprognostic (1.27e-1)" ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.3;liver: 49.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 221.3;Distal enterocytes: 227.9;Exocrine glandular cells: 119.5;Gastric mucus-secreting cells: 229.3;Hepatocytes: 150.5;Late spermatids: 128.5;Paneth cells: 182.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" ABCC5 "EST277145, MOAT-C, MRP5, SMRP" ENSG00000114770 "ATP binding cassette subfamily C member 5" O15440 3 183919934-184017939 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 125.7;Excitatory neurons: 97.9;Inhibitory neurons: 117.9;Rod photoreceptor cells: 121.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 323.0" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044067, HPA052295" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA044067: AB_2678797, HPA052295: AB_2681789" "unprognostic (9.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.83e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.78e-8)" "unprognostic (4.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.02e-1)" "unprognostic (5.91e-3)" "prognostic unfavorable (3.40e-4)" "unprognostic (1.10e-1)" "unprognostic (9.05e-3)" "unprognostic (1.64e-1)" "unprognostic (3.33e-2)" "unprognostic (1.24e-2)" ABHD17C FAM108C1 ENSG00000136379 "Abhydrolase domain containing 17C, depalmitoylase" Q6PCB6 15 80679684-80755621 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 63.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 148.3;Intestinal goblet cells: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048890 Uncertain NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 11 "HPA048890: AB_2680546" "unprognostic (3.60e-1)" "unprognostic (5.07e-2)" "unprognostic (1.58e-1)" "unprognostic (2.19e-2)" "unprognostic (7.51e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" "unprognostic (2.32e-1)" "unprognostic (1.40e-1)" "unprognostic (2.59e-2)" "unprognostic (5.08e-3)" "unprognostic (2.87e-1)" "unprognostic (1.23e-3)" "unprognostic (5.75e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" "unprognostic (1.89e-3)" ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 113.2" "Cell type enhanced" "Detected in all" "Distal enterocytes: 137.5;Hepatocytes: 108.1;Intestinal goblet cells: 122.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Group enriched" "Detected in many" 5 "dendritic cells: 22.6;granulocytes: 34.5;monocytes: 21.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004141 Approved NA NA 16000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 35: Non-specific - Mitochondria" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 62: Hepatocytes - Metabolism" "HPA004141: AB_1078094" "unprognostic (1.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.25e-2)" "unprognostic (1.84e-2)" "unprognostic (1.86e-1)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (3.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.42e-2)" "prognostic favorable (2.04e-4)" "unprognostic (2.72e-1)" "unprognostic (2.32e-1)" "unprognostic (3.08e-1)" "unprognostic (2.54e-1)" ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.0;kidney: 19.7;urinary bladder: 41.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 62.2;Ciliated cells: 66.8;Club cells: 124.5;Collecting duct cells: 101.1;Glandular and luminal cells: 55.9;Ionocytes: 157.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 62.2" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" Receptor NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 581.0;liver: 1997.6;stomach 1: 555.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 230.3;Enteroendocrine cells: 216.1;Exocrine glandular cells: 344.5;Gastric mucus-secreting cells: 669.1;Hepatocytes: 514.4;Undifferentiated cells: 339.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 53.7" "Liver - Hepatocytes, Stomach - Gastric mucous cells" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" NA NA 31000000 "Cluster 83: Liver - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.55e-4)" "prognostic favorable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435510 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 194.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 113.2;Basal respiratory cells: 76.9;Basal squamous epithelial cells: 58.3;Club cells: 53.1;Squamous epithelial cells: 235.2;Suprabasal keratinocytes: 202.2" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Esophageal cancer: 32.8;Gallbladder cancer: 101.9" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" AGR2 "AG2, HAG-2, PDIA17, XAG-2" ENSG00000106541 "Anterior gradient 2, protein disulphide isomerase family member" O95994 7 16791811-16833433 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 615.9;intestine: 1184.3;stomach 1: 1365.8" "Cell type enhanced" "Detected in many" "Club cells: 1768.3;Distal enterocytes: 1389.8;Enteroendocrine cells: 1388.6;Gastric mucus-secreting cells: 2597.0;Intestinal goblet cells: 7831.2;Undifferentiated cells: 1511.5" "Cancer enhanced" "Detected in many" "stomach cancer: 475.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 605.6;Gastric cancer: 837.5" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007912 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 38000 "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 62 "Endoplasmic reticulum" "HPA007912: AB_1844879" "unprognostic (6.19e-2)" "unprognostic (1.91e-1)" "unprognostic (9.05e-2)" "unprognostic (2.59e-2)" "unprognostic (2.23e-1)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.49e-2)" "unprognostic (1.84e-1)" "unprognostic (1.08e-2)" "unprognostic (3.24e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (8.79e-5)" "unprognostic (6.98e-2)" "unprognostic (2.38e-1)" "unprognostic (2.38e-1)" "unprognostic (3.22e-3)" AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549110-134579875 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "breast: 162.7" "Cell type enriched" "Detected in some" 4 "Syncytiotrophoblasts: 17.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Stomach - Gastric mucous cells, Testis - Spermatogonia" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 73: Breast - Lactation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Cytosol "Plasma membrane" "HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (9.74e-3)" "unprognostic (2.74e-2)" "unprognostic (2.08e-1)" "prognostic favorable (8.36e-4)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.04e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-1)" "unprognostic (2.14e-3)" "unprognostic (1.24e-1)" "unprognostic (1.22e-7)" "unprognostic (6.88e-2)" "unprognostic (4.29e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (1.90e-5)" AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 428.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 375.3;Cholangiocytes: 311.0;Exocrine glandular cells: 549.8;Hepatocytes: 451.0;Proximal enterocytes: 608.0;Proximal tubular cells: 497.6" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.9;gdT-cell: 102.8" "Group enriched" "Detected in many" 4 "granulocytes: 244.9;T-cells: 102.8" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1748.7" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 41: Basophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 482.2;salivary gland: 124.2;stomach 1: 218.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 545.9;Basal respiratory cells: 371.4;Basal squamous epithelial cells: 246.4;Ciliated cells: 213.5;Gastric mucus-secreting cells: 419.8;Ionocytes: 191.1;Serous glandular cells: 210.5;Squamous epithelial cells: 366.6;Suprabasal keratinocytes: 928.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Region enriched" "Detected in many" 8 "choroid plexus: 35.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 3329.2" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" AMN amnionless ENSG00000166126 "Amnion associated transmembrane protein" Q9BXJ7 14 102922663-102933596 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protein transport, Transport" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 81.3;kidney: 38.7;liver: 36.9" "Group enriched" "Detected in many" 4 "Distal enterocytes: 671.4;Proximal enterocytes: 1890.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.1;Gastric cancer: 6.2;liver cancer: 6.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA000817 Approved "Secreted in other tissues" Transport NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA000817: AB_1078146" "unprognostic (2.02e-2)" "unprognostic (1.67e-1)" "unprognostic (3.94e-3)" "unprognostic (7.39e-3)" "unprognostic (9.32e-2)" "unprognostic (1.88e-3)" "unprognostic (8.68e-2)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (2.97e-2)" "unprognostic (7.57e-2)" "unprognostic (2.43e-2)" "prognostic favorable (9.62e-5)" "unprognostic (8.02e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 52 "liver: 2920.4" "Cell type enriched" "Detected in many" 25 "Hepatocytes: 5169.3" "Cancer enriched" "Detected in all" 17 "liver cancer: 279.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.6;myeloid DC: 14.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" "Developmental protein" Yes No 308000000 410000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 31: Liver - Plasma proteins" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 5 "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.77e-2)" "prognostic favorable (6.85e-4)" "unprognostic (5.71e-3)" "unprognostic (6.99e-2)" "prognostic favorable (7.83e-5)" "unprognostic (1.16e-1)" "unprognostic (3.20e-3)" "unprognostic (9.19e-3)" "unprognostic (1.31e-1)" "unprognostic (3.69e-1)" "unprognostic (6.65e-2)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (2.00e-1)" "unprognostic (3.09e-1)" ANKDD1B ENSG00000189045 "Ankyrin repeat and death domain containing 1B" A6NHY2 5 75611182-75681773 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.2;intestine: 3.3;kidney: 3.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 23.7;Gastric mucus-secreting cells: 7.1;Intestinal goblet cells: 7.5;Proximal tubular cells: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA059722 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 42: Ciliated cells - Cilium assembly" "HPA059722: AB_2684112" "unprognostic (5.11e-3)" "unprognostic (2.46e-2)" "unprognostic (3.06e-2)" "unprognostic (6.16e-2)" "unprognostic (3.26e-1)" "unprognostic (2.42e-1)" "unprognostic (2.39e-1)" "unprognostic (7.84e-3)" "unprognostic (2.59e-2)" "unprognostic (2.41e-1)" "unprognostic (7.36e-2)" "unprognostic (1.62e-1)" "prognostic favorable (2.30e-7)" "unprognostic (1.87e-2)" "unprognostic (1.02e-1)" "unprognostic (2.28e-1)" "unprognostic (1.27e-2)" ANKRD40CL "C17orf73, FLJ20694, LINC00483" ENSG00000167117 "ANKRD40 C-terminal like" Q53H64 17 50761029-50767557 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "intestine: 58.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 176.4;Paneth cells: 116.4;Proximal enterocytes: 330.8" "Group enriched" "Detected in some" 12 "colorectal cancer: 3.3;pancreatic cancer: 0.8;stomach cancer: 2.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.9;Gastric cancer: 9.1" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "unprognostic (2.98e-1)" "unprognostic (1.96e-2)" "unprognostic (2.02e-3)" "unprognostic (2.76e-1)" "unprognostic (4.52e-1)" "unprognostic (1.95e-1)" "unprognostic (2.09e-2)" "unprognostic (8.37e-2)" "unprognostic (1.57e-2)" "unprognostic (6.81e-2)" "unprognostic (1.67e-1)" "unprognostic (1.05e-3)" ANKS4B "FLJ38819, HARP" ENSG00000175311 "Ankyrin repeat and sterile alpha motif domain containing 4B" Q8N8V4 16 21233699-21253850 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 11.9;kidney: 5.7;liver: 13.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 54.5;Enteroendocrine cells: 38.1;Hepatocytes: 25.5;Intestinal goblet cells: 44.1;Paneth cells: 34.3;Proximal enterocytes: 104.4;Proximal tubular cells: 27.0;Undifferentiated cells: 21.6" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.2;liver cancer: 5.1;pancreatic cancer: 3.2;renal cancer: 3.3;stomach cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6;Gastric cancer: 3.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA043523, HPA061125" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 1 "Nucleoplasm, Cytosol" "HPA043523: AB_10966687, HPA061125: " "unprognostic (1.35e-1)" "unprognostic (4.96e-2)" "unprognostic (2.73e-2)" "unprognostic (3.32e-2)" "unprognostic (8.42e-3)" "unprognostic (8.61e-2)" "unprognostic (2.36e-1)" "unprognostic (9.48e-2)" "unprognostic (2.04e-1)" "unprognostic (4.08e-1)" "unprognostic (1.08e-1)" "unprognostic (9.75e-4)" "unprognostic (5.15e-3)" "unprognostic (1.88e-1)" "unprognostic (4.77e-2)" "unprognostic (4.34e-3)" ANO7 "IPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G" ENSG00000146205 "Anoctamin 7" Q6IWH7 2 241188509-241225976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.9;prostate: 68.5;stomach 1: 27.7" "Group enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 66.6;Intestinal goblet cells: 67.3;Prostatic glandular cells: 68.0" "Cancer enriched" "Detected in many" 19 "prostate cancer: 32.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 6.6" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" HPA078464 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA078464: " "unprognostic (1.93e-2)" "unprognostic (3.45e-3)" "unprognostic (1.09e-3)" "unprognostic (5.13e-2)" "unprognostic (1.35e-2)" "unprognostic (8.76e-2)" "unprognostic (3.09e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-2)" "unprognostic (8.45e-2)" "unprognostic (2.90e-2)" "unprognostic (4.94e-2)" "unprognostic (4.82e-3)" "unprognostic (6.09e-2)" "unprognostic (1.61e-1)" "unprognostic (2.14e-1)" "unprognostic (2.53e-2)" ANXA10 ANX14 ENSG00000109511 "Annexin A10" Q9UJ72 4 168092537-168187736 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 473.8" "Cell type enriched" "Detected in some" 6 "Gastric mucus-secreting cells: 597.2" "Group enriched" "Detected in many" 5 "pancreatic cancer: 62.4;stomach cancer: 42.2;urothelial cancer: 19.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 72.6;Gastric cancer: 50.4;pancreatic cancer: 55.5" "Liver - Hepatocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005469, HPA074650" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" 2 "Nucleoplasm, Nucleoli" Vesicles "HPA005469: AB_1844849, HPA074650: " "unprognostic (2.29e-2)" "unprognostic (8.71e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (4.69e-1)" "unprognostic (2.29e-2)" "prognostic favorable (3.64e-6)" "unprognostic (1.18e-3)" "unprognostic (2.88e-1)" "unprognostic (8.61e-4)" "unprognostic (3.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-3)" "unprognostic (8.41e-2)" "unprognostic (4.01e-1)" "unprognostic (2.04e-1)" "unprognostic (8.89e-3)" AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 165.2;Proximal enterocytes: 170.4;Proximal tubular cells: 352.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA054999, HPA077258" Supported Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 Vesicles Cytosol "HPA054999: AB_2682666, HPA077258: " "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" AP1S3 sigma1C ENSG00000152056 "Adaptor related protein complex 1 subunit sigma 3" Q96PC3 2 223667680-223838027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 47.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 43.0;Cone photoreceptor cells: 44.2;Cytotrophoblasts: 48.0;granulocytes: 44.4;Langerhans cells: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 4.6;dendritic cells: 3.8;granulocytes: 5.6" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066782 Approved Supported Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 Vesicles "HPA066782: AB_2685720" "unprognostic (9.45e-3)" "unprognostic (1.79e-1)" "unprognostic (7.52e-2)" "unprognostic (5.80e-2)" "unprognostic (4.37e-2)" "unprognostic (4.89e-1)" "unprognostic (1.65e-3)" "prognostic unfavorable (3.36e-5)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.56e-1)" "unprognostic (2.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.32e-2)" "unprognostic (4.61e-2)" ARHGEF16 "GEF16, NBR" ENSG00000130762 "Rho guanine nucleotide exchange factor 16" Q5VV41 1 3454665-3481113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.4;Extravillous trophoblasts: 65.7;Gastric mucus-secreting cells: 56.6;Intestinal goblet cells: 57.1;Paneth cells: 48.6;Proximal enterocytes: 64.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in many" "olfactory bulb: 4.7" "Low region specificity" "Detected in many" HPA010609 Approved NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" 8 "HPA010609: AB_1845004" "unprognostic (1.28e-1)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (4.31e-1)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (2.65e-1)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (5.39e-2)" "unprognostic (9.16e-2)" "prognostic favorable (1.24e-10)" "unprognostic (6.46e-2)" "unprognostic (2.86e-1)" "unprognostic (1.71e-2)" "unprognostic (3.29e-2)" ARHGEF5 "GEF5, P60, TIM, TIM1" ENSG00000050327 "Rho guanine nucleotide exchange factor 5" Q12774 7 144355288-144380632 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 45.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 60.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA020980, HPA029504, HPA044188, HPA045619, HPA045699" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" 18 "Plasma membrane, Cytosol" Nucleoplasm "HPA020980: AB_1845007, HPA029504: AB_10602231, HPA044188: AB_2678850, HPA045619: AB_2679393, HPA045699: AB_2679423" "unprognostic (1.45e-1)" "unprognostic (2.05e-1)" "unprognostic (1.87e-2)" "unprognostic (1.94e-1)" "unprognostic (9.45e-2)" "unprognostic (2.69e-2)" "unprognostic (9.95e-3)" "unprognostic (9.21e-2)" "unprognostic (1.05e-2)" "unprognostic (2.27e-1)" "unprognostic (3.67e-2)" "unprognostic (2.12e-1)" "prognostic favorable (3.28e-7)" "unprognostic (4.67e-2)" "unprognostic (4.86e-1)" "unprognostic (2.36e-1)" "unprognostic (7.76e-2)" ARL14 "ARF7, FLJ22595" ENSG00000179674 "ADP ribosylation factor like GTPase 14" Q8N4G2 3 160677160-160678448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 124.9;intestine: 49.7;stomach 1: 75.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 337.3;Enteroendocrine cells: 126.1;Gastric mucus-secreting cells: 361.4;Intestinal goblet cells: 140.0;Paneth cells: 194.2;Proximal enterocytes: 143.4" "Group enriched" "Detected in many" 5 "colorectal cancer: 6.6;pancreatic cancer: 26.0;stomach cancer: 14.3;urothelial cancer: 8.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 15 "memory B-cell: 1.8" "Lineage enriched" "Detected in single" 18 "B-cells: 1.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 19.7" "Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 2 "unprognostic (2.65e-1)" "unprognostic (7.26e-3)" "unprognostic (2.64e-2)" "unprognostic (3.70e-3)" "unprognostic (6.36e-2)" "unprognostic (2.47e-3)" "prognostic unfavorable (2.64e-5)" "unprognostic (2.30e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (6.71e-4)" "unprognostic (4.74e-2)" "unprognostic (4.91e-2)" "unprognostic (2.36e-1)" "unprognostic (1.35e-1)" "unprognostic (1.62e-1)" "unprognostic (1.70e-2)" ASCC2 "ASC1p100, DKFZp586O0223, FLJ21588" ENSG00000100325 "Activating signal cointegrator 1 complex subunit 2" Q9H1I8 22 29788609-29838304 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001439, HPA052879" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 66: Non-specific - Mitochondria" "Cluster 11: Late spermatids - Unknown function" 3 "Focal adhesion sites, Cytosol" Nucleoplasm "HPA001439: AB_1078229, HPA052879: AB_2732577" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (8.58e-2)" "unprognostic (3.83e-3)" "unprognostic (1.84e-1)" "unprognostic (2.45e-3)" "unprognostic (3.01e-3)" "unprognostic (1.16e-1)" "unprognostic (1.35e-1)" "unprognostic (5.39e-2)" "unprognostic (1.56e-2)" "unprognostic (1.24e-1)" "unprognostic (3.97e-3)" "unprognostic (5.19e-2)" "unprognostic (7.53e-2)" "unprognostic (3.81e-1)" "unprognostic (2.05e-3)" ASL ASAL ENSG00000126522 "Argininosuccinate lyase" P04424 7 66075800-66094697 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 386.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 335.9;Hepatocytes: 508.0;Proximal enterocytes: 267.7;Proximal tubular cells: 221.3" "Cancer enhanced" "Detected in all" "liver cancer: 52.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003696, HPA016646" Enhanced Approved Cytosol NA NA 12000000 "Cluster 25: Non-specific - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 2 Cytosol "CAB003696: AB_425316, HPA016646: AB_1845096" "unprognostic (2.95e-2)" "prognostic unfavorable (4.05e-6)" "unprognostic (4.83e-1)" "unprognostic (4.18e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (2.07e-1)" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (7.25e-2)" "unprognostic (4.95e-2)" "unprognostic (2.07e-2)" "unprognostic (3.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (8.40e-3)" ASPHD2 FLJ39838 ENSG00000128203 "Aspartate beta-hydroxylase domain containing 2" Q6ICH7 22 26429260-26445015 "Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.0;skin 1: 10.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.8;Early spermatids: 13.6;Excitatory neurons: 13.7;Extravillous trophoblasts: 14.7;Late spermatids: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.3" "Group enriched" "Detected in many" 4 "dendritic cells: 2.2;monocytes: 5.3" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000820 Uncertain NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 65: Cerebellum - Nervous system development" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 11: Late spermatids - Unknown function" "HPA000820: AB_1078231" "unprognostic (1.12e-1)" "unprognostic (1.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.71e-1)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-2)" "unprognostic (8.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.06e-5)" "unprognostic (6.55e-2)" "unprognostic (9.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.11e-2)" ATP2A3 SERCA3 ENSG00000074370 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3" Q93084 17 3923870-3964464 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 99.1;salivary gland: 180.1" "Cell type enhanced" "Detected in many" "B-cells: 77.7;dendritic cells: 71.0;Distal enterocytes: 113.0;Enteroendocrine cells: 73.8;Gastric mucus-secreting cells: 117.9;Intestinal goblet cells: 136.4;Plasma cells: 80.0;Serous glandular cells: 71.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 134.5;lymphoma: 100.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - T-cells, Liver - T-cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in all" 15 "cerebellum: 67.2" "Low region specificity" "Detected in all" "HPA007180, CAB010882" Approved NA NA 5400000 "Cluster 22: Eosinophils - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 75: Serous glandular cells - Salivary secretion" "CAB010882: AB_258368, HPA007180: AB_1845177" "unprognostic (4.14e-2)" "prognostic favorable (4.69e-5)" "unprognostic (1.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.02e-2)" "prognostic favorable (2.51e-4)" "unprognostic (8.83e-3)" "unprognostic (2.30e-1)" "unprognostic (8.29e-2)" "unprognostic (3.67e-3)" "unprognostic (3.95e-3)" "unprognostic (1.73e-1)" "unprognostic (1.45e-3)" "unprognostic (1.60e-1)" "unprognostic (3.25e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-3)" AXDND1 "C1orf125, FLJ32940" ENSG00000162779 "Axonemal dynein light chain domain containing 1" Q5T1B0 1 179365720-179554735 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 15.3" "Group enriched" "Detected in some" 6 "Early spermatids: 237.4;Late spermatids: 260.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071114 Enhanced NA NA "Cluster 20: Testis - Spermatogenesis" "Cluster 3: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Late spermatids - Unknown function" "HPA071114: AB_2686345" "unprognostic (1.67e-2)" "unprognostic (8.37e-2)" "unprognostic (2.81e-2)" "unprognostic (1.05e-1)" "unprognostic (3.34e-1)" "unprognostic (1.73e-1)" "unprognostic (3.78e-4)" "unprognostic (2.62e-1)" "unprognostic (1.75e-1)" "unprognostic (6.99e-3)" "unprognostic (2.09e-2)" "unprognostic (1.31e-1)" "unprognostic (5.17e-3)" "unprognostic (1.92e-1)" "unprognostic (5.48e-2)" "unprognostic (5.04e-2)" "unprognostic (2.25e-1)" B3GNT6 B3Gn-T6 ENSG00000198488 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6" Q6ZMB0 11 77034398-77041973 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 21.0;salivary gland: 6.2;stomach 1: 24.2" "Group enriched" "Detected in some" 9 "Gastric mucus-secreting cells: 25.4;Intestinal goblet cells: 57.3" "Group enriched" "Detected in some" 14 "colorectal cancer: 6.3;lung cancer: 3.9;pancreatic cancer: 5.1;prostate cancer: 5.0;stomach cancer: 4.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.3;lung cancer: 1.8" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039805 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA039805: AB_2676690" "unprognostic (1.71e-1)" "prognostic favorable (2.31e-4)" "unprognostic (4.79e-2)" "unprognostic (5.42e-2)" "unprognostic (7.64e-2)" "unprognostic (1.95e-1)" "unprognostic (2.72e-1)" "unprognostic (1.23e-2)" "unprognostic (7.77e-2)" "unprognostic (2.19e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-1)" BCAS1 "AIBC1, NABC1, PMES-2" ENSG00000064787 "Brain enriched myelin associated protein 1" O75363 20 53936777-54070594 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 1541.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 140.4;Gastric mucus-secreting cells: 185.7;Intestinal goblet cells: 456.6;Oligodendrocyte precursor cells: 505.6;Oligodendrocytes: 668.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.7" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "breast cancer: 48.9" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033558, HPA051816, HPA054745" Enhanced Approved Vesicles NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Vesicles "CAB033558: AB_2274632, HPA051816: AB_2681623, HPA054745: AB_2682590" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (6.20e-2)" "unprognostic (7.23e-2)" "unprognostic (1.05e-1)" "unprognostic (2.43e-2)" "unprognostic (5.54e-2)" "unprognostic (1.86e-1)" "unprognostic (3.80e-1)" "unprognostic (1.19e-1)" "unprognostic (5.25e-2)" "unprognostic (2.91e-2)" "unprognostic (4.70e-3)" "unprognostic (3.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.75e-1)" "unprognostic (7.77e-3)" BCL2L15 "Bfk, C1orf178, FLJ22588" ENSG00000188761 "BCL2 like 15" Q5TBC7 1 113876816-113887581 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 13.1;intestine: 42.0;stomach 1: 17.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 108.9;Exocrine glandular cells: 93.4;Gastric mucus-secreting cells: 35.4;Intestinal goblet cells: 39.8;Proximal enterocytes: 158.6;Undifferentiated cells: 41.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bile duct cancer: 13.6;colorectal cancer: 16.7;Gastric cancer: 6.7;pancreatic cancer: 4.8" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in some" 32 "cerebellum: 32.9" "Low region specificity" "Detected in all" "HPA029732, HPA029733" Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 6 "HPA029732: AB_10599615, HPA029733: AB_10600422" "unprognostic (5.96e-2)" "unprognostic (6.41e-3)" "unprognostic (5.82e-2)" "prognostic favorable (5.63e-4)" "unprognostic (2.16e-1)" "unprognostic (6.23e-3)" "unprognostic (4.97e-4)" "unprognostic (1.74e-1)" "unprognostic (2.95e-1)" "unprognostic (1.46e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-1)" "unprognostic (2.42e-7)" "unprognostic (5.20e-2)" "unprognostic (2.24e-2)" "unprognostic (9.04e-3)" "unprognostic (4.27e-2)" BICDL1 "BICDR-1, CCDC64, FLJ26450" ENSG00000135127 "BICD family like cargo adaptor 1" Q6ZP65 12 119989236-120094494 "Predicted intracellular proteins" "Neurogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 125.3;pituitary gland: 78.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 117.2;Excitatory neurons: 101.9;Inhibitory neurons: 108.7;Mesothelial cells: 111.0;Rod photoreceptor cells: 194.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Adipose visceral - Mesothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061116 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 52: Kidney - Transmembrane transport" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Nucleoplasm, Cytosol" Vesicles "HPA061116: AB_2684433" "unprognostic (2.17e-1)" "prognostic favorable (6.50e-4)" "unprognostic (1.68e-3)" "unprognostic (3.05e-2)" "unprognostic (6.81e-4)" "prognostic favorable (3.15e-4)" "prognostic unfavorable (6.84e-4)" "unprognostic (5.11e-2)" "unprognostic (3.18e-2)" "unprognostic (4.63e-2)" "unprognostic (3.31e-3)" "unprognostic (7.26e-2)" "prognostic favorable (3.93e-5)" "prognostic favorable (1.21e-5)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (2.15e-1)" BLNK "BASH, bca, BLNK-s, Ly57, SLP-65, SLP65" ENSG00000095585 "B cell linker" Q8WV28 10 96189171-96271587 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "B-cells: 98.0;dendritic cells: 118.3;Microglial cells: 150.3;Plasma cells: 80.2;Proximal enterocytes: 81.4;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 111.3;naive B-cell: 94.9;plasmacytoid DC: 159.3" "Group enriched" "Detected in many" 83 "B-cells: 111.3;dendritic cells: 159.3" "Cancer enhanced" "Detected in many" "Leukemia: 18.6;lymphoma: 53.4" "Colon - T-cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009333, CAB016291, HPA038309, HPA038310" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 3 "Plasma membrane" Vesicles "CAB009333: AB_2290422, CAB016291: AB_626752, HPA038309: AB_2675945, HPA038310: AB_2675946" "unprognostic (4.86e-2)" "unprognostic (6.05e-3)" "unprognostic (1.00e-2)" "unprognostic (2.73e-2)" "unprognostic (2.29e-1)" "unprognostic (1.63e-3)" "unprognostic (1.08e-2)" "unprognostic (5.19e-2)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" "unprognostic (8.94e-2)" "unprognostic (3.73e-1)" "unprognostic (1.84e-2)" "unprognostic (5.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.46e-3)" "prognostic favorable (2.67e-6)" BTNL8 "BTN9.2, FLJ21458" ENSG00000113303 "Butyrophilin like 8" Q6UX41 5 180899077-180950906 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "intestine: 115.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 73.9;Intestinal goblet cells: 36.0;Paneth cells: 38.9;Proximal enterocytes: 189.8" "Group enriched" "Detected in some" 12 "colorectal cancer: 2.6;liver cancer: 1.5;pancreatic cancer: 2.8;stomach cancer: 3.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 12 "neutrophil: 234.3" "Lineage enriched" "Detected in many" 221 "granulocytes: 234.3" "Group enriched" "Detected in some" 5 "colorectal cancer: 3.8;Esophageal cancer: 1.8;Gastric cancer: 3.5;pancreatic cancer: 2.0" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA039738 Enhanced NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "HPA039738: AB_2676656" "unprognostic (4.31e-1)" "unprognostic (6.85e-6)" "unprognostic (6.99e-2)" "unprognostic (1.48e-1)" "unprognostic (6.33e-2)" "unprognostic (1.91e-1)" "unprognostic (6.27e-3)" "unprognostic (6.07e-2)" "unprognostic (3.08e-3)" "unprognostic (3.28e-1)" "unprognostic (1.67e-1)" "unprognostic (9.02e-2)" "unprognostic (4.96e-3)" "unprognostic (2.93e-1)" "unprognostic (1.42e-1)" "unprognostic (4.43e-1)" "unprognostic (1.17e-2)" BZW2 "5MP1, HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 256.0;skeletal muscle: 354.7;tongue: 248.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 368.6;Extravillous trophoblasts: 1003.3;Syncytiotrophoblasts: 808.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 53: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Cytosol" "HPA022813: AB_1845511, HPA026709: AB_10600752" "unprognostic (2.27e-3)" "unprognostic (1.77e-3)" "unprognostic (5.91e-2)" "unprognostic (4.79e-3)" "unprognostic (2.80e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (7.86e-8)" "unprognostic (9.13e-3)" "unprognostic (8.49e-3)" "unprognostic (2.81e-2)" "unprognostic (1.83e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.00e-1)" "unprognostic (1.66e-1)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" C15orf48 "COXFA4L3, MIR147BHG, MISTRAV, MOCCI, NMES1" ENSG00000166920 "Chromosome 15 open reading frame 48" Q9C002 15 45430579-45448761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 893.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4361.0;Enteroendocrine cells: 1468.6;Exocrine glandular cells: 2025.4;Intestinal goblet cells: 1372.4;Langerhans cells: 2561.4;Paneth cells: 2158.2;Proximal enterocytes: 3050.5;Undifferentiated cells: 1467.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 6.3" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;intermediate monocyte: 1.6;myeloid DC: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 606.0" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA012943 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "HPA012943: AB_2668774" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (7.83e-2)" "unprognostic (1.17e-1)" "unprognostic (9.74e-3)" "unprognostic (1.48e-3)" "unprognostic (1.28e-3)" "unprognostic (1.59e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-3)" "unprognostic (5.95e-2)" "unprognostic (8.86e-2)" "unprognostic (2.37e-1)" "unprognostic (6.51e-2)" "unprognostic (1.39e-1)" "unprognostic (3.66e-1)" C19orf33 "H2RSP, IMUP, IMUP-1, IMUP-2" ENSG00000167644 "Chromosome 19 open reading frame 33" Q9GZP8 19 38304164-38305006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 500.9;skin 1: 320.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2497.3;Intestinal goblet cells: 784.7;Paneth cells: 1264.3;Proximal enterocytes: 1796.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 10 "myeloid DC: 22.3" "Lineage enriched" "Detected in many" 10 "dendritic cells: 22.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 1, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA054406, HPA059696" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 460000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "HPA054406: AB_2682478, HPA059696: AB_2684105" "unprognostic (9.31e-2)" "unprognostic (2.06e-1)" "unprognostic (4.34e-2)" "unprognostic (1.44e-2)" "unprognostic (3.92e-3)" "unprognostic (2.37e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (5.42e-4)" "unprognostic (2.09e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (6.92e-2)" "unprognostic (5.50e-2)" "unprognostic (4.82e-2)" "unprognostic (1.61e-1)" "unprognostic (3.63e-2)" "unprognostic (6.01e-2)" C1orf210 "MGC52423, TEMP" ENSG00000253313 "Chromosome 1 open reading frame 210" Q8IVY1 1 43281877-43285617 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 123.1;Enteroendocrine cells: 46.7;Paneth cells: 62.0;Proximal enterocytes: 134.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 2.2" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.2" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013788 Uncertain Uncertain "Nucleoli,Nucleoli rim" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 5: Enterocytes - Absorption" "Nucleoli, Nucleoli rim" "HPA013788: AB_1845637" "unprognostic (1.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.54e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (0.00e+0)" "unprognostic (7.57e-3)" "unprognostic (3.94e-1)" "unprognostic (1.00e-1)" "unprognostic (1.61e-2)" C4orf19 FLJ11017 ENSG00000154274 "Chromosome 4 open reading frame 19" Q8IY42 4 37453925-37623495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 34.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 83.9;Distal enterocytes: 109.7;Enteroendocrine cells: 76.0;Exocrine glandular cells: 114.3;Proximal enterocytes: 105.0;Syncytiotrophoblasts: 97.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 8.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043458, HPA052894" Enhanced Approved "Nucleoplasm,Cell Junctions" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 4 Nucleoplasm "Cell Junctions" "HPA043458: AB_10960696, HPA052894: AB_2681982" "unprognostic (8.83e-2)" "unprognostic (7.86e-2)" "unprognostic (3.00e-3)" "unprognostic (2.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.59e-3)" "unprognostic (5.55e-2)" "unprognostic (2.29e-1)" "unprognostic (6.66e-2)" "unprognostic (9.96e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.49e-11)" "unprognostic (1.33e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-3)" "unprognostic (8.19e-3)" CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 971.6;intestine: 664.8;stomach 1: 1080.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3008.5;Erythroid cells: 1660.0;Gastric mucus-secreting cells: 1234.5;Muller glia cells: 1243.1;Paneth cells: 636.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 825.1" "Immune cell enhanced" "Detected in many" "basophil: 51.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" CAPN9 "GC36, nCL-4" ENSG00000135773 "Calpain 9" O14815 1 230747384-230802003 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 21.5;stomach 1: 58.8" "Group enriched" "Detected in some" 6 "Gastric mucus-secreting cells: 89.0;Intestinal goblet cells: 90.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.2" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020398, CAB033483, HPA062050" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Intestine - Digestion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Vesicles "Golgi apparatus" "CAB033483: AB_1119945, HPA020398: AB_2670429, HPA062050: " "unprognostic (2.64e-1)" "unprognostic (1.20e-1)" "unprognostic (2.60e-2)" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.49e-2)" "unprognostic (3.36e-2)" "unprognostic (2.30e-2)" "unprognostic (4.61e-2)" "unprognostic (3.44e-2)" "unprognostic (9.10e-2)" "unprognostic (1.60e-1)" "unprognostic (5.97e-5)" "unprognostic (1.51e-1)" "unprognostic (2.08e-1)" "unprognostic (4.60e-2)" "unprognostic (2.16e-1)" CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800652 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 38.2;intestine: 49.5;skin 1: 41.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 128.3;Gastric mucus-secreting cells: 55.4;Paneth cells: 99.9;Proximal enterocytes: 159.3;Undifferentiated cells: 53.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 6 Nucleoplasm Aggresome "CAB008087: AB_2228531, HPA035266: AB_2674542" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" CCDC33 "CT61, FLJ32855" ENSG00000140481 "Coiled-coil domain containing 33" Q8N5R6 15 74202705-74336472 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "fallopian tube: 18.4;testis: 19.6" "Cell type enhanced" "Detected in some" "Ciliated cells: 118.5;Early spermatids: 49.1;Ionocytes: 26.5;Late spermatids: 60.7" "Group enriched" "Detected in some" 5 "endometrial cancer: 1.4;ovarian cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.0" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 9.6" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" 10 "unprognostic (1.11e-2)" "unprognostic (5.53e-2)" "unprognostic (3.57e-1)" "unprognostic (5.13e-3)" "unprognostic (6.37e-3)" "unprognostic (2.16e-1)" "unprognostic (3.16e-3)" "unprognostic (3.68e-2)" "unprognostic (9.87e-2)" "unprognostic (2.05e-2)" "unprognostic (4.46e-1)" "unprognostic (4.18e-2)" "unprognostic (6.12e-2)" "unprognostic (9.37e-2)" CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 896.3;Basal respiratory cells: 481.5;Secretory cells: 448.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000024, HPA027802" Uncertain Supported Nucleoplasm Yes No "Cluster 32: Basophils - Transcription" "Cluster 13: Skin - Cornification" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Non-specific - Mixed function" 13 Nucleoplasm "CAB000024: AB_563678, HPA027802: AB_2672390" "unprognostic (4.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.38e-1)" "unprognostic (2.53e-2)" "unprognostic (9.46e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (4.39e-2)" "unprognostic (2.61e-3)" "unprognostic (4.38e-3)" "unprognostic (1.16e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" CD2AP CMS ENSG00000198087 "CD2 associated protein" Q9Y5K6 6 47477789-47627263 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003267, HPA003326, CAB004352" Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 58000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 28: Dendritic cells - Antigen presentation" 11 "Plasma membrane" "Centriolar satellite" "CAB004352: AB_627009, HPA003267: AB_1078458, HPA003326: AB_1078457" "unprognostic (5.98e-2)" "unprognostic (1.08e-2)" "unprognostic (1.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.31e-1)" "unprognostic (1.77e-2)" "unprognostic (1.74e-3)" "unprognostic (1.19e-1)" "unprognostic (6.71e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (5.53e-5)" "unprognostic (2.21e-1)" "unprognostic (3.09e-3)" "unprognostic (6.12e-3)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "prognostic favorable (7.57e-5)" CDCP1 "CD318, SIMA135" ENSG00000163814 "CUB domain containing protein 1" Q9H5V8 3 45082277-45146422 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 111.9;Basal respiratory cells: 87.9;Suprabasal keratinocytes: 73.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 26.9" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.3;NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Heart muscle - Macrophages, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010978, HPA010979, CAB025637" Enhanced "Intracellular and membrane" "No annotated function" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "CAB025637: , HPA010978: AB_1846403, HPA010979: AB_1846401" "unprognostic (9.31e-2)" "unprognostic (4.50e-2)" "unprognostic (1.67e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (1.41e-5)" "unprognostic (2.15e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.48e-4)" "unprognostic (2.14e-2)" "unprognostic (9.98e-3)" "unprognostic (3.59e-2)" "unprognostic (2.99e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" CDHR2 "FLJ20124, FLJ20383, PC-LKC, PCDH24, PCLKC" ENSG00000074276 "Cadherin related family member 2" Q9BYE9 5 176542511-176595974 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 262.0" "Group enriched" "Detected in some" 4 "Late spermatids: 695.5;Proximal enterocytes: 492.7" "Group enriched" "Detected in many" 14 "colorectal cancer: 9.1;liver cancer: 5.7;pancreatic cancer: 11.7;renal cancer: 8.6;stomach cancer: 9.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 4.1;Gastric cancer: 5.9;liver cancer: 3.9;pancreatic cancer: 9.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Region enriched" "Detected in single" 6 "hypothalamus: 2.2" "Low region specificity" "Detected in all" "HPA012569, HPA017053" Enhanced NA NA 8800000 "Cluster 25: Small intestine - Absorption" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" 2 "HPA012569: AB_1845298, HPA017053: AB_1845297" "unprognostic (1.34e-2)" "unprognostic (8.90e-4)" "unprognostic (3.82e-2)" "unprognostic (8.51e-2)" "unprognostic (5.10e-4)" "unprognostic (4.24e-3)" "unprognostic (6.66e-2)" "unprognostic (2.06e-3)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (7.66e-3)" "unprognostic (1.75e-1)" "prognostic favorable (9.29e-4)" "unprognostic (6.58e-2)" "unprognostic (3.55e-1)" "unprognostic (2.30e-2)" "unprognostic (1.42e-1)" CDS1 ENSG00000163624 "CDP-diacylglycerol synthase 1" Q92903 4 84583127-84651334 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 186.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036187, HPA064546" Enhanced NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Ciliated cells - Cilium assembly" 5 "HPA036187: AB_10601797, HPA064546: AB_2732714" "unprognostic (8.74e-2)" "unprognostic (7.11e-2)" "prognostic favorable (5.22e-4)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "unprognostic (3.11e-1)" "unprognostic (2.62e-1)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (6.67e-2)" "prognostic favorable (0.00e+0)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-1)" "unprognostic (2.06e-1)" CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 949.3" "Group enriched" "Detected in some" 8 "Distal enterocytes: 1949.2;Intestinal goblet cells: 820.7;Paneth cells: 991.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 196.8;Gallbladder cancer: 484.8" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Thyroid - Parafollicular cells" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 23000000 "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" CENPV "CENP-V, p30, PRR6" ENSG00000166582 "Centromere protein V" Q7Z7K6 17 16342534-16353656 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Paneth cells: 91.7;Proximal enterocytes: 101.9;Spermatocytes: 92.5;Spermatogonia: 117.2;Undifferentiated cells: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA042529, HPA042616" Enhanced Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 14 Nucleoplasm "Midbody, Cytosol" "HPA042529: AB_10793882, HPA042616: AB_10794050" "unprognostic (7.64e-2)" "unprognostic (4.41e-2)" "unprognostic (5.92e-2)" "unprognostic (9.66e-3)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (6.47e-2)" "unprognostic (1.21e-1)" "unprognostic (4.00e-2)" "unprognostic (7.73e-3)" "unprognostic (7.93e-2)" "unprognostic (4.09e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-2)" "unprognostic (2.54e-2)" "unprognostic (3.60e-3)" CFAP73 "CCDC42B, MIA2" ENSG00000186710 "Cilia and flagella associated protein 73" A6NFT4 12 113149724-113159276 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 30.5;fallopian tube: 41.0" "Cell type enriched" "Detected in some" 9 "Ciliated cells: 148.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.1" "Breast - Breast glandular cells (progenitors), Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA048539 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 6: Leukemia - Signal transduction" "Cluster 42: Ciliated cells - Cilium assembly" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA048539: AB_2680434" "unprognostic (2.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.90e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.18e-3)" "unprognostic (6.49e-2)" "unprognostic (2.94e-1)" "unprognostic (1.33e-1)" "unprognostic (3.14e-1)" "unprognostic (5.68e-2)" "unprognostic (3.43e-2)" "unprognostic (1.62e-4)" "unprognostic (2.03e-4)" "unprognostic (1.60e-1)" "unprognostic (4.03e-2)" "unprognostic (1.55e-2)" CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 54.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 177.3;Alveolar cells type 2: 57.9;Distal enterocytes: 113.1;Mesothelial cells: 81.6;Proximal enterocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 3 "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: AB_10600208, HPA027587: AB_10601884, HPA027657: AB_10611527" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.74e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (4.61e-1)" "unprognostic (2.11e-2)" "unprognostic (2.96e-3)" "unprognostic (7.10e-2)" "prognostic favorable (5.84e-10)" "unprognostic (2.66e-1)" "unprognostic (3.00e-1)" "unprognostic (8.28e-2)" "unprognostic (2.10e-2)" CHMP4C "MGC22825, Shax3, VPS32C" ENSG00000164695 "Charged multivesicular body protein 4C" Q96CF2 8 81732448-81759515 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.7" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 79.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.9" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023763, HPA023799" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 2 "Microtubules, Cytokinetic bridge" "HPA023763: , HPA023799: AB_1846670" "unprognostic (3.98e-2)" "unprognostic (6.75e-3)" "unprognostic (1.58e-1)" "unprognostic (5.19e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (9.33e-5)" "unprognostic (7.54e-2)" "unprognostic (8.08e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.99e-2)" "prognostic favorable (1.96e-6)" "unprognostic (3.29e-3)" "unprognostic (4.95e-1)" "unprognostic (2.67e-1)" "prognostic favorable (6.45e-4)" CKMT1A CKMT1 ENSG00000223572 "Creatine kinase, mitochondrial 1A" P12532 15 43692886-43699222 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.7;esophagus: 81.5;intestine: 72.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 66.6;Distal enterocytes: 151.6;Enteroendocrine cells: 75.9;Paneth cells: 63.3;Proximal enterocytes: 79.8;Syncytiotrophoblasts: 77.2;Undifferentiated cells: 81.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA043491 Uncertain "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 10 "HPA043491: AB_2678510" "unprognostic (2.04e-2)" "unprognostic (2.53e-2)" "unprognostic (1.17e-1)" "unprognostic (4.02e-3)" "unprognostic (3.80e-1)" "unprognostic (7.44e-2)" "unprognostic (2.21e-1)" "unprognostic (3.10e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.51e-2)" "unprognostic (3.78e-9)" "unprognostic (3.52e-2)" "unprognostic (1.03e-1)" "unprognostic (7.37e-2)" "unprognostic (1.73e-3)" CKMT1B "CKMT, CKMT1, UMTCK" ENSG00000237289 "Creatine kinase, mitochondrial 1B" P12532 15 43593054-43604901 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.7;esophagus: 72.2;intestine: 78.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 109.4;Distal enterocytes: 198.6;Enteroendocrine cells: 79.9;Intestinal goblet cells: 75.9;Paneth cells: 69.9;Proximal enterocytes: 122.2;Syncytiotrophoblasts: 107.6;Undifferentiated cells: 93.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA043491 Uncertain "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 10 "HPA043491: AB_2678510" "unprognostic (3.47e-2)" "unprognostic (9.73e-3)" "unprognostic (3.10e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (1.29e-1)" "unprognostic (1.96e-1)" "unprognostic (5.19e-2)" "unprognostic (2.84e-1)" "unprognostic (3.64e-1)" "unprognostic (5.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-2)" "unprognostic (2.26e-8)" "unprognostic (1.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.43e-2)" "unprognostic (4.36e-2)" CLDN18 SFTPJ ENSG00000066405 "Claudin 18" P56856 3 137998735-138033655 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 51 "lung: 244.4;stomach 1: 706.2" "Group enriched" "Detected in some" 32 "Alveolar cells type 1: 661.9;Alveolar cells type 2: 361.3;Gastric mucus-secreting cells: 1092.4" "Group enriched" "Detected in some" 11 "pancreatic cancer: 113.6;stomach cancer: 186.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 17.9;pancreatic cancer: 12.4" "Lung - Alveolar cells type 1, Stomach - Gastric mucous cells, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013010, CAB013243, HPA018446" Enhanced Approved "Cell Junctions" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 17: Choroid plexus - Cilium" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Non-specific - Mixed function" 2 "Cell Junctions" "CAB013010: AB_2533382, CAB013243: AB_2533383, HPA018446: AB_2669866" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (2.93e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (8.51e-2)" "unprognostic (5.14e-4)" "unprognostic (2.00e-1)" "unprognostic (1.29e-1)" "unprognostic (2.60e-1)" "unprognostic (9.54e-2)" "unprognostic (1.38e-2)" "unprognostic (4.42e-5)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (8.26e-2)" "unprognostic (2.95e-1)" CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.9;stomach 1: 15.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 337.6;Gastric mucus-secreting cells: 61.9;Paneth cells: 183.6;Proximal enterocytes: 99.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "choroid plexus: 4.6" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 5: Enterocytes - Absorption" 1 Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 37.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 95.2;Distal enterocytes: 76.5;Rod photoreceptor cells: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 39: Retina & Testis - Cilium" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" CORO2A "IR10, WDR2" ENSG00000106789 "Coronin 2A" Q92828 9 98120975-98192637 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 48.2;Club cells: 48.2;Distal enterocytes: 79.2;Ionocytes: 48.6;Proximal enterocytes: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 11.4;monocytes: 7.8;T-cells: 11.9" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041161, HPA041302" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 45: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 3 "Plasma membrane, Cytosol" "HPA041161: AB_10795537, HPA041302: AB_10794195" "unprognostic (4.49e-3)" "unprognostic (3.44e-2)" "unprognostic (3.14e-1)" "unprognostic (1.78e-1)" "unprognostic (3.39e-3)" "unprognostic (1.64e-1)" "unprognostic (3.73e-2)" "unprognostic (5.73e-2)" "unprognostic (2.79e-1)" "unprognostic (1.52e-1)" "unprognostic (4.50e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" "unprognostic (6.40e-3)" COTL1 CLP ENSG00000103187 "Coactosin like F-actin binding protein 1" Q14019 16 84565596-84618078 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Chaperone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 365.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1658.8;Hofbauer cells: 861.6;Kupffer cells: 848.6;Langerhans cells: 1303.9;Macrophages: 857.5;monocytes: 3363.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 2442.3;eosinophil: 3426.1;intermediate monocyte: 4071.9;myeloid DC: 2397.3;neutrophil: 1764.5;non-classical monocyte: 4600.6" "Group enriched" "Detected in all" 5 "dendritic cells: 2397.3;granulocytes: 3426.1;monocytes: 4600.6" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008918, CAB062328" Enhanced Supported Cytosol NA NA 10000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Monocytes - Innate immune response" 3 Cytosol "CAB062328: AB_2084785, HPA008918: AB_2668176" "unprognostic (2.93e-2)" "unprognostic (1.11e-1)" "unprognostic (3.27e-2)" "unprognostic (2.38e-1)" "unprognostic (3.21e-3)" "unprognostic (8.95e-2)" "unprognostic (2.43e-1)" "unprognostic (1.14e-1)" "unprognostic (7.70e-2)" "unprognostic (5.99e-2)" "unprognostic (5.43e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.26e-1)" "unprognostic (5.48e-2)" "unprognostic (7.73e-2)" "unprognostic (3.35e-3)" CRB3 MGC17303 ENSG00000130545 "Crumbs cell polarity complex component 3" Q9BUF7 19 6463777-6467221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 167.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 14.1" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 9.2" "Group enriched" "Detected in many" 21 "B-cells: 3.1;T-cells: 9.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA013835 Enhanced Supported "Cell Junctions" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Cell Junctions" "HPA013835: AB_1847214" "unprognostic (3.25e-1)" "unprognostic (4.41e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.54e-4)" "unprognostic (1.24e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-2)" "unprognostic (1.86e-1)" "unprognostic (2.57e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.42e-3)" "unprognostic (1.96e-1)" "unprognostic (1.12e-2)" "prognostic favorable (8.06e-5)" CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 118.6;Squamous epithelial cells: 145.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.8;intermediate monocyte: 9.4;myeloid DC: 6.4;non-classical monocyte: 5.8" "Group enriched" "Detected in many" 19 "dendritic cells: 6.4;monocytes: 9.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 5 "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" CTSE ENSG00000196188 "Cathepsin E" P14091 1 206008535-206023909 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 1138.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 553.6;Alveolar cells type 2: 190.6;Exocrine glandular cells: 130.0;Gastric mucus-secreting cells: 626.1;Paneth cells: 256.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 297.4;stomach cancer: 200.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 28.4;Esophageal cancer: 48.8;Gastric cancer: 110.7;pancreatic cancer: 35.3" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA012674, HPA012940, CAB032687" Enhanced Approved Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" Vesicles "CAB032687: AB_637901, HPA012674: , HPA012940: AB_2668773" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-2)" "unprognostic (2.72e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-3)" "unprognostic (1.45e-1)" "unprognostic (3.29e-2)" "unprognostic (2.87e-2)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "unprognostic (6.37e-3)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (2.61e-2)" "prognostic favorable (5.26e-5)" CWH43 "CWH43-C, FLJ21511, PGAP2IP" ENSG00000109182 "Cell wall biogenesis 43 C-terminal homolog" Q9H720 4 48986275-49062081 "Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.3;prostate: 41.4;skin 1: 24.8" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.5;Ciliated cells: 34.1;Distal enterocytes: 25.3;Glandular and luminal cells: 20.5;Prostatic glandular cells: 80.5;Suprabasal keratinocytes: 65.9" "Cancer enriched" "Detected in many" 4 "prostate cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 29 "prostate cancer: 16.8" "Colon - Colon enterocytes, Kidney - Intercalated cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042814, HPA048140" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 60: Prostate cancer - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" "Golgi apparatus, Plasma membrane" "HPA042814: AB_2678182, HPA048140: AB_2680280" "unprognostic (9.38e-3)" "unprognostic (6.23e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.32e-4)" "unprognostic (2.14e-1)" "unprognostic (5.00e-2)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.29e-11)" "unprognostic (5.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.82e-2)" "unprognostic (2.51e-2)" CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 1667.6" "Cell type enriched" "Detected in some" 32 "Hepatocytes: 1605.5" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.6;liver cancer: 1.4;prostate cancer: 1.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 31: Liver - Plasma proteins" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favorable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 86.5;intestine: 81.0;liver: 141.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 109.3;Cytotrophoblasts: 115.0;Oligodendrocytes: 63.7;Proximal enterocytes: 116.3;Syncytiotrophoblasts: 252.2" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.3" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" Enzyme NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Cytotrophoblasts - Mitochondria" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 98.4;stomach 1: 117.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 90.2;Intestinal goblet cells: 34.6;Langerhans cells: 82.1;Proximal enterocytes: 41.7;Schwann cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.8;myeloid DC: 84.5" "Group enriched" "Detected in many" 131 "dendritic cells: 84.5;monocytes: 24.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Heart muscle - Macrophages, Liver - Kupffer cells, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Small intestine - Absorption" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 28: Dendritic cells - Antigen presentation" 2 "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 172.8;liver: 269.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 396.8;Distal enterocytes: 264.5;Gastric mucus-secreting cells: 525.3;Hepatocytes: 410.7;Proximal enterocytes: 1064.2" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Colon - Colon enterocytes, Liver - Hepatocytes, Stomach - Gastric mucous cells" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" CYP4F3 "CYP4F, LTB4H" ENSG00000186529 "Cytochrome P450 family 4 subfamily F member 3" Q08477 19 15640897-15662825 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 79.4;liver: 230.0" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 442.9" "Cancer enhanced" "Detected in many" "liver cancer: 30.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 63 "neutrophil: 84.2" "Lineage enriched" "Detected in single" 179 "granulocytes: 84.2" "Cancer enriched" "Detected in many" 7 "Gallbladder cancer: 102.4" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Thyroid - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA058960 Approved NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "HPA058960: AB_2683862" "unprognostic (1.73e-2)" "unprognostic (9.70e-3)" "unprognostic (1.21e-1)" "unprognostic (1.16e-3)" "unprognostic (5.40e-1)" "unprognostic (1.57e-1)" "unprognostic (7.15e-3)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (3.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.32e-1)" "unprognostic (1.59e-3)" "unprognostic (2.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.07e-2)" "unprognostic (2.07e-1)" CYSTM1 "C5orf32, ORF1-FL49" ENSG00000120306 "Cysteine rich transmembrane module containing 1" Q9H1C7 5 140175156-140282052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 1282.0" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1271.0;Distal tubular cells: 2259.0;Gastric mucus-secreting cells: 2148.3;Late spermatids: 1672.2;Proximal tubular cells: 1230.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 427.5" "Lineage enriched" "Detected in all" 7 "granulocytes: 427.5" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050930 Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 2 "HPA050930: AB_2681278" "unprognostic (7.39e-2)" "unprognostic (3.68e-2)" "unprognostic (4.46e-2)" "prognostic favorable (1.31e-4)" "unprognostic (5.38e-2)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.71e-4)" "unprognostic (2.26e-1)" "unprognostic (1.12e-1)" "unprognostic (2.73e-1)" "unprognostic (2.53e-1)" "unprognostic (2.24e-1)" "prognostic favorable (9.69e-5)" "unprognostic (7.63e-2)" "unprognostic (2.23e-1)" "unprognostic (4.67e-2)" "unprognostic (1.14e-2)" DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA057194" Approved Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" Receptor NA NA 4400000 "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Nucleoplasm, Cell Junctions" "CAB010162: AB_2092090, CAB025656: , HPA057194: " "unprognostic (2.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.75e-3)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (4.41e-2)" "prognostic favorable (3.31e-10)" "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (5.49e-3)" "unprognostic (4.09e-2)" DENND11 "KIAA1147, LCHN" ENSG00000257093 "DENN domain containing 11" A4D1U4 7 141656728-141702166 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Muller glia cells: 90.8;Oligodendrocytes: 86.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 1.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029467, HPA061437" Approved Approved "Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 34: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Muller glia cells - Visual perception" "Golgi apparatus" "HPA029467: AB_10602915, HPA061437: AB_2684517" "unprognostic (1.27e-1)" "unprognostic (5.68e-2)" "unprognostic (7.05e-2)" "unprognostic (1.77e-1)" "unprognostic (4.44e-2)" "prognostic favorable (6.24e-4)" "unprognostic (6.49e-2)" "unprognostic (3.63e-2)" "unprognostic (3.02e-2)" "unprognostic (4.27e-1)" "unprognostic (7.62e-2)" "unprognostic (3.75e-2)" "prognostic favorable (8.01e-4)" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.91e-3)" "unprognostic (1.78e-1)" DIAPH1 "DFNA1, hDIA1, LFHL1, mDia1" ENSG00000131504 "Diaphanous related formin 1" O60610 5 141515016-141619055 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing Actin-binding "Cancer-related genes, Deafness, Disease variant, Epilepsy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 165.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004916, HPA076913" Approved Uncertain "Plasma membrane,Cytosol" NA NA 2000000 "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 45: Non-specific - Mixed function" 5 "Plasma membrane, Cytosol" "HPA004916: AB_1847668, HPA076913: " "unprognostic (6.79e-2)" "unprognostic (2.99e-1)" "unprognostic (2.12e-3)" "unprognostic (3.73e-2)" "unprognostic (4.18e-2)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (4.54e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "prognostic unfavorable (7.81e-5)" "unprognostic (2.88e-3)" "prognostic favorable (1.29e-5)" "unprognostic (1.64e-2)" "unprognostic (1.84e-2)" "unprognostic (7.00e-2)" "unprognostic (1.65e-1)" DOK4 FLJ10488 ENSG00000125170 "Docking protein 4" Q8TEW6 16 57471922-57487327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 98.3;Paneth cells: 70.4;Proximal enterocytes: 88.3;Proximal tubular cells: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Neuroblastoma: 186.7" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008348, HPA055849" Supported Approved Cytosol NA No "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 5: Enterocytes - Absorption" 8 Cytosol "HPA008348: , HPA055849: AB_2682942" "unprognostic (3.44e-2)" "unprognostic (2.04e-2)" "unprognostic (1.17e-1)" "unprognostic (4.73e-2)" "unprognostic (3.66e-1)" "unprognostic (9.71e-2)" "unprognostic (5.35e-2)" "unprognostic (1.39e-1)" "unprognostic (1.13e-2)" "unprognostic (3.00e-2)" "unprognostic (2.27e-2)" "unprognostic (1.53e-1)" "unprognostic (2.58e-3)" "unprognostic (4.30e-2)" "unprognostic (2.21e-1)" "unprognostic (4.42e-3)" "unprognostic (1.18e-3)" DOP1B "C21orf5, DOPEY2, KIAA0933" ENSG00000142197 "DOP1 leucine zipper like protein B" Q9Y3R5 21 36156782-36294274 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 61.6;Gastric mucus-secreting cells: 53.6;Intestinal goblet cells: 80.2;Prostatic glandular cells: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072065 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 23: B-cells - Immunoglobulins" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm Mitochondria "HPA072065: AB_2686486" "prognostic unfavorable (7.08e-4)" "unprognostic (7.68e-2)" "unprognostic (2.50e-2)" "unprognostic (1.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.66e-2)" "unprognostic (1.04e-2)" "unprognostic (1.01e-1)" "unprognostic (2.38e-1)" "unprognostic (1.36e-1)" "unprognostic (3.13e-2)" "unprognostic (4.35e-2)" "unprognostic (3.01e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (2.85e-1)" DQX1 FLJ23757 ENSG00000144045 "DEAQ-box RNA dependent ATPase 1" Q8TE96 2 74518131-74526281 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 15.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 20.0;Gastric mucus-secreting cells: 15.9;Intestinal goblet cells: 16.2;Paneth cells: 19.0;Proximal enterocytes: 41.4;Undifferentiated cells: 8.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.5" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA039158, HPA046763" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoli fibrillar center" "HPA039158: AB_10960125, HPA046763: " "unprognostic (2.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (9.95e-2)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-1)" "unprognostic (4.54e-2)" "unprognostic (1.68e-1)" "unprognostic (7.67e-2)" "unprognostic (2.21e-2)" "unprognostic (0.00e+0)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-3)" DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 165.7;vagina: 94.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 467.2;Distal enterocytes: 308.6;Squamous epithelial cells: 821.6;Suprabasal keratinocytes: 1501.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 29.9;neutrophil: 8.4" "Lineage enriched" "Detected in many" 14 "granulocytes: 29.9" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 24000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Plasma membrane" "Endoplasmic reticulum" "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" DUOX2 "LNOX2, P138-TOX, P138(TOX), THOX2" ENSG00000140279 "Dual oxidase 2" Q9NRD8 15 45092650-45114172 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 280.6;thyroid gland: 73.4;urinary bladder: 89.6" "Group enriched" "Detected in many" 4 "Ductal cells: 271.7;Exocrine glandular cells: 350.5;Gastric mucus-secreting cells: 90.8" "Cancer enhanced" "Detected in many" "thyroid cancer: 60.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.9;Esophageal cancer: 2.2;head and neck cancer: 3.4" "Prostate - Urothelial cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "unprognostic (3.19e-1)" "unprognostic (7.51e-2)" "unprognostic (3.77e-2)" "unprognostic (5.99e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (7.93e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.49e-2)" "unprognostic (9.59e-3)" "unprognostic (7.11e-2)" "unprognostic (5.32e-5)" "unprognostic (1.71e-1)" "unprognostic (1.62e-2)" "unprognostic (4.12e-2)" "unprognostic (1.63e-2)" DUOXA2 ENSG00000140274 "Dual oxidase maturation factor 2" Q1HG44 15 45114326-45118421 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Protein transport, Transport" "Congenital hypothyroidism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 61.7;urinary bladder: 40.4" "Group enriched" "Detected in some" 7 "Ductal cells: 935.0;Exocrine glandular cells: 806.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 27.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA063548 Enhanced NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 1 "HPA063548: AB_2685037" "unprognostic (1.87e-1)" "unprognostic (9.88e-2)" "unprognostic (7.37e-2)" "unprognostic (6.45e-2)" "unprognostic (1.72e-1)" "unprognostic (2.00e-3)" "unprognostic (6.73e-2)" "unprognostic (2.03e-1)" "unprognostic (2.10e-1)" "unprognostic (3.15e-2)" "unprognostic (1.26e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-4)" "unprognostic (9.75e-2)" "unprognostic (3.11e-1)" "unprognostic (1.37e-1)" "unprognostic (5.54e-2)" EBP "CDPX2, CHO2, CPX, CPXD" ENSG00000147155 "EBP cholestenol delta-isomerase" Q15125 X 48521799-48528716 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Cataract, Disease variant, Dwarfism, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 318.4" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 242.4;Hepatocytes: 634.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003130 Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Hepatocytes - Metabolism" 159 "Nuclear membrane, Endoplasmic reticulum" "HPA003130: AB_1078717" "unprognostic (1.90e-1)" "unprognostic (2.64e-2)" "unprognostic (2.80e-1)" "unprognostic (6.27e-2)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (4.72e-2)" "unprognostic (1.47e-1)" "unprognostic (5.14e-2)" "unprognostic (4.04e-2)" "unprognostic (5.39e-2)" "unprognostic (4.13e-1)" "unprognostic (1.36e-1)" EEF1A2 "EEF1AL, HS1, STN, STNL" ENSG00000101210 "Eukaryotic translation elongation factor 1 alpha 2" Q05639 20 63488013-63499239 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 1680.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 128.1;Horizontal cells: 186.3;Skeletal myocytes: 604.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034019, HPA051759, HPA053862, HPA056990" Approved Approved Nucleoli,Cytosol NA NA 55000000 "Cluster 79: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 2: Skeletal myocytes - Muscle contraction" 6 Cytosol Nucleoli "CAB034019: AB_1562672, HPA051759: AB_2681595, HPA053862: AB_2797248, HPA056990: AB_2683302" "unprognostic (1.40e-2)" "unprognostic (6.82e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (2.90e-5)" "unprognostic (5.17e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (4.85e-1)" "unprognostic (1.68e-1)" "unprognostic (3.02e-2)" "unprognostic (1.74e-2)" "unprognostic (2.20e-2)" "unprognostic (2.30e-1)" "unprognostic (1.86e-1)" "unprognostic (8.29e-3)" "unprognostic (1.82e-1)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" EFHD2 MGC4342 ENSG00000142634 "EF-hand domain family member D2" Q96C19 1 15409888-15430339 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 444.7;NK-cells: 481.5;Proximal enterocytes: 290.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 133.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Macrophages, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048961 Enhanced Approved Cytosol No No 220000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Cytosol "HPA048961: AB_2680572" "unprognostic (1.37e-3)" "unprognostic (3.69e-1)" "unprognostic (7.83e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (9.11e-2)" "unprognostic (9.61e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (6.31e-9)" "unprognostic (2.71e-2)" "unprognostic (9.71e-2)" "prognostic favorable (2.70e-4)" "prognostic favorable (3.60e-5)" ELF4 "ELFR, MEF" ENSG00000102034 "E74 like ETS transcription factor 4" Q99607 X 130063955-130110716 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 37.6;monocytes: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058595, HPA060277" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 37: Glandular & Luminal cells - Unknown function" "Nuclear bodies" Nucleoplasm "HPA058595: AB_2683768, HPA060277: AB_2684239" "unprognostic (1.33e-1)" "unprognostic (8.51e-2)" "unprognostic (3.83e-1)" "unprognostic (2.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (4.43e-3)" "unprognostic (7.86e-3)" "unprognostic (3.50e-2)" "unprognostic (1.80e-1)" "unprognostic (1.29e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (6.49e-6)" "unprognostic (1.43e-1)" "unprognostic (5.46e-2)" "unprognostic (2.51e-1)" "prognostic favorable (1.42e-4)" ELOVL6 "FLJ23378, LCE, MGC5487" ENSG00000170522 "ELOVL fatty acid elongase 6" Q9H5J4 4 110045846-110199199 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 35.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.6;Hepatocytes: 89.8;Inhibitory neurons: 75.2;Oligodendrocytes: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 2.4;MAIT T-cell: 2.6;memory CD4 T-cell: 1.0;memory CD8 T-cell: 1.3;naive CD8 T-cell: 1.0;NK-cell: 3.3" "Group enriched" "Detected in many" 21 "NK-cells: 3.3;T-cells: 2.6" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042355 Uncertain NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 62: Hepatocytes - Metabolism" 3 "HPA042355: AB_10796577" "unprognostic (3.92e-2)" "unprognostic (9.47e-2)" "prognostic favorable (6.74e-4)" "unprognostic (8.09e-2)" "unprognostic (2.06e-2)" "unprognostic (1.08e-3)" "unprognostic (4.16e-1)" "unprognostic (3.01e-3)" "unprognostic (4.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.33e-1)" "unprognostic (1.90e-2)" "unprognostic (2.28e-2)" "unprognostic (1.21e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (5.32e-2)" EPCAM "17-1A, 323/A3, Ber-Ep4, BerEp4, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC-31, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 780.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2590.4;Intestinal goblet cells: 1370.3;Paneth cells: 2221.3;Proximal enterocytes: 2597.5;Undifferentiated cells: 1520.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 762.9" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 5 "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" EPS8L1 "DRC3, FLJ20258, MGC23164, MGC4642" ENSG00000131037 "EPS8 like 1" Q8TE68 19 55072020-55087923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 120.8;skin 1: 57.8" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 504.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041851, HPA043545" Uncertain Supported Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 15: Kidney cancer - Membrane components" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 3 Cytosol "HPA041851: AB_2677706, HPA043545: AB_2678544" "unprognostic (1.91e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (7.18e-2)" "unprognostic (9.33e-2)" "unprognostic (2.54e-2)" "unprognostic (4.61e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.43e-2)" "unprognostic (5.84e-3)" "unprognostic (2.65e-2)" "unprognostic (3.85e-3)" "unprognostic (5.04e-3)" "unprognostic (3.02e-1)" "unprognostic (5.41e-3)" "unprognostic (2.63e-1)" EPS8L3 "FLJ21522, MGC16817" ENSG00000198758 "EPS8 like 3" Q8TE67 1 109750080-109764027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 34.5;intestine: 138.1;stomach 1: 49.5" "Group enriched" "Detected in some" 8 "Distal enterocytes: 190.9;Enteroendocrine cells: 77.6;Gastric mucus-secreting cells: 74.9;Intestinal goblet cells: 90.7;Late spermatids: 151.0;Paneth cells: 125.1;Proximal enterocytes: 277.0;Undifferentiated cells: 72.7" "Group enriched" "Detected in many" 6 "colorectal cancer: 52.5;pancreatic cancer: 29.7;stomach cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 65.2;Gastric cancer: 30.1" "Colon - Colon enterocytes, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA030998 Approved Approved Vesicles NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA030998: AB_2673691" "unprognostic (1.73e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.13e-5)" "unprognostic (5.55e-3)" "unprognostic (3.71e-2)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.87e-3)" "unprognostic (3.89e-1)" "prognostic favorable (1.82e-4)" ERN2 IRE1b ENSG00000134398 "Endoplasmic reticulum to nucleus signaling 2" Q76MJ5 16 23690310-23713226 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Hydrolase, Kinase, Multifunctional enzyme, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 18.7;gallbladder: 16.4;intestine: 28.0;salivary gland: 22.2;stomach 1: 50.5" "Cell type enhanced" "Detected in some" "Club cells: 56.5;Distal enterocytes: 92.0;Enteroendocrine cells: 39.6;Gastric mucus-secreting cells: 159.2;Intestinal goblet cells: 147.0;Ionocytes: 59.6;Undifferentiated cells: 37.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.0;pancreatic cancer: 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 13.3;colorectal cancer: 19.5;Gallbladder cancer: 8.9;Gastric cancer: 16.2;pancreatic cancer: 8.7" "Breast - Adipocytes (Breast), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA076875 Approved Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Transcription NA NA "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "Endoplasmic reticulum, Cytosol" "HPA076875: " "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (3.45e-1)" "unprognostic (2.98e-2)" "unprognostic (3.83e-2)" "unprognostic (1.13e-2)" "unprognostic (7.67e-4)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (7.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-9)" "unprognostic (1.48e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.13e-3)" ESRP2 "FLJ21918, RBM35B" ENSG00000103067 "Epithelial splicing regulatory protein 2" Q9H6T0 16 68229033-68238102 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 53.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.9;Gastric mucus-secreting cells: 37.1;Late spermatids: 76.8;Syncytiotrophoblasts: 59.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040751, HPA048597, HPA048618" Uncertain Enhanced Nucleoplasm NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" Nucleoplasm "HPA040751: AB_2677115, HPA048597: AB_2680458, HPA048618: AB_2680463" "unprognostic (3.55e-2)" "unprognostic (1.18e-1)" "unprognostic (1.19e-1)" "unprognostic (3.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.62e-2)" "unprognostic (1.54e-1)" "unprognostic (1.33e-1)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (8.80e-2)" "prognostic favorable (1.30e-6)" "unprognostic (1.24e-1)" "unprognostic (3.16e-1)" "unprognostic (9.04e-3)" "unprognostic (8.75e-3)" ESRRA "ERR1, ERRa, ERRalpha, ESRL1, NR3B1" ENSG00000173153 "Estrogen related receptor alpha" P11474 11 64305497-64316743 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 188.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 162.0;Hepatocytes: 249.3;Kupffer cells: 167.7;Proximal enterocytes: 181.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053785, HPA077297" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Cytokinetic bridge" Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 35: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 7 "Nucleoplasm, Nucleoli fibrillar center, Microtubules" "Cytokinetic bridge" "HPA053785: AB_2682260, HPA077297: " "unprognostic (7.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (3.08e-1)" "unprognostic (7.24e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.98e-1)" "unprognostic (3.52e-2)" "unprognostic (2.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.34e-7)" "unprognostic (3.43e-3)" "unprognostic (3.19e-2)" "unprognostic (2.38e-2)" "unprognostic (7.20e-2)" ETNK1 "EKI, EKI1" ENSG00000139163 "Ethanolamine kinase 1" Q9HBU6 12 22625075-22690665 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 434.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010712, HPA029407" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 38: Non-specific - Transcription" "Cluster 21: Early spermatids - Spermatogenesis" 6 "Nucleoplasm, Plasma membrane, Cytosol" "HPA010712: AB_2668349, HPA029407: AB_2673026" "unprognostic (2.06e-1)" "unprognostic (7.48e-2)" "unprognostic (1.23e-3)" "unprognostic (2.19e-1)" "unprognostic (8.79e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.98e-3)" "unprognostic (8.30e-2)" "unprognostic (7.97e-3)" "unprognostic (2.01e-1)" "unprognostic (1.64e-2)" "unprognostic (4.53e-3)" "unprognostic (2.77e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-1)" "prognostic favorable (1.75e-4)" F11R "CD321, JAM-1, JAM-A, JAM1, JAMA, JCAM, PAM-1" ENSG00000158769 "F11 receptor" Q9Y624 1 160995211-161021343 "CD markers, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 200.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 166.2;neutrophil: 114.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 166.2" "Cancer enhanced" "Detected in all" "testis cancer: 214.6" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004671, HPA043616, HPA061700" Enhanced Supported "Cell Junctions,Microtubules" NA NA 1900000 "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 18 Microtubules "Cell Junctions" "CAB004671: AB_425964, HPA043616: , HPA061700: AB_2684589" "unprognostic (1.60e-2)" "unprognostic (5.78e-3)" "unprognostic (1.78e-3)" "unprognostic (2.24e-1)" "unprognostic (4.99e-2)" "unprognostic (4.89e-2)" "unprognostic (2.28e-1)" "unprognostic (2.55e-1)" "unprognostic (6.35e-2)" "unprognostic (1.98e-3)" "unprognostic (1.87e-2)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (2.50e-1)" "unprognostic (1.59e-1)" "unprognostic (9.72e-3)" "unprognostic (5.01e-2)" F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 57.4;stomach 1: 42.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 74.3;Distal enterocytes: 85.0;Gastric mucus-secreting cells: 74.3;Glandular and luminal cells: 66.8;Intestinal goblet cells: 51.9;Proximal enterocytes: 56.1;Suprabasal keratinocytes: 97.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 18.1" "Immune cell enhanced" "Detected in many" "neutrophil: 42.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.2" "Cancer enhanced" "Detected in many" "Bile duct cancer: 184.1" "Colon - Colon enterocytes, Heart muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Glandular & Luminal cells - Unknown function" 7 "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" FA2H "FAAH, FAXDC1, FLJ25287, SPG35" ENSG00000103089 "Fatty acid 2-hydroxylase" Q7L5A8 16 74712955-74774831 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 194.9;stomach 1: 59.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 83.7;Oligodendrocyte precursor cells: 57.5;Oligodendrocytes: 286.6;Paneth cells: 65.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056614, HPA077840" Approved Uncertain "Nuclear membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Oligodendrocytes - Unknown function" 25 "Nuclear membrane" "HPA056614: AB_2683191, HPA077840: AB_2686858" "unprognostic (1.33e-1)" "unprognostic (4.97e-2)" "unprognostic (9.19e-2)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (5.85e-2)" "unprognostic (1.48e-2)" "unprognostic (2.47e-2)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (6.01e-2)" "prognostic favorable (5.01e-6)" "unprognostic (1.50e-1)" "unprognostic (1.76e-1)" "unprognostic (1.83e-2)" "unprognostic (2.11e-3)" FAM102A "bA203J24.7, C9orf132, Eeig1, SYM-3A" ENSG00000167106 "Family with sequence similarity 102 member A" Q5T9C2 9 127940582-127980989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036030 Approved Cytosol NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 Cytosol "HPA036030: AB_10670675" "unprognostic (3.27e-1)" "unprognostic (1.66e-3)" "unprognostic (1.06e-3)" "unprognostic (4.69e-3)" "unprognostic (2.32e-1)" "unprognostic (1.21e-2)" "unprognostic (8.50e-2)" "unprognostic (2.97e-1)" "unprognostic (8.36e-2)" "unprognostic (1.01e-2)" "unprognostic (9.28e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (8.28e-3)" "unprognostic (6.98e-2)" FAM20A DKFZp434F2322 ENSG00000108950 "FAM20A golgi associated secretory pathway pseudokinase" Q96MK3 17 68535113-68601367 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 49.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.8;Hepatocytes: 56.0;Hofbauer cells: 81.0;Late spermatids: 197.5;Serous glandular cells: 98.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Adipose subcutaneous - Adipose progenitor cells, Colon - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048964 Approved "Secreted in other tissues" Other NA NA 13000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "HPA048964: AB_2680575" "unprognostic (3.68e-2)" "unprognostic (3.14e-2)" "unprognostic (3.35e-2)" "unprognostic (4.49e-3)" "unprognostic (6.56e-2)" "unprognostic (5.29e-2)" "unprognostic (3.90e-3)" "unprognostic (2.39e-2)" "unprognostic (4.15e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (9.16e-10)" "unprognostic (1.25e-3)" "unprognostic (1.06e-1)" "unprognostic (4.55e-2)" "unprognostic (2.39e-2)" FAM83B "C6orf143, FLJ30642" ENSG00000168143 "Family with sequence similarity 83 member B" Q5T0W9 6 54846771-54945099 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 14.1;skin 1: 25.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 45.6;Basal squamous epithelial cells: 40.1;Salivary duct cells: 20.7;Squamous epithelial cells: 35.2;Suprabasal keratinocytes: 49.4;Syncytiotrophoblasts: 26.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 15.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 12.9" "Colon - Colon enterocytes, Kidney - Endothelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA031464, HPA031465" Enhanced NA NA "Cluster 13: Skin - Cornification" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "HPA031464: AB_10599973, HPA031465: AB_10601566" "unprognostic (2.29e-1)" "unprognostic (3.93e-2)" "unprognostic (3.71e-2)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.48e-4)" "unprognostic (7.27e-2)" "unprognostic (5.77e-3)" "prognostic unfavorable (7.60e-4)" "unprognostic (1.62e-1)" "unprognostic (3.19e-2)" "unprognostic (1.85e-1)" "unprognostic (4.35e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.86e-5)" FAM83E FLJ20200 ENSG00000105523 "Family with sequence similarity 83 member E" Q2M2I3 19 48599961-48615076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 31.8;salivary gland: 27.7;stomach 1: 36.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 96.2;Enteroendocrine cells: 54.0;Gastric mucus-secreting cells: 126.2;Intestinal goblet cells: 167.4;Paneth cells: 65.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.3;Gastric cancer: 9.9" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049305, HPA075968" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 1 Cytosol Vesicles "HPA049305: AB_2680705, HPA075968: " "unprognostic (1.36e-1)" "unprognostic (9.81e-3)" "unprognostic (3.83e-2)" "unprognostic (7.39e-2)" "unprognostic (4.77e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (2.26e-2)" "unprognostic (3.18e-1)" "unprognostic (2.71e-1)" "unprognostic (8.00e-2)" "unprognostic (9.31e-2)" "unprognostic (7.05e-8)" "unprognostic (5.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.70e-1)" "unprognostic (8.90e-3)" FAM83H FLJ46072 ENSG00000180921 "Family with sequence similarity 83 member H" Q6ZRV2 8 143723933-143738234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 68.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 79.6;Alveolar cells type 2: 43.4;Squamous epithelial cells: 43.9;Suprabasal keratinocytes: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA024505, HPA024604" Enhanced Approved Cytosol NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 1 Cytosol "HPA024505: AB_1848417, HPA024604: AB_1848418" "unprognostic (3.80e-2)" "unprognostic (3.75e-3)" "unprognostic (6.87e-2)" "unprognostic (1.63e-2)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.93e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-3)" "unprognostic (3.95e-2)" "unprognostic (9.69e-3)" "prognostic favorable (4.42e-4)" "unprognostic (5.54e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" FBXW10B "CDRT1, FBXW10P1, HREP, SM25H2" ENSG00000241322 "F-box and WD repeat domain containing 10B" O95170 17 15565483-15619704 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 8.3;testis: 12.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 13.3;Club cells: 13.4;Early spermatids: 27.3;Ionocytes: 25.8;Late spermatids: 13.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 11.3" "Stomach - Gastric mucous cells, Testis - Early spermatids" "HPA013332, HPA047457" Approved Nucleoplasm,Nucleoli NA NA "Cluster 21: Testis - Unknown function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Respiratory epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA013332: AB_1848471, HPA047457: " "unprognostic (2.25e-1)" "unprognostic (2.78e-1)" "unprognostic (7.03e-2)" "unprognostic (3.95e-2)" "unprognostic (1.15e-2)" "unprognostic (1.90e-2)" "unprognostic (1.45e-2)" "unprognostic (5.93e-2)" "unprognostic (5.04e-1)" "unprognostic (1.44e-1)" "unprognostic (1.17e-1)" "unprognostic (3.38e-1)" "unprognostic (9.31e-8)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (5.49e-2)" "unprognostic (1.86e-1)" FMN1 "DKFZP686C2281, FLJ45135, FMN, LD, MGC125288, MGC125289" ENSG00000248905 "Formin 1" Q68DA7 15 32765544-33194714 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 111.5;Cone photoreceptor cells: 186.9;Excitatory neurons: 425.1;Inhibitory neurons: 327.0;Rod photoreceptor cells: 105.9" "Cancer enriched" "Detected in many" 9 "melanoma: 14.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 5 "skin cancer: 45.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005465, HPA046786" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 39: Retina & Testis - Cilium" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 8: Neurons - Neuronal signaling" Nucleoplasm Cytosol "HPA005465: AB_1859515, HPA046786: AB_10963545" "unprognostic (1.57e-1)" "unprognostic (5.92e-3)" "unprognostic (1.96e-1)" "unprognostic (2.10e-3)" "unprognostic (3.67e-2)" "unprognostic (3.00e-2)" "unprognostic (1.56e-2)" "unprognostic (2.84e-2)" "unprognostic (3.44e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-3)" "unprognostic (3.53e-1)" "unprognostic (4.89e-2)" "unprognostic (2.89e-2)" "unprognostic (3.73e-1)" "unprognostic (4.32e-1)" "unprognostic (7.61e-2)" FOXA3 HNF3G ENSG00000170608 "Forkhead box A3" P55318 19 45863989-45873797 "Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "intestine: 17.0;liver: 62.6;pancreas: 46.7;stomach 1: 35.9" "Group enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 136.8;Intestinal goblet cells: 248.6" "Group enriched" "Detected in many" 5 "colorectal cancer: 19.9;liver cancer: 26.4;pancreatic cancer: 20.7;stomach cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 12.6;colorectal cancer: 12.1;Gastric cancer: 15.9" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB015154, HPA054034" Uncertain Approved Nucleoplasm NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 1 Nucleoplasm "CAB015154: AB_647545, HPA054034: AB_2682349" "unprognostic (2.88e-1)" "unprognostic (6.95e-2)" "unprognostic (2.37e-1)" "unprognostic (2.34e-1)" "unprognostic (1.07e-1)" "unprognostic (2.27e-1)" "unprognostic (2.39e-2)" "unprognostic (1.42e-1)" "unprognostic (6.87e-3)" "unprognostic (1.55e-1)" "unprognostic (6.42e-2)" "unprognostic (1.17e-2)" "unprognostic (2.57e-2)" "unprognostic (1.91e-2)" "unprognostic (3.55e-1)" "unprognostic (3.75e-1)" "unprognostic (2.11e-1)" FOXH1 FAST1 ENSG00000160973 "Forkhead box H1" O75593 8 144473412-144475849 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;retina: 2.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 3.0;Gastric mucus-secreting cells: 1.2;Paneth cells: 3.1;Spermatogonia: 1.6" "Cancer enriched" "Detected in some" 26 "testis cancer: 23.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 6.4" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 34: Testis cancer - Unknown function" "Cluster 1: Erythroid cells - Oxygen transport" 48 "unprognostic (1.62e-1)" "unprognostic (8.26e-2)" "unprognostic (4.70e-2)" "unprognostic (2.23e-2)" "unprognostic (2.10e-1)" "unprognostic (1.65e-1)" "unprognostic (1.09e-2)" "unprognostic (3.43e-1)" "unprognostic (4.57e-2)" "unprognostic (6.20e-2)" "unprognostic (3.99e-1)" "unprognostic (1.52e-1)" "unprognostic (2.65e-8)" "unprognostic (1.03e-1)" "unprognostic (3.39e-2)" "unprognostic (3.99e-1)" "unprognostic (9.35e-3)" FOXQ1 HFH1 ENSG00000164379 "Forkhead box Q1" Q9C009 6 1312098-1314758 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 104.5;urinary bladder: 51.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.3;Basal squamous epithelial cells: 55.8;Club cells: 81.4;Gastric mucus-secreting cells: 200.4;Mucus glandular cells: 81.9;Salivary duct cells: 142.9;Squamous epithelial cells: 67.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 53.8" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA059700, CAB080326" Supported Nucleoplasm Yes NA "Cluster 48: Stomach - Proteolysis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 12: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB080326: , HPA059700: AB_2684107" "unprognostic (2.04e-3)" "unprognostic (3.44e-1)" "unprognostic (1.10e-1)" "unprognostic (7.18e-2)" "unprognostic (1.50e-3)" "unprognostic (2.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.15e-3)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.68e-4)" "unprognostic (1.49e-2)" "unprognostic (3.16e-3)" "unprognostic (2.82e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-2)" FUT2 "SE, Se2, SEC2, sej" ENSG00000176920 "Fucosyltransferase 2" Q10981 19 48695971-48705951 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.2;salivary gland: 64.3;stomach 1: 28.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.2;Gastric mucus-secreting cells: 69.0;Ionocytes: 145.1;Mucus glandular cells: 141.4;Proximal enterocytes: 187.9;Salivary duct cells: 110.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.9;Gastric cancer: 18.6" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Region enhanced" "Detected in some" "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA014402 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" 3 "Plasma membrane" Cytosol "HPA014402: AB_1849194" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (2.80e-3)" "unprognostic (4.63e-3)" "unprognostic (2.63e-1)" "prognostic favorable (5.83e-4)" "unprognostic (6.30e-3)" "unprognostic (6.55e-3)" "unprognostic (1.58e-1)" "unprognostic (8.44e-2)" "unprognostic (7.89e-2)" "unprognostic (5.11e-1)" "unprognostic (4.04e-2)" "unprognostic (6.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115823-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1749.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 612.8;Distal enterocytes: 2942.0;Intestinal goblet cells: 871.0;Paneth cells: 1297.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1961.9" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "spinal cord: 5.1" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Transport NA NA "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" 1 Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" "unprognostic (2.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.37e-3)" "unprognostic (3.31e-3)" "unprognostic (6.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.15e-6)" "unprognostic (4.17e-2)" "unprognostic (2.08e-1)" "unprognostic (5.06e-2)" "unprognostic (7.69e-3)" GALE SDR1E1 ENSG00000117308 UDP-galactose-4-epimerase Q14376 1 23795599-23800781 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 119.2" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 250.6;Intestinal goblet cells: 141.4;Ionocytes: 140.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070023 Approved "Golgi apparatus,Cytosol" NA NA 16000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 16: Intestinal goblet cells - Mucin production" "Golgi apparatus, Cytosol" "HPA070023: " "unprognostic (1.65e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (1.41e-2)" "unprognostic (3.03e-3)" "unprognostic (1.17e-2)" "unprognostic (3.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.59e-1)" "unprognostic (2.65e-1)" "unprognostic (1.56e-2)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (7.51e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.68e-4)" "unprognostic (1.41e-2)" GALNT3 "GalNAc-T3, HFTC, HHS" ENSG00000115339 "Polypeptide N-acetylgalactosaminyltransferase 3" Q14435 2 165747588-165794659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 75.3" "Cell type enhanced" "Detected in many" "Early spermatids: 172.5;Intestinal goblet cells: 140.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 50.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007613 Enhanced Supported "Golgi apparatus" NA NA 440000 "Cluster 32: Basophils - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Golgi apparatus" "HPA007613: AB_1078941" "unprognostic (1.95e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.16e-3)" "unprognostic (2.78e-1)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (4.13e-2)" "unprognostic (4.47e-2)" "unprognostic (2.74e-1)" "unprognostic (6.44e-2)" "unprognostic (3.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.79e-2)" "unprognostic (3.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-1)" GALNT4 GalNAc-T4 ENSG00000257594 "Polypeptide N-acetylgalactosaminyltransferase 4" Q8N4A0 12 89519412-89524796 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 30.8" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 10.6;Glandular and luminal cells: 3.2;Mesothelial cells: 2.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076116 Approved "Golgi apparatus" NA NA 520000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 46: Gastric mucus-secreting cells - Digestion" 1 "Golgi apparatus" "HPA076116: AB_2686778" "unprognostic (2.96e-2)" "unprognostic (7.65e-3)" "unprognostic (8.76e-2)" "unprognostic (3.94e-5)" "unprognostic (3.50e-1)" "unprognostic (4.87e-2)" "unprognostic (2.02e-1)" "unprognostic (2.92e-2)" "unprognostic (2.78e-1)" "unprognostic (4.07e-2)" "unprognostic (1.28e-2)" "unprognostic (2.24e-1)" "unprognostic (5.81e-6)" "unprognostic (2.34e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-2)" "unprognostic (2.52e-1)" GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257705-157318491 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.1;lung: 9.9;stomach 1: 12.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 134.2;Alveolar cells type 2: 37.4;Distal enterocytes: 60.2;Intestinal goblet cells: 150.5;Salivary duct cells: 72.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 7 "cerebellum: 8.9;choroid plexus: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 40.6" "Colon - Colon enterocytes, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA 1300000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 5: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" "Golgi apparatus, Cytosol" "Nucleoli, Vesicles" "HPA008963: AB_1078942, HPA009035: AB_1078943" "unprognostic (6.34e-3)" "unprognostic (9.31e-2)" "unprognostic (2.11e-2)" "unprognostic (9.89e-2)" "unprognostic (3.19e-2)" "unprognostic (2.46e-2)" "unprognostic (4.63e-3)" "unprognostic (1.88e-1)" "unprognostic (1.09e-1)" "unprognostic (6.93e-2)" "unprognostic (4.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (6.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (9.48e-3)" GALNT6 GalNAc-T6 ENSG00000139629 "Polypeptide N-acetylgalactosaminyltransferase 6" Q8NCL4 12 51351247-51392867 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.0;stomach 1: 60.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.0;Gastric mucus-secreting cells: 116.1;granulocytes: 95.6;Oligodendrocytes: 53.6;Serous glandular cells: 100.2" "Cancer enhanced" "Detected in many" "breast cancer: 31.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 29.2" "Group enriched" "Detected in all" 4 "granulocytes: 29.2;monocytes: 9.8;NK-cells: 15.7" "Cancer enhanced" "Detected in many" "breast cancer: 56.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011762, HPA017086" Enhanced Approved "Nucleoplasm,Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 4800000 "Cluster 45: Eosinophils - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 2 "Nucleoplasm, Golgi apparatus" "HPA011762: AB_1849450, HPA017086: AB_1849452" "unprognostic (2.03e-1)" "unprognostic (6.65e-2)" "unprognostic (2.26e-2)" "prognostic favorable (9.85e-4)" "unprognostic (1.35e-2)" "unprognostic (1.18e-1)" "unprognostic (7.15e-3)" "unprognostic (2.05e-1)" "unprognostic (2.27e-2)" "prognostic favorable (5.40e-4)" "unprognostic (1.88e-2)" "unprognostic (5.25e-2)" "unprognostic (7.13e-4)" "unprognostic (5.65e-3)" "unprognostic (3.18e-1)" "unprognostic (2.16e-2)" "unprognostic (1.18e-2)" GCNT3 "C2/4GnT, C2GnT-M, C2GnT2" ENSG00000140297 "Glucosaminyl (N-acetyl) transferase 3, mucin type" O95395 15 59594875-59640239 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 73.0;intestine: 138.1;salivary gland: 54.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 105.0;Distal enterocytes: 215.7;Ductal cells: 97.2;Glandular and luminal cells: 76.4;Oocytes: 61.0;Proximal enterocytes: 86.0" "Group enriched" "Detected in many" 4 "colorectal cancer: 16.4;pancreatic cancer: 29.8;stomach cancer: 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 52.0;pancreatic cancer: 51.3" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011154 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Golgi apparatus" Vesicles "HPA011154: AB_1078961" "unprognostic (5.09e-2)" "unprognostic (2.39e-1)" "unprognostic (5.92e-2)" "prognostic favorable (1.78e-4)" "unprognostic (3.99e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (6.49e-5)" "unprognostic (1.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.34e-1)" "unprognostic (1.64e-2)" "unprognostic (1.63e-1)" "unprognostic (4.02e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-2)" "unprognostic (4.65e-2)" "unprognostic (2.43e-1)" GDA "CYPIN, GAH" ENSG00000119125 "Guanine deaminase" Q9Y2T3 9 72114595-72257193 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 71.1;intestine: 92.1;kidney: 41.4;liver: 58.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.6;Glandular and luminal cells: 132.5;Proximal enterocytes: 289.3;Proximal tubular cells: 80.8" "Cancer enhanced" "Detected in many" "renal cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid - Parafollicular cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "amygdala: 50.6;basal ganglia: 42.2;cerebral cortex: 84.8;hippocampal formation: 98.5;olfactory bulb: 26.5" "HPA019352, HPA024099, HPA030387" Enhanced Approved Nucleoplasm No NA 1500000 "Cluster 25: Small intestine - Absorption" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" 1 Nucleoplasm "HPA019352: AB_1855593, HPA024099: AB_1855594, HPA030387: AB_10602351" "unprognostic (2.64e-2)" "unprognostic (7.10e-2)" "unprognostic (2.83e-2)" "unprognostic (2.92e-1)" "unprognostic (4.35e-2)" "unprognostic (8.45e-2)" "unprognostic (2.00e-1)" "unprognostic (5.60e-2)" "unprognostic (3.26e-1)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (5.56e-2)" "prognostic favorable (2.66e-5)" "unprognostic (2.23e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (8.30e-4)" GDPD2 "FLJ20207, GDE3, OBDPF" ENSG00000130055 "Glycerophosphodiester phosphodiesterase domain containing 2" Q9HCC8 X 70423031-70433390 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 14.7;intestine: 20.2;lymphoid tissue: 57.7;skin 1: 46.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 38.3;Distal enterocytes: 31.4;Muller glia cells: 28.0;Proximal enterocytes: 94.9" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 6.2" "Colon - Colon enterocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Skin - Cornification" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "unprognostic (1.53e-3)" "unprognostic (5.79e-2)" "unprognostic (5.37e-2)" "unprognostic (5.00e-7)" "unprognostic (3.15e-3)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" "unprognostic (8.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.41e-2)" "unprognostic (5.52e-2)" "unprognostic (2.22e-1)" "unprognostic (8.91e-2)" GIPR ENSG00000010310 "Gastric inhibitory polypeptide receptor" P48546 19 45668221-45683722 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 22.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 30.8;Enteroendocrine cells: 17.7;Gastric mucus-secreting cells: 34.2;Rod photoreceptor cells: 18.5" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 4.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB022710, HPA068054" Uncertain Uncertain Vesicles NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" 2 Vesicles "CAB022710: , HPA068054: " "unprognostic (2.40e-2)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (3.70e-4)" "unprognostic (1.82e-2)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.85e-3)" "unprognostic (2.78e-1)" "unprognostic (1.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-2)" "unprognostic (2.59e-2)" GJB3 "CX31, DFNA2, EKV" ENSG00000188910 "Gap junction protein beta 3" O75712 1 34781214-34786369 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 75.6;skin 1: 140.5" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 98.9;Basal respiratory cells: 37.5;Basal squamous epithelial cells: 43.4;Squamous epithelial cells: 94.4;Suprabasal keratinocytes: 127.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 58.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA074472 Supported "Vesicles,Cell Junctions" NA NA "Cluster 13: Skin - Cornification" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 10 "Vesicles, Cell Junctions" "HPA074472: AB_2686694" "unprognostic (1.34e-3)" "unprognostic (2.30e-1)" "unprognostic (2.84e-2)" "unprognostic (5.22e-3)" "unprognostic (3.82e-2)" "unprognostic (2.00e-2)" "unprognostic (1.21e-4)" "prognostic unfavorable (4.56e-4)" "unprognostic (2.30e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.50e-2)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-2)" "unprognostic (2.46e-2)" GMDS "GMD, SDR3E1" ENSG00000112699 "GDP-mannose 4,6-dehydratase" O60547 6 1623806-2245605 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 103.0;salivary gland: 102.5;stomach 1: 94.6" "Cell type enhanced" "Detected in all" "Excitatory neurons: 201.6;Gastric mucus-secreting cells: 270.6;Intestinal goblet cells: 296.1;Proximal enterocytes: 202.4;Serous glandular cells: 200.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031528 Enhanced NA NA 72000 "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "HPA031528: AB_10601016" "unprognostic (5.94e-2)" "unprognostic (3.92e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.89e-4)" "unprognostic (4.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.10e-3)" "unprognostic (7.15e-2)" "unprognostic (2.29e-1)" "unprognostic (8.02e-2)" "unprognostic (2.38e-1)" "unprognostic (4.41e-1)" "prognostic favorable (5.93e-4)" "unprognostic (2.45e-1)" "unprognostic (2.84e-1)" "unprognostic (6.68e-2)" "unprognostic (1.12e-1)" GOLM1 "bA379P1.3, C9orf155, FLJ23608, GOLPH2, GP73" ENSG00000135052 "Golgi membrane protein 1" Q8NBJ4 9 86026146-86100173 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 386.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 397.1;Gastric mucus-secreting cells: 240.5;Late spermatids: 447.2;Paneth cells: 244.4" "Cancer enhanced" "Detected in all" "prostate cancer: 343.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 2.2;classical monocyte: 3.5;gdT-cell: 3.5;intermediate monocyte: 2.6;neutrophil: 4.3;non-classical monocyte: 4.2;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010638, HPA011929, CAB015341" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" "No annotated function" NA NA 81000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" 45 "Golgi apparatus" "CAB015341: AB_2113334, HPA010638: AB_1849886, HPA011929: AB_1849888" "unprognostic (1.47e-1)" "unprognostic (2.31e-2)" "unprognostic (1.10e-1)" "prognostic favorable (8.14e-5)" "unprognostic (1.97e-1)" "unprognostic (4.40e-3)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.89e-3)" "unprognostic (2.81e-1)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "unprognostic (1.34e-2)" "unprognostic (5.59e-3)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.87e-3)" "unprognostic (1.23e-1)" GPD2 ENSG00000115159 "Glycerol-3-phosphate dehydrogenase 2" P43304 2 156435290-156613735 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 143.4;Late spermatids: 101.0;Oligodendrocyte precursor cells: 139.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.3;eosinophil: 1.7;intermediate monocyte: 1.6;myeloid DC: 2.7;neutrophil: 1.1;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 1.7;monocytes: 3.3" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008012, HPA045506" Enhanced Supported Mitochondria "Intracellular and membrane" Enzyme NA NA 620000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 79: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 76: Oligodendrocyte precursor - Unknown function" Mitochondria "HPA008012: AB_1079013, HPA045506: AB_2679355" "unprognostic (1.30e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (4.79e-3)" "unprognostic (3.25e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (2.60e-3)" "unprognostic (6.67e-2)" "unprognostic (6.02e-3)" "unprognostic (1.73e-1)" "unprognostic (1.89e-1)" "unprognostic (2.41e-1)" "unprognostic (1.01e-2)" GPR35 ENSG00000178623 "G protein-coupled receptor 35" Q9HC97 2 240605430-240633159 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 45.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 74.8;Intestinal goblet cells: 27.5;Langerhans cells: 42.6;monocytes: 55.1;Paneth cells: 31.5;Proximal enterocytes: 90.4" "Group enriched" "Detected in many" 4 "colorectal cancer: 20.7;pancreatic cancer: 6.9;stomach cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "classical monocyte: 31.0;eosinophil: 32.6;intermediate monocyte: 44.7;myeloid DC: 27.6;non-classical monocyte: 12.3" "Group enriched" "Detected in many" 16 "dendritic cells: 27.6;granulocytes: 32.6;monocytes: 44.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 32.8;colorectal cancer: 59.8;Gastric cancer: 38.3" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "unprognostic (1.05e-1)" "unprognostic (2.89e-2)" "unprognostic (4.35e-2)" "unprognostic (1.53e-1)" "unprognostic (5.99e-2)" "unprognostic (3.94e-3)" "unprognostic (2.71e-2)" "prognostic unfavorable (5.86e-4)" "unprognostic (2.01e-1)" "unprognostic (2.07e-1)" "unprognostic (7.98e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (2.59e-5)" "unprognostic (7.03e-3)" "unprognostic (1.30e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-3)" GPX2 GSHPX-GI ENSG00000176153 "Glutathione peroxidase 2" P18283 14 64939152-64942746 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 476.9;intestine: 435.3;liver: 561.9;stomach 1: 357.0;urinary bladder: 333.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 400.6;Distal enterocytes: 428.1;Gastric mucus-secreting cells: 906.7;Hepatocytes: 882.8;Paneth cells: 421.6;Squamous epithelial cells: 351.1;Undifferentiated cells: 518.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 493.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1245.0" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Region enriched" "Detected in single" 5 "pons and medulla: 4.1" "Low region specificity" "Detected in many" "HPA003545, HPA075070" Enhanced Supported "Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA 82000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" Cytosol "Cytokinetic bridge, Mitotic spindle" "HPA003545: AB_10962695, HPA075070: " "unprognostic (3.54e-1)" "unprognostic (1.08e-2)" "unprognostic (1.51e-1)" "unprognostic (1.90e-3)" "unprognostic (4.75e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.96e-2)" "unprognostic (2.93e-2)" "unprognostic (7.87e-2)" "unprognostic (1.54e-2)" "unprognostic (8.45e-2)" "unprognostic (1.44e-1)" "unprognostic (2.77e-2)" "unprognostic (4.39e-2)" "unprognostic (3.39e-2)" "unprognostic (6.66e-4)" "unprognostic (1.73e-2)" GSDMB "GSDML, PRO2521" ENSG00000073605 "Gasdermin B" Q8TAX9 17 39904595-39919854 "Predicted intracellular proteins, Transporters" "Cytolysis, Necrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.1;liver: 51.6;stomach 1: 46.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.3;Gastric mucus-secreting cells: 60.1;Intestinal goblet cells: 43.6;Paneth cells: 39.4;Proximal enterocytes: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "CAB013681, HPA023925, HPA052407" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm Cytosol "CAB013681: , HPA023925: AB_1850383, HPA052407: AB_2681819" "unprognostic (5.78e-2)" "prognostic favorable (3.41e-5)" "unprognostic (1.27e-1)" "unprognostic (5.70e-2)" "unprognostic (6.85e-2)" "unprognostic (2.81e-1)" "unprognostic (1.10e-1)" "unprognostic (6.44e-2)" "unprognostic (3.81e-1)" "unprognostic (8.72e-2)" "unprognostic (2.34e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (5.13e-11)" "unprognostic (1.88e-1)" "unprognostic (1.99e-1)" "unprognostic (8.91e-2)" "prognostic favorable (5.91e-9)" GSR ENSG00000104687 "Glutathione-disulfide reductase" P00390 8 30678066-30727846 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001538, CAB008632, HPA064806" Approved Supported Cytosol NA NA 81000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" Cytosol "CAB008632: AB_1616690, HPA001538: AB_1078986, HPA064806: " "unprognostic (1.23e-1)" "prognostic favorable (3.37e-4)" "prognostic favorable (4.08e-5)" "unprognostic (2.89e-3)" "unprognostic (1.62e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (4.15e-2)" "unprognostic (2.83e-2)" "unprognostic (6.92e-3)" "prognostic favorable (1.80e-4)" "unprognostic (2.31e-3)" "unprognostic (2.26e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" HNF4A "HNF4, MODY, MODY1, NR2A1, TCF14" ENSG00000101076 "Hepatocyte nuclear factor 4 alpha" P41235 20 44355699-44432845 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 99.3;kidney: 44.1;liver: 114.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 163.1;Enteroendocrine cells: 66.0;Hepatocytes: 174.9;Intestinal goblet cells: 67.3;Paneth cells: 89.0;Proximal enterocytes: 137.0;Proximal tubular cells: 161.2;Undifferentiated cells: 78.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 48.2;liver cancer: 38.4" "Region enriched" "Detected in all" 10 "choroid plexus: 32.2" "Immune cell enhanced" "Detected in single" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "Bile duct cancer: 19.2;colorectal cancer: 57.4;Gastric cancer: 33.3;liver cancer: 41.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004712, CAB019417" Enhanced Supported Nucleoplasm NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 4 Nucleoplasm "CAB019417: AB_2295208, HPA004712: AB_1079075" "unprognostic (2.47e-1)" "unprognostic (3.08e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-1)" "unprognostic (8.54e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-2)" "unprognostic (4.79e-3)" "unprognostic (2.59e-2)" "unprognostic (3.77e-2)" "unprognostic (2.45e-2)" "unprognostic (1.05e-1)" "unprognostic (2.75e-2)" "unprognostic (8.40e-3)" "unprognostic (2.12e-1)" "unprognostic (2.70e-2)" HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 111.4" "Cell type enhanced" "Detected in some" "Astrocytes: 37.8;Distal enterocytes: 51.0;Enteroendocrine cells: 27.2;Intestinal goblet cells: 37.6;Oligodendrocyte precursor cells: 24.5;Paneth cells: 48.0;Proximal enterocytes: 135.8;Undifferentiated cells: 29.0" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.5;liver cancer: 2.8;pancreatic cancer: 4.0;renal cancer: 4.6;stomach cancer: 10.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Small intestine - Absorption" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: AB_1850822, HPA010610: AB_2668318" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (9.44e-2)" "unprognostic (5.60e-2)" "unprognostic (4.65e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.92e-1)" "unprognostic (8.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.83e-2)" "unprognostic (6.93e-3)" "unprognostic (1.67e-2)" "unprognostic (2.11e-1)" "unprognostic (4.22e-2)" "unprognostic (2.47e-2)" HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Differentiation, Host-virus interaction" "Developmental protein, Oxidoreductase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 263.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 1 Cytosol "HPA006417: AB_1079091, HPA024321: AB_1851288" "unprognostic (8.05e-3)" "unprognostic (2.13e-1)" "unprognostic (9.31e-2)" "unprognostic (3.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.79e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.20e-3)" "unprognostic (1.05e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.20e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" HYAL1 "HYAL-1, LUCA1" ENSG00000114378 "Hyaluronidase 1" Q12794 3 50299890-50312381 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 196.6;lymphoid tissue: 92.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 25.1;Hepatocytes: 119.5;Proximal tubular cells: 49.9" "Cancer enhanced" "Detected in all" "liver cancer: 37.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.3" "Cancer enhanced" "Detected in many" "liver cancer: 17.4" "Colon - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Endothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002112 Uncertain "Secreted to blood" Enzyme NA NA 590000 "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 18: Liver cancer - Metabolism" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "HPA002112: AB_1857412" "unprognostic (1.39e-1)" "unprognostic (8.68e-2)" "prognostic favorable (2.07e-4)" "unprognostic (5.23e-2)" "unprognostic (3.18e-1)" "unprognostic (8.71e-2)" "unprognostic (9.35e-2)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (1.31e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-1)" "prognostic favorable (1.56e-11)" "unprognostic (4.51e-2)" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.90e-2)" IGF2BP2 "IMP-2, p62" ENSG00000073792 "Insulin like growth factor 2 mRNA binding protein 2" Q9Y6M1 3 185643130-185825042 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 115.3;Late spermatids: 104.2;Rod photoreceptor cells: 175.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017126, HPA035145" Enhanced Enhanced Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 39: Retina & Testis - Cilium" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 50: Connective tissue cells - ECM organization" 2 Cytosol "CAB017126: , HPA035145: AB_2674491" "unprognostic (7.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.12e-5)" "unprognostic (2.46e-3)" "unprognostic (8.25e-3)" "unprognostic (4.17e-1)" "unprognostic (3.45e-2)" "prognostic unfavorable (7.37e-5)" "unprognostic (1.77e-1)" "unprognostic (1.25e-1)" "unprognostic (9.45e-2)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (4.94e-3)" IL17REL FLJ41993 ENSG00000188263 "Interleukin 17 receptor E like" 22 49991811-50012765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 4.2;stomach 1: 1.8" "Group enriched" "Detected in some" 26 "Gastric mucus-secreting cells: 13.6;Oocytes: 4.4" "Cancer enhanced" "Detected in some" "stomach cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" HPA045546 Supported NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 46: Gastric mucus-secreting cells - Digestion" "HPA045546: AB_10963836" "unprognostic (3.33e-1)" "unprognostic (1.98e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-1)" "unprognostic (6.33e-2)" "unprognostic (4.65e-4)" "unprognostic (2.72e-2)" "unprognostic (1.01e-3)" "unprognostic (4.45e-2)" "unprognostic (1.52e-1)" "unprognostic (3.94e-1)" "unprognostic (3.02e-2)" "unprognostic (4.60e-4)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (6.31e-3)" "unprognostic (8.31e-2)" IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113099315-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1898.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 324.5;Hofbauer cells: 399.9;Langerhans cells: 377.6;Squamous epithelial cells: 526.1;Suprabasal keratinocytes: 1054.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "classical monocyte: 69.8;myeloid DC: 66.9;neutrophil: 257.2" "Group enriched" "Detected in many" 738 "dendritic cells: 66.9;granulocytes: 257.2;monocytes: 69.8" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 164.8" "Heart muscle - Neutrophils, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "HPA001482, CAB009633, CAB080340" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" "No annotated function" NA NA 291000 45000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "Nucleoplasm, Cytosol" Centrosome "CAB009633: AB_2125576, CAB080340: , HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" IL22RA1 "CRF2-9, IL22R" ENSG00000142677 "Interleukin 22 receptor subunit alpha 1" Q8N6P7 1 24119771-24143140 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 193.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 19.4;Exocrine glandular cells: 7.2;Intestinal goblet cells: 15.7;Proximal enterocytes: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.2" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 35: Non-specific - DNA binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 2 "unprognostic (1.68e-3)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-3)" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-3)" "unprognostic (1.12e-1)" "unprognostic (7.63e-2)" "unprognostic (1.72e-3)" "unprognostic (2.28e-1)" "unprognostic (4.78e-3)" "unprognostic (1.05e-2)" "unprognostic (2.57e-1)" "unprognostic (2.63e-1)" "unprognostic (1.64e-2)" INAVA "C1orf106, FLJ10901" ENSG00000163362 "Innate immunity activator" Q3KP66 1 200891048-200915742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.9;intestine: 53.9;skin 1: 45.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 109.7;Gastric mucus-secreting cells: 62.5;Intestinal goblet cells: 99.7;Paneth cells: 72.1;Proximal enterocytes: 150.4;Suprabasal keratinocytes: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA027499, HPA027511, HPA079622" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 4 Nucleoplasm "Nuclear bodies" "HPA027499: AB_10599708, HPA027511: AB_10600334, HPA079622: " "unprognostic (3.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.78e-5)" "unprognostic (4.56e-2)" "unprognostic (2.18e-1)" "unprognostic (2.74e-2)" "unprognostic (6.62e-3)" "unprognostic (2.84e-2)" "unprognostic (9.38e-2)" "unprognostic (2.52e-2)" "unprognostic (2.81e-1)" "unprognostic (3.23e-3)" "unprognostic (1.67e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.73e-2)" ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 66.2;skeletal muscle: 77.1;tongue: 62.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 82.9;Alveolar cells type 2: 105.6;Basal respiratory cells: 118.7;Collecting duct cells: 72.0;Ductal cells: 59.4;Exocrine glandular cells: 104.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" ITPKA "IP3-3KA, IP3KA" ENSG00000137825 "Inositol-trisphosphate 3-kinase A" P23677 15 41493393-41503551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.5;intestine: 17.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 59.0;Early spermatids: 43.8;Excitatory neurons: 22.9;Gastric mucus-secreting cells: 30.1;Late spermatids: 165.8;Proximal enterocytes: 33.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 11 "T-cells: 1.4" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "amygdala: 11.2;basal ganglia: 44.1;cerebral cortex: 33.5;hippocampal formation: 29.2" HPA040454 Enhanced Approved Approved "Vesicles,Plasma membrane" No No "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" Vesicles "Plasma membrane" "HPA040454: AB_10672897" "unprognostic (5.91e-2)" "unprognostic (2.16e-3)" "unprognostic (4.19e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.77e-4)" "unprognostic (2.25e-2)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.76e-9)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-3)" "unprognostic (2.10e-2)" ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 80.4;Gastric mucus-secreting cells: 115.0;Late spermatids: 231.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003915, HPA064704" Approved Uncertain Vesicles No Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 11: Late spermatids - Unknown function" 2 Vesicles "HPA003915: AB_1851845, HPA064704: " "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.08e-2)" "unprognostic (6.14e-2)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-3)" "unprognostic (1.88e-1)" "unprognostic (6.44e-3)" "unprognostic (5.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.89e-2)" "unprognostic (2.43e-2)" JUP "CTNNG, DP3, DPIII, PDGB, PG, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 925.5;skin 1: 902.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 376.1;Squamous epithelial cells: 354.3;Suprabasal keratinocytes: 852.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.2;eosinophil: 28.8;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.6;naive B-cell: 11.7;non-classical monocyte: 44.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 14 "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" KCNK1 "DPK, K2p1.1, TWIK-1" ENSG00000135750 "Potassium two pore domain channel subfamily K member 1" O00180 1 233614106-233672514 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.9;choroid plexus: 72.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 152.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 70 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 70 "dendritic cells: 6.9" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 160.5" "HPA016049, CAB022588" Approved Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 65: Cerebellum - Nervous system development" "Cluster 5: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" 8 Vesicles "CAB022588: , HPA016049: AB_1855571" "unprognostic (7.06e-3)" "unprognostic (1.76e-1)" "unprognostic (4.64e-2)" "unprognostic (7.46e-2)" "unprognostic (9.15e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.84e-4)" "unprognostic (4.32e-2)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (7.29e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" KCNK10 "K2p10.1, PPP1R97, TREK-2, TREK2" ENSG00000100433 "Potassium two pore domain channel subfamily K member 10" P57789 14 88180103-88326907 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;intestine: 4.9;stomach 1: 2.5" "Cell type enhanced" "Detected in some" "dendritic cells: 51.3;Excitatory neurons: 42.4;Inhibitory neurons: 16.3;Oligodendrocyte precursor cells: 35.4;Oligodendrocytes: 11.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 62 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in single" 100 "dendritic cells: 10.0" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.5" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030462 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "HPA030462: AB_10601919" "unprognostic (9.52e-3)" "unprognostic (1.17e-1)" "unprognostic (1.94e-2)" "unprognostic (1.08e-1)" "unprognostic (8.20e-2)" "unprognostic (1.45e-1)" "unprognostic (1.18e-1)" "unprognostic (2.25e-1)" "unprognostic (4.58e-1)" "unprognostic (1.23e-2)" "unprognostic (2.70e-1)" "unprognostic (2.45e-1)" "unprognostic (6.97e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-1)" "unprognostic (4.26e-3)" KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43780976 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 122.7" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 223.3;Syncytiotrophoblasts: 783.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 7 "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 122.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "KLF transcription factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 235.2;skin 1: 228.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 854.1;Early spermatids: 559.9;Glandular and luminal cells: 652.2;Squamous epithelial cells: 998.2;Suprabasal keratinocytes: 678.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 20 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 30.7" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 6 Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: AB_10673267" "unprognostic (7.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.03e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (3.97e-2)" "unprognostic (5.82e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (4.43e-2)" "unprognostic (1.42e-3)" "unprognostic (3.56e-3)" "unprognostic (3.98e-1)" "unprognostic (5.09e-2)" "unprognostic (1.54e-2)" KPNA7 IPOA8 ENSG00000185467 "Karyopherin subunit alpha 7" A9QM74 7 99173572-99250075 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "ovary: 3.2;stomach 1: 3.5" "Cell type enriched" "Detected in some" 53 "Oocytes: 738.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.2" "Breast - Breast glandular cells, Breast - Breast glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA031395 Uncertain NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 44: Oocytes - Unknown function" "HPA031395: AB_10601584" "unprognostic (7.38e-2)" "unprognostic (7.99e-2)" "unprognostic (2.23e-1)" "unprognostic (8.44e-2)" "unprognostic (8.37e-2)" "unprognostic (9.35e-2)" "unprognostic (9.77e-2)" "unprognostic (2.25e-2)" "unprognostic (2.30e-1)" "unprognostic (3.23e-1)" "unprognostic (7.94e-3)" "unprognostic (5.89e-2)" "unprognostic (2.28e-13)" "unprognostic (2.21e-2)" "unprognostic (1.23e-1)" "unprognostic (3.54e-2)" KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 864.1;salivary gland: 786.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 6850.6;Club cells: 5440.4;Distal enterocytes: 7654.8;Extravillous trophoblasts: 8032.7;Proximal enterocytes: 8878.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 13.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 4070.4" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 62.5" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 300000000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 65 "Intermediate filaments" "CAB000031: AB_2234418, HPA002465: AB_1079179" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.82e-5)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (3.52e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.35e-2)" KRT20 "CK20, K20, MGC35423" ENSG00000171431 "Keratin 20" P35900 17 40875889-40885242 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 629.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 2017.7;Enteroendocrine cells: 335.6;Intestinal goblet cells: 454.6;Paneth cells: 1576.2;Proximal enterocytes: 1249.8" "Group enriched" "Detected in many" 6 "colorectal cancer: 159.5;stomach cancer: 52.7;urothelial cancer: 99.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 41.5;colorectal cancer: 95.3;liver cancer: 50.6" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000032, HPA024309, HPA024684, HPA027236" Enhanced Supported "Intermediate filaments,Cytosol" NA NA 30000000 "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 32 "Intermediate filaments, Cytosol" "CAB000032: AB_2133718, HPA024309: AB_1852220, HPA024684: AB_1852222, HPA027236: AB_1852224" "unprognostic (3.49e-1)" "unprognostic (3.13e-1)" "unprognostic (1.71e-1)" "unprognostic (6.38e-3)" "unprognostic (5.12e-2)" "unprognostic (2.66e-3)" "prognostic unfavorable (7.05e-4)" "unprognostic (2.63e-2)" "unprognostic (4.87e-3)" "unprognostic (2.37e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (5.71e-2)" "unprognostic (6.30e-2)" "unprognostic (7.27e-2)" KRT8 "CARD2, CK-8, CK8, CYK8, K2C8, K8, KO" ENSG00000170421 "Keratin 8" P05787 12 52897187-52949954 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1323.0;stomach 1: 793.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 12319.1;Ductal cells: 5203.4;Extravillous trophoblasts: 6075.3;Paneth cells: 8520.4;Proximal enterocytes: 7547.1;Syncytiotrophoblasts: 5966.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 64.6" "CAB000131, CAB001696, HPA049866" Enhanced Supported "Intermediate filaments" NA NA 1700000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 20 "Intermediate filaments" "CAB000131: AB_2281144, CAB001696: , HPA049866: AB_2680923" "unprognostic (5.72e-2)" "unprognostic (2.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "unprognostic (2.76e-2)" "unprognostic (4.86e-3)" "unprognostic (3.10e-2)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (8.99e-2)" "unprognostic (2.08e-2)" "unprognostic (2.83e-2)" "unprognostic (3.18e-1)" "unprognostic (3.68e-1)" "unprognostic (1.19e-2)" KRTCAP3 KCP3 ENSG00000157992 "Keratinocyte associated protein 3" Q53RY4 2 27442366-27446481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 153.5;Proximal enterocytes: 170.2;Undifferentiated cells: 179.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "MAIT T-cell: 6.8;memory B-cell: 4.5;memory CD4 T-cell: 5.7;memory CD8 T-cell: 2.6;naive B-cell: 6.5;naive CD4 T-cell: 6.6;naive CD8 T-cell: 2.7;T-reg: 4.4" "Group enriched" "Detected in many" 13 "B-cells: 6.5;T-cells: 6.8" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA047136, HPA060203" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Nucleoplasm, Cytosol" "HPA047136: AB_2679949, HPA060203: AB_2684221" "prognostic favorable (2.67e-5)" "unprognostic (5.93e-2)" "unprognostic (5.03e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-1)" "unprognostic (7.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (9.43e-2)" "unprognostic (1.60e-2)" "unprognostic (1.44e-2)" "unprognostic (4.63e-2)" "unprognostic (1.04e-1)" "unprognostic (3.73e-3)" "unprognostic (3.79e-2)" "unprognostic (8.21e-2)" "unprognostic (9.42e-3)" LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 352.0;skin 1: 208.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 151.4;Distal enterocytes: 143.5;Ductal cells: 156.4;Oocytes: 146.3;Proximal enterocytes: 232.2;Squamous epithelial cells: 213.2;Suprabasal keratinocytes: 354.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 257.9" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Actin filaments" "HPA007256: AB_1852681, HPA028732: AB_10602916" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.82e-1)" "unprognostic (7.55e-3)" "unprognostic (4.66e-2)" "unprognostic (7.41e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (9.11e-2)" "unprognostic (2.31e-2)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 71.3;urinary bladder: 70.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 215.0;Basal respiratory cells: 405.4;Ductal cells: 165.9;Gastric mucus-secreting cells: 175.7;Ionocytes: 178.6;Salivary duct cells: 225.6" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 41.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 438.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" "Cell adhesion" NA NA 20000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" LGALS9 LGALS9A ENSG00000168961 "Galectin 9" O00182 17 27629798-27649560 "Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 95.8;stomach 1: 85.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 188.2;Gastric mucus-secreting cells: 163.9;Hofbauer cells: 314.6;Intestinal goblet cells: 172.3;Kupffer cells: 213.0;Macrophages: 160.4;monocytes: 222.0;Paneth cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 66.9" "Lung - Macrophages, Stomach - Gastric mucous cells" "HPA046876, HPA047218, CAB080347" Approved Supported Cytosol "Secreted to blood" Immunity NA NA 448000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" Cytosol "CAB080347: , HPA046876: AB_2679852, HPA047218: AB_2679988" "unprognostic (2.62e-2)" "prognostic favorable (2.35e-5)" "unprognostic (1.16e-2)" "unprognostic (3.57e-1)" "unprognostic (2.01e-1)" "unprognostic (2.46e-3)" "unprognostic (1.58e-2)" "unprognostic (8.60e-2)" "unprognostic (4.79e-1)" "unprognostic (1.80e-1)" "unprognostic (8.13e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (4.76e-2)" "unprognostic (3.02e-2)" "unprognostic (2.23e-2)" "unprognostic (2.24e-3)" LGALS9B ENSG00000170298 "Galectin 9B" Q3B8N2 17 20449395-20467539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 15.0;intestine: 10.7;stomach 1: 30.0" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 90.8;Intestinal goblet cells: 51.1;NK-cells: 21.9;Paneth cells: 44.4" "Cancer enhanced" "Detected in some" "stomach cancer: 1.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 17 "NK-cell: 13.3" "Lineage enriched" "Detected in single" 17 "NK-cells: 13.3" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.3;pancreatic cancer: 2.4" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "HPA046876, HPA047218" Approved Uncertain Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 7 Cytosol "HPA046876: AB_2679852, HPA047218: AB_2679988" "unprognostic (4.69e-2)" "unprognostic (1.11e-2)" "unprognostic (2.67e-2)" "unprognostic (4.05e-1)" "unprognostic (8.62e-2)" "unprognostic (1.94e-1)" "unprognostic (3.93e-3)" "unprognostic (2.72e-1)" "unprognostic (2.26e-2)" "unprognostic (6.85e-2)" "unprognostic (1.32e-2)" "unprognostic (3.20e-1)" "unprognostic (3.79e-2)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (5.27e-2)" "unprognostic (1.05e-1)" LGALS9C ENSG00000171916 "Galectin 9C" Q6DKI2 17 18476737-18494945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 10.0;intestine: 9.1;stomach 1: 11.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 23.3;Gastric mucus-secreting cells: 167.4;Intestinal goblet cells: 58.4;Paneth cells: 45.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "neutrophil: 1.9;NK-cell: 5.5" "Group enriched" "Detected in many" 6 "granulocytes: 1.9;NK-cells: 5.5" "Not detected" "Not detected" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "HPA046876, HPA047218" Approved Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 23 Cytosol "HPA046876: AB_2679852, HPA047218: AB_2679988" "unprognostic (4.47e-2)" "unprognostic (1.43e-3)" "unprognostic (3.17e-2)" "unprognostic (4.30e-2)" "unprognostic (5.92e-1)" "unprognostic (3.02e-2)" "unprognostic (2.52e-1)" "unprognostic (5.16e-2)" "unprognostic (1.63e-1)" "unprognostic (2.56e-1)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.04e-2)" "unprognostic (5.85e-2)" "unprognostic (4.27e-3)" "unprognostic (9.84e-2)" LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 40.1;neutrophil: 97.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 97.2" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 2 Nucleoplasm Cytosol "CAB019313: , HPA008183: AB_1079252, HPA053882: AB_2682291" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" LIPH "LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B" ENSG00000163898 "Lipase H" Q8WWY8 3 185506262-185552588 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.5;stomach 1: 47.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 152.9;Gastric mucus-secreting cells: 172.1;Granulosa cells: 101.5;Intestinal goblet cells: 159.8;Ionocytes: 397.6;Proximal enterocytes: 138.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 39.7;pancreatic cancer: 33.3" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA049079 Approved "Secreted to blood" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA049079: AB_2680623" "unprognostic (4.50e-3)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (3.38e-1)" "unprognostic (1.01e-1)" "unprognostic (8.59e-2)" "unprognostic (1.44e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (7.88e-2)" "prognostic favorable (9.20e-5)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (4.21e-4)" "unprognostic (1.15e-1)" LMO7 "FBX20, FBXO20, KIAA0858" ENSG00000136153 "LIM domain 7" Q8WWI1 13 75620434-75859870 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 240.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 707.1;Cardiomyocytes: 514.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 13.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 35.2;basal ganglia: 57.1;cerebral cortex: 46.1;hippocampal formation: 59.7" "HPA020923, HPA050184" Enhanced Supported "Actin filaments,Cytosol" NA NA 8200 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mitochondria" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Alveolar cells - Lung function" "Actin filaments" Cytosol "HPA020923: AB_1852963, HPA050184: AB_2681045" "unprognostic (2.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.75e-2)" "unprognostic (1.44e-1)" "unprognostic (1.57e-2)" "unprognostic (1.97e-1)" "unprognostic (1.52e-2)" "unprognostic (3.42e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.14e-1)" "prognostic favorable (7.75e-12)" "unprognostic (2.49e-1)" "unprognostic (2.82e-1)" "unprognostic (1.08e-1)" "unprognostic (8.33e-2)" LPCAT4 "AGPAT7, AYTL3, FLJ10257, LPAAT-eta, LPEAT2, LPLAT10" ENSG00000176454 "Lysophosphatidylcholine acyltransferase 4" Q643R3 15 34358633-34367196 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 96.0;Gastric mucus-secreting cells: 123.2;Paneth cells: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057321 Supported NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA057321: " "unprognostic (2.79e-2)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (4.64e-3)" "unprognostic (1.29e-2)" "unprognostic (2.15e-2)" "prognostic unfavorable (9.99e-4)" "unprognostic (7.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.90e-1)" "unprognostic (1.23e-3)" "unprognostic (1.33e-1)" "unprognostic (9.95e-3)" "unprognostic (1.52e-2)" "unprognostic (1.37e-1)" "unprognostic (1.69e-2)" "unprognostic (3.44e-3)" LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2885296-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 146.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 6 "granulocytes: 32.0;NK-cells: 13.3;T-cells: 12.0" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 209.3;Distal enterocytes: 256.9;Ductal cells: 236.0;Exocrine glandular cells: 243.4;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA 3500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Plasma membrane, Cell Junctions" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" LYPD6B "CT116, LYPD7" ENSG00000150556 "LY6/PLAUR domain containing 6B" Q8NI32 2 149038107-149215262 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 92.5" "Cell type enhanced" "Detected in many" "Early spermatids: 233.7;Gastric mucus-secreting cells: 78.4;Inhibitory neurons: 75.0;Late spermatids: 137.2;Secretory cells: 59.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "basophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049239 Uncertain "Intracellular and membrane" "No annotated function" NA NA "Cluster 32: Basophils - Transcription" "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 21: Early spermatids - Spermatogenesis" "HPA049239: AB_2680688" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (3.12e-3)" "unprognostic (1.64e-1)" "unprognostic (3.37e-1)" "unprognostic (2.01e-2)" "unprognostic (6.27e-2)" "unprognostic (3.64e-2)" "unprognostic (7.95e-3)" "unprognostic (2.59e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-3)" MACIR "C5orf30, FLJ25291" ENSG00000181751 "Macrophage immunometabolism regulator" Q96GV9 5 103258763-103278660 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Inflammatory response, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 69.8;Extravillous trophoblasts: 118.6;Muller glia cells: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 37.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 37.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043434 Uncertain NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 5: Enterocytes - Absorption" 6 "HPA043434: AB_2678480" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (6.59e-3)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.85e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (1.78e-5)" "unprognostic (1.15e-1)" "unprognostic (3.85e-2)" "unprognostic (8.76e-2)" "unprognostic (4.36e-2)" "unprognostic (1.88e-1)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (2.29e-1)" "unprognostic (5.23e-2)" "unprognostic (1.83e-2)" MAL2 ENSG00000147676 "Mal, T cell differentiation protein 2" Q969L2 8 119165034-119245673 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 252.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 390.8;Collecting duct cells: 334.5;Distal enterocytes: 359.9;Squamous epithelial cells: 320.2;Suprabasal keratinocytes: 583.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043831 Uncertain NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 37 "HPA043831: " "prognostic unfavorable (4.57e-6)" "unprognostic (3.12e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (2.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.03e-2)" "unprognostic (7.20e-2)" "unprognostic (5.86e-2)" "unprognostic (2.00e-3)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.09e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.48e-2)" "unprognostic (1.34e-1)" "unprognostic (3.33e-1)" "unprognostic (9.27e-3)" MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 99.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 145.1;Late spermatids: 277.2;Proximal enterocytes: 180.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Region enriched" "Detected in all" 14 "cerebellum: 41.0" "HPA007667, CAB025854" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 17: Breast glandular cells - Lactation" 2 "Nucleoplasm, Nucleoli, Nucleoli rim, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favorable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" MCU "C10orf42, CCDC109A, FLJ46135" ENSG00000156026 "Mitochondrial calcium uniporter" Q8NE86 10 72692143-72887694 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 52.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.2;Gastric mucus-secreting cells: 67.8;Inhibitory neurons: 62.9;Oligodendrocyte precursor cells: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016480 Approved Supported Mitochondria No No 17000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Neurons - Synaptic function" 2 Mitochondria "HPA016480: AB_2071893" "unprognostic (2.42e-2)" "unprognostic (1.58e-2)" "unprognostic (3.01e-2)" "unprognostic (5.37e-2)" "unprognostic (7.84e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (6.06e-5)" "unprognostic (1.23e-1)" "unprognostic (2.28e-1)" "unprognostic (2.33e-1)" "unprognostic (5.12e-3)" "unprognostic (1.73e-1)" "prognostic favorable (5.07e-4)" "unprognostic (4.51e-2)" "unprognostic (3.79e-1)" "unprognostic (2.74e-2)" "unprognostic (2.48e-2)" MGAT4B GnT-Ivb ENSG00000161013 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B" Q9UQ53 5 179797597-179806952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 270.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 209.2;Proximal enterocytes: 212.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 5.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.5" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012804, HPA052134" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA 19000 "Cluster 19: Eosinophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 2 Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA012804: , HPA052134: AB_2681741" "unprognostic (2.01e-2)" "unprognostic (8.68e-3)" "unprognostic (1.40e-1)" "unprognostic (3.83e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (3.61e-3)" "unprognostic (7.57e-3)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (5.13e-2)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "prognostic favorable (5.78e-4)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.42e-1)" MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 191.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 783.4;Intestinal goblet cells: 233.5;Paneth cells: 464.7;Proximal enterocytes: 1059.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 104.4" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 44 "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" MKRN2OS "C3orf83, MKRN2-AS1" ENSG00000225526 "MKRN2 opposite strand" H3BPM6 3 12514934-12561059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 6.9;intestine: 6.9" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 13.4;Paneth cells: 14.6;Proximal enterocytes: 23.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.3" "Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA065586, HPA065753" Uncertain Approved "Golgi apparatus" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" "Golgi apparatus" "HPA065586: AB_2685514, HPA065753: AB_2685553" "unprognostic (2.53e-2)" "unprognostic (1.01e-2)" "unprognostic (3.89e-3)" "unprognostic (2.03e-3)" "unprognostic (3.81e-1)" "unprognostic (8.45e-2)" "unprognostic (2.24e-1)" "unprognostic (2.29e-1)" "unprognostic (5.26e-2)" "unprognostic (3.86e-2)" "unprognostic (1.58e-2)" "unprognostic (4.29e-3)" "unprognostic (2.53e-5)" "unprognostic (1.02e-1)" "unprognostic (2.48e-1)" "unprognostic (8.50e-3)" "unprognostic (3.17e-3)" MLPH "exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a" ENSG00000115648 Melanophilin Q9BV36 2 237485428-237555322 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 131.9;salivary gland: 118.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 257.7;Gastric mucus-secreting cells: 242.9;granulocytes: 187.7;Intestinal goblet cells: 233.1;Mucus glandular cells: 125.5;Prostatic glandular cells: 153.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA014685 Enhanced NA NA "Cluster 68: Non-specific - Protein processing" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 4 "HPA014685: AB_1853997" "unprognostic (3.32e-3)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "prognostic favorable (5.14e-6)" "unprognostic (2.26e-4)" "unprognostic (1.36e-2)" "unprognostic (5.44e-2)" "unprognostic (2.66e-1)" "unprognostic (3.74e-3)" "unprognostic (8.16e-2)" "unprognostic (5.73e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.34e-1)" "unprognostic (9.37e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-3)" MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 51.5;Distal enterocytes: 88.5;Extravillous trophoblasts: 53.6;Proximal enterocytes: 59.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 5: Enterocytes - Absorption" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: AB_2676956" "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favorable (3.08e-4)" MPDU1 "CDGIf, Lec35, PQLC5, SL15, SLC66A5" ENSG00000129255 "Mannose-P-dolichol utilization defect 1" O75352 17 7583529-7592789 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 161.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014845 Uncertain Supported "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "Endoplasmic reticulum" Mitochondria "HPA014845: AB_1854072" "unprognostic (1.96e-1)" "unprognostic (8.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.36e-2)" "unprognostic (5.00e-2)" "unprognostic (5.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.65e-1)" "unprognostic (4.70e-2)" "unprognostic (3.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (2.34e-3)" "unprognostic (9.00e-2)" "unprognostic (2.60e-1)" "unprognostic (2.48e-3)" "unprognostic (2.93e-1)" MRAP2 "bA51G5.2, C6orf117" ENSG00000135324 "Melanocortin 2 receptor accessory protein 2" Q96G30 6 84033772-84090881 "Disease related genes, Human disease related genes, Predicted membrane proteins" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.6;Gastric mucus-secreting cells: 15.3;Inhibitory neurons: 32.0;Oocytes: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.4" "Adipose visceral - Smooth muscle cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 69: Neurons - Neuronal signaling" 6 "unprognostic (3.82e-4)" "unprognostic (7.11e-2)" "unprognostic (2.35e-1)" "prognostic favorable (1.66e-4)" "unprognostic (8.80e-3)" "unprognostic (3.15e-1)" "unprognostic (9.85e-2)" "unprognostic (7.43e-2)" "unprognostic (2.76e-1)" "unprognostic (2.05e-3)" "unprognostic (1.41e-2)" "unprognostic (4.47e-1)" "unprognostic (6.02e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (4.50e-3)" "unprognostic (9.12e-2)" MROH1 "HEATR7A, KIAA1833" ENSG00000179832 "Maestro heat like repeat family member 1" Q8NDA8 8 144148016-144261927 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 48.5" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 60.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024287, HPA044465" Approved Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Spleen - Immune response" "Cluster 24: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 72: Alveolar cells - Lung function" Nucleoplasm Cytosol "HPA024287: , HPA044465: AB_10960985" "unprognostic (1.25e-1)" "unprognostic (4.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (6.74e-4)" "unprognostic (2.97e-2)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (4.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.48e-2)" "unprognostic (6.64e-2)" "unprognostic (1.92e-1)" "prognostic favorable (3.65e-6)" "unprognostic (1.61e-3)" "unprognostic (1.97e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-2)" MSMB "IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94" ENSG00000263639 "Microseminoprotein beta" P08118 10 46033307-46048180 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "prostate: 9036.6" "Cell type enriched" "Detected in many" 11 "Prostatic glandular cells: 29753.7" "Cancer enriched" "Detected in many" 42 "prostate cancer: 3435.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "prostate cancer: 295.9" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB026357, HPA051257" Enhanced "Secreted in male reproductive system" "No annotated function" NA NA 6000000 "Cluster 64: Neuronal - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "CAB026357: , HPA051257: AB_2681410" "unprognostic (6.47e-2)" "unprognostic (7.21e-3)" "unprognostic (1.37e-2)" "unprognostic (8.18e-3)" "unprognostic (4.28e-3)" "unprognostic (9.24e-3)" "unprognostic (1.66e-1)" "unprognostic (8.66e-2)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" "unprognostic (2.01e-1)" "unprognostic (7.04e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.19e-4)" MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.8;skin 1: 31.1;stomach 1: 26.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.7;Distal enterocytes: 32.8;Gastric mucus-secreting cells: 92.0;Intestinal goblet cells: 25.9;Proximal enterocytes: 21.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 49.5" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Gastric mucus-secreting cells - Digestion" 3 Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" MUC1 "ADMCKD, ADMCKD1, Ca15-3, CD227, EMA, KL-6, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 419.1;stomach 1: 862.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 963.7;Alveolar cells type 2: 1456.7;Exocrine glandular cells: 951.7;Gastric mucus-secreting cells: 572.5;Ionocytes: 447.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Cancer enhanced" "Detected in all" "breast cancer: 211.1;pancreatic cancer: 218.2" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Mitotic cells (Colon), Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855, CAB080102, CAB080103" Enhanced Supported "Plasma membrane" "Secreted in other tissues" "No annotated function" NA NA 4000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , CAB080102: , CAB080103: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" MYH14 "DFNA4, FLJ13881, KIAA2034, MHC16, MYH17" ENSG00000105357 "Myosin heavy chain 14" Q7Z406 19 50188186-50310542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 72.6;skeletal muscle: 100.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 370.2;Paneth cells: 206.2;Proximal enterocytes: 357.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062391, HPA067889, HPA070260" Enhanced Approved Nucleoplasm NA NA 9600000 "Cluster 19: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 1 Nucleoplasm "HPA062391: AB_2684748, HPA067889: AB_2685917, HPA070260: AB_2686243" "unprognostic (2.52e-1)" "unprognostic (5.81e-2)" "unprognostic (9.63e-2)" "unprognostic (3.73e-3)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.71e-1)" "unprognostic (3.48e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "prognostic favorable (3.97e-8)" "prognostic favorable (7.83e-4)" "unprognostic (8.50e-2)" "unprognostic (3.12e-1)" "unprognostic (2.77e-1)" MYO1A "BBMI, DFNA48, MYHL" ENSG00000166866 "Myosin IA" Q9UBC5 12 57028517-57051198 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "intestine: 320.7" "Group enriched" "Detected in some" 5 "Distal enterocytes: 176.2;Proximal enterocytes: 643.2" "Group enriched" "Detected in many" 13 "colorectal cancer: 17.8;pancreatic cancer: 4.8;stomach cancer: 9.8" "Region enhanced" "Detected in many" "white matter: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 10.6;colorectal cancer: 18.5;Gastric cancer: 10.3" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA053490 Enhanced Approved Nucleoplasm NA NA "Cluster 25: Small intestine - Absorption" "Cluster 22: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm "HPA053490: AB_2682168" "unprognostic (2.77e-2)" "unprognostic (2.00e-3)" "unprognostic (1.04e-1)" "unprognostic (1.20e-1)" "unprognostic (7.31e-2)" "unprognostic (7.11e-2)" "unprognostic (4.57e-2)" "unprognostic (1.57e-1)" "unprognostic (6.04e-2)" "unprognostic (4.26e-2)" "unprognostic (8.96e-2)" "unprognostic (2.14e-1)" "unprognostic (2.38e-2)" "unprognostic (6.89e-2)" "unprognostic (5.01e-1)" "unprognostic (5.81e-2)" "unprognostic (8.72e-2)" MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195164 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 60.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 79.2;Distal enterocytes: 129.6;Inhibitory neurons: 87.2;Proximal enterocytes: 176.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 3 "Plasma membrane" "HPA040593: AB_10795525, HPA040902: AB_10796230, HPA069773: AB_2686194" "unprognostic (2.51e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-2)" "unprognostic (6.17e-3)" "unprognostic (2.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.26e-5)" "unprognostic (4.48e-2)" "prognostic favorable (1.45e-11)" "unprognostic (2.17e-3)" "unprognostic (1.50e-1)" "unprognostic (6.56e-2)" "unprognostic (3.28e-1)" MYO5C MGC74969 ENSG00000128833 "Myosin VC" Q9NQX4 15 52192322-52295804 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 65.0;Alveolar cells type 1: 106.5;Alveolar cells type 2: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Lung - Alveolar cells type 2, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020790, HPA032115, HPA032116" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" Cytosol Nucleoplasm "CAB020790: , HPA032115: AB_2674158, HPA032116: AB_2674159" "unprognostic (1.85e-1)" "unprognostic (1.29e-1)" "unprognostic (3.49e-2)" "prognostic favorable (5.18e-5)" "unprognostic (2.94e-1)" "unprognostic (4.01e-2)" "unprognostic (2.07e-1)" "unprognostic (1.53e-1)" "unprognostic (4.53e-3)" "unprognostic (1.02e-1)" "unprognostic (4.04e-3)" "unprognostic (4.82e-2)" "prognostic favorable (2.47e-5)" "prognostic favorable (5.82e-4)" "unprognostic (9.15e-2)" "unprognostic (2.34e-1)" "unprognostic (2.32e-1)" MYO6 "DFNA22, DFNB37, KIAA0389" ENSG00000196586 "Myosin VI" Q9UM54 6 75749201-75919537 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Hearing, Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cardiomyopathy, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 271.6;Oligodendrocytes: 380.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 5.4;MAIT T-cell: 3.0;memory CD4 T-cell: 1.7;memory CD8 T-cell: 3.1;naive CD8 T-cell: 3.0;NK-cell: 2.9" "Group enriched" "Detected in many" 7 "NK-cells: 2.9;T-cells: 5.4" "Cancer enhanced" "Detected in all" "prostate cancer: 146.4" "Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010762, HPA035482, HPA035483" Enhanced Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Kidney - Transmembrane transport" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 45: Non-specific - Mixed function" 3 Nucleoplasm "CAB010762: AB_477166, HPA035482: , HPA035483: AB_2674647" "unprognostic (6.29e-2)" "unprognostic (6.34e-2)" "unprognostic (3.63e-3)" "unprognostic (1.30e-1)" "unprognostic (8.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.41e-3)" "unprognostic (1.23e-2)" "unprognostic (1.23e-2)" "unprognostic (2.66e-2)" "unprognostic (7.78e-2)" "unprognostic (2.78e-2)" "prognostic favorable (1.27e-12)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (1.41e-1)" "unprognostic (2.49e-2)" NAPRT "NAPRT1, PP3856" ENSG00000147813 "Nicotinate phosphoribosyltransferase" Q6XQN6 8 143574785-143578649 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.5" "Cell type enhanced" "Detected in all" "Distal enterocytes: 338.9;Proximal enterocytes: 632.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023739, HPA024017, CAB068206, CAB068207" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 2300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB068206: AB_2665644, CAB068207: AB_2665681, HPA023739: AB_1854308, HPA024017: AB_1854309" "unprognostic (7.08e-2)" "unprognostic (1.55e-1)" "unprognostic (5.76e-3)" "unprognostic (2.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.30e-1)" "unprognostic (7.65e-2)" "unprognostic (2.19e-1)" "unprognostic (2.84e-1)" "unprognostic (1.08e-2)" "unprognostic (1.75e-1)" "unprognostic (4.13e-2)" "prognostic favorable (6.28e-4)" "unprognostic (6.02e-2)" "unprognostic (3.97e-1)" "unprognostic (2.28e-2)" "unprognostic (1.61e-2)" NBEAL2 KIAA0540 ENSG00000160796 "Neurobeachin like 2" Q6ZNJ1 3 46979666-47009704 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 133.3;Gastric mucus-secreting cells: 118.5;monocytes: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "neutrophil: 4.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.4" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051969 Approved NA NA 31000 "Cluster 28: Neutrophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Alveolar cells - Lung function" 3 "HPA051969: " "unprognostic (3.83e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-1)" "unprognostic (3.37e-2)" "unprognostic (5.99e-3)" "prognostic favorable (4.60e-4)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" "unprognostic (4.17e-1)" "unprognostic (6.27e-2)" "unprognostic (5.29e-2)" "unprognostic (1.06e-3)" "unprognostic (3.75e-1)" "unprognostic (6.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.80e-1)" "unprognostic (1.34e-2)" NCEH1 "AADACL1, KIAA1363, NCEH" ENSG00000144959 "Neutral cholesterol ester hydrolase 1" Q6PIU2 3 172630249-172711218 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026888, HPA043873" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Macrophages - Innate immune response" "Endoplasmic reticulum" "HPA026888: AB_10601557, HPA043873: " "unprognostic (3.19e-1)" "unprognostic (9.67e-2)" "unprognostic (5.74e-2)" "unprognostic (1.27e-1)" "unprognostic (6.88e-3)" "unprognostic (5.41e-2)" "unprognostic (3.29e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (5.29e-2)" "unprognostic (2.96e-2)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (2.81e-2)" "unprognostic (2.28e-1)" NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 96.1;skin 1: 110.2;vagina: 55.6" "Cell type enhanced" "Detected in many" "Club cells: 82.3;Ionocytes: 89.5;Squamous epithelial cells: 110.0;Suprabasal keratinocytes: 183.6;Syncytiotrophoblasts: 462.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 27.9" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" Receptor No No 170000 "Cluster 22: Eosinophils - Transcription" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 2 "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 54.5;brain: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.1;Excitatory neurons: 102.4;Proximal enterocytes: 57.7" "Cancer enhanced" "Detected in many" "testis cancer: 22.5" "Group enriched" "Detected in all" 4 "basal ganglia: 380.4;cerebral cortex: 233.6;white matter: 165.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 219.2;cerebral cortex: 173.3;hippocampal formation: 95.4" HPA008160 Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" 8 "Plasma membrane, Cytosol" "HPA008160: AB_1854450" "unprognostic (3.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-3)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-3)" "unprognostic (5.41e-3)" "unprognostic (2.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-1)" NPAS1 "bHLHe11, MOP5, PASD5" ENSG00000130751 "Neuronal PAS domain protein 1" Q99742 19 47019837-47045775 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;skin 1: 7.5" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 42.5;Gastric mucus-secreting cells: 25.4;Inhibitory neurons: 27.1;Oocytes: 86.8" "Cancer enhanced" "Detected in many" "testis cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 13.5" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA043364, HPA072259" Approved Approved Nucleoplasm NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" Nucleoplasm "HPA043364: , HPA072259: AB_2686500" "unprognostic (2.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.32e-4)" "unprognostic (1.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-3)" "unprognostic (2.21e-2)" "unprognostic (1.09e-1)" "unprognostic (3.75e-1)" "unprognostic (5.91e-2)" "unprognostic (2.64e-1)" "unprognostic (2.14e-8)" "unprognostic (8.82e-2)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (4.20e-2)" NPHS2 "PDCN, SRN1" ENSG00000116218 "NPHS2 stomatin family member, podocin" Q9NP85 1 179550539-179575952 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 141 "kidney: 248.0" "Cell type enriched" "Detected in some" 5 "Collecting duct cells: 35.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB037267, HPA049486" Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 13: Spermatids - Transcription" 1 "CAB037267: AB_261982, HPA049486: AB_2680788" "unprognostic (6.77e-2)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" NQO1 "DHQU, DIA4, DTD, NMOR1, QR1" ENSG00000181019 "NAD(P)H quinone dehydrogenase 1" P15559 16 69706996-69726668 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 508.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 259.9;Distal enterocytes: 235.4;Gastric mucus-secreting cells: 528.8;Ionocytes: 212.1;Suprabasal keratinocytes: 329.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007308, CAB012421" Enhanced Supported Cytosol NA NA 490000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" 2 Cytosol "CAB012421: , HPA007308: AB_1079501" "unprognostic (1.04e-2)" "unprognostic (1.95e-3)" "unprognostic (3.14e-1)" "unprognostic (3.76e-3)" "unprognostic (9.03e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.05e-3)" "unprognostic (1.97e-1)" "unprognostic (5.07e-2)" "unprognostic (1.24e-2)" "unprognostic (1.49e-2)" "unprognostic (2.25e-1)" "unprognostic (2.41e-2)" "unprognostic (6.36e-2)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.27e-1)" NRG4 HRG4 ENSG00000169752 "Neuregulin 4" Q8WWG1 15 75935969-76059795 "Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 4.2" "Cell type enhanced" "Detected in many" "Early spermatids: 18.6;Exocrine glandular cells: 22.4;Gastric mucus-secreting cells: 31.2;Oocytes: 27.9;Prostatic glandular cells: 15.6;Rod photoreceptor cells: 28.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010957 Uncertain "Secreted to digestive system" "Growth factor" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 2: Neurons - Nucleosome" "Cluster 56: Non-specific - Sensory perception" "Cluster 45: Non-specific - Mixed function" 4 "HPA010957: AB_1079504" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (3.94e-2)" "unprognostic (1.67e-2)" "unprognostic (5.66e-2)" "unprognostic (4.10e-2)" "unprognostic (1.12e-2)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (2.82e-5)" "unprognostic (1.91e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-5)" "unprognostic (8.28e-2)" "unprognostic (7.45e-2)" "unprognostic (1.08e-2)" "unprognostic (2.06e-1)" NUTM1 "C15orf55, DKFZp434O192, FAM22H, NUT" ENSG00000184507 "NUT midline carcinoma family member 1" Q86Y26 15 34343315-34357737 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 81 "testis: 19.2" "Cell type enriched" "Detected in some" 12 "Early spermatids: 117.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Gallbladder cancer: 1.9;head and neck cancer: 1.3" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA040421 Enhanced NA NA "Cluster 10: Testis - Spermatid development" "Cluster 15: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "Cluster 18: Early spermatids - Unknown function" 17 "HPA040421: AB_10793965" "unprognostic (4.14e-2)" "unprognostic (3.61e-1)" "unprognostic (2.11e-1)" "unprognostic (7.38e-2)" "unprognostic (1.99e-1)" "unprognostic (8.37e-2)" "unprognostic (8.66e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (5.55e-2)" "unprognostic (1.34e-2)" "unprognostic (5.97e-3)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (4.27e-2)" "unprognostic (4.79e-2)" OASL "OASL1, p59OASL, TRIP14" ENSG00000135114 "2'-5'-oligoadenylate synthetase like" Q15646 12 121017763-121039246 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.3;stomach 1: 21.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 69.0;Gastric mucus-secreting cells: 73.7;Hofbauer cells: 27.4;Intestinal goblet cells: 30.3;monocytes: 26.7;Paneth cells: 39.6;T-cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "pancreatic cancer: 43.2" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA001474 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 80: Non-specific - Transcription" 1 "Nucleoplasm, Cytosol" "HPA001474: AB_1079518" "unprognostic (2.39e-2)" "unprognostic (7.50e-2)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" "unprognostic (1.62e-2)" "unprognostic (6.22e-2)" "unprognostic (5.93e-3)" "prognostic unfavorable (9.20e-4)" "unprognostic (4.61e-1)" "prognostic unfavorable (3.70e-9)" "unprognostic (2.52e-1)" "unprognostic (2.72e-2)" "unprognostic (1.18e-1)" "unprognostic (3.17e-2)" OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 149.6" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 640.1;Proximal enterocytes: 708.4;Proximal tubular cells: 1226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA040979: AB_10795497, HPA041090: AB_10796236" "unprognostic (4.29e-1)" "unprognostic (2.69e-1)" "unprognostic (3.76e-2)" "prognostic favorable (7.37e-4)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (9.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-1)" "prognostic favorable (6.56e-4)" "prognostic unfavorable (6.89e-4)" "unprognostic (1.38e-1)" "prognostic favorable (2.67e-5)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (8.24e-3)" "prognostic favorable (2.34e-4)" OSBPL7 "MGC71150, ORP7" ENSG00000006025 "Oxysterol binding protein like 7" Q9BZF2 17 47807372-47821834 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 36.9;Gastric mucus-secreting cells: 109.1;Intestinal goblet cells: 25.6;Paneth cells: 26.3;Proximal enterocytes: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036076, HPA053083, HPA073967" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 46: Gastric mucus-secreting cells - Digestion" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036076: AB_10601042, HPA053083: AB_2682038, HPA073967: " "unprognostic (3.88e-2)" "unprognostic (2.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.55e-3)" "unprognostic (2.05e-3)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (3.33e-1)" "unprognostic (1.97e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.17e-1)" "unprognostic (1.36e-1)" "unprognostic (3.08e-1)" "prognostic favorable (1.19e-5)" OVOL2 "bA504H3.3, CHED, CHED1, HOVO2, ZNF339" ENSG00000125850 "Ovo like zinc finger 2" Q9BRP0 20 17956979-18059188 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Corneal dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 6.9;stomach 1: 7.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 24.3;Spermatocytes: 31.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Group enriched" "Detected in some" 5 "cerebral cortex: 5.3;hippocampal formation: 4.3" HPA038531 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 Nucleoplasm Cytosol "HPA038531: AB_10673012" "unprognostic (2.85e-2)" "unprognostic (5.13e-2)" "unprognostic (2.41e-2)" "unprognostic (7.35e-2)" "unprognostic (2.14e-1)" "unprognostic (5.14e-2)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.40e-1)" "unprognostic (2.61e-1)" "unprognostic (2.63e-2)" "unprognostic (1.62e-1)" "unprognostic (1.84e-4)" "unprognostic (4.77e-3)" "unprognostic (2.92e-1)" "unprognostic (2.57e-2)" "unprognostic (3.76e-2)" PARD6B PAR-6B ENSG00000124171 "Par-6 family cell polarity regulator beta" Q9BYG5 20 50731580-50756795 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 15.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 114.6;Glandular and luminal cells: 172.2;Proximal tubular cells: 101.5;Secretory cells: 100.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013376 Uncertain Supported Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 19 Cytosol "HPA013376: AB_1854972" "unprognostic (1.13e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (1.39e-3)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.02e-5)" "unprognostic (2.12e-1)" "unprognostic (1.37e-1)" "unprognostic (9.33e-2)" "prognostic unfavorable (8.38e-4)" "unprognostic (2.27e-1)" "prognostic favorable (6.38e-5)" "unprognostic (1.84e-2)" "unprognostic (1.97e-1)" "unprognostic (4.18e-2)" "unprognostic (1.07e-2)" PCDH1 pc42 ENSG00000156453 "Protocadherin 1" Q08174 5 141853090-141879246 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 58.8;Distal enterocytes: 46.8;Endothelial cells: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 76.0" "Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047720, HPA050538" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA 2500000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Nucleoplasm, Cell Junctions" Nucleoli "HPA047720: AB_2680130, HPA050538: AB_2681162" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (5.30e-2)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (4.16e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (1.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.43e-1)" "prognostic favorable (7.55e-5)" "unprognostic (2.05e-1)" "unprognostic (4.16e-2)" "unprognostic (3.13e-2)" "unprognostic (1.91e-1)" PDZD3 "FLJ22756, IKEPP, NHERF4, PDZK2" ENSG00000172367 "PDZ domain containing 3" Q86UT5 11 119185457-119190223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 18.8;kidney: 16.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 71.8;Gastric mucus-secreting cells: 27.1;Paneth cells: 29.9;Proximal enterocytes: 66.4;Proximal tubular cells: 26.5;Undifferentiated cells: 15.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.3;renal cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA077887 Enhanced NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 4 "HPA077887: " "unprognostic (2.42e-2)" "unprognostic (1.51e-1)" "unprognostic (2.65e-1)" "unprognostic (5.51e-2)" "unprognostic (1.59e-1)" "unprognostic (5.39e-2)" "unprognostic (6.07e-2)" "unprognostic (3.22e-1)" "unprognostic (1.86e-2)" "unprognostic (6.58e-3)" "unprognostic (9.00e-2)" "unprognostic (6.08e-2)" "unprognostic (8.72e-2)" "unprognostic (1.08e-1)" "unprognostic (3.37e-1)" "unprognostic (1.38e-1)" "unprognostic (3.41e-3)" PERP "dJ496H19.1, KCP1, KRTCAP1, PIGPC1, THW" ENSG00000112378 "P53 apoptosis effector related to PMP22" Q96FX8 6 138088505-138107419 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 760.9;skin 1: 1079.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3367.5;Squamous epithelial cells: 3783.0;Suprabasal keratinocytes: 7466.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 555.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 40.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 40.0" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022269 Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 7 "HPA022269: AB_1855219" "prognostic unfavorable (5.46e-4)" "unprognostic (2.90e-1)" "unprognostic (1.94e-1)" "unprognostic (5.18e-2)" "unprognostic (2.82e-2)" "unprognostic (1.27e-1)" "unprognostic (6.28e-3)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.92e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.05e-5)" "unprognostic (4.02e-2)" "unprognostic (6.05e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-1)" "unprognostic (1.94e-1)" "unprognostic (1.51e-2)" PHGR1 ENSG00000233041 "Proline, histidine and glycine rich 1" C9JFL3 15 40351033-40356434 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 2471.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 66526.7;Enteroendocrine cells: 8087.3;Intestinal goblet cells: 12406.1;Paneth cells: 19242.8;Proximal enterocytes: 47949.6" "Group enriched" "Detected in many" 16 "colorectal cancer: 248.3;stomach cancer: 94.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 203.2;colorectal cancer: 705.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA068787 Enhanced Approved Vesicles NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA068787: AB_2686035" "prognostic favorable (2.05e-4)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (1.18e-1)" "unprognostic (2.80e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-2)" PIP4K2C "FLJ22055, PIP5K2C" ENSG00000166908 "Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma" Q8TBX8 12 57591174-57603418 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028658 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Cytosol "Nucleoplasm, Plasma membrane" "HPA028658: AB_10601245" "unprognostic (7.84e-3)" "unprognostic (1.51e-1)" "unprognostic (2.42e-1)" "unprognostic (2.77e-2)" "unprognostic (2.49e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (7.98e-4)" "unprognostic (3.17e-2)" "unprognostic (6.00e-2)" "unprognostic (5.51e-2)" "unprognostic (1.75e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.06e-6)" "unprognostic (1.87e-1)" "unprognostic (2.16e-1)" "unprognostic (3.27e-1)" "unprognostic (3.42e-1)" PITPNM1 "DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1" ENSG00000110697 "Phosphatidylinositol transfer protein membrane associated 1" O00562 11 67491768-67506263 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 58.6;Cone photoreceptor cells: 79.9;Distal enterocytes: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060227 Approved Supported Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 17: Neuronal - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" 1 Cytosol Vesicles "HPA060227: AB_2684226" "unprognostic (1.13e-1)" "unprognostic (1.90e-1)" "unprognostic (1.69e-2)" "unprognostic (1.71e-1)" "unprognostic (2.83e-2)" "unprognostic (8.68e-2)" "unprognostic (8.16e-2)" "unprognostic (4.55e-2)" "unprognostic (1.77e-1)" "unprognostic (2.26e-2)" "unprognostic (4.61e-1)" "unprognostic (3.27e-2)" "unprognostic (2.32e-2)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (4.62e-2)" "unprognostic (5.69e-2)" PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 286.1;skin 1: 215.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 144.7;Distal enterocytes: 292.7;Extravillous trophoblasts: 188.1;Proximal enterocytes: 181.7;Suprabasal keratinocytes: 353.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 3 "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" PLA2G10 GXPLA2 ENSG00000069764 "Phospholipase A2 group X" O15496 16 14672548-14694308 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 26.2;stomach 1: 40.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 230.7;Enteroendocrine cells: 55.2;Exocrine glandular cells: 52.6;Extravillous trophoblasts: 64.7;Gastric mucus-secreting cells: 73.7;Intestinal goblet cells: 144.6;Paneth cells: 68.2" "Cancer enhanced" "Detected in many" "stomach cancer: 6.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.0;Gastric cancer: 4.1;pancreatic cancer: 4.4" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041893 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 40 "HPA041893: AB_10794495" "unprognostic (8.44e-3)" "unprognostic (2.37e-1)" "unprognostic (6.72e-2)" "prognostic favorable (5.74e-5)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (5.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.77e-2)" "unprognostic (2.72e-1)" "unprognostic (4.81e-2)" "unprognostic (2.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.08e-2)" "unprognostic (1.03e-1)" "unprognostic (2.30e-2)" "unprognostic (9.97e-3)" PLA2G4F PLA2G4F/Z ENSG00000168907 "Phospholipase A2 group IVF" Q68DD2 15 42139034-42156636 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 76.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 47.2;Distal enterocytes: 17.8;Gastric mucus-secreting cells: 17.7;Glandular and luminal cells: 13.9;Prostatic glandular cells: 14.6;Suprabasal keratinocytes: 25.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.4;prostate cancer: 3.4" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042713, HPA056752" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 13: Skin - Cornification" "Cluster 34: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 72: Alveolar cells - Lung function" Vesicles Nucleoplasm "HPA042713: AB_10793982, HPA056752: AB_2683226" "unprognostic (1.99e-1)" "unprognostic (6.21e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.06e-2)" "unprognostic (2.32e-3)" "unprognostic (1.48e-2)" "unprognostic (5.85e-2)" "unprognostic (2.25e-1)" "unprognostic (4.79e-2)" "unprognostic (6.65e-2)" "unprognostic (1.21e-2)" "unprognostic (9.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" "unprognostic (1.63e-1)" PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 65.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 78.8;Distal enterocytes: 73.3;Ionocytes: 52.3;Proximal enterocytes: 90.8;Proximal tubular cells: 152.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.4;naive B-cell: 8.3" "Lineage enriched" "Detected in many" 10 "B-cells: 17.4" "Cancer enhanced" "Detected in many" "Myeloma: 30.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells" HPA058997 Approved Approved Mitochondria NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 25: Small intestine - Absorption" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 5 Mitochondria "HPA058997: AB_2683874" "unprognostic (4.76e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (9.69e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" PLCH1 "DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3" ENSG00000114805 "Phospholipase C eta 1" Q4KWH8 3 155375580-155745071 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.2;retina: 12.1;testis: 11.0" "Group enriched" "Detected in many" 4 "Astrocytes: 88.9;Early spermatids: 260.1;Excitatory neurons: 121.6;Inhibitory neurons: 125.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 9.6" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036176, HPA057978" Uncertain Enhanced Vesicles NA NA "Cluster 28: Neuronal - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 8: Neurons - Neuronal signaling" 1 Vesicles "HPA036176: AB_10671837, HPA057978: AB_2683569" "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (2.17e-2)" "unprognostic (1.55e-2)" "unprognostic (3.50e-4)" "unprognostic (6.41e-2)" "unprognostic (2.94e-5)" "unprognostic (5.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.24e-3)" "unprognostic (4.84e-2)" "unprognostic (1.76e-2)" "prognostic favorable (3.03e-5)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-2)" PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 49.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 90.2;Basal respiratory cells: 60.5;Intestinal goblet cells: 57.5;Langerhans cells: 66.3;Proximal enterocytes: 49.1;Suprabasal keratinocytes: 58.3;Undifferentiated cells: 54.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Leydig cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 53: Non-specific - Glycosylation" "Cluster 15: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" Vesicles Cytosol "HPA001208: AB_1079631" "unprognostic (4.41e-3)" "unprognostic (3.77e-1)" "unprognostic (1.15e-1)" "unprognostic (6.23e-2)" "unprognostic (6.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.97e-1)" "unprognostic (9.21e-3)" "prognostic unfavorable (8.26e-5)" "unprognostic (1.06e-1)" "unprognostic (3.09e-3)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (8.98e-2)" "unprognostic (4.59e-2)" PLEKHA7 DKFZp686M22243 ENSG00000166689 "Pleckstrin homology domain containing A7" Q6IQ23 11 16777297-17014415 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 105.3;Gastric mucus-secreting cells: 46.6;Microglial cells: 46.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.7;MAIT T-cell: 1.9" "Group enriched" "Detected in many" 6 "granulocytes: 3.7;T-cells: 1.9" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038610, HPA066103" Approved Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Astrocytes - Unknown function" 6 "Nucleoplasm, Cell Junctions" Cytosol "HPA038610: AB_10671746, HPA066103: AB_2732738" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (3.81e-2)" "unprognostic (4.30e-2)" "unprognostic (2.51e-2)" "unprognostic (6.95e-3)" "unprognostic (2.81e-2)" "unprognostic (1.85e-2)" "unprognostic (2.65e-1)" "unprognostic (1.73e-1)" "unprognostic (2.65e-3)" "unprognostic (3.13e-2)" "prognostic favorable (1.89e-15)" "unprognostic (9.74e-2)" "unprognostic (1.17e-2)" "unprognostic (4.81e-1)" "unprognostic (2.65e-2)" PLEKHG6 "FLJ10665, MYOGEF" ENSG00000008323 "Pleckstrin homology and RhoGEF domain containing G6" Q3KR16 12 6310436-6328506 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.0;intestine: 38.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 93.2;Extravillous trophoblasts: 61.0;Paneth cells: 45.1;Proximal enterocytes: 60.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041459, HPA058230" Uncertain Supported "Cell Junctions,Centrosome" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 19: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 1 "Cell Junctions" Centrosome "HPA041459: AB_10794518, HPA058230: AB_2683645" "unprognostic (1.67e-1)" "unprognostic (9.93e-3)" "unprognostic (1.44e-1)" "unprognostic (8.03e-3)" "unprognostic (5.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.20e-2)" "unprognostic (1.22e-1)" "unprognostic (3.13e-1)" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (6.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (4.18e-2)" "unprognostic (5.73e-2)" PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 102.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 221.3;Ciliated cells: 211.6;Club cells: 236.1;Ductal cells: 340.4;Ionocytes: 251.4;Proximal enterocytes: 205.6;Rod photoreceptor cells: 242.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.3;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 40 "T-cells: 6.6" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" PLS1 ENSG00000120756 "Plastin 1" Q14651 3 142596393-142713664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 306.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 375.1;Intestinal goblet cells: 159.1;Paneth cells: 132.8;Proximal enterocytes: 319.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 36.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 2.6;NK-cells: 3.0;T-cells: 2.5" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000895, HPA055744, HPA061936" Enhanced Approved "Plasma membrane" NA NA 56000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Small intestine - Absorption" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" "HPA000895: , HPA055744: AB_2682903, HPA061936: " "unprognostic (1.29e-1)" "unprognostic (2.61e-1)" "unprognostic (3.15e-3)" "unprognostic (2.22e-2)" "unprognostic (1.20e-1)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.33e-1)" "unprognostic (7.78e-2)" "prognostic unfavorable (4.84e-4)" "unprognostic (3.14e-2)" "prognostic favorable (8.76e-6)" "unprognostic (1.99e-2)" "unprognostic (8.64e-2)" "unprognostic (7.22e-2)" "unprognostic (3.82e-2)" POF1B "FLJ22792, POF" ENSG00000124429 "POF1B actin binding protein" Q8WVV4 X 85277396-85379717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 52.5;skin 1: 120.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 130.2;Gastric mucus-secreting cells: 45.4;Intestinal goblet cells: 64.9;Paneth cells: 58.6;Proximal enterocytes: 60.3;Squamous epithelial cells: 40.3;Suprabasal keratinocytes: 66.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 44.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.9;naive B-cell: 2.2" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 60.1;Gastric cancer: 41.4" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002033, HPA050027" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 200000 "Cluster 14: Non-specific - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 59: Suprabasal keratinocytes - Cornification" "Golgi apparatus" Nucleoplasm "HPA002033: AB_1079650, HPA050027: " "unprognostic (2.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.54e-3)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.97e-1)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (1.86e-1)" "unprognostic (1.72e-1)" "unprognostic (1.30e-1)" "unprognostic (1.17e-2)" "unprognostic (2.50e-1)" "unprognostic (4.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.81e-1)" "unprognostic (5.57e-4)" "unprognostic (1.01e-2)" PPARG "NR1C3, PPARG1, PPARG2, PPARgamma" ENSG00000132170 "Peroxisome proliferator activated receptor gamma" P37231 3 12287368-12434356 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 157.6" "Cell type enhanced" "Detected in many" "Adipocytes: 238.2;Cytotrophoblasts: 114.9;Distal enterocytes: 118.5;Extravillous trophoblasts: 250.4;Syncytiotrophoblasts: 107.6" "Cancer enhanced" "Detected in all" "urothelial cancer: 33.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB004282, HPA051239, HPA063663" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" 12 "Nucleoplasm, Vesicles" "CAB004282: AB_628115, HPA051239: AB_2681400, HPA063663: AB_2685081" "unprognostic (7.35e-3)" "unprognostic (3.27e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-2)" "unprognostic (2.41e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (3.41e-5)" "unprognostic (9.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.59e-8)" "unprognostic (1.51e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-3)" "prognostic favorable (5.52e-5)" PPIF "Cyp-D, CypD, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355334 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Necrosis" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 411.2;Macrophages: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 75.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 544.5" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 320000 "Cluster 21: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Monocytes - Innate immune response" 13 Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" PPP1R1C Inhibitor-1-like ENSG00000150722 "Protein phosphatase 1 regulatory inhibitor subunit 1C" Q8WVI7 2 181954241-182131398 "Predicted intracellular proteins" "Cell cycle, Cell division" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 23.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 51.2;Early spermatids: 191.0;Late spermatids: 215.5;Spermatocytes: 118.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Sarcoma: 11.3;thyroid cancer: 13.2" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA055043 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 Nucleoplasm "Nucleoli, Golgi apparatus" "HPA055043: AB_2797251" "unprognostic (1.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.54e-3)" "unprognostic (1.08e-2)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (2.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.57e-2)" "unprognostic (6.59e-3)" "unprognostic (1.13e-1)" "unprognostic (7.98e-2)" "unprognostic (3.70e-2)" "unprognostic (1.00e-3)" "unprognostic (7.68e-2)" "unprognostic (3.07e-2)" "unprognostic (9.75e-3)" PRKCD ENSG00000163932 "Protein kinase C delta" Q05655 3 53156009-53192717 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 73.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 7 "dendritic cells: 55.3;granulocytes: 49.5;monocytes: 71.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Skeletal muscle - Macrophages, Stomach - Gastric mucous cells" "Group enriched" "Detected in all" 5 "basal ganglia: 121.5;thalamus: 334.8" "Low region specificity" "Detected in all" "HPA001863, HPA001890, CAB010469, CAB013225" Enhanced Enhanced "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA 30000 "Cluster 29: Non-specific - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" 9 Cytosol "Endoplasmic reticulum, Golgi apparatus" "CAB010469: AB_632229, CAB013225: , HPA001863: AB_1079627, HPA001890: AB_1079628" "unprognostic (3.59e-1)" "unprognostic (4.85e-2)" "unprognostic (2.66e-2)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.24e-4)" "prognostic favorable (9.01e-4)" "unprognostic (1.95e-2)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.06e-3)" "unprognostic (2.95e-3)" PROM2 ENSG00000155066 "Prominin 2" Q8N271 2 95274449-95291308 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 85.6;skin 1: 58.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 38.2;Club cells: 52.5;Ionocytes: 49.3;Squamous epithelial cells: 39.8;Suprabasal keratinocytes: 50.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 80.1;head and neck cancer: 80.5" "Kidney - Ascending Loop of Henle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB046005, HPA063728" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 2 "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB046005: AB_2284371, HPA063728: AB_2685104" "prognostic unfavorable (2.16e-4)" "unprognostic (1.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.46e-2)" "unprognostic (4.59e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-2)" PRR15 ENSG00000176532 "Proline rich 15" Q8IV56 7 29563835-29567293 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 60.3;intestine: 78.6;stomach 1: 48.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 215.5;Granulosa cells: 134.7;Oocytes: 95.6;Proximal enterocytes: 117.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 75.5" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA040996, HPA048121" Enhanced Uncertain "Vesicles,Cell Junctions" NA NA "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 Vesicles "Cell Junctions" "HPA040996: AB_2677241, HPA048121: AB_2680271" "unprognostic (5.46e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "prognostic favorable (6.37e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (3.69e-3)" "unprognostic (1.25e-1)" "prognostic favorable (1.83e-6)" "unprognostic (1.30e-2)" "unprognostic (5.71e-2)" "unprognostic (2.33e-3)" "unprognostic (1.58e-2)" PRSS12 "BSSP-3, MRT1" ENSG00000164099 "Serine protease 12" P56730 4 118280038-118353003 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 45.4;Cytotrophoblasts: 48.6;Distal enterocytes: 23.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "choroid plexus: 32.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 86.9" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035054 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" "HPA035054: AB_10603990" "unprognostic (4.30e-2)" "unprognostic (1.04e-2)" "unprognostic (2.55e-1)" "unprognostic (4.41e-2)" "prognostic favorable (2.66e-4)" "prognostic favorable (1.03e-4)" "unprognostic (4.21e-1)" "unprognostic (3.48e-2)" "unprognostic (7.83e-2)" "unprognostic (6.38e-2)" "unprognostic (1.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.29e-1)" "unprognostic (1.85e-1)" "unprognostic (9.55e-2)" "unprognostic (1.09e-1)" PRSS22 "BSSP-4, hBSSP-4, SP001LA" ENSG00000005001 "Serine protease 22" Q9GZN4 16 2852730-2858170 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 77.4;salivary gland: 26.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 149.0;Club cells: 240.4;Ductal cells: 104.1;Ionocytes: 445.1;Secretory cells: 110.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 24.6" "Colon - Colon enterocytes, Kidney - Endothelial cells, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in some" "cerebral cortex: 2.6" "Low region specificity" "Detected in all" HPA049161 Approved Approved Nucleoplasm "Secreted in other tissues" Enzyme NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "HPA049161: AB_2680660" "unprognostic (1.45e-1)" "unprognostic (9.80e-2)" "unprognostic (3.50e-2)" "unprognostic (4.48e-1)" "unprognostic (2.29e-4)" "unprognostic (2.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.52e-2)" "unprognostic (5.06e-1)" "unprognostic (7.52e-2)" "unprognostic (3.74e-3)" "unprognostic (4.12e-1)" "unprognostic (2.32e-4)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" PSAPL1 ENSG00000178597 "Prosaposin like 1" Q6NUJ1 4 7430285-7434930 "Predicted secreted proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 95.4;stomach 1: 37.6" "Cell type enriched" "Detected in some" 8 "Gastric mucus-secreting cells: 54.2" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.7;melanoma: 2.5;pancreatic cancer: 2.0;stomach cancer: 3.0;urothelial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.3;Esophageal cancer: 2.0" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038013, HPA038482" Approved Enhanced Cytosol "Secreted - unknown location" Other NA NA 31000 "Cluster 13: Skin - Cornification" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" Cytosol "HPA038013: AB_10673652, HPA038482: AB_2676037" "unprognostic (2.64e-2)" "unprognostic (2.40e-1)" "unprognostic (9.33e-2)" "unprognostic (2.40e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-3)" "unprognostic (2.52e-1)" "unprognostic (2.08e-2)" "unprognostic (2.75e-1)" "unprognostic (2.63e-3)" PTER ENSG00000165983 "Phosphotriesterase related" Q96BW5 10 16436943-16513745 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 42.4" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038044, HPA038045" Approved Approved Nucleoplasm,Cytosol NA NA 8600 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 Nucleoplasm Cytosol "HPA038044: AB_2675803, HPA038045: AB_10672616" "unprognostic (5.57e-2)" "unprognostic (1.04e-1)" "unprognostic (2.76e-2)" "unprognostic (3.14e-2)" "unprognostic (9.72e-3)" "unprognostic (2.45e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.17e-1)" "unprognostic (4.51e-2)" "unprognostic (2.86e-1)" "unprognostic (2.05e-3)" "unprognostic (1.86e-1)" "prognostic favorable (6.52e-6)" "unprognostic (2.24e-1)" "unprognostic (1.79e-1)" "unprognostic (1.54e-2)" "unprognostic (5.36e-3)" PTGR1 "LTB4DH, ZADH3" ENSG00000106853 "Prostaglandin reductase 1" Q14914 9 111549722-111599893 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 271.0;liver: 576.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 419.1;Hepatocytes: 977.8;Proximal enterocytes: 1232.0;Proximal tubular cells: 457.0;Suprabasal keratinocytes: 857.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 6.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 6.0" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036724 Enhanced NA NA 2400000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "HPA036724: AB_10670239" "unprognostic (1.54e-1)" "unprognostic (2.23e-1)" "unprognostic (1.10e-2)" "unprognostic (3.02e-3)" "unprognostic (8.46e-2)" "unprognostic (1.02e-3)" "unprognostic (1.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (3.48e-1)" "prognostic favorable (5.53e-4)" "unprognostic (2.25e-1)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (5.22e-2)" PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase receptor type H" Q9HD43 19 55181247-55209506 "Enzymes, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 23.4;intestine: 66.7;stomach 1: 23.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 74.7;Gastric mucus-secreting cells: 56.6;Intestinal goblet cells: 28.3;Paneth cells: 35.3;Proximal enterocytes: 106.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008708 Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 30: White matter - Myelination" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" 4 "Nuclear speckles, Cytosol" "Plasma membrane" "HPA008708: " "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" RAB11FIP1 "FLJ22524, FLJ22622, Rab11-FIP1, RCP" ENSG00000156675 "RAB11 family interacting protein 1" Q6WKZ4 8 37858618-37899497 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1714.2;Glandular and luminal cells: 908.0;Mucus glandular cells: 792.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 7 "choroid plexus: 85.3" "Immune cell enhanced" "Detected in all" "neutrophil: 102.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 102.1" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017037, HPA023904, HPA024010, HPA025960" Enhanced Enhanced Vesicles No No "Cluster 7: Non-specific - Innate immune response" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 Vesicles "CAB017037: , HPA023904: AB_1855990, HPA024010: AB_1855991, HPA025960: AB_1855992" "unprognostic (1.62e-2)" "unprognostic (3.47e-2)" "unprognostic (3.22e-3)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "prognostic favorable (6.61e-4)" "unprognostic (4.32e-1)" "unprognostic (4.50e-3)" "unprognostic (1.58e-1)" "unprognostic (4.72e-2)" "unprognostic (2.82e-3)" "unprognostic (2.73e-2)" "prognostic favorable (1.14e-6)" "unprognostic (4.94e-2)" "unprognostic (8.41e-2)" "unprognostic (9.99e-2)" "unprognostic (1.50e-1)" RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 411.4;skin 1: 203.3" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 343.8;Suprabasal keratinocytes: 515.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3;naive CD4 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010940, CAB033645" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 2 "Plasma membrane" "CAB033645: AB_1128883, HPA010940: " "unprognostic (2.43e-1)" "unprognostic (4.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (4.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (1.38e-6)" "unprognostic (2.31e-2)" "unprognostic (3.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.94e-2)" RAB27A "GS2, HsT18676, RAB27, RAM" ENSG00000069974 "RAB27A, member RAS oncogene family" P51159 15 55202966-55319113 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Exocytosis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 117.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 126.7;Intestinal goblet cells: 279.6;Melanocytes: 104.8;NK-cells: 112.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 262.4" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 102.5" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001333, CAB034046" Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 16: Intestinal goblet cells - Mucin production" 6 "CAB034046: AB_2176724, HPA001333: AB_1079730" "prognostic favorable (2.56e-4)" "unprognostic (9.75e-2)" "unprognostic (2.01e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" "unprognostic (1.73e-1)" "unprognostic (2.32e-1)" "unprognostic (2.62e-1)" "unprognostic (2.77e-1)" "unprognostic (6.24e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.23e-2)" "unprognostic (4.34e-1)" "unprognostic (7.95e-3)" "unprognostic (4.32e-1)" RAB27B ENSG00000041353 "RAB27B, member RAS oncogene family" O00194 18 54717860-54895516 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 43.0" "Cell type enhanced" "Detected in many" "Early spermatids: 258.1;Gastric mucus-secreting cells: 161.5;granulocytes: 226.8;Late spermatids: 229.5;Prostatic glandular cells: 117.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.2;NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Mast cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017712, HPA019849" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 6500000 "Cluster 24: Non-specific - Transcription" "Cluster 48: Stomach - Proteolysis" "Cluster 14: Neurons - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Granulocytes - Unknown function" 7 "Golgi apparatus, Plasma membrane" Cytosol "CAB017712: , HPA019849: AB_1856000" "unprognostic (1.59e-1)" "unprognostic (5.20e-2)" "unprognostic (9.89e-3)" "unprognostic (7.51e-2)" "unprognostic (8.89e-2)" "unprognostic (1.84e-2)" "unprognostic (1.52e-1)" "unprognostic (2.73e-3)" "unprognostic (6.82e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (1.39e-2)" "unprognostic (1.20e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (5.75e-1)" "unprognostic (1.29e-1)" RALGPS1 "KIAA0351, RALGEF2, RALGPS1A" ENSG00000136828 "Ral GEF with PH domain and SH3 binding motif 1" Q5JS13 9 126914774-127223166 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 83.3;Excitatory neurons: 102.0;Inhibitory neurons: 157.5;Oligodendrocytes: 150.1;Rod photoreceptor cells: 140.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014749 Uncertain NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" "HPA014749: " "unprognostic (3.49e-2)" "unprognostic (3.35e-2)" "unprognostic (4.14e-2)" "unprognostic (2.06e-1)" "unprognostic (2.00e-1)" "unprognostic (5.10e-2)" "unprognostic (1.09e-1)" "unprognostic (6.69e-3)" "unprognostic (3.47e-1)" "unprognostic (4.68e-2)" "unprognostic (5.02e-3)" "unprognostic (3.49e-1)" "prognostic favorable (6.20e-11)" "unprognostic (4.79e-2)" "unprognostic (7.68e-2)" "unprognostic (3.75e-2)" "unprognostic (3.24e-3)" RASAL1 RASAL ENSG00000111344 "RAS protein activator like 1" O95294 12 113098819-113136239 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 57.7;salivary gland: 27.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 31.1;Excitatory neurons: 13.5;Gastric mucus-secreting cells: 45.4;Oligodendrocytes: 43.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 12.8" "Colon - Colon enterocytes, Liver - Cholangiocyte, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 18.4;cerebral cortex: 18.8;hippocampal formation: 28.0" HPA041650 Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 34: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 75: Serous glandular cells - Salivary secretion" "Plasma membrane, Cytosol" "Cell Junctions" "HPA041650: AB_2677598" "unprognostic (9.95e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-3)" "prognostic unfavorable (3.26e-5)" "unprognostic (1.27e-2)" "unprognostic (7.73e-3)" "unprognostic (1.57e-2)" "unprognostic (1.43e-2)" "unprognostic (2.65e-1)" "unprognostic (3.02e-3)" "unprognostic (3.16e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-2)" "unprognostic (2.85e-3)" "unprognostic (1.15e-1)" "unprognostic (3.34e-2)" "unprognostic (2.64e-1)" RASEF "FLJ31614, RAB45, TSG" ENSG00000165105 "RAS and EF-hand domain containing" Q8IZ41 9 82979590-83063177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 39.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 310.7;Glandular and luminal cells: 82.4;Intestinal goblet cells: 91.9;Mucus glandular cells: 83.6;Prostatic glandular cells: 133.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021431, HPA078596" Approved Approved Microtubules NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 46: Gastric mucus-secreting cells - Digestion" Microtubules "HPA021431: AB_1856087, HPA078596: " "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.26e-1)" "unprognostic (2.59e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-3)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (8.60e-2)" "unprognostic (1.66e-3)" "unprognostic (3.67e-1)" "unprognostic (1.41e-3)" "unprognostic (5.07e-2)" "unprognostic (6.05e-3)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" RASSF6 ENSG00000169435 "Ras association domain family member 6" Q6ZTQ3 4 73571550-73620631 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.8;stomach 1: 34.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 67.0;Enteroendocrine cells: 70.2;Exocrine glandular cells: 67.8;Gastric mucus-secreting cells: 146.2;Intestinal goblet cells: 65.3;Salivary duct cells: 69.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "choroid plexus: 11.3" "Immune cell enriched" "Detected in single" 8 "memory B-cell: 2.7" "Lineage enriched" "Detected in single" 13 "B-cells: 2.7" "Cancer enhanced" "Detected in many" "lymphoma: 27.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA037712 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 48: Stomach - Proteolysis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Nucleoplasm, Golgi apparatus" "HPA037712: AB_2675625" "unprognostic (9.08e-3)" "unprognostic (1.23e-1)" "unprognostic (4.82e-2)" "unprognostic (3.09e-3)" "unprognostic (1.02e-1)" "unprognostic (1.55e-1)" "unprognostic (8.47e-2)" "unprognostic (2.05e-1)" "unprognostic (1.01e-1)" "unprognostic (3.11e-2)" "unprognostic (6.76e-2)" "unprognostic (3.89e-2)" "unprognostic (5.86e-2)" "unprognostic (2.95e-1)" "unprognostic (8.97e-3)" "unprognostic (5.03e-2)" RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 351.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 91.9" "Immune cell enhanced" "Detected in many" "neutrophil: 136.7" "Group enriched" "Detected in many" 13 "dendritic cells: 34.4;granulocytes: 136.7;monocytes: 45.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Heart muscle - Macrophages, Prostate - Prostate glandular cells, Skeletal muscle - Macrophages, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" 4 "Nucleoplasm, Cytosol" "HPA006347: AB_2181208" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.49e-3)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-2)" "unprognostic (7.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (9.42e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-16)" "unprognostic (1.62e-2)" "unprognostic (9.81e-2)" "unprognostic (1.72e-1)" "unprognostic (5.77e-2)" RDH12 "FLJ30273, LCA13, RP53, SDR7C2" ENSG00000139988 "Retinol dehydrogenase 12" Q96NR8 14 67701886-67734451 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Vision" Oxidoreductase "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "retina: 216.0;skin 1: 61.8" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 292.3;Rod photoreceptor cells: 445.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 76: Retina - Visual perception" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" 1 "unprognostic (4.25e-3)" "unprognostic (4.50e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (2.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.69e-2)" "unprognostic (2.72e-3)" "unprognostic (7.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.42e-2)" "unprognostic (6.47e-2)" "unprognostic (7.83e-2)" "unprognostic (3.58e-1)" "unprognostic (3.92e-1)" RECQL5 "FLJ90603, RecQ5" ENSG00000108469 "RecQ like helicase 5" O94762 17 75626845-75667189 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, DNA replication" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029971 Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 16: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" Nucleoplasm Cytosol "HPA029971: AB_10611389" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "prognostic unfavorable (1.73e-6)" "unprognostic (8.39e-2)" "unprognostic (2.34e-2)" "unprognostic (3.57e-3)" "unprognostic (5.83e-2)" "unprognostic (3.15e-1)" "unprognostic (5.84e-2)" "prognostic favorable (4.34e-4)" "unprognostic (4.07e-2)" "unprognostic (7.01e-2)" "unprognostic (6.37e-2)" "unprognostic (1.42e-1)" "unprognostic (4.78e-1)" "unprognostic (1.81e-2)" REEP4 "C8orf20, FLJ22246, FLJ22277, PP432, Yip2c" ENSG00000168476 "Receptor accessory protein 4" Q9H6H4 8 22138020-22141951 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 86.8;skin 1: 88.2" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 93.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042683 Approved Supported "Endoplasmic reticulum" No Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 92 "Endoplasmic reticulum" "HPA042683: AB_2571730" "unprognostic (2.38e-1)" "unprognostic (9.96e-3)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (3.41e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (7.15e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.88e-5)" "unprognostic (5.72e-2)" "unprognostic (1.06e-1)" "unprognostic (2.25e-1)" "unprognostic (6.65e-2)" REG4 "GISP, REG-IV, RELP" ENSG00000134193 "Regenerating family member 4" Q9BYZ8 1 119794017-119811580 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 644.3" "Group enriched" "Detected in some" 47 "Enteroendocrine cells: 7572.0;Intestinal goblet cells: 4357.1" "Group enriched" "Detected in many" 21 "colorectal cancer: 180.6;pancreatic cancer: 215.1;stomach cancer: 162.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive CD8 T-cell: 24.7" "Lineage enriched" "Detected in single" 100 "T-cells: 24.7" "Group enriched" "Detected in many" 4 "colorectal cancer: 119.0;Esophageal cancer: 120.2;Gastric cancer: 177.8;pancreatic cancer: 62.6" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025867, HPA046555" Enhanced "Secreted to digestive system" "No annotated function" NA NA 460000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 20: Enteroendocrine cells - Hormone signaling" "CAB025867: , HPA046555: AB_2679696" "unprognostic (3.22e-2)" "unprognostic (2.57e-1)" "unprognostic (2.86e-3)" "unprognostic (2.57e-1)" "unprognostic (6.52e-2)" "unprognostic (6.20e-3)" "unprognostic (1.11e-1)" "unprognostic (1.64e-2)" "unprognostic (7.10e-2)" "unprognostic (7.85e-2)" "unprognostic (2.99e-1)" "unprognostic (5.12e-3)" "unprognostic (8.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-3)" REP15 RAB15EP ENSG00000174236 "RAB15 effector protein" Q6BDI9 12 27696447-27697596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "intestine: 57.4;stomach 1: 75.1" "Cell type enriched" "Detected in many" 4 "Intestinal goblet cells: 510.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "testis cancer: 11.6" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040448, HPA059868" Approved NA NA "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" 4 "HPA040448: AB_10964206, HPA059868: AB_2684148" "unprognostic (4.13e-2)" "unprognostic (4.32e-3)" "prognostic favorable (9.43e-5)" "unprognostic (7.29e-2)" "unprognostic (7.42e-5)" "unprognostic (4.63e-2)" "unprognostic (2.31e-1)" "unprognostic (1.87e-3)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (5.13e-3)" "unprognostic (3.00e-1)" "unprognostic (5.30e-2)" "unprognostic (3.52e-1)" "unprognostic (2.76e-1)" "unprognostic (5.27e-5)" "unprognostic (1.77e-1)" RFLNA "Cfm2, FAM101A, FLJ44614, RefilinA" ENSG00000178882 "Refilin A" Q6ZTI6 12 123973241-124316024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "stomach 1: 92.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 27.5;Enteroendocrine cells: 14.7;Gastric mucus-secreting cells: 111.4;Intestinal goblet cells: 47.7;Paneth cells: 17.0;Undifferentiated cells: 14.4" "Cancer enhanced" "Detected in many" "stomach cancer: 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA078021 Enhanced Approved "Focal adhesion sites" NA NA "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Focal adhesion sites" "HPA078021: AB_2732368" "unprognostic (1.71e-1)" "unprognostic (6.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.36e-1)" "unprognostic (3.15e-2)" "unprognostic (8.78e-4)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.16e-5)" "unprognostic (8.87e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-3)" "unprognostic (1.15e-3)" "unprognostic (1.77e-8)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "unprognostic (6.27e-2)" "unprognostic (1.37e-2)" RHOV "ARHV, Chp, WRCH2" ENSG00000104140 "Ras homolog family member V" Q96L33 15 40872214-40874234 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 205.8;skin 1: 125.8;vagina: 89.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 142.3;Club cells: 178.0;Paneth cells: 196.3;Squamous epithelial cells: 402.2;Suprabasal keratinocytes: 328.6" "Cancer enhanced" "Detected in many" "cervical cancer: 91.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 134.6" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053343 Enhanced NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "HPA053343: AB_2682122" "unprognostic (1.42e-1)" "unprognostic (2.06e-1)" "unprognostic (8.29e-3)" "unprognostic (4.34e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.19e-4)" "unprognostic (3.29e-3)" "unprognostic (1.05e-1)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (8.43e-3)" "unprognostic (5.63e-3)" RHPN2 ENSG00000131941 "Rhophilin Rho GTPase binding protein 2" Q8IUC4 19 32978592-33064888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 58.8;Gastric mucus-secreting cells: 90.8;Glandular and luminal cells: 105.5;Muller glia cells: 66.5;Prostatic glandular cells: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051749 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA051749: AB_2681589" "unprognostic (1.18e-1)" "unprognostic (1.33e-1)" "unprognostic (1.17e-2)" "unprognostic (3.65e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.08e-3)" "unprognostic (2.32e-1)" "unprognostic (5.07e-3)" "unprognostic (3.01e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.22e-8)" "unprognostic (3.74e-2)" "unprognostic (4.44e-2)" "unprognostic (5.81e-2)" "unprognostic (4.40e-2)" RIPK4 "ANKK2, ANKRD3, DIK, PKK, RIP4" ENSG00000183421 "Receptor interacting serine/threonine kinase 4" P57078 21 41739369-41767089 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 70.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 55.8;Gastric mucus-secreting cells: 56.0;Glandular and luminal cells: 167.3;Squamous epithelial cells: 68.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 6 "choroid plexus: 7.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA030942 Enhanced NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 7 "HPA030942: AB_2732462" "unprognostic (8.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.32e-3)" "unprognostic (7.87e-2)" "unprognostic (1.24e-1)" "unprognostic (5.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.88e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (6.22e-5)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.98e-2)" "prognostic favorable (6.52e-4)" "unprognostic (2.69e-1)" "unprognostic (2.95e-3)" "unprognostic (2.28e-1)" "unprognostic (2.78e-2)" RPS6KA1 "HU-1, MAPKAPK1, p90Rsk, RSK1" ENSG00000117676 "Ribosomal protein S6 kinase A1" Q15418 1 26529761-26575030 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 69.0;Proximal enterocytes: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003852, HPA007981" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 74: Neutrophils - Degranulation" 7 Cytosol Nucleoplasm "CAB003852: AB_289590, HPA007981: AB_1079850" "unprognostic (1.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.61e-3)" "prognostic favorable (7.20e-7)" "unprognostic (7.35e-2)" "unprognostic (3.69e-1)" "unprognostic (6.93e-3)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (7.51e-3)" "unprognostic (2.37e-2)" "unprognostic (9.64e-2)" "prognostic favorable (1.84e-4)" "prognostic favorable (4.58e-4)" "unprognostic (4.77e-2)" "unprognostic (7.61e-2)" "prognostic favorable (8.33e-4)" S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3615.1;vagina: 1138.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2161.5;Distal enterocytes: 1962.1;Proximal enterocytes: 1520.7;Squamous epithelial cells: 3669.3;Suprabasal keratinocytes: 5409.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1004.1" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" 3 "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 1947.5;epididymis: 1337.7" "Group enriched" "Detected in many" 4 "Ciliated cells: 870.3;Glandular and luminal cells: 2561.3" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 971.9" "Region enhanced" "Detected in some" "medulla oblongata: 7.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 15.0" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" "No annotated function" NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" Vesicles "HPA034584: AB_10602221" "unprognostic (7.73e-2)" "unprognostic (3.77e-1)" "prognostic favorable (1.22e-4)" "prognostic favorable (1.54e-8)" "unprognostic (2.98e-2)" "unprognostic (1.86e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (6.87e-3)" "prognostic favorable (6.36e-4)" "unprognostic (5.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" "unprognostic (3.35e-1)" SCIN KIAA1905 ENSG00000006747 Scinderin Q9Y6U3 7 12570577-12660182 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 45.1;kidney: 45.4;placenta: 75.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 299.5;Early spermatids: 117.4;Paneth cells: 162.4;Proximal enterocytes: 290.5" "Cancer enhanced" "Detected in many" "renal cancer: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020518, HPA024264" Enhanced Approved "Plasma membrane,Cytosol" No No 2300000 "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane" Cytosol "HPA020518: AB_1856619, HPA024264: AB_1856621" "unprognostic (3.68e-1)" "unprognostic (4.98e-2)" "unprognostic (5.05e-1)" "unprognostic (2.47e-1)" "unprognostic (1.50e-1)" "unprognostic (5.98e-2)" "unprognostic (3.64e-5)" "unprognostic (1.31e-2)" "unprognostic (3.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.24e-1)" "prognostic favorable (4.26e-8)" "unprognostic (3.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.13e-2)" "unprognostic (3.18e-1)" SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 190.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 224.1;Alveolar cells type 2: 194.9;Distal enterocytes: 138.4;Glandular and luminal cells: 183.0;Intestinal goblet cells: 204.9;Salivary duct cells: 178.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 18 "choroid plexus: 243.0" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA012743 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" 3 "HPA012743: AB_1856627" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (5.16e-2)" "unprognostic (6.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.62e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.86e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (5.56e-2)" "prognostic favorable (9.21e-8)" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" SCNN1B ENaCbeta ENSG00000168447 "Sodium channel epithelial 1 subunit beta" P51168 16 23278231-23381294 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 80.5;intestine: 91.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.7;Club cells: 56.9;Distal enterocytes: 242.3;Ionocytes: 48.6;Salivary duct cells: 76.9;Suprabasal keratinocytes: 51.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 26.4" "Region enriched" "Detected in single" 9 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Myeloma: 32.1;Sarcoma: 36.5;thyroid cancer: 9.6" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 5 "cerebellum: 1.0" "Low region specificity" "Detected in many" HPA015612 Uncertain NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 54: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 2 "HPA015612: AB_1856629" "unprognostic (7.45e-2)" "unprognostic (1.76e-3)" "unprognostic (1.39e-1)" "unprognostic (6.74e-3)" "unprognostic (1.74e-2)" "unprognostic (5.11e-3)" "unprognostic (7.74e-2)" "unprognostic (5.49e-3)" "unprognostic (2.60e-1)" "unprognostic (2.40e-1)" "unprognostic (3.68e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.32e-1)" "unprognostic (4.66e-2)" "unprognostic (3.93e-3)" "unprognostic (1.25e-2)" SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 477.8;liver: 472.9;skin 1: 433.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 232.8;Cholangiocytes: 259.5;Hepatocytes: 515.2;Squamous epithelial cells: 275.0;Suprabasal keratinocytes: 456.1;Syncytiotrophoblasts: 421.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 36.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 564.7" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" "No annotated function" NA NA 63100000 3100000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "Focal adhesion sites" "CAB002424: AB_442050, HPA006185: AB_1857705, HPA067477: " "prognostic unfavorable (2.22e-4)" "unprognostic (6.80e-3)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (4.02e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (3.66e-1)" "unprognostic (2.27e-3)" "unprognostic (1.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.62e-2)" "unprognostic (1.52e-1)" SDCBP2 "SITAC18, ST-2" ENSG00000125775 "Syndecan binding protein 2" Q9H190 20 1309909-1329139 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 137.9;intestine: 133.0;stomach 1: 99.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 217.8;Distal enterocytes: 700.5;Ionocytes: 269.1;Paneth cells: 640.0;Proximal enterocytes: 476.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gastric cancer: 28.9" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005804, HPA064490" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Non-specific - Mixed function" 49 Nucleoplasm "Golgi apparatus, Cytosol" "HPA005804: , HPA064490: AB_2732713" "unprognostic (1.96e-2)" "unprognostic (5.44e-2)" "unprognostic (2.37e-1)" "unprognostic (5.85e-2)" "unprognostic (2.54e-1)" "unprognostic (2.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (1.01e-1)" "unprognostic (3.78e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.17e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.37e-4)" SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 50.4;lung: 33.4;skin 1: 60.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 213.2;Alveolar cells type 2: 467.7;Basal respiratory cells: 330.7;Ionocytes: 287.9;Suprabasal keratinocytes: 235.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 36 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 48 "B-cells: 4.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 15.5" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 35: Respiratory epithelial cells - Unknown function" 9 "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969504-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 59.0;Hepatocytes: 46.1;Intestinal goblet cells: 35.2;Paneth cells: 37.8;Proximal enterocytes: 45.4;Undifferentiated cells: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" "Developmental protein" NA NA 1300000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" SERINC2 "FKSG84, PRO0899, TDE2, TDE2L" ENSG00000168528 "Serine incorporator 2" Q96SA4 1 31409565-31434680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 229.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 358.9;Cytotrophoblasts: 454.0;Distal enterocytes: 545.6;Ductal cells: 715.9;Proximal enterocytes: 402.0;Syncytiotrophoblasts: 404.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 10.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 10.4" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005974 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" Nucleoplasm "HPA005974: AB_10603239" "unprognostic (1.41e-1)" "unprognostic (3.70e-3)" "unprognostic (8.78e-3)" "prognostic favorable (1.69e-7)" "unprognostic (6.78e-2)" "unprognostic (5.31e-2)" "prognostic unfavorable (2.11e-4)" "prognostic unfavorable (5.70e-4)" "unprognostic (3.12e-2)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.09e-2)" "unprognostic (3.74e-2)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (4.63e-3)" "unprognostic (2.67e-2)" SFN YWHAS ENSG00000175793 Stratifin P31947 1 26863149-26864456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2392.4;skin 1: 1181.2;vagina: 671.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 7039.2;Basal squamous epithelial cells: 1977.4;Squamous epithelial cells: 3788.2;Suprabasal keratinocytes: 12189.4" "Cancer enhanced" "Detected in all" "cervical cancer: 1510.8;head and neck cancer: 2526.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 5.9" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1337.8;head and neck cancer: 928.9" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 6.8" "CAB006268, HPA011105, CAB040552" Enhanced Supported Cytosol "Secreted in other tissues" "No annotated function" NA Yes 29000000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 39 Cytosol "CAB006268: AB_425459, CAB040552: , HPA011105: AB_1844339" "unprognostic (5.70e-2)" "unprognostic (1.26e-1)" "unprognostic (8.37e-2)" "prognostic favorable (1.92e-4)" "unprognostic (1.26e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.68e-5)" "unprognostic (1.71e-2)" "unprognostic (2.99e-1)" "unprognostic (3.96e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.83e-1)" "prognostic unfavorable (7.45e-6)" "unprognostic (7.90e-3)" "unprognostic (3.25e-1)" "unprognostic (8.12e-2)" "unprognostic (2.06e-2)" SGSM3 "DJ1042K10.2, RabGAP-5, RABGAP5, RUSC3, RUTBC3" ENSG00000100359 "Small G protein signaling modulator 3" Q96HU1 22 40370591-40410289 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 112.6;Intestinal goblet cells: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048980 Approved Supported "Golgi apparatus" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Golgi apparatus" "HPA048980: AB_2680585" "unprognostic (4.63e-2)" "unprognostic (7.51e-3)" "unprognostic (3.02e-2)" "prognostic favorable (4.47e-5)" "unprognostic (1.81e-1)" "unprognostic (6.83e-3)" "unprognostic (5.70e-3)" "unprognostic (7.53e-2)" "unprognostic (3.57e-1)" "unprognostic (5.67e-2)" "unprognostic (1.71e-3)" "unprognostic (1.93e-1)" "unprognostic (2.97e-1)" "unprognostic (4.08e-3)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.98e-3)" SH2D3A NSP1 ENSG00000125731 "SH2 domain containing 3A" Q9BRG2 19 6752160-6767463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 62.7;Ionocytes: 65.9;Paneth cells: 67.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA035722, HPA064382" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA035722: AB_10670024, HPA064382: AB_2685251" "unprognostic (3.32e-2)" "unprognostic (5.48e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.09e-1)" "unprognostic (3.96e-1)" "unprognostic (2.60e-3)" "unprognostic (3.63e-1)" "unprognostic (8.41e-2)" "unprognostic (6.48e-3)" "prognostic unfavorable (6.21e-4)" "prognostic favorable (1.42e-4)" "unprognostic (7.31e-2)" "unprognostic (1.74e-1)" "unprognostic (1.32e-3)" "unprognostic (1.81e-3)" SH3BGRL2 ENSG00000198478 "SH3 domain binding glutamate rich protein like 2" Q9UJC5 6 79631329-79703655 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 157.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.8;Intestinal goblet cells: 99.8;Serous glandular cells: 123.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 50.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 11.0" "Lineage enriched" "Detected in many" 10 "granulocytes: 11.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 34.5" "Adipose visceral - Endothelial cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Testis - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047486 Approved Supported Nucleoplasm NA NA 2000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" Nucleoplasm "HPA047486: AB_2680065" "unprognostic (3.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.75e-2)" "unprognostic (2.28e-2)" "unprognostic (4.21e-1)" "unprognostic (7.77e-2)" "unprognostic (1.07e-1)" "unprognostic (1.60e-2)" "unprognostic (6.92e-2)" "unprognostic (6.53e-3)" "unprognostic (2.78e-1)" "unprognostic (7.94e-2)" "prognostic favorable (2.24e-4)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.33e-1)" SHH "HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS" ENSG00000164690 "Sonic hedgehog signaling molecule" Q15465 7 155799980-155812463 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein, Hydrolase, Protease, Transferase" "Disease variant, Holoprosencephaly, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 8.4;liver: 13.3;stomach 1: 10.2;urinary bladder: 15.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 10.8;Alveolar cells type 2: 9.9;Cholangiocytes: 15.3;Collecting duct cells: 7.8;Gastric mucus-secreting cells: 10.0;Glandular and luminal cells: 8.3;Hepatocytes: 17.7;Intestinal goblet cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 13.5" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Intracellular and membrane" "Developmental protein" NA NA 5500000 "Cluster 83: Liver - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "unprognostic (7.17e-2)" "unprognostic (7.68e-3)" "unprognostic (6.70e-2)" "prognostic favorable (8.62e-5)" "unprognostic (1.59e-1)" "unprognostic (2.50e-2)" "unprognostic (2.39e-3)" "unprognostic (1.82e-2)" "unprognostic (1.83e-1)" "unprognostic (2.16e-2)" "unprognostic (3.47e-1)" "unprognostic (1.56e-1)" "unprognostic (1.77e-3)" "unprognostic (2.86e-1)" "unprognostic (2.85e-1)" "unprognostic (3.43e-2)" "unprognostic (2.66e-2)" SHROOM3 "APXL3, KIAA1481, SHRM, ShrmL" ENSG00000138771 "Shroom family member 3" Q8TF72 4 76435229-76783253 "Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 296.9;Glandular and luminal cells: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047784 Enhanced NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA047784: AB_2680155" "unprognostic (1.96e-1)" "unprognostic (2.50e-1)" "unprognostic (1.57e-2)" "unprognostic (5.33e-2)" "unprognostic (1.61e-2)" "unprognostic (3.33e-2)" "unprognostic (7.96e-3)" "unprognostic (2.70e-2)" "unprognostic (1.92e-1)" "unprognostic (2.90e-1)" "unprognostic (1.45e-3)" "unprognostic (1.03e-1)" "prognostic favorable (1.64e-13)" "unprognostic (2.87e-2)" "unprognostic (2.25e-1)" "unprognostic (9.06e-2)" "unprognostic (1.87e-2)" SIRT7 ENSG00000187531 "Sirtuin 7" Q9NRC8 17 81911939-81921323 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 132.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027284, HPA028246, CAB037261, HPA053669" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" 2 Nucleoplasm "Nuclear speckles" "CAB037261: AB_1079989, HPA027284: , HPA028246: , HPA053669: AB_2682224" "unprognostic (8.15e-3)" "unprognostic (3.24e-2)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.46e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (1.97e-5)" "unprognostic (3.03e-1)" "unprognostic (2.10e-1)" "unprognostic (2.46e-2)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.69e-7)" "unprognostic (4.34e-3)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (2.16e-2)" SLC16A5 "MCT5, MCT6" ENSG00000170190 "Solute carrier family 16 member 5" O15375 17 75087727-75106162 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 90.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 45.2;Collecting duct cells: 83.6;Late spermatids: 40.8;Paneth cells: 33.6;Proximal enterocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.2;neutrophil: 35.1" "Group enriched" "Detected in all" 6 "granulocytes: 35.1;monocytes: 13.2" "Low cancer specificity" "Detected in many" "Liver - Vascular Endothelial cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 2 "unprognostic (1.86e-2)" "unprognostic (1.18e-1)" "unprognostic (1.98e-1)" "unprognostic (2.51e-2)" "unprognostic (2.90e-2)" "unprognostic (2.72e-1)" "unprognostic (6.30e-2)" "unprognostic (2.55e-1)" "unprognostic (1.61e-1)" "unprognostic (5.26e-2)" "unprognostic (8.43e-3)" "unprognostic (8.07e-2)" "unprognostic (9.63e-2)" "unprognostic (3.53e-3)" "unprognostic (5.44e-2)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" SLC17A9 "C20orf59, FLJ23412, VNUT" ENSG00000101194 "Solute carrier family 17 member 9" Q9BYT1 20 62952707-62969585 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Exocytosis, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 23.6;Hepatocytes: 32.3;Hofbauer cells: 16.2;Langerhans cells: 14.5;Plasma cells: 45.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 4.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 29.4" "Breast - Plasma cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA047470 Approved Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 77: Plasma cells - Protein processing" 6 Nucleoplasm "HPA047470: AB_2680060" "unprognostic (2.65e-3)" "unprognostic (2.13e-1)" "unprognostic (7.08e-2)" "unprognostic (1.97e-1)" "unprognostic (4.33e-3)" "unprognostic (5.33e-2)" "unprognostic (6.03e-2)" "unprognostic (6.84e-3)" "unprognostic (1.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (2.78e-15)" "unprognostic (6.06e-3)" "unprognostic (5.51e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" SLC22A18 "BWR1A, BWSCR1A, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5" ENSG00000110628 "Solute carrier family 22 member 18" Q96BI1 11 2899721-2925246 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.9;liver: 44.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 390.5;Late spermatids: 503.2;Paneth cells: 258.5;Proximal enterocytes: 763.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA067812, HPA071461" Enhanced NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 4 "HPA067812: AB_2685902, HPA071461: AB_2686401" "unprognostic (1.10e-1)" "unprognostic (1.14e-1)" "unprognostic (4.80e-1)" "unprognostic (7.75e-2)" "unprognostic (7.92e-3)" "unprognostic (2.67e-1)" "unprognostic (8.25e-2)" "unprognostic (4.21e-1)" "unprognostic (2.56e-2)" "unprognostic (3.48e-2)" "unprognostic (9.35e-2)" "unprognostic (8.60e-2)" "unprognostic (8.36e-2)" "unprognostic (9.51e-2)" "unprognostic (5.97e-3)" "unprognostic (1.55e-1)" "unprognostic (2.82e-1)" SLC22A23 "C6orf85, FLJ22174" ENSG00000137266 "Solute carrier family 22 member 23" A1A5C7 6 3268962-3457050 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 233.7;Oligodendrocytes: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014697 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 60: Prostate cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 3 "Nucleoplasm, Vesicles" Cytosol "HPA014697: AB_1844371" "unprognostic (4.58e-2)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.57e-4)" "unprognostic (5.16e-3)" "unprognostic (3.25e-3)" "unprognostic (1.40e-1)" "unprognostic (4.53e-3)" "unprognostic (9.74e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (8.91e-2)" "unprognostic (4.30e-1)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" SLC26A5 "DFNB61, PRES" ENSG00000170615 "Solute carrier family 26 member 5" P58743 7 103352730-103446207 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell shape, Hearing" "Motor protein" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 5.3;Excitatory neurons: 4.0;Gastric mucus-secreting cells: 7.1;Inhibitory neurons: 3.4;Lymphatic endothelial cells: 3.5;Microglial cells: 6.3;Oligodendrocytes: 3.9;Prostatic glandular cells: 4.5" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in some" "cerebellum: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "basal ganglia: 14.5" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "unprognostic (3.86e-2)" "unprognostic (5.13e-2)" "unprognostic (6.38e-3)" "unprognostic (2.76e-2)" "unprognostic (1.02e-2)" "unprognostic (5.09e-2)" "unprognostic (2.36e-1)" "unprognostic (3.56e-4)" "unprognostic (4.21e-3)" "unprognostic (8.92e-3)" "unprognostic (2.82e-1)" "unprognostic (2.97e-1)" "unprognostic (3.67e-5)" "unprognostic (3.05e-1)" "unprognostic (2.81e-1)" "unprognostic (2.94e-2)" "unprognostic (2.69e-3)" SLC35D2 "SQV7L, UGTrel8" ENSG00000130958 "Solute carrier family 35 member D2" Q76EJ3 9 96313444-96383711 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 109.0;Proximal enterocytes: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA064047 Approved Supported "Golgi apparatus" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" "Golgi apparatus" "HPA064047: AB_2685182" "unprognostic (3.67e-1)" "unprognostic (5.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.16e-2)" "unprognostic (3.17e-1)" "unprognostic (8.86e-3)" "unprognostic (4.25e-3)" "unprognostic (2.24e-2)" "unprognostic (4.12e-1)" "unprognostic (5.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-2)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (1.44e-1)" SLC37A1 SPX1 ENSG00000160190 "Solute carrier family 37 member 1" P57057 21 42496008-42581440 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 44.5" "Cell type enhanced" "Detected in many" "Early spermatids: 177.0;Late spermatids: 167.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030418, CAB034154" Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Breast glandular cells - Lactation" "CAB034154: AB_2190373, HPA030418: AB_10601602" "unprognostic (1.44e-2)" "unprognostic (2.93e-2)" "unprognostic (2.12e-1)" "prognostic favorable (9.22e-5)" "unprognostic (1.59e-2)" "unprognostic (1.42e-1)" "unprognostic (1.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.98e-1)" "unprognostic (7.99e-2)" "unprognostic (5.94e-2)" "unprognostic (1.86e-2)" "unprognostic (2.16e-1)" "unprognostic (4.08e-2)" "unprognostic (7.94e-2)" "prognostic favorable (3.43e-5)" "unprognostic (1.61e-2)" SLC39A11 C17orf26 ENSG00000133195 "Solute carrier family 39 member 11" Q8N1S5 17 72645949-73092712 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 194.8;Excitatory neurons: 104.1;Intestinal goblet cells: 82.2;Oligodendrocytes: 335.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Heart muscle - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021455 Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 48: Stomach - Proteolysis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" Nucleoplasm "HPA021455: AB_2670710" "unprognostic (2.29e-2)" "unprognostic (2.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.19e-1)" "unprognostic (1.61e-1)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-1)" "unprognostic (3.45e-3)" "unprognostic (2.30e-1)" "unprognostic (1.57e-3)" "unprognostic (5.26e-2)" "unprognostic (1.17e-1)" "unprognostic (4.96e-3)" "unprognostic (3.85e-2)" SLC44A2 CTL2 ENSG00000129353 "Solute carrier family 44 member 2" Q8IWA5 19 10602457-10644557 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 172.8;Extravillous trophoblasts: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003228, HPA070799" Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" "Vesicles, Cell Junctions" "HPA003228: AB_1080009, HPA070799: AB_2686314" "unprognostic (6.35e-3)" "unprognostic (5.75e-2)" "unprognostic (4.34e-1)" "unprognostic (3.06e-3)" "unprognostic (4.38e-2)" "unprognostic (8.41e-3)" "unprognostic (1.64e-1)" "unprognostic (2.52e-1)" "unprognostic (2.66e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (8.63e-2)" "prognostic favorable (1.71e-5)" "unprognostic (1.28e-1)" "unprognostic (1.67e-1)" "unprognostic (8.21e-3)" "unprognostic (3.61e-2)" SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 128.3;prostate: 80.5;stomach 1: 81.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 304.9;Club cells: 219.1;Distal enterocytes: 526.0;Gastric mucus-secreting cells: 189.2;Intestinal goblet cells: 253.6;Ionocytes: 213.9;Paneth cells: 184.9;Prostatic glandular cells: 320.8;Proximal enterocytes: 256.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 10.7;Gastric cancer: 10.1;prostate cancer: 27.9" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" "Symport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "prostate: 296.4" "Group enriched" "Detected in many" 6 "granulocytes: 113.6;Prostatic glandular cells: 431.1" "Cancer enriched" "Detected in all" 49 "prostate cancer: 539.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.6" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.6" "Cancer enriched" "Detected in all" 7 "prostate cancer: 115.8" "Breast - Breast myoepithelial cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 64: Neuronal - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 40: Prostatic glandular cells - Transcription" Vesicles Nucleoplasm "HPA019073: AB_1857177, HPA019075: AB_1857179" "unprognostic (1.80e-1)" "unprognostic (1.08e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.93e-2)" "unprognostic (2.36e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (3.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.33e-5)" SLC45A4 KIAA1126 ENSG00000022567 "Solute carrier family 45 member 4" Q5BKX6 8 141207166-141308305 "Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 38.9;Cone photoreceptor cells: 44.2;Gastric mucus-secreting cells: 41.3;Glandular and luminal cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "eosinophil: 8.3;neutrophil: 7.0" "Lineage enriched" "Detected in single" 22 "granulocytes: 8.3" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023154 Uncertain Approved "Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "Plasma membrane" "HPA023154: AB_2191204" "unprognostic (7.79e-3)" "unprognostic (1.06e-1)" "unprognostic (4.30e-2)" "unprognostic (1.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.96e-2)" "unprognostic (1.26e-1)" "unprognostic (4.49e-3)" "unprognostic (1.02e-1)" "unprognostic (5.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.84e-1)" "prognostic favorable (1.73e-6)" "unprognostic (8.79e-3)" "unprognostic (1.13e-1)" "unprognostic (1.77e-2)" "unprognostic (2.40e-2)" SLC50A1 "HsSWEET1, RAG1AP1, RP11-540D14.5, RZPDo834D038D, SCP, slv, SWEET1" ENSG00000169241 "Solute carrier family 50 member 1" Q9BRV3 1 155135344-155138857 "Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 149.0;Intestinal goblet cells: 178.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018095 Approved NA NA "Cluster 32: Basophils - Transcription" "Cluster 53: Non-specific - Glycosylation" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Breast glandular cells - Lactation" 3 "HPA018095: AB_1856048" "unprognostic (4.75e-2)" "unprognostic (1.21e-1)" "unprognostic (7.57e-2)" "unprognostic (2.24e-1)" "unprognostic (3.29e-1)" "unprognostic (9.30e-2)" "unprognostic (1.64e-3)" "unprognostic (1.95e-1)" "unprognostic (1.38e-1)" "unprognostic (5.51e-2)" "unprognostic (3.53e-3)" "unprognostic (2.59e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (4.36e-2)" "unprognostic (1.40e-1)" "unprognostic (3.50e-3)" "unprognostic (4.39e-2)" SLC5A5 NIS ENSG00000105641 "Solute carrier family 5 member 5" Q92911 19 17871945-17895174 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 138.0;salivary gland: 62.6;stomach 1: 57.3" "Cell type enriched" "Detected in some" 38 "Gastric mucus-secreting cells: 217.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 3.7" "Region enriched" "Detected in all" 15 "choroid plexus: 351.6" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022364, HPA049055" Enhanced NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" 2 "CAB022364: , HPA049055: AB_2680614" "unprognostic (2.72e-2)" "unprognostic (8.94e-2)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (4.02e-2)" "unprognostic (2.57e-1)" "unprognostic (1.94e-2)" "unprognostic (3.07e-1)" "unprognostic (2.01e-2)" "unprognostic (3.03e-1)" "unprognostic (3.93e-2)" "unprognostic (5.51e-8)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.54e-2)" "unprognostic (3.23e-1)" SLC6A14 ENSG00000268104 "Solute carrier family 6 member 14" Q9UN76 X 116436606-116461458 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 15.6;salivary gland: 20.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 193.3;Basal respiratory cells: 110.0;Club cells: 166.6;Ionocytes: 275.7;Mucus glandular cells: 107.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 10.1" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" HPA003193 Uncertain Approved Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" Vesicles "HPA003193: AB_2190122" "unprognostic (3.06e-2)" "unprognostic (3.55e-2)" "unprognostic (8.49e-2)" "unprognostic (1.00e-3)" "unprognostic (1.30e-3)" "unprognostic (1.49e-2)" "unprognostic (7.41e-3)" "unprognostic (3.67e-3)" "unprognostic (2.66e-1)" "unprognostic (1.83e-2)" "prognostic unfavorable (9.74e-4)" "unprognostic (1.34e-2)" "unprognostic (3.89e-2)" "unprognostic (2.08e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" SLC7A11 xCT ENSG00000151012 "Solute carrier family 7 member 11" Q9UPY5 4 138164097-138242349 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.1" "Cell type enhanced" "Detected in many" "Astrocytes: 349.6;dendritic cells: 75.1;Gastric mucus-secreting cells: 57.8;Langerhans cells: 69.4;Microglial cells: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 4 "Gallbladder cancer: 158.2" "Liver - Vascular Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064215 Approved Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Astrocytes - Unknown function" 4 Vesicles "HPA064215: AB_2685213" "unprognostic (3.55e-3)" "unprognostic (4.64e-3)" "unprognostic (2.43e-2)" "unprognostic (7.18e-3)" "unprognostic (2.59e-1)" "unprognostic (8.80e-3)" "unprognostic (2.07e-8)" "unprognostic (1.98e-2)" "unprognostic (1.09e-2)" "prognostic favorable (1.77e-4)" "unprognostic (1.90e-2)" "unprognostic (4.07e-2)" "unprognostic (2.22e-8)" "unprognostic (3.81e-2)" "unprognostic (3.76e-2)" "unprognostic (2.29e-2)" "unprognostic (1.54e-2)" SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 135.9;placenta: 99.0" "Group enriched" "Detected in many" 8 "Cytotrophoblasts: 1246.5;Syncytiotrophoblasts: 745.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" 35 "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: AB_10674985" "unprognostic (2.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.96e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.01e-1)" "unprognostic (1.63e-3)" "unprognostic (6.26e-2)" "unprognostic (7.48e-2)" "unprognostic (9.11e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.46e-1)" "prognostic favorable (2.24e-4)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-1)" SMIM22 CASIMO1 ENSG00000267795 "Small integral membrane protein 22" K7EJ46 16 4788397-4796491 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 188.3;pancreas: 149.9;salivary gland: 142.9;stomach 1: 196.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2064.5;Enteroendocrine cells: 620.1;Intestinal goblet cells: 1141.8;Paneth cells: 999.8;Proximal enterocytes: 1718.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 142.5;colorectal cancer: 173.2" "Breast - Breast glandular cells, Colon - Colon enterocytes, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077331 Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Nucleoplasm Cytosol "HPA077331: AB_2686834" "unprognostic (6.55e-2)" "unprognostic (4.12e-2)" "unprognostic (4.84e-2)" "unprognostic (3.69e-3)" "unprognostic (7.82e-2)" "unprognostic (3.84e-2)" "unprognostic (4.63e-2)" "unprognostic (2.67e-2)" "unprognostic (6.20e-2)" "unprognostic (3.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.60e-1)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (1.73e-3)" SMIM24 "C19orf77, HSPC323" ENSG00000095932 "Small integral membrane protein 24" O75264 19 3473986-3480525 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "epididymis: 1541.7;intestine: 731.3;kidney: 810.9" "Group enriched" "Detected in many" 11 "Proximal enterocytes: 4214.7;Proximal tubular cells: 1477.7" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.7;pancreatic cancer: 37.4;renal cancer: 78.4;stomach cancer: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Gastric cancer: 35.6;Leukemia: 96.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA045046, HPA056027" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm Cytosol "HPA045046: AB_10964444, HPA056027: AB_2683012" "unprognostic (2.18e-4)" "unprognostic (4.63e-1)" "unprognostic (5.68e-2)" "unprognostic (9.60e-2)" "unprognostic (1.93e-1)" "unprognostic (6.23e-2)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.64e-1)" "unprognostic (2.85e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.13e-10)" "unprognostic (1.68e-2)" "unprognostic (2.14e-1)" "unprognostic (8.36e-2)" "unprognostic (3.11e-2)" SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.8;lymphoid tissue: 50.7" "Cell type enhanced" "Detected in many" "dendritic cells: 221.5;Gastric mucus-secreting cells: 61.3;Horizontal cells: 71.8;Oocytes: 75.0;Proximal enterocytes: 102.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 139.0" "Lineage enriched" "Detected in many" 7 "dendritic cells: 139.0" "Cancer enhanced" "Detected in many" "Leukemia: 11.1;lymphoma: 12.1;Neuroblastoma: 11.2" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Peritubular cells" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 83.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 240.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 66.3;Early spermatids: 23.7;Gastric mucus-secreting cells: 61.9;Melanocytes: 42.9;Proximal tubular cells: 23.2" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Region enriched" "Detected in all" 27 "choroid plexus: 247.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" Other NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" SOX21 SOX25 ENSG00000125285 "SRY-box transcription factor 21" Q9Y651 13 94709622-94712545 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 12.4;esophagus: 10.0;skin 1: 15.5;stomach 1: 34.2" "Cell type enhanced" "Detected in some" "Astrocytes: 23.2;Basal squamous epithelial cells: 21.1;Gastric mucus-secreting cells: 61.3;Oligodendrocyte precursor cells: 16.0;Squamous epithelial cells: 61.7" "Cancer enhanced" "Detected in many" "glioma: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 13.8" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048337, HPA064084" Approved Approved Nucleoplasm NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Squamous epithelial cells - Keratinization" Nucleoplasm "HPA048337: AB_2732547, HPA064084: AB_2685187" "unprognostic (3.33e-1)" "prognostic favorable (7.60e-4)" "unprognostic (7.96e-2)" "prognostic favorable (8.79e-5)" "unprognostic (1.54e-2)" "unprognostic (3.87e-1)" "unprognostic (9.02e-2)" "unprognostic (2.11e-1)" "unprognostic (1.50e-1)" "unprognostic (2.90e-2)" "unprognostic (1.93e-1)" "unprognostic (6.05e-2)" "unprognostic (1.11e-1)" "unprognostic (3.51e-1)" "unprognostic (2.25e-1)" "unprognostic (1.35e-1)" SPACA4 SAMP14 ENSG00000177202 "Sperm acrosome associated 4" Q8TDM5 19 48606742-48607714 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "testis: 114.5" "Group enriched" "Detected in some" 93 "Early spermatids: 1020.1;Late spermatids: 363.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.3" "Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041927, HPA061302" Enhanced NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" "HPA041927: AB_10794162, HPA061302: AB_2684475" "unprognostic (2.48e-2)" "unprognostic (6.37e-4)" "unprognostic (6.59e-2)" "unprognostic (4.52e-2)" "unprognostic (2.09e-3)" "unprognostic (9.43e-6)" "unprognostic (6.67e-3)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (2.78e-1)" "unprognostic (3.43e-1)" "unprognostic (2.88e-1)" "unprognostic (4.47e-1)" "unprognostic (2.01e-2)" SPINK13 "HESPINTOR, LiESP6, MGC149260, SPINK5L3" ENSG00000214510 "Serine peptidase inhibitor Kazal type 13" Q1W4C9 5 148268180-148286255 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "epididymis: 320.7" "Group enriched" "Detected in some" 23 "Basal prostatic cells: 90.8;Leydig cells: 39.8;Peritubular cells: 26.7" "Cancer enhanced" "Detected in some" "renal cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "cervical cancer: 97.7" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036456 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" "Enzyme inhibitor" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "Plasma membrane" Nucleoplasm "HPA036456: AB_10673496" "unprognostic (5.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.22e-1)" "unprognostic (1.41e-2)" "unprognostic (6.43e-3)" "unprognostic (1.25e-3)" "unprognostic (5.01e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (4.03e-10)" "unprognostic (4.31e-2)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (2.95e-2)" SPINK7 "ECG2, ECRG2" ENSG00000145879 "Serine peptidase inhibitor Kazal type 7" P58062 5 148312419-148315922 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 249.8;esophagus: 603.0;vagina: 595.4" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 259.8" "Group enriched" "Detected in many" 6 "cervical cancer: 4.5;head and neck cancer: 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 4.4;Esophageal cancer: 3.7;head and neck cancer: 10.1;lung cancer: 4.7" "Skin - Hair cortex cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036294 Enhanced "Secreted in other tissues" "Enzyme inhibitor" NA NA 230000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 59: Suprabasal keratinocytes - Cornification" 6 "HPA036294: AB_10671243" "unprognostic (2.82e-1)" "unprognostic (8.99e-3)" "unprognostic (8.52e-3)" "unprognostic (1.81e-1)" "unprognostic (1.12e-2)" "unprognostic (3.37e-2)" "unprognostic (9.10e-2)" "unprognostic (1.49e-1)" "unprognostic (6.86e-2)" "unprognostic (7.24e-2)" "unprognostic (4.22e-2)" SPINT1 "HAI, HAI-1, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 248.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1211.1;Ductal cells: 415.0;Proximal enterocytes: 467.2;Syncytiotrophoblasts: 1698.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" "Enzyme inhibitor" NA NA 7400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" SPINT2 "HAI-2, HAI2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1385.4;Syncytiotrophoblasts: 1381.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" SPIRE2 "KIAA1832, spir-2" ENSG00000204991 "Spire type actin nucleation factor 2" Q8WWL2 16 89818179-89871319 "Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.2;pituitary gland: 20.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 43.3;Gastric mucus-secreting cells: 43.6;Intestinal goblet cells: 47.9;Paneth cells: 32.7;Syncytiotrophoblasts: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041413, HPA049415" Uncertain Approved "Nucleoplasm,Vesicles,Intermediate filaments" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 80: Non-specific - Endocytosis" "Cluster 37: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm "Vesicles, Intermediate filaments" "HPA041413: AB_2677464, HPA049415: AB_2680755" "unprognostic (2.92e-1)" "unprognostic (1.39e-1)" "unprognostic (6.07e-3)" "unprognostic (6.96e-2)" "unprognostic (7.40e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (9.77e-5)" "unprognostic (2.10e-1)" "unprognostic (7.75e-2)" "unprognostic (5.34e-2)" "unprognostic (1.08e-2)" "unprognostic (6.95e-3)" "unprognostic (7.21e-3)" "unprognostic (6.65e-2)" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.59e-2)" SPTSSB "ADMP, C3orf57, ssSPTb" ENSG00000196542 "Serine palmitoyltransferase small subunit B" Q8NFR3 3 161344798-161372880 "Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.7;stomach 1: 69.1;urinary bladder: 64.6" "Cell type enhanced" "Detected in many" "Club cells: 48.2;Excitatory neurons: 27.6;Gastric mucus-secreting cells: 33.6;Melanocytes: 55.0;Prostatic glandular cells: 73.1;Suprabasal keratinocytes: 28.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 24.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 13 "NK-cell: 329.8" "Lineage enriched" "Detected in many" 13 "NK-cells: 329.8" "Group enriched" "Detected in many" 4 "breast cancer: 142.2;Gallbladder cancer: 77.8" "Pancreas - Alpha cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 1 "unprognostic (2.09e-1)" "unprognostic (4.19e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" "unprognostic (1.34e-2)" "unprognostic (4.15e-2)" "unprognostic (3.18e-2)" "unprognostic (1.98e-1)" "unprognostic (5.10e-2)" "unprognostic (6.37e-3)" "unprognostic (2.72e-1)" "unprognostic (4.08e-2)" "unprognostic (5.37e-4)" "unprognostic (8.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.22e-2)" "unprognostic (9.51e-3)" ST14 "CAP3, HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 140.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 375.6;Intestinal goblet cells: 175.1;Paneth cells: 164.2;Proximal enterocytes: 201.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 19.4" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Colon enterocytes, Heart muscle - Macrophages, Pancreas - Ductal cells, Skeletal muscle - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "Nucleoplasm, Vesicles" "HPA047014: AB_2679902, HPA056258: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" STAP2 "BKS, STAP-2" ENSG00000178078 "Signal transducing adaptor family member 2" Q9UGK3 19 4324043-4342786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 166.6;Distal enterocytes: 335.5;Paneth cells: 316.8;Proximal enterocytes: 434.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 8.0" "Group enriched" "Detected in many" 6 "dendritic cells: 2.2;NK-cells: 8.0;T-cells: 2.5" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Pancreas - Ductal cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Region enriched" "Detected in many" 13 "cerebellum: 20.5" "Low region specificity" "Detected in some" "HPA002375, HPA027761" Approved NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 9 "HPA002375: AB_1078285, HPA027761: AB_1845364" "unprognostic (1.42e-1)" "prognostic favorable (2.76e-4)" "unprognostic (3.52e-1)" "prognostic favorable (3.03e-5)" "unprognostic (4.35e-2)" "unprognostic (9.35e-3)" "unprognostic (4.52e-1)" "unprognostic (7.81e-2)" "unprognostic (3.43e-1)" "unprognostic (2.00e-2)" "unprognostic (1.93e-2)" "unprognostic (9.05e-2)" "unprognostic (1.43e-3)" "unprognostic (1.38e-2)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "prognostic favorable (4.13e-4)" STXBP2 "Hunc18b, MUNC18-2, Unc18-2, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636772-7647873 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 153.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 365.0;monocytes: 867.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 837.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 870000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 Cytosol "HPA015564: AB_1857626, HPA063868: AB_2685136" "unprognostic (1.20e-2)" "unprognostic (6.17e-3)" "unprognostic (2.85e-2)" "prognostic favorable (2.29e-4)" "unprognostic (2.54e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (4.65e-4)" "unprognostic (4.22e-3)" "unprognostic (2.35e-1)" "unprognostic (6.25e-2)" "unprognostic (1.79e-1)" "unprognostic (4.99e-2)" "unprognostic (1.51e-1)" "unprognostic (4.62e-2)" "unprognostic (2.85e-1)" "prognostic favorable (7.68e-4)" "prognostic favorable (5.13e-6)" STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618923-10674318 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.5;stomach 1: 17.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 21.5;Excitatory neurons: 19.9;Gastric mucus-secreting cells: 15.9;Intestinal goblet cells: 14.3;Prostatic glandular cells: 20.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" 2 "Plasma membrane" Nucleoplasm "HPA040468: AB_2676998, HPA048569: AB_2680446" "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" SULT1B1 ST1B2 ENSG00000173597 "Sulfotransferase family 1B member 1" O43704 4 69721167-69787961 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 96.3;stomach 1: 43.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 295.5;Enteroendocrine cells: 53.8;Gastric mucus-secreting cells: 56.0;Paneth cells: 112.2;Proximal enterocytes: 223.7" "Group enriched" "Detected in some" 11 "colorectal cancer: 7.6;liver cancer: 2.6;pancreatic cancer: 5.5;stomach cancer: 5.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 10.6;neutrophil: 32.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 32.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Colon - Colon enterocytes, Prostate - Macrophages, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002107 Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 9: Non-specific - Receptor signaling" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 5: Enterocytes - Absorption" 7 "Golgi apparatus" Nucleoplasm "HPA002107: AB_2666542" "unprognostic (9.58e-2)" "unprognostic (4.05e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (2.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "unprognostic (4.77e-2)" "unprognostic (5.14e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-1)" "unprognostic (1.15e-3)" "unprognostic (1.89e-1)" "unprognostic (1.06e-2)" "unprognostic (6.93e-2)" "unprognostic (5.46e-2)" SULT1C2 "ST1C1, SULT1C1" ENSG00000198203 "Sulfotransferase family 1C member 2" O00338 2 108288639-108309915 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 68.4;stomach 1: 159.3" "Cell type enriched" "Detected in many" 8 "Gastric mucus-secreting cells: 517.6" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Region enriched" "Detected in many" 6 "choroid plexus: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 49.6;liver cancer: 20.1" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007190 Approved NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 46: Gastric mucus-secreting cells - Digestion" 1 "HPA007190: AB_1857647" "unprognostic (3.31e-2)" "unprognostic (1.63e-2)" "unprognostic (3.41e-1)" "unprognostic (2.14e-2)" "unprognostic (2.55e-1)" "unprognostic (3.33e-2)" "unprognostic (1.17e-3)" "unprognostic (3.61e-2)" "unprognostic (3.78e-1)" "unprognostic (3.62e-2)" "unprognostic (8.74e-2)" "unprognostic (2.76e-1)" "unprognostic (3.19e-2)" "unprognostic (9.27e-2)" "unprognostic (6.28e-2)" "unprognostic (4.63e-2)" "unprognostic (9.96e-5)" SYT8 DKFZp434K0322 ENSG00000149043 "Synaptotagmin 8" Q8NBV8 11 1828307-1837521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 28.4;skin 1: 63.4;urinary bladder: 39.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 125.9;Basal squamous epithelial cells: 300.7;Breast myoepithelial cells: 256.7;Cholangiocytes: 192.7;Ciliated cells: 97.8;Extravillous trophoblasts: 241.1;Squamous epithelial cells: 112.2" "Group enriched" "Detected in many" 5 "cervical cancer: 10.5;pancreatic cancer: 21.7;urothelial cancer: 33.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 15.3;pancreatic cancer: 8.2" "Liver - Cholangiocyte, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047239, HPA052700" Uncertain Approved "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA047239: , HPA052700: AB_2681920" "unprognostic (1.66e-3)" "unprognostic (2.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.14e-1)" "unprognostic (6.31e-2)" "unprognostic (2.06e-1)" "unprognostic (3.10e-2)" "unprognostic (1.36e-2)" "unprognostic (1.02e-1)" "unprognostic (8.25e-2)" "unprognostic (7.09e-2)" "unprognostic (2.48e-1)" "unprognostic (2.33e-6)" "unprognostic (2.87e-2)" "unprognostic (1.75e-1)" "unprognostic (5.52e-2)" "unprognostic (2.77e-2)" SYTL2 "CHR11SYT, exophilin-4, FLJ20163, FLJ21219, KIAA1597, MGC102768, PPP1R151, SGA72M, SLP2" ENSG00000137501 "Synaptotagmin like 2" Q9HCH5 11 85694224-85811159 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 70.7;stomach 1: 122.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 100.5;Gastric mucus-secreting cells: 365.5;Intestinal goblet cells: 245.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 13.9;MAIT T-cell: 23.8" "Lineage enriched" "Detected in many" 6 "T-cells: 23.8" "Cancer enhanced" "Detected in many" "Kidney cancer: 85.8" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039651 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Nucleoplasm, Golgi apparatus" "Plasma membrane" "HPA039651: AB_10795153" "unprognostic (8.07e-3)" "unprognostic (6.72e-3)" "prognostic favorable (2.67e-4)" "unprognostic (9.34e-4)" "unprognostic (6.60e-3)" "unprognostic (2.19e-4)" "unprognostic (2.24e-2)" "unprognostic (5.37e-2)" "unprognostic (5.56e-2)" "unprognostic (5.45e-2)" "unprognostic (1.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.85e-2)" "unprognostic (4.03e-1)" "unprognostic (1.87e-2)" "unprognostic (9.72e-2)" "prognostic favorable (9.07e-4)" TC2N "C14orf47, C2CD1, FLJ36557, MTAC2D1, Tac2-N" ENSG00000165929 "Tandem C2 domains, nuclear" Q8N9U0 14 91779746-91867536 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 100.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 245.6;Mucus glandular cells: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 84.7" "Group enriched" "Detected in many" 47 "NK-cells: 39.3;T-cells: 84.7" "Cancer enhanced" "Detected in many" "breast cancer: 24.4" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA027549 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Nucleoplasm, Nuclear bodies" "HPA027549: AB_10603346" "unprognostic (5.36e-2)" "unprognostic (1.95e-1)" "unprognostic (4.70e-2)" "unprognostic (1.51e-1)" "unprognostic (7.17e-3)" "unprognostic (3.34e-2)" "unprognostic (2.38e-1)" "unprognostic (2.78e-2)" "unprognostic (3.44e-1)" "unprognostic (8.56e-2)" "prognostic unfavorable (9.86e-4)" "unprognostic (3.00e-1)" "prognostic favorable (4.13e-5)" "unprognostic (6.82e-2)" "unprognostic (1.65e-1)" "unprognostic (3.01e-1)" "unprognostic (1.09e-2)" TESC "CHP3, FLJ20607, TSC" ENSG00000088992 Tescalcin Q96BS2 12 117038923-117099479 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 320.1" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 259.2;Gastric mucus-secreting cells: 303.6;Late spermatids: 316.9;monocytes: 237.6;Oocytes: 233.8;Serous glandular cells: 553.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 262.4" "Lineage enriched" "Detected in all" 5 "monocytes: 262.4" "Cancer enhanced" "Detected in many" "Bile duct cancer: 88.8;Gastric cancer: 89.6;Leukemia: 85.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053200 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" 3 Nucleoplasm Cytosol "HPA053200: AB_2682079" "unprognostic (4.53e-3)" "unprognostic (5.98e-2)" "unprognostic (6.50e-2)" "unprognostic (2.23e-3)" "unprognostic (6.31e-2)" "unprognostic (2.05e-3)" "unprognostic (4.98e-3)" "unprognostic (3.35e-1)" "unprognostic (4.35e-1)" "unprognostic (1.62e-1)" "unprognostic (4.37e-2)" "unprognostic (7.43e-2)" "unprognostic (1.69e-2)" "unprognostic (8.65e-2)" "unprognostic (2.57e-1)" "unprognostic (1.56e-2)" "unprognostic (5.67e-3)" TEX35 "C1orf49, DKFZP564J047, TSC24" ENSG00000240021 "Testis expressed 35" Q5T0J7 1 178513109-178548602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 61 "testis: 114.7" "Group enriched" "Detected in some" 192 "Early spermatids: 836.0;Late spermatids: 2310.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA039190 Approved NA NA "Cluster 10: Testis - Spermatid development" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 11: Late spermatids - Unknown function" "HPA039190: AB_10794425" "unprognostic (2.20e-1)" "unprognostic (1.77e-2)" "unprognostic (1.26e-1)" "unprognostic (1.89e-2)" "unprognostic (8.92e-3)" "unprognostic (1.08e-2)" "unprognostic (7.04e-2)" "unprognostic (9.60e-2)" "unprognostic (1.21e-1)" "unprognostic (2.51e-3)" "unprognostic (2.01e-2)" "unprognostic (1.92e-1)" "unprognostic (5.23e-1)" "unprognostic (5.41e-2)" TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.7" "Cell type enhanced" "Detected in many" "Ductal cells: 31.3;Early spermatids: 30.9;Oligodendrocyte precursor cells: 55.7;Oligodendrocytes: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.4;eosinophil: 23.9;neutrophil: 24.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 24.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 179.0" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042297 Approved Approved Vesicles "Secreted to blood" "Growth factor" No No 57900 "Cluster 21: Neutrophils - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 3 Vesicles "HPA042297: AB_10793878" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (3.57e-3)" "unprognostic (6.39e-2)" "unprognostic (1.41e-1)" "unprognostic (8.49e-3)" "unprognostic (1.52e-1)" "unprognostic (3.00e-3)" "unprognostic (6.69e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (7.74e-2)" "unprognostic (3.70e-2)" "unprognostic (1.60e-1)" "unprognostic (9.21e-2)" "prognostic favorable (1.52e-4)" "unprognostic (9.19e-2)" TJP3 ZO-3 ENSG00000105289 "Tight junction protein 3" O95049 19 3708362-3750813 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8;stomach 1: 26.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 198.8;Early spermatids: 585.1;Paneth cells: 108.7;Proximal enterocytes: 127.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "choroid plexus: 16.2" "Group enriched" "Detected in many" 5 "gdT-cell: 1.2;MAIT T-cell: 3.9;memory CD4 T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD4 T-cell: 3.3;naive CD8 T-cell: 1.2;T-reg: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB013244, HPA046863, HPA053337" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" 1 "Nucleoplasm, Cell Junctions" "Plasma membrane" "CAB013244: AB_2533257, HPA046863: AB_2679845, HPA053337: AB_2682118" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.83e-6)" "unprognostic (2.78e-1)" "prognostic favorable (9.52e-4)" "unprognostic (1.30e-1)" "unprognostic (1.25e-1)" "unprognostic (2.52e-1)" "unprognostic (6.52e-2)" "unprognostic (2.15e-2)" "unprognostic (1.78e-1)" "prognostic favorable (9.36e-8)" "unprognostic (8.58e-3)" "unprognostic (5.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.62e-3)" TM4SF5 ENSG00000142484 "Transmembrane 4 L six family member 5" O14894 17 4771884-4783213 "Predicted membrane proteins, Transporters" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 169.5;liver: 199.4" "Group enriched" "Detected in some" 5 "Enteroendocrine cells: 199.9;Hepatocytes: 237.5;Intestinal goblet cells: 192.6;Paneth cells: 251.0;Proximal enterocytes: 575.3" "Cancer enriched" "Detected in many" 9 "liver cancer: 219.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 16.0;Gastric cancer: 17.2;liver cancer: 34.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA055674 Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane, Cell Junctions" Nucleoplasm "HPA055674: " "unprognostic (1.81e-1)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (4.44e-2)" "unprognostic (9.33e-2)" "unprognostic (3.57e-2)" "unprognostic (1.95e-1)" "unprognostic (5.21e-3)" TMC4 ENSG00000167608 "Transmembrane channel like 4" 19 54160108-54173250 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 44.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 114.5;Distal enterocytes: 144.1;Proximal enterocytes: 214.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA048635 Approved Approved Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" Vesicles "HPA048635: AB_2680470" "unprognostic (7.55e-2)" "unprognostic (1.66e-1)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.82e-2)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-3)" "unprognostic (7.59e-2)" "unprognostic (3.09e-1)" "prognostic favorable (1.54e-8)" "unprognostic (6.70e-2)" "unprognostic (2.48e-1)" "unprognostic (8.94e-2)" "unprognostic (1.79e-2)" TMEM134 FLJ21749 ENSG00000172663 "Transmembrane protein 134" Q9H6X4 11 67461710-67469272 "Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043744 Approved Supported Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 7: Non-specific - Ribosome" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" Cytosol "HPA043744: AB_10794773" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (1.22e-1)" "unprognostic (4.67e-2)" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (7.22e-2)" "unprognostic (3.85e-1)" "unprognostic (1.39e-2)" "unprognostic (4.30e-2)" "unprognostic (3.48e-1)" "unprognostic (1.75e-1)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-2)" "unprognostic (4.43e-3)" TMEM163 "DKFZP566N034, SV31" ENSG00000152128 "Transmembrane protein 163" Q8TC26 2 134455759-134719000 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.4;pancreas: 27.0" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 54.1;Excitatory neurons: 60.1;Oligodendrocyte precursor cells: 206.1;Oocytes: 193.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 16.3" "Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007224 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA007224: AB_2667780" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (7.25e-3)" "unprognostic (3.18e-1)" "unprognostic (1.47e-1)" "unprognostic (2.25e-1)" "unprognostic (6.08e-3)" "prognostic favorable (7.94e-4)" "unprognostic (9.05e-2)" "unprognostic (9.62e-2)" "unprognostic (6.02e-2)" "unprognostic (2.04e-1)" "unprognostic (2.60e-2)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" "unprognostic (6.75e-3)" "prognostic favorable (3.15e-4)" TMEM38A "MGC3169, TRIC-A" ENSG00000072954 "Transmembrane protein 38A" Q9H6F2 19 16661139-16690023 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 559.8;tongue: 249.5" "Group enriched" "Detected in many" 6 "Cone photoreceptor cells: 132.5;Skeletal myocytes: 259.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 36.7;eosinophil: 12.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 36.7" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048100, HPA050463" Enhanced Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 2: Skeletal myocytes - Muscle contraction" Nucleoplasm "HPA048100: , HPA050463: AB_2681137" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-3)" "unprognostic (3.87e-1)" "unprognostic (2.99e-1)" "unprognostic (3.49e-1)" "prognostic favorable (2.78e-5)" "unprognostic (2.94e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (1.06e-1)" "unprognostic (2.68e-1)" "prognostic favorable (2.99e-10)" "unprognostic (1.93e-1)" "unprognostic (1.80e-1)" "unprognostic (4.50e-3)" "unprognostic (1.96e-2)" TMEM45B "BC016153, FLJ40787" ENSG00000151715 "Transmembrane protein 45B" Q96B21 11 129815848-129860003 "Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 64.6;intestine: 132.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 79.7;Club cells: 79.2;Distal enterocytes: 262.3;Enteroendocrine cells: 79.6;Ionocytes: 92.4;Paneth cells: 125.7;Proximal enterocytes: 291.2;Undifferentiated cells: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 3.6;neutrophil: 11.8" "Group enriched" "Detected in many" 14 "granulocytes: 11.8;T-cells: 3.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 56.4;prostate cancer: 85.3" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015474, HPA015878" Approved Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 31 Nucleoplasm "HPA015474: , HPA015878: AB_2205046" "unprognostic (4.92e-3)" "unprognostic (7.94e-2)" "unprognostic (5.98e-2)" "unprognostic (1.81e-1)" "unprognostic (5.44e-3)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (6.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.02e-3)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (1.42e-2)" "unprognostic (2.24e-1)" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" TMEM54 "BCLP, CAC-1" ENSG00000121900 "Transmembrane protein 54" Q969K7 1 32894594-32901438 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 260.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1854.5;Paneth cells: 671.1;Proximal enterocytes: 472.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060864, HPA061992" Approved Approved Vesicles NA NA "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 19 Vesicles "HPA060864: , HPA061992: AB_2684652" "unprognostic (2.67e-1)" "unprognostic (2.57e-2)" "unprognostic (2.55e-1)" "unprognostic (4.98e-2)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.42e-2)" "unprognostic (3.48e-2)" "unprognostic (9.43e-2)" "unprognostic (6.82e-3)" "unprognostic (2.13e-2)" "unprognostic (9.06e-2)" "unprognostic (3.12e-2)" "unprognostic (3.40e-2)" TMEM63B "C6orf110, dJ421H19.2, DKFZp434P0531" ENSG00000137216 "Transmembrane protein 63B" Q5T3F8 6 44126914-44155519 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 77.6;Late spermatids: 107.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029249, HPA029250, HPA029251" Uncertain Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 21: Testis - Unknown function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 72: Alveolar cells - Lung function" "Plasma membrane, Actin filaments" "HPA029249: AB_2672965, HPA029250: AB_2672966, HPA029251: AB_2672967" "unprognostic (8.83e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-3)" "unprognostic (3.61e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.97e-3)" "unprognostic (1.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-1)" "unprognostic (8.60e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.67e-2)" "unprognostic (6.12e-3)" "unprognostic (3.15e-1)" TMEM82 ENSG00000162460 "Transmembrane protein 82" A0PJX8 1 15742499-15747982 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 23.7;kidney: 11.2;liver: 51.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 68.8;Hepatocytes: 44.8;Paneth cells: 49.0;Proximal enterocytes: 183.5;Proximal tubular cells: 42.9" "Cancer enhanced" "Detected in some" "liver cancer: 10.2;renal cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA060282 Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" Nucleoplasm Cytosol "HPA060282: AB_2684241" "unprognostic (2.46e-2)" "unprognostic (7.96e-2)" "unprognostic (4.88e-2)" "unprognostic (1.40e-2)" "unprognostic (6.45e-2)" "unprognostic (6.90e-2)" "unprognostic (4.80e-2)" "prognostic favorable (3.80e-7)" "unprognostic (1.41e-1)" "unprognostic (5.80e-2)" "unprognostic (4.75e-2)" "unprognostic (1.09e-1)" TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 271.1;stomach 1: 142.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 264.9;Gastric mucus-secreting cells: 171.0;Paneth cells: 147.3;Prostatic glandular cells: 371.1;Proximal enterocytes: 168.4" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 267.6" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 2 "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" TMPRSS4 "CAP2, MT-SP2, TMPRSS3" ENSG00000137648 "Transmembrane serine protease 4" Q9NRS4 11 118077012-118121890 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 105.7;intestine: 42.1;urinary bladder: 71.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 99.4;Basal squamous epithelial cells: 61.8;Club cells: 111.2;Distal enterocytes: 143.5;Glandular and luminal cells: 64.6;Ionocytes: 135.5;Squamous epithelial cells: 126.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 2.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 70.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA006238 Uncertain "Secreted in other tissues" Enzyme NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 10 "HPA006238: AB_1080316" "unprognostic (1.48e-1)" "unprognostic (3.27e-2)" "unprognostic (1.19e-2)" "unprognostic (1.23e-1)" "unprognostic (5.23e-2)" "unprognostic (5.50e-2)" "unprognostic (8.17e-3)" "unprognostic (1.95e-2)" "unprognostic (2.41e-1)" "unprognostic (9.62e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (2.87e-3)" "unprognostic (2.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-2)" "unprognostic (9.96e-3)" TOR4A "C9orf167, FLJ20245" ENSG00000198113 "Torsin family 4 member A" Q9NXH8 9 137277726-137282641 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.2;monocytes: 34.7;Undifferentiated cells: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044913 Enhanced Approved Nucleoplasm NA NA 260000 "Cluster 22: Eosinophils - Transcription" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm "HPA044913: AB_10965030" "unprognostic (1.95e-1)" "unprognostic (1.51e-2)" "prognostic unfavorable (6.48e-4)" "unprognostic (1.99e-1)" "unprognostic (3.56e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (5.42e-3)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (1.11e-2)" "unprognostic (2.24e-1)" "unprognostic (5.20e-2)" "unprognostic (2.00e-3)" "unprognostic (4.39e-3)" "unprognostic (7.93e-3)" "unprognostic (2.56e-1)" TRAF4 "CART1, MLN62, RNF83" ENSG00000076604 "TNF receptor associated factor 4" Q9BUZ4 17 28744011-28750956 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Immunity, Innate immunity, Ubl conjugation pathway" "Developmental protein, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 43.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 43.0" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009055, HPA021904, HPA052377" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Stomach - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" 73 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "CAB009055: AB_2209701, HPA021904: , HPA052377: AB_2681804" "unprognostic (1.77e-1)" "unprognostic (9.05e-2)" "unprognostic (1.31e-2)" "unprognostic (2.51e-3)" "unprognostic (1.76e-1)" "unprognostic (7.38e-3)" "unprognostic (1.09e-2)" "unprognostic (1.24e-1)" "unprognostic (1.09e-2)" "unprognostic (2.33e-1)" "unprognostic (7.13e-2)" "unprognostic (7.55e-2)" "unprognostic (1.74e-3)" "unprognostic (6.98e-2)" "unprognostic (9.26e-2)" "unprognostic (2.77e-2)" "unprognostic (5.58e-3)" TRAK1 "KIAA1042, MILT1, OIP106" ENSG00000182606 "Trafficking kinesin protein 1" Q9UPV9 3 42013802-42225890 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 163.0;skeletal muscle: 253.2;tongue: 194.7" "Cell type enhanced" "Detected in many" "Astrocytes: 164.1;Cardiomyocytes: 263.2;Rod photoreceptor cells: 138.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005853, HPA011367" Approved Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 3: Non-specific - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Cardiomyocytes - Muscle contraction" 3 "Endoplasmic reticulum" Nucleoplasm "HPA005853: AB_1854778, HPA011367: AB_2668495" "unprognostic (5.55e-2)" "unprognostic (1.38e-2)" "unprognostic (5.49e-2)" "unprognostic (2.52e-2)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.80e-2)" "unprognostic (1.95e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" "unprognostic (3.01e-2)" "unprognostic (3.56e-3)" "prognostic favorable (4.84e-8)" "unprognostic (3.65e-2)" "unprognostic (1.70e-1)" "unprognostic (1.00e-2)" "unprognostic (4.61e-3)" TRIM16 EBBP ENSG00000221926 "Tripartite motif containing 16" O95361 17 15627960-15684311 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 141.8" "Cell type enhanced" "Detected in many" "Ionocytes: 69.6;Squamous epithelial cells: 103.2;Suprabasal keratinocytes: 140.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "T-reg: 44.9" "Lineage enriched" "Detected in many" 11 "T-cells: 44.9" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023623, HPA066431" Uncertain Supported "Plasma membrane,Cytosol" NA NA 19000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Respiratory epithelial cells - Unknown function" 2 Cytosol "Plasma membrane" "HPA023623: AB_1858273, HPA066431: AB_2685668" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (9.61e-2)" "unprognostic (1.31e-2)" "unprognostic (6.19e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.94e-3)" "unprognostic (3.75e-2)" "unprognostic (4.65e-1)" "unprognostic (3.31e-3)" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.08e-1)" "unprognostic (8.48e-2)" "unprognostic (9.21e-3)" "prognostic unfavorable (6.71e-4)" TRIM31 "C6orf13, HCG1, HCGI, RNF" ENSG00000204616 "Tripartite motif containing 31" Q9BZY9 6 30102897-30113090 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Inflammatory response, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 21.5;stomach 1: 5.8;urinary bladder: 8.3" "Group enriched" "Detected in some" 8 "Club cells: 98.9;Distal enterocytes: 206.8;Gastric mucus-secreting cells: 73.1;Intestinal goblet cells: 66.9;Paneth cells: 64.6;Proximal enterocytes: 188.1" "Group enriched" "Detected in many" 5 "cervical cancer: 6.7;colorectal cancer: 25.8;pancreatic cancer: 11.4;stomach cancer: 19.8;urothelial cancer: 12.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 6.7;Bladder cancer: 9.8" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074175 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 3 "HPA074175: " "unprognostic (1.37e-1)" "unprognostic (7.78e-3)" "unprognostic (1.83e-1)" "unprognostic (7.05e-3)" "unprognostic (1.75e-1)" "unprognostic (9.37e-2)" "unprognostic (6.13e-2)" "unprognostic (1.32e-1)" "unprognostic (2.05e-1)" "unprognostic (1.11e-2)" "unprognostic (1.97e-2)" "unprognostic (1.92e-1)" "unprognostic (1.43e-3)" "unprognostic (5.84e-3)" "unprognostic (6.20e-2)" "unprognostic (1.60e-1)" "unprognostic (2.50e-3)" TRIM40 RNF35 ENSG00000204614 "Tripartite motif containing 40" Q6P9F5 6 30136124-30148735 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 2.9;liver: 1.5;testis: 1.4" "Group enriched" "Detected in some" 6 "Distal enterocytes: 6.2;Intestinal goblet cells: 3.2;Paneth cells: 2.6;Proximal enterocytes: 4.7;Spermatocytes: 2.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.7;stomach cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 18 "thalamus: 3.1" "Low region specificity" "Detected in all" HPA043818 Uncertain Approved Cytosol NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" Cytosol "HPA043818: AB_10963090" "unprognostic (2.88e-1)" "unprognostic (5.20e-2)" "unprognostic (4.11e-1)" "unprognostic (1.13e-1)" "unprognostic (1.77e-1)" "unprognostic (4.84e-2)" TRNP1 "C1orf225, TRNP" ENSG00000253368 "TMF1 regulated nuclear protein 1" Q6NT89 1 26993692-27000886 "Predicted intracellular proteins" "Cell cycle, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 82.9;retina: 81.7;stomach 1: 121.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.6;Bipolar cells: 383.2;Gastric mucus-secreting cells: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Smooth muscle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 25: Bipolar cells - Visual perception" "unprognostic (1.41e-1)" "unprognostic (7.15e-2)" "unprognostic (7.70e-2)" "unprognostic (1.15e-1)" "unprognostic (2.88e-3)" "unprognostic (6.23e-2)" "prognostic unfavorable (1.90e-6)" "unprognostic (3.53e-1)" "unprognostic (8.39e-3)" "unprognostic (1.64e-1)" "unprognostic (1.90e-1)" "unprognostic (9.71e-3)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.55e-1)" "unprognostic (5.56e-2)" "unprognostic (1.88e-1)" "unprognostic (2.55e-2)" TSPAN1 "NET-1, TSPAN-1" ENSG00000117472 "Tetraspanin 1" O60635 1 46175073-46185962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 573.8;kidney: 237.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 992.2;Club cells: 705.5;Distal enterocytes: 2274.7;Intestinal goblet cells: 730.3;Ionocytes: 1033.4;Late spermatids: 805.6;Paneth cells: 807.5" "Cancer enhanced" "Detected in all" "prostate cancer: 455.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 57 "plasmacytoid DC: 5.6" "Lineage enriched" "Detected in single" 57 "dendritic cells: 5.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 217.9" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA011909 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 45: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" 3 "Nucleoplasm, Vesicles" "HPA011909: AB_2668565" "unprognostic (1.21e-1)" "unprognostic (3.11e-1)" "unprognostic (3.67e-2)" "unprognostic (4.12e-1)" "unprognostic (2.69e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-2)" "unprognostic (1.44e-1)" "unprognostic (1.88e-3)" "unprognostic (8.73e-2)" "prognostic favorable (9.28e-6)" "unprognostic (5.90e-2)" "unprognostic (2.61e-1)" "unprognostic (4.90e-2)" "unprognostic (4.30e-2)" TSPAN8 "CO-029, TM4SF3" ENSG00000127324 "Tetraspanin 8" P19075 12 71125085-71441898 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 919.6;stomach 1: 614.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3097.9;Ductal cells: 947.7;Enteroendocrine cells: 836.8;Intestinal goblet cells: 813.6;Paneth cells: 1988.4;Proximal enterocytes: 3369.5;Undifferentiated cells: 1654.2" "Group enriched" "Detected in many" 4 "colorectal cancer: 283.9;pancreatic cancer: 156.9;stomach cancer: 194.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 618.1;Gastric cancer: 461.0" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA022273, CAB026009, HPA044337" Enhanced Approved Vesicles NA NA "Cluster 45: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 4 Vesicles "CAB026009: , HPA022273: , HPA044337: AB_2678899" "unprognostic (1.64e-1)" "unprognostic (2.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.40e-2)" "unprognostic (6.81e-2)" "unprognostic (7.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.01e-3)" "unprognostic (2.93e-1)" "prognostic unfavorable (9.66e-5)" "unprognostic (1.88e-2)" "unprognostic (1.00e-1)" "unprognostic (2.97e-2)" "prognostic favorable (7.36e-5)" TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 547.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 654.9;Hepatocytes: 425.1;Paneth cells: 290.1;Proximal enterocytes: 290.1" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.9;monocytes: 17.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" TTC22 FLJ20619 ENSG00000006555 "Tetratricopeptide repeat domain 22" Q5TAA0 1 54779712-54801323 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 106.5;vagina: 46.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 44.9;Intestinal goblet cells: 31.0;Paneth cells: 32.4;Proximal enterocytes: 51.0;Squamous epithelial cells: 22.7;Suprabasal keratinocytes: 37.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" HPA035072 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA035072: AB_10602252" "prognostic favorable (2.06e-4)" "unprognostic (8.52e-2)" "unprognostic (4.84e-2)" "unprognostic (4.98e-2)" "unprognostic (1.01e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.02e-1)" "unprognostic (2.60e-1)" "unprognostic (3.07e-2)" "unprognostic (4.57e-2)" "unprognostic (7.27e-2)" "unprognostic (1.51e-3)" "unprognostic (5.08e-3)" "unprognostic (1.00e-1)" "unprognostic (3.16e-2)" "unprognostic (2.21e-1)" TTC39A "C1orf34, DEME-6, KIAA0452" ENSG00000085831 "Tetratricopeptide repeat domain 39A" Q5SRH9 1 51287258-51345116 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 57.8" "Group enriched" "Detected in many" 8 "Early spermatids: 395.7;Late spermatids: 628.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 47 "plasmacytoid DC: 31.8" "Lineage enriched" "Detected in single" 47 "dendritic cells: 31.8" "Cancer enhanced" "Detected in many" "breast cancer: 65.1" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028098, HPA043440" Uncertain Enhanced Centrosome NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 46: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Late spermatids - Unknown function" Centrosome "HPA028098: AB_10601705, HPA043440: AB_2678483" "unprognostic (5.05e-2)" "unprognostic (1.95e-1)" "unprognostic (3.35e-2)" "unprognostic (7.60e-2)" "unprognostic (8.53e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (5.05e-5)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (8.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.89e-2)" "unprognostic (1.73e-3)" "unprognostic (5.40e-2)" "unprognostic (5.96e-2)" "unprognostic (1.06e-1)" UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760270-233773300 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "intestine: 195.3;liver: 314.0" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 93.5" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.4" "Cancer enhanced" "Detected in many" "liver cancer: 47.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636448-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 21.2;intestine: 76.9;stomach 1: 31.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.8;Distal enterocytes: 1.9;Gastric mucus-secreting cells: 4.7;Intestinal goblet cells: 1.2;Paneth cells: 1.4;Proximal enterocytes: 3.3;Squamous epithelial cells: 4.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 81.8;Gallbladder cancer: 131.7;pancreatic cancer: 71.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681901-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "esophagus: 81.4" "Group enriched" "Detected in some" 7 "Basal squamous epithelial cells: 11.1;Squamous epithelial cells: 44.3" "Group enriched" "Detected in some" 10 "cervical cancer: 1.2;head and neck cancer: 2.3;lung cancer: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 10.5;Esophageal cancer: 6.6;Kidney cancer: 6.8" "Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (1.03e-2)" "unprognostic (1.09e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-7)" "unprognostic (2.14e-1)" "unprognostic (4.57e-2)" UPK1B "TSPAN20, UPK1" ENSG00000114638 "Uroplakin 1B" O75841 3 119173517-119205143 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 32.9;urinary bladder: 85.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 32.4;Club cells: 157.8;Glandular and luminal cells: 82.2;Ionocytes: 34.6;Mesothelial cells: 123.1" "Cancer enriched" "Detected in many" 4 "urothelial cancer: 147.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 251.9" "Adipose visceral - Mesothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA031799, HPA031800" Enhanced NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 41 "HPA031799: AB_10671579, HPA031800: AB_10671580" "unprognostic (1.20e-2)" "unprognostic (7.18e-2)" "prognostic favorable (3.87e-5)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (8.77e-3)" "unprognostic (3.67e-1)" "unprognostic (2.71e-1)" "unprognostic (3.26e-2)" "unprognostic (2.03e-1)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.76e-4)" "unprognostic (1.68e-1)" "unprognostic (6.76e-2)" "unprognostic (2.95e-2)" USH1C "AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C" ENSG00000006611 "USH1 protein network component harmonin" Q9Y6N9 11 17493895-17544416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Hearing" "Cancer-related genes, Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 95.1;kidney: 52.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 203.0;Enteroendocrine cells: 95.9;Intestinal goblet cells: 93.0;Muller glia cells: 154.1;Paneth cells: 173.3;Proximal enterocytes: 432.4;Proximal tubular cells: 179.4;Undifferentiated cells: 94.6" "Group enriched" "Detected in many" 7 "colorectal cancer: 34.5;pancreatic cancer: 18.8;renal cancer: 29.4;stomach cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 76.6;Gastric cancer: 40.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Cholangiocyte, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB013690, HPA027398, HPA027492, HPA028033" Enhanced Enhanced Cytosol No NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 4 Cytosol "CAB013690: , HPA027398: AB_10601775, HPA027492: AB_10601898, HPA028033: AB_10601782" "unprognostic (3.60e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-1)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.51e-2)" "unprognostic (9.65e-2)" "prognostic favorable (9.41e-4)" "unprognostic (1.29e-2)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (2.61e-1)" VAMP8 "EDB, VAMP-8" ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1201.5;Proximal enterocytes: 1181.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Heart muscle - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Non-specific - Mixed function" 3 "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" VPS37B FLJ12750 ENSG00000139722 "VPS37B subunit of ESCRT-I" Q9H9H4 12 122865330-122896127 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 156.0;NK-cells: 189.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038217, HPA038218" Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 22 "HPA038217: AB_10672740, HPA038218: AB_2675898" "unprognostic (1.63e-2)" "unprognostic (1.53e-1)" "unprognostic (1.84e-1)" "unprognostic (1.38e-1)" "unprognostic (8.33e-2)" "unprognostic (2.58e-1)" "unprognostic (4.30e-2)" "unprognostic (3.25e-2)" "unprognostic (8.26e-3)" "unprognostic (2.51e-1)" "unprognostic (5.57e-2)" "unprognostic (3.01e-1)" "prognostic favorable (1.35e-6)" "unprognostic (2.58e-3)" "unprognostic (6.38e-2)" "unprognostic (4.02e-2)" "unprognostic (2.44e-2)" VSIG1 "GPA34, MGC44287" ENSG00000101842 "V-set and immunoglobulin domain containing 1" Q86XK7 X 108044970-108079184 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "stomach 1: 188.6" "Cell type enriched" "Detected in some" 28 "Gastric mucus-secreting cells: 311.9" "Group enriched" "Detected in many" 17 "lung cancer: 8.7;pancreatic cancer: 17.7;stomach cancer: 31.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 12.0;T-reg: 13.0" "Lineage enriched" "Detected in many" 5 "T-cells: 13.0" "Cancer enhanced" "Detected in some" "Gastric cancer: 9.2;liver cancer: 16.3;pancreatic cancer: 8.0" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "medulla oblongata: 11.5;spinal cord: 27.4" "HPA001445, HPA036310, HPA036311" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" 4 "Vesicles, Cytosol" "HPA001445: AB_10669749, HPA036310: AB_10670795, HPA036311: AB_10673350" "unprognostic (4.33e-3)" "unprognostic (4.60e-2)" "unprognostic (3.22e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-1)" "unprognostic (4.80e-2)" "unprognostic (3.25e-2)" "unprognostic (9.79e-2)" "unprognostic (4.58e-1)" "unprognostic (2.35e-2)" "unprognostic (2.11e-2)" "unprognostic (1.25e-1)" "unprognostic (6.31e-7)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (2.19e-2)" "unprognostic (2.23e-3)" VWA3B "DKFZp686F2227, MGC26733" ENSG00000168658 "Von Willebrand factor A domain containing 3B" Q502W6 2 98087116-98313299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 9.1;fallopian tube: 21.5;testis: 29.2" "Group enriched" "Detected in some" 8 "Early spermatids: 381.2;Late spermatids: 1004.2" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 4 "hippocampal formation: 7.1" "Low region specificity" "Detected in many" "HPA036700, HPA036701" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA036700: AB_2675261, HPA036701: AB_10673505" "unprognostic (2.36e-2)" "unprognostic (4.27e-2)" "unprognostic (1.23e-1)" "unprognostic (1.01e-3)" "unprognostic (5.16e-2)" "unprognostic (3.27e-1)" "unprognostic (1.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (1.44e-2)" "unprognostic (4.53e-2)" "unprognostic (6.41e-2)" "unprognostic (2.63e-7)" "unprognostic (2.57e-1)" "unprognostic (5.04e-2)" "unprognostic (2.27e-1)" "unprognostic (4.96e-2)" VWA7 "C6orf27, G7c, NG37" ENSG00000204396 "Von Willebrand factor A domain containing 7" Q9Y334 6 31765590-31777328 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 20.7" "Cell type enhanced" "Detected in some" "Ciliated cells: 3.9;Distal enterocytes: 2.2;Gastric mucus-secreting cells: 7.7;Proximal enterocytes: 4.8;Proximal tubular cells: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Group enriched" "Detected in some" 5 "cerebellum: 7.0;pons and medulla: 3.9" "Low region specificity" "Detected in many" "HPA046954, HPA054262" Approved Approved "Plasma membrane,Cytosol" "Secreted - unknown location" "No annotated function" NA NA 9200 "Cluster 66: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA046954: AB_2679875, HPA054262: AB_2682430" "unprognostic (9.13e-2)" "unprognostic (8.60e-4)" "unprognostic (9.99e-2)" "unprognostic (2.43e-1)" "unprognostic (2.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.38e-2)" "unprognostic (4.40e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-2)" "unprognostic (1.65e-2)" "unprognostic (9.25e-2)" "prognostic favorable (4.35e-8)" "unprognostic (3.75e-2)" "unprognostic (2.37e-1)" "unprognostic (9.48e-2)" "unprognostic (7.66e-2)" ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 136.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "Golgi apparatus" "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" ZNF165 "CT53, ZSCAN7" ENSG00000197279 "Zinc finger protein 165" P49910 6 28080568-28089563 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 19.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 86.5;Early spermatids: 209.9;Glandular and luminal cells: 71.2;Mucus glandular cells: 66.0;Syncytiotrophoblasts: 89.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in many" HPA007247 Approved "Nuclear speckles,Microtubules" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 31 "Nuclear speckles, Microtubules" "HPA007247: AB_2797217" "unprognostic (1.85e-1)" "unprognostic (2.01e-3)" "unprognostic (1.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.45e-1)" "unprognostic (4.32e-3)" "unprognostic (3.42e-1)" "unprognostic (2.09e-1)" "unprognostic (1.93e-2)" "prognostic favorable (2.10e-4)" "unprognostic (1.18e-3)" "unprognostic (1.29e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.10e-1)" "unprognostic (2.40e-1)" "unprognostic (2.18e-1)" "prognostic favorable (9.82e-5)"