Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "intestine: 44.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 144.4;Enteroendocrine cells: 35.4;Intestinal goblet cells: 62.6;Paneth cells: 62.1;Proximal enterocytes: 82.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 11.1;pancreatic cancer: 14.9" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 11.4" "HPA054092, HPA054684" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "HPA054092: AB_2682375, HPA054684: AB_2682573" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "prognostic favorable (6.36e-4)" "unprognostic (9.23e-2)" "unprognostic (4.62e-2)" "unprognostic (4.06e-2)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.86e-3)" "unprognostic (1.67e-1)" "unprognostic (6.09e-4)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" B4GALNT2 "Cad, GALGT2, Sda" ENSG00000167080 "Beta-1,4-N-acetyl-galactosaminyltransferase 2" Q8NHY0 17 49132460-49176840 "Disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.8;Distal enterocytes: 29.9;Enteroendocrine cells: 6.6;Glandular and luminal cells: 6.2;Intestinal goblet cells: 25.3;Proximal enterocytes: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Skin - Outer root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015721 Approved NA NA "Cluster 45: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" 2 "HPA015721: AB_1845245" "unprognostic (4.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.26e-3)" "unprognostic (2.03e-4)" "unprognostic (1.72e-2)" "unprognostic (2.62e-2)" "unprognostic (3.67e-2)" "unprognostic (7.67e-2)" "unprognostic (4.06e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.29e-5)" "unprognostic (3.53e-1)" "unprognostic (1.31e-1)" "unprognostic (7.81e-3)" "unprognostic (2.15e-1)" CA6 ENSG00000131686 "Carbonic anhydrase 6" P23280 1 8945867-8975092 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted secreted proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 296 "salivary gland: 9125.4" "Cell type enriched" "Detected in some" 51 "Serous glandular cells: 8255.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "naive CD4 T-cell: 5.7;naive CD8 T-cell: 16.6" "Lineage enriched" "Detected in many" 12 "T-cells: 16.6" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.3" "Breast - Breast glandular cells (progenitors)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028550, HPA028692" Enhanced "Secreted to digestive system" Enzyme NA NA 24000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 6: Non-specific - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" "HPA028550: AB_10600105, HPA028692: AB_10601883" "unprognostic (2.54e-5)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "unprognostic (2.90e-1)" "unprognostic (9.28e-2)" "unprognostic (2.70e-3)" "unprognostic (1.24e-1)" "unprognostic (1.73e-1)" "unprognostic (5.93e-2)" "unprognostic (4.41e-2)" "unprognostic (4.29e-5)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-1)" CCDC201 ENSG00000283247 "Coiled-coil domain containing 201" A0A1B0GTI1 7 45859994-45873082 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "Oocytes: 30.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells (progenitors)" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Rhabdoid - Membrane components" "Cluster 44: Oocytes - Unknown function" CES3 "ES31, FLJ21736" ENSG00000172828 "Carboxylesterase 3" Q6UWW8 16 66961245-66975149 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.1;liver: 51.2;skeletal muscle: 23.9" "Group enriched" "Detected in many" 5 "Distal enterocytes: 106.8;Enteroendocrine cells: 31.6;Hepatocytes: 43.0;Intestinal goblet cells: 27.9;Paneth cells: 74.2;Proximal enterocytes: 63.1;Undifferentiated cells: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA041008, HPA041307" Approved Approved "Nuclear membrane,Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA 1200000 "Cluster 19: Eosinophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Enterocytes - Absorption" "Nuclear membrane, Endoplasmic reticulum" "HPA041008: AB_2677247, HPA041307: AB_2677400" "unprognostic (3.91e-3)" "unprognostic (1.22e-1)" "unprognostic (1.94e-2)" "unprognostic (8.99e-3)" "unprognostic (9.32e-2)" "unprognostic (7.84e-4)" "prognostic favorable (7.26e-5)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (6.43e-2)" "unprognostic (1.84e-2)" "unprognostic (1.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.75e-1)" "unprognostic (3.31e-2)" "unprognostic (7.41e-2)" CFAP73 "CCDC42B, MIA2" ENSG00000186710 "Cilia and flagella associated protein 73" A6NFT4 12 113149724-113159276 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 30.5;fallopian tube: 41.0" "Cell type enriched" "Detected in some" 9 "Ciliated cells: 148.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.1" "Breast - Breast glandular cells (progenitors), Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA048539 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 6: Leukemia - Signal transduction" "Cluster 42: Ciliated cells - Cilium assembly" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA048539: AB_2680434" "unprognostic (2.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.90e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.18e-3)" "unprognostic (6.49e-2)" "unprognostic (2.94e-1)" "unprognostic (1.33e-1)" "unprognostic (3.14e-1)" "unprognostic (5.68e-2)" "unprognostic (3.43e-2)" "unprognostic (1.62e-4)" "unprognostic (2.03e-4)" "unprognostic (1.60e-1)" "unprognostic (4.03e-2)" "unprognostic (1.55e-2)" CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 44.0;prostate: 28.7;salivary gland: 28.0" "Cell type enriched" "Detected in some" 5 "Prostatic glandular cells: 48.9" "Cancer enriched" "Detected in some" 16 "prostate cancer: 27.9" "Group enriched" "Detected in many" 5 "amygdala: 42.4;basal ganglia: 59.5;cerebral cortex: 69.7;hippocampal formation: 63.2;white matter: 36.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 3.4;Neuroblastoma: 8.7;prostate cancer: 2.5" "Breast - Breast glandular cells (progenitors), Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA014101 Enhanced Supported NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 40: Prostatic glandular cells - Transcription" "HPA014101: AB_1854210" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-1)" "unprognostic (8.57e-4)" "unprognostic (4.88e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 138.6;pancreas: 206.1;salivary gland: 116.0;stomach 1: 111.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 311.2;Exocrine glandular cells: 293.7;Proximal enterocytes: 846.1;Serous glandular cells: 260.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Region enriched" "Detected in single" 9 "choroid plexus: 2.3" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cancer enhanced" "Detected in many" "breast cancer: 12.3;colorectal cancer: 8.6;lung cancer: 7.7" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells (progenitors), Liver - Cholangiocyte, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" Cytokine NA NA 2080000 250000 "Cluster 48: Stomach - Proteolysis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 3 Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" FEZF2 "FEZL, FKSG36, FLJ10142, TOF, Zfp312, ZNF312" ENSG00000153266 "FEZ family zinc finger 2" Q8TBJ5 3 62369681-62374324 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 27.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 39.7;Oocytes: 60.3" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 6 "cerebral cortex: 329.8;hippocampal formation: 114.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells (progenitors)" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "amygdala: 21.4;cerebral cortex: 21.8;hippocampal formation: 38.3" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "unprognostic (2.37e-1)" "unprognostic (1.74e-2)" "unprognostic (1.70e-1)" HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;skin 1: 4.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.1;Langerhans cells: 1.4;Proximal enterocytes: 3.4;Spermatocytes: 3.4;Suprabasal keratinocytes: 2.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 15.8;breast cancer: 14.9" "Breast - Breast glandular cells (progenitors), Testis - Spermatocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "spinal cord: 1.4" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Skin - Cornification" "Cluster 65: Non-specific - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 4 Nucleoplasm Cytosol "HPA038291: AB_10674552" "unprognostic (1.50e-3)" "unprognostic (1.93e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (6.90e-3)" "unprognostic (1.32e-2)" "unprognostic (7.41e-3)" "unprognostic (4.46e-3)" "unprognostic (2.25e-1)" "unprognostic (3.26e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" HOXC13 "HOX3, HOX3G" ENSG00000123364 "Homeobox C13" P31276 12 53938831-53946544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "skin 1: 9.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.2;Breast myoepithelial cells: 4.2;Melanocytes: 1.7;Oocytes: 1.5;Spermatogonia: 1.6;Suprabasal keratinocytes: 2.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA051634 Enhanced NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "HPA051634: AB_2616459" "unprognostic (5.16e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.27e-3)" "unprognostic (2.78e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (4.04e-2)" "unprognostic (1.53e-1)" "unprognostic (9.77e-2)" "unprognostic (9.74e-9)" "unprognostic (2.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.68e-1)" IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1163.6" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 900.0" "Cancer enriched" "Detected in many" 29 "liver cancer: 385.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 38.2;liver cancer: 75.4;ovarian cancer: 50.4" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" Other NA NA 28100000 25000000 "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 43: Hepatocytes - Metabolism" 3 "Golgi apparatus" "CAB004445: AB_627782, HPA046972: AB_2679884, HPA050640: AB_2681197" "unprognostic (8.66e-3)" "unprognostic (1.45e-1)" "unprognostic (9.41e-2)" "unprognostic (7.80e-2)" "unprognostic (7.04e-2)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.89e-2)" "unprognostic (2.09e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.90e-11)" "prognostic unfavorable (6.64e-4)" "unprognostic (7.20e-2)" "unprognostic (7.98e-2)" "unprognostic (3.43e-1)" KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911934-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 29 "brain: 46.8;choroid plexus: 24.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.0;Extravillous trophoblasts: 17.6;Inhibitory neurons: 8.4;Oligodendrocyte precursor cells: 17.0;Syncytiotrophoblasts: 7.5" "Cancer enriched" "Detected in many" 7 "glioma: 27.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 11.5;lung cancer: 9.0" "Breast - Breast glandular cells (progenitors), Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014738, HPA062278" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" 9 "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA014738: AB_1852114, HPA062278: AB_2732679" "unprognostic (2.54e-1)" "unprognostic (6.06e-3)" "unprognostic (1.37e-1)" "unprognostic (3.07e-2)" "unprognostic (4.39e-2)" "unprognostic (7.41e-4)" "unprognostic (1.54e-3)" "unprognostic (4.83e-5)" "unprognostic (1.57e-1)" "unprognostic (6.95e-2)" "unprognostic (1.60e-2)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (3.10e-4)" "unprognostic (2.37e-1)" "unprognostic (4.28e-2)" "unprognostic (4.08e-2)" KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43780976 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 122.7" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 223.3;Syncytiotrophoblasts: 783.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 7 "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "placenta: 131.0" "Cell type enriched" "Detected in some" 92 "Extravillous trophoblasts: 1216.7" "Cancer enhanced" "Detected in many" "stomach cancer: 48.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 49.8" "Breast - Breast glandular cells (progenitors), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" Enzyme NA NA 1900000 "Cluster 58: Placenta - Pregnancy" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "Endoplasmic reticulum" "HPA022851: " "unprognostic (1.49e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-2)" "unprognostic (4.80e-3)" "unprognostic (1.97e-1)" "unprognostic (9.02e-3)" "unprognostic (3.01e-2)" "unprognostic (1.01e-2)" "unprognostic (6.49e-2)" "unprognostic (8.72e-2)" "unprognostic (1.40e-1)" "unprognostic (2.01e-2)" "unprognostic (4.48e-6)" "unprognostic (1.76e-1)" "unprognostic (9.88e-2)" "unprognostic (1.22e-3)" "unprognostic (1.00e-1)" OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985713-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.9;Rhabdoid: 5.3" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" PHLDA1 "DT1P1B11, PHRIP, TDAG51" ENSG00000139289 "Pleckstrin homology like domain family A member 1" Q8WV24 12 76025447-76031776 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 154.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 336.6;Lymphatic endothelial cells: 270.4;Melanocytes: 276.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 6 "monocytes: 1.1;T-cells: 1.6" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells (progenitors)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016160, HPA019000, HPA063520" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 48: Smooth muscle cells - Signal transduction" 4 "Nucleoli, Nucleoli rim" Nucleoplasm "CAB016160: AB_628117, HPA019000: AB_1855309, HPA063520: AB_2685028" "unprognostic (9.09e-2)" "unprognostic (2.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.51e-3)" "unprognostic (2.33e-1)" "unprognostic (2.60e-3)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (2.21e-1)" "unprognostic (1.16e-1)" "unprognostic (5.21e-3)" "unprognostic (5.03e-2)" "unprognostic (1.21e-1)" "unprognostic (3.34e-2)" "unprognostic (2.32e-1)" "unprognostic (1.29e-1)" "unprognostic (4.55e-3)" PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248085-25298012 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 156.4;Salivary duct cells: 136.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells (progenitors), Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031067 Approved Approved Cytosol NA NA 14000000 "Cluster 33: Non-specific - ATP binding" "Cluster 80: Non-specific - Endocytosis" "Cluster 45: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 4 Cytosol "HPA031067: AB_2673722" "unprognostic (6.13e-2)" "unprognostic (5.98e-2)" "unprognostic (1.21e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.37e-4)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.23e-3)" "unprognostic (8.39e-3)" "unprognostic (1.58e-3)" "unprognostic (1.98e-1)" "unprognostic (1.22e-2)" "unprognostic (3.41e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.43e-4)" SCGB3A1 "HIN-1, HIN1, LU105, PnSP-2, UGRP2" ENSG00000161055 "Secretoglobin family 3A member 1" Q96QR1 5 180590105-180591499 "Plasma proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 259.9;lung: 492.9;salivary gland: 724.7" "Group enriched" "Detected in many" 4 "Club cells: 32504.6;Ionocytes: 15631.2" "Group enriched" "Detected in many" 7 "endometrial cancer: 114.2;lung cancer: 288.1" "Group enriched" "Detected in many" 7 "choroid plexus: 24.2;hypothalamus: 11.7" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 52.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.0" "Breast - Breast glandular cells (progenitors), Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" Cytokine NA NA 10000000 "Cluster 25: Non-specific - Unknown function" "Cluster 38: Salivary gland - Salivary secretion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" "unprognostic (7.70e-3)" "unprognostic (4.90e-1)" "unprognostic (1.53e-2)" "unprognostic (1.08e-2)" "unprognostic (3.03e-1)" "unprognostic (1.36e-2)" "unprognostic (7.87e-3)" "unprognostic (2.00e-2)" "unprognostic (3.20e-1)" "unprognostic (4.88e-2)" "unprognostic (3.55e-2)" "unprognostic (7.19e-2)" "unprognostic (8.74e-3)" "unprognostic (5.43e-2)" "unprognostic (4.62e-1)" "unprognostic (4.50e-1)" "unprognostic (1.50e-2)" SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 84.5;skin 1: 31.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 393.3;Breast myoepithelial cells: 338.2;Distal enterocytes: 121.1;Hepatocytes: 113.3;Intestinal goblet cells: 129.9;Melanocytes: 211.3;Muller glia cells: 101.1;Undifferentiated cells: 107.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 2.5" "Lineage enriched" "Detected in single" 19 "granulocytes: 2.5" "Cancer enhanced" "Detected in many" "breast cancer: 7.9" "Breast - Breast glandular cells (progenitors), Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" "No annotated function" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 22: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 17: Breast glandular cells - Lactation" 20 "Nucleoplasm, Nucleoli" "HPA052824: AB_2681964" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-1)" "unprognostic (4.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (4.30e-7)" "unprognostic (1.83e-3)" "unprognostic (8.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.33e-2)"