Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" DACT3 "DAPPER3, MGC15476, RRR1" ENSG00000197380 "Dishevelled binding antagonist of beta catenin 3" Q96B18 19 46647551-46661182 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.0" "Cell type enhanced" "Detected in many" "Early spermatids: 23.8;Horizontal cells: 22.7;Oligodendrocytes: 25.3;Smooth muscle cells: 34.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.1" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043053 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 64: Neuronal - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Smooth muscle cells - Muscle contraction" Vesicles Nucleoplasm "HPA043053: AB_10794769" "unprognostic (2.35e-1)" "unprognostic (3.08e-1)" "unprognostic (5.30e-3)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-2)" "unprognostic (3.27e-2)" "unprognostic (2.03e-4)" "unprognostic (1.70e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.59e-2)" "unprognostic (4.03e-2)" "unprognostic (3.54e-3)" "prognostic unfavorable (6.66e-4)" FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1162.8;intestine: 1412.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 636.6;monocytes: 495.4;Peritubular cells: 475.9;Smooth muscle cells: 758.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 33: Non-specific - ATP binding" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 32: Smooth muscle cells - Muscle contraction" 18 "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" IRAG1 "IRAG, JAW1L, MRVI1" ENSG00000072952 "Inositol 1,4,5-triphosphate receptor associated 1" Q9Y6F6 11 10573091-10693988 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 165.7;Early spermatids: 46.9;Peritubular cells: 85.2;Sertoli cells: 35.4;Smooth muscle cells: 105.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 24.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 24.0" "Cancer enhanced" "Detected in some" "testis cancer: 4.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in many" 5 "thalamus: 7.6" "Low region specificity" "Detected in all" HPA008704 Uncertain Approved "Nuclear bodies,Cytosol" NA NA 220000 "Cluster 28: Neutrophils - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" Cytosol "Nuclear bodies" "HPA008704: AB_1079413" "unprognostic (2.18e-1)" "unprognostic (3.40e-2)" "unprognostic (2.86e-3)" "prognostic favorable (5.78e-4)" "unprognostic (5.30e-1)" "unprognostic (3.37e-3)" "unprognostic (1.04e-2)" "unprognostic (1.87e-1)" "unprognostic (5.63e-3)" "unprognostic (1.04e-2)" "unprognostic (1.48e-1)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (3.72e-2)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-3)" SMTN ENSG00000183963 Smoothelin P53814 22 31064105-31104757 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 833.4;urinary bladder: 434.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 249.8;Lymphatic endothelial cells: 104.4;Smooth muscle cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001721, HPA051778, HPA058590" Enhanced Supported "Nucleoplasm,Actin filaments" No Yes 140000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Smooth muscle cells - Muscle contraction" Nucleoplasm "Actin filaments" "CAB001721: , HPA051778: AB_2681607, HPA058590: AB_2683765" "unprognostic (1.36e-2)" "unprognostic (4.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (1.08e-3)" "unprognostic (2.05e-2)" "unprognostic (4.56e-1)" "unprognostic (2.15e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (2.75e-2)" "unprognostic (1.84e-1)" "unprognostic (8.41e-3)" "unprognostic (6.34e-2)"