Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22635077-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 621.7;lymphoid tissue: 1066.3" "Group enriched" "Detected in many" 5 "Hofbauer cells: 1545.9;Kupffer cells: 3931.0;Macrophages: 1776.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 38 "intermediate monocyte: 227.9;non-classical monocyte: 184.6" "Lineage enriched" "Detected in many" 59 "monocytes: 227.9" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" "Complement pathway" NA NA 2700000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 58: Macrophages - Innate immune response" 3 "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 973.1" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1340.6;Kupffer cells: 3907.0;Macrophages: 1814.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 142.5;non-classical monocyte: 103.0" "Lineage enriched" "Detected in many" 83 "monocytes: 142.5" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" "Complement pathway" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643014-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 923.4" "Group enriched" "Detected in many" 5 "Hofbauer cells: 1156.0;Kupffer cells: 1255.6;Macrophages: 969.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "intermediate monocyte: 56.5" "Lineage enriched" "Detected in single" 559 "monocytes: 56.5" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" "Complement pathway" NA NA 513000000 2100000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 3 "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.0" "Group enriched" "Detected in many" 5 "granulocytes: 59.3;Hofbauer cells: 171.3;Kupffer cells: 155.4;Macrophages: 151.8;monocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 902.8;eosinophil: 452.5;intermediate monocyte: 274.2;non-classical monocyte: 373.1" "Group enriched" "Detected in many" 20 "granulocytes: 902.8;monocytes: 373.1" "Cancer enhanced" "Detected in some" "Leukemia: 5.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633700 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 347.3" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2936.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3500.8" "Group enriched" "Detected in all" 6 "granulocytes: 935.1;monocytes: 3500.8" "Cancer enhanced" "Detected in many" "breast cancer: 11.9;head and neck cancer: 9.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Hepatocytes, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" Immunity NA NA 2750000000 10000000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Liver - Plasma proteins" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" CD68 "DKFZp686M18236, GP110, LAMP4, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 346.5;lymphoid tissue: 360.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 223.6;Kupffer cells: 258.2;Langerhans cells: 80.9;Macrophages: 190.0;Proximal enterocytes: 193.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3264.9;intermediate monocyte: 3664.2;non-classical monocyte: 3764.8" "Group enriched" "Detected in all" 11 "dendritic cells: 1382.0;monocytes: 3764.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 7 "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.5" "Cell type enhanced" "Detected in some" "Hofbauer cells: 151.9;Kupffer cells: 91.5;Langerhans cells: 191.7;Macrophages: 142.5;Microglial cells: 75.1;monocytes: 464.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 80.1;intermediate monocyte: 79.2;memory B-cell: 41.1;myeloid DC: 79.0;naive B-cell: 28.7;non-classical monocyte: 85.6" "Group enriched" "Detected in many" 18 "B-cells: 41.1;dendritic cells: 79.0;monocytes: 85.6" "Cancer enriched" "Detected in some" 6 "lymphoma: 54.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 14: Langerhans cells - Innate immune response" 1 "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780018-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 157.3;lymphoid tissue: 145.7" "Cell type enhanced" "Detected in many" "dendritic cells: 329.2;Hofbauer cells: 223.4;Kupffer cells: 356.9;Macrophages: 445.8;monocytes: 644.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 318.5" "Group enriched" "Detected in many" 5 "dendritic cells: 80.2;granulocytes: 106.4;monocytes: 318.5" "Group enriched" "Detected in some" 4 "Leukemia: 15.8;lymphoma: 29.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 142.7" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 585.8;Syncytiotrophoblasts: 295.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.9;memory B-cell: 18.7;naive B-cell: 14.8;non-classical monocyte: 6.4" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.4" "Cancer enriched" "Detected in many" 4 "lymphoma: 69.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046635 Enhanced "Secreted to blood" Cytokine NA NA 203000 1400000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 224.8;placenta: 473.0" "Group enriched" "Detected in many" 4 "Hofbauer cells: 791.5;Langerhans cells: 206.4;Macrophages: 321.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.3;myeloid DC: 179.8" "Group enriched" "Detected in many" 184 "dendritic cells: 179.8;granulocytes: 50.0;monocytes: 141.3" "Cancer enhanced" "Detected in some" "cervical cancer: 13.1;Leukemia: 20.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" "Blood coagulation" NA NA 1400000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Placenta - Pregnancy" "Cluster 8: Immune cells - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 12 "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" FOLR2 FRbeta ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 162.7" "Cell type enriched" "Detected in many" 5 "Hofbauer cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.4;intermediate monocyte: 50.8" "Group enriched" "Detected in many" 4 "dendritic cells: 18.8;monocytes: 64.4" "Group enriched" "Detected in some" 18 "Leukemia: 1.8;lymphoma: 4.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Receptor NA NA 15000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 58: Placenta - Pregnancy" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 359.1;lymphoid tissue: 167.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 750.2;Kupffer cells: 648.1;Langerhans cells: 317.3;Macrophages: 491.9;monocytes: 638.7;NK-cells: 687.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Bone cancer: 64.2;Leukemia: 194.5;lymphoma: 74.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 21 "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.5;lymphoid tissue: 59.7" "Group enriched" "Detected in some" 7 "Hofbauer cells: 68.1;Kupffer cells: 100.6;Macrophages: 81.5;monocytes: 208.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.9;eosinophil: 357.0;intermediate monocyte: 512.1;myeloid DC: 229.7;neutrophil: 574.9;non-classical monocyte: 710.4" "Group enriched" "Detected in all" 60 "dendritic cells: 229.7;granulocytes: 574.9;monocytes: 710.4" "Cancer enhanced" "Detected in some" "Leukemia: 2.3;lymphoma: 2.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Monocytes - Innate immune response" 30 "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 264.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 399.9;Kupffer cells: 528.6;Macrophages: 538.4;monocytes: 1168.6;Squamous epithelial cells: 370.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.9" "Lineage enriched" "Detected in many" 15 "monocytes: 121.9" "Cancer enhanced" "Detected in many" "Bone cancer: 29.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Fibroblasts, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 40: Monocytes - Innate immune response" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 58: Macrophages - Innate immune response" 5 Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 118.5" "Group enriched" "Detected in many" 4 "Breast glandular cells: 124.7;Hofbauer cells: 157.9;Kupffer cells: 348.2;Langerhans cells: 206.5;Lymphatic endothelial cells: 244.1;Macrophages: 414.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 20.4" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Cancer enriched" "Detected in some" 7 "Rhabdoid: 8.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 58: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 61.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 362.5;Kupffer cells: 426.5;Macrophages: 256.0;monocytes: 185.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 83.2;plasmacytoid DC: 27.8" "Group enriched" "Detected in many" 30 "dendritic cells: 27.8;monocytes: 83.2" "Cancer enhanced" "Detected in some" "Leukemia: 11.2;Myeloma: 11.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" HPA029323 Approved NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 57: Lung - Lung function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 58: Macrophages - Innate immune response" 12 "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" PLEK "P47, PLEK1" ENSG00000115956 Pleckstrin P08567 2 68365282-68397453 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 598.0" "Cell type enhanced" "Detected in many" "dendritic cells: 278.3;Hofbauer cells: 297.8;Langerhans cells: 549.0;Macrophages: 422.4;monocytes: 934.0;NK-cells: 260.6;Schwann cells: 228.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 43 "Leukemia: 118.8;lymphoma: 185.1;Myeloma: 58.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031838, HPA057341" Enhanced Approved Nucleoli NA NA 380000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" 2 Nucleoli "HPA031838: AB_10602146, HPA057341: AB_2732609" "unprognostic (2.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.52e-3)" "unprognostic (3.52e-1)" "unprognostic (3.08e-2)" "unprognostic (4.67e-2)" "unprognostic (3.40e-2)" "unprognostic (4.00e-2)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (3.57e-1)" "unprognostic (4.42e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.6;lymphoid tissue: 29.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 36.4;granulocytes: 74.7;Hofbauer cells: 76.0;Ionocytes: 32.0;Kupffer cells: 83.2;Langerhans cells: 86.2;Macrophages: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 256.9;eosinophil: 908.6;neutrophil: 749.9" "Group enriched" "Detected in many" 5 "granulocytes: 908.6;monocytes: 256.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 22.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027543 Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 2 "Nucleoplasm, Vesicles" "Plasma membrane" "HPA027543: AB_10610287" "unprognostic (2.22e-2)" "unprognostic (2.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.23e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.38e-2)" RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 8831.6" "Cell type enhanced" "Detected in many" "Adipocytes: 775.0;Alveolar cells type 1: 1360.4;Alveolar cells type 2: 1066.1;Gastric mucus-secreting cells: 767.6;Hofbauer cells: 1650.7;Macrophages: 1284.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 78.8;pancreatic cancer: 57.9;skin cancer: 60.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Pancreas - Exocrine glandular cells, Skeletal muscle - Macrophages, Testis - Sertoli cells, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" Enzyme NA NA 1100000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Macrophages - Innate immune response" 2 Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 107.8" "Group enriched" "Detected in many" 5 "B-cells: 132.1;dendritic cells: 422.0;Hofbauer cells: 260.5;Kupffer cells: 438.5;Langerhans cells: 223.1;Macrophages: 253.9;Schwann cells: 222.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1241.7" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 21.5;lymphoma: 7.2;Myeloma: 9.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" Enzyme NA NA 2600000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, RNA-binding" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 331.3;lung: 97.9;lymphoid tissue: 168.6" "Group enriched" "Detected in many" 4 "Hofbauer cells: 484.1;Kupffer cells: 311.1;Langerhans cells: 611.3;Macrophages: 436.9;monocytes: 544.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 180.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 180.0" "Group enriched" "Detected in some" 15 "Leukemia: 134.6;lymphoma: 69.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 3 Nucleoplasm "CAB004079: AB_10692379, HPA044653: AB_2679036" "unprognostic (4.45e-2)" "unprognostic (3.31e-3)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (5.97e-2)" "unprognostic (3.33e-2)" "unprognostic (5.28e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (2.79e-1)" "unprognostic (3.36e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (2.40e-1)" "unprognostic (4.92e-2)" TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 56.2" "Group enriched" "Detected in many" 5 "granulocytes: 69.0;Hofbauer cells: 108.6;Kupffer cells: 199.3;Macrophages: 132.4;Microglial cells: 182.5;monocytes: 175.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 291.7;classical monocyte: 291.1;eosinophil: 315.0;intermediate monocyte: 436.4;myeloid DC: 113.8;neutrophil: 258.5;non-classical monocyte: 404.5" "Group enriched" "Detected in all" 23 "dendritic cells: 113.8;granulocytes: 315.0;monocytes: 436.4" "Cancer enhanced" "Detected in many" "Kidney cancer: 14.7;Leukemia: 15.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" TLR8 "CD288, hTLR8" ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Disease related genes, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 10.3;lymphoid tissue: 16.3" "Group enriched" "Detected in some" 4 "Kupffer cells: 47.8;Macrophages: 21.5;monocytes: 51.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 73 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 77 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001608 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 73.5;Kupffer cells: 52.1;Langerhans cells: 15.2;Macrophages: 35.2;monocytes: 14.1;NK-cells: 24.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Leukemia: 29.2;lymphoma: 8.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062742 Approved Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 1 Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 589.1;lymphoid tissue: 413.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 5142.2;Kupffer cells: 3057.7;Langerhans cells: 2435.1;Macrophages: 2419.9;monocytes: 3438.0;NK-cells: 1312.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6461.2" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 26 "Leukemia: 111.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 5 "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 160.9" "Group enriched" "Detected in many" 4 "Hofbauer cells: 875.5;Kupffer cells: 649.1;Macrophages: 406.1" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 26 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 30 "dendritic cells: 17.8;monocytes: 18.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000, HPA072756" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 57: Lung - Lung function" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 3 "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776, HPA072756: " "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)"