Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6452.4;seminal vesicle: 5718.9;smooth muscle: 7795.8" "Group enriched" "Detected in many" 5 "Breast myoepithelial cells: 1306.5;Peritubular cells: 5208.0;Sertoli cells: 1990.8;Smooth muscle cells: 4036.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.8" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Bone cancer: 252.0;testis cancer: 273.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 121.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" CNN1 "Sm-Calp, SMCC" ENSG00000130176 "Calponin 1" P51911 19 11538767-11550323 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 1809.0;intestine: 2567.9;smooth muscle: 2123.7" "Group enriched" "Detected in many" 8 "Breast myoepithelial cells: 254.0;Early spermatids: 183.3;Late spermatids: 572.1;Peritubular cells: 218.2;Sertoli cells: 304.6;Smooth muscle cells: 420.7" "Cancer enhanced" "Detected in all" "prostate cancer: 142.1;stomach cancer: 103.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 58.4;testis cancer: 66.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000007, HPA014263" Enhanced Approved "Actin filaments" No No "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 3 "Actin filaments" "CAB000007: AB_2082148, HPA014263: AB_1847039" "unprognostic (4.98e-3)" "unprognostic (1.01e-1)" "unprognostic (3.04e-3)" "unprognostic (1.95e-1)" "unprognostic (2.47e-1)" "unprognostic (4.20e-1)" "unprognostic (5.10e-3)" "unprognostic (1.76e-1)" "unprognostic (1.35e-1)" "unprognostic (7.06e-2)" "unprognostic (2.19e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (5.43e-6)" "unprognostic (1.70e-2)" "unprognostic (1.07e-1)" "unprognostic (2.78e-3)" "unprognostic (6.11e-3)" DES "CMD1I, CSM1, CSM2" ENSG00000175084 Desmin P17661 2 219418377-219426735 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cancer-related genes, Cardiomyopathy, Desmin-related myopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 12603.3;intestine: 8337.1;skeletal muscle: 15949.1" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 1154.6;Skeletal myocytes: 4231.1" "Cancer enhanced" "Detected in all" "prostate cancer: 562.1;stomach cancer: 400.2" "Region enhanced" "Detected in many" "cerebral cortex: 12.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 62 "Sarcoma: 73.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "midbrain: 40.3" "CAB000034, HPA018803" Enhanced Supported "Intermediate filaments" NA NA 1600000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 32: Smooth muscle cells - Muscle contraction" 36 "Intermediate filaments" "CAB000034: , HPA018803: AB_1847616" "unprognostic (1.75e-1)" "unprognostic (1.95e-3)" "unprognostic (3.43e-2)" "unprognostic (8.76e-2)" "unprognostic (7.75e-3)" "unprognostic (6.61e-3)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (4.67e-1)" "unprognostic (3.84e-2)" "unprognostic (2.57e-1)" "unprognostic (7.43e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (3.49e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (9.25e-3)" FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1162.8;intestine: 1412.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 636.6;monocytes: 495.4;Peritubular cells: 475.9;Smooth muscle cells: 758.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 33: Non-specific - ATP binding" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 32: Smooth muscle cells - Muscle contraction" 18 "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" HSPB7 cvHSP ENSG00000173641 "Heat shock protein family B (small) member 7" Q9UBY9 1 16014028-16019594 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 4001.1;skeletal muscle: 2332.4;tongue: 1182.0" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 506.2;Skeletal myocytes: 230.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 15.8;Brain cancer: 8.8;thyroid cancer: 8.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027639 Approved Approved Nucleoplasm NA NA 130000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 43: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 15 Nucleoplasm "HPA027639: AB_10601756" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.28e-3)" "unprognostic (7.44e-3)" "unprognostic (8.35e-2)" "prognostic unfavorable (5.29e-4)" "unprognostic (1.02e-1)" "unprognostic (5.32e-2)" "unprognostic (2.47e-3)" "unprognostic (3.19e-3)" "unprognostic (6.94e-2)" "unprognostic (1.55e-1)" "unprognostic (1.20e-2)" "unprognostic (1.18e-2)" "unprognostic (1.51e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (1.26e-4)" JPH2 JP-2 ENSG00000149596 "Junctophilin 2" Q9BR39 20 44106590-44187188 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 82.4;skeletal muscle: 116.1" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 69.5;Oocytes: 39.7;Skeletal myocytes: 66.4;Smooth muscle cells: 27.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in some" HPA052646 Approved NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA052646: AB_2681899" "unprognostic (1.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.61e-4)" "unprognostic (4.71e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.06e-2)" "unprognostic (2.45e-3)" "unprognostic (6.87e-2)" "unprognostic (9.16e-2)" "unprognostic (2.57e-2)" "unprognostic (9.73e-2)" "unprognostic (4.76e-2)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-2)" KCNMB1 hslo-beta ENSG00000145936 "Potassium calcium-activated channel subfamily M regulatory beta subunit 1" Q16558 5 170374671-170389634 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 57.2;intestine: 72.5;smooth muscle: 51.1" "Cell type enriched" "Detected in many" 5 "Peritubular cells: 354.8" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;monocytes: 5.9" "Cancer enhanced" "Detected in some" "Leukemia: 3.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Smooth muscle cells - Muscle contraction" "unprognostic (2.06e-2)" "unprognostic (2.70e-4)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (8.88e-2)" "unprognostic (1.61e-2)" "unprognostic (3.46e-1)" "unprognostic (2.28e-1)" "unprognostic (4.68e-2)" "unprognostic (5.37e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.13e-6)" "unprognostic (1.08e-1)" "unprognostic (2.49e-1)" "unprognostic (4.31e-2)" "unprognostic (1.04e-2)" MYH11 "SMHC, SMMHC, SMMS-1" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3210.5;seminal vesicle: 1611.1;urinary bladder: 1980.8" "Group enriched" "Detected in many" 4 "Peritubular cells: 1636.8;Smooth muscle cells: 1301.5" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 3.4;Rhabdoid: 1.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 52.0" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 32: Smooth muscle cells - Muscle contraction" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" MYL9 "LC20, MLC2, MRLC1, MYRL2" ENSG00000101335 "Myosin light chain 9" P24844 20 36541497-36551447 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 7746.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 988.5;Breast myoepithelial cells: 1139.7;Cardiomyocytes: 925.5;Pancreatic endocrine cells: 784.5;Peritubular cells: 1866.2;Sertoli cells: 1490.4;Smooth muscle cells: 3240.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Bile duct cancer: 498.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 101.1" "HPA039262, HPA045244, HPA059197" Supported NA NA 34000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (1.15e-1)" "unprognostic (5.05e-2)" "unprognostic (2.67e-3)" "unprognostic (5.38e-2)" "unprognostic (7.17e-2)" "unprognostic (5.06e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (9.06e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (7.92e-7)" "unprognostic (1.90e-2)" "unprognostic (8.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.92e-2)" PDLIM7 ENIGMA ENSG00000196923 "PDZ and LIM domain 7" Q9NR12 5 177483394-177497606 "Predicted intracellular proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 551.2;skeletal muscle: 638.7" "Cell type enhanced" "Detected in many" "Ductal cells: 130.0;Exocrine glandular cells: 162.3;Pancreatic endocrine cells: 198.7;Peritubular cells: 219.0;Skeletal myocytes: 173.7;Smooth muscle cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 178.3;eosinophil: 121.5;neutrophil: 440.6" "Lineage enriched" "Detected in all" 9 "granulocytes: 440.6" "Low cancer specificity" "Detected in all" "Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018794, HPA048815" Approved Enhanced "Actin filaments,Focal adhesion sites" NA NA 1700000 "Cluster 21: Neutrophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Smooth muscle cells - Muscle contraction" 31 "Actin filaments, Focal adhesion sites" "HPA018794: AB_1855155, HPA048815: AB_2680530" "unprognostic (7.70e-3)" "unprognostic (3.75e-2)" "unprognostic (9.27e-3)" "prognostic unfavorable (5.45e-4)" "unprognostic (1.40e-1)" "unprognostic (3.48e-2)" "unprognostic (9.18e-3)" "prognostic unfavorable (4.07e-4)" "unprognostic (5.01e-2)" "unprognostic (3.10e-1)" "unprognostic (7.24e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (6.19e-10)" "unprognostic (6.72e-3)" "unprognostic (3.02e-1)" "unprognostic (1.93e-1)" "unprognostic (3.68e-2)" PLN "CMD1P, PLB" ENSG00000198523 Phospholamban P26678 6 118548296-118561716 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 1507.8;skeletal muscle: 489.1" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 4136.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "skin cancer: 4.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005597, HPA026900" Enhanced NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 44 "CAB005597: AB_2252716, HPA026900: AB_1855314" "unprognostic (2.49e-1)" "unprognostic (5.67e-2)" "unprognostic (1.96e-3)" "unprognostic (4.81e-2)" "unprognostic (1.20e-1)" "unprognostic (5.54e-2)" "unprognostic (2.35e-3)" "unprognostic (4.66e-2)" "unprognostic (3.97e-1)" "unprognostic (8.98e-2)" "unprognostic (8.98e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (4.11e-4)" "unprognostic (2.98e-3)" "unprognostic (1.80e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.59e-4)" TAGLN "DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10" ENSG00000149591 Transgelin Q01995 11 117199370-117207464 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 9302.4;intestine: 11317.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1542.9;Breast myoepithelial cells: 3363.1;Pancreatic endocrine cells: 2565.6;Peritubular cells: 2224.7;Sertoli cells: 1599.2;Smooth muscle cells: 7968.6" "Cancer enhanced" "Detected in all" "prostate cancer: 279.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "intermediate monocyte: 42.0;non-classical monocyte: 63.9" "Lineage enriched" "Detected in many" 11 "monocytes: 63.9" "Cancer enhanced" "Detected in all" "Bile duct cancer: 653.2;testis cancer: 743.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001447, HPA019467, HPA061657" Enhanced Approved Nucleoplasm,Microtubules,Mitochondria,Cytosol No No 6300000 "Cluster 40: Monocytes - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 "Mitochondria, Cytosol" "Nucleoplasm, Microtubules" "CAB001447: AB_564012, HPA019467: AB_1857245, HPA061657: " "unprognostic (1.36e-2)" "unprognostic (1.06e-1)" "unprognostic (3.57e-3)" "unprognostic (1.91e-1)" "unprognostic (6.58e-2)" "unprognostic (1.02e-2)" "unprognostic (2.39e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.24e-1)" "unprognostic (4.43e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.12e-7)" "unprognostic (9.58e-3)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-3)" TPM1 "C15orf13, CMH3" ENSG00000140416 "Tropomyosin 1" P09493 15 63042632-63071915 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 10276.7;skeletal muscle: 12231.4;tongue: 4981.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 14867.7;Extravillous trophoblasts: 3617.1;Pancreatic endocrine cells: 3024.1;Skeletal myocytes: 5197.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.9" "Group enriched" "Detected in all" 4 "dendritic cells: 14.1;granulocytes: 48.9;monocytes: 19.2" "Cancer enhanced" "Detected in all" "testis cancer: 3510.1" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000261, HPA009066, CAB017698, HPA047089, HPA053624" Supported Approved "Actin filaments,Cytosol" NA NA 120000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Cardiomyocytes - Muscle contraction" 7 "Actin filaments" Cytosol "CAB017698: AB_2272017, HPA000261: AB_1080339, HPA009066: AB_1080342, HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (1.07e-1)" "unprognostic (4.20e-2)" "unprognostic (1.00e-2)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-2)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (3.27e-1)" "unprognostic (1.27e-2)" "unprognostic (1.20e-1)" "unprognostic (1.66e-3)" "unprognostic (3.38e-2)" "unprognostic (1.78e-1)" "unprognostic (5.53e-2)" "prognostic unfavorable (7.30e-4)" TPM2 "AMCD1, DA1, NEM4" ENSG00000198467 "Tropomyosin 2" P07951 9 35681992-35690056 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 37641.6;tongue: 16114.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1462.1;Pancreatic endocrine cells: 1091.8;Peritubular cells: 2024.0;Sertoli cells: 1294.6;Skeletal myocytes: 5646.9;Smooth muscle cells: 3613.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 811 "plasmacytoid DC: 399.5" "Lineage enriched" "Detected in single" 922 "dendritic cells: 399.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047089, HPA053624" Approved NA NA 140000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA047089: AB_2679928, HPA053624: AB_2682210" "unprognostic (5.56e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (3.34e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-2)" "unprognostic (1.18e-3)" "unprognostic (6.56e-3)" "unprognostic (2.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.51e-10)" "unprognostic (1.43e-2)" "unprognostic (8.33e-2)" "unprognostic (5.52e-2)" "unprognostic (1.41e-2)"