Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.6;skin 1: 20.2" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 12.2;Basal respiratory cells: 7.0;Ionocytes: 6.3;Suprabasal keratinocytes: 32.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 7.8" "Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "cerebral cortex: 1.4;hippocampal formation: 1.6" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 13: Skin - Cornification" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" ABHD12 "ABHD12A, BEM46L2, C20orf22, dJ965G21.2, DKFZP434P106" ENSG00000100997 "Abhydrolase domain containing 12, lysophospholipase" Q8N2K0 20 25294742-25390835 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Cataract, Deafness, Disease variant, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026866 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 5: Enterocytes - Absorption" "HPA026866: AB_1844446" "prognostic unfavorable (3.81e-5)" "prognostic favorable (1.30e-5)" "unprognostic (1.32e-1)" "unprognostic (8.74e-2)" "unprognostic (3.67e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (7.18e-4)" "unprognostic (8.51e-2)" "unprognostic (7.91e-3)" "unprognostic (2.08e-1)" "unprognostic (4.08e-2)" "unprognostic (8.46e-2)" "unprognostic (1.36e-3)" "unprognostic (2.45e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.11e-3)" ABHD12B "BEM46L3, C14orf29" ENSG00000131969 "Abhydrolase domain containing 12B" Q7Z5M8 14 50872053-50904970 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 6.6;retina: 13.9;skin 1: 10.1" "Cell type enriched" "Detected in some" 5 "Muller glia cells: 165.0" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 1.0;neutrophil: 2.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.2" "Cancer enriched" "Detected in some" 5 "cervical cancer: 5.6" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Skin - Keratinocyte (granular)" "Region enriched" "Detected in single" 5 "thalamus: 2.1" "Low region specificity" "Detected in many" HPA002873 Uncertain Uncertain Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 38: Sub-cortical - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 10: Muller glia cells - Visual perception" Nucleoplasm "HPA002873: AB_2220573" "unprognostic (6.61e-2)" "unprognostic (3.49e-2)" "unprognostic (2.92e-3)" "unprognostic (1.99e-3)" "unprognostic (4.63e-2)" "unprognostic (1.17e-2)" "unprognostic (1.62e-2)" "unprognostic (2.09e-1)" "unprognostic (4.31e-2)" "unprognostic (6.27e-2)" "unprognostic (3.30e-1)" "unprognostic (3.35e-1)" "unprognostic (1.70e-3)" "unprognostic (3.16e-2)" "unprognostic (9.62e-2)" "unprognostic (3.18e-3)" "unprognostic (1.68e-1)" ABHD8 "FLJ11743, MGC14280, MGC2512" ENSG00000127220 "Abhydrolase domain containing 8" Q96I13 19 17292131-17310236 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 98.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.9;Early spermatids: 143.7;Late spermatids: 291.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037658, HPA058209" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA037658: AB_10672602, HPA058209: AB_2683638" "unprognostic (4.71e-3)" "unprognostic (5.06e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (7.45e-3)" "unprognostic (7.09e-2)" "unprognostic (1.96e-2)" "unprognostic (5.61e-2)" "unprognostic (9.62e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.04e-5)" "unprognostic (3.77e-1)" "unprognostic (6.36e-3)" "unprognostic (1.56e-1)" "unprognostic (3.14e-1)" "unprognostic (1.50e-1)" "unprognostic (9.24e-2)" ACER1 ASAH3 ENSG00000167769 "Alkaline ceramidase 1" Q8TDN7 19 6306142-6333612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 85.3" "Cell type enriched" "Detected in some" 6 "Suprabasal keratinocytes: 16.1" "Group enriched" "Detected in some" 7 "head and neck cancer: 1.0;melanoma: 2.2;prostate cancer: 0.6" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "T-cells: 1.2" "Cancer enhanced" "Detected in single" "prostate cancer: 1.1" "Prostate - Prostate glandular cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Skin - Cornification" "Cluster 48: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "unprognostic (1.13e-2)" "unprognostic (2.87e-4)" "unprognostic (5.04e-2)" "unprognostic (6.18e-2)" "unprognostic (8.16e-4)" "unprognostic (7.27e-4)" "unprognostic (2.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.99e-1)" "unprognostic (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.30e-5)" "unprognostic (2.11e-1)" "unprognostic (4.44e-2)" "unprognostic (4.22e-1)" "unprognostic (2.24e-1)" ACP7 "FLJ16165, PAPL, PAPL1" ENSG00000183760 "Acid phosphatase 7, tartrate resistant (putative)" Q6ZNF0 19 39083913-39111493 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.2;skin 1: 5.8" "Cell type enriched" "Detected in some" 5 "Oligodendrocytes: 10.0" "Group enriched" "Detected in some" 5 "cervical cancer: 0.8;head and neck cancer: 2.6;lung cancer: 1.4;melanoma: 1.0;urothelial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA042613 Uncertain "Secreted - unknown location" Enzyme NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Oligodendrocytes - Unknown function" "HPA042613: AB_10963214" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-3)" "unprognostic (1.92e-3)" "unprognostic (1.41e-1)" "unprognostic (3.41e-1)" "unprognostic (4.94e-3)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" "unprognostic (1.51e-5)" "unprognostic (4.36e-3)" "unprognostic (5.08e-2)" "unprognostic (2.31e-2)" "unprognostic (2.42e-1)" AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 296.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 136.2;Basal respiratory cells: 78.6;Horizontal cells: 163.0;Salivary duct cells: 68.9;Squamous epithelial cells: 72.7;Suprabasal keratinocytes: 241.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 16.4;midbrain: 15.1;pons: 18.8;spinal cord: 56.8;thalamus: 21.4" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 40000 "Cluster 13: Skin - Cornification" "Cluster 45: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "HPA000878: AB_2666127, HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: AB_2670371" "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.23e-5)" ALOX12B 12R-LOX ENSG00000179477 "Arachidonate 12-lipoxygenase, 12R type" O75342 17 8072636-8087716 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 87.3" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 11.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "basophil: 4.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.3" "Cancer enhanced" "Detected in some" "cervical cancer: 3.2" "Prostate - Prostate glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024002 Supported Supported Vesicles,Cytosol NA NA 7000 "Cluster 32: Basophils - Transcription" "Cluster 13: Skin - Cornification" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 Cytosol Vesicles "HPA024002: AB_1844757" "unprognostic (1.27e-2)" "unprognostic (1.59e-2)" "unprognostic (4.28e-3)" "unprognostic (1.38e-2)" "unprognostic (3.94e-3)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.04e-1)" "unprognostic (4.40e-2)" "unprognostic (9.55e-2)" "unprognostic (6.66e-3)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (8.01e-2)" "unprognostic (3.46e-2)" ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "skin 1: 54.5" "Cell type enriched" "Detected in some" 7 "Oocytes: 40.4" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 3.9;melanoma: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 13: Skin - Cornification" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 3 "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: AB_2732385" "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" ANKRD2 ARPP ENSG00000165887 "Ankyrin repeat domain 2" Q9GZV1 10 97572499-97583884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 62 "heart muscle: 422.8;skeletal muscle: 946.6;tongue: 791.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 193.6;Skeletal myocytes: 103.4" "Cancer enhanced" "Detected in many" "renal cancer: 4.9;testis cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 16.6" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040842, HPA040884" Enhanced Enhanced Vesicles NA NA 110000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 Vesicles "HPA040842: AB_10963794, HPA040884: AB_10969453" "unprognostic (1.27e-2)" "unprognostic (9.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-2)" "unprognostic (1.37e-1)" "unprognostic (1.61e-2)" "unprognostic (2.53e-1)" "unprognostic (5.60e-3)" "unprognostic (2.17e-1)" "unprognostic (3.12e-1)" "unprognostic (4.91e-2)" "unprognostic (2.22e-1)" "unprognostic (1.05e-2)" "unprognostic (3.69e-3)" "unprognostic (4.56e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" ANXA9 ANX31 ENSG00000143412 "Annexin A9" O76027 1 150982249-150995634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 15.5;Cholangiocytes: 57.2;Collecting duct cells: 15.6;Ductal cells: 22.0;Hepatocytes: 16.9;Proximal tubular cells: 44.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.6" "Group enriched" "Detected in many" 4 "dendritic cells: 1.6;granulocytes: 1.0;monocytes: 1.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes, Skin - Keratinocyte (granular), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA028404, HPA028698" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "Nuclear speckles, Cytosol" "HPA028404: AB_10599190, HPA028698: AB_10600227" "unprognostic (4.06e-1)" "unprognostic (1.55e-2)" "unprognostic (3.15e-3)" "unprognostic (2.08e-3)" "unprognostic (2.93e-2)" "unprognostic (4.49e-2)" "unprognostic (1.84e-2)" "unprognostic (3.39e-2)" "unprognostic (1.08e-1)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "unprognostic (2.97e-1)" "prognostic favorable (8.74e-6)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (8.99e-2)" "unprognostic (1.72e-2)" AQP9 "HsT17287, SSC1" ENSG00000103569 "Aquaporin 9" O43315 15 58138169-58185911 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 681.6" "Cell type enhanced" "Detected in some" "Hepatocytes: 277.8;Hofbauer cells: 71.4;Kupffer cells: 51.3;Macrophages: 89.1;monocytes: 342.1" "Cancer enriched" "Detected in many" 30 "liver cancer: 132.4" "Region enhanced" "Detected in many" "cerebral cortex: 28.1" "Immune cell enriched" "Detected in many" 20 "neutrophil: 1165.9" "Lineage enriched" "Detected in many" 20 "granulocytes: 1165.9" "Cancer enriched" "Detected in single" 9 "lymphoma: 9.0" "Adipose subcutaneous - Macrophages, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Hepatocytes, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Stomach - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA074762, CAB075684" Enhanced NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 18 "CAB075684: , HPA074762: AB_2732267" "unprognostic (1.91e-1)" "unprognostic (1.92e-1)" "unprognostic (7.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.24e-2)" "unprognostic (4.15e-2)" "unprognostic (1.36e-3)" "unprognostic (2.28e-2)" "unprognostic (3.82e-2)" "unprognostic (2.03e-1)" "unprognostic (4.80e-3)" "unprognostic (6.98e-2)" "prognostic unfavorable (5.72e-11)" "unprognostic (8.78e-2)" "unprognostic (1.13e-2)" "unprognostic (1.25e-1)" "unprognostic (8.39e-2)" ARFGAP2 "FLJ14576, IRZ, Zfp289, ZNF289" ENSG00000149182 "ADP ribosylation factor GTPase activating protein 2" Q8N6H7 11 47164299-47177125 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016649, HPA018152" Enhanced Supported "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Non-specific - Transcription" "Golgi apparatus" "HPA016649: AB_1844980, HPA018152: AB_1844979" "unprognostic (1.69e-2)" "unprognostic (9.11e-2)" "unprognostic (5.91e-2)" "unprognostic (3.75e-2)" "unprognostic (2.20e-2)" "unprognostic (1.12e-1)" "unprognostic (4.81e-3)" "unprognostic (1.23e-1)" "unprognostic (1.25e-1)" "unprognostic (2.41e-1)" "unprognostic (3.42e-2)" "unprognostic (7.00e-2)" "prognostic favorable (7.65e-7)" "unprognostic (2.05e-1)" "unprognostic (9.36e-2)" "unprognostic (1.06e-1)" "unprognostic (9.20e-2)" ARG1 ENSG00000118520 "Arginase 1" P05089 6 131470832-131584332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 1166.8" "Cell type enriched" "Detected in some" 23 "Hepatocytes: 1098.0" "Cancer enriched" "Detected in some" 45 "liver cancer: 167.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "neutrophil: 45.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 45.0" "Group enriched" "Detected in some" 6 "Leukemia: 1.6;liver cancer: 1.7" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Stomach - Neutrophils, Thyroid - Neutrophils" "Region enhanced" "Detected in single" "cerebellum: 2.4" "Low region specificity" "Detected in some" "HPA003595, CAB009434, HPA024006, CAB056159, CAB080011" Enhanced NA NA 9500000 "Cluster 4: Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 43: Hepatocytes - Metabolism" "CAB009434: AB_2058955, CAB056159: AB_2665582, CAB080011: , HPA003595: AB_1078190, HPA024006: AB_1844987" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-1)" "unprognostic (9.95e-2)" "unprognostic (7.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (7.55e-3)" "unprognostic (8.35e-2)" "unprognostic (1.25e-2)" "unprognostic (2.90e-2)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (1.79e-2)" ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 553.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 870.4;Hofbauer cells: 938.2;monocytes: 1587.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 270.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" Enzyme NA NA 400000 "Cluster 40: Monocytes - Innate immune response" "Cluster 30: Heart muscle - Heart development" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 29: Monocytes - Innate immune response" 1 "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" ASPHD2 FLJ39838 ENSG00000128203 "Aspartate beta-hydroxylase domain containing 2" Q6ICH7 22 26429260-26445015 "Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.0;skin 1: 10.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.8;Early spermatids: 13.6;Excitatory neurons: 13.7;Extravillous trophoblasts: 14.7;Late spermatids: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.3" "Group enriched" "Detected in many" 4 "dendritic cells: 2.2;monocytes: 5.3" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000820 Uncertain NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 65: Cerebellum - Nervous system development" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 11: Late spermatids - Unknown function" "HPA000820: AB_1078231" "unprognostic (1.12e-1)" "unprognostic (1.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.71e-1)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-2)" "unprognostic (8.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.06e-5)" "unprognostic (6.55e-2)" "unprognostic (9.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.11e-2)" ASPRV1 "FLJ25084, SASPase, Taps" ENSG00000244617 "Aspartic peptidase retroviral like 1" Q53RT3 2 69960089-69961631 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "skin 1: 410.4" "Cell type enhanced" "Detected in some" "Oligodendrocytes: 3.8;Spermatogonia: 3.3;Suprabasal keratinocytes: 7.4" "Group enriched" "Detected in many" 8 "head and neck cancer: 23.1;melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 10.8" "Lineage enriched" "Detected in many" 10 "granulocytes: 10.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 5.5" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "HPA034809, HPA034810" Enhanced Approved Cytosol NA NA 150000 "Cluster 35: Neutrophils - Protein binding" "Cluster 82: Skin - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" Cytosol "HPA034809: AB_2674343, HPA034810: AB_10601456" "unprognostic (4.75e-4)" "unprognostic (1.90e-3)" "unprognostic (2.34e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (1.17e-2)" "unprognostic (1.93e-3)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (4.19e-3)" "unprognostic (1.27e-1)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.84e-2)" "unprognostic (2.43e-2)" ATG2A "BLTP4A, KIAA0404" ENSG00000110046 "Autophagy related 2A" Q2TAZ0 11 64894546-64917211 "Predicted intracellular proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 67.6;Syncytiotrophoblasts: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 17.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 17.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038715 Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" Transport NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 56: Non-specific - Unknown function" "Cluster 12: Non-specific - Vasculature" "Cluster 24: Non-specific - Unknown function" "Cluster 74: Neutrophils - Degranulation" 7 Vesicles Nucleoplasm "HPA038715: AB_10673474" "unprognostic (3.05e-2)" "unprognostic (2.33e-1)" "unprognostic (7.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.42e-1)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.79e-5)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (3.37e-1)" "unprognostic (1.15e-1)" ATG9B "APG9L2, FLJ14885, NOS3AS, SONE" ENSG00000181652 "Autophagy related 9B" Q674R7 7 151012209-151024499 "Metabolic proteins, Predicted membrane proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.0;placenta: 4.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 28.5;Early spermatids: 63.1;Late spermatids: 26.6;Syncytiotrophoblasts: 147.9" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "unprognostic (1.59e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (1.53e-3)" "unprognostic (1.05e-3)" "unprognostic (2.79e-3)" "unprognostic (6.66e-2)" "unprognostic (2.38e-3)" "unprognostic (6.76e-2)" "unprognostic (2.02e-1)" "unprognostic (5.06e-2)" "unprognostic (2.08e-6)" "unprognostic (2.82e-2)" "unprognostic (2.70e-2)" "unprognostic (6.34e-2)" "unprognostic (2.63e-1)" BSPRY FLJ20150 ENSG00000119411 "B-box and SPRY domain containing" Q5W0U4 9 113349541-113371233 "Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 432.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 60.2;Ductal cells: 58.7;Exocrine glandular cells: 67.9;Serous glandular cells: 123.8;Suprabasal keratinocytes: 59.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 21 "dendritic cells: 4.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Mast cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebellum: 4.8" "HPA042889, HPA077485" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Serous glandular cells - Salivary secretion" Nucleoplasm Cytosol "HPA042889: AB_10795515, HPA077485: " "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "unprognostic (1.18e-1)" "unprognostic (2.20e-3)" "unprognostic (1.68e-1)" "unprognostic (2.10e-3)" "unprognostic (4.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (2.28e-1)" "unprognostic (1.95e-2)" "prognostic favorable (4.56e-14)" "unprognostic (1.15e-3)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (1.70e-1)" BTBD16 "C10orf87, Em:AC061711.1, FLJ25359" ENSG00000138152 "BTB domain containing 16" Q32M84 10 122271296-122338159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 8.1;testis: 7.6;urinary bladder: 19.5" "Group enriched" "Detected in some" 11 "Early spermatids: 127.2;Late spermatids: 79.0" "Cancer enriched" "Detected in many" 14 "urothelial cancer: 18.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 4.2;pancreatic cancer: 5.1" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040529, HPA057638" Uncertain Uncertain Nucleoli,Cytosol Yes NA "Cluster 21: Testis - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 11: Late spermatids - Unknown function" Nucleoli Cytosol "HPA040529: AB_2677022, HPA057638: " "unprognostic (1.41e-4)" "unprognostic (1.33e-1)" "unprognostic (5.97e-2)" "unprognostic (5.98e-3)" "unprognostic (2.08e-1)" "unprognostic (2.09e-3)" "unprognostic (2.88e-1)" "unprognostic (4.54e-2)" "unprognostic (1.76e-1)" "unprognostic (6.85e-2)" "unprognostic (2.48e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "unprognostic (9.12e-2)" "unprognostic (9.44e-3)" BTC ENSG00000174808 Betacellulin P35070 4 74744759-74794523 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 22.1;Granulosa cells: 17.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 8.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.7" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" "Growth factor" NA NA 314000 "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Ciliated cells - Cilium assembly" 7 "unprognostic (7.36e-2)" "unprognostic (4.99e-2)" "unprognostic (7.04e-2)" "unprognostic (7.76e-3)" "unprognostic (3.87e-3)" "unprognostic (1.01e-3)" "unprognostic (1.05e-1)" "unprognostic (7.17e-3)" "unprognostic (2.68e-2)" "unprognostic (8.81e-2)" "unprognostic (1.50e-2)" "unprognostic (5.35e-1)" "prognostic favorable (6.10e-5)" "unprognostic (2.33e-1)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (2.31e-3)" C10orf95 FLJ14280 ENSG00000120055 "Chromosome 10 open reading frame 95" 10 102449837-102451543 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 9.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 35.4;Oocytes: 29.4;Rod photoreceptor cells: 15.2;Syncytiotrophoblasts: 36.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in single" "Secreted - unknown location" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 39: Retina & Testis - Cilium" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" "unprognostic (2.31e-1)" "unprognostic (7.76e-3)" "unprognostic (3.19e-1)" "unprognostic (5.62e-3)" "unprognostic (4.02e-1)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (5.98e-2)" "unprognostic (1.50e-2)" "unprognostic (1.01e-1)" "unprognostic (4.42e-2)" "unprognostic (2.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (2.14e-1)" "unprognostic (1.22e-2)" "unprognostic (4.80e-3)" C1orf68 "LEP7, XP32" ENSG00000198854 "Chromosome 1 open reading frame 68" Q5T750 1 152719522-152720470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 659.7" "Cell type enriched" "Detected in some" 10 "Suprabasal keratinocytes: 35.6" "Group enriched" "Detected in some" 13 "head and neck cancer: 2.4;melanoma: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA057942 Approved "Plasma membrane,Cytosol" NA NA 220000 "Cluster 82: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA057942: " "unprognostic (1.73e-1)" "unprognostic (7.46e-2)" "unprognostic (9.34e-2)" C2CD2 "C21orf25, C21orf258, DKFZP586F0422, TMEM24L" ENSG00000157617 "C2 calcium dependent domain containing 2" Q9Y426 21 41885112-41954018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 122.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 50.4;Cone photoreceptor cells: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030922, HPA030924" Enhanced Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 25: Bipolar cells - Visual perception" Nucleoplasm "HPA030922: AB_2673660, HPA030924: AB_10669873" "unprognostic (3.02e-3)" "unprognostic (3.69e-2)" "unprognostic (2.21e-2)" "unprognostic (9.63e-2)" "unprognostic (3.15e-3)" "unprognostic (2.93e-2)" "unprognostic (2.39e-2)" "unprognostic (3.44e-2)" "unprognostic (3.00e-2)" "unprognostic (4.39e-2)" "unprognostic (2.43e-1)" "unprognostic (2.38e-1)" "prognostic unfavorable (7.68e-5)" "unprognostic (1.99e-1)" "unprognostic (4.56e-2)" "unprognostic (1.06e-2)" "unprognostic (1.48e-1)" C5orf46 "AP-64, MGC23985, SSSP1" ENSG00000178776 "Chromosome 5 open reading frame 46" Q6UWT4 5 147880726-147906538 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "salivary gland: 176.1;skin 1: 109.5" "Group enriched" "Detected in many" 8 "Early spermatids: 288.8;Late spermatids: 207.1;Mucus glandular cells: 101.8;Serous glandular cells: 247.4" "Cancer enhanced" "Detected in many" "renal cancer: 8.3" "Group enriched" "Detected in some" 7 "cerebellum: 4.8;choroid plexus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 61.6" "Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058999, HPA079692" Supported Approved "Nuclear speckles,Mitochondria" "Secreted in other tissues" "No annotated function" NA NA 54000 "Cluster 13: Skin - Cornification" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 75: Serous glandular cells - Salivary secretion" 11 "Nuclear speckles" Mitochondria "HPA058999: , HPA079692: " "unprognostic (1.72e-1)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.26e-4)" "unprognostic (9.75e-3)" "unprognostic (2.95e-3)" "unprognostic (1.69e-3)" "unprognostic (1.99e-2)" "unprognostic (3.08e-2)" "unprognostic (2.22e-1)" "unprognostic (4.96e-2)" "unprognostic (2.86e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.75e-9)" "unprognostic (6.48e-3)" "unprognostic (3.47e-2)" "unprognostic (6.01e-2)" "unprognostic (2.79e-2)" C6orf15 STG ENSG00000204542 "Chromosome 6 open reading frame 15" Q6UXA7 6 31111223-31112575 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 5.3;lymphoid tissue: 3.4;skin 1: 6.5" "Cell type enriched" "Detected in some" 8 "Breast glandular cells: 75.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 20.9;colorectal cancer: 26.9;Esophageal cancer: 22.8" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA001436 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 13: Skin - Cornification" "Cluster 32: Non-specific - Cell proliferation" "Cluster 17: Breast glandular cells - Lactation" 5 "HPA001436: AB_2243752" "unprognostic (2.73e-2)" "unprognostic (5.39e-2)" "unprognostic (1.46e-2)" "unprognostic (3.19e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.35e-1)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.72e-1)" "unprognostic (1.90e-1)" "unprognostic (1.34e-3)" C8orf74 ENSG00000171060 "Chromosome 8 open reading frame 74" Q6P047 8 10672628-10700590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 166 "testis: 16.6" "Group enriched" "Detected in some" 117 "Early spermatids: 158.2;Late spermatids: 390.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA027986 Uncertain Uncertain Nucleoplasm NA NA "Cluster 10: Testis - Spermatid development" "Cluster 11: Late spermatids - Unknown function" 4 Nucleoplasm "HPA027986: AB_10600762" "unprognostic (4.24e-2)" "unprognostic (5.62e-2)" "unprognostic (4.68e-2)" "unprognostic (5.54e-2)" "unprognostic (2.37e-2)" "unprognostic (1.56e-4)" "unprognostic (6.82e-2)" "unprognostic (2.20e-2)" C8orf90 ENSG00000226490 "Chromosome 8 open reading frame 90" 8 141514638-141518737 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enriched" "Detected in some" 5 "testis: 9.6" "Group enriched" "Detected in some" 7 "Early spermatids: 269.5;Late spermatids: 74.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 9.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 18: Early spermatids - Unknown function" CALML5 CLSP ENSG00000178372 "Calmodulin like 5" Q9NZT1 10 5498697-5499570 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 2962.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 179.3;Breast myoepithelial cells: 135.5;Mucus glandular cells: 81.4;Serous glandular cells: 540.1;Suprabasal keratinocytes: 282.4" "Group enriched" "Detected in many" 6 "breast cancer: 97.6;cervical cancer: 189.1;head and neck cancer: 206.0;melanoma: 222.1;urothelial cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 184.2;Esophageal cancer: 54.5" "Breast - Breast glandular cells (progenitors), Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA040725 Enhanced Approved "Plasma membrane,Cytosol" NA NA 48000000 "Cluster 13: Skin - Cornification" "Cluster 70: DU4475 - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" "Plasma membrane, Cytosol" "HPA040725: AB_10793863" "unprognostic (7.68e-3)" "unprognostic (5.06e-3)" "unprognostic (5.64e-2)" "prognostic favorable (2.59e-5)" "unprognostic (4.82e-2)" "unprognostic (2.67e-1)" "unprognostic (1.37e-1)" "unprognostic (8.27e-2)" "unprognostic (1.14e-1)" "unprognostic (2.79e-1)" "unprognostic (1.71e-1)" "unprognostic (4.99e-2)" CAPN15 SOLH ENSG00000103326 "Calpain 15" O75808 16 527712-554636 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Deafness, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 4.7;neutrophil: 16.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.5" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011960, HPA074218" Approved Approved Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 66: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 6 Nucleoplasm "HPA011960: AB_10610556, HPA074218: " "unprognostic (4.11e-2)" "unprognostic (1.63e-1)" "unprognostic (1.14e-1)" "unprognostic (2.66e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-2)" "unprognostic (1.54e-3)" "unprognostic (8.31e-3)" "unprognostic (1.32e-1)" "unprognostic (1.24e-1)" "unprognostic (1.86e-1)" "unprognostic (4.02e-2)" "unprognostic (2.53e-3)" "unprognostic (2.54e-3)" "unprognostic (5.91e-2)" "unprognostic (1.83e-1)" "unprognostic (9.23e-3)" CCDC120 JM11 ENSG00000147144 "Coiled-coil domain containing 120" Q96HB5 X 49053572-49069857 "Cancer-related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.9;skin 1: 28.3" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000561 Uncertain Mitochondria NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 90 Mitochondria "HPA000561: AB_2244190" "unprognostic (1.65e-1)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (7.59e-3)" "unprognostic (1.80e-3)" "unprognostic (1.08e-2)" "unprognostic (2.59e-3)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.72e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (4.85e-2)" "unprognostic (2.64e-2)" "unprognostic (3.82e-3)" "unprognostic (4.54e-3)" "unprognostic (2.34e-3)" CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811991-29824312 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.3;placenta: 29.8" "Cell type enriched" "Detected in many" 14 "Extravillous trophoblasts: 2071.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm Yes Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 4: Extravillous trophoblasts - Unknown function" 7 Nucleoplasm "CAB000308: , CAB016682: AB_1614564, HPA018169: AB_1847384" "unprognostic (2.90e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-3)" "prognostic unfavorable (6.35e-6)" "unprognostic (5.78e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (3.89e-5)" "unprognostic (1.26e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (3.29e-2)" "unprognostic (7.07e-2)" "unprognostic (1.11e-16)" "unprognostic (5.61e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-2)" "unprognostic (1.46e-1)" CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 241.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 78: Testis - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 5 "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: AB_2276050, CAB047311: , HPA002382: AB_1846370, HPA074334: " "unprognostic (4.65e-2)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (8.72e-2)" "unprognostic (2.84e-1)" "unprognostic (5.73e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (2.20e-1)" "unprognostic (3.11e-1)" "unprognostic (3.83e-2)" "unprognostic (2.09e-2)" "unprognostic (3.06e-2)" "unprognostic (3.02e-2)" "unprognostic (8.87e-3)" "unprognostic (9.68e-2)" "unprognostic (7.82e-3)" "unprognostic (3.33e-2)" CDSN D6S586E ENSG00000204539 Corneodesmosin 6 31115087-31120446 "Human disease related genes, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 104 "skin 1: 674.3" "Group enriched" "Detected in some" 4 "Cholangiocytes: 3.8;Gastric mucus-secreting cells: 1.8;Glandular and luminal cells: 6.1;Suprabasal keratinocytes: 3.4" "Group enriched" "Detected in some" 8 "head and neck cancer: 2.4;melanoma: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 2.0;head and neck cancer: 1.4" "Skin - Keratinocyte (granular)" "Region enhanced" "Detected in some" "cerebral cortex: 1.5" "Not detected" "Not detected" "HPA044730, HPA054184" Enhanced "Secreted in other tissues" NA NA "Cluster 82: Skin - Keratinization" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA044730: AB_10964923, HPA054184: AB_2682409" "unprognostic (1.46e-1)" "unprognostic (6.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (8.80e-2)" "unprognostic (8.13e-2)" "unprognostic (3.92e-4)" "unprognostic (3.92e-3)" "unprognostic (1.74e-4)" "unprognostic (6.34e-2)" "unprognostic (2.75e-1)" "unprognostic (2.22e-1)" CES4A "CES8, FLJ37464" ENSG00000172824 "Carboxylesterase 4A" Q5XG92 16 66988589-67010417 "Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 17.4;skin 1: 13.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 44.7;Ciliated cells: 49.1;Excitatory neurons: 51.8;Oligodendrocytes: 35.0;Spermatocytes: 32.6" "Cancer enhanced" "Detected in many" "renal cancer: 5.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA035701 Approved Approved Cytosol "Secreted - unknown location" Enzyme NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 13: Skin - Cornification" "Cluster 34: Non-specific - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 17: Breast glandular cells - Lactation" Cytosol "HPA035701: AB_10696357" "unprognostic (6.34e-2)" "unprognostic (2.09e-1)" "unprognostic (3.18e-1)" "unprognostic (3.26e-2)" "unprognostic (1.99e-1)" "unprognostic (6.20e-2)" "unprognostic (2.12e-2)" "unprognostic (2.04e-2)" "unprognostic (5.78e-3)" "unprognostic (3.93e-2)" "unprognostic (2.02e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (2.35e-6)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-3)" CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 54.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 177.3;Alveolar cells type 2: 57.9;Distal enterocytes: 113.1;Mesothelial cells: 81.6;Proximal enterocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 3 "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: AB_10600208, HPA027587: AB_10601884, HPA027657: AB_10611527" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.74e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (4.61e-1)" "unprognostic (2.11e-2)" "unprognostic (2.96e-3)" "unprognostic (7.10e-2)" "prognostic favorable (5.84e-10)" "unprognostic (2.66e-1)" "unprognostic (3.00e-1)" "unprognostic (8.28e-2)" "unprognostic (2.10e-2)" CHRM4 ENSG00000180720 "Cholinergic receptor muscarinic 4" P08173 11 46383789-46391776 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.0;intestine: 5.9;lymphoid tissue: 14.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "basal ganglia: 44.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 22.1" "CAB022444, HPA072083" Enhanced Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 77: Plasma cells - Protein processing" 2 "Golgi apparatus" Nucleoplasm "CAB022444: , HPA072083: " "unprognostic (7.11e-2)" "unprognostic (3.79e-1)" "unprognostic (5.31e-2)" "unprognostic (7.38e-2)" "unprognostic (8.63e-3)" "unprognostic (1.38e-1)" "unprognostic (6.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (2.96e-3)" "unprognostic (4.08e-3)" "unprognostic (5.02e-2)" "unprognostic (3.83e-2)" "unprognostic (3.64e-1)" "unprognostic (1.71e-1)" "unprognostic (3.56e-1)" "unprognostic (5.08e-2)" CHRNE ACHRE ENSG00000108556 "Cholinergic receptor nicotinic epsilon subunit" Q04844 17 4897771-4934438 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "heart muscle: 53.4;pituitary gland: 26.8" "Cell type enhanced" "Detected in many" "granulocytes: 36.9;Late spermatids: 166.6;Oocytes: 55.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.5" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "prostate cancer: 1.3" "Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "basal ganglia: 8.3" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 15: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 36: Late spermatids - Unknown function" "unprognostic (2.00e-3)" "unprognostic (1.56e-1)" "unprognostic (3.94e-2)" "unprognostic (4.35e-3)" "unprognostic (6.55e-2)" "unprognostic (2.27e-3)" "unprognostic (7.80e-4)" "unprognostic (7.75e-2)" "unprognostic (3.24e-1)" "unprognostic (1.34e-1)" "unprognostic (3.69e-2)" "unprognostic (6.58e-2)" "unprognostic (8.42e-4)" "unprognostic (1.39e-3)" "unprognostic (1.26e-1)" "unprognostic (5.83e-2)" "unprognostic (5.70e-2)" CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.9;stomach 1: 15.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 337.6;Gastric mucus-secreting cells: 61.9;Paneth cells: 183.6;Proximal enterocytes: 99.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "choroid plexus: 4.6" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 5: Enterocytes - Absorption" 1 Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 296.4;urinary bladder: 291.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2807.8;Glandular and luminal cells: 2344.4;Ionocytes: 1646.0;Paneth cells: 2199.5;Proximal enterocytes: 1639.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 992.2" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 14 "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" CLN8 "C8orf61, EPMR, FLJ39417, TLCD6" ENSG00000182372 "CLN8 transmembrane ER and ERGIC protein" Q9UBY8 8 1755778-1801711 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 352.7;Langerhans cells: 160.1;Syncytiotrophoblasts: 140.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 76.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 76.7" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 28: Dendritic cells - Antigen presentation" "unprognostic (5.86e-2)" "unprognostic (1.95e-2)" "unprognostic (6.40e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (4.05e-3)" "unprognostic (1.21e-1)" "unprognostic (3.45e-1)" "unprognostic (3.03e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-3)" "unprognostic (1.83e-1)" "prognostic favorable (4.36e-8)" "unprognostic (1.36e-1)" "unprognostic (1.70e-1)" "unprognostic (6.24e-2)" "unprognostic (8.38e-2)" CNFN PLAC8L2 ENSG00000105427 Cornifelin Q9BYD5 19 42387019-42390297 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 925.8;esophagus: 3006.5;vagina: 1399.2" "Cell type enriched" "Detected in many" 5 "Suprabasal keratinocytes: 1633.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 367.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 11 "memory B-cell: 61.4;naive B-cell: 70.6" "Lineage enriched" "Detected in many" 12 "B-cells: 70.6" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049073, HPA053997" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 18: Non-specific - Translation" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 10 Microtubules "Cytokinetic bridge" "HPA049073: AB_2680620, HPA053997: AB_2682337" "unprognostic (5.08e-2)" "unprognostic (4.21e-3)" "unprognostic (2.52e-1)" "unprognostic (7.22e-2)" "unprognostic (3.15e-2)" "unprognostic (8.35e-3)" "unprognostic (6.04e-2)" "unprognostic (2.06e-3)" "unprognostic (3.52e-1)" "unprognostic (9.44e-2)" "unprognostic (1.39e-1)" "unprognostic (8.37e-2)" "unprognostic (8.42e-2)" "unprognostic (4.83e-2)" "unprognostic (7.77e-3)" "prognostic favorable (4.02e-5)" "unprognostic (2.45e-1)" CORO2A "IR10, WDR2" ENSG00000106789 "Coronin 2A" Q92828 9 98120975-98192637 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 48.2;Club cells: 48.2;Distal enterocytes: 79.2;Ionocytes: 48.6;Proximal enterocytes: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 11.4;monocytes: 7.8;T-cells: 11.9" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041161, HPA041302" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 45: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 3 "Plasma membrane, Cytosol" "HPA041161: AB_10795537, HPA041302: AB_10794195" "unprognostic (4.49e-3)" "unprognostic (3.44e-2)" "unprognostic (3.14e-1)" "unprognostic (1.78e-1)" "unprognostic (3.39e-3)" "unprognostic (1.64e-1)" "unprognostic (3.73e-2)" "unprognostic (5.73e-2)" "unprognostic (2.79e-1)" "unprognostic (1.52e-1)" "unprognostic (4.50e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" "unprognostic (6.40e-3)" CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 150.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 230.9;Glandular and luminal cells: 227.4;granulocytes: 410.2;Kupffer cells: 277.8;Sertoli cells: 315.5;Syncytiotrophoblasts: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.1;intermediate monocyte: 14.5;myeloid DC: 16.7;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 5 "dendritic cells: 16.7;monocytes: 21.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Pancreas - Macrophages, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 7: Adipose tissue - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" CRCT1 "C1orf42, NICE-1" ENSG00000169509 "Cysteine rich C-terminal 1" Q9UGL9 1 152514482-152516008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 563.1;esophagus: 1771.3;vagina: 840.7" "Cell type enriched" "Detected in some" 18 "Suprabasal keratinocytes: 1012.4" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 68.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 6.6;cervical cancer: 3.7;head and neck cancer: 5.5" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 46 "unprognostic (3.01e-2)" "unprognostic (6.92e-2)" "unprognostic (2.86e-2)" "unprognostic (3.30e-1)" "prognostic unfavorable (7.03e-4)" "unprognostic (1.56e-2)" "unprognostic (1.46e-1)" CSNK2A2 "CK2alpha', CSNK2A1" ENSG00000070770 "Casein kinase 2 alpha 2" P19784 16 58157907-58198106 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 109.6" "Group enriched" "Detected in all" 4 "Early spermatids: 153.6;Late spermatids: 310.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 92000 "Cluster 41: Basophils - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 11: Late spermatids - Unknown function" 7 "unprognostic (9.49e-2)" "unprognostic (1.87e-1)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.40e-5)" "prognostic unfavorable (1.80e-4)" "unprognostic (6.84e-3)" "unprognostic (2.93e-3)" "unprognostic (2.40e-1)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (2.06e-3)" "unprognostic (7.07e-2)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 172.7;skin 1: 421.1" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 541.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 45: Eosinophils - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 14 "Nucleoplasm, Cytosol" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 338.6" "Cell type enriched" "Detected in all" 5 "Alveolar cells type 2: 1759.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 209.6;intermediate monocyte: 138.1;memory B-cell: 83.8;myeloid DC: 184.0;naive B-cell: 56.3;non-classical monocyte: 95.3" "Group enriched" "Detected in all" 5 "B-cells: 83.8;dendritic cells: 184.0;monocytes: 209.6" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" Enzyme NA NA 8700000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 47: Spleen - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 2 "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" CYP4F22 FLJ39501 ENSG00000171954 "Cytochrome P450 family 4 subfamily F member 22" Q6NT55 19 15508525-15552317 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.3;skin 1: 56.8;vagina: 22.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 53.8;Breast glandular cells: 8.5;monocytes: 8.9;Prostatic glandular cells: 11.1;Suprabasal keratinocytes: 31.2" "Group enriched" "Detected in many" 7 "breast cancer: 4.5;head and neck cancer: 5.7;liver cancer: 8.5;melanoma: 4.5;urothelial cancer: 13.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "intermediate monocyte: 6.1;MAIT T-cell: 4.3;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 8 "monocytes: 14.2;T-cells: 4.3" "Cancer enriched" "Detected in some" 31 "Bone cancer: 42.8" "Lung - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA058960 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 13: Skin - Cornification" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 3: Basal prostatic cells - Lipid metabolism" 4 "HPA058960: AB_2683862" "unprognostic (2.32e-3)" "unprognostic (1.17e-2)" "unprognostic (6.81e-2)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (7.02e-2)" "unprognostic (1.30e-1)" "unprognostic (2.43e-1)" "unprognostic (3.33e-1)" "unprognostic (1.89e-2)" "unprognostic (9.33e-2)" "unprognostic (3.00e-2)" "unprognostic (2.21e-5)" "unprognostic (8.10e-2)" "unprognostic (3.16e-1)" "unprognostic (7.25e-3)" "unprognostic (2.03e-2)" CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137225174-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "esophagus: 89.7" "Cell type enriched" "Detected in many" 6 "Suprabasal keratinocytes: 531.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.0" "Lineage enriched" "Detected in single" 6 "monocytes: 1.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 396 "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" DDA1 "C19orf58, MGC2594, PCIA1" ENSG00000130311 "DET1 and DDB1 associated 1" Q9BW61 19 17309518-17323298 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 349.2;Late spermatids: 191.5;Syncytiotrophoblasts: 272.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042134, HPA055272" Approved Approved Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 33: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 8 "Nucleoplasm, Nucleoli" "HPA042134: AB_10794169, HPA055272: AB_2682767" "unprognostic (1.30e-1)" "unprognostic (6.35e-3)" "unprognostic (3.13e-2)" "unprognostic (1.49e-3)" "unprognostic (5.38e-2)" "unprognostic (1.26e-2)" "unprognostic (3.41e-2)" "unprognostic (4.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.55e-2)" "unprognostic (1.47e-1)" "unprognostic (8.55e-2)" "unprognostic (1.48e-1)" "unprognostic (4.38e-2)" "unprognostic (6.33e-2)" "unprognostic (1.45e-1)" "unprognostic (3.15e-3)" DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 459.3;breast: 129.3;liver: 321.2;skin 1: 146.7" "Cell type enhanced" "Detected in many" "Early spermatids: 277.3;Hepatocytes: 103.0;Late spermatids: 95.1;Spermatocytes: 56.1;Spermatogonia: 46.5" "Cancer enhanced" "Detected in many" "liver cancer: 19.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 138.1;neutrophil: 350.5" "Lineage enriched" "Detected in many" 16 "granulocytes: 350.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophil_2, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 30.0" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 74: Neutrophils - Degranulation" "Vesicles, Cytosol" "HPA013351: AB_1847630" "unprognostic (2.28e-1)" "unprognostic (3.69e-1)" "unprognostic (9.38e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.63e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "unprognostic (7.59e-2)" "unprognostic (4.46e-1)" "unprognostic (4.12e-3)" "unprognostic (2.87e-1)" "unprognostic (2.99e-1)" "unprognostic (1.49e-7)" "unprognostic (2.03e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (5.60e-2)" DLX6 ENSG00000006377 "Distal-less homeobox 6" P56179 7 97005553-97011040 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.7;testis: 5.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 32.3;Early spermatids: 28.2;Extravillous trophoblasts: 73.3;Glandular and luminal cells: 27.0;Oocytes: 86.0;Syncytiotrophoblasts: 18.8" "Cancer enriched" "Detected in many" 8 "endometrial cancer: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 17.8" "Colon - Enteric glia cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 31.1;olfactory bulb: 35.6" "HPA030608, HPA061460" Uncertain Approved "Nuclear bodies" NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 4: Extravillous trophoblasts - Unknown function" "Nuclear bodies" "HPA030608: AB_10600867, HPA061460: AB_2684529" "unprognostic (7.50e-2)" "unprognostic (1.91e-1)" "unprognostic (5.19e-2)" "unprognostic (8.06e-2)" "unprognostic (8.16e-2)" "unprognostic (3.05e-1)" "unprognostic (4.32e-2)" "unprognostic (2.51e-1)" "unprognostic (2.86e-1)" "unprognostic (6.56e-2)" "unprognostic (8.09e-2)" "unprognostic (1.12e-7)" "unprognostic (5.60e-2)" "unprognostic (1.99e-1)" "unprognostic (5.58e-2)" "unprognostic (8.12e-2)" DYNLRB1 "DNCL2A, DNLC2A, ROBLD1" ENSG00000125971 "Dynein light chain roadblock-type 1" Q9NP97 20 34516395-34540958 "Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 688.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009845 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Non-specific - Basic cellular processes" 6 "CAB009845: AB_2093671" "unprognostic (2.23e-1)" "unprognostic (7.60e-3)" "unprognostic (5.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (6.44e-4)" "unprognostic (9.10e-2)" "unprognostic (3.41e-2)" "unprognostic (7.79e-2)" "unprognostic (1.71e-1)" "unprognostic (2.11e-1)" "unprognostic (7.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.00e-1)" ECM1 ENSG00000143369 "Extracellular matrix protein 1" Q16610 1 150508062-150513789 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Biomineralization, Mineral balance, Osteogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 472.5;esophagus: 1332.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 105.7;Fibroblasts: 113.6;Melanocytes: 91.0;Suprabasal keratinocytes: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 178.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (granular), Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027241, HPA076029" Enhanced Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" "Developmental protein" NA NA 8700000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Suprabasal keratinocytes - Cornification" 27 Cytosol Nucleoplasm "HPA027241: AB_1847976, HPA076029: " "unprognostic (2.89e-2)" "unprognostic (1.17e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-2)" "unprognostic (1.09e-1)" "unprognostic (6.79e-3)" "unprognostic (8.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.90e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.33e-2)" "prognostic unfavorable (1.51e-9)" "unprognostic (1.23e-2)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.20e-5)" EIF4H "KIAA0038, WBSCR1, WSCR1" ENSG00000106682 "Eukaryotic translation initiation factor 4H" Q15056 7 74174231-74197122 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Late spermatids: 2928.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030542 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 750000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 3 Cytosol "Nucleoplasm, Nuclear bodies" "HPA030542: AB_10601368" "unprognostic (2.83e-1)" "unprognostic (9.50e-2)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (3.89e-4)" "prognostic unfavorable (2.15e-4)" "unprognostic (1.61e-2)" "unprognostic (2.72e-3)" "unprognostic (1.79e-1)" "unprognostic (2.99e-2)" "unprognostic (1.72e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-2)" "unprognostic (3.04e-1)" "unprognostic (2.23e-1)" "unprognostic (5.68e-2)" "unprognostic (1.27e-2)" ELMOD1 DKFZp547C176 ENSG00000110675 "ELMO domain containing 1" Q8N336 11 107591091-107666779 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 53.2;pituitary gland: 21.1;retina: 31.6;skin 1: 28.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 27.4;Excitatory neurons: 122.0;Horizontal cells: 30.2;Inhibitory neurons: 99.5;Oligodendrocyte precursor cells: 75.9" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 26.2" "Kidney - Proximal tubular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038434, HPA038435" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 8: Neurons - Neuronal signaling" Nucleoplasm "Vesicles, Cytosol" "HPA038434: AB_10794324, HPA038435: AB_10795575" "unprognostic (2.74e-1)" "unprognostic (1.72e-4)" "unprognostic (2.58e-2)" "unprognostic (9.13e-2)" "unprognostic (3.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.34e-1)" "unprognostic (6.59e-3)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (6.29e-2)" "unprognostic (9.44e-2)" "unprognostic (1.34e-4)" "unprognostic (1.91e-2)" "unprognostic (3.15e-1)" "unprognostic (4.21e-2)" "unprognostic (1.39e-1)" ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 344.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 59: Suprabasal keratinocytes - Cornification" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: AB_2683173" "unprognostic (5.23e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" ELOVL7 FLJ23563 ENSG00000164181 "ELOVL fatty acid elongase 7" A1L3X0 5 60751791-60844274 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Microglial cells: 181.6;Oligodendrocytes: 84.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.9;neutrophil: 1.3" "Lineage enriched" "Detected in single" 17 "granulocytes: 1.9" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036337 Approved NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Oligodendrocytes - Unknown function" 11 "HPA036337: AB_10670797" "unprognostic (6.34e-2)" "unprognostic (1.96e-2)" "unprognostic (1.51e-2)" "prognostic unfavorable (3.87e-5)" "unprognostic (3.84e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (1.79e-1)" "unprognostic (2.37e-1)" "unprognostic (2.10e-1)" "prognostic favorable (1.54e-9)" "unprognostic (6.95e-2)" "unprognostic (1.01e-3)" "unprognostic (2.94e-1)" "unprognostic (6.30e-3)" ENSG00000188897 ENSG00000188897 "Novel lipoprotein amino terminal region containing protein" 16 11359845-11527247 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.1" "Cell type enhanced" "Detected in some" "Early spermatids: 5.3;Langerhans cells: 6.5;Mucus glandular cells: 13.9;Oligodendrocyte precursor cells: 5.7;Salivary duct cells: 5.1;Skeletal myocytes: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "neutrophil: 3.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 3.5" "Cancer enhanced" "Detected in some" "Myeloma: 3.8" "Adipose visceral - Neutrophils, Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA042154 Uncertain NA NA "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 74: Neutrophils - Degranulation" "HPA042154: AB_2677877" "unprognostic (4.69e-2)" "unprognostic (3.80e-2)" "unprognostic (7.24e-2)" "unprognostic (5.91e-2)" "unprognostic (1.21e-3)" "unprognostic (7.91e-2)" "unprognostic (9.18e-2)" "unprognostic (6.08e-2)" "unprognostic (8.04e-2)" "unprognostic (5.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.04e-1)" "unprognostic (3.72e-6)" "unprognostic (3.18e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-1)" "unprognostic (4.33e-5)" ENSG00000236543 ENSG00000236543 "Novel beta-lactoglobulin-like protein" 9 135604345-135619893 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 31 "skin 1: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 13: Skin - Cornification" "Cluster 34: Testis cancer - Unknown function" EPN3 "FLJ20778, MGC129899" ENSG00000049283 "Epsin 3" Q9H201 17 50532682-50543750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.9;stomach 1: 36.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 76.2;Distal enterocytes: 31.4;Gastric mucus-secreting cells: 41.9;Squamous epithelial cells: 32.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 48.6" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055546, HPA063224" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" Vesicles Nucleoplasm "HPA055546: AB_2682844, HPA063224: AB_2684964" "unprognostic (1.91e-2)" "unprognostic (1.99e-2)" "unprognostic (2.41e-1)" "unprognostic (2.91e-2)" "unprognostic (1.25e-3)" "unprognostic (2.06e-1)" "unprognostic (5.70e-3)" "unprognostic (7.62e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (6.66e-3)" "unprognostic (1.00e-2)" "prognostic favorable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (4.90e-1)" "unprognostic (3.52e-3)" EPPK1 EPIPL1 ENSG00000261150 "Epiplakin 1" P58107 8 143857324-143878467 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 15.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 62.9;Basal keratinocytes: 84.7;Suprabasal keratinocytes: 142.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 27.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA066808, HPA067357, HPA069333" Approved Enhanced "Intermediate filaments" NA NA 1200000 "Cluster 13: Skin - Cornification" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Intermediate filaments" "HPA066808: AB_2685726, HPA067357: AB_2685826, HPA069333: AB_2686123" "unprognostic (1.42e-1)" "unprognostic (9.30e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (5.52e-5)" "unprognostic (2.85e-2)" "unprognostic (5.86e-3)" "unprognostic (4.90e-2)" "unprognostic (8.73e-2)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.35e-1)" "unprognostic (1.97e-3)" "unprognostic (5.94e-3)" "unprognostic (4.35e-1)" "unprognostic (3.68e-3)" "unprognostic (5.08e-3)" EPS8L1 "DRC3, FLJ20258, MGC23164, MGC4642" ENSG00000131037 "EPS8 like 1" Q8TE68 19 55072020-55087923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 120.8;skin 1: 57.8" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 504.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041851, HPA043545" Uncertain Supported Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 15: Kidney cancer - Membrane components" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 3 Cytosol "HPA041851: AB_2677706, HPA043545: AB_2678544" "unprognostic (1.91e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (4.44e-4)" "unprognostic (7.18e-2)" "unprognostic (9.33e-2)" "unprognostic (2.54e-2)" "unprognostic (4.61e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.43e-2)" "unprognostic (5.84e-3)" "unprognostic (2.65e-2)" "unprognostic (3.85e-3)" "unprognostic (5.04e-3)" "unprognostic (3.02e-1)" "unprognostic (5.41e-3)" "unprognostic (2.63e-1)" EREG ER ENSG00000124882 Epiregulin O14944 4 74365145-74388749 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 127.2" "Cell type enriched" "Detected in many" 4 "monocytes: 3221.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 126.8" "Adipose visceral - Neutrophils, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047186, HPA054373" Uncertain Vesicles "Secreted to blood" "Growth factor" NA NA 46000 "Cluster 6: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 5 Vesicles "HPA047186: , HPA054373: " "unprognostic (1.26e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (4.56e-3)" "unprognostic (3.94e-2)" "unprognostic (2.24e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (6.57e-5)" "unprognostic (2.94e-1)" "unprognostic (1.70e-6)" "unprognostic (2.42e-2)" "unprognostic (1.13e-2)" "unprognostic (6.59e-3)" "unprognostic (3.16e-3)" ESYT3 "CHR3SYT, FAM62C" ENSG00000158220 "Extended synaptotagmin 3" A0FGR9 3 138434586-138481686 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.2;skin 1: 7.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 26.0;Alveolar cells type 2: 30.8;Cone photoreceptor cells: 8.5;Excitatory neurons: 9.1;Inhibitory neurons: 9.3;Oocytes: 14.0;Rod photoreceptor cells: 7.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Region enhanced" "Detected in many" "hypothalamus: 7.3" "Low region specificity" "Detected in all" HPA039200 Approved NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 29: Non-specific - Unknown function" "Cluster 72: Alveolar cells - Lung function" 2 "HPA039200: AB_10805356" "unprognostic (4.48e-2)" "unprognostic (3.07e-2)" "unprognostic (1.21e-2)" "unprognostic (1.38e-4)" "unprognostic (2.23e-1)" "unprognostic (8.22e-2)" "unprognostic (3.55e-3)" "prognostic favorable (8.30e-4)" "unprognostic (3.38e-1)" "unprognostic (5.57e-2)" "unprognostic (6.19e-3)" "unprognostic (4.88e-3)" "unprognostic (3.16e-5)" "unprognostic (3.46e-1)" "unprognostic (1.12e-1)" "unprognostic (2.13e-1)" "unprognostic (6.43e-2)" FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 68.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 161.4;granulocytes: 63.9;Langerhans cells: 81.4;monocytes: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 546.1;eosinophil: 163.7;intermediate monocyte: 160.5;non-classical monocyte: 249.3" "Group enriched" "Detected in all" 9 "granulocytes: 546.1;monocytes: 249.3" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 25: Non-specific - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 57: Platelets - Hemostasis" 41 "Nucleoplasm, Vesicles" Cytosol "CAB034110: AB_1562838, HPA069240: AB_2686103" "unprognostic (6.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "unprognostic (4.90e-3)" "unprognostic (5.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (9.64e-3)" "unprognostic (1.17e-2)" "unprognostic (6.42e-3)" "unprognostic (4.21e-3)" FAM25A bA96C23.5 ENSG00000188100 "Family with sequence similarity 25 member A" B3EWG3 10 87020294-87024730 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 139.3;esophagus: 505.0;salivary gland: 135.8;skin 1: 169.4;vagina: 187.2" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 123.0" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 53.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 12.0;head and neck cancer: 9.1" "Skin - Keratinocyte (granular)" HPA044808 Uncertain NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA044808: AB_2679096" "unprognostic (9.94e-2)" "unprognostic (2.57e-1)" "unprognostic (7.62e-2)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (1.05e-5)" "unprognostic (1.21e-1)" FAM83F ENSG00000133477 "Family with sequence similarity 83 member F" Q8NEG4 22 39994954-40043534 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 19.7;testis: 39.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 45.2;Late spermatids: 64.9;Proximal enterocytes: 36.1;Suprabasal keratinocytes: 37.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA051207, HPA064657" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 21: Testis - Unknown function" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 1 Mitochondria Nucleoplasm "HPA051207: AB_2681388, HPA064657: AB_2685313" "unprognostic (2.78e-2)" "unprognostic (3.91e-2)" "prognostic favorable (1.73e-4)" "unprognostic (5.36e-2)" "unprognostic (1.48e-5)" "unprognostic (1.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (4.79e-1)" "unprognostic (2.48e-1)" "prognostic favorable (9.40e-4)" "unprognostic (3.25e-1)" "unprognostic (1.10e-7)" "unprognostic (2.93e-1)" "unprognostic (2.37e-1)" "unprognostic (2.98e-2)" "unprognostic (8.32e-2)" FAM83G "FLJ41564, PAWS1" ENSG00000188522 "Family with sequence similarity 83 member G" A6ND36 17 18968789-19004764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 49.8;skin 1: 65.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 81.9;Basal squamous epithelial cells: 40.8;Distal enterocytes: 33.6;Squamous epithelial cells: 55.6;Suprabasal keratinocytes: 92.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA023369, HPA023940" Enhanced Supported Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 1 Cytosol "HPA023369: AB_1848415, HPA023940: AB_1848416" "unprognostic (2.12e-2)" "unprognostic (5.90e-2)" "unprognostic (1.17e-1)" "unprognostic (9.48e-2)" "unprognostic (1.42e-3)" "unprognostic (2.04e-2)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.07e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-2)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (5.65e-2)" "prognostic favorable (7.58e-6)" "unprognostic (9.68e-2)" "unprognostic (5.13e-2)" "unprognostic (3.74e-2)" FBRS "FBS, FBS1, FLJ11618" ENSG00000156860 Fibrosin Q9HAH7 16 30658431-30670810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 126.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044117 Approved Approved Nucleoplasm NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 80: Non-specific - Transcription" 1 Nucleoplasm "HPA044117: AB_10794394" "unprognostic (1.87e-1)" "unprognostic (8.48e-3)" "unprognostic (2.41e-2)" "unprognostic (9.52e-3)" "unprognostic (1.03e-1)" "unprognostic (4.80e-2)" "unprognostic (2.07e-3)" "unprognostic (7.01e-3)" "unprognostic (6.32e-2)" "unprognostic (7.65e-2)" "unprognostic (4.57e-3)" "unprognostic (1.01e-1)" "unprognostic (1.25e-2)" "unprognostic (2.13e-1)" "unprognostic (4.16e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" FBXO45 Fbx45 ENSG00000174013 "F-box protein 45" P0C2W1 3 196568611-196589059 "Predicted intracellular proteins" "Neurogenesis, Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040730 Uncertain Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 72: Testis & Skeletal muscle - Protein ubiquitination" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 33: Non-specific - DNA binding" Cytosol "HPA040730: AB_10959311" "unprognostic (7.17e-3)" "unprognostic (1.14e-1)" "unprognostic (8.37e-2)" "unprognostic (1.01e-2)" "unprognostic (8.14e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.61e-5)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.13e-2)" "unprognostic (9.48e-3)" "unprognostic (1.20e-3)" "prognostic unfavorable (1.16e-5)" "prognostic unfavorable (4.93e-5)" "unprognostic (5.18e-2)" "unprognostic (1.66e-1)" "unprognostic (6.93e-2)" "unprognostic (1.65e-1)" FCHO1 KIAA0290 ENSG00000130475 "FCH and mu domain containing endocytic adaptor 1" O14526 19 17747718-17788568 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Endocytosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.8;lymphoid tissue: 15.6;skin 1: 21.0" "Cell type enhanced" "Detected in many" "dendritic cells: 19.2;Langerhans cells: 17.5;Mesothelial cells: 17.0;Oligodendrocytes: 43.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 23.4;lymphoma: 29.2;Myeloma: 22.3" "Adipose subcutaneous - Macrophages, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041653, HPA062981" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 57: Platelets - Hemostasis" 3 Nucleoplasm Cytosol "HPA041653: AB_10795641, HPA062981: AB_2684915" "unprognostic (3.02e-1)" "unprognostic (9.52e-2)" "unprognostic (1.80e-1)" "unprognostic (4.54e-3)" "unprognostic (3.62e-2)" "unprognostic (5.63e-2)" "unprognostic (3.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.84e-1)" "unprognostic (2.16e-1)" "unprognostic (6.93e-2)" "unprognostic (5.48e-3)" "unprognostic (1.72e-9)" "unprognostic (3.76e-3)" "unprognostic (1.18e-1)" "unprognostic (2.21e-1)" "unprognostic (9.77e-3)" FGF22 ENSG00000070388 "Fibroblast growth factor 22" Q9HCT0 19 639879-644373 "Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.6;skin 1: 13.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.5;Horizontal cells: 13.2;Ovarian stromal cells: 9.0;Rod photoreceptor cells: 6.5;Syncytiotrophoblasts: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in other tissues" "Growth factor" NA NA "Cluster 80: Non-specific - Endocytosis" "Cluster 37: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (2.84e-3)" "unprognostic (1.04e-2)" "unprognostic (1.17e-1)" "unprognostic (5.25e-4)" "unprognostic (1.16e-1)" "unprognostic (3.66e-3)" "unprognostic (2.85e-1)" "unprognostic (1.27e-2)" "unprognostic (1.10e-4)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (3.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.31e-1)" "unprognostic (8.36e-2)" FLG ENSG00000143631 Filaggrin P20930 1 152302165-152325239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "skin 1: 446.3" "Group enriched" "Detected in some" 7 "Basal keratinocytes: 7.0;Suprabasal keratinocytes: 26.6" "Cancer enriched" "Detected in some" 7 "melanoma: 11.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Brain cancer: 17.0;Kidney cancer: 20.6;ovarian cancer: 31.0;Uterine cancer: 37.8" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "CAB002210, HPA027505, HPA030188, HPA030189" Enhanced Enhanced "Cytoplasmic bodies" NA NA 3800000 "Cluster 13: Skin - Cornification" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" 1 "Cytoplasmic bodies" "CAB002210: AB_563731, HPA027505: AB_10600107, HPA030188: AB_10601749, HPA030189: AB_10601999" "unprognostic (3.37e-2)" "unprognostic (3.76e-1)" "unprognostic (8.83e-2)" "unprognostic (2.96e-3)" "unprognostic (9.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-1)" "unprognostic (4.03e-2)" "unprognostic (1.12e-1)" "unprognostic (9.98e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-1)" "unprognostic (2.35e-2)" "unprognostic (1.45e-1)" "unprognostic (4.28e-2)" "unprognostic (4.15e-2)" "unprognostic (7.41e-3)" FLG2 IFPS ENSG00000143520 "Filaggrin 2" Q5D862 1 152348735-152360006 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 471.1" "Cell type enriched" "Detected in some" 8 "Suprabasal keratinocytes: 13.8" "Cancer enriched" "Detected in some" 8 "melanoma: 7.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA028699 Approved NA NA 21000000 "Cluster 13: Skin - Cornification" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA028699: AB_10601905" "unprognostic (2.58e-1)" "unprognostic (2.33e-1)" "unprognostic (3.08e-1)" "unprognostic (6.85e-2)" "unprognostic (6.59e-3)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (1.09e-1)" "unprognostic (2.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.96e-1)" GAN "GAN1, GIG, KLHL16" ENSG00000261609 Gigaxonin Q9H2C0 16 81314944-81390809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 24.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 93.6;Suprabasal keratinocytes: 116.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011825, HPA049473" Approved Supported Microtubules NA NA "Cluster 13: Skin - Cornification" "Cluster 39: Astrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 12: Squamous epithelial cells - Keratinization" 5 Microtubules "CAB011825: AB_732515, HPA049473: AB_2680782" "unprognostic (1.78e-1)" "unprognostic (1.55e-1)" "unprognostic (8.23e-2)" "unprognostic (2.51e-2)" "unprognostic (8.37e-2)" "unprognostic (1.43e-1)" "unprognostic (2.42e-4)" "unprognostic (1.90e-1)" "unprognostic (3.86e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-3)" "unprognostic (5.91e-3)" "unprognostic (3.12e-3)" "unprognostic (5.93e-2)" "unprognostic (9.98e-2)" "unprognostic (1.46e-2)" "unprognostic (5.86e-2)" GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 191.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 129.0;Fibroblasts: 89.7;Oligodendrocytes: 152.0;Schwann cells: 258.9" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.3" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.3" "Cancer enhanced" "Detected in many" "skin cancer: 129.9" "Breast - Fibroblasts, Colon - Enteric glia cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 65: Cerebellum - Nervous system development" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 3 "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" GDF7 BMP12 ENSG00000143869 "Growth differentiation factor 7" Q7Z4P5 2 20667144-20679243 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 9.5;seminal vesicle: 21.7" "Cell type enriched" "Detected in some" 14 "Endometrial stromal cells: 121.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.4" "Adipose subcutaneous - Smooth muscle cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA069106 Approved Vesicles "Secreted in other tissues" Cytokine NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 9: Endometrial stromal cells - Transcription" Vesicles "HPA069106: " "unprognostic (1.35e-1)" "unprognostic (9.93e-3)" "unprognostic (5.10e-1)" "unprognostic (2.44e-3)" "unprognostic (1.35e-1)" "unprognostic (2.06e-3)" "unprognostic (8.63e-3)" "unprognostic (6.31e-3)" "unprognostic (8.00e-3)" "unprognostic (3.85e-1)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.28e-3)" "unprognostic (8.02e-3)" "unprognostic (2.05e-1)" "unprognostic (3.44e-2)" "unprognostic (1.89e-3)" GPRIN2 "KIAA0514, MGC15171" ENSG00000204175 "G protein regulated inducer of neurite outgrowth 2" O60269 10 46541736-46556658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.2;skin 1: 16.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.7;Distal enterocytes: 17.6;Intestinal goblet cells: 47.8;Late spermatids: 20.3;Proximal enterocytes: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 6.0;prostate cancer: 8.1" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA038129, HPA070760" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 16: Intestinal goblet cells - Mucin production" 3 "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA038129: AB_2675846, HPA070760: " "unprognostic (1.00e-2)" "unprognostic (1.91e-1)" "unprognostic (1.77e-2)" "prognostic unfavorable (8.60e-8)" "unprognostic (5.77e-2)" "prognostic favorable (3.47e-4)" "unprognostic (2.23e-1)" "unprognostic (2.67e-2)" "unprognostic (2.54e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "unprognostic (1.98e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.67e-3)" GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 57.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 3.9;Hofbauer cells: 4.4;Kupffer cells: 5.0;Macrophages: 3.4;Mesothelial cells: 3.6;Serous glandular cells: 2.3;Suprabasal keratinocytes: 2.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 7 "granulocytes: 1.0;T-cells: 2.6" "Cancer enhanced" "Detected in some" "breast cancer: 3.9;colorectal cancer: 4.3" "Pancreas - Macrophages, Skin - Keratinocyte (granular), Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 44000 "Cluster 82: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 58: Macrophages - Innate immune response" 2 "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: AB_1850378, HPA064826: AB_2685361" "unprognostic (1.32e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" "unprognostic (2.90e-2)" "unprognostic (1.06e-2)" "unprognostic (9.86e-2)" "unprognostic (7.45e-2)" "unprognostic (3.63e-2)" "unprognostic (3.79e-2)" GSX2 Gsh2 ENSG00000180613 "GS homeobox 2" Q9BZM3 4 54099523-54102498 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Dystonia, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 15 "glioma: 2.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.2;Kidney cancer: 1.1" "Skin - Keratinocyte (granular)" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "Not detected" "Not detected" NA NA "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 52: Non-specific - Cell proliferation" "unprognostic (4.48e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (1.89e-1)" GUCA2B ENSG00000044012 "Guanylate cyclase activator 2B" Q16661 1 42153410-42155820 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 139.3" "Cell type enriched" "Detected in some" 12 "Paneth cells: 24388.4" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "colorectal cancer: 16.5" "Colon - Colon enterocytes, Skin - Keratinocyte (granular), Stomach - Parietal cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Secreted to blood" "No annotated function" NA NA 77700 1200000 "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 40: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" 2 "unprognostic (2.59e-2)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (6.22e-2)" "unprognostic (1.86e-1)" HAL HIS ENSG00000084110 "Histidine ammonia-lyase" P42357 12 95972662-95996365 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "liver: 193.3;skin 1: 59.5" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 15.9;Hepatocytes: 97.9;Kupffer cells: 14.6;monocytes: 28.6" "Cancer enriched" "Detected in some" 11 "liver cancer: 23.7" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 4 "basophil: 57.0;neutrophil: 73.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 73.6" "Group enriched" "Detected in some" 4 "Leukemia: 6.6;liver cancer: 3.0" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Stomach - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038547, HPA038548" Enhanced Approved Cytosol NA NA 280000 "Cluster 35: Neutrophils - Protein binding" "Cluster 83: Liver - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 62: Hepatocytes - Metabolism" Cytosol "HPA038547: AB_10669541, HPA038548: AB_10673175" "unprognostic (3.39e-1)" "unprognostic (4.46e-2)" "unprognostic (1.53e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (5.05e-2)" "unprognostic (2.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-3)" "unprognostic (1.89e-2)" "unprognostic (3.74e-1)" "unprognostic (4.03e-2)" "unprognostic (2.87e-2)" HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 597.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 313.8;Hofbauer cells: 507.7;Kupffer cells: 652.8;Macrophages: 508.8;Syncytiotrophoblasts: 642.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.9;intermediate monocyte: 239.0;non-classical monocyte: 331.0" "Lineage enriched" "Detected in all" 7 "monocytes: 331.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Prostate - Macrophages, Skin - Keratinocyte (granular), Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 40: Monocytes - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" 25 "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" HOPX "HOP, LAGY, NECC1, OB1, SMAP31" ENSG00000171476 "HOP homeobox" Q9BPY8 4 56647988-56681899 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 696.6;skin 1: 1394.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 3293.5;Alveolar cells type 2: 2044.6;NK-cells: 710.1;Suprabasal keratinocytes: 1278.7" "Cancer enhanced" "Detected in many" "glioma: 43.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 519.4;NK-cell: 783.5" "Group enriched" "Detected in all" 15 "NK-cells: 783.5;T-cells: 519.4" "Cancer enhanced" "Detected in many" "lymphoma: 25.4" "Colon - Smooth muscle cells, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018632, HPA030180" Enhanced Approved "Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 2 "Nuclear bodies" Cytosol "CAB018632: AB_2120833, HPA030180: AB_10603770" "unprognostic (2.32e-1)" "unprognostic (1.81e-2)" "unprognostic (8.03e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (1.78e-2)" "unprognostic (2.88e-1)" "unprognostic (7.79e-2)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-5)" "unprognostic (3.40e-2)" "unprognostic (1.51e-1)" "unprognostic (7.10e-2)" "unprognostic (5.33e-2)" HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 229.1;urinary bladder: 363.3" "Cell type enhanced" "Detected in many" "Club cells: 296.3;Distal enterocytes: 340.0;Extravillous trophoblasts: 883.5;granulocytes: 945.1;Hepatocytes: 277.8;Proximal enterocytes: 470.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Region enhanced" "Detected in many" "choroid plexus: 17.4" "Group enriched" "Detected in many" 5 "basophil: 123.8;T-reg: 45.1" "Group enriched" "Detected in many" 73 "granulocytes: 123.8;T-cells: 45.1" "Cancer enhanced" "Detected in many" "testis cancer: 111.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 20000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 30: Granulocytes - Unknown function" Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favorable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" HSPB8 "CMT2L, E2IG1, H11, HSP22" ENSG00000152137 "Heat shock protein family B (small) member 8" Q9UJY1 12 119171555-119224855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" Chaperone "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 865.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 523.7;Skeletal myocytes: 299.6;Syncytiotrophoblasts: 1665.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Smooth muscle cells, Pancreas - Ductal cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015876 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 15 Cytosol Nucleoplasm "HPA015876: AB_1850458" "unprognostic (1.52e-2)" "unprognostic (6.97e-2)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.47e-1)" "unprognostic (4.03e-2)" "unprognostic (7.91e-2)" "unprognostic (6.48e-3)" "unprognostic (1.11e-1)" "unprognostic (1.30e-1)" "unprognostic (2.05e-3)" "unprognostic (2.05e-1)" "unprognostic (6.36e-2)" "unprognostic (2.17e-2)" IDE ENSG00000119912 "Insulin degrading enzyme" P14735 10 92451684-92574096 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Allosteric enzyme, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063478 Approved "Secreted in other tissues" Receptor NA NA 310000 "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 3 "HPA063478: AB_2685020" "unprognostic (1.70e-1)" "unprognostic (6.40e-2)" "prognostic favorable (3.69e-4)" "prognostic favorable (3.53e-4)" "unprognostic (2.54e-1)" "unprognostic (1.78e-1)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (7.79e-2)" "unprognostic (6.81e-2)" "unprognostic (9.24e-3)" "unprognostic (6.13e-2)" "unprognostic (3.89e-2)" "unprognostic (3.91e-1)" IFFO2 ENSG00000169991 "Intermediate filament family orphan 2" Q5TF58 1 18904280-18956676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 164.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 126.6;Salivary duct cells: 56.6;Suprabasal keratinocytes: 118.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "basophil: 12.6" "Lineage enriched" "Detected in single" 18 "granulocytes: 12.6" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015987, HPA064603" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Skin - Cornification" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "HPA015987: AB_2121678, HPA064603: AB_2685296" "unprognostic (1.43e-1)" "unprognostic (1.06e-2)" "unprognostic (2.81e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (4.34e-2)" "unprognostic (2.27e-3)" "unprognostic (3.24e-3)" "unprognostic (7.42e-2)" "unprognostic (3.24e-2)" "unprognostic (5.24e-3)" "unprognostic (2.72e-1)" "unprognostic (4.71e-1)" "unprognostic (1.36e-1)" IGSF22 "FLJ37794, IGFN2" ENSG00000179057 "Immunoglobulin superfamily member 22" Q8N9C0 11 18704312-18726230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.0;skin 1: 1.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 21.4;Distal tubular cells: 21.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Rhabdoid: 1.3" "Skin - Keratinocyte (granular)" "CAB026459, HPA037851" Uncertain Approved Mitochondria NA NA "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB026459: , HPA037851: " "unprognostic (4.05e-2)" "unprognostic (3.65e-2)" "unprognostic (2.34e-2)" "unprognostic (1.84e-1)" "unprognostic (1.23e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (8.38e-2)" "unprognostic (8.70e-2)" "unprognostic (4.24e-2)" "unprognostic (1.99e-4)" "unprognostic (9.35e-2)" "unprognostic (3.72e-4)" "unprognostic (2.87e-1)" "unprognostic (2.18e-1)" "unprognostic (3.43e-1)" "unprognostic (7.94e-3)" IL36B "FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882" ENSG00000136696 "Interleukin 36 beta" Q9NZH7 2 113022089-113052867 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 2.1;lymphoid tissue: 3.7;skin 1: 7.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 1.6;Brain cancer: 3.0" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA035664 Uncertain "Secreted to blood" Interleukin NA NA 8560 "Cluster 13: Skin - Cornification" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Late spermatids - Unknown function" "HPA035664: AB_10669672" "unprognostic (8.45e-2)" "unprognostic (1.62e-1)" "unprognostic (3.56e-2)" "unprognostic (1.06e-1)" "unprognostic (3.77e-2)" "unprognostic (2.40e-3)" "unprognostic (2.05e-1)" "unprognostic (7.10e-3)" IL36G "IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1" ENSG00000136688 "Interleukin 36 gamma" Q9NZH8 2 112973203-112985658 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 13.9;lymphoid tissue: 38.3;skin 1: 30.3" "Group enriched" "Detected in some" 5 "Basal respiratory cells: 132.5;Ionocytes: 47.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 36.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Gallbladder cancer: 50.3;head and neck cancer: 17.3" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA068168 Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Interleukin NA NA 37100 11000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA068168: " "unprognostic (1.56e-2)" "unprognostic (2.88e-1)" "unprognostic (7.27e-2)" "unprognostic (3.15e-2)" "unprognostic (4.91e-2)" "unprognostic (1.92e-1)" "unprognostic (3.68e-1)" "unprognostic (3.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (5.79e-2)" "unprognostic (5.58e-2)" "unprognostic (1.06e-1)" IL36RN "FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840" ENSG00000136695 "Interleukin 36 receptor antagonist" Q9UBH0 2 113058638-113065382 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 25.8;lymphoid tissue: 43.8;skin 1: 58.4" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 9.0;Suprabasal keratinocytes: 9.3;Syncytiotrophoblasts: 4.3" "Cancer enriched" "Detected in some" 7 "head and neck cancer: 25.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.6" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Secreted to blood" Interleukin NA NA 107000 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 11 "unprognostic (3.88e-3)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (4.29e-1)" "unprognostic (8.68e-3)" "unprognostic (9.80e-2)" "unprognostic (2.48e-1)" "unprognostic (5.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" "unprognostic (5.37e-2)" "unprognostic (3.85e-3)" "unprognostic (4.23e-3)" IL37 "FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7" ENSG00000125571 "Interleukin 37" Q9NZH6 2 112911165-112918882 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 117.8" "Cell type enriched" "Detected in some" 5 "Ionocytes: 18.0" "Cancer enriched" "Detected in some" 6 "lung cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.5" "Skin - Keratinocyte (granular)" "HPA054371, HPA057950" Uncertain Supported Nucleoplasm,Vesicles "Secreted to blood" Interleukin NA NA 76700 "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 6 Nucleoplasm Vesicles "HPA054371: AB_2682465, HPA057950: AB_2683561" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.71e-5)" "unprognostic (1.11e-1)" "unprognostic (2.58e-2)" "unprognostic (1.09e-2)" "unprognostic (1.28e-2)" "unprognostic (9.54e-2)" "unprognostic (8.26e-3)" "unprognostic (3.95e-2)" "unprognostic (1.66e-1)" "unprognostic (8.92e-2)" "unprognostic (1.35e-2)" KCTD17 FLJ12242 ENSG00000100379 "Potassium channel tetramerization domain containing 17" Q8N5Z5 22 37051739-37063390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Ubl conjugation pathway" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.5" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 49.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018459 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 29 "HPA018459: AB_1852169" "unprognostic (1.09e-2)" "unprognostic (2.33e-1)" "unprognostic (1.09e-1)" "unprognostic (1.61e-2)" "unprognostic (5.38e-2)" "unprognostic (3.09e-3)" "prognostic unfavorable (3.59e-5)" "unprognostic (1.89e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-1)" "prognostic favorable (4.22e-5)" "unprognostic (8.62e-2)" "prognostic unfavorable (5.13e-12)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (2.32e-1)" "unprognostic (6.94e-2)" KCTD4 bA321C24.3 ENSG00000180332 "Potassium channel tetramerization domain containing 4" Q8WVF5 13 45192853-45201045 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "brain: 51.1" "Cell type enhanced" "Detected in some" "Inhibitory neurons: 2.5;Oligodendrocyte precursor cells: 9.4;Oligodendrocytes: 8.9;Schwann cells: 2.1" "Group enriched" "Detected in some" 5 "glioma: 1.2;renal cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.9;Kidney cancer: 8.0" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040734 Uncertain Approved "Centriolar satellite" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 4 "Centriolar satellite" "HPA040734: AB_10963227" "unprognostic (1.36e-1)" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.19e-2)" "unprognostic (1.70e-1)" "unprognostic (4.68e-2)" "unprognostic (1.74e-1)" "unprognostic (1.66e-3)" "unprognostic (1.63e-1)" "unprognostic (1.73e-1)" "unprognostic (2.15e-1)" "unprognostic (2.98e-2)" KIAA0513 ENSG00000135709 KIAA0513 O60268 16 85027782-85094230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 116.7;pituitary gland: 31.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.7;Horizontal cells: 52.2;Inhibitory neurons: 51.1;Late spermatids: 195.7;monocytes: 53.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 25.1;monocytes: 23.5" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012866, HPA014431" Enhanced Approved Cytosol NA NA 67000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Late spermatids - Spermatogenesis" Cytosol "HPA012866: AB_1852321, HPA014431: AB_1852322" "unprognostic (1.98e-2)" "unprognostic (2.47e-2)" "unprognostic (2.35e-1)" "unprognostic (1.69e-2)" "unprognostic (1.49e-2)" "unprognostic (9.37e-3)" "unprognostic (2.90e-2)" "unprognostic (8.56e-2)" "unprognostic (1.38e-1)" "unprognostic (4.85e-2)" "prognostic favorable (1.72e-5)" "unprognostic (7.52e-2)" "unprognostic (1.94e-3)" "unprognostic (7.88e-2)" "unprognostic (4.00e-1)" "unprognostic (2.33e-2)" "unprognostic (2.34e-1)" KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 122.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" KIF13B "GAKIN, KIAA0639" ENSG00000197892 "Kinesin family member 13B" Q9NQT8 8 29067278-29263124 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "parathyroid gland: 156.3" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 345.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025023, HPA049655" Enhanced NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "HPA025023: AB_1852471, HPA049655: AB_2732555" "unprognostic (1.37e-1)" "unprognostic (4.31e-1)" "prognostic favorable (8.92e-4)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "prognostic favorable (6.26e-4)" "unprognostic (1.04e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-2)" "unprognostic (9.69e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (9.76e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" KIF1C "SAX2, SPAX2, SPG58" ENSG00000129250 "Kinesin family member 1C" O43896 17 4997950-5028401 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 269.3;heart muscle: 179.0;skeletal muscle: 541.6;tongue: 374.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 338.1;Distal enterocytes: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024602, HPA045020" Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 "HPA024602: AB_1852480, HPA045020: AB_2679187" "unprognostic (3.89e-2)" "unprognostic (3.73e-2)" "unprognostic (2.70e-2)" "unprognostic (1.24e-2)" "unprognostic (3.74e-1)" "unprognostic (8.97e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "unprognostic (6.69e-2)" "unprognostic (8.31e-2)" "unprognostic (1.45e-1)" "unprognostic (4.90e-3)" "prognostic favorable (2.26e-9)" "unprognostic (1.10e-1)" "unprognostic (2.28e-1)" "unprognostic (1.41e-1)" "unprognostic (7.10e-3)" KLHL18 "FLJ13703, KIAA0795" ENSG00000114648 "Kelch like family member 18" O94889 3 47282917-47346816 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035027, HPA035028" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 25: Bipolar cells - Visual perception" 1 Nucleoplasm "Nuclear bodies" "HPA035027: AB_10602340, HPA035028: AB_10669899" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (3.82e-2)" "unprognostic (2.26e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.22e-1)" "unprognostic (9.01e-2)" "unprognostic (3.05e-1)" "unprognostic (9.60e-2)" "unprognostic (3.23e-3)" "unprognostic (2.88e-3)" "unprognostic (3.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.07e-1)" "unprognostic (4.67e-1)" KLK5 "KLK-L2, SCTE" ENSG00000167754 "Kallikrein related peptidase 5" Q9Y337 19 50943303-50953093 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 196.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 32.6;Breast myoepithelial cells: 30.1;Early spermatids: 67.4;Late spermatids: 203.1;Mucus glandular cells: 114.9" "Group enriched" "Detected in many" 5 "head and neck cancer: 73.1;melanoma: 32.1;ovarian cancer: 112.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 132.4;head and neck cancer: 188.7" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014343, CAB025503, CAB026341, HPA073512" Enhanced "Secreted in other tissues" Enzyme NA NA 2500000 "Cluster 13: Skin - Cornification" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" 2 "CAB025503: , CAB026341: , HPA014343: AB_1852603, HPA073512: " "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.30e-4)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.04e-1)" "unprognostic (3.05e-1)" "unprognostic (1.70e-3)" "unprognostic (2.21e-1)" "unprognostic (2.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.16e-3)" "prognostic unfavorable (3.85e-6)" KLK9 KLK-L3 ENSG00000213022 "Kallikrein related peptidase 9" Q9UKQ9 19 51002508-51009634 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 11.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.1;head and neck cancer: 8.6" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" CAB025049 Enhanced "Secreted in other tissues" Enzyme NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "CAB025049: " "unprognostic (3.22e-2)" KPRP C1orf45 ENSG00000203786 "Keratinocyte proline rich protein" Q5T749 1 152758025-152762056 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 318.6" "Cell type enriched" "Detected in single" 37 "Suprabasal keratinocytes: 17.3" "Group enriched" "Detected in some" 22 "head and neck cancer: 6.9;melanoma: 13.6" "Region enriched" "Detected in single" 6 "basal ganglia: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 35 "thyroid cancer: 19.3" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "HPA031988, HPA031990" Enhanced NA NA 27000000 "Cluster 13: Skin - Cornification" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 59: Suprabasal keratinocytes - Cornification" 80 "HPA031988: AB_10671582, HPA031990: AB_2674102" "unprognostic (1.03e-1)" "unprognostic (2.67e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" KRT23 "CK23, DKFZP434G032, HAIK1, K23, MGC26158" ENSG00000108244 "Keratin 23" Q9C075 17 40922700-40937646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "salivary gland: 143.4;skin 1: 166.8" "Cell type enriched" "Detected in many" 6 "Syncytiotrophoblasts: 4290.5" "Cancer enhanced" "Detected in many" "urothelial cancer: 61.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 11.5;testis cancer: 6.6" "Adipose visceral - Neutrophils, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA012050, HPA016959, CAB017091" Approved Approved "Intermediate filaments,Cytosol" NA NA 590000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "Intermediate filaments" Cytosol "CAB017091: , HPA012050: AB_1852226, HPA016959: AB_1852228" "unprognostic (1.62e-1)" "unprognostic (5.29e-2)" "unprognostic (4.35e-2)" "unprognostic (6.18e-3)" "unprognostic (1.45e-2)" "unprognostic (2.83e-1)" "unprognostic (5.22e-2)" "unprognostic (6.84e-3)" "unprognostic (2.74e-1)" "unprognostic (2.15e-2)" "unprognostic (8.96e-2)" "unprognostic (1.56e-1)" "unprognostic (8.22e-2)" "unprognostic (6.78e-2)" "unprognostic (1.40e-1)" "unprognostic (2.99e-1)" "prognostic unfavorable (8.26e-4)" LCE1A LEP1 ENSG00000186844 "Late cornified envelope 1A" Q5T7P2 1 152827473-152828097 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "skin 1: 261.0" "Cell type enriched" "Detected in single" 21 "Suprabasal keratinocytes: 17.9" "Cancer enriched" "Detected in some" 6 "melanoma: 14.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 59 "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" LCE1B "LEP2, SPRL2A" ENSG00000196734 "Late cornified envelope 1B" Q5T7P3 1 152811971-152813108 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "skin 1: 162.1" "Cell type enriched" "Detected in single" 21 "Suprabasal keratinocytes: 9.7" "Cancer enriched" "Detected in some" 10 "melanoma: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 69 "unprognostic (1.79e-1)" "unprognostic (1.24e-2)" "unprognostic (6.43e-2)" LCE1C LEP3 ENSG00000197084 "Late cornified envelope 1C" Q5T751 1 152804832-152806651 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "skin 1: 577.0" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 10.3;Suprabasal keratinocytes: 36.9" "Cancer enriched" "Detected in some" 6 "melanoma: 17.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 4.3;head and neck cancer: 2.3" "Skin - Keratinocyte (granular)" NA NA "Cluster 82: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 55 "unprognostic (3.35e-2)" "unprognostic (5.95e-2)" "unprognostic (3.46e-2)" "unprognostic (3.35e-2)" LCE1D LEP4 ENSG00000172155 "Late cornified envelope 1D" Q5T752 1 152796721-152798181 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 94 "skin 1: 78.2" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "melanoma: 4.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 82: Skin - Keratinization" "Cluster 61: BICR 18 - Protein kinases" 47 "unprognostic (7.67e-2)" LCE1E LEP5 ENSG00000186226 "Late cornified envelope 1E" Q5T753 1 152786214-152788426 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 39 "skin 1: 59.5" "Cell type enriched" "Detected in single" 14 "Suprabasal keratinocytes: 6.7" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.9" "Skin - Keratinocyte (granular)" NA NA "Cluster 13: Skin - Cornification" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 52 "unprognostic (9.92e-2)" "unprognostic (9.50e-2)" "unprognostic (2.30e-2)" "unprognostic (2.56e-1)" LCE1F LEP6 ENSG00000240386 "Late cornified envelope 1F" Q5T754 1 152775140-152777024 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "skin 1: 159.2" "Cell type enriched" "Detected in single" 27 "Suprabasal keratinocytes: 2.8" "Group enriched" "Detected in some" 13 "head and neck cancer: 5.5;melanoma: 14.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cervical cancer: 1.8;head and neck cancer: 3.5;thyroid cancer: 1.3" "Skin - Keratinocyte (granular)" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 61 "unprognostic (2.21e-1)" "unprognostic (8.43e-2)" LCE2A LEP9 ENSG00000187173 "Late cornified envelope 2A" Q5TA79 1 152698345-152699442 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 114.9" "Group enriched" "Detected in some" 18 "Melanocytes: 3.4;Pancreatic endocrine cells: 5.1" "Cancer enriched" "Detected in some" 5 "melanoma: 10.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 17 "thyroid cancer: 20.7" "Skin - Keratinocyte (granular)" NA NA "Cluster 82: Skin - Keratinization" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 43 "unprognostic (3.45e-2)" "unprognostic (6.77e-2)" LCE2B "LEP10, SPRL1B, XP5" ENSG00000159455 "Late cornified envelope 2B" O14633 1 152686123-152687397 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 696.7" "Cell type enriched" "Detected in single" 139 "Suprabasal keratinocytes: 14.0" "Cancer enriched" "Detected in some" 5 "melanoma: 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "head and neck cancer: 1.5" "Skin - Keratinocyte (granular)" NA NA "Cluster 82: Skin - Keratinization" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Squamous epithelial cells - Keratinization" 55 "unprognostic (3.04e-2)" "unprognostic (1.36e-1)" LCE2C LEP11 ENSG00000187180 "Late cornified envelope 2C" Q5TA81 1 152675279-152676569 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 310.9" "Cell type enriched" "Detected in single" 12 "Suprabasal keratinocytes: 6.9" "Cancer enriched" "Detected in some" 5 "melanoma: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 13: Skin - Cornification" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Squamous epithelial cells - Keratinization" 71 "unprognostic (1.47e-2)" "unprognostic (7.00e-2)" LCE2D "LEP12, SPRL1A" ENSG00000187223 "Late cornified envelope 2D" Q5TA82 1 152663380-152664659 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "skin 1: 147.2" "Cell type enriched" "Detected in single" 9 "Suprabasal keratinocytes: 2.4" "Group enriched" "Detected in some" 42 "head and neck cancer: 1.2;melanoma: 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Skin - Keratinocyte (granular)" NA NA "Cluster 82: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 51 "unprognostic (3.94e-2)" "unprognostic (5.63e-2)" LCE4A "LEP8, SPRL4A" ENSG00000187170 "Late cornified envelope 4A" Q5TA78 1 152708160-152709434 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "skin 1: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 13: Skin - Cornification" "Cluster 64: Connective tissue cells - ECM organization" 63 "unprognostic (1.61e-2)" LCE5A "LEP18, SPRL5A" ENSG00000186207 "Late cornified envelope 5A" Q5TCM9 1 152510803-152512177 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 88.6" "Group enriched" "Detected in some" 4 "Early spermatids: 1.9;Melanocytes: 1.7;Suprabasal keratinocytes: 3.5" "Cancer enhanced" "Detected in single" "melanoma: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" NA NA "Cluster 13: Skin - Cornification" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" 53 "unprognostic (2.51e-1)" "unprognostic (7.27e-3)" "unprognostic (9.27e-2)" "unprognostic (1.89e-1)" LCE6A C1orf44 ENSG00000235942 "Late cornified envelope 6A" A0A183 1 152842856-152843983 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "skin 1: 239.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "melanoma: 5.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA046376 Enhanced NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA046376: AB_10965998" "unprognostic (4.25e-2)" "unprognostic (8.73e-2)" LIPN "bA186O14.3, LIPL4" ENSG00000204020 "Lipase family member N" Q5VXI9 10 88759982-88779626 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" Hydrolase Ichthyosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 26.0" "Cell type enriched" "Detected in some" 8 "monocytes: 186.5" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "classical monocyte: 2.9;eosinophil: 10.3;intermediate monocyte: 7.5;neutrophil: 5.4;non-classical monocyte: 8.5" "Group enriched" "Detected in many" 8 "granulocytes: 10.3;monocytes: 8.5" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in other tissues" Enzyme NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 82: Skin - Keratinization" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.27e-1)" "unprognostic (1.07e-1)" "unprognostic (2.03e-2)" "unprognostic (9.75e-2)" "unprognostic (2.54e-2)" "unprognostic (4.40e-2)" "unprognostic (5.77e-3)" "unprognostic (1.65e-1)" LORICRIN LOR ENSG00000203782 "Loricrin cornified envelope precursor protein" P23490 1 153259687-153262124 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Keratinization "Ichthyosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "skin 1: 1783.9" "Cell type enriched" "Detected in some" 7 "Suprabasal keratinocytes: 90.5" "Cancer enriched" "Detected in some" 11 "melanoma: 45.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lymphoma: 1.9" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "HPA076123, HPA077266" Enhanced NA NA 1800000 "Cluster 82: Skin - Keratinization" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA076123: AB_2732302, HPA077266: AB_2732338" "unprognostic (1.97e-2)" "unprognostic (1.93e-2)" "unprognostic (4.16e-2)" "prognostic favorable (8.53e-4)" "unprognostic (1.65e-1)" "unprognostic (2.69e-1)" "unprognostic (1.61e-1)" "unprognostic (3.41e-1)" "unprognostic (1.47e-1)" "unprognostic (3.03e-1)" "unprognostic (1.02e-2)" LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 49.0" "Group enriched" "Detected in many" 4 "Early spermatids: 43.2;Late spermatids: 97.5;Syncytiotrophoblasts: 25.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 10.5" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 40: Monocytes - Innate immune response" "Cluster 13: Skin - Cornification" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 8 "Nucleoplasm, Cytosol" "HPA042511: AB_10794279, HPA054670: AB_2682567" "unprognostic (4.27e-3)" "prognostic favorable (5.84e-4)" "unprognostic (4.63e-2)" "unprognostic (8.42e-3)" "unprognostic (4.80e-2)" "unprognostic (2.91e-3)" "unprognostic (3.96e-1)" "unprognostic (7.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (1.40e-3)" "unprognostic (1.19e-1)" "unprognostic (1.83e-3)" "unprognostic (8.30e-2)" "unprognostic (2.02e-1)" "unprognostic (7.53e-3)" "unprognostic (4.08e-2)" MAP1LC3A "ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3" ENSG00000101460 "Microtubule associated protein 1 light chain 3 alpha" Q9H492 20 34546854-34560345 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 653.2;Syncytiotrophoblasts: 283.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 85.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 85.9" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007649, CAB037174, HPA042824, HPA052474, HPA052484" Enhanced Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 65: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Late spermatids - Unknown function" 14 Vesicles "CAB037174: AB_1079382, HPA007649: AB_1853943, HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846" "unprognostic (6.10e-3)" "unprognostic (8.03e-2)" "unprognostic (1.02e-1)" "unprognostic (1.99e-2)" "unprognostic (4.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.55e-1)" "unprognostic (1.79e-1)" "unprognostic (4.78e-2)" "unprognostic (1.98e-1)" "prognostic favorable (5.31e-5)" "unprognostic (2.82e-2)" "unprognostic (1.59e-3)" "unprognostic (3.84e-1)" "unprognostic (1.35e-1)" "unprognostic (7.90e-2)" "unprognostic (2.76e-1)" MAP3K9 "MEKK9, MLK1, PRKE1" ENSG00000006432 "Mitogen-activated protein kinase kinase kinase 9" P80192 14 70722526-70809534 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 9.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 48.0;Inhibitory neurons: 55.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000942 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" Transcription NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 8: Neurons - Neuronal signaling" 4 "Nucleoplasm, Nucleoli" "HPA000942: AB_1079360" "unprognostic (1.20e-1)" "unprognostic (3.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.16e-3)" "unprognostic (2.45e-2)" "unprognostic (3.75e-5)" "unprognostic (2.58e-1)" "unprognostic (4.20e-2)" "unprognostic (4.38e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (4.23e-6)" "unprognostic (5.71e-3)" "unprognostic (6.86e-3)" "unprognostic (1.79e-1)" "unprognostic (2.35e-1)" MAPKAPK3 "3pK, MAPKAP3, MK-3, MK3" ENSG00000114738 "MAPK activated protein kinase 3" Q16644 3 50611520-50649291 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 105.2;heart muscle: 248.1;skeletal muscle: 216.2;tongue: 273.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 233.9;Hofbauer cells: 112.4;monocytes: 201.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 142.9;granulocytes: 126.6;monocytes: 343.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 3 Nucleoplasm "HPA058275: AB_2683663" "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favorable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 84.2;Microglial cells: 109.1;Spermatocytes: 70.9;Syncytiotrophoblasts: 87.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.6;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 34: B-cells - Unknown function" "Cluster 3: Non-specific - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 47: Astrocytes - Unknown function" 3 Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" MPZL3 ENSG00000160588 "Myelin protein zero like 3" Q6UWV2 11 118226690-118252365 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.4;skin 1: 29.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 32.6;Glandular and luminal cells: 34.4;Suprabasal keratinocytes: 41.2;T-cells: 44.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 44.4;eosinophil: 99.4;MAIT T-cell: 28.9;neutrophil: 87.8" "Group enriched" "Detected in all" 8 "granulocytes: 99.4;T-cells: 28.9" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029116 Approved "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Golgi apparatus" "HPA029116: AB_10610142" "unprognostic (2.54e-2)" "unprognostic (1.24e-1)" "unprognostic (5.87e-2)" "unprognostic (1.25e-1)" "unprognostic (3.13e-3)" "unprognostic (1.52e-1)" "unprognostic (8.74e-3)" "unprognostic (2.86e-2)" "unprognostic (9.82e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (4.98e-4)" "unprognostic (4.86e-2)" "unprognostic (1.58e-2)" "unprognostic (1.89e-1)" "unprognostic (3.90e-1)" "prognostic favorable (3.64e-4)" "unprognostic (1.20e-1)" MYO7B ENSG00000169994 "Myosin VIIB" Q6PIF6 2 127535683-127637729 "Predicted intracellular proteins" Differentiation "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 76.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 94.5;Enteroendocrine cells: 33.7;Intestinal goblet cells: 59.2;Paneth cells: 51.7;Proximal enterocytes: 138.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7;naive B-cell: 5.9" "Group enriched" "Detected in many" 22 "B-cells: 5.9;dendritic cells: 2.6;monocytes: 5.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.1;Leukemia: 24.4" "Kidney - Proximal tubular cells, Liver - Vascular Endothelial cells, Pancreas - Ductal cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA039131 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA039131: AB_10672771" "unprognostic (4.10e-3)" "unprognostic (3.81e-2)" "unprognostic (3.80e-2)" "unprognostic (2.23e-4)" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (2.07e-1)" "unprognostic (8.51e-2)" "unprognostic (3.76e-1)" "unprognostic (3.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.80e-2)" "unprognostic (8.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" N4BP3 LZTS4 ENSG00000145911 "NEDD4 binding protein 3" O15049 5 178113532-178126081 "Predicted intracellular proteins" "Immunity, Innate immunity, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.2" "Cell type enriched" "Detected in many" 4 "Extravillous trophoblasts: 155.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 1.7;naive B-cell: 1.6;naive CD8 T-cell: 1.2;plasmacytoid DC: 2.1" "Group enriched" "Detected in many" 16 "B-cells: 1.7;dendritic cells: 2.1;T-cells: 1.2" "Cancer enhanced" "Detected in many" "lymphoma: 12.4" "Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030972, HPA030973, HPA061387" Approved Supported Nucleoplasm,Centrosome NA NA "Cluster 34: B-cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" 12 Nucleoplasm Centrosome "HPA030972: AB_2673680, HPA030973: AB_10603574, HPA061387: " "unprognostic (1.84e-1)" "unprognostic (1.70e-2)" "unprognostic (4.96e-3)" "unprognostic (6.64e-3)" "unprognostic (2.06e-1)" "unprognostic (3.18e-3)" "unprognostic (1.88e-6)" "unprognostic (1.45e-1)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (3.28e-3)" "unprognostic (9.55e-2)" "prognostic favorable (2.38e-4)" "unprognostic (2.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" NCCRP1 "FBXO50, LOC342897, NCCRP-1" ENSG00000188505 "NCCRP1, F-box associated domain containing" Q6ZVX7 19 39196964-39201884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 440.7;skin 1: 264.5;vagina: 176.2" "Cell type enriched" "Detected in many" 4 "Suprabasal keratinocytes: 133.5" "Group enriched" "Detected in many" 4 "cervical cancer: 42.8;head and neck cancer: 48.5;melanoma: 28.3;urothelial cancer: 33.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "cervical cancer: 20.9" "Kidney - Intercalated cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular)" "Region enhanced" "Detected in single" "olfactory bulb: 1.6" "Low region specificity" "Detected in many" "HPA052812, HPA077239" Approved Supported Cytosol NA NA 400000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 14: Langerhans cells - Innate immune response" 1 Cytosol "HPA052812: AB_2681960, HPA077239: " "unprognostic (3.56e-3)" "unprognostic (3.69e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.59e-3)" "unprognostic (3.73e-3)" "unprognostic (2.78e-1)" "unprognostic (3.37e-3)" "unprognostic (1.00e-1)" "unprognostic (3.53e-3)" "unprognostic (2.04e-2)" "unprognostic (1.90e-1)" "unprognostic (6.37e-6)" "unprognostic (2.12e-1)" "unprognostic (3.00e-1)" "unprognostic (2.13e-1)" "unprognostic (1.57e-1)" NFE2 NF-E2 ENSG00000123405 "Nuclear factor, erythroid 2" Q16621 12 54292111-54301015 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 111.0;lymphoid tissue: 44.2" "Cell type enriched" "Detected in some" 7 "Erythroid cells: 155.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "basophil: 1493.0;neutrophil: 813.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 1493.0" "Cancer enriched" "Detected in many" 7 "Leukemia: 95.2" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skin - Keratinocyte (granular), Stomach - Neutrophils, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA001914 Enhanced Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 6 "Nucleoplasm, Actin filaments" "HPA001914: AB_1079475" "unprognostic (2.68e-4)" "unprognostic (2.93e-2)" "unprognostic (2.20e-2)" "unprognostic (2.31e-2)" "unprognostic (2.33e-2)" "unprognostic (1.85e-1)" "unprognostic (1.20e-2)" "unprognostic (4.55e-2)" "unprognostic (4.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-3)" "unprognostic (9.90e-6)" "unprognostic (1.81e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-2)" "unprognostic (3.46e-2)" NKPD1 FLJ33600 ENSG00000179846 "NTPase KAP family P-loop domain containing 1" Q17RQ9 19 45149744-45160982 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 15.4" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.2;Basal prostatic cells: 1.5;Horizontal cells: 2.5;Spermatocytes: 2.0;Suprabasal keratinocytes: 3.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA043339 Uncertain NA NA "Cluster 13: Skin - Cornification" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA043339: AB_10962493" "unprognostic (3.98e-2)" "unprognostic (5.94e-2)" "unprognostic (2.14e-1)" "unprognostic (8.30e-4)" "unprognostic (2.23e-1)" "unprognostic (4.60e-2)" "unprognostic (2.41e-3)" "unprognostic (2.01e-2)" "unprognostic (2.60e-1)" "unprognostic (2.35e-2)" "unprognostic (7.73e-4)" "unprognostic (1.30e-1)" "unprognostic (2.77e-5)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (8.90e-2)" "unprognostic (2.13e-1)" NLRP10 "CLR11.1, NALP10, NOD8, PAN5, Pynod" ENSG00000182261 "NLR family pyrin domain containing 10" Q86W26 11 7957537-7965447 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "breast: 1.4;skin 1: 4.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Skin - Keratinocyte (granular)" "Region enhanced" "Detected in some" "olfactory bulb: 2.1" "HPA039498, HPA040101" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Skin - Cornification" "Cluster 9: Non-specific - Receptor signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Nucleoplasm Cytosol "HPA039498: AB_10795679, HPA040101: AB_10795519" "unprognostic (4.06e-1)" "unprognostic (4.34e-1)" "unprognostic (9.78e-3)" "unprognostic (2.87e-2)" NPAS1 "bHLHe11, MOP5, PASD5" ENSG00000130751 "Neuronal PAS domain protein 1" Q99742 19 47019837-47045775 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;skin 1: 7.5" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 42.5;Gastric mucus-secreting cells: 25.4;Inhibitory neurons: 27.1;Oocytes: 86.8" "Cancer enhanced" "Detected in many" "testis cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 13.5" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA043364, HPA072259" Approved Approved Nucleoplasm NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" Nucleoplasm "HPA043364: , HPA072259: AB_2686500" "unprognostic (2.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.32e-4)" "unprognostic (1.38e-1)" "unprognostic (6.24e-2)" "unprognostic (2.46e-2)" "unprognostic (2.76e-3)" "unprognostic (2.21e-2)" "unprognostic (1.09e-1)" "unprognostic (3.75e-1)" "unprognostic (5.91e-2)" "unprognostic (2.64e-1)" "unprognostic (2.14e-8)" "unprognostic (8.82e-2)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (4.20e-2)" PCSK6 "PACE4, SPC4" ENSG00000140479 "Proprotein convertase subtilisin/kexin type 6" P29122 15 101289784-101525202 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.3;liver: 154.8;lymphoid tissue: 79.2" "Group enriched" "Detected in many" 6 "Hepatocytes: 186.9;Oligodendrocytes: 523.0" "Cancer enhanced" "Detected in many" "liver cancer: 8.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Hepatocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004774 Uncertain "Secreted to extracellular matrix" Enzyme NA NA 480000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" 1 "HPA004774: AB_1079583" "prognostic favorable (9.99e-4)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (2.46e-2)" "unprognostic (9.83e-2)" "unprognostic (8.14e-2)" "unprognostic (2.20e-3)" "unprognostic (8.56e-2)" "unprognostic (2.16e-1)" "unprognostic (2.39e-2)" "unprognostic (3.85e-3)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.06e-7)" "unprognostic (2.02e-1)" "unprognostic (1.87e-1)" "unprognostic (1.15e-1)" "unprognostic (1.03e-2)" PHETA1 "FAM109A, FLJ32356, IPIP27A, SES1" ENSG00000198324 "PH domain containing endocytic trafficking adaptor 1" Q8N4B1 12 111360651-111369121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 41.8;Proximal enterocytes: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 1 "unprognostic (2.26e-1)" "unprognostic (6.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.05e-1)" "unprognostic (6.02e-2)" "unprognostic (1.15e-3)" "unprognostic (6.18e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (5.51e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.95e-1)" "unprognostic (1.31e-1)" "unprognostic (4.90e-2)" "unprognostic (2.80e-3)" PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640671-97676434 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 58: Macrophages - Innate immune response" 1 "Plasma membrane" "CAB030649: , HPA076857: AB_2686817" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108959-45133354 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 82.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.1;Distal enterocytes: 160.2;Paneth cells: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" Nucleoplasm "HPA025711: AB_1855320, HPA053665: AB_2732580" "unprognostic (3.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" "unprognostic (4.14e-3)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.96e-1)" "unprognostic (9.53e-2)" "unprognostic (1.34e-3)" "unprognostic (6.21e-2)" "unprognostic (3.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "prognostic favorable (4.28e-4)" "unprognostic (3.34e-3)" PLCXD1 FLJ11323 ENSG00000182378 "Phosphatidylinositol specific phospholipase C X domain containing 1" Q9NUJ7 X 276322-303356 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 33.0;monocytes: 37.9;Syncytiotrophoblasts: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA007721 Approved Approved Cytosol NA Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 29: Monocytes - Innate immune response" Cytosol "HPA007721: AB_1079630" "unprognostic (2.73e-2)" "unprognostic (5.67e-2)" "unprognostic (4.57e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.80e-2)" "prognostic favorable (2.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.92e-2)" "unprognostic (1.72e-2)" "unprognostic (4.80e-2)" "unprognostic (7.25e-2)" "unprognostic (1.11e-3)" "prognostic unfavorable (7.82e-14)" "unprognostic (6.01e-2)" "unprognostic (1.95e-1)" "unprognostic (3.59e-2)" "unprognostic (1.78e-1)" PLEKHM1 KIAA0356 ENSG00000225190 "Pleckstrin homology and RUN domain containing M1" Q9Y4G2 17 45435900-45490758 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 30.8" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.0" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025018, HPA039473" Approved Supported Nucleoli,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" 7 Vesicles Nucleoli "HPA025018: AB_1855465, HPA039473: AB_2676526" "unprognostic (1.52e-1)" "unprognostic (3.13e-2)" "unprognostic (4.29e-2)" "prognostic favorable (1.28e-6)" "unprognostic (8.71e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.20e-2)" "unprognostic (1.88e-1)" "unprognostic (2.93e-2)" "unprognostic (4.02e-1)" "unprognostic (3.93e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 30.1" "Group enriched" "Detected in some" 4 "Bipolar cells: 33.2;Hepatocytes: 35.7;Rod photoreceptor cells: 35.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Keratinocyte (granular)" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 62: Hepatocytes - Metabolism" Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" PPIF "Cyp-D, CypD, hCyP3" ENSG00000108179 "Peptidylprolyl isomerase F" P30405 10 79347469-79355334 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Necrosis" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 411.2;Macrophages: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 75.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 544.5" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077416 Supported Mitochondria NA NA 320000 "Cluster 21: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Monocytes - Innate immune response" 13 Mitochondria "HPA077416: AB_2686840" "unprognostic (2.21e-1)" "unprognostic (5.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.72e-3)" "unprognostic (1.69e-1)" "unprognostic (3.16e-3)" "unprognostic (3.45e-1)" "unprognostic (4.33e-3)" "unprognostic (1.66e-1)" "unprognostic (1.97e-1)" "unprognostic (2.82e-1)" "unprognostic (9.37e-3)" "unprognostic (1.02e-3)" "unprognostic (1.23e-1)" "unprognostic (1.66e-1)" "unprognostic (1.69e-3)" "unprognostic (4.88e-2)" PRSS8 CAP1 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 238.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 303.3;Extravillous trophoblasts: 770.7;Proximal enterocytes: 331.5;Syncytiotrophoblasts: 632.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "cerebellum: 5.0;choroid plexus: 14.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in some" HPA030436 Uncertain "Secreted - unknown location" Enzyme NA NA 4400000 "Cluster 48: Stomach - Proteolysis" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" PSAPL1 ENSG00000178597 "Prosaposin like 1" Q6NUJ1 4 7430285-7434930 "Predicted secreted proteins" "Lipid metabolism, Sphingolipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skin 1: 95.4;stomach 1: 37.6" "Cell type enriched" "Detected in some" 8 "Gastric mucus-secreting cells: 54.2" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.7;melanoma: 2.5;pancreatic cancer: 2.0;stomach cancer: 3.0;urothelial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.3;Esophageal cancer: 2.0" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038013, HPA038482" Approved Enhanced Cytosol "Secreted - unknown location" Other NA NA 31000 "Cluster 13: Skin - Cornification" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 46: Gastric mucus-secreting cells - Digestion" Cytosol "HPA038013: AB_10673652, HPA038482: AB_2676037" "unprognostic (2.64e-2)" "unprognostic (2.40e-1)" "unprognostic (9.33e-2)" "unprognostic (2.40e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-3)" "unprognostic (2.52e-1)" "unprognostic (2.08e-2)" "unprognostic (2.75e-1)" "unprognostic (2.63e-3)" PSCA lncPSCA ENSG00000167653 "Prostate stem cell antigen" O43653 8 142670308-142682725 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 2937.1" "Group enriched" "Detected in many" 5 "Club cells: 1987.4;Gastric mucus-secreting cells: 4643.3" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 785.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 205.3" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "spinal cord: 50.6" "HPA030783, HPA056418" Approved Supported "Plasma membrane" NA NA 18000 "Cluster 48: Stomach - Proteolysis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" "HPA030783: AB_2673611, HPA056418: AB_2683123" "unprognostic (1.21e-3)" "unprognostic (1.76e-3)" "unprognostic (3.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.77e-2)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.81e-3)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (6.82e-2)" "unprognostic (2.38e-3)" "unprognostic (4.93e-2)" "unprognostic (2.68e-1)" "unprognostic (3.07e-1)" "unprognostic (1.06e-3)" PSG7 ENSG00000221878 "Pregnancy specific beta-1-glycoprotein 7" Q13046 19 42924132-42937207 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "placenta: 4.0;skin 1: 1.2" "Cell type enriched" "Detected in some" 75 "Syncytiotrophoblasts: 128.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 6.5" "Skin - Keratinocyte (granular)" HPA046327 Supported "Secreted in female reproductive system" "No annotated function" NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA046327: AB_2679624" PTGER3 "EP3, lnc003875" ENSG00000050628 "Prostaglandin E receptor 3" P43115 1 70852353-71047816 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 52.2;endometrium 1: 90.7;kidney: 77.9;smooth muscle: 65.5" "Group enriched" "Detected in many" 5 "Distal tubular cells: 156.7;Langerhans cells: 93.2;Mesothelial cells: 50.2" "Group enriched" "Detected in some" 7 "breast cancer: 4.1;renal cancer: 9.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 62 "basophil: 40.2" "Lineage enriched" "Detected in single" 62 "granulocytes: 40.2" "Cancer enriched" "Detected in some" 6 "Bone cancer: 47.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010689 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 51: Thyroid gland - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 28: Dendritic cells - Antigen presentation" "HPA010689: AB_1855883" "unprognostic (1.53e-3)" "unprognostic (3.48e-1)" "unprognostic (1.11e-1)" "unprognostic (3.86e-3)" "unprognostic (1.47e-1)" "unprognostic (3.37e-2)" "unprognostic (4.80e-2)" "unprognostic (2.01e-2)" "unprognostic (1.24e-1)" "unprognostic (4.64e-3)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (8.83e-3)" "unprognostic (1.86e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-4)" RAB11FIP1 "FLJ22524, FLJ22622, Rab11-FIP1, RCP" ENSG00000156675 "RAB11 family interacting protein 1" Q6WKZ4 8 37858618-37899497 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1714.2;Glandular and luminal cells: 908.0;Mucus glandular cells: 792.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 7 "choroid plexus: 85.3" "Immune cell enhanced" "Detected in all" "neutrophil: 102.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 102.1" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017037, HPA023904, HPA024010, HPA025960" Enhanced Enhanced Vesicles No No "Cluster 7: Non-specific - Innate immune response" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 Vesicles "CAB017037: , HPA023904: AB_1855990, HPA024010: AB_1855991, HPA025960: AB_1855992" "unprognostic (1.62e-2)" "unprognostic (3.47e-2)" "unprognostic (3.22e-3)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "prognostic favorable (6.61e-4)" "unprognostic (4.32e-1)" "unprognostic (4.50e-3)" "unprognostic (1.58e-1)" "unprognostic (4.72e-2)" "unprognostic (2.82e-3)" "unprognostic (2.73e-2)" "prognostic favorable (1.14e-6)" "unprognostic (4.94e-2)" "unprognostic (8.41e-2)" "unprognostic (9.99e-2)" "unprognostic (1.50e-1)" RAB11FIP4 "FLJ00131, KIAA1821, MGC11316, RAB11-FIP4" ENSG00000131242 "RAB11 family interacting protein 4" Q86YS3 17 31391675-31538211 "Predicted intracellular proteins" "Host-virus interaction, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;testis: 47.5" "Cell type enriched" "Detected in many" 5 "Late spermatids: 1261.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 78.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 78.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - T-cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063203 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Late spermatids - Spermatogenesis" 1 "HPA063203: AB_2684962" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "prognostic favorable (2.70e-4)" "unprognostic (6.03e-3)" "unprognostic (4.29e-2)" "unprognostic (4.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.20e-1)" "unprognostic (1.16e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.74e-8)" "prognostic favorable (1.22e-4)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (4.13e-3)" RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 275.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 426.3;Inhibitory neurons: 399.2;Microglial cells: 136.0;Oligodendrocyte precursor cells: 284.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.0" "Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Hepatocytes, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 8: Neurons - Neuronal signaling" 6 "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" RHBG SLC42A2 ENSG00000132677 "Rh family B glycoprotein" Q9H310 1 156369211-156385219 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ammonia transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;kidney: 9.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 17.5;Distal tubular cells: 24.6;Granulosa cells: 27.5;Hepatocytes: 10.8;Late spermatids: 15.3;Ovarian stromal cells: 13.8" "Group enriched" "Detected in some" 5 "liver cancer: 14.2;renal cancer: 5.1;urothelial cancer: 4.1" "Region enriched" "Detected in single" 15 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Liver - Hepatocytes, Pancreas - Exocrine glandular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042726, HPA048489" Enhanced Approved Nucleoplasm NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 18: Liver cancer - Metabolism" "Cluster 6: Ovarian stromal cells - Transcription" Nucleoplasm "HPA042726: AB_2678131, HPA048489: AB_2680417" "unprognostic (1.20e-1)" "unprognostic (2.05e-1)" "unprognostic (4.55e-3)" "unprognostic (5.04e-2)" "unprognostic (2.95e-2)" "unprognostic (3.76e-3)" "unprognostic (2.00e-1)" "unprognostic (1.19e-1)" "unprognostic (1.49e-1)" "unprognostic (2.45e-1)" "unprognostic (3.72e-1)" "unprognostic (3.63e-2)" "unprognostic (4.91e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-3)" "prognostic favorable (8.06e-4)" RMND5B "FLJ22318, GID2, GID2B" ENSG00000145916 "Required for meiotic nuclear division 5 homolog B" Q96G75 5 178130996-178150568 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 182.9;Late spermatids: 416.6;Spermatocytes: 112.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047778 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 21: Testis - Unknown function" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Late spermatids - Unknown function" 13 "HPA047778: AB_2680153" "unprognostic (2.08e-1)" "unprognostic (6.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.35e-2)" "unprognostic (4.38e-2)" "unprognostic (9.81e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.48e-1)" "prognostic favorable (7.66e-4)" "unprognostic (1.60e-1)" "prognostic favorable (7.22e-8)" "unprognostic (1.77e-2)" "unprognostic (1.41e-1)" "unprognostic (6.43e-2)" "unprognostic (5.78e-2)" RNASE7 RAE1 ENSG00000165799 "Ribonuclease A family member 7" Q9H1E1 14 21042316-21044234 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 72.5;lymphoid tissue: 23.4;skin 1: 27.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.7;Cholangiocytes: 9.5;Ductal cells: 5.0;Salivary duct cells: 2.4;Suprabasal keratinocytes: 2.6;Syncytiotrophoblasts: 13.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.3;head and neck cancer: 10.2" "Prostate - Prostate basal glandular cells, Skin - Keratinocyte (granular)" "HPA005690, CAB062560, CAB068225" Enhanced "Secreted in other tissues" Enzyme NA NA 280000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "CAB062560: AB_2665595, CAB068225: AB_2665594, HPA005690: AB_1079819" "unprognostic (1.13e-2)" "unprognostic (3.21e-1)" "unprognostic (5.84e-2)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (8.27e-2)" "unprognostic (7.80e-2)" "unprognostic (8.73e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-1)" "unprognostic (2.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.17e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "unprognostic (3.24e-1)" "unprognostic (3.42e-1)" RNF225 ENSG00000269855 "Ring finger protein 225" M0QZC1 19 58395656-58397079 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 2.8;esophagus: 6.4;skin 1: 4.5;vagina: 2.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.1" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "unprognostic (3.07e-1)" "unprognostic (6.94e-2)" "unprognostic (3.68e-3)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "unprognostic (1.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.75e-3)" "unprognostic (1.40e-1)" "unprognostic (3.42e-1)" "unprognostic (9.18e-2)" RNF227 LINC02581 ENSG00000179859 "Ring finger protein 227" A6NIN4 17 7913339-7916289 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 5 "skin 1: 62.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 27.7;Basal squamous epithelial cells: 17.1;Suprabasal keratinocytes: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 17.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 17.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Skin - Cornification" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "unprognostic (8.85e-3)" "prognostic favorable (8.89e-5)" "unprognostic (1.50e-2)" "unprognostic (4.88e-2)" "unprognostic (3.72e-3)" "unprognostic (1.44e-2)" "unprognostic (2.02e-5)" "unprognostic (9.48e-2)" "unprognostic (9.22e-3)" "unprognostic (2.94e-2)" "unprognostic (3.11e-2)" "unprognostic (3.31e-2)" "unprognostic (7.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.18e-1)" "unprognostic (3.30e-2)" "unprognostic (1.80e-2)" RUNDC3A "RAP2IP, RPIP8" ENSG00000108309 "RUN domain containing 3A" Q59EK9 17 44308413-44318670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 298.7;pituitary gland: 95.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 41.5;Enteroendocrine cells: 21.8;Excitatory neurons: 44.6;Horizontal cells: 43.4;Inhibitory neurons: 29.1;Late spermatids: 83.4" "Group enriched" "Detected in many" 5 "glioma: 8.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "lung cancer: 12.2;Neuroblastoma: 48.1" "Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023548, HPA070733" Enhanced Supported Enhanced Vesicles NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" 15 Vesicles "HPA023548: AB_1856069, HPA070733: AB_2732162" "unprognostic (3.66e-2)" "unprognostic (3.77e-2)" "unprognostic (3.50e-3)" "unprognostic (1.58e-3)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (3.87e-3)" "unprognostic (2.29e-1)" "unprognostic (4.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.42e-3)" "unprognostic (1.34e-1)" "unprognostic (8.87e-3)" "unprognostic (1.07e-2)" "unprognostic (5.17e-2)" "unprognostic (9.39e-2)" "unprognostic (1.84e-1)" RXRA "NR2B1, RXR-alpha, RXRalpha" ENSG00000186350 "Retinoid X receptor alpha" P19793 9 134317098-134440585 "Cancer-related genes, FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 102.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 194.8;Kupffer cells: 136.4;monocytes: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.6" "Group enriched" "Detected in many" 5 "granulocytes: 19.6;monocytes: 12.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004565, CAB005352" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Monocytes - Innate immune response" 13 Nucleoplasm "Golgi apparatus" "CAB004565: AB_2184877, CAB005352: AB_2184874" "unprognostic (2.68e-1)" "unprognostic (7.94e-2)" "unprognostic (3.67e-2)" "unprognostic (7.22e-2)" "unprognostic (2.07e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-3)" "prognostic favorable (7.02e-4)" "unprognostic (7.72e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "unprognostic (1.49e-2)" "unprognostic (2.59e-1)" SAPCD1 "C6orf26, NG23" ENSG00000228727 "Suppressor APC domain containing 1" Q5SSQ6 6 31762656-31764850 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071699 Approved "Vesicles,Cell Junctions" NA NA "Cluster 82: Skin - Keratinization" "Cluster 46: Brainstem - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 49: Non-specific - Transcription" Vesicles "Cell Junctions" "HPA071699: AB_2686433" "unprognostic (9.25e-4)" "unprognostic (1.32e-1)" "unprognostic (3.41e-2)" "unprognostic (3.28e-1)" "unprognostic (9.34e-2)" "unprognostic (8.02e-4)" "unprognostic (1.63e-2)" "unprognostic (3.80e-2)" "unprognostic (2.01e-1)" "unprognostic (8.16e-3)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "unprognostic (8.15e-10)" "unprognostic (2.65e-2)" "unprognostic (4.45e-1)" "unprognostic (3.57e-1)" "unprognostic (7.98e-5)" SDCBP2 "SITAC18, ST-2" ENSG00000125775 "Syndecan binding protein 2" Q9H190 20 1309909-1329139 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 137.9;intestine: 133.0;stomach 1: 99.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 217.8;Distal enterocytes: 700.5;Ionocytes: 269.1;Paneth cells: 640.0;Proximal enterocytes: 476.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gastric cancer: 28.9" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005804, HPA064490" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Non-specific - Mixed function" 49 Nucleoplasm "Golgi apparatus, Cytosol" "HPA005804: , HPA064490: AB_2732713" "unprognostic (1.96e-2)" "unprognostic (5.44e-2)" "unprognostic (2.37e-1)" "unprognostic (5.85e-2)" "unprognostic (2.54e-1)" "unprognostic (2.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (1.01e-1)" "unprognostic (3.78e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.17e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.37e-4)" SEMA4D "C9orf164, CD100, coll-4, FLJ39737, SEMAJ" ENSG00000187764 "Semaphorin 4D" Q92854 9 89360787-89498130 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 325.4" "Cell type enhanced" "Detected in many" "monocytes: 78.3;NK-cells: 104.8;Oligodendrocytes: 289.0;T-cells: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 47.6" "Adipose subcutaneous - T-cells, Colon - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015662, HPA023277" Approved NA NA 7500000 "Cluster 21: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" 1 "HPA015662: AB_1856671, HPA023277: AB_1856672" "unprognostic (2.94e-2)" "prognostic favorable (4.17e-4)" "unprognostic (1.12e-2)" "unprognostic (8.22e-2)" "unprognostic (1.41e-1)" "unprognostic (1.76e-3)" "unprognostic (1.27e-1)" "unprognostic (1.58e-1)" "unprognostic (7.79e-2)" "unprognostic (2.74e-1)" "unprognostic (3.18e-3)" "unprognostic (1.50e-2)" "unprognostic (2.29e-3)" "unprognostic (3.05e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-1)" "prognostic favorable (4.06e-5)" SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969504-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 59.0;Hepatocytes: 46.1;Intestinal goblet cells: 35.2;Paneth cells: 37.8;Proximal enterocytes: 45.4;Undifferentiated cells: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" "Developmental protein" NA NA 1300000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.7;lymphoid tissue: 58.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 47.6;dendritic cells: 120.4;Extravillous trophoblasts: 64.0;Rod photoreceptor cells: 51.5;Syncytiotrophoblasts: 173.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 38000000 "Cluster 22: Eosinophils - Transcription" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 1 Vesicles "HPA008210: , HPA042273: AB_10806234" "unprognostic (2.00e-1)" "unprognostic (2.72e-1)" "unprognostic (2.02e-2)" "unprognostic (5.81e-2)" "unprognostic (6.49e-2)" "unprognostic (8.61e-2)" "unprognostic (2.54e-2)" "unprognostic (4.18e-3)" "unprognostic (1.33e-1)" "unprognostic (1.39e-1)" "unprognostic (5.18e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.45e-11)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (6.25e-2)" "unprognostic (2.57e-2)" SERPINB8 "CAP2, PI8" ENSG00000166401 "Serpin family B member 8" P50452 18 63970029-64019779 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 56.9" "Cell type enhanced" "Detected in many" "monocytes: 69.8;Suprabasal keratinocytes: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB034300 Enhanced Approved Nucleoplasm,Cytosol NA NA 920000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 13: Skin - Cornification" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Nucleoplasm Cytosol "CAB034300: AB_2186486" "unprognostic (8.49e-2)" "unprognostic (4.87e-2)" "unprognostic (4.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (7.71e-2)" "unprognostic (4.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.58e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (8.73e-2)" "unprognostic (3.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.90e-1)" SGPL1 SPL ENSG00000166224 "Sphingosine-1-phosphate lyase 1" O95470 10 70815905-70895816 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 138.6" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021125, HPA023086" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 16: Non-specific - Transcription" "Cluster 39: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 45: Non-specific - Mixed function" 29 "Endoplasmic reticulum" "HPA021125: AB_1856803, HPA023086: AB_1856804" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" "unprognostic (2.34e-1)" "unprognostic (7.60e-2)" "unprognostic (2.98e-2)" "unprognostic (2.88e-1)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (2.12e-1)" "unprognostic (9.52e-2)" "unprognostic (3.42e-1)" "unprognostic (2.14e-1)" "unprognostic (9.21e-2)" "unprognostic (4.68e-3)" SLC10A3 "DXS253E, P3" ENSG00000126903 "Solute carrier family 10 member 3" P09131 X 154487306-154490690 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 69.5;Syncytiotrophoblasts: 109.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "basophil: 218.9" "Lineage enriched" "Detected in all" 17 "granulocytes: 218.9" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021656 Approved Approved "Intermediate filaments" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 18: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 57: Platelets - Hemostasis" "Intermediate filaments" "HPA021656: AB_1856955" "unprognostic (1.60e-1)" "prognostic favorable (4.53e-4)" "prognostic unfavorable (4.15e-5)" "unprognostic (8.00e-3)" "prognostic unfavorable (9.97e-4)" "unprognostic (5.47e-2)" "unprognostic (2.28e-3)" "unprognostic (9.76e-2)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.22e-4)" "unprognostic (3.42e-1)" "unprognostic (2.52e-3)" "unprognostic (6.23e-2)" "unprognostic (2.99e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-2)" SLC37A2 "FLJ00171, SPX2" ENSG00000134955 "Solute carrier family 37 member 2" Q8TED4 11 125063302-125090516 "Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 76.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 56.8;Kupffer cells: 38.9;Macrophages: 29.6;Serous glandular cells: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 12.3;intermediate monocyte: 14.1;myeloid DC: 5.5;non-classical monocyte: 19.3" "Group enriched" "Detected in many" 9 "dendritic cells: 5.5;monocytes: 19.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 45.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular), Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014948 Uncertain NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 58: Macrophages - Innate immune response" "HPA014948: AB_2190374" "unprognostic (8.47e-2)" "unprognostic (4.85e-1)" "unprognostic (9.64e-2)" "unprognostic (2.91e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (2.06e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-2)" "unprognostic (3.11e-1)" "unprognostic (6.61e-2)" "unprognostic (1.94e-3)" "unprognostic (1.66e-3)" "unprognostic (7.01e-2)" "unprognostic (3.24e-2)" SLC46A2 "Ly110, TSCOT" ENSG00000119457 "Solute carrier family 46 member 2" Q9BY10 9 112878920-112890876 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 15.9;lung: 10.1;lymphoid tissue: 15.6;skin 1: 23.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 25.2;Ciliated cells: 4.1;Club cells: 4.5;Glandular and luminal cells: 6.4;Hofbauer cells: 5.1;Kupffer cells: 8.4;Late spermatids: 5.2;Macrophages: 4.4" "Cancer enhanced" "Detected in some" "lung cancer: 1.4" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 24.7;intermediate monocyte: 12.1" "Lineage enriched" "Detected in many" 5 "monocytes: 24.7" "Not detected" "Not detected" "Lung - Alveolar cells type 2, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020098 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 13: Skin - Cornification" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 72: Alveolar cells - Lung function" "HPA020098: AB_2670363" "unprognostic (1.26e-1)" "unprognostic (5.15e-3)" "unprognostic (1.10e-2)" "unprognostic (1.53e-3)" "unprognostic (3.57e-3)" "unprognostic (2.10e-2)" "unprognostic (4.56e-1)" "unprognostic (2.18e-1)" "unprognostic (8.10e-2)" "unprognostic (1.50e-3)" "unprognostic (3.50e-1)" "unprognostic (1.38e-1)" "unprognostic (1.77e-2)" "unprognostic (2.37e-1)" "unprognostic (2.71e-2)" "unprognostic (1.83e-1)" "unprognostic (7.82e-2)" SLC49A3 "FLJ22269, LP2561, MFSD7" ENSG00000169026 "Solute carrier family 49 member 3" Q6UXD7 4 681829-689271 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 36.8;Extravillous trophoblasts: 39.0;Hofbauer cells: 34.2;Late spermatids: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043593 Uncertain NA NA "Cluster 21: Testis - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" "HPA043593: AB_10959611" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (8.77e-2)" "unprognostic (4.70e-2)" "unprognostic (9.40e-2)" "unprognostic (1.84e-3)" "unprognostic (2.22e-1)" "unprognostic (1.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.56e-1)" "unprognostic (9.22e-2)" "unprognostic (2.08e-1)" "prognostic favorable (2.66e-5)" "unprognostic (8.35e-2)" "unprognostic (4.92e-2)" "unprognostic (7.48e-2)" "unprognostic (1.11e-1)" SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1010.0;skin 1: 831.0" "Cell type enriched" "Detected in some" 12 "Suprabasal keratinocytes: 2355.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 66.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 1.8;Esophageal cancer: 1.7;head and neck cancer: 2.5" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" Cytokine NA NA 7700000 "Cluster 27: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA050967: AB_2681293" "unprognostic (1.22e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (7.32e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-4)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" SMAP2 SMAP1L ENSG00000084070 "Small ArfGAP2" Q8WU79 1 40344850-40423326 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 211.1" "Cell type enhanced" "Detected in all" "B-cells: 409.4;dendritic cells: 290.9;Kupffer cells: 294.4;Macrophages: 281.4;monocytes: 1153.0;NK-cells: 375.9;Plasma cells: 349.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophil_2, Prostate - Macrophages, Skin - Keratinocyte (granular), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021466, HPA024424" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 10 Cytosol Nucleoplasm "HPA021466: AB_2239737, HPA024424: AB_1857259" "unprognostic (1.65e-1)" "prognostic favorable (6.55e-4)" "unprognostic (7.17e-2)" "unprognostic (1.40e-3)" "unprognostic (4.32e-1)" "prognostic favorable (5.34e-5)" "prognostic unfavorable (2.53e-4)" "unprognostic (9.05e-2)" "unprognostic (2.27e-1)" "unprognostic (2.24e-1)" "unprognostic (4.00e-3)" "unprognostic (2.65e-1)" "unprognostic (1.02e-2)" "unprognostic (1.88e-2)" "unprognostic (5.45e-2)" "unprognostic (6.23e-2)" "unprognostic (1.24e-1)" SMPD1 ASM ENSG00000166311 "Sphingomyelin phosphodiesterase 1" P17405 11 6390440-6394998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Neurodegeneration, Niemann-Pick disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 92.2;Late spermatids: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 2700000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 5: Enterocytes - Absorption" 1 "unprognostic (8.76e-2)" "unprognostic (2.66e-1)" "unprognostic (6.99e-2)" "unprognostic (2.28e-3)" "prognostic unfavorable (7.72e-5)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (4.90e-2)" "unprognostic (8.06e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.47e-4)" "unprognostic (4.35e-2)" "prognostic favorable (4.57e-6)" "unprognostic (4.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" "unprognostic (1.71e-1)" SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.8;lymphoid tissue: 50.7" "Cell type enhanced" "Detected in many" "dendritic cells: 221.5;Gastric mucus-secreting cells: 61.3;Horizontal cells: 71.8;Oocytes: 75.0;Proximal enterocytes: 102.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 139.0" "Lineage enriched" "Detected in many" 7 "dendritic cells: 139.0" "Cancer enhanced" "Detected in many" "Leukemia: 11.1;lymphoma: 12.1;Neuroblastoma: 11.2" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Peritubular cells" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 83.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" SPAG1 "CILD28, CT140, DNAAF13, FLJ32920, HSD-3.8, SP75, TPIS" ENSG00000104450 "Sperm associated antigen 1" Q07617 8 100157906-100259278 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Fertilization Hydrolase "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ciliated cells: 149.2;Early spermatids: 129.7;Spermatocytes: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023748, HPA053682" Enhanced Supported Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 46: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 42: Ciliated cells - Cilium assembly" Cytosol "HPA023748: AB_2671304, HPA053682: AB_2682229" "unprognostic (9.95e-2)" "unprognostic (5.37e-2)" "unprognostic (1.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-1)" "unprognostic (2.57e-1)" "unprognostic (5.86e-2)" "unprognostic (9.19e-2)" "unprognostic (1.53e-1)" "unprognostic (5.62e-2)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.87e-4)" "unprognostic (9.11e-3)" "unprognostic (8.83e-3)" "unprognostic (1.54e-1)" "prognostic favorable (2.62e-4)" SPNS2 SLC63A2 ENSG00000183018 "Sphingolipid transporter 2" Q8IVW8 17 4498881-4539035 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 49.6" "Cell type enhanced" "Detected in many" "Adipocytes: 35.6;Endothelial cells: 40.1;Extravillous trophoblasts: 35.1;Gastric mucus-secreting cells: 31.8;Microglial cells: 35.8;Oligodendrocytes: 91.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Keratinocyte (granular), Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068717 Uncertain NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA068717: AB_2686021" "unprognostic (3.03e-2)" "unprognostic (4.76e-2)" "unprognostic (8.08e-2)" "unprognostic (3.53e-2)" "unprognostic (2.78e-1)" "unprognostic (6.30e-3)" "unprognostic (1.10e-3)" "unprognostic (2.33e-1)" "unprognostic (1.70e-1)" "unprognostic (1.63e-3)" "unprognostic (2.99e-2)" "unprognostic (2.98e-2)" "unprognostic (4.48e-2)" "unprognostic (2.20e-2)" "unprognostic (1.68e-1)" "unprognostic (2.19e-2)" "unprognostic (6.89e-2)" SPRR5 ENSG00000283227 "Small proline rich protein 5" A0A1B0GTR4 1 152947206-152949255 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 21 "skin 1: 111.5" "Cell type enriched" "Detected in some" 4 "Suprabasal keratinocytes: 7.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 2.2" "Skin - Keratinocyte (granular)" NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" SPTLC3 "C20orf38, FLJ11112, hLCB2b, LCB2B, SPTLC2L" ENSG00000172296 "Serine palmitoyltransferase long chain base subunit 3" Q9NUV7 20 13008972-13169103 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 27.8;Early spermatids: 34.4;Glandular and luminal cells: 47.1;Microglial cells: 34.0;Syncytiotrophoblasts: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA044247, HPA048079" Enhanced Approved Microtubules NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Skin - Cornification" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 Microtubules "HPA044247: AB_2678872, HPA048079: AB_2680252" "unprognostic (6.81e-2)" "unprognostic (7.76e-2)" "unprognostic (4.46e-2)" "unprognostic (1.25e-3)" "unprognostic (5.43e-2)" "unprognostic (2.12e-1)" "unprognostic (5.70e-2)" "unprognostic (7.99e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (5.08e-2)" "prognostic favorable (4.51e-7)" "unprognostic (2.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (3.18e-1)" STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042079-172188224 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 75.6" "Cell type enhanced" "Detected in many" "Kupffer cells: 86.9;Macrophages: 64.5;monocytes: 136.2;NK-cells: 155.0;T-cells: 86.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 16000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: AB_2669151" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favorable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" STK40 "MGC4796, SgK495" ENSG00000196182 "Serine/threonine kinase 40" Q8N2I9 1 36339624-36385924 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 115.7;Late spermatids: 228.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 25.3" "Group enriched" "Detected in all" 5 "granulocytes: 25.3;monocytes: 12.0" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008026 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Late spermatids - Spermatogenesis" 2 Cytosol Nucleoplasm "HPA008026: AB_1857603" "unprognostic (3.32e-1)" "unprognostic (3.00e-1)" "unprognostic (6.47e-2)" "unprognostic (4.55e-1)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (2.69e-3)" "unprognostic (6.09e-2)" "unprognostic (2.09e-1)" "unprognostic (5.96e-2)" "prognostic favorable (5.59e-4)" "unprognostic (1.19e-1)" "unprognostic (2.75e-2)" "unprognostic (7.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-2)" STRA8 ENSG00000146857 "Stimulated by retinoic acid 8" Q7Z7C7 7 135231979-135258663 "Predicted intracellular proteins" "Differentiation, DNA replication, Meiosis, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Oocytes: 5.9;Spermatogonia: 10.6" "Cancer enhanced" "Detected in many" "renal cancer: 2.1" "Region enriched" "Detected in many" 8 "choroid plexus: 20.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA078044 Approved Cytosol NA NA "Cluster 36: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 67: Spermatogonia - Spermatogenesis" 7 Cytosol "HPA078044: " "unprognostic (2.84e-1)" "unprognostic (4.86e-2)" "unprognostic (3.89e-2)" "unprognostic (9.67e-4)" "unprognostic (1.21e-1)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (1.26e-3)" "unprognostic (1.25e-1)" "unprognostic (8.55e-3)" "unprognostic (1.45e-1)" "unprognostic (2.69e-1)" TEAD4 "EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1" ENSG00000197905 "TEA domain transcription factor 4" Q15561 12 2959330-3040676 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 122.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 34.3;Cytotrophoblasts: 53.0;Exocrine glandular cells: 29.1;Proximal enterocytes: 38.7" "Cancer enriched" "Detected in all" 5 "testis cancer: 78.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Prostate - Endothelial cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Region enriched" "Detected in single" 5 "cerebellum: 3.1" "Low region specificity" "Detected in all" HPA056896 Uncertain Supported Nucleoplasm NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 12: Non-specific - Vasculature" "Cluster 38: Non-specific - Transcription" "Cluster 24: Cytotrophoblasts - Mitochondria" 30 Nucleoplasm "HPA056896: AB_2683268" "unprognostic (3.68e-1)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.55e-3)" "unprognostic (1.33e-1)" "unprognostic (3.68e-1)" "unprognostic (9.20e-3)" "unprognostic (2.21e-3)" "unprognostic (3.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (9.78e-9)" "unprognostic (5.05e-3)" "unprognostic (8.43e-2)" "unprognostic (2.42e-2)" "unprognostic (1.23e-3)" TEX264 "FLJ13935, ZSIG11" ENSG00000164081 "Testis expressed 264, ER-phagy receptor" Q9Y6I9 3 51662693-51704323 "Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 351.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005002, HPA017739, HPA073223" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 23 "Endoplasmic reticulum" "CAB005002: AB_425976, HPA017739: AB_1857910, HPA073223: " "unprognostic (2.80e-3)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (2.79e-3)" "unprognostic (8.11e-2)" "unprognostic (8.26e-3)" "unprognostic (2.05e-1)" "unprognostic (3.06e-3)" "unprognostic (2.30e-1)" "unprognostic (5.19e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.83e-1)" "prognostic favorable (7.95e-9)" "unprognostic (4.99e-2)" "unprognostic (3.65e-1)" "unprognostic (3.17e-1)" "unprognostic (4.67e-2)" TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 693.4" "Group enriched" "Detected in many" 4 "Mesothelial cells: 114.1;Suprabasal keratinocytes: 396.6" "Group enriched" "Detected in many" 4 "cervical cancer: 30.8;head and neck cancer: 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 41.9" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171, HPA070372" Enhanced Approved "Vesicles,Plasma membrane" NA NA 530000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 24 "Vesicles, Plasma membrane" "CAB015159: AB_2202870, HPA040171: AB_2676869, HPA070372: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" THAP11 "CTG-B43a, CTG-B45d, HRIHFB2206, RONIN" ENSG00000168286 "THAP domain containing 11" Q96EK4 16 67842320-67844195 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041434, HPA042189, HPA072537" Supported Supported Nucleoplasm,Cytosol NA No "Cluster 33: Non-specific - ATP binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 33: Non-specific - DNA binding" 5 Nucleoplasm Cytosol "HPA041434: AB_10960385, HPA042189: AB_10964636, HPA072537: " "unprognostic (1.43e-1)" "unprognostic (2.51e-1)" "unprognostic (2.82e-1)" "unprognostic (1.54e-3)" "unprognostic (1.93e-3)" "unprognostic (1.40e-2)" "unprognostic (1.56e-3)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (2.34e-1)" "unprognostic (1.66e-1)" "unprognostic (9.51e-2)" "unprognostic (2.97e-1)" "unprognostic (2.11e-1)" "unprognostic (2.10e-2)" "unprognostic (4.59e-2)" "unprognostic (5.87e-2)" TIGD5 FLJ14926 ENSG00000179886 "Tigger transposable element derived 5" Q53EQ6 8 143597831-143603224 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 21.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 33: Non-specific - DNA binding" "unprognostic (1.90e-1)" "unprognostic (7.91e-2)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.22e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (2.79e-2)" "unprognostic (1.12e-1)" "unprognostic (6.72e-2)" "unprognostic (2.75e-3)" "unprognostic (3.16e-1)" "prognostic favorable (9.16e-5)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (2.32e-1)" "unprognostic (4.04e-1)" TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 238.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 145.0;Hepatocytes: 181.3;Muller glia cells: 171.4;Prostatic glandular cells: 143.4;Suprabasal keratinocytes: 205.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 38.2" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 109.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Stomach - Parietal cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 60: Prostate cancer - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 2 "Endoplasmic reticulum" Vesicles "HPA030691: AB_10602480, HPA072704: AB_2686551" "unprognostic (1.62e-1)" "unprognostic (5.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (6.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "unprognostic (1.69e-1)" "prognostic favorable (8.49e-8)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.44e-2)" TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 73.4;pancreas: 87.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.1;Alveolar cells type 2: 178.6;Distal enterocytes: 75.1;Proximal enterocytes: 169.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" "Midbody, Cytosol" "HPA015796: AB_1858081" "unprognostic (2.53e-3)" "unprognostic (8.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (8.50e-2)" "unprognostic (8.37e-3)" "prognostic favorable (5.11e-5)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-1)" "unprognostic (5.16e-2)" TMEM86A FLJ90119 ENSG00000151117 "Transmembrane protein 86A" Q8N2M4 11 18693122-18704785 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 17.1" "Cell type enhanced" "Detected in many" "Early spermatids: 15.8;Hofbauer cells: 35.9;Late spermatids: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 11.4" "Breast - Breast glandular cells, Lung - Macrophages, Pancreas - Macrophages, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057119 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" 38 "Nucleoplasm, Golgi apparatus" "HPA057119: AB_2683342" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (8.08e-3)" "unprognostic (1.89e-1)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (4.05e-2)" "unprognostic (2.94e-1)" "unprognostic (3.73e-1)" "unprognostic (1.74e-1)" "unprognostic (8.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.36e-1)" "unprognostic (1.50e-2)" "unprognostic (7.92e-2)" "unprognostic (4.20e-1)" "unprognostic (3.24e-1)" TMPRSS11F "FLJ16046, HATL4" ENSG00000198092 "Transmembrane serine protease 11F" Q6ZWK6 4 68053198-68129869 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 14.7;skin 1: 9.0;vagina: 4.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.7;Cytotrophoblasts: 1.6;Squamous epithelial cells: 7.5;Suprabasal keratinocytes: 8.6" "Group enriched" "Detected in some" 7 "cervical cancer: 1.6;head and neck cancer: 2.1;lung cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1;Leukemia: 1.0;lymphoma: 1.8" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA026911 Uncertain NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA026911: AB_2205589" "unprognostic (9.46e-2)" "unprognostic (5.30e-1)" "unprognostic (7.16e-2)" "unprognostic (8.79e-3)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (1.22e-1)" "unprognostic (5.08e-2)" TMPRSS13 "MSPL, MSPS, TMPRSS11" ENSG00000137747 "Transmembrane serine protease 13" Q9BYE2 11 117900641-117929459 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 15.3;skin 1: 39.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.8;Extravillous trophoblasts: 22.7;Glandular and luminal cells: 11.6;Salivary duct cells: 13.9;Suprabasal keratinocytes: 21.3;Syncytiotrophoblasts: 21.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 15.5" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA079555 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 13: Skin - Cornification" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Nucleoplasm, Plasma membrane" "HPA079555: " "unprognostic (1.08e-3)" "unprognostic (5.18e-2)" "unprognostic (6.59e-2)" "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (5.61e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.03e-1)" "unprognostic (3.16e-6)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (1.08e-1)" "unprognostic (3.44e-1)" TNFAIP8L3 FLJ41287 ENSG00000183578 "TNF alpha induced protein 8 like 3" Q5GJ75 15 51056598-51105276 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 84.1;smooth muscle: 81.6" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 13.8;Lymphatic endothelial cells: 38.6;Smooth muscle cells: 20.4;Spermatocytes: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.3" "Adipose subcutaneous - Smooth muscle cells, Prostate - Fibroblasts, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077484 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 Cytosol Nucleoplasm "HPA077484: AB_2732347" "unprognostic (1.38e-1)" "unprognostic (6.22e-2)" "unprognostic (1.12e-3)" "unprognostic (6.63e-2)" "unprognostic (2.54e-1)" "unprognostic (1.35e-2)" "unprognostic (3.08e-2)" "unprognostic (2.15e-2)" "unprognostic (4.21e-2)" "unprognostic (4.70e-3)" "unprognostic (6.54e-2)" "unprognostic (9.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (3.51e-4)" TNNC1 TNNC ENSG00000114854 "Troponin C1, slow skeletal and cardiac type" P63316 3 52451100-52454041 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 36 "heart muscle: 8453.2;skeletal muscle: 20351.8;tongue: 11901.7" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 986.3;Skeletal myocytes: 2797.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 27.1" "Group enriched" "Detected in many" 6 "cerebellum: 5.0;choroid plexus: 15.5" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 6 "T-cells: 1.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 94.2" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (granular)" "Region enriched" "Detected in all" 4 "cerebral cortex: 87.0" "Group enriched" "Detected in some" 6 "midbrain: 10.1;spinal cord: 9.5" "CAB002450, HPA044848, HPA056897" Enhanced Approved "Nucleoplasm,Actin filaments,Mitochondria" NA NA 990000 "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 5: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" 2 "Nucleoplasm, Actin filaments, Mitochondria" "CAB002450: AB_564152, HPA044848: AB_2679110, HPA056897: AB_2683269" "unprognostic (2.18e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (3.43e-1)" "unprognostic (4.00e-2)" "unprognostic (1.88e-2)" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-1)" "unprognostic (3.92e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (2.15e-2)" "unprognostic (4.95e-2)" "unprognostic (2.31e-1)" "unprognostic (4.15e-2)" "unprognostic (4.86e-1)" TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347992 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 206.3" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 189.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000818, HPA001749" Approved Approved "Plasma membrane,Centriolar satellite,Cytosol" NA NA 44000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Monocytes - Innate immune response" 2 Cytosol "Plasma membrane, Centriolar satellite" "HPA000818: AB_2666101, HPA001749: AB_1080323" "unprognostic (3.75e-1)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.11e-2)" "unprognostic (7.55e-2)" "unprognostic (4.07e-3)" "unprognostic (2.24e-1)" "unprognostic (9.92e-2)" "unprognostic (2.32e-1)" "unprognostic (3.71e-1)" "unprognostic (8.16e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" "unprognostic (7.54e-3)" "unprognostic (3.31e-2)" TOM1L2 ENSG00000175662 "Target of myb1 like 2 membrane trafficking protein" Q6ZVM7 17 17843511-17972422 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 171.2;Oligodendrocytes: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022541, HPA023304" Enhanced Approved "Golgi apparatus,Intermediate filaments" NA NA 73000 "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 47: Astrocytes - Unknown function" 1 "Golgi apparatus, Intermediate filaments" "HPA022541: AB_1858182, HPA023304: AB_1858183" "unprognostic (2.32e-1)" "unprognostic (7.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.57e-2)" "unprognostic (3.25e-2)" "prognostic favorable (1.24e-4)" "unprognostic (2.22e-1)" "unprognostic (1.08e-1)" "unprognostic (6.29e-2)" "prognostic unfavorable (2.58e-4)" "prognostic favorable (1.92e-4)" "unprognostic (3.19e-2)" "prognostic favorable (6.21e-9)" "unprognostic (7.11e-2)" "unprognostic (1.40e-1)" "unprognostic (4.18e-2)" "unprognostic (4.51e-2)" TPRN "C9orf75, DFNB79, FLJ90254" ENSG00000176058 Taperin Q4KMQ1 9 137191617-137204193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.1;pancreas: 88.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 53.0;Distal enterocytes: 163.1;Proximal enterocytes: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 48.0" "HPA020899, HPA076667" Approved Approved "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "Plasma membrane" "HPA020899: AB_1845835, HPA076667: " "unprognostic (5.41e-2)" "prognostic favorable (2.13e-4)" "unprognostic (2.94e-1)" "unprognostic (9.28e-2)" "unprognostic (1.68e-1)" "unprognostic (2.61e-2)" "unprognostic (3.59e-3)" "unprognostic (8.20e-2)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.89e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.16e-9)" "unprognostic (1.96e-3)" "unprognostic (6.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.44e-2)" TREX2 ENSG00000183479 "Three prime repair exonuclease 2" Q9BQ50 X 153444473-153470587 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 19.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 6 "choroid plexus: 11.9" "Group enriched" "Detected in some" 7 "basophil: 2.1;eosinophil: 2.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.6" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" HPA054060 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 23: Choroid plexus - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 "HPA054060: AB_2682362" "unprognostic (2.32e-2)" "unprognostic (2.05e-3)" "unprognostic (1.13e-3)" "unprognostic (7.18e-4)" "unprognostic (6.05e-2)" "unprognostic (1.81e-2)" "unprognostic (8.40e-2)" "unprognostic (2.19e-1)" "unprognostic (2.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (1.52e-1)" "unprognostic (9.34e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-2)" TRIB3 "C20orf97, dJ1103G7.3, TRB3" ENSG00000101255 "Tribbles pseudokinase 3" Q96RU7 20 362835-397559 "Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 78.5" "Cell type enhanced" "Detected in many" "Ductal cells: 45.6;Hepatocytes: 31.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA015272, HPA055442" Approved Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" 54 Nucleoplasm "HPA015272: AB_1858269, HPA055442: AB_2682818" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.25e-3)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.70e-4)" "prognostic unfavorable (6.75e-5)" "unprognostic (1.52e-3)" "unprognostic (1.76e-1)" "unprognostic (1.24e-1)" "unprognostic (7.95e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.07e-13)" "unprognostic (7.62e-2)" "unprognostic (2.79e-2)" "unprognostic (2.31e-1)" "unprognostic (4.05e-3)" TULP1 "LCA15, RP14, TUBL1" ENSG00000112041 "TUB like protein 1" O00294 6 35497874-35512896 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Sensory transduction, Vision" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 172 "retina: 202.7" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 535.2;Rod photoreceptor cells: 346.7" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Brain cancer: 1.0" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Other NA NA "Cluster 76: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 2 "unprognostic (7.98e-2)" "unprognostic (2.33e-2)" "unprognostic (4.38e-2)" "unprognostic (4.60e-5)" "unprognostic (2.28e-2)" "unprognostic (3.12e-3)" "unprognostic (3.30e-1)" "unprognostic (5.49e-3)" "unprognostic (1.85e-1)" "unprognostic (2.66e-2)" "unprognostic (7.42e-2)" "unprognostic (1.66e-6)" "unprognostic (1.72e-1)" "unprognostic (1.30e-1)" "unprognostic (5.42e-2)" "unprognostic (4.11e-2)" TYRO3 "Brt, Dtk, Etk-2, Rek, RSE, Sky, Tif" ENSG00000092445 "TYRO3 protein tyrosine kinase" Q06418 15 41557675-41583589 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.2;ovary: 45.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 41.0;Granulosa cells: 64.3;Leydig cells: 44.2;Oligodendrocytes: 43.6;Ovarian stromal cells: 54.4;Peritubular cells: 45.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Enteric glia cells, Kidney - Podocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071245 Approved NA NA 17000000 "Cluster 66: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" 13 "HPA071245: AB_2686371" "unprognostic (1.26e-1)" "unprognostic (6.34e-2)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.77e-2)" "unprognostic (1.56e-3)" "unprognostic (5.41e-2)" "unprognostic (3.72e-1)" "unprognostic (3.21e-1)" "unprognostic (2.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.92e-10)" "unprognostic (7.59e-2)" "unprognostic (5.22e-1)" "unprognostic (4.04e-3)" "unprognostic (1.84e-2)" UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655722-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.6;lymphoid tissue: 15.2;placenta: 13.3" "Cell type enhanced" "Detected in many" "dendritic cells: 119.3;Extravillous trophoblasts: 60.4;Inhibitory neurons: 158.8;Langerhans cells: 61.3;monocytes: 106.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038605, HPA038606, HPA038607" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 23000 "Cluster 25: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 65: Neurons - Synaptic function" 25 Cytosol "Nucleoplasm, Nuclear bodies" "HPA038605: AB_10669648, HPA038606: , HPA038607: AB_2676112" "unprognostic (4.94e-2)" "unprognostic (6.03e-3)" "unprognostic (1.34e-1)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (1.49e-1)" "unprognostic (9.09e-2)" "unprognostic (4.67e-3)" "unprognostic (1.21e-1)" "unprognostic (1.95e-1)" "unprognostic (1.46e-3)" "unprognostic (6.20e-2)" "unprognostic (9.02e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (2.72e-3)" "unprognostic (1.53e-1)" UBL7 "BMSC-UbP, MGC14421" ENSG00000138629 "Ubiquitin like 7" Q96S82 15 74445977-74461182 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 175.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040423, HPA041897" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 15: Non-specific - Mixed function" 2 Nucleoplasm Cytosol "HPA040423: AB_10673442, HPA041897: AB_2677732" "unprognostic (4.21e-2)" "prognostic favorable (6.37e-5)" "unprognostic (2.93e-3)" "unprognostic (5.56e-2)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "unprognostic (3.43e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (6.71e-2)" "unprognostic (5.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.47e-3)" "unprognostic (8.94e-3)" "unprognostic (7.05e-2)" "unprognostic (2.75e-1)" "unprognostic (3.43e-2)" USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381711 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 162.4" "Group enriched" "Detected in many" 6 "Early spermatids: 335.3;Late spermatids: 1103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Myeloma: 14.9" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 63: Late spermatids - Spermatogenesis" 78 Cytosol "Plasma membrane" "HPA006777: AB_1080507, HPA007222: AB_1080505" "unprognostic (6.83e-2)" "unprognostic (2.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-3)" "unprognostic (8.02e-3)" "unprognostic (7.33e-2)" "prognostic favorable (3.09e-11)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (2.66e-2)" VAT1 "FLJ20230, VATI" ENSG00000108828 "Vesicle amine transport 1" Q99536 17 43014607-43025123 "Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Melanocytes: 144.3" "Cancer enhanced" "Detected in all" "melanoma: 295.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 104.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 104.5" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045170 Uncertain NA NA 2700000 "Cluster 32: Basophils - Transcription" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" 1 "HPA045170: AB_10964166" "unprognostic (2.22e-2)" "unprognostic (4.41e-3)" "unprognostic (6.86e-3)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (9.67e-2)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.16e-2)" "unprognostic (5.56e-2)" "unprognostic (1.86e-2)" "unprognostic (1.17e-3)" "unprognostic (2.38e-1)" "prognostic favorable (5.89e-4)" "unprognostic (1.71e-2)" "unprognostic (3.66e-2)" "unprognostic (1.07e-1)" "unprognostic (3.36e-2)" VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 423.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 262.9;Enteroendocrine cells: 134.4;Intestinal goblet cells: 144.6;Paneth cells: 211.1;Proximal enterocytes: 583.3;Undifferentiated cells: 133.2" "Group enriched" "Detected in many" 4 "colorectal cancer: 56.4;stomach cancer: 23.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in many" 5 "Bile duct cancer: 128.5;colorectal cancer: 290.7;Gastric cancer: 138.2;liver cancer: 154.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA 6800 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane" "CAB002452: AB_564052, HPA006884: AB_1080566, HPA006885: AB_1080564" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.36e-1)" "unprognostic (3.03e-1)" "unprognostic (5.90e-2)" "unprognostic (2.44e-2)" "unprognostic (7.06e-2)" "unprognostic (4.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-1)" "unprognostic (2.58e-1)" "unprognostic (4.79e-2)" "unprognostic (4.65e-2)" VPS51 "ANG2, ANG3, C11orf2, C11orf3, FFR" ENSG00000149823 "VPS51 subunit of GARP complex" Q9UID3 11 65089324-65111862 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid transport, Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039650, HPA061447" Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 18: Non-specific - Ribosome" "Cluster 37: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 64: Non-specific - Ribosome" 2 "Golgi apparatus, Vesicles" Nucleoli "HPA039650: AB_10673147, HPA061447: AB_2684521" "unprognostic (2.36e-2)" "unprognostic (7.58e-2)" "unprognostic (8.35e-2)" "unprognostic (1.56e-1)" "unprognostic (2.11e-2)" "unprognostic (1.64e-1)" "unprognostic (9.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "prognostic favorable (2.41e-9)" "unprognostic (7.77e-3)" "unprognostic (4.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.18e-1)" WIPI2 "ATG18B, ATG21, CGI-50, DKFZP434J154, DKFZp686P02188, FLJ12979, FLJ14217, FLJ42984" ENSG00000157954 "WD repeat domain, phosphoinositide interacting 2" Q9Y4P8 7 5190196-5233840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 248.9;Spermatocytes: 228.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019852, HPA021488" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" 3 Cytosol Nucleoplasm "HPA019852: AB_1846589, HPA021488: AB_1846591" "unprognostic (5.79e-2)" "unprognostic (1.47e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (7.69e-5)" "unprognostic (1.96e-3)" "unprognostic (9.27e-3)" "unprognostic (4.60e-3)" "unprognostic (4.96e-2)" "unprognostic (6.60e-2)" "unprognostic (4.23e-1)" "prognostic favorable (9.78e-4)" "unprognostic (1.20e-1)" "prognostic favorable (2.05e-6)" "unprognostic (2.61e-2)" "unprognostic (1.37e-1)" "unprognostic (7.41e-2)" "unprognostic (6.98e-2)" XKRX "XKR2, XPLAC" ENSG00000182489 "XK related X-linked" Q6PP77 X 100913445-100929433 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.4;skin 1: 9.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 5.0;Alveolar cells type 2: 3.5;Astrocytes: 9.0;Excitatory neurons: 4.2;Inhibitory neurons: 5.8;Microglial cells: 3.6;Oligodendrocytes: 5.2;Syncytiotrophoblasts: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "naive B-cell: 1.9;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.2" "Group enriched" "Detected in many" 18 "B-cells: 1.9;T-cells: 1.5" "Low cancer specificity" "Detected in some" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 65: Neurons - Synaptic function" "unprognostic (3.35e-1)" "unprognostic (2.38e-2)" "unprognostic (4.51e-3)" "unprognostic (1.87e-1)" "unprognostic (8.53e-2)" "unprognostic (2.67e-2)" "unprognostic (2.96e-2)" "unprognostic (5.18e-2)" "unprognostic (3.69e-2)" "unprognostic (7.37e-2)" "unprognostic (5.70e-2)" "unprognostic (1.58e-2)" "unprognostic (5.60e-6)" "unprognostic (1.25e-1)" "unprognostic (2.60e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.18e-1)" ZBTB7B "c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B" ENSG00000160685 "Zinc finger and BTB domain containing 7B" O15156 1 155002630-155018523 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 118.8;Proximal enterocytes: 141.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006811, HPA025820" Enhanced Enhanced Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 13: Skin - Cornification" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 5: Enterocytes - Absorption" 11 Nucleoplasm "HPA006811: AB_1859046, HPA025820: AB_1859045" "unprognostic (5.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (4.36e-2)" "unprognostic (2.43e-1)" "unprognostic (4.95e-3)" "unprognostic (9.55e-2)" "unprognostic (1.41e-1)" "unprognostic (3.72e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.46e-2)" "unprognostic (5.35e-2)" "unprognostic (1.11e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" "unprognostic (1.53e-2)"