Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" AQP12A AQP12 ENSG00000184945 "Aquaporin 12A" Q8IXF9 2 240691866-240698483 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 326 "pancreas: 101.9" "Cell type enhanced" "Detected in single" "Proximal enterocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042216 Supported NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" "HPA042216: AB_2677905" "unprognostic (9.82e-2)" "unprognostic (1.63e-2)" "unprognostic (9.48e-2)" "unprognostic (2.14e-1)" LCT ENSG00000115850 Lactase P09848 2 135787850-135837184 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 186 "intestine: 219.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.9;Breast myoepithelial cells: 3.5;Early spermatids: 1.6;Erythroid cells: 1.1;Proximal enterocytes: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 15 "hippocampal formation: 15.8" "Not detected" "Not detected" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 59: Leukemia - T-cell receptor" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (2.21e-2)" "unprognostic (1.65e-4)" "unprognostic (2.54e-1)" "unprognostic (2.06e-1)" "unprognostic (3.39e-2)" "unprognostic (8.03e-4)" "unprognostic (3.55e-3)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (3.57e-1)" "unprognostic (1.69e-1)" "unprognostic (9.32e-2)" "unprognostic (1.64e-4)" "unprognostic (4.90e-2)" "unprognostic (8.92e-2)" "unprognostic (8.97e-2)" "unprognostic (1.02e-1)" SULT1C3 ENSG00000196228 "Sulfotransferase family 1C member 3" Q6IMI6 2 108239968-108265351 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 64 "breast: 276.6" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 1.8;Proximal enterocytes: 1.9" "Cancer enriched" "Detected in some" 4 "breast cancer: 2.4" "Region enhanced" "Detected in single" "choroid plexus: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.6;Gastric cancer: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA060368 Approved Cytosol NA NA "Cluster 73: Breast - Lactation" "Cluster 3: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 Cytosol "HPA060368: " "unprognostic (1.14e-3)" "unprognostic (1.78e-1)" "unprognostic (4.13e-1)" "unprognostic (6.64e-2)" GUCA2A "GUCA2, STARA" ENSG00000197273 "Guanylate cyclase activator 2A" Q02747 1 42162690-42164745 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "intestine: 901.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4872.7;Paneth cells: 22598.0;Proximal enterocytes: 11340.5" "Group enriched" "Detected in many" 7 "colorectal cancer: 31.6;urothelial cancer: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 11.2" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA018215 Enhanced "Secreted to blood" "No annotated function" NA NA 18000000 "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 9 "HPA018215: AB_1850443" "unprognostic (7.98e-3)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (9.07e-2)" "unprognostic (1.14e-1)" "unprognostic (8.06e-2)" "unprognostic (2.89e-1)" "unprognostic (3.10e-1)" "unprognostic (9.15e-2)" ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 52 "intestine: 30.6;liver: 61.9" "Cell type enhanced" "Detected in some" "Hepatocytes: 67.5;Oocytes: 10.3;Paneth cells: 16.2;Proximal enterocytes: 33.9" "Cancer enriched" "Detected in some" 30 "liver cancer: 21.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 Vesicles "HPA019556: AB_1844444" "unprognostic (1.99e-1)" "unprognostic (4.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.37e-1)" "unprognostic (3.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (6.28e-1)" "unprognostic (6.14e-3)" "unprognostic (4.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-3)" "unprognostic (5.03e-1)" "unprognostic (1.50e-1)" NAT2 AAC2 ENSG00000156006 "N-acetyltransferase 2" P11245 8 18391282-18401218 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 42 "intestine: 32.5;liver: 124.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 18.2;Hepatocytes: 62.5;Intestinal goblet cells: 10.3;Paneth cells: 15.1;Proximal enterocytes: 35.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0;liver cancer: 4.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 2.2" "Colon - Colon enterocytes" HPA043704 Uncertain NA NA "Cluster 83: Liver - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" 2 "HPA043704: AB_2678625" "unprognostic (2.74e-3)" "unprognostic (4.03e-1)" "prognostic favorable (4.61e-5)" "unprognostic (1.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.52e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-3)" "unprognostic (1.02e-1)" "unprognostic (3.40e-1)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" MTTP "ABL, MTP" ENSG00000138823 "Microsomal triglyceride transfer protein" P55157 4 99564081-99623997 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 267.5;liver: 258.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 206.9;Muller glia cells: 127.4;Proximal enterocytes: 560.1" "Cancer enriched" "Detected in many" 13 "liver cancer: 28.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Gastric cancer: 5.1;liver cancer: 18.2" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA051170, HPA054862" Uncertain Approved "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" Transport NA NA 640000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 1 "Endoplasmic reticulum, Cytosol" "HPA051170: , HPA054862: AB_2682628" "unprognostic (1.66e-2)" "unprognostic (1.14e-1)" "unprognostic (5.64e-2)" "unprognostic (5.33e-2)" "unprognostic (3.49e-3)" "unprognostic (7.38e-2)" "unprognostic (1.05e-1)" "unprognostic (2.74e-2)" "unprognostic (1.08e-1)" "unprognostic (3.66e-2)" "unprognostic (1.00e-2)" "unprognostic (1.62e-1)" "unprognostic (1.27e-3)" "unprognostic (2.02e-2)" "unprognostic (3.64e-1)" "unprognostic (1.53e-2)" "unprognostic (1.31e-1)" MOGAT2 "DGAT2L5, FLJ22644, MGAT2" ENSG00000166391 "Monoacylglycerol O-acyltransferase 2" Q3SYC2 11 75717838-75732958 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "intestine: 46.9;liver: 24.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 67.6;Hepatocytes: 67.9;Intestinal goblet cells: 32.2;Paneth cells: 21.3;Proximal enterocytes: 147.4;Undifferentiated cells: 19.7" "Cancer enhanced" "Detected in many" "liver cancer: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA028834 Uncertain NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA028834: AB_10601865" "unprognostic (5.63e-2)" "unprognostic (2.71e-2)" "unprognostic (6.37e-2)" "unprognostic (6.88e-3)" "unprognostic (1.15e-4)" "unprognostic (2.66e-3)" "unprognostic (1.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.42e-2)" "unprognostic (1.12e-1)" "unprognostic (4.21e-2)" "unprognostic (3.02e-1)" "unprognostic (1.24e-5)" "unprognostic (2.13e-3)" "unprognostic (1.84e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-3)" TMEM236 "bA162I21.2, bA16O1.2, FAM23A, FAM23B" ENSG00000148483 "Transmembrane protein 236" Q5W0B7 10 17752201-17800868 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 32.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 63.4;Enteroendocrine cells: 25.5;Intestinal goblet cells: 32.8;Paneth cells: 29.4;Proximal enterocytes: 91.3" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.7;pancreatic cancer: 0.5;stomach cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 1.3;Rhabdoid: 1.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045096 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 6: Leukemia - Signal transduction" "Cluster 5: Enterocytes - Absorption" 4 "HPA045096: AB_2732516" "unprognostic (4.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.88e-3)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (3.36e-2)" "unprognostic (2.52e-3)" "unprognostic (1.37e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (5.06e-3)" "unprognostic (1.75e-1)" "unprognostic (1.62e-2)" "unprognostic (1.72e-1)" "unprognostic (3.43e-2)" "unprognostic (3.16e-2)" "unprognostic (1.54e-2)" DISP2 "C15orf36, DISPB, HsT16908, KIAA1742, LINC00594" ENSG00000140323 "Dispatched RND transporter family member 2" A7MBM2 15 40358219-40378621 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "brain: 27.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.7;Distal enterocytes: 21.6;Enteroendocrine cells: 14.6;Horizontal cells: 34.6;Intestinal goblet cells: 18.1;Proximal enterocytes: 12.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059903 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 16: Intestinal goblet cells - Mucin production" "Nucleoplasm, Vesicles" "HPA059903: AB_2684156" "unprognostic (3.43e-4)" "unprognostic (7.65e-3)" "unprognostic (4.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.90e-1)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (3.08e-2)" "unprognostic (1.98e-1)" "unprognostic (2.13e-2)" "unprognostic (1.45e-1)" "unprognostic (6.75e-2)" "unprognostic (4.47e-8)" "unprognostic (1.96e-1)" "unprognostic (3.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.71e-1)" AOC1 "ABP, ABP1, DAO" ENSG00000002726 "Amine oxidase copper containing 1" P19801 7 150824627-150861504 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Heparin-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 221.1;kidney: 131.7;placenta: 479.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 241.2;Distal enterocytes: 377.7;Intestinal goblet cells: 116.8;Paneth cells: 304.1;Proximal enterocytes: 876.3" "Group enriched" "Detected in many" 5 "colorectal cancer: 61.3;endometrial cancer: 39.1;pancreatic cancer: 26.9;renal cancer: 69.4;stomach cancer: 43.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 12 "eosinophil: 31.3" "Lineage enriched" "Detected in many" 22 "granulocytes: 31.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 48.4" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031032, HPA031033" Approved "Secreted in other tissues" Enzyme NA NA 2500000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 45: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 8 "HPA031032: AB_10670150, HPA031033: AB_10669670" "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (1.58e-2)" "unprognostic (2.84e-2)" "unprognostic (6.31e-3)" "unprognostic (8.31e-3)" "unprognostic (9.07e-3)" "unprognostic (6.42e-2)" "unprognostic (1.21e-1)" "unprognostic (1.96e-1)" "unprognostic (3.11e-1)" "prognostic favorable (1.71e-4)" "unprognostic (5.32e-3)" "unprognostic (3.62e-2)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" BTNL8 "BTN9.2, FLJ21458" ENSG00000113303 "Butyrophilin like 8" Q6UX41 5 180899077-180950906 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "intestine: 115.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 73.9;Intestinal goblet cells: 36.0;Paneth cells: 38.9;Proximal enterocytes: 189.8" "Group enriched" "Detected in some" 12 "colorectal cancer: 2.6;liver cancer: 1.5;pancreatic cancer: 2.8;stomach cancer: 3.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 12 "neutrophil: 234.3" "Lineage enriched" "Detected in many" 221 "granulocytes: 234.3" "Group enriched" "Detected in some" 5 "colorectal cancer: 3.8;Esophageal cancer: 1.8;Gastric cancer: 3.5;pancreatic cancer: 2.0" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA039738 Enhanced NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "HPA039738: AB_2676656" "unprognostic (4.31e-1)" "unprognostic (6.85e-6)" "unprognostic (6.99e-2)" "unprognostic (1.48e-1)" "unprognostic (6.33e-2)" "unprognostic (1.91e-1)" "unprognostic (6.27e-3)" "unprognostic (6.07e-2)" "unprognostic (3.08e-3)" "unprognostic (3.28e-1)" "unprognostic (1.67e-1)" "unprognostic (9.02e-2)" "unprognostic (4.96e-3)" "unprognostic (2.93e-1)" "unprognostic (1.42e-1)" "unprognostic (4.43e-1)" "unprognostic (1.17e-2)" CHP2 ENSG00000166869 "Calcineurin like EF-hand protein 2" O43745 16 23755026-23758935 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 296.3;skin 1: 145.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 399.7;Paneth cells: 281.4;Proximal enterocytes: 665.0;Undifferentiated cells: 150.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 8.6;Bladder cancer: 6.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055198, CAB072806" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 2 Nucleoplasm "Nucleoli, Cytosol" "CAB072806: , HPA055198: " "unprognostic (4.82e-1)" "unprognostic (3.40e-1)" "unprognostic (4.93e-2)" "unprognostic (1.01e-2)" "unprognostic (8.85e-2)" "unprognostic (3.54e-1)" "unprognostic (4.54e-2)" "unprognostic (1.47e-1)" "unprognostic (1.38e-1)" "unprognostic (5.31e-2)" "unprognostic (4.70e-2)" "unprognostic (1.44e-5)" "unprognostic (2.21e-1)" "unprognostic (5.97e-2)" "unprognostic (7.84e-2)" "unprognostic (9.01e-2)" ADGRG7 "FLJ14454, GPR128" ENSG00000144820 "Adhesion G protein-coupled receptor G7" Q96K78 3 100609601-100695479 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "intestine: 41.7;liver: 24.0" "Cell type enhanced" "Detected in some" "Hepatocytes: 22.4;Intestinal goblet cells: 9.5;Paneth cells: 20.1;Proximal enterocytes: 34.0" "Cancer enhanced" "Detected in some" "stomach cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.8;Brain cancer: 1.3" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056451 Approved "Plasma membrane" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 3 "Plasma membrane" "HPA056451: " "unprognostic (1.65e-1)" "unprognostic (1.10e-1)" "unprognostic (2.79e-1)" "unprognostic (8.46e-3)" "unprognostic (1.26e-1)" "unprognostic (6.71e-2)" "unprognostic (9.37e-3)" "unprognostic (2.84e-5)" "unprognostic (1.17e-1)" "unprognostic (2.16e-1)" "unprognostic (6.77e-2)" IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 458.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 13.4;Distal enterocytes: 19.9;Hepatocytes: 24.3;Intestinal goblet cells: 27.4;Paneth cells: 17.1;Proximal enterocytes: 76.2;Proximal tubular cells: 28.7" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.8;Gastric cancer: 2.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Thyroid gland - Unknown function" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane" "HPA059627: AB_2684086" "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" PHGR1 ENSG00000233041 "Proline, histidine and glycine rich 1" C9JFL3 15 40351033-40356434 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 2471.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 66526.7;Enteroendocrine cells: 8087.3;Intestinal goblet cells: 12406.1;Paneth cells: 19242.8;Proximal enterocytes: 47949.6" "Group enriched" "Detected in many" 16 "colorectal cancer: 248.3;stomach cancer: 94.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 203.2;colorectal cancer: 705.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA068787 Enhanced Approved Vesicles NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA068787: AB_2686035" "prognostic favorable (2.05e-4)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (1.18e-1)" "unprognostic (2.80e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-2)" PRODH "HSPOX2, PIG6, PRODH1, PRODH2, TP53I6" ENSG00000277196 "Proline dehydrogenase 1" Unmapped 138082-161852 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 14 "choroid plexus: 463.0" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.1;Ionocytes: 1.8;Melanocytes: 3.4;Proximal enterocytes: 4.9;Proximal tubular cells: 1.5;Squamous epithelial cells: 2.3;Suprabasal keratinocytes: 1.7" "Region enriched" "Detected in all" 5 "choroid plexus: 350.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 37.0" HPA020361 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "Nucleoplasm, Vesicles" "HPA020361: AB_10963116" URAD PRHOXNB ENSG00000183463 "Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase" A6NGE7 13 27977717-27988693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Purine metabolism" "Decarboxylase, Lyase" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 14 "intestine: 24.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 69.0;Enteroendocrine cells: 60.8;Intestinal goblet cells: 111.0;Paneth cells: 53.3;Proximal enterocytes: 204.7;Undifferentiated cells: 48.5" "Cancer enriched" "Detected in some" 15 "colorectal cancer: 7.4" "Region enriched" "Detected in single" 4 "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "colorectal cancer: 2.9;liver cancer: 1.3" "Colon - Colon enterocytes, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Low region specificity" "Detected in many" HPA038972 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA038972: AB_10671869" "unprognostic (2.00e-1)" "unprognostic (1.05e-1)" "unprognostic (5.21e-2)" VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 423.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 262.9;Enteroendocrine cells: 134.4;Intestinal goblet cells: 144.6;Paneth cells: 211.1;Proximal enterocytes: 583.3;Undifferentiated cells: 133.2" "Group enriched" "Detected in many" 4 "colorectal cancer: 56.4;stomach cancer: 23.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in many" 5 "Bile duct cancer: 128.5;colorectal cancer: 290.7;Gastric cancer: 138.2;liver cancer: 154.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA 6800 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane" "CAB002452: AB_564052, HPA006884: AB_1080566, HPA006885: AB_1080564" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.36e-1)" "unprognostic (3.03e-1)" "unprognostic (5.90e-2)" "unprognostic (2.44e-2)" "unprognostic (7.06e-2)" "unprognostic (4.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-1)" "unprognostic (2.58e-1)" "unprognostic (4.79e-2)" "unprognostic (4.65e-2)" CHST5 "FLJ22167, I-GLCNAC-6-ST" ENSG00000135702 "Carbohydrate sulfotransferase 5" Q9GZS9 16 75528530-75536108 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 84.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4.8;Enteroendocrine cells: 6.2;Excitatory neurons: 2.1;Intestinal goblet cells: 6.1;Paneth cells: 3.2;Proximal enterocytes: 9.8" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.4;stomach cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.4" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells" "HPA043804, HPA068029" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA043804: AB_10960563, HPA068029: " "unprognostic (6.82e-3)" "unprognostic (2.02e-1)" "unprognostic (1.99e-3)" "unprognostic (1.03e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-2)" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (2.09e-2)" "unprognostic (9.03e-3)" "unprognostic (4.27e-2)" "unprognostic (2.05e-3)" "unprognostic (3.56e-1)" "unprognostic (2.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.42e-2)" FABP1 L-FABP ENSG00000163586 "Fatty acid binding protein 1" P07148 2 88122982-88128062 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "intestine: 5302.5;liver: 12622.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 32960.0;Hepatocytes: 8556.6;Paneth cells: 7388.8;Proximal enterocytes: 18313.5" "Group enriched" "Detected in many" 14 "colorectal cancer: 175.1;liver cancer: 437.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 408.0;colorectal cancer: 909.1;liver cancer: 309.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB002305, HPA028275" Enhanced Approved Nucleoplasm,Cytosol NA NA 45000000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Nucleoplasm, Cytosol" "CAB002305: AB_563728, HPA028275: AB_10600909" "unprognostic (1.91e-1)" "unprognostic (7.91e-3)" "unprognostic (5.47e-2)" "unprognostic (1.96e-1)" "unprognostic (2.03e-2)" "unprognostic (2.35e-1)" "unprognostic (7.99e-2)" "unprognostic (8.92e-2)" "unprognostic (2.29e-1)" OTOP3 ENSG00000182938 "Otopetrin 3" 17 74935898-74949992 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "intestine: 77.4" "Cell type enhanced" "Detected in some" "Paneth cells: 70.0;Proximal enterocytes: 14.0;Squamous epithelial cells: 7.4;Suprabasal keratinocytes: 21.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cervical cancer: 27.4;thyroid cancer: 9.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "unprognostic (9.28e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.77e-1)" "unprognostic (8.60e-2)" "unprognostic (3.42e-1)" "unprognostic (1.03e-1)" "unprognostic (8.36e-2)" ZNF488 FLJ32104 ENSG00000265763 "Zinc finger protein 488" Q96MN9 10 47365496-47384293 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 61.9;intestine: 21.8" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.6;Distal tubular cells: 12.3;Horizontal cells: 6.9;Oligodendrocyte precursor cells: 9.4;Oligodendrocytes: 18.7;Proximal enterocytes: 19.8;Syncytiotrophoblasts: 33.6" "Cancer enhanced" "Detected in many" "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035957, HPA035958" Supported Nucleoplasm,Cytosol "Intracellular and membrane" Transcription NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" 10 "Nucleoplasm, Cytosol" "HPA035957: AB_10672234, HPA035958: AB_2674887" "unprognostic (3.29e-2)" "unprognostic (1.05e-2)" "unprognostic (7.87e-2)" "unprognostic (1.49e-4)" "unprognostic (1.16e-1)" "unprognostic (8.85e-2)" "unprognostic (1.60e-3)" "unprognostic (2.13e-2)" "unprognostic (3.11e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (4.02e-7)" "unprognostic (3.60e-1)" "unprognostic (6.62e-5)" "unprognostic (2.76e-1)" "unprognostic (4.47e-1)" "unprognostic (8.10e-2)" "unprognostic (3.18e-2)" CATSPERG "C19orf15, DKFZp434A1022, FLJ46353" ENSG00000099338 "Cation channel sperm associated auxiliary subunit gamma" Q6ZRH7 19 38335775-38370943 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 30.5" "Cell type enhanced" "Detected in many" "Early spermatids: 25.1;Gastric mucus-secreting cells: 22.4;Late spermatids: 47.2;Proximal enterocytes: 18.4;Spermatocytes: 25.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA052777 Approved Nucleoplasm,Nucleoli,Cytosol "Secreted in male reproductive system" "Developmental protein" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 42: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Late spermatids - Spermatogenesis" Nucleoli "Nucleoplasm, Cytosol" "HPA052777: " "unprognostic (8.50e-5)" "unprognostic (5.12e-2)" "unprognostic (3.57e-3)" "unprognostic (1.51e-1)" "unprognostic (2.63e-1)" "unprognostic (3.18e-1)" "unprognostic (2.60e-1)" "unprognostic (2.87e-3)" "unprognostic (1.00e-1)" "unprognostic (2.92e-2)" "unprognostic (1.06e-1)" "unprognostic (2.50e-1)" "unprognostic (4.37e-4)" "unprognostic (9.99e-2)" "unprognostic (2.01e-1)" "unprognostic (4.61e-2)" "unprognostic (1.07e-3)" KHK ENSG00000138030 Ketohexokinase P50053 2 27086772-27100762 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "intestine: 122.9;kidney: 104.7;liver: 179.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 387.6;Proximal enterocytes: 1881.3;Proximal tubular cells: 741.7" "Group enriched" "Detected in all" 7 "liver cancer: 62.2;renal cancer: 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007040 Enhanced Approved Vesicles,Cytosol NA NA 620000 "Cluster 33: Non-specific - ATP binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 1 "Vesicles, Cytosol" "HPA007040: AB_1079185" "unprognostic (8.44e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.62e-8)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (3.13e-2)" "unprognostic (1.67e-2)" "unprognostic (2.50e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.68e-2)" "unprognostic (2.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" GLYCTK "HBEBP2, HBEBP4" ENSG00000168237 "Glycerate kinase" Q8IVS8 3 52287089-52295257 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 268.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 184.8;Proximal enterocytes: 113.3;Proximal tubular cells: 77.9" "Cancer enriched" "Detected in all" 6 "liver cancer: 52.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006913 Approved Approved "Golgi apparatus,Cytosol,Rods & Rings" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 43: Hepatocytes - Metabolism" 48 Cytosol "Golgi apparatus, Rods & Rings" "HPA006913: AB_1078993" "unprognostic (1.51e-2)" "unprognostic (2.55e-1)" "unprognostic (1.25e-1)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.64e-4)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (7.73e-3)" "unprognostic (1.82e-1)" "unprognostic (3.36e-3)" "unprognostic (2.15e-1)" "unprognostic (3.30e-2)" "unprognostic (3.42e-1)" "unprognostic (3.77e-1)" "unprognostic (3.82e-2)" "unprognostic (9.00e-3)" NLRP6 "CLR11.4, NALP6, PAN3, PYPAF5" ENSG00000174885 "NLR family pyrin domain containing 6" P59044 11 278407-285388 "Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 38.8" "Cell type enhanced" "Detected in some" "B-cells: 1.4;monocytes: 2.0;Proximal enterocytes: 9.6;T-cells: 3.8" "Group enriched" "Detected in some" 4 "colorectal cancer: 0.9;liver cancer: 1.2;renal cancer: 1.5;stomach cancer: 1.8" "Region enriched" "Detected in many" 5 "cerebral cortex: 8.4" "Group enriched" "Detected in many" 4 "neutrophil: 15.5;non-classical monocyte: 4.6" "Group enriched" "Detected in many" 4 "granulocytes: 15.5;monocytes: 4.6" "Cancer enhanced" "Detected in some" "Leukemia: 1.2;Myeloma: 2.1" "Adipose visceral - Neutrophils, Kidney - Proximal tubular cells, Lung - Neutrophil_2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043681, HPA048500" Supported NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: T-cells - T-cell receptor" "HPA043681: AB_2678614, HPA048500: AB_2680422" "unprognostic (6.37e-3)" "unprognostic (4.69e-2)" "unprognostic (4.26e-2)" "unprognostic (3.42e-2)" "unprognostic (6.40e-2)" "unprognostic (1.18e-2)" "prognostic favorable (4.23e-5)" "unprognostic (8.82e-2)" "unprognostic (2.40e-1)" "unprognostic (1.66e-1)" "unprognostic (5.16e-3)" "unprognostic (2.19e-1)" "unprognostic (3.11e-3)" "unprognostic (4.96e-2)" "unprognostic (2.14e-2)" "unprognostic (6.90e-3)" "unprognostic (3.69e-2)" SLC51A OSTalpha ENSG00000163959 "Solute carrier family 51 subunit alpha" Q86UW1 3 196211487-196243178 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "intestine: 62.7;liver: 69.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 72.0;Leydig cells: 62.4;Peritubular cells: 102.4;Proximal enterocytes: 314.1;Sertoli cells: 62.6" "Cancer enriched" "Detected in many" 7 "liver cancer: 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045488 Enhanced NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 5: Enterocytes - Absorption" 2 "HPA045488: " "unprognostic (1.63e-2)" "unprognostic (1.27e-3)" "unprognostic (2.80e-1)" "unprognostic (7.66e-2)" "unprognostic (5.16e-2)" "unprognostic (2.40e-2)" "prognostic favorable (7.54e-4)" "unprognostic (5.02e-2)" "unprognostic (1.07e-1)" "unprognostic (5.98e-3)" "unprognostic (5.41e-2)" "unprognostic (2.90e-2)" "unprognostic (2.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-5)" FMO1 ENSG00000010932 "Flavin containing dimethylaniline monoxygenase 1" Q01740 1 171248471-171285978 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "kidney: 191.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 27.7;Mesothelial cells: 59.0;Proximal enterocytes: 85.9;Proximal tubular cells: 165.1" "Cancer enriched" "Detected in many" 8 "renal cancer: 18.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Rhabdoid: 1.4" "Kidney - Proximal tubular cells, Lung - Fibroblast_2, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078132 Approved NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 5 "HPA078132: " "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (5.87e-2)" "unprognostic (1.34e-1)" "unprognostic (5.32e-3)" "unprognostic (1.89e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "unprognostic (9.16e-2)" "unprognostic (9.03e-2)" "unprognostic (1.36e-2)" "unprognostic (2.23e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.49e-4)" "unprognostic (1.40e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" LGALS4 GAL4 ENSG00000171747 "Galectin 4" P56470 19 38801671-38812945 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "intestine: 1271.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 11586.4;Enteroendocrine cells: 3400.6;Intestinal goblet cells: 5852.5;Paneth cells: 4816.3;Proximal enterocytes: 4964.5;Undifferentiated cells: 2802.8" "Group enriched" "Detected in many" 21 "colorectal cancer: 450.7;liver cancer: 133.6;pancreatic cancer: 213.7;stomach cancer: 190.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 304.6;Gastric cancer: 203.9" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB025653, HPA031184, HPA031185, HPA031186" Enhanced Uncertain "Plasma membrane" NA NA 200000 "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 6 "Plasma membrane" "CAB025653: , HPA031184: AB_2673776, HPA031185: AB_2673777, HPA031186: AB_2673778" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (2.57e-3)" "unprognostic (7.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (1.54e-1)" "unprognostic (7.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.69e-1)" "unprognostic (3.38e-1)" "unprognostic (9.71e-2)" "prognostic favorable (3.21e-4)" MST1 "D3F15S2, DNF15S2, HGFL, MSP, NF15S2" ENSG00000173531 "Macrophage stimulating 1" 3 49683947-49689501 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 10 "liver: 905.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 196.0;Mesothelial cells: 44.6;Proximal enterocytes: 54.0;Proximal tubular cells: 42.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 42.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024036, HPA068514, CAB080358" Approved Approved Vesicles "Secreted to blood" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" Vesicles "CAB080358: , HPA024036: AB_1854147, HPA068514: " "unprognostic (5.13e-3)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-1)" "unprognostic (2.00e-2)" "unprognostic (1.16e-2)" "unprognostic (9.42e-3)" "unprognostic (8.24e-2)" "unprognostic (2.97e-1)" "prognostic favorable (7.14e-4)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.11e-1)" "unprognostic (2.48e-1)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" MUC13 DRCC1 ENSG00000173702 "Mucin 13, cell surface associated" Q9H3R2 3 124905442-124953819 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "intestine: 597.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 500.9;Enteroendocrine cells: 161.4;Intestinal goblet cells: 447.1;Paneth cells: 323.4;Proximal enterocytes: 400.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 198.4;stomach cancer: 152.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 178.0;Gastric cancer: 65.7" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045163, HPA079663" Enhanced "Secreted to digestive system" "No annotated function" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA045163: AB_10960396, HPA079663: " "unprognostic (8.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-3)" "unprognostic (2.93e-1)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-2)" "unprognostic (2.94e-1)" "unprognostic (5.10e-2)" "unprognostic (2.02e-1)" "unprognostic (9.64e-2)" "prognostic unfavorable (9.73e-5)" "unprognostic (2.05e-3)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" UNC93A "dJ366N23.1, dJ366N23.2" ENSG00000112494 "Unc-93 homolog A" Q86WB7 6 167271169-167316014 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "esophagus: 4.9;intestine: 9.3;liver: 13.6;skin 1: 18.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 11.7;Hepatocytes: 6.2;Oocytes: 30.1;Proximal enterocytes: 3.4" "Cancer enhanced" "Detected in many" "liver cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "colorectal cancer: 6.8;Gastric cancer: 7.1;liver cancer: 3.5" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA035729 Uncertain NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 44: Oocytes - Unknown function" "HPA035729: AB_10696508" "unprognostic (2.49e-1)" "unprognostic (2.67e-1)" "unprognostic (2.32e-1)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (2.26e-1)" "unprognostic (2.32e-1)" "unprognostic (2.10e-1)" "unprognostic (3.32e-3)" "unprognostic (2.99e-2)" "unprognostic (5.97e-3)" "unprognostic (1.85e-1)" "unprognostic (4.92e-2)" HNF1A "HNF1, HNF1alpha, LFB1, MODY3, TCF1" ENSG00000135100 "HNF1 homeobox A" 12 120978543-121002512 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 13.7;kidney: 8.4;liver: 10.9;pancreas: 4.8;stomach 1: 3.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 8.3;Hepatocytes: 14.3;Intestinal goblet cells: 12.4;Oocytes: 25.7;Paneth cells: 16.0;Proximal enterocytes: 31.1;Proximal tubular cells: 14.3;Undifferentiated cells: 10.3" "Group enriched" "Detected in many" 4 "colorectal cancer: 4.5;liver cancer: 3.6;pancreatic cancer: 1.4;renal cancer: 3.6;stomach cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 14.9;Gastric cancer: 9.8;liver cancer: 18.1" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010430, HPA035231" Enhanced Supported Nucleoplasm NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm "CAB010430: AB_2116746, HPA035231: AB_2674528" "unprognostic (5.92e-3)" "unprognostic (8.47e-2)" "unprognostic (4.12e-3)" "unprognostic (6.18e-3)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (9.18e-2)" "unprognostic (9.18e-2)" "unprognostic (2.99e-1)" "unprognostic (2.01e-1)" "unprognostic (9.77e-3)" "unprognostic (5.21e-2)" "unprognostic (6.25e-3)" "unprognostic (5.55e-2)" "unprognostic (2.48e-1)" "unprognostic (6.93e-3)" MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 191.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 783.4;Intestinal goblet cells: 233.5;Paneth cells: 464.7;Proximal enterocytes: 1059.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 104.4" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 44 "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 104.5;skeletal muscle: 157.4;tongue: 46.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.1;Erythroid cells: 33.0;Exocrine glandular cells: 63.2;Horizontal cells: 59.2;Paneth cells: 39.8;Proximal enterocytes: 39.3;Skeletal myocytes: 80.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme NA NA 990000 "Cluster 79: Non-specific - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 3 "Golgi apparatus" Vesicles "HPA027098: AB_2672111" "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 118.6" "Cell type enhanced" "Detected in some" "Hepatocytes: 74.4;Oligodendrocyte precursor cells: 31.6;Oligodendrocytes: 35.8;Oocytes: 103.7;Proximal enterocytes: 25.5" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.4" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.2" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 43: Hepatocytes - Metabolism" 1 Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" B3GALT5 "B3GalT-V, B3T5, beta3Gal-T5, GLCT5" ENSG00000183778 "Beta-1,3-galactosyltransferase 5" Q9Y2C3 21 39556442-39673137 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "intestine: 44.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 144.4;Enteroendocrine cells: 35.4;Intestinal goblet cells: 62.6;Paneth cells: 62.1;Proximal enterocytes: 82.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 11.1;pancreatic cancer: 14.9" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 11.4" "HPA054092, HPA054684" Approved "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "HPA054092: AB_2682375, HPA054684: AB_2682573" "unprognostic (1.40e-2)" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "prognostic favorable (6.36e-4)" "unprognostic (9.23e-2)" "unprognostic (4.62e-2)" "unprognostic (4.06e-2)" "unprognostic (2.04e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.86e-3)" "unprognostic (1.67e-1)" "unprognostic (6.09e-4)" "unprognostic (1.12e-1)" "unprognostic (2.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.55e-3)" CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 98.4;stomach 1: 117.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 90.2;Intestinal goblet cells: 34.6;Langerhans cells: 82.1;Proximal enterocytes: 41.7;Schwann cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.8;myeloid DC: 84.5" "Group enriched" "Detected in many" 131 "dendritic cells: 84.5;monocytes: 24.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Heart muscle - Macrophages, Liver - Kupffer cells, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Small intestine - Absorption" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 28: Dendritic cells - Antigen presentation" 2 "Endoplasmic reticulum" "HPA049227: AB_2680681, HPA069248: AB_2732128" "unprognostic (1.49e-2)" "unprognostic (7.45e-2)" "unprognostic (2.45e-2)" "unprognostic (6.03e-2)" "unprognostic (3.93e-2)" "unprognostic (7.46e-2)" "unprognostic (1.27e-2)" "unprognostic (4.85e-2)" "unprognostic (2.18e-1)" "unprognostic (1.54e-2)" "unprognostic (6.25e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.02e-1)" "unprognostic (7.66e-2)" DHRS11 "MGC4172, SDR24C1" ENSG00000278535 "Dehydrogenase/reductase 11" Q6UWP2 17 36591879-36600804 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "intestine: 209.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 214.1;Distal enterocytes: 315.6;Paneth cells: 116.2;Proximal enterocytes: 533.9;Undifferentiated cells: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041226, HPA048236, HPA053623" Enhanced Approved "Golgi apparatus,Cytosol" "Secreted to digestive system" Enzyme NA NA 42000 "Cluster 25: Small intestine - Absorption" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" Cytosol "Golgi apparatus" "HPA041226: AB_2677372, HPA048236: AB_2680322, HPA053623: AB_2682209" "unprognostic (2.00e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.80e-2)" "unprognostic (3.67e-1)" "unprognostic (5.94e-2)" "unprognostic (1.33e-2)" "unprognostic (4.11e-2)" "prognostic favorable (3.24e-4)" "unprognostic (1.45e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" KCNJ13 "Kir1.4, Kir7.1, LCA16" ENSG00000115474 "Potassium inwardly rectifying channel subfamily J member 13" O60928 2 232765802-232776565 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cataract, Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 170.7;intestine: 88.7" "Cell type enhanced" "Detected in some" "Melanocytes: 29.2;Muller glia cells: 52.0;Proximal enterocytes: 219.0;Undifferentiated cells: 65.7" "Cancer enriched" "Detected in some" 5 "melanoma: 5.9" "Region enriched" "Detected in all" 15 "choroid plexus: 342.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.1" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051609 Approved "Nuclear membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" "Nuclear membrane" "HPA051609: " "unprognostic (4.29e-2)" "unprognostic (2.00e-1)" "unprognostic (2.69e-1)" "unprognostic (9.03e-5)" "unprognostic (1.17e-1)" "unprognostic (3.12e-2)" "unprognostic (2.26e-1)" "unprognostic (3.44e-2)" "unprognostic (1.40e-1)" "unprognostic (1.41e-1)" "unprognostic (4.90e-2)" "unprognostic (1.86e-2)" "unprognostic (2.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.82e-2)" "unprognostic (1.11e-2)" KCP "CRIM2, FLJ33365, NET67" ENSG00000135253 "Kielin cysteine rich BMP regulator" Q6ZWJ8 7 128862042-128910719 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "kidney: 16.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 54.5;Late spermatids: 32.2;Proximal enterocytes: 58.2;Skeletal myocytes: 215.7" "Cancer enhanced" "Detected in many" "renal cancer: 5.5" "Region enriched" "Detected in single" 4 "cerebellum: 3.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Gallbladder cancer: 13.0;Kidney cancer: 8.2" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "No annotated function" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Skeletal myocytes - Muscle contraction" "unprognostic (6.12e-2)" "unprognostic (5.49e-2)" "unprognostic (1.45e-3)" "unprognostic (6.33e-3)" "unprognostic (2.14e-1)" "unprognostic (5.24e-3)" "unprognostic (2.01e-3)" "unprognostic (3.25e-3)" "unprognostic (9.59e-2)" "unprognostic (1.52e-1)" "unprognostic (2.20e-3)" "unprognostic (6.46e-2)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (4.84e-2)" "unprognostic (7.64e-3)" MYO7B ENSG00000169994 "Myosin VIIB" Q6PIF6 2 127535683-127637729 "Predicted intracellular proteins" Differentiation "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "intestine: 76.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 94.5;Enteroendocrine cells: 33.7;Intestinal goblet cells: 59.2;Paneth cells: 51.7;Proximal enterocytes: 138.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7;naive B-cell: 5.9" "Group enriched" "Detected in many" 22 "B-cells: 5.9;dendritic cells: 2.6;monocytes: 5.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.1;Leukemia: 24.4" "Kidney - Proximal tubular cells, Liver - Vascular Endothelial cells, Pancreas - Ductal cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" HPA039131 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA039131: AB_10672771" "unprognostic (4.10e-3)" "unprognostic (3.81e-2)" "unprognostic (3.80e-2)" "unprognostic (2.23e-4)" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (2.07e-1)" "unprognostic (8.51e-2)" "unprognostic (3.76e-1)" "unprognostic (3.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.80e-2)" "unprognostic (8.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" NR1I2 "BXR, ONR1, PAR2, PXR, SXR" ENSG00000144852 "Nuclear receptor subfamily 1 group I member 2" O75469 3 119780484-119818487 "FDA approved drug targets, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 30.4;liver: 46.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 20.7;Hepatocytes: 25.9;Intestinal goblet cells: 6.6;Paneth cells: 9.6;Proximal enterocytes: 43.0;Undifferentiated cells: 7.9" "Group enriched" "Detected in some" 24 "colorectal cancer: 9.0;liver cancer: 5.7;pancreatic cancer: 2.6;stomach cancer: 2.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 15 "NK-cell: 2.9" "Lineage enriched" "Detected in single" 15 "NK-cells: 2.9" "Cancer enhanced" "Detected in some" "colorectal cancer: 5.3;Gastric cancer: 3.9" "Colon - Colon enterocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA029309, HPA055121, HPA073926" Supported Nucleoplasm NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 2 Nucleoplasm "HPA029309: AB_2672990, HPA055121: AB_2682703, HPA073926: AB_2686643" "unprognostic (6.76e-3)" "unprognostic (2.25e-1)" "unprognostic (5.84e-2)" "unprognostic (1.24e-4)" "unprognostic (4.51e-2)" "unprognostic (4.52e-2)" "unprognostic (4.03e-3)" "unprognostic (3.97e-2)" "unprognostic (5.78e-2)" "unprognostic (5.05e-2)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (5.51e-6)" "unprognostic (4.86e-1)" "unprognostic (6.95e-2)" "unprognostic (3.13e-1)" "unprognostic (6.12e-3)" SLC17A4 KIAA2138 ENSG00000146039 "Solute carrier family 17 member 4" Q9Y2C5 6 25754699-25781199 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "gallbladder: 15.7;intestine: 31.0;liver: 46.2;pancreas: 22.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 82.0;Distal enterocytes: 84.8;Hepatocytes: 33.9;Intestinal goblet cells: 19.7;Paneth cells: 36.5;Proximal enterocytes: 43.2" "Group enriched" "Detected in some" 6 "liver cancer: 11.0;renal cancer: 7.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 3.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "cerebellum: 1.8" HPA055564 Approved NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 35: Non-specific - DNA binding" "Cluster 60: Prostate cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" "HPA055564: AB_2682852" "unprognostic (6.52e-2)" "unprognostic (5.64e-3)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (1.19e-3)" "unprognostic (1.40e-1)" "unprognostic (1.38e-1)" "unprognostic (7.27e-3)" ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983340-51989197 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "intestine: 176.3;kidney: 434.0;liver: 266.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Gastric mucus-secreting cells: 31.2;Proximal enterocytes: 137.7;Proximal tubular cells: 100.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003695, HPA036174, HPA036175, HPA071834" Enhanced Approved Vesicles NA NA 23000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 7 Vesicles "CAB003695: AB_425286, HPA036174: AB_2674988, HPA036175: AB_2674989, HPA071834: " "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-3)" "unprognostic (3.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.08e-2)" "unprognostic (2.36e-2)" "unprognostic (2.70e-2)" "prognostic favorable (2.93e-4)" "unprognostic (3.57e-1)" "unprognostic (3.75e-1)" "unprognostic (7.88e-2)" "prognostic favorable (6.77e-4)" AICDA "AID, ARP2, CDA2, HIGM2" ENSG00000111732 "Activation induced cytidine deaminase" Q9GZX7 12 8602155-8613242 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 11.0" "Cell type enhanced" "Detected in some" "B-cells: 1.3;monocytes: 1.3;Pancreatic endocrine cells: 1.7;Proximal enterocytes: 2.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.1" "Lineage enriched" "Detected in single" 4 "B-cells: 2.1" "Cancer enriched" "Detected in some" 15 "lymphoma: 25.6" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 11: White matter - Signal transduction" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 7 "unprognostic (2.71e-2)" "unprognostic (1.39e-2)" "unprognostic (7.76e-2)" "unprognostic (1.68e-1)" "unprognostic (8.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.05e-2)" "unprognostic (9.69e-2)" "unprognostic (1.96e-2)" "unprognostic (4.04e-6)" "unprognostic (8.82e-2)" "unprognostic (1.28e-1)" "unprognostic (4.21e-1)" "unprognostic (4.65e-1)" ANKS4B "FLJ38819, HARP" ENSG00000175311 "Ankyrin repeat and sterile alpha motif domain containing 4B" Q8N8V4 16 21233699-21253850 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 11.9;kidney: 5.7;liver: 13.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 54.5;Enteroendocrine cells: 38.1;Hepatocytes: 25.5;Intestinal goblet cells: 44.1;Paneth cells: 34.3;Proximal enterocytes: 104.4;Proximal tubular cells: 27.0;Undifferentiated cells: 21.6" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.2;liver cancer: 5.1;pancreatic cancer: 3.2;renal cancer: 3.3;stomach cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6;Gastric cancer: 3.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA043523, HPA061125" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 1 "Nucleoplasm, Cytosol" "HPA043523: AB_10966687, HPA061125: " "unprognostic (1.35e-1)" "unprognostic (4.96e-2)" "unprognostic (2.73e-2)" "unprognostic (3.32e-2)" "unprognostic (8.42e-3)" "unprognostic (8.61e-2)" "unprognostic (2.36e-1)" "unprognostic (9.48e-2)" "unprognostic (2.04e-1)" "unprognostic (4.08e-1)" "unprognostic (1.08e-1)" "unprognostic (9.75e-4)" "unprognostic (5.15e-3)" "unprognostic (1.88e-1)" "unprognostic (4.77e-2)" "unprognostic (4.34e-3)" ARHGDIG RHOGDI-3 ENSG00000242173 "Rho GDP dissociation inhibitor gamma" Q99819 16 280450-283010 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 247.8;pancreas: 109.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 26.9;Inhibitory neurons: 30.7;Proximal enterocytes: 64.3" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 15.2" "Breast - Adipocytes (Breast), Colon - Enteric glia cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078260 Approved "Plasma membrane,Cytosol" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 22: Proximal enterocytes - Digestion" 4 "Plasma membrane, Cytosol" "HPA078260: AB_2732375" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (7.98e-2)" "unprognostic (2.66e-2)" "unprognostic (9.04e-2)" "unprognostic (2.13e-2)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-2)" "unprognostic (3.18e-1)" "unprognostic (2.94e-1)" "unprognostic (5.86e-6)" "unprognostic (2.81e-2)" "unprognostic (4.34e-1)" "unprognostic (2.15e-1)" "unprognostic (6.32e-2)" CASP5 ICE(rel)III ENSG00000137757 "Caspase 5" P51878 11 104994235-105023168 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 16.3;lymphoid tissue: 14.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 21.2;Kupffer cells: 5.5;monocytes: 18.9;Paneth cells: 6.2;Proximal enterocytes: 19.1" "Group enriched" "Detected in some" 7 "colorectal cancer: 3.9;stomach cancer: 1.3" "Group enriched" "Detected in some" 5 "cerebral cortex: 9.1;pons: 2.3" "Group enriched" "Detected in some" 13 "intermediate monocyte: 18.1;neutrophil: 13.0;non-classical monocyte: 41.4" "Group enriched" "Detected in many" 15 "granulocytes: 13.0;monocytes: 41.4" "Cancer enriched" "Detected in single" 5 "colorectal cancer: 2.4" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "unprognostic (4.30e-2)" "unprognostic (8.86e-2)" "unprognostic (1.07e-1)" "unprognostic (4.74e-2)" "unprognostic (1.66e-1)" "unprognostic (5.22e-2)" "unprognostic (9.90e-2)" "unprognostic (8.29e-3)" "unprognostic (1.47e-1)" "unprognostic (4.38e-3)" "unprognostic (7.39e-3)" "unprognostic (3.25e-1)" "unprognostic (1.82e-9)" "unprognostic (7.30e-2)" "unprognostic (2.67e-3)" "unprognostic (1.87e-1)" "unprognostic (1.50e-1)" CLDN15 ENSG00000106404 "Claudin 15" P56746 7 101232092-101238820 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "adipose tissue: 63.3;intestine: 252.3" "Cell type enhanced" "Detected in many" "Mesothelial cells: 195.7;Proximal enterocytes: 570.9;Undifferentiated cells: 124.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (8.85e-2)" "unprognostic (1.48e-1)" "unprognostic (4.93e-2)" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (1.03e-1)" "unprognostic (6.56e-2)" "unprognostic (1.79e-1)" "prognostic favorable (2.56e-4)" "unprognostic (2.02e-2)" "prognostic unfavorable (5.31e-5)" "unprognostic (9.98e-2)" "unprognostic (2.89e-2)" "unprognostic (9.64e-2)" "prognostic favorable (3.30e-4)" HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 111.4" "Cell type enhanced" "Detected in some" "Astrocytes: 37.8;Distal enterocytes: 51.0;Enteroendocrine cells: 27.2;Intestinal goblet cells: 37.6;Oligodendrocyte precursor cells: 24.5;Paneth cells: 48.0;Proximal enterocytes: 135.8;Undifferentiated cells: 29.0" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.5;liver cancer: 2.8;pancreatic cancer: 4.0;renal cancer: 4.6;stomach cancer: 10.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Small intestine - Absorption" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: AB_1850822, HPA010610: AB_2668318" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (9.44e-2)" "unprognostic (5.60e-2)" "unprognostic (4.65e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.92e-1)" "unprognostic (8.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.83e-2)" "unprognostic (6.93e-3)" "unprognostic (1.67e-2)" "unprognostic (2.11e-1)" "unprognostic (4.22e-2)" "unprognostic (2.47e-2)" LRRC19 FLJ21302 ENSG00000184434 "Leucine rich repeat containing 19" Q9H756 9 26993136-27005672 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 35.0;kidney: 41.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.3;Distal enterocytes: 127.7;Enteroendocrine cells: 20.1;Intestinal goblet cells: 21.9;Paneth cells: 29.3;Proximal enterocytes: 69.2;Proximal tubular cells: 52.0" "Group enriched" "Detected in some" 5 "colorectal cancer: 6.0;renal cancer: 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "colorectal cancer: 1.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 190000 "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "unprognostic (2.27e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (6.30e-2)" "unprognostic (5.20e-2)" "unprognostic (2.30e-1)" "unprognostic (4.05e-2)" "unprognostic (1.85e-2)" "unprognostic (4.16e-2)" "unprognostic (9.21e-5)" "unprognostic (1.87e-2)" "unprognostic (4.48e-2)" "prognostic favorable (7.08e-8)" "unprognostic (2.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (3.32e-2)" MLXIPL "bHLHd14, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH" ENSG00000009950 "MLX interacting protein like" Q9NP71 7 73593194-73624543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 595.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 89.7;Enteroendocrine cells: 82.4;Hepatocytes: 198.8;Kupffer cells: 56.4;Proximal enterocytes: 92.5;Skeletal myocytes: 48.8" "Cancer enriched" "Detected in many" 6 "liver cancer: 60.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064640 Supported Nucleoplasm "Intracellular and membrane" Transcription NA NA "Cluster 83: Liver - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Hepatocytes - Metabolism" Nucleoplasm "HPA064640: AB_2685309" "unprognostic (1.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-2)" "unprognostic (4.86e-2)" "unprognostic (5.04e-1)" "unprognostic (1.06e-3)" "unprognostic (3.46e-3)" "unprognostic (9.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (6.13e-3)" "unprognostic (4.91e-2)" "unprognostic (2.25e-2)" "unprognostic (1.12e-1)" "unprognostic (3.46e-2)" "unprognostic (2.46e-2)" "unprognostic (7.72e-3)" NAGS "AGAS, ARGA, NAT7" ENSG00000161653 "N-acetylglutamate synthase" Q8N159 17 44004622-44009068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Urea cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 15.4;liver: 47.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 17.5;Proximal enterocytes: 44.8;Proximal tubular cells: 16.8;Spermatocytes: 13.8" "Cancer enhanced" "Detected in all" "liver cancer: 12.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA027300 Supported Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 83: Liver - Metabolism" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "HPA027300: AB_2672207" "unprognostic (1.51e-3)" "unprognostic (9.24e-2)" "unprognostic (1.68e-1)" "unprognostic (8.67e-2)" "unprognostic (1.44e-2)" "unprognostic (1.30e-3)" "unprognostic (2.38e-2)" "unprognostic (1.98e-1)" "unprognostic (3.14e-2)" "unprognostic (2.73e-2)" "unprognostic (2.53e-3)" "unprognostic (1.46e-1)" "unprognostic (5.19e-2)" "unprognostic (6.99e-2)" "unprognostic (1.29e-2)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" PDZD3 "FLJ22756, IKEPP, NHERF4, PDZK2" ENSG00000172367 "PDZ domain containing 3" Q86UT5 11 119185457-119190223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 18.8;kidney: 16.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 71.8;Gastric mucus-secreting cells: 27.1;Paneth cells: 29.9;Proximal enterocytes: 66.4;Proximal tubular cells: 26.5;Undifferentiated cells: 15.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.3;renal cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" HPA077887 Enhanced NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 4 "HPA077887: " "unprognostic (2.42e-2)" "unprognostic (1.51e-1)" "unprognostic (2.65e-1)" "unprognostic (5.51e-2)" "unprognostic (1.59e-1)" "unprognostic (5.39e-2)" "unprognostic (6.07e-2)" "unprognostic (3.22e-1)" "unprognostic (1.86e-2)" "unprognostic (6.58e-3)" "unprognostic (9.00e-2)" "unprognostic (6.08e-2)" "unprognostic (8.72e-2)" "unprognostic (1.08e-1)" "unprognostic (3.37e-1)" "unprognostic (1.38e-1)" "unprognostic (3.41e-3)" PLS1 ENSG00000120756 "Plastin 1" Q14651 3 142596393-142713664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 306.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 375.1;Intestinal goblet cells: 159.1;Paneth cells: 132.8;Proximal enterocytes: 319.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 36.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 2.6;NK-cells: 3.0;T-cells: 2.5" "Low cancer specificity" "Detected in all" "Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000895, HPA055744, HPA061936" Enhanced Approved "Plasma membrane" NA NA 56000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Small intestine - Absorption" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" "HPA000895: , HPA055744: AB_2682903, HPA061936: " "unprognostic (1.29e-1)" "unprognostic (2.61e-1)" "unprognostic (3.15e-3)" "unprognostic (2.22e-2)" "unprognostic (1.20e-1)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.33e-1)" "unprognostic (7.78e-2)" "prognostic unfavorable (4.84e-4)" "unprognostic (3.14e-2)" "prognostic favorable (8.76e-6)" "unprognostic (1.99e-2)" "unprognostic (8.64e-2)" "unprognostic (7.22e-2)" "unprognostic (3.82e-2)" PPP1R14D "CPI17-like, FLJ20251, GBPI-1, MGC119014, MGC119016" ENSG00000166143 "Protein phosphatase 1 regulatory inhibitor subunit 14D" Q9NXH3 15 40815451-40828709 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 107.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 309.5;Enteroendocrine cells: 97.4;Paneth cells: 190.3;Proximal enterocytes: 432.6;Undifferentiated cells: 70.8" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 45.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "colorectal cancer: 30.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA041846 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "HPA041846: AB_10794307" "unprognostic (1.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (5.91e-3)" "unprognostic (1.17e-2)" "unprognostic (4.68e-2)" "unprognostic (1.89e-1)" "unprognostic (7.74e-2)" "unprognostic (2.86e-1)" "unprognostic (5.26e-3)" "unprognostic (3.16e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.55e-1)" "unprognostic (1.43e-2)" "unprognostic (3.74e-3)" "unprognostic (3.11e-2)" SLC35G1 "C10orf60, FLJ33990, TMEM20" ENSG00000176273 "Solute carrier family 35 member G1" Q2M3R5 10 93893973-93956062 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 66.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 26.4;Peritubular cells: 35.0;Proximal enterocytes: 42.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 25: Small intestine - Absorption" "Cluster 44: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 4 "unprognostic (1.94e-2)" "unprognostic (1.90e-1)" "unprognostic (9.48e-2)" "unprognostic (1.65e-1)" "unprognostic (7.90e-4)" "unprognostic (8.89e-2)" "unprognostic (9.01e-3)" "unprognostic (1.15e-2)" "unprognostic (9.47e-2)" "unprognostic (7.90e-2)" "unprognostic (2.09e-1)" "unprognostic (4.30e-2)" "unprognostic (1.65e-2)" "unprognostic (2.29e-3)" "unprognostic (3.28e-1)" "unprognostic (3.02e-1)" "unprognostic (2.30e-1)" UGT2A3 FLJ21934 ENSG00000135220 "UDP glucuronosyltransferase family 2 member A3" Q6UWM9 4 68928463-68951804 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 30.5;kidney: 20.4;liver: 12.9;pancreas: 15.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 89.7;Distal enterocytes: 104.0;Enteroendocrine cells: 45.6;Hepatocytes: 51.0;Paneth cells: 57.8;Proximal enterocytes: 229.6;Proximal tubular cells: 113.3;Undifferentiated cells: 81.4" "Cancer enriched" "Detected in many" 5 "renal cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045108 Supported NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" "HPA045108: AB_2679218" "prognostic favorable (3.31e-4)" "unprognostic (3.97e-3)" "unprognostic (8.87e-3)" "prognostic favorable (6.07e-7)" "unprognostic (2.10e-2)" UPK3A UPK3 ENSG00000100373 "Uroplakin 3A" O75631 22 45284949-45295874 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "prostate: 20.6;skeletal muscle: 33.8;urinary bladder: 46.4" "Cell type enhanced" "Detected in some" "Club cells: 38.4;dendritic cells: 12.1;Prostatic glandular cells: 61.7;Proximal enterocytes: 27.5;Schwann cells: 15.5" "Group enriched" "Detected in many" 6 "prostate cancer: 35.3;urothelial cancer: 78.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "myeloid DC: 86.7" "Group enriched" "Detected in many" 16 "dendritic cells: 86.7;monocytes: 32.2" "Cancer enhanced" "Detected in some" "breast cancer: 7.8;colorectal cancer: 7.4;prostate cancer: 6.3" "Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018407, HPA018415" Enhanced Uncertain "Nuclear membrane,Nuclear bodies" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 2 "Nuclear membrane" "Nuclear bodies" "HPA018407: AB_1858641, HPA018415: AB_1858640" "unprognostic (1.27e-2)" "unprognostic (3.20e-3)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "unprognostic (9.42e-2)" "unprognostic (3.98e-5)" "unprognostic (1.69e-2)" "unprognostic (4.82e-4)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-5)" "unprognostic (2.01e-2)" "unprognostic (5.45e-2)" "unprognostic (1.83e-1)" "unprognostic (6.05e-3)" VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132680849-132714055 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "gallbladder: 86.2;intestine: 132.5;liver: 212.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 55.3;Ductal cells: 259.1;Exocrine glandular cells: 71.0;Hepatocytes: 67.5;monocytes: 181.9;Proximal enterocytes: 52.0" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 13.7;non-classical monocyte: 12.0" "Group enriched" "Detected in many" 80 "dendritic cells: 5.0;granulocytes: 8.5;monocytes: 13.7" "Cancer enhanced" "Detected in many" "liver cancer: 13.2;thyroid cancer: 9.6" "Adipose subcutaneous - Macrophages, Colon - Macrophages, Kidney - Proximal tubular cells, Lung - Neutrophil_2" "Region enhanced" "Detected in single" "white matter: 2.4" "Not detected" "Not detected" "HPA046103, HPA064145" Approved Approved Vesicles "Intracellular and membrane" Enzyme NA NA 980000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Non-specific - Mixed function" Vesicles "HPA046103: , HPA064145: AB_2685197" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" A1CF "ACF, ACF64, ACF65, APOBEC1CF, ASP" ENSG00000148584 "APOBEC1 complementation factor" Q9NQ94 10 50799409-50885675 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 148.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 152.6;Distal enterocytes: 91.2;Enteroendocrine cells: 92.5;Hepatocytes: 340.5;Intestinal goblet cells: 59.4;Paneth cells: 90.4;Proximal enterocytes: 148.7;Proximal tubular cells: 91.8" "Cancer enriched" "Detected in some" 6 "liver cancer: 18.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "liver cancer: 21.2" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA037779, HPA044079" Enhanced Supported Nucleoplasm NA NA "Cluster 83: Liver - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 16 Nucleoplasm "HPA037779: AB_10670529, HPA044079: AB_2678800" "unprognostic (3.87e-3)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.21e-3)" "unprognostic (2.73e-1)" "unprognostic (4.61e-3)" "unprognostic (1.71e-1)" "unprognostic (7.38e-3)" "unprognostic (1.30e-2)" "unprognostic (2.46e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-3)" "unprognostic (1.97e-2)" "unprognostic (2.77e-1)" "unprognostic (2.19e-2)" "unprognostic (8.50e-4)" ASL ASAL ENSG00000126522 "Argininosuccinate lyase" P04424 7 66075800-66094697 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 386.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 335.9;Hepatocytes: 508.0;Proximal enterocytes: 267.7;Proximal tubular cells: 221.3" "Cancer enhanced" "Detected in all" "liver cancer: 52.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003696, HPA016646" Enhanced Approved Cytosol NA NA 12000000 "Cluster 25: Non-specific - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 2 Cytosol "CAB003696: AB_425316, HPA016646: AB_1845096" "unprognostic (2.95e-2)" "prognostic unfavorable (4.05e-6)" "unprognostic (4.83e-1)" "unprognostic (4.18e-3)" "unprognostic (3.52e-2)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (2.07e-1)" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (7.25e-2)" "unprognostic (4.95e-2)" "unprognostic (2.07e-2)" "unprognostic (3.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-1)" "unprognostic (8.40e-3)" ASS1 "ASS, CTLN1" ENSG00000130707 "Argininosuccinate synthase 1" P00966 9 130444961-130501274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 1238.9;liver: 1978.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 1030.8;Proximal enterocytes: 610.9;Proximal tubular cells: 1113.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020896, HPA020934" Enhanced Supported Nucleoplasm,Cytosol No No 6400000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 2 Cytosol Nucleoplasm "HPA020896: AB_1845117, HPA020934: AB_1845118" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (8.14e-9)" "unprognostic (3.06e-1)" "unprognostic (1.05e-2)" "unprognostic (2.93e-2)" "unprognostic (3.71e-2)" "unprognostic (3.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.02e-2)" "unprognostic (4.24e-2)" "unprognostic (2.92e-3)" "unprognostic (1.41e-2)" "unprognostic (1.05e-1)" "unprognostic (3.14e-1)" "unprognostic (4.72e-3)" BNIP5 "C6orf222, DKFZp779B1540" ENSG00000189325 "BCL2 interacting protein 5" P0C671 6 36315761-36336888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 24.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 127.0;Enteroendocrine cells: 47.8;Exocrine glandular cells: 76.6;Intestinal goblet cells: 93.6;Paneth cells: 67.9;Proximal enterocytes: 83.1" "Group enriched" "Detected in some" 19 "colorectal cancer: 8.7;pancreatic cancer: 5.1;stomach cancer: 8.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.4" "Colon - Colon enterocytes, Pancreas - Ductal cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA038407, HPA058189" Uncertain Approved Cytosol NA NA "Cluster 25: Small intestine - Absorption" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 5 Cytosol "HPA038407: AB_10669644, HPA058189: AB_2683634" "unprognostic (1.97e-5)" "unprognostic (5.46e-3)" "unprognostic (3.93e-1)" "unprognostic (1.49e-1)" "unprognostic (7.52e-2)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (4.13e-1)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (6.75e-2)" "unprognostic (3.04e-2)" "unprognostic (4.55e-2)" "unprognostic (3.16e-2)" "unprognostic (3.98e-1)" "unprognostic (1.66e-4)" BRSK1 "KIAA1811, SAD-B" ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312562 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 197.5;pituitary gland: 51.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.4;Excitatory neurons: 29.1;Horizontal cells: 35.3;Inhibitory neurons: 26.4;Oligodendrocyte precursor cells: 16.0;Oligodendrocytes: 27.3;Plasma cells: 14.8;Proximal enterocytes: 21.1" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 43.9" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Nucleoplasm "Cell Junctions" "HPA021212: AB_1845455, HPA061719: AB_2684593" "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" CCL15 "HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3" ENSG00000275718 "C-C motif chemokine ligand 15" Q16663 17 35996440-36001553 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 80.2;liver: 30.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 248.6;Enteroendocrine cells: 98.2;Intestinal goblet cells: 170.4;Paneth cells: 297.1;Proximal enterocytes: 484.4;Undifferentiated cells: 104.6" "Cancer enhanced" "Detected in many" "liver cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "colorectal cancer: 24.6;Gastric cancer: 10.9;liver cancer: 14.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells" HPA058608 Approved "Golgi apparatus,Vesicles" "Secreted to blood" Chemokine NA NA 3270000 11000000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Golgi apparatus" Vesicles "HPA058608: AB_2683776" "unprognostic (1.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-2)" "unprognostic (1.40e-1)" "unprognostic (8.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" "unprognostic (2.41e-2)" "unprognostic (1.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.15e-1)" "unprognostic (1.07e-2)" "prognostic favorable (3.02e-4)" EFNA2 "ELF-1, EPLG6, LERK6" ENSG00000099617 "Ephrin A2" O43921 19 1285873-1301431 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "gallbladder: 3.4;intestine: 12.0;liver: 12.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 21.0;Distal enterocytes: 56.7;Intestinal goblet cells: 18.0;Paneth cells: 32.4;Proximal enterocytes: 56.4;Undifferentiated cells: 19.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.5;stomach cancer: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.0" "Colon - Colon enterocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067567 Approved Mitochondria,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 5: Enterocytes - Absorption" 1 "Mitochondria, Cytosol" "HPA067567: AB_2732771" "unprognostic (1.98e-1)" "unprognostic (3.26e-1)" "unprognostic (2.87e-3)" "unprognostic (1.96e-2)" "unprognostic (4.04e-2)" "unprognostic (3.90e-1)" "unprognostic (7.19e-2)" "unprognostic (2.34e-3)" "unprognostic (3.58e-2)" "unprognostic (6.82e-2)" "unprognostic (8.48e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-3)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (2.82e-4)" "unprognostic (1.94e-1)" EXOC3L4 C14orf73 ENSG00000205436 "Exocyst complex component 3 like 4" Q17RC7 14 103094725-103110559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 17.6;liver: 40.1" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 18.3;Hepatocytes: 18.5;Proximal enterocytes: 32.8;Proximal tubular cells: 11.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA043661 Approved NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" "HPA043661: AB_10965693" "unprognostic (8.71e-2)" "unprognostic (7.42e-3)" "prognostic unfavorable (1.43e-5)" "unprognostic (8.20e-2)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (9.53e-3)" "unprognostic (6.64e-2)" "unprognostic (1.49e-1)" "unprognostic (6.98e-2)" "unprognostic (3.12e-1)" "unprognostic (8.96e-2)" "unprognostic (2.22e-1)" "unprognostic (1.32e-2)" "unprognostic (5.21e-2)" "unprognostic (2.22e-1)" "unprognostic (2.81e-4)" FMO4 FMO2 ENSG00000076258 "Flavin containing dimethylaniline monoxygenase 4" P31512 1 171314183-171342084 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 46.8;liver: 59.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 22.5;Oligodendrocytes: 17.2;Proximal enterocytes: 15.9;Proximal tubular cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA049100, HPA072438" Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Vesicles, Cytosol" "HPA049100: AB_2680629, HPA072438: " "unprognostic (1.83e-2)" "unprognostic (1.17e-1)" "unprognostic (6.18e-2)" "unprognostic (3.01e-2)" "unprognostic (8.27e-2)" "unprognostic (4.13e-1)" "prognostic favorable (1.09e-4)" "prognostic favorable (7.45e-4)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (5.99e-2)" "unprognostic (2.90e-1)" "prognostic favorable (6.96e-4)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (7.45e-3)" "unprognostic (1.95e-1)" FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 662.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 94.5;Cholangiocytes: 122.1;Hepatocytes: 245.3;Intestinal goblet cells: 58.4;Proximal enterocytes: 93.4;Proximal tubular cells: 61.7" "Cancer enriched" "Detected in many" 7 "liver cancer: 43.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "liver cancer: 9.0" "Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "Endoplasmic reticulum, Cytosol" "HPA012373: AB_1848975" "unprognostic (2.70e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (2.43e-2)" "unprognostic (2.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-2)" "unprognostic (2.93e-1)" "unprognostic (1.13e-1)" "prognostic favorable (1.34e-6)" "unprognostic (3.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.85e-1)" "unprognostic (4.11e-2)" OXER1 "GPCR, GPR170, TG1019" ENSG00000162881 "Oxoeicosanoid receptor 1" Q8TDS5 2 42762499-42764135 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 55.0" "Cell type enhanced" "Detected in some" "Hepatocytes: 6.4;Melanocytes: 5.2;Paneth cells: 5.2;Proximal enterocytes: 13.9" "Cancer enhanced" "Detected in all" "liver cancer: 12.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 73.5;eosinophil: 158.2" "Lineage enriched" "Detected in many" 81 "granulocytes: 158.2" "Cancer enhanced" "Detected in some" "liver cancer: 2.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" HPA051433 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 29 "HPA051433: AB_2681485" "unprognostic (6.77e-2)" "unprognostic (4.20e-2)" "unprognostic (3.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.09e-3)" "unprognostic (4.45e-3)" "unprognostic (7.80e-2)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-3)" "unprognostic (5.39e-2)" "unprognostic (1.82e-3)" "unprognostic (5.83e-2)" "unprognostic (1.66e-1)" "unprognostic (4.89e-2)" "unprognostic (5.46e-2)" PCK2 "PEPCK, PEPCK2" ENSG00000100889 "Phosphoenolpyruvate carboxykinase 2, mitochondrial" Q16822 14 24094053-24110598 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "intestine: 190.6;kidney: 95.5;liver: 365.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 307.6;Proximal enterocytes: 765.9;Proximal tubular cells: 138.6" "Cancer enhanced" "Detected in all" "liver cancer: 91.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB018734, HPA051162, HPA053502" Enhanced Enhanced Mitochondria NA NA 3500000 "Cluster 14: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 22: Proximal enterocytes - Digestion" 2 Mitochondria "CAB018734: AB_2160168, HPA051162: AB_2681368, HPA053502: AB_2682171" "unprognostic (3.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.07e-1)" "unprognostic (3.11e-1)" "unprognostic (2.10e-1)" "prognostic favorable (2.81e-4)" "unprognostic (3.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.33e-2)" "unprognostic (2.81e-1)" "unprognostic (3.71e-1)" "unprognostic (2.82e-2)" "unprognostic (1.17e-1)" PDZD7 "bA108L7.8, DFNB57, FLJ23209, PDZK7" ENSG00000186862 "PDZ domain containing 7" Q9H5P4 10 101007679-101032295 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 17.3;intestine: 19.4;pituitary gland: 5.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.4;Excitatory neurons: 31.2;Horizontal cells: 25.2;Inhibitory neurons: 15.8;Proximal enterocytes: 60.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074542 Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" 1 Nucleoplasm "HPA074542: " "unprognostic (1.46e-1)" "unprognostic (2.85e-3)" "unprognostic (3.96e-2)" "unprognostic (2.10e-1)" "unprognostic (2.15e-2)" "unprognostic (2.83e-2)" "unprognostic (1.38e-2)" "unprognostic (5.31e-2)" "unprognostic (2.52e-2)" "unprognostic (2.95e-2)" "unprognostic (2.45e-1)" "unprognostic (1.87e-3)" "unprognostic (3.54e-3)" "unprognostic (3.89e-1)" "unprognostic (1.79e-1)" "unprognostic (3.51e-2)" "unprognostic (2.80e-1)" SLC30A10 "DKFZp547M236, ZnT-10, ZNT8, ZRC1" ENSG00000196660 "Solute carrier family 30 member 10" Q6XR72 1 219685427-219959018 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 23.8;liver: 33.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.5;Early spermatids: 52.3;Hepatocytes: 128.4;Late spermatids: 38.6;Proximal enterocytes: 43.3" "Cancer enriched" "Detected in some" 14 "liver cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.6" "Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064547 Enhanced NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 3 "HPA064547: AB_2732715" "unprognostic (7.88e-2)" "unprognostic (1.07e-2)" "unprognostic (1.02e-1)" "unprognostic (7.25e-2)" "unprognostic (1.75e-2)" "unprognostic (3.74e-3)" "unprognostic (6.96e-2)" "unprognostic (3.72e-2)" "unprognostic (1.41e-1)" "unprognostic (1.95e-2)" "unprognostic (5.10e-2)" "unprognostic (3.10e-3)" "unprognostic (4.47e-7)" "unprognostic (3.16e-1)" "unprognostic (6.11e-2)" "unprognostic (6.19e-3)" "unprognostic (5.72e-2)" SULT1A3 "STM, TL-PST" ENSG00000261052 "Sulfotransferase family 1A member 3" P0DMM9 16 30199228-30204310 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 232.9" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 22.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 64.6;intermediate monocyte: 55.7;myeloid DC: 35.2;non-classical monocyte: 26.8" "Group enriched" "Detected in all" 11 "dendritic cells: 35.2;monocytes: 64.6" "Low cancer specificity" "Detected in all" "HPA049500, HPA051051" Supported NA NA 160000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Small intestine - Absorption" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 3 "HPA049500: AB_2680796, HPA051051: AB_2681327" "unprognostic (2.61e-1)" "unprognostic (1.72e-3)" "unprognostic (1.98e-3)" "unprognostic (4.98e-2)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (7.27e-2)" "unprognostic (2.09e-2)" "unprognostic (2.99e-2)" "unprognostic (2.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.18e-8)" "unprognostic (2.34e-2)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (9.48e-5)" TRIM15 "RNF93, ZNF178, ZNFB7" ENSG00000204610 "Tripartite motif containing 15" Q9C019 6 30163206-30172693 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 16.6;kidney: 5.9;liver: 14.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 93.7;Intestinal goblet cells: 27.7;Paneth cells: 93.7;Proximal enterocytes: 81.2;Proximal tubular cells: 19.6" "Group enriched" "Detected in many" 4 "colorectal cancer: 14.4;liver cancer: 5.6;pancreatic cancer: 7.7;renal cancer: 4.4;stomach cancer: 8.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.8;colorectal cancer: 5.2;Gastric cancer: 6.5" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA047527 Approved "Centriolar satellite,Cytosol" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 7 Cytosol "Centriolar satellite" "HPA047527: " "unprognostic (2.61e-1)" "unprognostic (1.54e-1)" "unprognostic (1.85e-1)" "unprognostic (1.71e-1)" "unprognostic (5.36e-2)" "unprognostic (1.92e-2)" "unprognostic (7.57e-4)" "unprognostic (5.27e-2)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (2.16e-2)" "unprognostic (2.19e-2)" "unprognostic (3.83e-1)" "unprognostic (1.63e-1)" "unprognostic (2.41e-1)" ZC3H12D "C6orf95, dJ281H8.1, MCPIP4" ENSG00000178199 "Zinc finger CCCH-type containing 12D" A2A288 6 149446795-149485014 "Disease related genes, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 3.5;intestine: 4.6;lymphoid tissue: 12.3" "Cell type enhanced" "Detected in some" "B-cells: 15.5;dendritic cells: 7.9;Kupffer cells: 8.7;Macrophages: 8.3;monocytes: 8.0;Proximal enterocytes: 7.4;T-cells: 19.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Leukemia: 4.2;lymphoma: 11.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036897 Uncertain Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Nucleoplasm, Cytoplasmic bodies" "HPA036897: AB_10672104" "unprognostic (2.89e-2)" "unprognostic (3.91e-4)" "unprognostic (1.68e-2)" "unprognostic (1.88e-2)" "unprognostic (3.12e-1)" "unprognostic (2.47e-6)" "unprognostic (2.20e-2)" "unprognostic (2.50e-3)" "unprognostic (1.34e-1)" "unprognostic (3.30e-2)" "unprognostic (2.33e-2)" "unprognostic (1.86e-1)" "unprognostic (1.28e-4)" "unprognostic (1.21e-2)" "unprognostic (9.24e-3)" "unprognostic (6.99e-2)" "unprognostic (5.52e-2)" BAIAP2L2 "FLJ22582, pinkbar" ENSG00000128298 "BAR/IMD domain containing adaptor protein 2 like 2" Q6UXY1 22 38084652-38111015 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 95.9;kidney: 41.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 64.9;Enteroendocrine cells: 30.3;Intestinal goblet cells: 52.7;Oligodendrocytes: 28.9;Proximal enterocytes: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 53.7" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Region enhanced" "Detected in many" "olfactory bulb: 3.7" "Low region specificity" "Detected in many" HPA003043 Approved NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" "HPA003043: AB_2227864" "unprognostic (2.15e-1)" "unprognostic (4.23e-2)" "unprognostic (9.82e-2)" "unprognostic (5.91e-2)" "unprognostic (7.75e-2)" "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (1.37e-3)" "unprognostic (2.30e-2)" "unprognostic (2.14e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-3)" "unprognostic (1.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.27e-1)" "unprognostic (4.23e-2)" "unprognostic (4.51e-2)" BDH1 "BDH, SDR9C1" ENSG00000161267 "3-hydroxybutyrate dehydrogenase 1" Q02338 3 197509783-197573323 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 313.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 96.6;Hepatocytes: 115.2;Proximal enterocytes: 83.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030947, HPA058709" Enhanced Approved Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" Mitochondria "HPA030947: AB_10669548, HPA058709: AB_2683797" "unprognostic (2.72e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.13e-1)" "unprognostic (3.93e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.86e-7)" "unprognostic (2.08e-1)" "unprognostic (3.85e-2)" "unprognostic (4.53e-2)" "unprognostic (5.17e-3)" "unprognostic (5.85e-3)" "prognostic favorable (7.12e-8)" "unprognostic (5.62e-2)" "unprognostic (1.74e-1)" "unprognostic (6.22e-2)" "unprognostic (1.02e-1)" BST1 "BST-1, cADPR2, CD157" ENSG00000109743 "Bone marrow stromal cell antigen 1" Q10588 4 15703065-15738313 "CD markers, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 138.1;intestine: 47.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 61.4;Kupffer cells: 31.0;Proximal enterocytes: 79.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 258.3;neutrophil: 294.2" "Group enriched" "Detected in many" 94 "dendritic cells: 79.0;granulocytes: 294.2;monocytes: 258.3" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050121 Uncertain "Intracellular and membrane" Enzyme NA NA 190000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 29: Monocytes - Innate immune response" "HPA050121: AB_2681025" "unprognostic (2.95e-1)" "unprognostic (3.61e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-2)" "unprognostic (7.49e-2)" "unprognostic (2.89e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (1.08e-1)" "unprognostic (4.06e-2)" "unprognostic (4.83e-3)" "unprognostic (1.94e-3)" "unprognostic (3.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.95e-1)" C15orf48 "COXFA4L3, MIR147BHG, MISTRAV, MOCCI, NMES1" ENSG00000166920 "Chromosome 15 open reading frame 48" Q9C002 15 45430579-45448761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 893.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4361.0;Enteroendocrine cells: 1468.6;Exocrine glandular cells: 2025.4;Intestinal goblet cells: 1372.4;Langerhans cells: 2561.4;Paneth cells: 2158.2;Proximal enterocytes: 3050.5;Undifferentiated cells: 1467.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 6.3" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;intermediate monocyte: 1.6;myeloid DC: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 606.0" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA012943 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 1 "HPA012943: AB_2668774" "unprognostic (5.29e-3)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (7.83e-2)" "unprognostic (1.17e-1)" "unprognostic (9.74e-3)" "unprognostic (1.48e-3)" "unprognostic (1.28e-3)" "unprognostic (1.59e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-3)" "unprognostic (5.95e-2)" "unprognostic (8.86e-2)" "unprognostic (2.37e-1)" "unprognostic (6.51e-2)" "unprognostic (1.39e-1)" "unprognostic (3.66e-1)" CDHR5 "FLJ20219, MU-PCDH, MUCDHL, MUPCDH" ENSG00000099834 "Cadherin related family member 5" Q9HBB8 11 616577-626078 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 288.9;liver: 126.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 655.8;Intestinal goblet cells: 201.7;Paneth cells: 440.9;Proximal enterocytes: 2282.1" "Cancer enhanced" "Detected in many" "liver cancer: 61.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.7" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009081, HPA009173, CAB025004" Enhanced "Intracellular and membrane" Other NA NA 190000000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "CAB025004: , HPA009081: AB_1079428, HPA009173: AB_1079429" "unprognostic (7.65e-2)" "unprognostic (1.42e-1)" "unprognostic (9.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.05e-1)" "unprognostic (5.56e-3)" "unprognostic (4.89e-2)" "unprognostic (3.85e-2)" "unprognostic (5.75e-2)" "unprognostic (6.36e-2)" "unprognostic (7.95e-2)" "unprognostic (5.07e-2)" "unprognostic (5.01e-2)" "unprognostic (3.90e-1)" "unprognostic (8.85e-2)" "unprognostic (2.29e-1)" "unprognostic (2.14e-2)" CLRN3 "MGC32871, TMEM12, USH3AL1" ENSG00000180745 "Clarin 3" Q8NCR9 10 127877841-127892941 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 86.6;kidney: 42.3;liver: 77.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 95.1;Enteroendocrine cells: 53.4;Hepatocytes: 40.4;Intestinal goblet cells: 81.5;Paneth cells: 77.2;Proximal enterocytes: 153.7;Proximal tubular cells: 55.2;Undifferentiated cells: 34.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.3;renal cancer: 30.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "colorectal cancer: 37.8;Gastric cancer: 20.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014482 Approved NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "HPA014482: AB_2082885" "unprognostic (7.34e-3)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (1.46e-3)" "unprognostic (1.22e-2)" "unprognostic (1.06e-1)" "unprognostic (5.08e-2)" "unprognostic (2.62e-1)" "unprognostic (6.22e-2)" "unprognostic (4.67e-1)" "unprognostic (8.86e-2)" "prognostic favorable (8.98e-4)" "unprognostic (1.74e-1)" "unprognostic (2.89e-3)" "unprognostic (3.00e-2)" CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 199.0;liver: 576.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 363.4;Hofbauer cells: 147.0;Proximal enterocytes: 194.6" "Group enriched" "Detected in all" 4 "liver cancer: 176.9;melanoma: 85.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.6;neutrophil: 126.9" "Group enriched" "Detected in many" 21 "granulocytes: 126.9;monocytes: 151.6" "Cancer enhanced" "Detected in many" "liver cancer: 29.9;skin cancer: 65.6" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" Mitochondria Cytosol "HPA059155: AB_2683933" "prognostic favorable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favorable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" DECR2 "PDCR, SDR17C1" ENSG00000242612 "2,4-dienoyl-CoA reductase 2" Q9NUI1 16 401858-412487 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 161.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 133.2;Proximal enterocytes: 76.8;Proximal tubular cells: 156.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047631 Approved Peroxisomes,Microtubules NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 83: Liver - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 4 Peroxisomes Microtubules "HPA047631: " "unprognostic (2.74e-2)" "unprognostic (3.84e-1)" "unprognostic (1.83e-1)" "unprognostic (4.44e-3)" "unprognostic (1.77e-1)" "unprognostic (7.45e-2)" "unprognostic (2.38e-2)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (3.02e-2)" "unprognostic (3.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.12e-1)" "unprognostic (3.40e-1)" "unprognostic (2.21e-1)" "unprognostic (1.94e-1)" "unprognostic (4.22e-3)" DQX1 FLJ23757 ENSG00000144045 "DEAQ-box RNA dependent ATPase 1" Q8TE96 2 74518131-74526281 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 15.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 20.0;Gastric mucus-secreting cells: 15.9;Intestinal goblet cells: 16.2;Paneth cells: 19.0;Proximal enterocytes: 41.4;Undifferentiated cells: 8.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.5" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA039158, HPA046763" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoli fibrillar center" "HPA039158: AB_10960125, HPA046763: " "unprognostic (2.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (9.95e-2)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-1)" "unprognostic (4.54e-2)" "unprognostic (1.68e-1)" "unprognostic (7.67e-2)" "unprognostic (2.21e-2)" "unprognostic (0.00e+0)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-3)" ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 15.3;intestine: 16.7;lymphoid tissue: 56.1;skin 1: 25.8;testis: 16.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.2;Gastric mucus-secreting cells: 4.1;Proximal enterocytes: 5.5;Squamous epithelial cells: 19.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 8 "choroid plexus: 11.0" "Group enriched" "Detected in some" 4 "memory B-cell: 11.2;naive B-cell: 17.0" "Lineage enriched" "Detected in many" 5 "B-cells: 17.0" "Cancer enriched" "Detected in many" 5 "lymphoma: 72.9" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 36: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 49: Non-specific - Transcription" 1 "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: AB_10795352, HPA073494: " "unprognostic (2.59e-2)" "unprognostic (4.41e-1)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-3)" "unprognostic (1.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.19e-1)" "unprognostic (3.53e-1)" "unprognostic (1.87e-1)" "unprognostic (3.67e-2)" "unprognostic (8.95e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-2)" ENSG00000284797 ENSG00000284797 "Novel protein" 19 18249950-18255419 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "intestine: 3.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 274.5;Enteroendocrine cells: 46.5;Paneth cells: 201.7;Proximal enterocytes: 71.0;Undifferentiated cells: 48.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Esophageal cancer: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" FAM3D "EF7, OIT1" ENSG00000198643 "FAM3 metabolism regulating signaling molecule D" Q96BQ1 3 58633946-58666834 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 257.4;intestine: 472.8;salivary gland: 454.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 358.6;Distal enterocytes: 916.6;Enteroendocrine cells: 310.4;Intestinal goblet cells: 1087.5;Ionocytes: 340.2;Paneth cells: 568.5;Proximal enterocytes: 348.8;Serous glandular cells: 586.3;Undifferentiated cells: 430.5" "Cancer enriched" "Detected in many" 4 "colorectal cancer: 151.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 3.7" "Lineage enhanced" "Detected in single" "granulocytes: 3.7" "Group enriched" "Detected in some" 6 "colorectal cancer: 29.2;Gastric cancer: 13.6" "Colon - Colon enterocytes, Pancreas - Ductal cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013844 Approved "Secreted to digestive system" "No annotated function" NA NA 15000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA013844: AB_2668897" "prognostic favorable (7.51e-4)" "unprognostic (1.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.67e-2)" "unprognostic (5.51e-2)" "prognostic favorable (1.89e-4)" "unprognostic (7.97e-2)" "unprognostic (6.54e-2)" "unprognostic (7.43e-2)" "unprognostic (5.48e-2)" "unprognostic (2.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.68e-2)" "unprognostic (1.64e-1)" "unprognostic (2.00e-1)" "unprognostic (6.97e-4)" "unprognostic (2.34e-2)" GCHFR "GFRP, HsT16933" ENSG00000137880 "GTP cyclohydrolase I feedback regulator" P30047 15 40764068-40767708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 341.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 848.9;Hofbauer cells: 483.5;Proximal enterocytes: 608.0;Proximal tubular cells: 397.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 127.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Group enriched" "Detected in many" 5 "cerebellum: 10.3;midbrain: 11.8;pons and medulla: 9.4" HPA046258 Enhanced Supported Nucleoplasm NA NA 170000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Macrophages - Innate immune response" Nucleoplasm "HPA046258: AB_10967205" "unprognostic (2.50e-1)" "unprognostic (1.49e-2)" "unprognostic (1.28e-1)" "unprognostic (1.72e-2)" "unprognostic (9.89e-3)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "prognostic favorable (5.62e-4)" "unprognostic (4.63e-2)" "unprognostic (1.67e-1)" "unprognostic (3.81e-1)" "unprognostic (2.31e-1)" "unprognostic (7.03e-3)" "unprognostic (9.28e-3)" "unprognostic (2.91e-2)" "unprognostic (1.84e-1)" "unprognostic (2.55e-1)" GCNT1 "C2GNT, NACGT2, NAGCT2" ENSG00000187210 "Glucosaminyl (N-acetyl) transferase 1" Q02742 9 76419850-76651203 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 48.5;parathyroid gland: 81.3;stomach 1: 38.0;thyroid gland: 20.9" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 50.5;Gastric mucus-secreting cells: 97.3;Mesothelial cells: 66.1;Proximal enterocytes: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 21.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Liver - Kupffer cells" "Group enriched" "Detected in all" 6 "cerebellum: 7.6;olfactory bulb: 24.9" "Low region specificity" "Detected in all" "HPA003522, HPA003523, HPA031151" Uncertain Supported "Nuclear speckles" NA NA 84000 "Cluster 29: Non-specific - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Nuclear speckles" "HPA003522: , HPA003523: , HPA031151: AB_10602904" "unprognostic (3.14e-1)" "unprognostic (2.01e-1)" "unprognostic (2.19e-1)" "prognostic favorable (8.44e-4)" "unprognostic (5.53e-2)" "unprognostic (2.41e-1)" "unprognostic (1.65e-2)" "unprognostic (3.37e-2)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.90e-1)" "unprognostic (3.06e-1)" "unprognostic (3.02e-3)" "unprognostic (4.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.80e-1)" "prognostic unfavorable (4.96e-4)" GDPD2 "FLJ20207, GDE3, OBDPF" ENSG00000130055 "Glycerophosphodiester phosphodiesterase domain containing 2" Q9HCC8 X 70423031-70433390 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 14.7;intestine: 20.2;lymphoid tissue: 57.7;skin 1: 46.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 38.3;Distal enterocytes: 31.4;Muller glia cells: 28.0;Proximal enterocytes: 94.9" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 6.2" "Colon - Colon enterocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Skin - Cornification" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "unprognostic (1.53e-3)" "unprognostic (5.79e-2)" "unprognostic (5.37e-2)" "unprognostic (5.00e-7)" "unprognostic (3.15e-3)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" "unprognostic (8.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.41e-2)" "unprognostic (5.52e-2)" "unprognostic (2.22e-1)" "unprognostic (8.91e-2)" GJB1 "CMTX, CMTX1, CX32" ENSG00000169562 "Gap junction protein beta 1" P08034 X 71212811-71225516 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 188.9;liver: 376.0;pancreas: 110.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 129.7;Distal enterocytes: 63.7;Exocrine glandular cells: 65.3;Hepatocytes: 261.0;Paneth cells: 62.7;Proximal enterocytes: 117.8;Undifferentiated cells: 62.9" "Cancer enhanced" "Detected in many" "liver cancer: 163.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 43.3;skin cancer: 83.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012994 Uncertain NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 30: White matter - Myelination" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 43: Hepatocytes - Metabolism" 37 "CAB012994: AB_2533228" "unprognostic (2.09e-2)" "unprognostic (1.39e-1)" "unprognostic (8.78e-2)" "unprognostic (2.71e-3)" "unprognostic (2.70e-1)" "unprognostic (4.11e-1)" "unprognostic (2.92e-1)" "unprognostic (3.68e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (7.36e-3)" "unprognostic (1.80e-1)" "prognostic favorable (2.85e-6)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (7.79e-2)" "unprognostic (4.97e-2)" GLOD5 ENSG00000171433 "Glyoxalase domain containing 5" A6NK44 X 48761747-48773648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 5.6;intestine: 10.3;kidney: 10.8;liver: 7.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 16.6;Paneth cells: 11.9;Proximal enterocytes: 47.9;Proximal tubular cells: 71.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010667 Enhanced Uncertain Mitochondria NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria "HPA010667: AB_1078975" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" "unprognostic (7.78e-2)" "unprognostic (7.04e-2)" "unprognostic (3.14e-1)" "unprognostic (6.11e-2)" "unprognostic (1.80e-2)" "unprognostic (2.64e-1)" "unprognostic (2.76e-1)" "unprognostic (2.21e-1)" "unprognostic (1.05e-8)" "unprognostic (2.08e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (6.79e-4)" HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989147 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroidogenesis" Oxidoreductase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 133.1" "Cell type enhanced" "Detected in many" "Ductal cells: 41.1;Hepatocytes: 57.6;Hofbauer cells: 48.1;Proximal enterocytes: 44.8;Proximal tubular cells: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 61.4;eosinophil: 27.3" "Lineage enriched" "Detected in many" 38 "granulocytes: 61.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015965, HPA050521, HPA060847" Approved Enhanced "Lipid droplets" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 42 "Lipid droplets" "HPA015965: , HPA050521: AB_2681155, HPA060847: AB_2684379" "unprognostic (5.41e-3)" "unprognostic (4.14e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.62e-2)" "unprognostic (5.06e-3)" "unprognostic (1.47e-2)" "unprognostic (3.52e-2)" "unprognostic (1.85e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (3.20e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (1.60e-6)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.79e-1)" IGSF23 ENSG00000216588 "Immunoglobulin superfamily member 23" A1L1A6 19 44613563-44636781 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 15.4;liver: 23.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.6;Enteroendocrine cells: 5.7;Hepatocytes: 14.6;Late spermatids: 11.7;Proximal enterocytes: 40.7" "Cancer enriched" "Detected in some" 10 "liver cancer: 12.4" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.4" "Cancer enhanced" "Detected in some" "Kidney cancer: 4.4" "Pancreas - Ductal cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051811 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA051811: AB_2681621" "unprognostic (1.54e-1)" "unprognostic (1.84e-3)" "unprognostic (5.74e-2)" "unprognostic (1.53e-3)" "unprognostic (4.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.20e-6)" "unprognostic (7.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.27e-2)" "unprognostic (2.93e-3)" "unprognostic (1.52e-1)" "unprognostic (1.19e-8)" "unprognostic (1.26e-1)" "unprognostic (6.38e-2)" "unprognostic (9.17e-2)" "unprognostic (2.85e-1)" IL22RA1 "CRF2-9, IL22R" ENSG00000142677 "Interleukin 22 receptor subunit alpha 1" Q8N6P7 1 24119771-24143140 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 193.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 19.4;Exocrine glandular cells: 7.2;Intestinal goblet cells: 15.7;Proximal enterocytes: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.2" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 35: Non-specific - DNA binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 60: Pancreatic exocrine cells - Proteolysis" 2 "unprognostic (1.68e-3)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-3)" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-3)" "unprognostic (1.12e-1)" "unprognostic (7.63e-2)" "unprognostic (1.72e-3)" "unprognostic (2.28e-1)" "unprognostic (4.78e-3)" "unprognostic (1.05e-2)" "unprognostic (2.57e-1)" "unprognostic (2.63e-1)" "unprognostic (1.64e-2)" KRT20 "CK20, K20, MGC35423" ENSG00000171431 "Keratin 20" P35900 17 40875889-40885242 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 629.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 2017.7;Enteroendocrine cells: 335.6;Intestinal goblet cells: 454.6;Paneth cells: 1576.2;Proximal enterocytes: 1249.8" "Group enriched" "Detected in many" 6 "colorectal cancer: 159.5;stomach cancer: 52.7;urothelial cancer: 99.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 41.5;colorectal cancer: 95.3;liver cancer: 50.6" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000032, HPA024309, HPA024684, HPA027236" Enhanced Supported "Intermediate filaments,Cytosol" NA NA 30000000 "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 32 "Intermediate filaments, Cytosol" "CAB000032: AB_2133718, HPA024309: AB_1852220, HPA024684: AB_1852222, HPA027236: AB_1852224" "unprognostic (3.49e-1)" "unprognostic (3.13e-1)" "unprognostic (1.71e-1)" "unprognostic (6.38e-3)" "unprognostic (5.12e-2)" "unprognostic (2.66e-3)" "prognostic unfavorable (7.05e-4)" "unprognostic (2.63e-2)" "unprognostic (4.87e-3)" "unprognostic (2.37e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (5.71e-2)" "unprognostic (6.30e-2)" "unprognostic (7.27e-2)" MYO15B MYO15BP ENSG00000266714 "Myosin XVB" 17 75587800-75626849 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 5 "intestine: 208.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.5;Intestinal goblet cells: 83.4;Paneth cells: 156.2;Proximal enterocytes: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.4;Gastric cancer: 16.9" "Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA022857, HPA023105" Approved Cytosol No No "Cluster 25: Small intestine - Absorption" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Cytosol "HPA022857: AB_1848813, HPA023105: AB_1859526" "prognostic favorable (9.34e-4)" "unprognostic (7.55e-2)" "unprognostic (6.99e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "unprognostic (5.59e-4)" "unprognostic (7.29e-3)" "unprognostic (1.48e-1)" "unprognostic (4.97e-2)" "unprognostic (2.28e-1)" "unprognostic (8.54e-3)" "unprognostic (1.04e-2)" "unprognostic (1.49e-1)" "unprognostic (6.39e-2)" "unprognostic (1.68e-1)" "unprognostic (3.35e-1)" "prognostic favorable (6.90e-5)" NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241809065-241817413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 74.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 75.0;Hepatocytes: 118.1;Intestinal goblet cells: 35.2;Oligodendrocyte precursor cells: 47.2;Paneth cells: 48.8;Proximal enterocytes: 68.6" "Group enriched" "Detected in some" 7 "colorectal cancer: 2.3;glioma: 6.0;liver cancer: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.2;liver cancer: 8.6" "Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037394 Enhanced NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 19: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 3 "HPA037394: AB_2675455" "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.85e-1)" "unprognostic (3.68e-4)" "unprognostic (3.76e-2)" "unprognostic (1.57e-1)" "unprognostic (8.70e-2)" "unprognostic (8.62e-2)" "unprognostic (1.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.92e-1)" "unprognostic (8.11e-4)" "unprognostic (2.00e-2)" "unprognostic (3.82e-1)" "unprognostic (6.64e-3)" "unprognostic (1.55e-2)" NOS2 "HEP-NOS, iNOS, NOS, NOS2A" ENSG00000007171 "Nitric oxide synthase 2" P35228 17 27756766-27800529 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 20.2;lymphoid tissue: 14.2" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 31.1;Granulosa cells: 6.3;Proximal enterocytes: 12.5;Undifferentiated cells: 12.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.7;Uterine cancer: 2.6" "Kidney - Endothelial cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002014 Enhanced NA NA "Cluster 25: Small intestine - Absorption" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "CAB002014: " "unprognostic (1.95e-3)" "unprognostic (3.08e-3)" "unprognostic (4.75e-3)" "unprognostic (4.42e-3)" "unprognostic (3.49e-1)" "unprognostic (2.13e-2)" "unprognostic (5.61e-2)" "unprognostic (5.09e-2)" "unprognostic (9.91e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "unprognostic (1.34e-1)" "unprognostic (6.04e-2)" "unprognostic (8.02e-2)" "unprognostic (3.68e-1)" "unprognostic (8.69e-2)" "unprognostic (4.03e-2)" NR5A2 "B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1" ENSG00000116833 "Nuclear receptor subfamily 5 group A member 2" O00482 1 200027614-200177420 "Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 17.3;liver: 37.4;pancreas: 59.2" "Cell type enhanced" "Detected in some" "Adipocytes: 23.6;Cholangiocytes: 22.9;Distal enterocytes: 39.3;Ductal cells: 44.1;Endothelial cells: 35.7;Exocrine glandular cells: 59.6;Hepatocytes: 34.2;Paneth cells: 27.7;Proximal enterocytes: 41.5;Undifferentiated cells: 25.2" "Cancer enhanced" "Detected in many" "liver cancer: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.3" "Cancer enhanced" "Detected in many" "cervical cancer: 12.2" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Region enhanced" "Detected in single" "hypothalamus: 1.2" "Low region specificity" "Detected in many" "HPA005455, HPA017067" Approved Uncertain "Nuclear speckles" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 24: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 45: Non-specific - Mixed function" "Nuclear speckles" "HPA005455: AB_1078140, HPA017067: AB_1844767" "unprognostic (7.47e-2)" "unprognostic (1.43e-1)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (1.19e-2)" "unprognostic (6.63e-3)" "unprognostic (4.46e-2)" "unprognostic (3.78e-2)" "unprognostic (3.34e-1)" "unprognostic (8.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.00e-7)" "unprognostic (5.48e-2)" "unprognostic (5.07e-2)" "unprognostic (9.23e-2)" "unprognostic (1.37e-1)" OSGIN1 "BDGI, OKL38" ENSG00000140961 "Oxidative stress induced growth inhibitor 1" Q9UJX0 16 83931311-83966332 "Predicted intracellular proteins" "Differentiation, Growth regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 143.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 75.7;Late spermatids: 334.7;Proximal enterocytes: 95.9" "Cancer enriched" "Detected in all" 5 "liver cancer: 65.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 12.7" "Group enriched" "Detected in many" 8 "granulocytes: 4.2;monocytes: 12.7" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 134.6" "Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA019239 Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 63: Late spermatids - Spermatogenesis" 30 "Nucleoplasm, Cytosol" "HPA019239: AB_1854779" "unprognostic (8.36e-2)" "unprognostic (9.44e-2)" "unprognostic (4.28e-2)" "prognostic favorable (4.89e-5)" "unprognostic (3.31e-3)" "unprognostic (9.14e-3)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (1.06e-1)" "unprognostic (2.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.20e-2)" "unprognostic (2.80e-2)" "unprognostic (2.45e-2)" "unprognostic (2.48e-2)" "unprognostic (8.28e-3)" "unprognostic (1.89e-1)" PECR "HSA250303, SDR29C1, TERP" ENSG00000115425 "Peroxisomal trans-2-enoyl-CoA reductase" Q9BY49 2 215996329-216082955 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 155.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 91.8;Proximal enterocytes: 51.4;Proximal tubular cells: 77.9" "Cancer enhanced" "Detected in all" "liver cancer: 30.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021593, HPA022539" Enhanced Supported Peroxisomes NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Peroxisomes "HPA021593: AB_1855177, HPA022539: AB_1855178" "unprognostic (7.97e-2)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (2.90e-1)" "unprognostic (6.40e-2)" "unprognostic (1.16e-3)" "unprognostic (3.56e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-3)" "unprognostic (5.61e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.63e-2)" "unprognostic (1.84e-2)" "unprognostic (7.75e-2)" "unprognostic (6.64e-2)" PLAAT2 "FLJ20556, HRASLS2, PLAAT-2" ENSG00000133328 "Phospholipase A and acyltransferase 2" Q9NWW9 11 63552770-63563379 "Enzymes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 65.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 78.8;Distal enterocytes: 73.3;Ionocytes: 52.3;Proximal enterocytes: 90.8;Proximal tubular cells: 152.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 8 "memory B-cell: 17.4;naive B-cell: 8.3" "Lineage enriched" "Detected in many" 10 "B-cells: 17.4" "Cancer enhanced" "Detected in many" "Myeloma: 30.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells" HPA058997 Approved Approved Mitochondria NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 25: Small intestine - Absorption" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 5 Mitochondria "HPA058997: AB_2683874" "unprognostic (4.76e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (9.69e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (1.38e-2)" "unprognostic (2.51e-1)" "unprognostic (2.43e-1)" "unprognostic (1.57e-2)" PLB1 "FLJ30866, PLB" ENSG00000163803 "Phospholipase B1" Q6P1J6 2 28457145-28644142 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 37.9" "Cell type enhanced" "Detected in many" "Early spermatids: 28.5;Extravillous trophoblasts: 31.2;Late spermatids: 18.5;Proximal enterocytes: 119.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "classical monocyte: 3.0;eosinophil: 3.0;intermediate monocyte: 4.4;myeloid DC: 5.7;neutrophil: 8.9;non-classical monocyte: 5.0" "Group enriched" "Detected in many" 40 "dendritic cells: 5.7;granulocytes: 8.9;monocytes: 5.0" "Low cancer specificity" "Detected in some" "Kidney - Macrophages, Lung - Neutrophil_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 33: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (2.18e-2)" "unprognostic (2.49e-1)" "unprognostic (6.58e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (4.91e-3)" "unprognostic (4.74e-2)" "unprognostic (4.48e-2)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" "unprognostic (2.17e-1)" "unprognostic (2.61e-9)" "unprognostic (2.48e-2)" "unprognostic (2.19e-2)" "unprognostic (4.99e-2)" "unprognostic (8.03e-2)" PNPLA1 "dJ50J22.1, FLJ38755" ENSG00000180316 "Patatin like phospholipase domain containing 1" Q8N8W4 6 36243203-36313955 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 23.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.8;Late spermatids: 1.7;monocytes: 2.2;Oligodendrocyte precursor cells: 1.4;Proximal enterocytes: 1.7;Proximal tubular cells: 5.6;Suprabasal keratinocytes: 2.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 69.9;eosinophil: 18.9" "Lineage enriched" "Detected in many" 17 "granulocytes: 69.9" "Cancer enhanced" "Detected in single" "Leukemia: 1.2" "Kidney - Proximal tubular cells, Lung - Neutrophil_2, Skin - Keratinocyte (other), Stomach - Parietal cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "unprognostic (3.57e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (3.95e-4)" "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (7.37e-2)" "unprognostic (2.49e-1)" "unprognostic (8.89e-2)" "unprognostic (1.13e-2)" "unprognostic (2.95e-1)" "unprognostic (2.76e-2)" "unprognostic (2.70e-2)" "unprognostic (9.85e-2)" "unprognostic (2.06e-1)" "unprognostic (2.04e-2)" "unprognostic (1.65e-2)" RHBDL1 "RHBDL, RRP" ENSG00000103269 "Rhomboid like 1" O75783 16 675671-678268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 36.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.4;Excitatory neurons: 29.1;Horizontal cells: 33.4;Inhibitory neurons: 25.9;Proximal enterocytes: 16.6;Rod photoreceptor cells: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030359, HPA030360, HPA046593" Uncertain Approved Nucleoplasm No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 8 Nucleoplasm "HPA030359: AB_2673445, HPA030360: AB_2673446, HPA046593: AB_2679711" "prognostic favorable (8.12e-4)" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.45e-1)" "unprognostic (2.07e-1)" "unprognostic (1.58e-2)" "unprognostic (3.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.78e-1)" "unprognostic (6.60e-3)" "unprognostic (2.74e-2)" "unprognostic (3.97e-2)" "unprognostic (5.63e-3)" "unprognostic (5.89e-2)" "unprognostic (1.27e-1)" "unprognostic (8.30e-3)" "unprognostic (1.49e-2)" SHBG "ABP, MGC126834, MGC138391, TEBG" ENSG00000129214 "Sex hormone binding globulin" P04278 17 7613946-7633382 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 61.5" "Cell type enhanced" "Detected in some" "Early spermatids: 51.9;Late spermatids: 124.0;Proximal enterocytes: 28.6" "Cancer enriched" "Detected in some" 28 "liver cancer: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Secreted to blood" Transport NA NA 9100000000 "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 36: Late spermatids - Unknown function" "unprognostic (3.35e-3)" "unprognostic (6.47e-2)" "unprognostic (5.65e-2)" "unprognostic (2.35e-1)" "unprognostic (8.84e-2)" "unprognostic (3.08e-1)" "unprognostic (3.50e-1)" "unprognostic (2.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.32e-3)" "unprognostic (3.58e-3)" "unprognostic (2.21e-1)" "unprognostic (4.49e-2)" "unprognostic (7.83e-3)" "unprognostic (4.35e-1)" "unprognostic (5.50e-3)" "unprognostic (1.06e-1)" SLC25A34 DKFZp781A10161 ENSG00000162461 "Solute carrier family 25 member 34" Q6PIV7 1 15736258-15741392 "Predicted membrane proteins, Transporters" Transport "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "brain: 15.8;heart muscle: 13.9;intestine: 13.4;skeletal muscle: 36.5;tongue: 44.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 16.5;Paneth cells: 12.4;Proximal enterocytes: 40.3;Skeletal myocytes: 12.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069806 Approved Mitochondria NA NA "Cluster 11: T-cells - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 5: Enterocytes - Absorption" Mitochondria "HPA069806: AB_2686202" "unprognostic (2.06e-1)" "unprognostic (4.72e-1)" "unprognostic (1.15e-1)" "unprognostic (2.43e-1)" "unprognostic (2.58e-1)" "unprognostic (8.08e-3)" "unprognostic (1.98e-2)" "unprognostic (9.92e-2)" "unprognostic (1.55e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-4)" "unprognostic (5.74e-2)" "unprognostic (6.10e-2)" "unprognostic (4.02e-1)" "unprognostic (1.82e-1)" "unprognostic (4.04e-2)" "unprognostic (2.40e-4)" SLC39A4 "AEZ, AWMS2, ZIP4" ENSG00000147804 "Solute carrier family 39 member 4" Q6P5W5 8 144409742-144416844 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 85.4" "Cell type enhanced" "Detected in many" "Oocytes: 258.8;Proximal enterocytes: 393.6;Proximal tubular cells: 231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (2.59e-1)" "unprognostic (2.35e-3)" "unprognostic (9.16e-2)" "unprognostic (3.84e-2)" "unprognostic (5.63e-3)" "unprognostic (1.46e-1)" "unprognostic (5.40e-2)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (3.28e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "prognostic favorable (9.04e-4)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (9.04e-3)" "unprognostic (1.87e-1)" SLC6A20 "IMINO, SIT1, XT3, Xtrp3" ENSG00000163817 "Solute carrier family 6 member 20" Q9NP91 3 45755449-45796574 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 48.6;intestine: 24.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.3;Ductal cells: 15.1;Gastric mucus-secreting cells: 17.1;Oocytes: 25.0;Proximal enterocytes: 69.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 12 "choroid plexus: 114.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 4.1;colorectal cancer: 12.9;Gastric cancer: 10.7;pancreatic cancer: 6.8" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 8 "unprognostic (1.57e-1)" "unprognostic (5.26e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-2)" "unprognostic (1.48e-1)" "unprognostic (9.43e-3)" "unprognostic (3.26e-2)" "unprognostic (4.33e-3)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (1.46e-1)" "prognostic favorable (1.55e-5)" "unprognostic (2.87e-1)" "unprognostic (1.23e-1)" "unprognostic (7.55e-2)" "unprognostic (2.09e-2)" TMEM171 PRP2 ENSG00000157111 "Transmembrane protein 171" Q8WVE6 5 73120569-73131809 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 34.4;kidney: 10.4;lymphoid tissue: 14.0;stomach 1: 24.7;thyroid gland: 30.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.6;Cholangiocytes: 34.3;Distal enterocytes: 98.6;Paneth cells: 53.8;Proximal enterocytes: 45.5;Undifferentiated cells: 49.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "MAIT T-cell: 24.1;memory CD8 T-cell: 8.2" "Lineage enriched" "Detected in single" 89 "T-cells: 24.1" "Cancer enhanced" "Detected in many" "skin cancer: 26.1" "Colon - Colon enterocytes, Stomach - Parietal cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 4.9" HPA042308 Approved NA NA "Cluster 1: T-cells - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 5: Enterocytes - Absorption" "HPA042308: AB_10796901" "unprognostic (7.34e-2)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (7.74e-3)" "unprognostic (2.81e-5)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (1.44e-3)" "unprognostic (1.77e-1)" "unprognostic (1.85e-1)" "unprognostic (4.20e-2)" "unprognostic (1.22e-1)" "prognostic favorable (3.93e-10)" "unprognostic (6.13e-3)" "unprognostic (2.43e-1)" "unprognostic (9.10e-3)" "unprognostic (1.57e-1)" TMEM176B "LR8, MS4B2" ENSG00000106565 "Transmembrane protein 176B" Q3YBM2 7 150791285-150801360 "Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 1609.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 1117.7;Paneth cells: 750.0;Proximal enterocytes: 925.4;Proximal tubular cells: 740.7;Schwann cells: 424.7" "Cancer enhanced" "Detected in all" "liver cancer: 537.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 866.3;intermediate monocyte: 586.7" "Lineage enriched" "Detected in many" 5 "monocytes: 866.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.7" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047509 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 22: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 4 "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA047509: AB_2680072" "unprognostic (5.21e-2)" "unprognostic (7.86e-2)" "unprognostic (1.30e-2)" "unprognostic (8.27e-2)" "unprognostic (3.35e-2)" "unprognostic (6.96e-2)" "unprognostic (7.23e-2)" "unprognostic (2.74e-2)" "unprognostic (5.31e-2)" "unprognostic (1.47e-1)" "unprognostic (5.72e-3)" "unprognostic (7.50e-2)" "unprognostic (3.11e-3)" "unprognostic (5.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.05e-2)" TMEM252 "C9orf71, MGC34760" ENSG00000181778 "Transmembrane protein 252" Q8N6L7 9 68536580-68540883 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 21.4;kidney: 34.4" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 5.6;Proximal enterocytes: 23.1;Proximal tubular cells: 11.2" "Cancer enriched" "Detected in many" 17 "renal cancer: 35.7" "Region enhanced" "Detected in single" "cerebellum: 2.6" "Immune cell enriched" "Detected in single" 8 "neutrophil: 4.1" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.1" "Group enriched" "Detected in some" 7 "ovarian cancer: 1.0;Uterine cancer: 2.3" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA079457 Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" 4 "HPA079457: " "unprognostic (2.64e-1)" "unprognostic (3.28e-3)" "unprognostic (3.72e-1)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (4.00e-2)" "unprognostic (7.79e-3)" "unprognostic (6.47e-2)" "unprognostic (1.64e-2)" "unprognostic (6.42e-2)" "prognostic favorable (1.75e-7)" "unprognostic (7.63e-2)" "unprognostic (6.15e-2)" "unprognostic (7.66e-2)" "unprognostic (2.50e-1)" UNC5CL "MGC34763, ZUD" ENSG00000124602 "Unc-5 family C-terminal like" Q8IV45 6 41026895-41039221 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 36.0;kidney: 57.0;liver: 51.5;pancreas: 35.1;stomach 1: 23.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 34.3;Ductal cells: 35.2;Exocrine glandular cells: 83.8;Gastric mucus-secreting cells: 37.7;Hepatocytes: 24.3;Proximal enterocytes: 32.5;Proximal tubular cells: 42.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA015725 Enhanced Approved Centrosome NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 28: Non-specific - Nuclear processes" "Cluster 38: Proximal tubular cells - Transmembrane transport" 5 Centrosome "HPA015725: AB_2669283" "unprognostic (1.10e-2)" "unprognostic (3.59e-2)" "unprognostic (1.60e-1)" "unprognostic (2.57e-1)" "unprognostic (7.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.16e-1)" "unprognostic (8.55e-3)" "unprognostic (3.58e-1)" "unprognostic (2.02e-2)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" "unprognostic (9.30e-2)" "unprognostic (2.35e-1)" "unprognostic (2.31e-1)" "unprognostic (1.19e-1)" "unprognostic (5.60e-6)" VILL ENSG00000136059 "Villin like" O15195 3 37988059-38007188 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "intestine: 53.4;stomach 1: 85.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 180.2;Gastric mucus-secreting cells: 178.0;Intestinal goblet cells: 93.1;Paneth cells: 110.2;Proximal enterocytes: 150.5" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 57.2" "Heart muscle - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA035675, HPA035676" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA035675: AB_10671223, HPA035676: " "unprognostic (7.86e-3)" "unprognostic (7.37e-3)" "unprognostic (1.43e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (1.35e-4)" "prognostic favorable (1.75e-4)" "unprognostic (1.69e-1)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "unprognostic (2.18e-1)" "unprognostic (1.03e-2)" "unprognostic (2.95e-2)" "unprognostic (3.66e-3)" "unprognostic (5.55e-2)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (7.43e-3)" XDH "XO, XOR" ENSG00000158125 "Xanthine dehydrogenase" P47989 2 31334321-31414742 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 40.8;intestine: 48.1;liver: 66.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 252.4;Distal enterocytes: 68.7;Hepatocytes: 41.3;Proximal enterocytes: 98.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.0" "Colon - Colon enterocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062641, HPA069323" Supported Uncertain Nucleoplasm,Nucleoli "Intracellular and membrane" Enzyme No No 77000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 17: Breast glandular cells - Lactation" Nucleoplasm Nucleoli "HPA062641: AB_2684816, HPA069323: AB_2686121" "unprognostic (8.58e-2)" "unprognostic (4.07e-2)" "unprognostic (1.34e-2)" "unprognostic (1.79e-1)" "unprognostic (2.08e-2)" "unprognostic (7.06e-2)" "unprognostic (4.38e-3)" "unprognostic (7.48e-3)" "unprognostic (3.55e-1)" "unprognostic (3.60e-2)" "unprognostic (3.95e-3)" "unprognostic (3.51e-2)" "unprognostic (1.24e-6)" "unprognostic (2.25e-1)" "unprognostic (5.25e-2)" "unprognostic (2.54e-1)" "prognostic favorable (8.73e-6)" ACAA1 Lnc-Myd88 ENSG00000060971 "Acetyl-CoA acyltransferase 1" P09110 3 38103129-38137242 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 204.7;liver: 638.8" "Cell type enhanced" "Detected in all" "Distal enterocytes: 388.0;Hepatocytes: 782.2;Proximal enterocytes: 422.5;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006764, HPA007244" Enhanced Supported Peroxisomes NA NA 4700000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 3 Peroxisomes "HPA006764: AB_1078085, HPA007244: AB_1078084" "prognostic favorable (3.00e-4)" "unprognostic (5.57e-2)" "unprognostic (4.54e-2)" "prognostic favorable (7.53e-4)" "unprognostic (2.63e-1)" "prognostic favorable (1.23e-4)" "unprognostic (9.35e-3)" "unprognostic (2.91e-2)" "unprognostic (8.11e-2)" "unprognostic (2.22e-1)" "unprognostic (2.24e-1)" "unprognostic (4.90e-1)" "prognostic favorable (6.99e-9)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (1.65e-2)" ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 171.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 92.5;Proximal enterocytes: 29.6;Proximal tubular cells: 40.4" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Region enriched" "Detected in all" 5 "choroid plexus: 30.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0;liver cancer: 3.4" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 43: Hepatocytes - Metabolism" 1 Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 1117.1;retina: 1147.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.1;Cone photoreceptor cells: 319.4;Horizontal cells: 170.0;Proximal enterocytes: 127.3;Rod photoreceptor cells: 243.2" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 150000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 17: Neuronal - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 66: Photoreceptor cells - Visual perception" 3 "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" CBS HIP4 ENSG00000160200 "Cystathionine beta-synthase" P35520 21 43053191-43076943 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" "Allosteric enzyme, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 52.0;liver: 170.6;pancreas: 131.6" "Cell type enhanced" "Detected in some" "Hepatocytes: 2.6;Paneth cells: 2.4;Proximal enterocytes: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 65 "neutrophil: 6.5" "Lineage enriched" "Detected in single" 65 "granulocytes: 6.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001223 Enhanced Approved Nucleoli,Vesicles NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 62: Hepatocytes - Metabolism" 17 Vesicles Nucleoli "HPA001223: AB_1846112" "unprognostic (4.86e-2)" "unprognostic (1.48e-2)" "unprognostic (6.81e-2)" "unprognostic (1.12e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.68e-4)" "unprognostic (3.62e-1)" "unprognostic (6.76e-3)" "unprognostic (1.06e-1)" "unprognostic (6.50e-2)" "unprognostic (2.13e-1)" "unprognostic (1.61e-2)" "unprognostic (6.73e-3)" "unprognostic (2.62e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-1)" CYP2J2 ENSG00000134716 "Cytochrome P450 family 2 subfamily J member 2" P51589 1 59893308-59926773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 86.5;intestine: 81.0;liver: 141.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 109.3;Cytotrophoblasts: 115.0;Oligodendrocytes: 63.7;Proximal enterocytes: 116.3;Syncytiotrophoblasts: 252.2" "Cancer enhanced" "Detected in many" "renal cancer: 32.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.9;naive CD8 T-cell: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.3" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Intracellular and membrane" Enzyme NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Cytotrophoblasts - Mitochondria" "unprognostic (3.53e-2)" "unprognostic (1.22e-2)" "unprognostic (1.35e-2)" "unprognostic (1.99e-2)" "unprognostic (2.51e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (3.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.84e-2)" "unprognostic (7.29e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (5.54e-7)" "unprognostic (4.96e-1)" "unprognostic (8.45e-2)" "unprognostic (4.25e-1)" "unprognostic (9.70e-2)" DNAJC22 "FLJ13236, wus" ENSG00000178401 "DnaJ heat shock protein family (Hsp40) member C22" Q8N4W6 12 49346888-49357546 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 23.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 42.0;Distal enterocytes: 34.4;Enteroendocrine cells: 32.6;Hepatocytes: 38.1;Intestinal goblet cells: 31.4;Mesothelial cells: 27.6;Paneth cells: 33.6;Proximal enterocytes: 55.9;Undifferentiated cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Region enhanced" "Detected in single" "midbrain: 1.2" "Low region specificity" "Detected in all" HPA039953 Approved Vesicles NA NA "Cluster 83: Liver - Metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" Vesicles "HPA039953: AB_2676770" "unprognostic (5.23e-2)" "unprognostic (1.24e-1)" "unprognostic (9.01e-2)" "prognostic favorable (4.56e-5)" "unprognostic (4.77e-3)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (4.05e-2)" "prognostic unfavorable (7.54e-4)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (3.18e-2)" "unprognostic (9.35e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-2)" FUOM "C10orf125, FLJ26016, FucM, FucU" ENSG00000148803 "Fucose mutarotase" A2VDF0 10 133355158-133358025 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 222.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 621.7;Hofbauer cells: 176.9;Proximal enterocytes: 735.4;Proximal tubular cells: 325.9" "Cancer enriched" "Detected in all" 5 "liver cancer: 61.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039207 Approved NA NA 2000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 43: Hepatocytes - Metabolism" "HPA039207: AB_10795033" "unprognostic (1.15e-2)" "unprognostic (1.16e-1)" "unprognostic (4.48e-2)" "unprognostic (7.19e-2)" "unprognostic (4.82e-1)" "unprognostic (2.66e-2)" "unprognostic (1.66e-2)" "unprognostic (2.45e-1)" "unprognostic (6.25e-2)" "unprognostic (7.56e-2)" "unprognostic (4.50e-2)" "unprognostic (8.67e-2)" "unprognostic (3.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.50e-1)" "unprognostic (4.88e-3)" "unprognostic (1.65e-1)" GAL3ST1 CST ENSG00000128242 "Galactose-3-O-sulfotransferase 1" Q99999 22 30554635-30574665 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 63.9;intestine: 23.7;kidney: 17.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 34.3;Muller glia cells: 33.8;Oligodendrocyte precursor cells: 25.0;Oligodendrocytes: 49.9;Proximal enterocytes: 42.9" "Cancer enriched" "Detected in many" 6 "renal cancer: 38.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 16 "Kidney cancer: 235.5" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001220, HPA077138" Approved Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" Vesicles Nucleoplasm "HPA001220: AB_1078933, HPA077138: " "unprognostic (2.69e-2)" "unprognostic (3.12e-4)" "unprognostic (5.93e-2)" "unprognostic (1.08e-2)" "unprognostic (2.32e-1)" "unprognostic (6.50e-3)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "unprognostic (2.89e-1)" "unprognostic (5.18e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" GDA "CYPIN, GAH" ENSG00000119125 "Guanine deaminase" Q9Y2T3 9 72114595-72257193 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 71.1;intestine: 92.1;kidney: 41.4;liver: 58.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 105.6;Glandular and luminal cells: 132.5;Proximal enterocytes: 289.3;Proximal tubular cells: 80.8" "Cancer enhanced" "Detected in many" "renal cancer: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid - Parafollicular cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "amygdala: 50.6;basal ganglia: 42.2;cerebral cortex: 84.8;hippocampal formation: 98.5;olfactory bulb: 26.5" "HPA019352, HPA024099, HPA030387" Enhanced Approved Nucleoplasm No NA 1500000 "Cluster 25: Small intestine - Absorption" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" 1 Nucleoplasm "HPA019352: AB_1855593, HPA024099: AB_1855594, HPA030387: AB_10602351" "unprognostic (2.64e-2)" "unprognostic (7.10e-2)" "unprognostic (2.83e-2)" "unprognostic (2.92e-1)" "unprognostic (4.35e-2)" "unprognostic (8.45e-2)" "unprognostic (2.00e-1)" "unprognostic (5.60e-2)" "unprognostic (3.26e-1)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (5.56e-2)" "prognostic favorable (2.66e-5)" "unprognostic (2.23e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (8.30e-4)" GPR15LG "AP-57, C10orf99, CSBF, FLJ21763, GPR15L, RLLV1833, UNQ1833" ENSG00000188373 "G protein-coupled receptor 15 ligand" Q6UWK7 10 84173801-84185294 "Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Cytokine" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 187.8;intestine: 265.9;vagina: 111.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 1331.7;Enteroendocrine cells: 271.4;Intestinal goblet cells: 217.5;Paneth cells: 776.7;Proximal enterocytes: 345.9;Suprabasal keratinocytes: 408.3;Undifferentiated cells: 211.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 91.5;head and neck cancer: 102.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 26.7;head and neck cancer: 7.5" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050920 Enhanced "Secreted in other tissues" Cytokine NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "HPA050920: AB_2681274" "unprognostic (3.13e-2)" "unprognostic (1.43e-1)" "unprognostic (6.04e-2)" "unprognostic (1.78e-2)" "unprognostic (7.46e-3)" "unprognostic (2.05e-1)" "unprognostic (7.98e-2)" "unprognostic (2.04e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (3.70e-1)" "unprognostic (4.67e-2)" HHLA2 "B7-H5, B7-H7, B7H7, B7y" ENSG00000114455 "HERV-H LTR-associating 2" Q9UM44 3 108296529-108378285 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 134.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 26.7;Distal enterocytes: 160.5;Exocrine glandular cells: 41.6;Proximal enterocytes: 171.7" "Group enriched" "Detected in many" 12 "colorectal cancer: 9.2;lung cancer: 5.0;pancreatic cancer: 5.1;renal cancer: 16.6;stomach cancer: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.4;Rhabdoid: 15.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA055478 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 5: Enterocytes - Absorption" 13 "HPA055478: AB_2682830" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.11e-1)" "unprognostic (2.30e-1)" "unprognostic (1.59e-2)" "unprognostic (8.14e-5)" "unprognostic (1.76e-1)" "unprognostic (2.28e-1)" "unprognostic (1.08e-1)" "unprognostic (6.42e-3)" "unprognostic (1.24e-1)" "unprognostic (1.62e-3)" "unprognostic (1.47e-1)" "unprognostic (2.31e-1)" "unprognostic (2.67e-1)" "unprognostic (1.66e-2)" HNF4A "HNF4, MODY, MODY1, NR2A1, TCF14" ENSG00000101076 "Hepatocyte nuclear factor 4 alpha" P41235 20 44355699-44432845 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 99.3;kidney: 44.1;liver: 114.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 163.1;Enteroendocrine cells: 66.0;Hepatocytes: 174.9;Intestinal goblet cells: 67.3;Paneth cells: 89.0;Proximal enterocytes: 137.0;Proximal tubular cells: 161.2;Undifferentiated cells: 78.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 48.2;liver cancer: 38.4" "Region enriched" "Detected in all" 10 "choroid plexus: 32.2" "Immune cell enhanced" "Detected in single" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "Bile duct cancer: 19.2;colorectal cancer: 57.4;Gastric cancer: 33.3;liver cancer: 41.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004712, CAB019417" Enhanced Supported Nucleoplasm NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 4 Nucleoplasm "CAB019417: AB_2295208, HPA004712: AB_1079075" "unprognostic (2.47e-1)" "unprognostic (3.08e-1)" "unprognostic (2.34e-1)" "unprognostic (2.29e-1)" "unprognostic (8.54e-2)" "unprognostic (1.56e-2)" "unprognostic (6.90e-2)" "unprognostic (4.79e-3)" "unprognostic (2.59e-2)" "unprognostic (3.77e-2)" "unprognostic (2.45e-2)" "unprognostic (1.05e-1)" "unprognostic (2.75e-2)" "unprognostic (8.40e-3)" "unprognostic (2.12e-1)" "unprognostic (2.70e-2)" HOXB7 "HOX2, HOX2C" ENSG00000260027 "Homeobox B7" P09629 17 48607232-48633572 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "epididymis: 131.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 130.8;Collecting duct cells: 87.5;Distal enterocytes: 119.3;Distal tubular cells: 129.1;Glandular and luminal cells: 79.6;Intestinal goblet cells: 76.4;Paneth cells: 70.7;Proximal enterocytes: 117.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 35 "medulla oblongata: 11.5;spinal cord: 27.9;white matter: 15.6" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Prostate - Endothelial cells" "Region enriched" "Detected in single" 58 "pons and medulla: 5.7" "Region enriched" "Detected in some" 7 "spinal cord: 29.1" HPA049940 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 22: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 5 "Nucleoplasm, Nuclear bodies" Cytosol "HPA049940: AB_2616461" "unprognostic (6.76e-2)" "unprognostic (6.76e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-1)" "unprognostic (1.39e-3)" "unprognostic (1.42e-2)" "unprognostic (1.69e-2)" "unprognostic (8.05e-3)" "unprognostic (9.16e-2)" "unprognostic (9.91e-2)" "unprognostic (7.01e-3)" "unprognostic (7.81e-3)" "unprognostic (1.17e-2)" "unprognostic (1.56e-2)" "unprognostic (1.06e-1)" "unprognostic (2.41e-1)" "prognostic favorable (2.39e-4)" HSD11B2 SDR9C3 ENSG00000176387 "Hydroxysteroid 11-beta dehydrogenase 2" P80365 16 67430652-67437553 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 243.0;kidney: 326.2;salivary gland: 252.7" "Cell type enhanced" "Detected in many" "Collecting duct cells: 140.0;Distal enterocytes: 701.0;Enteroendocrine cells: 133.5;Intestinal goblet cells: 254.5;Paneth cells: 272.9;Proximal enterocytes: 247.9;Syncytiotrophoblasts: 165.6" "Cancer enhanced" "Detected in all" "renal cancer: 62.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.0;prostate cancer: 15.6" "Colon - Colon enterocytes, Kidney - Intercalated cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB032443, HPA042186, HPA056385" Enhanced Supported Vesicles NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Vesicles "CAB032443: AB_2233199, HPA042186: AB_2677888, HPA056385: AB_2683110" "unprognostic (2.87e-3)" "unprognostic (5.24e-2)" "unprognostic (7.10e-2)" "unprognostic (6.55e-2)" "unprognostic (9.29e-3)" "unprognostic (3.14e-1)" "unprognostic (2.68e-2)" "unprognostic (2.07e-1)" "unprognostic (2.21e-3)" "unprognostic (2.25e-3)" "unprognostic (3.27e-2)" "unprognostic (2.34e-1)" "prognostic favorable (9.51e-5)" "unprognostic (7.20e-2)" "unprognostic (3.19e-1)" "unprognostic (1.55e-2)" "unprognostic (1.84e-1)" HSD17B2 "HSD17, SDR9C2" ENSG00000086696 "Hydroxysteroid 17-beta dehydrogenase 2" P37059 16 82035004-82098534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 416.6;liver: 211.1;placenta: 368.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 148.8;Distal enterocytes: 179.9;Hepatocytes: 120.4;Paneth cells: 202.6;Proximal enterocytes: 399.3" "Group enriched" "Detected in many" 4 "liver cancer: 10.9;pancreatic cancer: 6.5;stomach cancer: 4.2;urothelial cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 31.8;pancreatic cancer: 35.3" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Group enriched" "Detected in some" 5 "midbrain: 2.2;pons and medulla: 3.4" "Not detected" "Not detected" "HPA021826, HPA050235" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 5: Enterocytes - Absorption" "Endoplasmic reticulum" "HPA021826: AB_10961148, HPA050235: AB_2681059" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.48e-2)" "unprognostic (2.58e-1)" "unprognostic (1.77e-1)" "unprognostic (4.29e-2)" "unprognostic (2.60e-1)" "unprognostic (7.35e-2)" "unprognostic (6.05e-3)" "unprognostic (4.98e-2)" "unprognostic (7.35e-2)" "unprognostic (6.31e-4)" "unprognostic (5.39e-2)" "unprognostic (1.14e-1)" "unprognostic (4.30e-2)" "prognostic favorable (3.83e-4)" LY75 "CD205, CLEC13B, DEC-205" ENSG00000054219 "Lymphocyte antigen 75" O60449 2 159803355-159904756 "CD markers, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 76.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 20.7;Distal enterocytes: 19.7;Proximal enterocytes: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 19.6;Myeloma: 18.0" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB001450, HPA049108, HPA054073" Enhanced Approved "Golgi apparatus" NA NA 1300000 "Cluster 24: Non-specific - Transcription" "Cluster 71: Thymus - Adaptive immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" "Golgi apparatus" "CAB001450: AB_563525, HPA049108: AB_2680635, HPA054073: AB_2682370" "unprognostic (7.29e-3)" "unprognostic (1.92e-3)" "unprognostic (3.15e-1)" "unprognostic (1.52e-2)" "unprognostic (4.60e-3)" "unprognostic (3.65e-2)" "unprognostic (8.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.80e-1)" "unprognostic (2.36e-1)" "unprognostic (8.74e-3)" "unprognostic (3.92e-1)" "prognostic unfavorable (2.39e-5)" "unprognostic (2.66e-1)" "unprognostic (4.89e-2)" "unprognostic (1.94e-2)" "prognostic favorable (3.86e-4)" MNX1 "HB9, HLXB9, HOXHB9, SCRA1" ENSG00000130675 "Motor neuron and pancreas homeobox 1" P50219 7 156994051-157010663 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 7.0;pancreas: 15.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 9.1;Ductal cells: 5.8;Enteroendocrine cells: 17.1;Intestinal goblet cells: 16.9;Oocytes: 6.6;Pancreatic endocrine cells: 8.5;Proximal enterocytes: 6.6;Undifferentiated cells: 10.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 41 "spinal cord: 4.1" HPA071717 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 48: Stomach - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 60: Pancreatic exocrine cells - Proteolysis" Nucleoplasm "Nucleoli, Cytosol" "HPA071717: AB_2686437" "unprognostic (2.01e-1)" "unprognostic (1.21e-1)" "unprognostic (1.87e-2)" "unprognostic (3.72e-3)" "unprognostic (8.85e-2)" "unprognostic (1.08e-2)" "unprognostic (2.07e-1)" "unprognostic (4.07e-2)" "unprognostic (5.06e-2)" "unprognostic (8.62e-4)" "unprognostic (1.00e-2)" "unprognostic (3.35e-2)" "unprognostic (2.23e-5)" "unprognostic (1.67e-3)" "unprognostic (5.80e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" PBLD "FLJ14767, MAWBP, MAWDBP" ENSG00000108187 "Phenazine biosynthesis like protein domain containing" P30039 10 68282660-68333049 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 166.0;kidney: 260.0;liver: 324.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.5;Hepatocytes: 208.2;Proximal enterocytes: 357.9;Proximal tubular cells: 327.7" "Cancer enhanced" "Detected in all" "liver cancer: 16.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038035, HPA038036" Enhanced Approved Vesicles NA NA 1100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" 8 Vesicles "HPA038035: AB_10672470, HPA038036: AB_10675625" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (6.14e-2)" "unprognostic (8.83e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "prognostic favorable (1.44e-4)" "unprognostic (8.25e-2)" "unprognostic (3.62e-2)" "unprognostic (3.36e-3)" "unprognostic (1.19e-1)" "unprognostic (6.26e-3)" "unprognostic (3.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.07e-2)" "unprognostic (8.28e-2)" "unprognostic (6.68e-2)" PLA2G2A "PLA2B, PLA2L" ENSG00000188257 "Phospholipase A2 group IIA" P14555 1 19975431-19980416 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Inflammatory response, Lipid metabolism, Phospholipid metabolism" "Antimicrobial, Bacteriolytic enzyme, Hydrolase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 904.0;intestine: 1462.3;placenta: 558.1;urinary bladder: 630.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 640.8;Exocrine glandular cells: 430.1;Fibroblasts: 1056.7;Mesothelial cells: 1444.4;Proximal enterocytes: 427.4;Undifferentiated cells: 2509.4" "Cancer enhanced" "Detected in all" "prostate cancer: 875.7" "Region enhanced" "Detected in some" "choroid plexus: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 84.8;Gastric cancer: 164.6" "Colon - Macrophages, Lung - Fibroblast_2, Thyroid - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" HPA015236 Enhanced "Secreted to blood" Enzyme NA NA 1000000 680000 "Cluster 45: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA015236: AB_10601047" "unprognostic (2.33e-2)" "unprognostic (1.28e-1)" "unprognostic (2.79e-2)" "unprognostic (7.85e-3)" "unprognostic (8.71e-2)" "unprognostic (9.27e-2)" "unprognostic (2.02e-1)" "unprognostic (1.80e-1)" "prognostic favorable (1.49e-4)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" "unprognostic (1.58e-2)" "unprognostic (3.77e-15)" "unprognostic (2.72e-2)" "unprognostic (9.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.51e-1)" PLEKHS1 "bA211N11.2, C10orf81, FLJ23537" ENSG00000148735 "Pleckstrin homology domain containing S1" Q5SXH7 10 113751262-113783429 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "breast: 24.0;cervix: 47.4;intestine: 35.7;pancreas: 26.2;salivary gland: 41.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 36.2;Ciliated cells: 83.5;Club cells: 72.6;Ionocytes: 113.0;Mucus glandular cells: 52.3;Proximal enterocytes: 42.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 14.3;breast cancer: 16.2" "Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA037583 Approved Vesicles,Centrosome NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" Centrosome Vesicles "HPA037583: AB_10671762" "unprognostic (2.64e-1)" "unprognostic (1.64e-2)" "unprognostic (2.74e-2)" "unprognostic (3.60e-2)" "unprognostic (1.07e-1)" "unprognostic (2.63e-2)" "unprognostic (1.74e-2)" "unprognostic (2.36e-2)" "unprognostic (8.43e-2)" "unprognostic (6.82e-2)" "unprognostic (2.57e-1)" "unprognostic (1.21e-2)" "unprognostic (0.00e+0)" "unprognostic (4.00e-3)" "unprognostic (2.19e-1)" "unprognostic (2.27e-1)" "prognostic favorable (1.03e-4)" RNASE4 RAB1 ENSG00000258818 "Ribonuclease A family member 4" P34096 14 20684560-20701216 "Plasma proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 463.8" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 56.1;Gastric mucus-secreting cells: 48.9;Hepatocytes: 47.7;Intestinal goblet cells: 97.9;Proximal enterocytes: 38.9" "Cancer enhanced" "Detected in many" "liver cancer: 6.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Enzyme NA NA 61000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "unprognostic (5.21e-2)" "unprognostic (3.18e-4)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "prognostic favorable (9.62e-5)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.29e-1)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (9.16e-2)" "unprognostic (4.27e-2)" S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3615.1;vagina: 1138.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2161.5;Distal enterocytes: 1962.1;Proximal enterocytes: 1520.7;Squamous epithelial cells: 3669.3;Suprabasal keratinocytes: 5409.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1004.1" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" 3 "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" SELENOP "SELP, SeP, SEPP, SEPP1" ENSG00000250722 "Selenoprotein P" P49908 5 42799880-42887392 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 2030.1;liver: 6077.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 3136.6;Proximal enterocytes: 5404.0" "Cancer enriched" "Detected in all" 4 "liver cancer: 116.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 182.2" "Liver - Hepatocytes, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" HPA036287 Approved Uncertain "Nucleoplasm,Golgi apparatus" "Secreted to blood" "No annotated function" NA NA 2220000000 1800000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 1 "Nucleoplasm, Golgi apparatus" "HPA036287: AB_10794618" "unprognostic (7.96e-2)" "unprognostic (2.10e-1)" "unprognostic (4.28e-3)" "unprognostic (1.19e-3)" "unprognostic (6.67e-2)" "unprognostic (6.37e-2)" "unprognostic (9.22e-2)" "unprognostic (2.19e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (2.07e-2)" "unprognostic (1.05e-1)" "prognostic favorable (6.97e-6)" "unprognostic (1.35e-2)" "unprognostic (4.19e-2)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" SLC25A23 "APC2, FLJ30339, MGC2615" ENSG00000125648 "Solute carrier family 25 member 23" Q9BV35 19 6436079-6465203 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 390.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 128.7;Proximal enterocytes: 98.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009675, HPA050883" Approved Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 1 Mitochondria "HPA009675: AB_2668252, HPA050883: AB_2681260" "unprognostic (3.51e-1)" "unprognostic (1.53e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.05e-2)" "unprognostic (3.65e-3)" "unprognostic (3.43e-2)" "unprognostic (1.31e-3)" "unprognostic (1.27e-1)" "unprognostic (3.82e-1)" "unprognostic (1.30e-1)" "unprognostic (3.25e-1)" "prognostic favorable (1.10e-12)" "unprognostic (8.95e-2)" "unprognostic (3.20e-1)" "unprognostic (5.44e-2)" "unprognostic (4.22e-1)" SLC28A2 "CNT2, HCNT2, HsT17153, SPNT1" ENSG00000137860 "Solute carrier family 28 member 2" O43868 15 45252234-45277846 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 89.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 11.7;Distal enterocytes: 27.1;Paneth cells: 29.0;Proximal enterocytes: 42.3;Undifferentiated cells: 23.1" "Cancer enhanced" "Detected in many" "stomach cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Gastric cancer: 7.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046068, HPA055623" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" Vesicles "Golgi apparatus" "HPA046068: AB_2679523, HPA055623: AB_2682866" "unprognostic (2.75e-1)" "unprognostic (2.34e-2)" "unprognostic (1.62e-3)" "unprognostic (5.46e-2)" "unprognostic (1.13e-1)" "unprognostic (6.85e-2)" "unprognostic (6.31e-2)" "unprognostic (1.59e-2)" "unprognostic (1.61e-1)" "unprognostic (6.40e-4)" "unprognostic (3.34e-3)" "unprognostic (2.63e-1)" "unprognostic (1.28e-2)" "unprognostic (2.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-2)" "unprognostic (8.95e-2)" SOWAHA ANKRD43 ENSG00000198944 "Sosondowah ankyrin repeat domain family member A" Q2M3V2 5 132813302-132816786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 154.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 24.8;Horizontal cells: 40.9;Intestinal goblet cells: 17.1;Muller glia cells: 25.5;Paneth cells: 21.2;Proximal enterocytes: 91.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.9" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 80.2" HPA064621 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" "HPA064621: AB_2685302" "unprognostic (1.59e-1)" "unprognostic (5.58e-2)" "unprognostic (3.75e-3)" "unprognostic (5.34e-3)" "unprognostic (8.28e-2)" "unprognostic (3.05e-3)" "unprognostic (1.18e-1)" "unprognostic (5.99e-2)" "unprognostic (1.27e-1)" "unprognostic (2.65e-2)" "prognostic favorable (4.03e-4)" "unprognostic (3.92e-2)" "prognostic favorable (9.38e-5)" "unprognostic (4.36e-1)" "unprognostic (3.00e-1)" "unprognostic (2.53e-3)" "unprognostic (1.42e-1)" TENT5A "C6orf37, FAM46A, FLJ20037" ENSG00000112773 "Terminal nucleotidyltransferase 5A" Q96IP4 6 81491439-81752774 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 223.3;salivary gland: 101.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 285.9;Proximal enterocytes: 279.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA051067, HPA067140" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 75: Serous glandular cells - Salivary secretion" 3 Nucleoplasm Cytosol "HPA051067: , HPA067140: AB_2685788" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (5.39e-2)" "unprognostic (1.12e-1)" "unprognostic (2.86e-2)" "unprognostic (2.62e-3)" "unprognostic (5.93e-2)" "unprognostic (2.48e-2)" "unprognostic (2.53e-1)" "unprognostic (1.03e-1)" "unprognostic (1.40e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (7.18e-2)" "unprognostic (6.38e-2)" "unprognostic (9.25e-2)" "unprognostic (9.66e-2)" TRPV3 VRL3 ENSG00000167723 "Transient receptor potential cation channel subfamily V member 3" Q8NET8 17 3510502-3557812 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, FDA approved drug targets, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.1;skeletal muscle: 1.5;skin 1: 4.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 13.2;Plasma cells: 14.2;Proximal enterocytes: 21.8;Schwann cells: 15.1;Skeletal myocytes: 8.8;Suprabasal keratinocytes: 13.4" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069550 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane" "Centrosome, Cytosol" "HPA069550: AB_2686149" "unprognostic (1.84e-4)" "unprognostic (2.25e-1)" "unprognostic (5.22e-2)" "unprognostic (3.92e-4)" "unprognostic (4.87e-3)" "unprognostic (2.96e-2)" "unprognostic (6.66e-2)" "unprognostic (4.88e-2)" "unprognostic (7.02e-2)" "unprognostic (2.68e-1)" "unprognostic (4.88e-2)" "unprognostic (3.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (8.64e-2)" "unprognostic (2.93e-2)" VDR "NR1I1, PPP1R163" ENSG00000111424 "Vitamin D receptor" P11473 12 47841537-47943048 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 228.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.5;monocytes: 89.1;Proximal enterocytes: 81.2;Schwann cells: 88.9;Undifferentiated cells: 56.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "classical monocyte: 3.5;eosinophil: 1.9;intermediate monocyte: 6.5;myeloid DC: 5.1;neutrophil: 6.6;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 8 "dendritic cells: 5.1;granulocytes: 6.6;monocytes: 6.7" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Region enhanced" "Detected in single" "olfactory bulb: 2.1" "Region enhanced" "Detected in some" "spinal cord: 5.8" "CAB004617, HPA047740, HPA072102" Supported "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 28: Dendritic cells - Antigen presentation" 11 Nucleoplasm "Intermediate filaments, Cytosol" "CAB004617: AB_628040, HPA047740: AB_2680142, HPA072102: " "unprognostic (1.11e-2)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (7.59e-3)" "unprognostic (3.33e-3)" "unprognostic (2.74e-2)" "unprognostic (4.78e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (6.72e-2)" "prognostic favorable (4.89e-6)" "unprognostic (1.46e-1)" "unprognostic (8.76e-2)" "unprognostic (3.28e-1)" "unprognostic (3.82e-2)" ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, p-170, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503017-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 98.7;intestine: 68.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 101.1;Microglial cells: 544.8;Proximal enterocytes: 247.2" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 27.2;NK-cell: 17.9" "Group enriched" "Detected in many" 9 "NK-cells: 17.9;T-cells: 27.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 26.0;liver cancer: 17.4" "Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001716, HPA002199, HPA074614" Enhanced Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 70: DU4475 - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane" "CAB001716: , HPA002199: AB_1844428, HPA074614: " "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favorable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 22.4;liver: 45.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 19.1;Hepatocytes: 46.7;Proximal enterocytes: 23.3;Proximal tubular cells: 45.4" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "classical monocyte: 3.9" "Lineage enriched" "Detected in single" 5 "monocytes: 3.9" "Cancer enhanced" "Detected in many" "liver cancer: 9.2" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 3: Choroid plexus - Cilium" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" ABCD1 "adrenoleukodystrophy, ALD, ALDP, AMN" ENSG00000101986 "ATP binding cassette subfamily D member 1" P33897 X 153724856-153744755 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 35.9;Sertoli cells: 29.9;Syncytiotrophoblasts: 26.5" "Cancer enhanced" "Detected in all" "melanoma: 36.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035214 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 18: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA035214: " "unprognostic (1.90e-2)" "unprognostic (3.79e-2)" "unprognostic (2.19e-3)" "unprognostic (5.57e-3)" "unprognostic (8.81e-3)" "unprognostic (1.54e-1)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (6.14e-3)" "unprognostic (3.40e-2)" "unprognostic (1.41e-1)" "unprognostic (6.17e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.57e-1)" "unprognostic (4.23e-2)" ABCG2 "ABCP, BCRP, CD338, EST157481, MXR" ENSG00000118777 "ATP binding cassette subfamily G member 2 (Junior blood group)" Q9UNQ0 4 88090150-88231628 "Cancer-related genes, CD markers, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 85.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 198.2;Distal enterocytes: 98.5;Extravillous trophoblasts: 89.8;Hofbauer cells: 125.1;Microglial cells: 177.1;Proximal enterocytes: 212.5" "Cancer enhanced" "Detected in many" "glioma: 9.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037299, HPA054719" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "Plasma membrane" Nucleoplasm "CAB037299: AB_476804, HPA054719: " "unprognostic (5.04e-1)" "unprognostic (3.05e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-1)" "unprognostic (1.01e-3)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.14e-2)" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (4.52e-2)" "unprognostic (1.67e-3)" "unprognostic (8.82e-3)" "unprognostic (7.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.92e-1)" ABHD14A-ACY1 ENSG00000114786 "ABHD14A-ACY1 readthrough" 3 51974706-51989183 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Hepatocytes: 14.5;Proximal enterocytes: 43.5;Proximal tubular cells: 17.2;Rod photoreceptor cells: 13.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA036174, HPA036175, HPA038153, HPA071834" Approved Supported Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 38: Proximal tubular cells - Transmembrane transport" Vesicles "HPA036174: AB_2674988, HPA036175: AB_2674989, HPA038153: AB_2675868, HPA071834: " "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "unprognostic (4.90e-2)" "unprognostic (7.22e-3)" "unprognostic (3.83e-2)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (6.23e-2)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (1.29e-2)" "unprognostic (9.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (7.11e-4)" ABHD14B "CIB, MGC15429" ENSG00000114779 "Abhydrolase domain containing 14B" Q96IU4 3 51968510-51983409 "Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 322.3;Proximal tubular cells: 234.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036444, HPA036642" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA 2100000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoplasm, Nucleoli" Cytosol "HPA036444: AB_10672221, HPA036642: AB_10672225" "unprognostic (8.97e-2)" "prognostic favorable (6.92e-5)" "unprognostic (1.84e-1)" "prognostic favorable (5.42e-5)" "unprognostic (1.07e-1)" "unprognostic (2.21e-2)" "unprognostic (2.06e-3)" "unprognostic (1.35e-3)" "unprognostic (3.95e-1)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (2.95e-2)" "prognostic favorable (2.93e-5)" "unprognostic (1.16e-1)" "unprognostic (3.55e-1)" "unprognostic (9.70e-2)" "unprognostic (3.70e-2)" ABHD6 ENSG00000163686 "Abhydrolase domain containing 6, acylglycerol lipase" Q9BV23 3 58237532-58295693 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 62.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 53.2;Oligodendrocytes: 82.5;Proximal enterocytes: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bone cancer: 53.5" "Skin - Keratinocyte (other), Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017283, HPA073225" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" 4 Vesicles Nucleoplasm "HPA017283: AB_1844452, HPA073225: AB_2686583" "unprognostic (4.20e-2)" "unprognostic (7.92e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.35e-2)" "unprognostic (1.16e-2)" "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (1.15e-2)" "unprognostic (9.54e-2)" "unprognostic (1.11e-3)" "unprognostic (1.34e-2)" "unprognostic (1.94e-1)" "prognostic favorable (1.11e-11)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (2.72e-1)" "unprognostic (6.31e-2)" ABO "A3GALNT, A3GALT1" ENSG00000175164 "ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase" 9 133233278-133276024 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 12.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 89.9;Enteroendocrine cells: 72.7;Intestinal goblet cells: 83.7;Proximal enterocytes: 189.2;Undifferentiated cells: 66.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.1;naive B-cell: 2.1" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Gallbladder cancer: 91.2" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 45: Intestine - Digestion" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (2.78e-3)" "unprognostic (2.56e-3)" "unprognostic (1.38e-1)" "unprognostic (1.87e-3)" "unprognostic (1.39e-1)" "unprognostic (3.10e-2)" "unprognostic (1.84e-3)" "unprognostic (1.30e-1)" "unprognostic (1.69e-2)" "unprognostic (8.51e-2)" "unprognostic (9.30e-3)" "unprognostic (7.23e-2)" "unprognostic (2.67e-2)" "unprognostic (4.57e-3)" "unprognostic (1.50e-1)" "unprognostic (2.34e-1)" "unprognostic (9.04e-2)" ACADS "ACAD3, SCAD" ENSG00000122971 "Acyl-CoA dehydrogenase short chain" P16219 12 120725774-120740008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 239.5;skeletal muscle: 152.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 338.4;Hepatocytes: 197.4;Proximal enterocytes: 428.7;Undifferentiated cells: 136.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004799, CAB019284, HPA022271" Enhanced Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 83: Liver - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Mitochondria "CAB019284: , HPA004799: AB_1844471, HPA022271: AB_1844472" "unprognostic (7.14e-2)" "unprognostic (3.03e-3)" "unprognostic (8.15e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.11e-3)" "unprognostic (5.75e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.14e-1)" "unprognostic (2.69e-2)" "unprognostic (4.04e-2)" "prognostic favorable (3.33e-6)" "unprognostic (1.23e-2)" "unprognostic (1.81e-1)" "unprognostic (1.21e-1)" "prognostic favorable (6.34e-5)" ACBD4 FLJ13322 ENSG00000181513 "Acyl-CoA binding domain containing 4" Q8NC06 17 45132600-45144181 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 90.7" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051772 Approved Approved Nucleoplasm,Vesicles Yes No "Cluster 24: Non-specific - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoplasm, Vesicles" "HPA051772: AB_2681603" "unprognostic (1.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.59e-2)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (1.60e-2)" "prognostic favorable (4.76e-4)" "unprognostic (2.27e-2)" "unprognostic (9.06e-2)" "unprognostic (4.86e-2)" "prognostic favorable (4.64e-4)" "unprognostic (8.24e-2)" "unprognostic (2.04e-3)" "unprognostic (1.97e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.53e-4)" ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597270-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 17.0;Ciliated cells: 12.9;Exocrine glandular cells: 9.5;Fibroblasts: 17.8;Gastric mucus-secreting cells: 8.3;Proximal enterocytes: 20.0" "Cancer enhanced" "Detected in many" "stomach cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 4.4" "Thyroid - Fibroblasts" "Group enriched" "Detected in some" 7 "cerebellum: 4.7;pons and medulla: 1.5" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria NA NA "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Vesicles, Mitochondria" "HPA054926: " "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-2)" "unprognostic (8.27e-2)" "unprognostic (5.17e-2)" "unprognostic (4.55e-3)" "unprognostic (8.93e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (4.20e-3)" "unprognostic (1.03e-3)" "unprognostic (2.69e-3)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 549.2;skeletal muscle: 637.1;tongue: 669.0" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 14: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" ACOT11 "BFIT, BFIT1, KIAA0707, STARD14, THEA, THEM1" ENSG00000162390 "Acyl-CoA thioesterase 11" Q8WXI4 1 54542257-54639192 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.2" "Cell type enhanced" "Detected in many" "Astrocytes: 127.9;Distal enterocytes: 67.0;Late spermatids: 151.8;Proximal enterocytes: 95.3;Skeletal myocytes: 87.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041047 Enhanced Supported Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Late spermatids - Spermatogenesis" Cytosol "HPA041047: AB_2677273" "unprognostic (9.73e-2)" "unprognostic (1.28e-1)" "prognostic favorable (9.37e-4)" "unprognostic (3.61e-4)" "unprognostic (5.42e-2)" "unprognostic (1.94e-1)" "unprognostic (2.20e-3)" "unprognostic (5.12e-4)" "unprognostic (1.05e-1)" "unprognostic (2.84e-2)" "unprognostic (9.60e-2)" "unprognostic (1.02e-1)" "prognostic favorable (3.07e-8)" "unprognostic (5.89e-2)" "unprognostic (1.08e-1)" "unprognostic (3.83e-2)" "unprognostic (8.49e-3)" ACOT4 "FLJ31235, PTE-Ib, PTE2B" ENSG00000177465 "Acyl-CoA thioesterase 4" Q8N9L9 14 73591873-73595766 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.4;liver: 16.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 29.9;Oocytes: 20.6;Proximal enterocytes: 19.2;Proximal tubular cells: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 18.6;breast cancer: 15.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Skin - Sebaceous gland cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA000779 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA000779: AB_1078093" "unprognostic (2.29e-3)" "unprognostic (2.53e-3)" "unprognostic (2.30e-1)" "unprognostic (2.29e-3)" "unprognostic (1.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-2)" "unprognostic (3.10e-2)" "unprognostic (1.72e-2)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.77e-4)" "unprognostic (3.95e-1)" "prognostic favorable (8.43e-5)" "unprognostic (2.47e-1)" "unprognostic (1.92e-1)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6393767 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 141.6" "Cell type enhanced" "Detected in many" "granulocytes: 178.0;Late spermatids: 160.2;Proximal enterocytes: 177.8;Proximal tubular cells: 237.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "NK-cell: 40.3;plasmacytoid DC: 35.8" "Group enriched" "Detected in many" 5 "dendritic cells: 35.8;NK-cells: 40.3" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025735, HPA025762" Enhanced Supported Nucleoplasm,Cytosol No No 26000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 22: Proximal enterocytes - Digestion" 8 Cytosol Nucleoplasm "HPA025735: AB_1844523, HPA025762: AB_1844524" "unprognostic (3.94e-2)" "unprognostic (1.74e-1)" "unprognostic (7.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.10e-2)" "unprognostic (5.06e-2)" "prognostic unfavorable (2.31e-5)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.35e-2)" "unprognostic (4.05e-2)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.68e-2)" "unprognostic (1.45e-1)" "unprognostic (9.06e-2)" "unprognostic (3.72e-2)" ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 104.5;Late spermatids: 90.9;Proximal enterocytes: 103.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 5: Enterocytes - Absorption" 3 Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" ACOX1 PALMCOX ENSG00000161533 "Acyl-CoA oxidase 1" Q15067 17 75941507-75979177 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 117.5" "Cell type enhanced" "Detected in all" "Distal enterocytes: 156.1;Hepatocytes: 249.6;Proximal enterocytes: 212.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 61.8;neutrophil: 84.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 84.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021094, HPA021192, HPA021195, HPA028759" Approved Approved Nucleoli,Peroxisomes NA NA 96000 "Cluster 35: Neutrophils - Protein binding" "Cluster 83: Liver - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" Peroxisomes Nucleoli "CAB021094: AB_10261667, HPA021192: AB_1844527, HPA021195: AB_1844528, HPA028759: AB_10601352" "unprognostic (7.47e-2)" "unprognostic (3.69e-1)" "unprognostic (1.25e-3)" "unprognostic (1.36e-1)" "unprognostic (7.49e-2)" "unprognostic (8.14e-2)" "unprognostic (3.75e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "unprognostic (1.25e-1)" "unprognostic (3.38e-2)" "prognostic favorable (5.25e-7)" "unprognostic (3.39e-1)" "unprognostic (2.41e-2)" "unprognostic (1.72e-1)" "unprognostic (4.46e-2)" ACSF2 "ACSMW, FLJ20920" ENSG00000167107 "Acyl-CoA synthetase family member 2" Q96CM8 17 50426158-50474845 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 137.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 83.1;Distal enterocytes: 60.8;Proximal enterocytes: 62.6;Proximal tubular cells: 105.7;Syncytiotrophoblasts: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024693 Enhanced Uncertain Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 17 "Nucleoplasm, Microtubules, Cytosol" "HPA024693: AB_2671654" "unprognostic (1.40e-2)" "unprognostic (1.34e-1)" "unprognostic (2.58e-1)" "unprognostic (1.53e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (8.48e-2)" "unprognostic (1.14e-2)" "unprognostic (6.49e-2)" "unprognostic (7.83e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (2.45e-2)" "prognostic favorable (2.41e-4)" ACSF3 ENSG00000176715 "Acyl-CoA synthetase family member 3" Q4G176 16 89088375-89164121 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 55.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008322 Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 5: Enterocytes - Absorption" 4 Mitochondria Nucleoplasm "HPA008322: AB_1845294" "unprognostic (1.94e-1)" "unprognostic (3.35e-1)" "unprognostic (4.66e-2)" "unprognostic (1.56e-2)" "unprognostic (1.14e-1)" "unprognostic (7.87e-2)" "unprognostic (5.68e-2)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.96e-1)" "prognostic favorable (3.76e-5)" "unprognostic (3.36e-2)" "prognostic favorable (5.97e-6)" "unprognostic (2.33e-1)" "unprognostic (5.09e-1)" "unprognostic (3.67e-1)" "unprognostic (2.00e-3)" ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374116-112428379 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 218.8;intestine: 418.8;liver: 165.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 138.0;Glandular and luminal cells: 296.7;Proximal enterocytes: 460.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bile duct cancer: 97.2;colorectal cancer: 99.3" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Glandular & Luminal cells - Unknown function" 9 Mitochondria Nucleoplasm "CAB035986: AB_941506, CAB062546: AB_2665614, HPA007162: AB_2667761" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.45e-1)" "unprognostic (2.13e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.06e-2)" "unprognostic (4.18e-3)" "unprognostic (7.40e-2)" "unprognostic (5.25e-3)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (5.92e-3)" "unprognostic (1.08e-3)" ADAMTSL5 THSD6 ENSG00000185761 "ADAMTS like 5" 19 1505022-1513604 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 8.9;Leydig cells: 19.9;Peritubular cells: 17.9;Proximal enterocytes: 11.3;Sertoli cells: 10.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Skeletal muscle - Skeletal myocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044050 Approved "Golgi apparatus" "Secreted to extracellular matrix" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: Endometrial stromal cells - Transcription" "Golgi apparatus" "HPA044050: AB_10962625" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (5.85e-2)" "unprognostic (2.45e-1)" "unprognostic (1.10e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (1.77e-2)" "unprognostic (1.89e-1)" "unprognostic (2.79e-2)" "unprognostic (2.89e-3)" "unprognostic (1.52e-1)" "unprognostic (5.03e-2)" "unprognostic (1.18e-1)" "unprognostic (3.04e-2)" "unprognostic (1.44e-1)" "unprognostic (2.37e-3)" ADAP1 "CENTA1, GCS1L" ENSG00000105963 "ArfGAP with dual PH domains 1" O75689 7 897900-955407 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 128.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.0;Oocytes: 183.8;Paneth cells: 49.5;Proximal enterocytes: 46.1" "Cancer enhanced" "Detected in all" "colorectal cancer: 15.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "colorectal cancer: 123.4;Gastric cancer: 101.4" "Adipose subcutaneous - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007033, HPA012049" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 5 "Plasma membrane, Cytosol" "HPA007033: AB_1846529, HPA012049: AB_1846527" "unprognostic (2.45e-1)" "unprognostic (7.15e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (4.41e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (3.06e-1)" "unprognostic (9.10e-3)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (5.74e-2)" "unprognostic (1.69e-1)" "prognostic favorable (4.13e-5)" "unprognostic (5.88e-2)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-2)" ADCK5 FLJ35454 ENSG00000173137 "AarF domain containing kinase 5" Q3MIX3 8 144373101-144393242 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 55.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025692, HPA028679" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane, Cytosol" "HPA025692: AB_10599486, HPA028679: AB_10600226" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (8.96e-2)" "unprognostic (1.68e-2)" "unprognostic (1.00e-1)" "unprognostic (2.31e-3)" "unprognostic (6.45e-2)" "unprognostic (2.70e-1)" "unprognostic (4.25e-2)" "unprognostic (6.60e-2)" "unprognostic (2.03e-2)" "unprognostic (1.33e-3)" "unprognostic (1.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-1)" "unprognostic (2.90e-2)" ADIRF "AFRO, APM2, C10orf116" ENSG00000148671 "Adipogenesis regulatory factor" Q15847 10 86968432-86983934 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1195.0" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 2121.3;Proximal enterocytes: 11678.7;Smooth muscle cells: 3088.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.6;naive CD8 T-cell: 1.9" "Lineage enriched" "Detected in single" 8 "T-cells: 2.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 835.4" "Low region specificity" "Detected in all" HPA026810 Approved Supported Nucleoplasm,Cytosol NA NA 760000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "Nucleoplasm, Cytosol" "HPA026810: AB_2672003" ADM2 "AM2, FLJ21135" ENSG00000128165 "Adrenomedullin 2" Q7Z4H4 22 50481543-50486440 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.1;pancreas: 15.0;thyroid gland: 11.2" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 12.4;Intestinal goblet cells: 7.4;Plasma cells: 9.1;Proximal enterocytes: 5.8;Proximal tubular cells: 25.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Myeloma: 22.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" Hormone NA NA 61300 "Cluster 68: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 38: Proximal tubular cells - Transmembrane transport" "unprognostic (1.30e-2)" "unprognostic (4.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-1)" "unprognostic (3.15e-1)" "unprognostic (4.62e-3)" "unprognostic (7.26e-3)" "unprognostic (1.50e-1)" "unprognostic (3.44e-1)" "unprognostic (7.20e-2)" "unprognostic (9.41e-2)" "unprognostic (7.30e-3)" "unprognostic (1.17e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.06e-2)" ADTRP "AIG1L, C6orf105, dJ413H6.1" ENSG00000111863 "Androgen dependent TFPI regulating protein" Q96IZ2 6 11712054-11807046 "Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 100.6;intestine: 95.7;parathyroid gland: 89.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 99.6;Distal tubular cells: 76.8;Early spermatids: 132.7;Late spermatids: 185.1;Paneth cells: 58.0;Proximal enterocytes: 128.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 10 "choroid plexus: 79.3" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 14.8;T-reg: 13.6" "Lineage enriched" "Detected in many" 5 "T-cells: 14.8" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA048113 Uncertain Uncertain Nucleoli NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 5: Enterocytes - Absorption" 2 Nucleoli "HPA048113: AB_2680268" "unprognostic (6.82e-3)" "unprognostic (1.41e-1)" "unprognostic (1.58e-1)" "unprognostic (8.14e-3)" "unprognostic (3.04e-3)" "unprognostic (1.41e-2)" "unprognostic (4.00e-2)" "unprognostic (1.77e-1)" "unprognostic (1.85e-2)" "unprognostic (2.72e-1)" "unprognostic (5.41e-3)" "unprognostic (2.90e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (2.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.95e-2)" "unprognostic (1.26e-1)" AGPAT2 "BSCL, LPAAT-beta, LPLAT2" ENSG00000169692 "1-acylglycerol-3-phosphate O-acyltransferase 2" O15120 9 136673143-136687457 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 357.5;liver: 434.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 717.6;Late spermatids: 400.5;Paneth cells: 447.9;Proximal enterocytes: 1298.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA019544 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" "HPA019544: AB_1844646" "unprognostic (3.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (9.26e-2)" "unprognostic (1.50e-1)" "unprognostic (9.30e-3)" "unprognostic (5.06e-3)" "unprognostic (8.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (2.17e-1)" "unprognostic (5.61e-2)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-2)" "unprognostic (2.93e-1)" AGR3 "BCMP11, hAG-3, HAG3, PDIA18" ENSG00000173467 "Anterior gradient 3, protein disulphide isomerase family member" Q8TD06 7 16859412-16881987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 217.5;intestine: 230.7;lung: 147.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 316.3;Ciliated cells: 1021.0;Distal enterocytes: 365.9;Enteroendocrine cells: 327.6;Intestinal goblet cells: 689.4;Ionocytes: 347.5;Paneth cells: 692.8;Proximal enterocytes: 1057.5;Undifferentiated cells: 404.6" "Cancer enhanced" "Detected in many" "breast cancer: 104.5" "Region enhanced" "Detected in some" "midbrain: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "breast cancer: 51.8;colorectal cancer: 65.3;Gastric cancer: 151.5" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enriched" "Detected in some" 5 "olfactory bulb: 4.6" HPA053942 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 67000 "Cluster 45: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 21 "Endoplasmic reticulum" Vesicles "HPA053942: AB_2682317" "unprognostic (2.18e-2)" "unprognostic (2.02e-1)" "unprognostic (2.13e-1)" "unprognostic (9.59e-2)" "unprognostic (3.32e-3)" "unprognostic (3.08e-2)" "unprognostic (1.49e-1)" "unprognostic (1.46e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-1)" "unprognostic (8.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.96e-1)" "unprognostic (6.66e-2)" "unprognostic (1.57e-1)" AIG1 "AIG-1, dJ95L4.1, FLJ10485" ENSG00000146416 "Androgen induced 1" Q9NVV5 6 143060496-143341058 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 228.2" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 245.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060766 Approved Uncertain "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" 1 "Golgi apparatus" "HPA060766: AB_2684356" "unprognostic (2.70e-2)" "prognostic unfavorable (3.26e-6)" "unprognostic (4.27e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.34e-2)" "prognostic unfavorable (3.25e-7)" "unprognostic (1.91e-2)" "unprognostic (8.75e-3)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" "unprognostic (2.74e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (9.11e-2)" "unprognostic (2.75e-1)" AKR1A1 "ALR, DD3" ENSG00000117448 "Aldo-keto reductase family 1 member A1" P14550 1 45550543-45570049 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 926.7;Proximal tubular cells: 1034.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006246, HPA017919, HPA019649, HPA027734" Approved Supported Nucleoplasm,Cytosol NA NA 7600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 22: Proximal enterocytes - Digestion" 3 Cytosol Nucleoplasm "CAB006246: AB_425840, HPA017919: AB_1844695, HPA019649: AB_1844696, HPA027734: AB_10600976" "unprognostic (1.73e-1)" "prognostic favorable (2.66e-6)" "unprognostic (4.03e-1)" "prognostic favorable (2.92e-4)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (1.31e-3)" "unprognostic (2.52e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (8.43e-2)" "unprognostic (4.51e-2)" "unprognostic (1.56e-2)" "unprognostic (2.46e-1)" "unprognostic (2.89e-2)" "unprognostic (4.57e-2)" AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 218.2;intestine: 597.0;stomach 1: 421.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 383.9;Cholangiocytes: 194.6;Distal enterocytes: 223.5;Gastric mucus-secreting cells: 493.5;Proximal enterocytes: 367.6;Suprabasal keratinocytes: 535.7" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Gallbladder cancer: 2714.5" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" Enzyme NA NA 67000000 "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" 2 Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 428.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 375.3;Cholangiocytes: 311.0;Exocrine glandular cells: 549.8;Hepatocytes: 451.0;Proximal enterocytes: 608.0;Proximal tubular cells: 497.6" "Cancer enhanced" "Detected in all" "liver cancer: 83.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.9;gdT-cell: 102.8" "Group enriched" "Detected in many" 4 "granulocytes: 244.9;T-cells: 102.8" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1748.7" "Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 19000000 "Cluster 41: Basophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: AB_476751, HPA068265: AB_2685966" "unprognostic (4.20e-3)" "unprognostic (2.70e-2)" "unprognostic (8.92e-2)" "unprognostic (1.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.41e-1)" "unprognostic (6.74e-2)" "unprognostic (5.08e-2)" "unprognostic (1.31e-1)" "unprognostic (4.33e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (4.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.79e-3)" "unprognostic (4.24e-3)" AKR7A2 AFAR ENSG00000053371 "Aldo-keto reductase family 7 member A2" O43488 1 19303965-19312144 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 290.8;Proximal tubular cells: 522.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "CAB032587, CAB032841, HPA064638" Enhanced Supported "Golgi apparatus,Cytosol" NA NA 950000 "Cluster 13: Non-specific - Mitochondria" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 4 Cytosol "Golgi apparatus" "CAB032587: AB_673379, CAB032841: AB_2224545, HPA064638: AB_2685307" "unprognostic (1.06e-1)" "unprognostic (3.48e-2)" "unprognostic (7.23e-2)" "unprognostic (5.76e-2)" "unprognostic (9.92e-2)" "unprognostic (1.09e-1)" "unprognostic (1.14e-2)" "unprognostic (3.14e-3)" "unprognostic (1.99e-1)" "unprognostic (2.50e-2)" "unprognostic (5.11e-2)" "unprognostic (7.11e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.72e-2)" "unprognostic (8.53e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (8.59e-4)" AKR7A3 ENSG00000162482 "Aldo-keto reductase family 7 member A3" O95154 1 19282573-19288770 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 241.7;liver: 150.8;pancreas: 280.1;stomach 1: 218.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 198.9;Gastric mucus-secreting cells: 346.7;Proximal enterocytes: 1214.3;Proximal tubular cells: 627.0" "Cancer enhanced" "Detected in many" "liver cancer: 36.8" "Region enriched" "Detected in all" 5 "choroid plexus: 35.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 16.8;colorectal cancer: 19.5;Gastric cancer: 18.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes" HPA064638 Supported "Golgi apparatus,Cytosol" NA NA 1900000 "Cluster 48: Stomach - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 5 Cytosol "Golgi apparatus" "HPA064638: AB_2685307" "unprognostic (7.78e-2)" "unprognostic (5.07e-2)" "unprognostic (6.08e-2)" "unprognostic (1.61e-1)" "unprognostic (1.10e-2)" "unprognostic (8.84e-2)" "unprognostic (3.85e-3)" "unprognostic (7.70e-3)" "unprognostic (2.72e-1)" "unprognostic (2.50e-2)" "unprognostic (1.17e-1)" "unprognostic (2.98e-1)" "prognostic favorable (8.80e-7)" "unprognostic (4.53e-2)" "unprognostic (5.58e-2)" "unprognostic (2.85e-1)" "unprognostic (2.35e-1)" ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605941-95656711 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 116.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.5;Proximal enterocytes: 67.2;Serous glandular cells: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008333, HPA012604" Approved Enhanced Mitochondria NA NA 48000 "Cluster 24: Non-specific - Transcription" "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 75: Serous glandular cells - Salivary secretion" 4 Mitochondria "HPA008333: AB_1078125, HPA012604: AB_1844721" "unprognostic (5.97e-3)" "unprognostic (2.08e-2)" "unprognostic (5.75e-2)" "prognostic favorable (4.20e-4)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (8.30e-3)" "unprognostic (7.08e-2)" "unprognostic (4.06e-2)" "unprognostic (8.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.60e-9)" "unprognostic (1.02e-3)" "unprognostic (6.57e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" AMT "GCST, NKH" ENSG00000145020 Aminomethyltransferase P48728 3 49416778-49422685 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 47.9" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 12.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 7.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "liver cancer: 9.7;testis cancer: 8.3" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005566 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 61: Plasma cells - Immunoglobulins & histones" Mitochondria Nucleoplasm "HPA005566: AB_1844811" "unprognostic (2.10e-2)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (9.14e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (2.81e-1)" "unprognostic (2.17e-3)" "unprognostic (1.94e-1)" "unprognostic (3.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.88e-1)" "prognostic favorable (3.90e-8)" "unprognostic (4.40e-1)" "unprognostic (1.91e-1)" "unprognostic (3.60e-1)" "unprognostic (1.98e-3)" ANKRD9 ENSG00000156381 "Ankyrin repeat domain 9" Q96BM1 14 102501767-102509799 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 108.5;skeletal muscle: 149.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 185.7;Distal tubular cells: 101.4;Early spermatids: 146.0;granulocytes: 128.0;Proximal enterocytes: 128.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055985 Uncertain NA NA "Cluster 23: Non-specific - Cellular respiration" "Cluster 18: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" "HPA055985: AB_2682996" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (3.05e-2)" "unprognostic (1.26e-2)" "unprognostic (7.76e-2)" "unprognostic (7.31e-3)" "unprognostic (6.78e-2)" "unprognostic (3.97e-2)" "unprognostic (3.35e-1)" "unprognostic (2.99e-1)" "unprognostic (3.68e-1)" "unprognostic (1.17e-1)" "prognostic favorable (1.17e-7)" "unprognostic (3.89e-1)" "unprognostic (4.74e-1)" "unprognostic (1.32e-2)" "unprognostic (1.15e-1)" ANO9 "PIG5, TMEM16J, TP53I5" ENSG00000185101 "Anoctamin 9" A1A5B4 11 417933-442011 "Predicted membrane proteins, Transporters" "Lipid metabolism, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.3;skin 1: 27.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 67.5;Intestinal goblet cells: 47.0;Paneth cells: 31.3;Proximal enterocytes: 75.1;Undifferentiated cells: 32.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 26.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 48 "B-cells: 2.1;NK-cells: 4.1;T-cells: 8.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.4" "Adipose subcutaneous - T-cells, Liver - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039948, HPA040112" Approved Uncertain "Golgi apparatus" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Golgi apparatus" "HPA039948: AB_2676765, HPA040112: " "unprognostic (3.62e-3)" "unprognostic (2.83e-2)" "unprognostic (4.68e-2)" "unprognostic (1.62e-1)" "unprognostic (1.41e-2)" "unprognostic (8.93e-2)" "unprognostic (6.98e-2)" "unprognostic (8.94e-3)" "unprognostic (1.39e-1)" "unprognostic (2.28e-3)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (1.91e-2)" "unprognostic (1.18e-2)" "unprognostic (2.08e-1)" "unprognostic (3.92e-1)" "prognostic favorable (8.81e-4)" ANXA13 ANX13 ENSG00000104537 "Annexin A13" P27216 8 123680794-123737402 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 139.6;intestine: 285.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 54.4;Cholangiocytes: 171.7;Enteroendocrine cells: 41.5;Intestinal goblet cells: 145.0;Paneth cells: 55.5;Proximal enterocytes: 129.5;Undifferentiated cells: 47.9" "Group enriched" "Detected in many" 13 "colorectal cancer: 7.8;liver cancer: 8.5;pancreatic cancer: 6.1;renal cancer: 7.0;stomach cancer: 7.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 18.8;Gastric cancer: 33.6;Kidney cancer: 22.6" "Lung - Respiratory ciliated cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018535, HPA019569, HPA019650, CAB025135" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" "Plasma membrane" Nucleoplasm "CAB025135: , HPA018535: AB_1844854, HPA019569: AB_1844855, HPA019650: AB_1844856" "unprognostic (6.47e-3)" "unprognostic (1.95e-1)" "unprognostic (3.50e-2)" "unprognostic (1.83e-1)" "unprognostic (5.66e-2)" "unprognostic (4.05e-2)" "unprognostic (5.48e-2)" "unprognostic (2.86e-3)" "unprognostic (2.06e-1)" "unprognostic (9.11e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.49e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (4.79e-2)" ANXA4 ANX4 ENSG00000196975 "Annexin A4" P09525 2 69644425-69827112 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 551.0;pancreas: 345.6" "Cell type enhanced" "Detected in all" "Cholangiocytes: 2319.9;Ductal cells: 1498.9;Proximal enterocytes: 674.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 8 "choroid plexus: 85.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005076, HPA007393, CAB017560" Enhanced Approved Cytosol NA NA 550000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 8 Cytosol "CAB005076: AB_630869, CAB017560: AB_2227370, HPA007393: AB_1078168" "prognostic unfavorable (8.55e-4)" "unprognostic (3.37e-2)" "unprognostic (4.82e-2)" "unprognostic (9.03e-2)" "unprognostic (1.62e-3)" "unprognostic (1.66e-1)" "unprognostic (3.57e-1)" "unprognostic (3.21e-1)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (7.23e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.79e-1)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (3.97e-2)" AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 165.2;Proximal enterocytes: 170.4;Proximal tubular cells: 352.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA054999, HPA077258" Supported Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 Vesicles Cytosol "HPA054999: AB_2682666, HPA077258: " "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" AP1S1 "AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2" ENSG00000106367 "Adaptor related protein complex 1 subunit sigma 1" P61966 7 101154456-101161596 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Ichthyosis, Intellectual disability, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 105.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 221.3;Proximal enterocytes: 242.7;Proximal tubular cells: 297.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060945 Supported Supported "Golgi apparatus,Vesicles" NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 "Golgi apparatus, Vesicles" "HPA060945: AB_2684393" "unprognostic (1.98e-2)" "unprognostic (5.41e-3)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-3)" "unprognostic (8.70e-3)" "unprognostic (7.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.76e-1)" "unprognostic (7.79e-2)" "unprognostic (1.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" APPL2 "DIP13B, FLJ10659" ENSG00000136044 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2" Q8NEU8 12 105173297-105236203 "Disease related genes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 110.3;Microglial cells: 107.4;Proximal enterocytes: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039688, HPA043925, HPA079223" Approved Approved Vesicles,Cytosol NA NA 45000 "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 5: Enterocytes - Absorption" 13 Vesicles Cytosol "HPA039688: AB_2676626, HPA043925: AB_2678733, HPA079223: " "unprognostic (3.46e-1)" "unprognostic (4.21e-1)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.54e-2)" "unprognostic (2.41e-2)" "unprognostic (6.66e-3)" "unprognostic (8.43e-2)" "unprognostic (5.50e-2)" "unprognostic (5.71e-3)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "prognostic favorable (7.65e-4)" "unprognostic (1.87e-1)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" "unprognostic (9.32e-2)" AQP11 AQPX1 ENSG00000178301 "Aquaporin 11" Q8NBQ7 11 77589391-77610356 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 27.8;liver: 15.6" "Cell type enhanced" "Detected in many" "Early spermatids: 46.7;Hepatocytes: 37.4;Late spermatids: 63.7;Proximal enterocytes: 33.3;Spermatocytes: 50.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077460 Supported "Vesicles,Plasma membrane" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "Plasma membrane" Vesicles "HPA077460: " "unprognostic (4.95e-2)" "unprognostic (7.61e-2)" "unprognostic (2.15e-2)" "unprognostic (9.62e-5)" "unprognostic (2.42e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-1)" "unprognostic (3.48e-2)" "unprognostic (2.65e-1)" "prognostic favorable (9.89e-4)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.73e-2)" "unprognostic (2.44e-1)" "unprognostic (6.46e-2)" "unprognostic (1.66e-3)" AQP7 "AQP7L, AQP9, AQPap" ENSG00000165269 "Aquaporin 7" O14520 9 33383179-33402682 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 205.9;breast: 101.5;heart muscle: 105.1" "Cell type enhanced" "Detected in many" "Adipocytes: 105.7;Cardiomyocytes: 87.0;Early spermatids: 152.5;Proximal enterocytes: 143.0;Proximal tubular cells: 53.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 1 "unprognostic (3.25e-2)" "unprognostic (3.81e-3)" "unprognostic (1.25e-5)" "unprognostic (7.22e-3)" "unprognostic (1.50e-1)" "unprognostic (3.32e-1)" "unprognostic (4.67e-2)" "unprognostic (3.06e-2)" "unprognostic (9.99e-2)" "unprognostic (4.65e-2)" "unprognostic (8.56e-4)" "unprognostic (1.21e-1)" "prognostic favorable (9.21e-8)" "unprognostic (2.42e-1)" "unprognostic (1.28e-1)" "unprognostic (1.61e-1)" "unprognostic (2.12e-3)" ARHGEF16 "GEF16, NBR" ENSG00000130762 "Rho guanine nucleotide exchange factor 16" Q5VV41 1 3454665-3481113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.4;Extravillous trophoblasts: 65.7;Gastric mucus-secreting cells: 56.6;Intestinal goblet cells: 57.1;Paneth cells: 48.6;Proximal enterocytes: 64.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Region enhanced" "Detected in many" "olfactory bulb: 4.7" "Low region specificity" "Detected in many" HPA010609 Approved NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" 8 "HPA010609: AB_1845004" "unprognostic (1.28e-1)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (4.31e-1)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (2.65e-1)" "unprognostic (5.59e-2)" "unprognostic (1.79e-2)" "unprognostic (5.39e-2)" "unprognostic (9.16e-2)" "prognostic favorable (1.24e-10)" "unprognostic (6.46e-2)" "unprognostic (2.86e-1)" "unprognostic (1.71e-2)" "unprognostic (3.29e-2)" ARSA ASA ENSG00000100299 "Arylsulfatase A" P15289 22 50622754-50628173 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 125.6;Plasma cells: 119.7;Proximal enterocytes: 95.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005554, CAB025183" Enhanced Uncertain "Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme NA NA 5600000 "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 66: Non-specific - Mitochondria" "Cluster 77: Plasma cells - Protein processing" 11 "Golgi apparatus" Cytosol "CAB025183: , HPA005554: AB_1078220" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (4.07e-2)" "prognostic favorable (2.96e-5)" "unprognostic (4.66e-2)" "unprognostic (4.40e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-2)" "unprognostic (2.16e-1)" "unprognostic (4.47e-2)" "unprognostic (2.76e-1)" "unprognostic (9.90e-2)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (7.73e-3)" ARSL "ARSE, CDPX, CDPX1" ENSG00000157399 "Arylsulfatase L" P51690 X 2934045-2968475 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 35.3;liver: 88.3;pancreas: 101.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 29.6;Ductal cells: 29.7;Enteroendocrine cells: 41.0;Hepatocytes: 64.9;Paneth cells: 46.8;Proximal enterocytes: 47.7;Proximal tubular cells: 77.6;Undifferentiated cells: 56.9" "Cancer enhanced" "Detected in many" "liver cancer: 34.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 30.8;liver cancer: 33.4" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "HPA060518, HPA070651" Approved Supported "Golgi apparatus" NA NA "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" "Golgi apparatus" "HPA060518: AB_2684301, HPA070651: AB_2732160" "unprognostic (2.07e-1)" "unprognostic (6.60e-3)" "prognostic favorable (8.95e-4)" "unprognostic (8.74e-3)" "unprognostic (1.14e-3)" "unprognostic (3.48e-2)" "unprognostic (2.38e-1)" "unprognostic (8.27e-2)" "unprognostic (5.45e-2)" "unprognostic (2.25e-1)" "unprognostic (2.27e-1)" "unprognostic (2.37e-1)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (1.28e-1)" "unprognostic (5.94e-2)" "unprognostic (4.76e-2)" ASB13 "FLJ13134, MGC19879" ENSG00000196372 "Ankyrin repeat and SOCS box containing 13" Q8WXK3 10 5638867-5666595 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.9;Cone photoreceptor cells: 54.4;Hepatocytes: 52.2;Proximal enterocytes: 38.9;Proximal tubular cells: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 13.6;monocytes: 12.9;T-cells: 4.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048293, HPA061742" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 43: Hepatocytes - Metabolism" 10 "Nucleoplasm, Golgi apparatus" "HPA048293: AB_2680344, HPA061742: AB_2684599" "unprognostic (3.64e-2)" "unprognostic (3.60e-1)" "unprognostic (7.39e-2)" "unprognostic (2.21e-2)" "unprognostic (4.83e-2)" "unprognostic (2.77e-2)" "unprognostic (1.74e-1)" "unprognostic (2.47e-1)" "unprognostic (2.90e-2)" "unprognostic (2.87e-1)" "unprognostic (6.93e-2)" "unprognostic (3.42e-2)" "unprognostic (4.58e-3)" "unprognostic (1.16e-2)" "unprognostic (3.03e-1)" "unprognostic (2.87e-2)" "unprognostic (1.40e-2)" ASPA "ACY2, ASP" ENSG00000108381 Aspartoacylase P45381 17 3472374-3503405 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.9;kidney: 36.8" "Cell type enhanced" "Detected in many" "Leydig cells: 48.3;Melanocytes: 77.3;Oligodendrocytes: 201.9;Peritubular cells: 47.4;Proximal enterocytes: 35.0;Proximal tubular cells: 60.7;Schwann cells: 52.0" "Cancer enhanced" "Detected in some" "renal cancer: 7.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Colon - Enteric glia cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022142, HPA022145" Enhanced Supported Cytosol NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" 8 Cytosol "HPA022142: AB_1845102, HPA022145: AB_1845103" "unprognostic (4.42e-2)" "unprognostic (4.79e-2)" "unprognostic (2.02e-2)" "unprognostic (2.79e-3)" "unprognostic (4.36e-2)" "unprognostic (5.01e-1)" "unprognostic (1.08e-3)" "unprognostic (3.57e-1)" "unprognostic (4.17e-1)" "unprognostic (3.43e-1)" "unprognostic (5.27e-2)" "unprognostic (6.27e-2)" "unprognostic (1.25e-1)" "unprognostic (7.07e-4)" "unprognostic (2.77e-1)" "unprognostic (4.68e-1)" "unprognostic (1.49e-1)" ATG4D "APG4-D, APG4D, AUTL4" ENSG00000130734 "Autophagy related 4D cysteine peptidase" Q86TL0 19 10543895-10553418 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 114.4;Early spermatids: 114.6;Proximal enterocytes: 104.7;Spermatocytes: 83.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA067683 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" "Nucleoplasm, Mitochondria" "HPA067683: AB_2685886" "unprognostic (2.85e-1)" "prognostic favorable (3.18e-5)" "unprognostic (2.73e-1)" "unprognostic (3.67e-1)" "unprognostic (2.18e-1)" "unprognostic (1.15e-2)" "unprognostic (3.52e-2)" "unprognostic (1.23e-1)" "unprognostic (4.28e-2)" "unprognostic (7.30e-2)" "prognostic favorable (9.95e-4)" "unprognostic (1.52e-1)" "prognostic favorable (2.39e-7)" "prognostic favorable (5.03e-4)" "unprognostic (3.78e-2)" "unprognostic (2.29e-1)" "unprognostic (3.18e-3)" ATP1A1 ENSG00000163399 "ATPase Na+/K+ transporting subunit alpha 1" P05023 1 116372668-116410261 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" Translocase "Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Intellectual disability, Neurodegeneration, Neuropathy, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1433.4" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1705.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018702, CAB069993" Enhanced NA NA 420000 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 70: DU4475 - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "CAB018702: AB_626713, CAB069993: AB_2060979" "unprognostic (6.18e-2)" "unprognostic (2.18e-1)" "unprognostic (6.91e-2)" "unprognostic (1.42e-2)" "unprognostic (6.80e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (1.80e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.61e-2)" "unprognostic (1.65e-1)" "prognostic favorable (8.98e-8)" "unprognostic (4.75e-2)" "unprognostic (1.17e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (4.01e-4)" ATP5F1D ATP5D ENSG00000099624 "ATP synthase F1 subunit delta" P30049 19 1241746-1244825 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 777.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 2198.3;Proximal enterocytes: 1959.3;Proximal tubular cells: 1801.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002865 Approved NA NA 160000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 7 "HPA002865: AB_1078244" "unprognostic (4.80e-2)" "unprognostic (9.34e-2)" "unprognostic (7.77e-2)" "prognostic favorable (1.23e-4)" "unprognostic (1.64e-2)" "unprognostic (1.95e-1)" "unprognostic (4.63e-2)" "unprognostic (6.75e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-1)" "prognostic favorable (4.60e-4)" "unprognostic (6.95e-2)" "prognostic favorable (3.46e-5)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "unprognostic (3.74e-1)" "unprognostic (3.49e-2)" B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711358-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 20023.7;Proximal enterocytes: 18472.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA NA 1790000000 2100000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 11 "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" B3GNT3 "B3GN-T3, B3GNT-3, beta3Gn-T3, HP10328, TMEM3" ENSG00000179913 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3" Q9Y2A9 19 17794828-17813576 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.6;salivary gland: 30.4;stomach 1: 42.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 80.1;Cytotrophoblasts: 83.2;Distal enterocytes: 96.8;Intestinal goblet cells: 43.4;Paneth cells: 75.2;Proximal enterocytes: 58.0;Syncytiotrophoblasts: 70.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 64.9" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024298 Enhanced "Intracellular and membrane" Enzyme NA NA 74000 "Cluster 39: T-cells - T-cell receptor" "Cluster 45: Intestine - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA024298: AB_1845236" "unprognostic (1.10e-1)" "unprognostic (5.19e-2)" "unprognostic (1.84e-1)" "unprognostic (4.84e-3)" "unprognostic (1.10e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (3.26e-1)" "unprognostic (4.64e-2)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.91e-1)" "unprognostic (1.44e-2)" "unprognostic (7.38e-2)" "unprognostic (1.26e-1)" "unprognostic (7.10e-2)" "unprognostic (2.57e-2)" B3GNT8 "B3GALT7, beta3Gn-T8, BGALT15" ENSG00000177191 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8" Q7Z7M8 19 41425359-41428730 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 43.3;intestine: 19.2;vagina: 18.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 51.8;Distal enterocytes: 59.2;Intestinal goblet cells: 29.1;Paneth cells: 44.8;Proximal enterocytes: 63.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 117.8;eosinophil: 146.9;neutrophil: 198.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 198.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.3;Leukemia: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043669 Enhanced "Intracellular and membrane" Enzyme NA NA 57000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "HPA043669: AB_2678608" "unprognostic (6.89e-2)" "unprognostic (2.46e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (4.11e-4)" "unprognostic (6.44e-3)" "unprognostic (6.51e-3)" "unprognostic (1.84e-2)" "unprognostic (9.92e-3)" "unprognostic (7.30e-2)" "unprognostic (2.56e-2)" "prognostic favorable (9.31e-6)" "unprognostic (5.04e-2)" "unprognostic (2.62e-3)" "unprognostic (2.07e-1)" "unprognostic (6.16e-2)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" B4GALNT2 "Cad, GALGT2, Sda" ENSG00000167080 "Beta-1,4-N-acetyl-galactosaminyltransferase 2" Q8NHY0 17 49132460-49176840 "Disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.8;Distal enterocytes: 29.9;Enteroendocrine cells: 6.6;Glandular and luminal cells: 6.2;Intestinal goblet cells: 25.3;Proximal enterocytes: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Skin - Outer root sheath cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015721 Approved NA NA "Cluster 45: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" 2 "HPA015721: AB_1845245" "unprognostic (4.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.26e-3)" "unprognostic (2.03e-4)" "unprognostic (1.72e-2)" "unprognostic (2.62e-2)" "unprognostic (3.67e-2)" "unprognostic (7.67e-2)" "unprognostic (4.06e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.29e-5)" "unprognostic (3.53e-1)" "unprognostic (1.31e-1)" "unprognostic (7.81e-3)" "unprognostic (2.15e-1)" BAK1 "BAK, BCL2L7, CDN1" ENSG00000030110 "BCL2 antagonist/killer 1" Q16611 6 33572547-33580293 "Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 67.4;Proximal enterocytes: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005029 Enhanced NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 43: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 61: Plasma cells - Immunoglobulins & histones" 18 "CAB005029: AB_562051" "unprognostic (3.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (5.67e-2)" "unprognostic (6.58e-3)" "prognostic unfavorable (4.52e-4)" "prognostic unfavorable (5.64e-4)" "unprognostic (2.36e-1)" "unprognostic (1.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (6.07e-2)" "unprognostic (3.36e-2)" "unprognostic (1.20e-1)" "unprognostic (1.46e-1)" BATF2 MGC20410 ENSG00000168062 "Basic leucine zipper ATF-like transcription factor 2" Q8N1L9 11 64987945-64997018 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 18.9;Enteroendocrine cells: 13.2;Intestinal goblet cells: 8.6;Paneth cells: 10.1;Proximal enterocytes: 7.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 2.1;intermediate monocyte: 5.3;neutrophil: 7.4;non-classical monocyte: 2.8" "Group enriched" "Detected in many" 6 "granulocytes: 7.4;monocytes: 5.3" "Cancer enriched" "Detected in many" 5 "Myeloma: 29.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA062496 Approved Approved Nucleoli NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Enterocytes - Absorption" 10 Nucleoli "HPA062496: AB_2684783" "unprognostic (5.29e-2)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (4.59e-2)" "unprognostic (2.31e-2)" "unprognostic (6.11e-2)" "unprognostic (5.08e-2)" "unprognostic (6.92e-3)" "unprognostic (1.03e-1)" "prognostic favorable (9.39e-5)" "prognostic unfavorable (2.12e-4)" "unprognostic (1.28e-1)" "unprognostic (9.09e-3)" "unprognostic (2.34e-3)" "unprognostic (3.17e-2)" "unprognostic (3.82e-2)" "unprognostic (1.12e-2)" BCL2L15 "Bfk, C1orf178, FLJ22588" ENSG00000188761 "BCL2 like 15" Q5TBC7 1 113876816-113887581 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 13.1;intestine: 42.0;stomach 1: 17.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 108.9;Exocrine glandular cells: 93.4;Gastric mucus-secreting cells: 35.4;Intestinal goblet cells: 39.8;Proximal enterocytes: 158.6;Undifferentiated cells: 41.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bile duct cancer: 13.6;colorectal cancer: 16.7;Gastric cancer: 6.7;pancreatic cancer: 4.8" "Colon - Colon enterocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in some" 32 "cerebellum: 32.9" "Low region specificity" "Detected in all" "HPA029732, HPA029733" Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 6 "HPA029732: AB_10599615, HPA029733: AB_10600422" "unprognostic (5.96e-2)" "unprognostic (6.41e-3)" "unprognostic (5.82e-2)" "prognostic favorable (5.63e-4)" "unprognostic (2.16e-1)" "unprognostic (6.23e-3)" "unprognostic (4.97e-4)" "unprognostic (1.74e-1)" "unprognostic (2.95e-1)" "unprognostic (1.46e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-1)" "unprognostic (2.42e-7)" "unprognostic (5.20e-2)" "unprognostic (2.24e-2)" "unprognostic (9.04e-3)" "unprognostic (4.27e-2)" BCO1 "BCDO, BCDO1, BCMO, BCMO1, FLJ10730" ENSG00000135697 "Beta-carotene oxygenase 1" Q9HAY6 16 81238689-81291142 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 11.8;intestine: 14.2" "Cell type enhanced" "Detected in some" "Astrocytes: 5.9;Basal prostatic cells: 14.9;Excitatory neurons: 7.8;Intestinal goblet cells: 6.5;Oocytes: 7.4;Proximal enterocytes: 12.4;Proximal tubular cells: 7.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 5.8" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043811 Approved "Actin filaments,Centriolar satellite" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 3: Basal prostatic cells - Lipid metabolism" "Actin filaments, Centriolar satellite" "HPA043811: AB_10962487" "unprognostic (2.78e-1)" "unprognostic (3.88e-3)" "unprognostic (2.61e-1)" "unprognostic (3.32e-1)" "unprognostic (4.05e-2)" "unprognostic (8.01e-4)" "unprognostic (1.65e-1)" "unprognostic (2.99e-2)" "unprognostic (1.58e-3)" "unprognostic (7.26e-2)" "unprognostic (2.97e-2)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.90e-2)" "unprognostic (2.48e-1)" "unprognostic (5.07e-2)" "unprognostic (1.09e-1)" BDH2 "DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308" ENSG00000164039 "3-hydroxybutyrate dehydrogenase 2" Q9BUT1 4 103077592-103099870 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 157.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 221.3;Proximal enterocytes: 187.0;Proximal tubular cells: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036028, HPA036029" Enhanced Supported Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 52: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Cytosol "HPA036028: AB_10670674, HPA036029: AB_2674909" "unprognostic (2.12e-2)" "unprognostic (1.91e-1)" "unprognostic (1.64e-1)" "prognostic favorable (5.21e-4)" "unprognostic (3.92e-1)" "unprognostic (2.28e-1)" "unprognostic (3.82e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.71e-1)" "unprognostic (2.04e-1)" "unprognostic (4.37e-1)" "unprognostic (1.95e-1)" "prognostic favorable (4.45e-13)" "unprognostic (2.54e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.75e-4)" "unprognostic (9.69e-3)" BICDL2 CCDC64B ENSG00000162069 "BICD family like cargo adaptor 2" A1A5D9 16 3027682-3036944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 101.9;pancreas: 123.5" "Cell type enhanced" "Detected in many" "Club cells: 98.6;Distal enterocytes: 220.8;Ionocytes: 103.1;Paneth cells: 119.1;Proximal enterocytes: 115.6;Suprabasal keratinocytes: 89.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 3.7" HPA043251 Approved Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 4 "Intermediate filaments, Actin filaments, Cytosol" "HPA043251: AB_10794925" "unprognostic (2.00e-1)" "unprognostic (5.37e-2)" "unprognostic (1.71e-1)" "unprognostic (6.06e-3)" "unprognostic (9.65e-5)" "unprognostic (5.79e-3)" "unprognostic (6.47e-2)" "unprognostic (1.75e-2)" "unprognostic (2.45e-1)" "unprognostic (1.66e-2)" "unprognostic (2.05e-2)" "unprognostic (4.71e-2)" "unprognostic (8.56e-2)" "unprognostic (2.55e-2)" "unprognostic (2.38e-1)" "unprognostic (4.32e-2)" "prognostic favorable (9.04e-4)" BIRC3 "API2, c-IAP2, cIAP2, hiap-1, MALT2, MIHC, RNF49" ENSG00000023445 "Baculoviral IAP repeat containing 3" Q13489 11 102317450-102339403 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 86.5;lymphoid tissue: 138.1" "Cell type enhanced" "Detected in many" "granulocytes: 1031.5;Langerhans cells: 1586.5;monocytes: 1328.0;Proximal enterocytes: 870.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 210.0;naive B-cell: 160.8" "Group enriched" "Detected in all" 13 "B-cells: 210.0;T-cells: 83.8" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 295.5" "Pancreas - Ductal cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002317 Enhanced Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 10 "Nucleoplasm, Cytosol" "HPA002317: AB_1846748" "prognostic favorable (3.60e-4)" "unprognostic (2.89e-1)" "prognostic favorable (9.35e-4)" "unprognostic (3.28e-2)" "prognostic unfavorable (7.28e-4)" "unprognostic (5.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.88e-3)" "unprognostic (9.62e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (3.03e-4)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.66e-6)" "unprognostic (6.42e-2)" "unprognostic (6.23e-3)" "unprognostic (1.00e-1)" "unprognostic (3.85e-2)" BLNK "BASH, bca, BLNK-s, Ly57, SLP-65, SLP65" ENSG00000095585 "B cell linker" Q8WV28 10 96189171-96271587 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "B-cells: 98.0;dendritic cells: 118.3;Microglial cells: 150.3;Plasma cells: 80.2;Proximal enterocytes: 81.4;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 111.3;naive B-cell: 94.9;plasmacytoid DC: 159.3" "Group enriched" "Detected in many" 83 "B-cells: 111.3;dendritic cells: 159.3" "Cancer enhanced" "Detected in many" "Leukemia: 18.6;lymphoma: 53.4" "Colon - T-cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009333, CAB016291, HPA038309, HPA038310" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 3 "Plasma membrane" Vesicles "CAB009333: AB_2290422, CAB016291: AB_626752, HPA038309: AB_2675945, HPA038310: AB_2675946" "unprognostic (4.86e-2)" "unprognostic (6.05e-3)" "unprognostic (1.00e-2)" "unprognostic (2.73e-2)" "unprognostic (2.29e-1)" "unprognostic (1.63e-3)" "unprognostic (1.08e-2)" "unprognostic (5.19e-2)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" "unprognostic (8.94e-2)" "unprognostic (3.73e-1)" "unprognostic (1.84e-2)" "unprognostic (5.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.46e-3)" "prognostic favorable (2.67e-6)" BLOC1S1 "BLOS1, BORCS1, GCN5L1" ENSG00000135441 "Biogenesis of lysosomal organelles complex 1 subunit 1" P78537 12 55716038-55720087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1022.3;Proximal enterocytes: 1149.7;Proximal tubular cells: 714.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021381 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 11 "HPA021381: AB_2228026" "unprognostic (1.27e-1)" "prognostic favorable (2.77e-4)" "unprognostic (1.65e-1)" "unprognostic (4.03e-2)" "unprognostic (1.10e-1)" "unprognostic (2.40e-1)" "unprognostic (1.59e-1)" "unprognostic (6.77e-2)" "unprognostic (2.22e-1)" "prognostic favorable (2.19e-4)" "unprognostic (6.51e-3)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-2)" "unprognostic (1.83e-2)" BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465764 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 615.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 2110.5;Hepatocytes: 827.2;Hofbauer cells: 1099.8;Proximal enterocytes: 929.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 466.2" "Group enriched" "Detected in all" 7 "dendritic cells: 343.8;monocytes: 466.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 370000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 40: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" 1 Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA041698: AB_10796781, HPA041937: AB_10794308" "unprognostic (1.86e-1)" "unprognostic (1.14e-2)" "unprognostic (4.23e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (1.20e-2)" "unprognostic (8.56e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" BMP3 ENSG00000152785 "Bone morphogenetic protein 3" P12645 4 81030708-81057627 "Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.0;lung: 5.3;ovary: 5.2;urinary bladder: 9.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 18.1;Club cells: 13.3;Distal enterocytes: 39.7;Mucus glandular cells: 15.7;Paneth cells: 37.3;Proximal enterocytes: 25.0;Salivary duct cells: 15.2;Undifferentiated cells: 14.7" "Group enriched" "Detected in some" 4 "lung cancer: 4.2;urothelial cancer: 7.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 2.9;lymphoma: 6.6" "Lung - Alveolar cells type 2, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in other tissues" Cytokine NA NA "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 5: Enterocytes - Absorption" "unprognostic (5.21e-3)" "unprognostic (1.00e-1)" "unprognostic (1.28e-1)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (3.36e-2)" "unprognostic (2.73e-3)" "unprognostic (9.11e-2)" "unprognostic (2.35e-1)" "unprognostic (1.94e-1)" "unprognostic (1.16e-4)" "unprognostic (2.26e-2)" "unprognostic (3.86e-1)" "unprognostic (1.11e-1)" "unprognostic (4.22e-2)" BOLA2B ENSG00000169627 "BolA family member 2B" Q9H3K6 16 30192932-30194306 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 41.5;Distal tubular cells: 83.0;Proximal enterocytes: 49.4;Proximal tubular cells: 41.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA045380, HPA046696" Supported Uncertain Nucleoplasm NA NA 390000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" 1 Nucleoplasm "HPA045380: AB_2679301, HPA046696: AB_2679757" "unprognostic (2.49e-1)" "unprognostic (4.60e-3)" "unprognostic (8.49e-2)" "unprognostic (3.02e-3)" "unprognostic (9.80e-4)" "unprognostic (1.22e-1)" "unprognostic (3.75e-2)" "unprognostic (1.25e-1)" "unprognostic (3.08e-2)" "unprognostic (2.24e-2)" "unprognostic (1.26e-1)" "unprognostic (5.75e-2)" "unprognostic (1.70e-1)" "unprognostic (2.94e-1)" "unprognostic (5.29e-1)" "unprognostic (2.21e-2)" "unprognostic (4.91e-3)" BPHL "Bph-rp, MCNAA, VACVase" ENSG00000137274 "Biphenyl hydrolase like" Q86WA6 6 3118374-3153578 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 106.1;liver: 82.0" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 103.5;Proximal tubular cells: 246.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036752, HPA036753" Enhanced Approved Mitochondria NA NA 14000 "Cluster 18: Non-specific - Translation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria "HPA036752: AB_10673662, HPA036753: AB_2675291" "unprognostic (2.93e-1)" "unprognostic (1.29e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-1)" "unprognostic (3.72e-3)" "unprognostic (1.84e-1)" "unprognostic (8.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.97e-4)" "unprognostic (4.59e-2)" "unprognostic (9.46e-3)" "prognostic favorable (5.16e-7)" "unprognostic (1.60e-2)" "unprognostic (1.51e-2)" "unprognostic (6.98e-2)" "unprognostic (5.20e-2)" BPNT1 ENSG00000162813 "3'(2'), 5'-bisphosphate nucleotidase 1" O95861 1 220057482-220090462 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 51.3;Proximal enterocytes: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048461 Approved Approved "Nuclear speckles" NA NA 420000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 5: Enterocytes - Absorption" "Nuclear speckles" "HPA048461: AB_2680404" "unprognostic (6.42e-2)" "unprognostic (4.69e-2)" "unprognostic (2.78e-2)" "unprognostic (1.02e-1)" "unprognostic (5.19e-3)" "unprognostic (7.65e-2)" "unprognostic (2.07e-2)" "unprognostic (3.00e-1)" "unprognostic (2.44e-1)" "unprognostic (1.66e-1)" "unprognostic (6.69e-2)" "unprognostic (2.87e-1)" "prognostic favorable (6.38e-4)" "unprognostic (1.82e-2)" "unprognostic (6.58e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-1)" C11orf24 DM4E3 ENSG00000171067 "Chromosome 11 open reading frame 24" Q96F05 11 68261338-68272001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 103.7;Plasma cells: 78.3;Proximal enterocytes: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012411, HPA012748" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 7 "Nucleoplasm, Golgi apparatus" Vesicles "HPA012411: , HPA012748: AB_1845526" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (1.19e-1)" "unprognostic (8.22e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.31e-2)" "unprognostic (7.91e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.56e-1)" "unprognostic (2.68e-2)" "unprognostic (4.99e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.60e-9)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (8.67e-3)" C19orf33 "H2RSP, IMUP, IMUP-1, IMUP-2" ENSG00000167644 "Chromosome 19 open reading frame 33" Q9GZP8 19 38304164-38305006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 500.9;skin 1: 320.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2497.3;Intestinal goblet cells: 784.7;Paneth cells: 1264.3;Proximal enterocytes: 1796.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 10 "myeloid DC: 22.3" "Lineage enriched" "Detected in many" 10 "dendritic cells: 22.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 1, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "HPA054406, HPA059696" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 460000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "HPA054406: AB_2682478, HPA059696: AB_2684105" "unprognostic (9.31e-2)" "unprognostic (2.06e-1)" "unprognostic (4.34e-2)" "unprognostic (1.44e-2)" "unprognostic (3.92e-3)" "unprognostic (2.37e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (5.42e-4)" "unprognostic (2.09e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (6.92e-2)" "unprognostic (5.50e-2)" "unprognostic (4.82e-2)" "unprognostic (1.61e-1)" "unprognostic (3.63e-2)" "unprognostic (6.01e-2)" C1orf115 "FLJ14146, RDD1" ENSG00000162817 "Chromosome 1 open reading frame 115" Q9H7X2 1 220690363-220699153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 117.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 109.3;Proximal enterocytes: 224.3;Syncytiotrophoblasts: 204.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (5.16e-2)" "prognostic favorable (6.52e-4)" "unprognostic (1.31e-1)" "unprognostic (3.93e-2)" "unprognostic (2.03e-1)" "unprognostic (5.69e-3)" "unprognostic (8.65e-2)" "prognostic favorable (5.12e-5)" "unprognostic (3.11e-1)" "unprognostic (1.33e-1)" "unprognostic (1.74e-2)" "unprognostic (4.24e-1)" "unprognostic (4.54e-2)" "unprognostic (9.21e-3)" "unprognostic (1.07e-1)" C1orf210 "MGC52423, TEMP" ENSG00000253313 "Chromosome 1 open reading frame 210" Q8IVY1 1 43281877-43285617 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 123.1;Enteroendocrine cells: 46.7;Paneth cells: 62.0;Proximal enterocytes: 134.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 2.2" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.2" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013788 Uncertain Uncertain "Nucleoli,Nucleoli rim" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 5: Enterocytes - Absorption" "Nucleoli, Nucleoli rim" "HPA013788: AB_1845637" "unprognostic (1.38e-2)" "unprognostic (1.08e-1)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (1.42e-1)" "unprognostic (1.66e-1)" "unprognostic (1.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.54e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (0.00e+0)" "unprognostic (7.57e-3)" "unprognostic (3.94e-1)" "unprognostic (1.00e-1)" "unprognostic (1.61e-2)" C20orf202 ENSG00000215595 "Chromosome 20 open reading frame 202" A1L168 20 1203454-1209076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 2.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.9;Early spermatids: 2.1;Horizontal cells: 1.3;Late spermatids: 3.5;Paneth cells: 1.2;Proximal enterocytes: 1.5;Sertoli cells: 2.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Thyroid - Fibroblasts" "Group enriched" "Detected in some" 15 "cerebellum: 8.0;olfactory bulb: 2.6" "Low region specificity" "Detected in many" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 11: Late spermatids - Unknown function" 7 "unprognostic (8.20e-2)" "unprognostic (1.66e-1)" "unprognostic (7.27e-2)" "unprognostic (2.73e-2)" "unprognostic (3.49e-3)" "unprognostic (1.92e-3)" "unprognostic (1.15e-2)" "unprognostic (7.41e-3)" "unprognostic (1.92e-1)" "unprognostic (7.40e-2)" "unprognostic (1.29e-2)" "unprognostic (7.55e-2)" "unprognostic (5.82e-3)" "unprognostic (7.98e-2)" "unprognostic (5.70e-3)" "unprognostic (1.26e-1)" "unprognostic (7.24e-3)" C2CD2L "KIAA0285, TMEM24" ENSG00000172375 "C2CD2 like" O14523 11 119102198-119118544 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011044, HPA075369" Approved Supported "Plasma membrane" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" 31 "Plasma membrane" "HPA011044: AB_2668414, HPA075369: " "unprognostic (3.43e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-3)" "prognostic favorable (4.92e-4)" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-3)" "unprognostic (3.37e-3)" "unprognostic (5.28e-2)" "unprognostic (2.09e-1)" "unprognostic (3.99e-3)" "unprognostic (8.19e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (8.02e-2)" "unprognostic (8.32e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" C2orf88 "MGC13057, smAKAP" ENSG00000187699 "Chromosome 2 open reading frame 88" Q9BSF0 2 189879609-190203484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 71.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 388.1;Early spermatids: 708.8;Glandular and luminal cells: 239.6;Late spermatids: 1567.5;Proximal enterocytes: 436.3" "Group enriched" "Detected in many" 4 "endometrial cancer: 16.2;glioma: 4.8;ovarian cancer: 14.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.7;naive B-cell: 2.9;neutrophil: 7.3;plasmacytoid DC: 3.0" "Group enriched" "Detected in many" 8 "B-cells: 2.9;dendritic cells: 3.0;granulocytes: 7.3" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049549 Approved NA NA 160000 "Cluster 20: Non-specific - DNA binding" "Cluster 46: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 11: Late spermatids - Unknown function" 3 "HPA049549: AB_2680812" "unprognostic (1.20e-4)" "unprognostic (9.17e-2)" "unprognostic (4.50e-2)" "prognostic favorable (4.97e-4)" "unprognostic (6.09e-3)" "unprognostic (4.55e-2)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "prognostic unfavorable (9.39e-4)" "unprognostic (5.29e-3)" "unprognostic (2.66e-1)" "unprognostic (1.18e-1)" "prognostic favorable (7.79e-4)" "unprognostic (2.64e-2)" "unprognostic (2.72e-1)" "unprognostic (6.95e-2)" "unprognostic (1.18e-3)" C4orf19 FLJ11017 ENSG00000154274 "Chromosome 4 open reading frame 19" Q8IY42 4 37453925-37623495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 34.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 83.9;Distal enterocytes: 109.7;Enteroendocrine cells: 76.0;Exocrine glandular cells: 114.3;Proximal enterocytes: 105.0;Syncytiotrophoblasts: 97.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 8.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.4" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043458, HPA052894" Enhanced Approved "Nucleoplasm,Cell Junctions" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Non-specific - Mixed function" 4 Nucleoplasm "Cell Junctions" "HPA043458: AB_10960696, HPA052894: AB_2681982" "unprognostic (8.83e-2)" "unprognostic (7.86e-2)" "unprognostic (3.00e-3)" "unprognostic (2.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.59e-3)" "unprognostic (5.55e-2)" "unprognostic (2.29e-1)" "unprognostic (6.66e-2)" "unprognostic (9.96e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.49e-11)" "unprognostic (1.33e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-3)" "unprognostic (8.19e-3)" C6orf132 bA7K24.2 ENSG00000188112 "Chromosome 6 open reading frame 132" Q5T0Z8 6 42092233-42142620 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 152.6;skin 1: 71.3" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 106.5;Late spermatids: 148.4;Proximal enterocytes: 108.0;Suprabasal keratinocytes: 163.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 95.2" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA044588 Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 45: Non-specific - Mixed function" "Golgi apparatus, Cytosol" "HPA044588: AB_10794293" "unprognostic (7.09e-2)" "unprognostic (8.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.24e-3)" "unprognostic (1.60e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (6.78e-2)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "prognostic unfavorable (4.90e-4)" "unprognostic (1.31e-1)" "unprognostic (4.26e-3)" "unprognostic (1.04e-2)" "unprognostic (5.53e-2)" "unprognostic (2.47e-2)" "unprognostic (1.30e-1)" C6orf136 Em:AB023049.8 ENSG00000204564 "Chromosome 6 open reading frame 136" Q5SQH8 6 30647039-30653210 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal enterocytes: 87.7;Oocytes: 99.3;Proximal enterocytes: 106.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046804 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 5: Enterocytes - Absorption" "HPA046804: AB_2679815" "unprognostic (1.94e-2)" "unprognostic (1.71e-3)" "unprognostic (1.26e-1)" "unprognostic (8.01e-3)" "unprognostic (1.65e-2)" "unprognostic (2.76e-2)" "unprognostic (1.61e-1)" "unprognostic (1.79e-1)" "unprognostic (2.13e-1)" "unprognostic (2.62e-2)" "unprognostic (4.72e-3)" "unprognostic (3.43e-1)" "prognostic favorable (9.16e-8)" "unprognostic (2.33e-2)" "unprognostic (4.54e-2)" "unprognostic (6.03e-2)" "prognostic favorable (7.51e-4)" CA13 "CAXIII, FLJ37995, MGC59868" ENSG00000185015 "Carbonic anhydrase 13" Q8N1Q1 8 85220587-85284073 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.2" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024689, CAB025567" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA 27000 "Cluster 41: Basophils - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 Nucleoli "Nucleoplasm, Vesicles" "CAB025567: , HPA024689: AB_1846004" "unprognostic (1.12e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (9.16e-5)" "unprognostic (2.21e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (7.90e-3)" "unprognostic (1.97e-1)" "unprognostic (1.34e-2)" "unprognostic (3.58e-2)" "unprognostic (3.13e-1)" "prognostic favorable (9.40e-4)" "unprognostic (7.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.00e-1)" CALML4 "MGC4809, NY-BR-20" ENSG00000129007 "Calmodulin like 4" Q96GE6 15 68190705-68206079 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 28.1;intestine: 37.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 24.6;Gastric mucus-secreting cells: 22.4;Paneth cells: 12.2;Proximal enterocytes: 23.3;Proximal tubular cells: 32.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "choroid plexus: 13.7" "Group enriched" "Detected in some" 40 "classical monocyte: 30.8;intermediate monocyte: 56.6;myeloid DC: 18.4;neutrophil: 18.1;non-classical monocyte: 66.4" "Group enriched" "Detected in many" 59 "dendritic cells: 18.4;granulocytes: 18.1;monocytes: 66.4" "Cancer enhanced" "Detected in all" "Myeloma: 61.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051109 Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA051109: AB_2681346" "unprognostic (1.69e-2)" "unprognostic (1.78e-1)" "unprognostic (4.97e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (3.71e-2)" "unprognostic (4.05e-2)" "unprognostic (6.53e-2)" "unprognostic (6.77e-2)" "unprognostic (2.10e-1)" "unprognostic (4.19e-3)" "unprognostic (6.24e-2)" "unprognostic (3.85e-2)" "unprognostic (7.92e-3)" "unprognostic (2.46e-1)" "unprognostic (7.49e-2)" "unprognostic (1.32e-1)" CAPN13 FLJ23523 ENSG00000162949 "Calpain 13" Q6MZZ7 2 30722771-30820542 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.4;stomach 1: 27.8" "Cell type enhanced" "Detected in some" "Club cells: 84.9;Distal enterocytes: 20.5;Gastric mucus-secreting cells: 53.1;Ionocytes: 31.3;Oocytes: 18.4;Proximal enterocytes: 32.6;Undifferentiated cells: 18.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.3" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029496, HPA029497, HPA030034" Uncertain Approved Nucleoplasm NA NA "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" Nucleoplasm "HPA029496: AB_2673072, HPA029497: AB_2673073, HPA030034: AB_2673281" "unprognostic (7.42e-2)" "unprognostic (1.19e-1)" "unprognostic (7.01e-3)" "unprognostic (1.96e-1)" "unprognostic (8.56e-2)" "unprognostic (1.51e-1)" "unprognostic (1.68e-1)" "unprognostic (1.32e-3)" "unprognostic (2.17e-1)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-1)" "unprognostic (1.96e-2)" "unprognostic (3.64e-1)" "unprognostic (3.32e-2)" "unprognostic (5.03e-2)" "unprognostic (4.28e-3)" CAPN5 "ADNIV, HTRA3, nCL-3, VRNI" ENSG00000149260 "Calpain 5" O15484 11 77066961-77126155 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 59.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 140.1;Gastric mucus-secreting cells: 71.9;Intestinal goblet cells: 104.6;Paneth cells: 68.4;Proximal enterocytes: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033237, HPA072319" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm Cytosol "CAB033237: AB_2069673, HPA072319: AB_2686512" "unprognostic (6.81e-3)" "unprognostic (1.31e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (3.47e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-1)" "unprognostic (2.21e-2)" "unprognostic (5.35e-3)" "unprognostic (4.64e-1)" "unprognostic (3.17e-3)" "unprognostic (8.58e-3)" "unprognostic (3.25e-1)" "unprognostic (2.31e-2)" "unprognostic (2.30e-3)" CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.9" "Cell type enhanced" "Detected in many" "Adipocytes: 23.2;Ductal cells: 25.3;Endothelial cells: 28.4;Intestinal goblet cells: 26.1;Lymphatic endothelial cells: 29.0;Proximal enterocytes: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Prostate - Endothelial cells, Testis - Sertoli cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 83 "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" CASP1 "ICE, IL1BC" ENSG00000137752 "Caspase 1" P29466 11 105025397-105035250 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 125.9;lymphoid tissue: 88.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 147.2;Kupffer cells: 93.9;Langerhans cells: 151.1;Macrophages: 115.9;monocytes: 201.9;Proximal enterocytes: 116.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid - T-cells" "Region enhanced" "Detected in all" "olfactory bulb: 18.4" "Low region specificity" "Detected in all" "CAB002685, HPA003056" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 29: Monocytes - Innate immune response" 9 Cytosol Nucleoplasm "CAB002685: , HPA003056: AB_1846037" "unprognostic (1.21e-3)" "unprognostic (3.02e-1)" "unprognostic (9.47e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (6.67e-2)" "unprognostic (2.75e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.03e-2)" "unprognostic (2.30e-2)" "unprognostic (3.18e-1)" "unprognostic (5.19e-2)" CASP7 "CMH-1, ICE-LAP3, MCH3" ENSG00000165806 "Caspase 7" P55210 10 113679162-113730907 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Allosteric enzyme, Hydrolase, Protease, RNA-binding, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 152.6;Proximal enterocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025563 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 5: Enterocytes - Absorption" 10 "CAB025563: " "prognostic favorable (2.11e-4)" "unprognostic (3.18e-2)" "unprognostic (2.82e-2)" "unprognostic (2.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-3)" "unprognostic (3.96e-1)" "unprognostic (2.04e-1)" "unprognostic (1.22e-2)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "prognostic unfavorable (5.90e-4)" "unprognostic (5.45e-3)" "unprognostic (2.62e-1)" "unprognostic (2.86e-1)" "unprognostic (4.33e-3)" CBLC "CBL-3, CBL-SL, RNF57" ENSG00000142273 "Cbl proto-oncogene C" Q9ULV8 19 44777869-44800652 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 38.2;intestine: 49.5;skin 1: 41.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 128.3;Gastric mucus-secreting cells: 55.4;Paneth cells: 99.9;Proximal enterocytes: 159.3;Undifferentiated cells: 53.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "CAB008087, HPA035266" Approved Approved Nucleoplasm,Aggresome NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 6 Nucleoplasm Aggresome "CAB008087: AB_2228531, HPA035266: AB_2674542" "unprognostic (1.58e-1)" "unprognostic (2.25e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-1)" "unprognostic (3.04e-2)" "unprognostic (3.91e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (3.82e-1)" "unprognostic (7.39e-2)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "prognostic favorable (3.11e-6)" "unprognostic (3.50e-1)" "unprognostic (8.25e-3)" "unprognostic (2.90e-2)" "unprognostic (2.21e-3)" CBR1 "CBR, SDR21C1" ENSG00000159228 "Carbonyl reductase 1" P16152 21 36069941-36073166 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 389.9;intestine: 567.1" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 425.0;Distal tubular cells: 608.5;Proximal enterocytes: 1350.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 422.3" "Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018433, CAB034291" Enhanced Approved Nucleoplasm,Cytosol NA NA 12000000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 2 Nucleoplasm Cytosol "CAB034291: AB_2070856, HPA018433: AB_1846109" "prognostic favorable (2.18e-4)" "unprognostic (9.78e-2)" "unprognostic (3.25e-2)" "unprognostic (2.14e-1)" "unprognostic (6.47e-3)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" "unprognostic (6.37e-2)" "unprognostic (4.56e-2)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (4.00e-1)" "prognostic favorable (4.75e-4)" "unprognostic (2.37e-1)" "unprognostic (2.47e-1)" "unprognostic (6.13e-3)" "unprognostic (2.47e-2)" CCDC68 SE57-1 ENSG00000166510 "Coiled-coil domain containing 68" Q9H2F9 18 54901509-54959461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.1;placenta: 31.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.5;Early spermatids: 122.3;Endothelial cells: 47.3;Paneth cells: 48.7;Proximal enterocytes: 56.1" "Cancer enhanced" "Detected in many" "stomach cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040865, HPA048197" Supported Approved "Golgi apparatus,Cytosol" No NA "Cluster 25: Small intestine - Absorption" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 4 "Golgi apparatus" Cytosol "HPA040865: AB_2677176, HPA048197: AB_2680310" "unprognostic (1.36e-2)" "prognostic unfavorable (4.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.38e-2)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (2.65e-2)" "unprognostic (6.29e-2)" "unprognostic (2.71e-1)" "unprognostic (1.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.77e-2)" "unprognostic (9.71e-2)" "unprognostic (6.12e-2)" "unprognostic (2.38e-1)" CD68 "DKFZp686M18236, GP110, LAMP4, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 346.5;lymphoid tissue: 360.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 223.6;Kupffer cells: 258.2;Langerhans cells: 80.9;Macrophages: 190.0;Proximal enterocytes: 193.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3264.9;intermediate monocyte: 3664.2;non-classical monocyte: 3764.8" "Group enriched" "Detected in all" 11 "dendritic cells: 1382.0;monocytes: 3764.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 7 "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" CD74 "CLIP, DHLAG" ENSG00000019582 "CD74 molecule" P04233 5 150401637-150412969 "Cancer-related genes, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 5112.2" "Cell type enhanced" "Detected in many" "B-cells: 11727.2;dendritic cells: 8645.4;Hofbauer cells: 5396.5;Langerhans cells: 26767.6;Macrophages: 7008.6;Proximal enterocytes: 5477.7;Schwann cells: 10143.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 11129.6;intermediate monocyte: 16174.8;memory B-cell: 27121.2;myeloid DC: 23965.9;naive B-cell: 28192.5;non-classical monocyte: 8146.1;plasmacytoid DC: 17015.9" "Group enriched" "Detected in all" 6 "B-cells: 28192.5;dendritic cells: 23965.9;monocytes: 16174.8" "Group enriched" "Detected in many" 7 "Leukemia: 998.7;lymphoma: 3214.7;Myeloma: 1807.4;skin cancer: 961.7" "Adipose visceral - T-cells, Testis - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002506, HPA010592, CAB079994" Enhanced Supported "Golgi apparatus" NA NA 210000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" 7 "Golgi apparatus" "CAB002506: AB_563630, CAB079994: , HPA010592: AB_1078482" "prognostic favorable (1.06e-4)" "unprognostic (1.48e-2)" "unprognostic (4.80e-3)" "prognostic favorable (6.53e-6)" "unprognostic (1.41e-1)" "unprognostic (4.53e-2)" "unprognostic (2.05e-1)" "unprognostic (3.69e-3)" "unprognostic (1.54e-2)" "unprognostic (3.48e-2)" "unprognostic (2.20e-2)" "unprognostic (2.64e-1)" "unprognostic (5.44e-3)" "unprognostic (1.73e-1)" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (4.24e-2)" CD82 "IA4, KAI1, R2, ST6, TSPAN27" ENSG00000085117 "CD82 molecule" P27701 11 44564427-44620358 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 203.0;Proximal enterocytes: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 537.1" "Group enriched" "Detected in all" 6 "B-cells: 308.8;granulocytes: 537.1;T-cells: 172.7" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Mitotic cells (Stomach)" "Region enhanced" "Detected in all" "white matter: 210.9" "Low region specificity" "Detected in all" "CAB002508, HPA028900, HPA061418" Supported Uncertain Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 19: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 30: Granulocytes - Unknown function" 5 Vesicles "CAB002508: AB_563640, HPA028900: AB_10603558, HPA061418: AB_2684510" "unprognostic (5.31e-2)" "unprognostic (4.62e-1)" "unprognostic (2.38e-2)" "unprognostic (1.33e-1)" "unprognostic (2.79e-1)" "unprognostic (1.37e-2)" "unprognostic (1.78e-1)" "unprognostic (7.29e-2)" "unprognostic (3.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.58e-2)" "unprognostic (1.58e-1)" "unprognostic (3.48e-3)" "unprognostic (1.86e-3)" "unprognostic (2.33e-2)" "unprognostic (2.88e-2)" "unprognostic (6.30e-2)" CDA CDD ENSG00000158825 "Cytidine deaminase" P32320 1 20589086-20618903 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 191.4;esophagus: 84.6;liver: 84.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 309.9;Hepatocytes: 135.1;monocytes: 104.5;Paneth cells: 145.5;Proximal enterocytes: 117.2;Suprabasal keratinocytes: 190.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 1240.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 1240.3" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 157.8" "Lung - Neutrophil_2, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA064202 Enhanced Approved Nucleoplasm NA NA 3700000 "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 14 Nucleoplasm "HPA064202: AB_2685211" "unprognostic (2.38e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (2.86e-1)" "unprognostic (2.56e-1)" "unprognostic (8.02e-2)" "unprognostic (3.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.68e-3)" "unprognostic (2.64e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (8.56e-5)" "unprognostic (2.94e-2)" "unprognostic (5.03e-2)" "unprognostic (8.47e-3)" "unprognostic (2.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.89e-3)" CDCA3 "GRCC8, TOME-1" ENSG00000111665 "Cell division cycle associated 3" Q99618 12 6844793-6851292 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.7;retina: 64.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.3;Erythroid cells: 48.8;Extravillous trophoblasts: 80.4;Proximal enterocytes: 67.7;Spermatocytes: 64.7;Undifferentiated cells: 31.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA026587 Approved Cytosol NA Yes "Cluster 14: Non-specific - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 4 Cytosol "HPA026587: AB_1846386" "unprognostic (3.05e-1)" "unprognostic (1.32e-1)" "unprognostic (9.85e-2)" "unprognostic (1.63e-2)" "unprognostic (2.42e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.51e-5)" "prognostic unfavorable (9.77e-5)" "unprognostic (3.88e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-3)" "unprognostic (8.81e-2)" "unprognostic (0.00e+0)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.11e-1)" "unprognostic (4.94e-2)" CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.2;intestine: 30.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 85.9;Distal enterocytes: 171.2;Proximal enterocytes: 127.2;Squamous epithelial cells: 167.0;Suprabasal keratinocytes: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Endothelial cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB000349, HPA052838, HPA063327, HPA073143" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 15 Nucleoplasm Cytosol "CAB000349: , HPA052838: , HPA063327: AB_2684987, HPA073143: " "unprognostic (2.30e-1)" "unprognostic (9.23e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (4.47e-6)" "unprognostic (2.10e-1)" "unprognostic (7.40e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.01e-1)" "unprognostic (3.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.03e-4)" "unprognostic (9.14e-3)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.28e-2)" CENPV "CENP-V, p30, PRR6" ENSG00000166582 "Centromere protein V" Q7Z7K6 17 16342534-16353656 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Paneth cells: 91.7;Proximal enterocytes: 101.9;Spermatocytes: 92.5;Spermatogonia: 117.2;Undifferentiated cells: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "HPA042529, HPA042616" Enhanced Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 14 Nucleoplasm "Midbody, Cytosol" "HPA042529: AB_10793882, HPA042616: AB_10794050" "unprognostic (7.64e-2)" "unprognostic (4.41e-2)" "unprognostic (5.92e-2)" "unprognostic (9.66e-3)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (2.24e-1)" "unprognostic (6.47e-2)" "unprognostic (1.21e-1)" "unprognostic (4.00e-2)" "unprognostic (7.73e-3)" "unprognostic (7.93e-2)" "unprognostic (4.09e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-2)" "unprognostic (2.54e-2)" "unprognostic (3.60e-3)" CFDP1 "BCNT, CENP-29, CP27, p97, SWC5, Yeti" ENSG00000153774 "Craniofacial development protein 1" Q9UEE9 16 75293698-75433503 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 602.0;Proximal tubular cells: 650.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041316, HPA048242" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 5: Enterocytes - Absorption" Nucleoplasm Vesicles "HPA041316: AB_10794371, HPA048242: AB_2680327" "unprognostic (1.45e-1)" "unprognostic (8.64e-2)" "unprognostic (1.13e-1)" "unprognostic (4.88e-1)" "unprognostic (3.97e-2)" "prognostic unfavorable (9.63e-5)" "unprognostic (5.81e-3)" "unprognostic (2.17e-1)" "unprognostic (1.26e-2)" "unprognostic (2.61e-2)" "unprognostic (1.42e-1)" "unprognostic (7.37e-2)" "unprognostic (2.85e-2)" "unprognostic (6.54e-2)" "unprognostic (1.36e-1)" "unprognostic (4.92e-3)" "unprognostic (1.25e-1)" CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 54.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 177.3;Alveolar cells type 2: 57.9;Distal enterocytes: 113.1;Mesothelial cells: 81.6;Proximal enterocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" 3 "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: AB_10600208, HPA027587: AB_10601884, HPA027657: AB_10611527" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.74e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (4.61e-1)" "unprognostic (2.11e-2)" "unprognostic (2.96e-3)" "unprognostic (7.10e-2)" "prognostic favorable (5.84e-10)" "unprognostic (2.66e-1)" "unprognostic (3.00e-1)" "unprognostic (8.28e-2)" "unprognostic (2.10e-2)" CHCHD10 "C22orf16, MIX17A, N27C7-4" ENSG00000250479 "Coiled-coil-helix-coiled-coil-helix domain containing 10" Q8WYQ3 22 23765834-23767972 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1571.6;skeletal muscle: 1177.8" "Cell type enhanced" "Detected in all" "Distal enterocytes: 2165.4;Distal tubular cells: 2342.0;Hepatocytes: 2128.9;Proximal enterocytes: 1596.0;Proximal tubular cells: 1514.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003440 Enhanced Supported Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 3 Mitochondria "HPA003440: AB_1078348" "unprognostic (3.88e-2)" "unprognostic (2.36e-3)" "unprognostic (8.90e-2)" "unprognostic (9.80e-2)" "unprognostic (7.68e-2)" "unprognostic (5.97e-3)" "unprognostic (1.59e-1)" "unprognostic (1.85e-1)" "unprognostic (2.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.61e-1)" "unprognostic (5.13e-2)" "prognostic favorable (2.15e-7)" "unprognostic (5.19e-3)" "unprognostic (2.06e-1)" "unprognostic (5.68e-3)" "unprognostic (2.62e-3)" CHDH ENSG00000016391 "Choline dehydrogenase" Q8NE62 3 53812335-53846419 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 36.2;liver: 34.9" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 63.6;Proximal tubular cells: 72.6;Undifferentiated cells: 50.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14 "basophil: 3.0;T-reg: 1.3" "Group enriched" "Detected in many" 18 "granulocytes: 3.0;T-cells: 1.3" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036633, HPA058130" Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 52: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 2 "HPA036633: AB_10670841, HPA058130: AB_2683615" "unprognostic (3.40e-3)" "unprognostic (1.17e-2)" "unprognostic (2.26e-3)" "unprognostic (7.17e-3)" "unprognostic (9.15e-2)" "unprognostic (1.17e-3)" "unprognostic (1.10e-1)" "unprognostic (1.97e-2)" "unprognostic (2.75e-1)" "unprognostic (4.35e-3)" "unprognostic (4.57e-2)" "unprognostic (5.12e-2)" "prognostic favorable (1.88e-8)" "unprognostic (3.37e-2)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (2.29e-2)" CHMP4A "C14orf123, HSPC134, VPS32A" ENSG00000254505 "Charged multivesicular body protein 4A" Q9BY43 14 24209615-24213830 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 69.8;Exocrine glandular cells: 53.8;Pancreatic endocrine cells: 56.0;Proximal enterocytes: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" HPA068473 Approved NA NA 1400000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 53: Non-specific - Glycosylation" "Cluster 47: Endothelial cells - Vasculature" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 14: Langerhans cells - Innate immune response" 3 "HPA068473: AB_2685994" "unprognostic (4.33e-3)" "unprognostic (3.76e-2)" "unprognostic (4.29e-2)" "unprognostic (5.45e-2)" "unprognostic (4.29e-1)" "unprognostic (1.25e-1)" "unprognostic (1.74e-4)" "unprognostic (2.02e-3)" "unprognostic (9.61e-2)" "unprognostic (1.76e-2)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (3.91e-8)" "unprognostic (3.30e-1)" "unprognostic (3.42e-1)" "unprognostic (7.37e-2)" "unprognostic (6.90e-2)" CHMP4B "C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B" ENSG00000101421 "Charged multivesicular body protein 4B" Q9H444 20 33811348-33854366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 489.3;Syncytiotrophoblasts: 470.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041401, HPA051751" Enhanced NA NA 53000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 45: Non-specific - Mixed function" 14 "HPA041401: AB_10965028, HPA051751: AB_2681591" "unprognostic (2.56e-2)" "unprognostic (6.12e-2)" "unprognostic (1.07e-1)" "unprognostic (9.04e-3)" "unprognostic (9.85e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.49e-1)" "unprognostic (4.37e-2)" "unprognostic (1.24e-2)" "unprognostic (6.44e-3)" "unprognostic (1.31e-1)" "unprognostic (6.09e-2)" "unprognostic (2.31e-1)" "unprognostic (5.50e-2)" "unprognostic (1.20e-2)" "unprognostic (3.33e-2)" CHMP4C "MGC22825, Shax3, VPS32C" ENSG00000164695 "Charged multivesicular body protein 4C" Q96CF2 8 81732448-81759515 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.7" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 79.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.9" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023763, HPA023799" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" 2 "Microtubules, Cytokinetic bridge" "HPA023763: , HPA023799: AB_1846670" "unprognostic (3.98e-2)" "unprognostic (6.75e-3)" "unprognostic (1.58e-1)" "unprognostic (5.19e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (9.33e-5)" "unprognostic (7.54e-2)" "unprognostic (8.08e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.99e-2)" "prognostic favorable (1.96e-6)" "unprognostic (3.29e-3)" "unprognostic (4.95e-1)" "unprognostic (2.67e-1)" "prognostic favorable (6.45e-4)" CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 423.4;Distal tubular cells: 424.1;Hepatocytes: 343.0;Proximal enterocytes: 403.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 1 Vesicles "HPA006616: AB_1857461" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (2.84e-1)" "prognostic favorable (9.63e-4)" "unprognostic (7.29e-2)" "unprognostic (3.74e-1)" "prognostic favorable (4.07e-6)" "unprognostic (2.20e-1)" "unprognostic (7.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-3)" "unprognostic (2.79e-1)" "prognostic favorable (2.79e-6)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-3)" "unprognostic (2.04e-1)" CHRNA7 ENSG00000175344 "Cholinergic receptor nicotinic alpha 7 subunit" P36544 15 31923438-32173018 "FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.5;intestine: 9.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 31.2;Horizontal cells: 29.0;Inhibitory neurons: 29.4;Intestinal goblet cells: 31.1;Proximal enterocytes: 27.3;Spermatogonia: 16.2" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 16.8" "Colon - Colon enteroendocrine cells" "HPA029422, CAB033624" Enhanced NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 4 "CAB033624: AB_784835, HPA029422: AB_10600863" "unprognostic (3.43e-2)" "unprognostic (8.44e-2)" "unprognostic (2.02e-1)" "unprognostic (4.61e-4)" "unprognostic (6.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.14e-2)" "unprognostic (5.08e-2)" "unprognostic (1.63e-1)" "unprognostic (4.31e-2)" "unprognostic (3.22e-1)" "unprognostic (1.05e-1)" "unprognostic (2.40e-2)" "unprognostic (4.36e-3)" "unprognostic (5.44e-2)" "unprognostic (7.41e-3)" "unprognostic (2.43e-1)" CISD1 "C10orf70, MDS029, mitoNEET, ZCD1" ENSG00000122873 "CDGSH iron sulfur domain 1" Q9NZ45 10 58269162-58289586 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 79.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 436.0;Distal tubular cells: 627.0;Proximal enterocytes: 543.8;Proximal tubular cells: 725.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074383 Supported Supported Mitochondria NA NA 13000 "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA074383: AB_2686684" "prognostic unfavorable (1.11e-4)" "unprognostic (8.60e-3)" "unprognostic (1.07e-1)" "unprognostic (4.10e-3)" "unprognostic (2.41e-2)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.87e-2)" "unprognostic (2.35e-1)" "unprognostic (7.78e-2)" "unprognostic (1.33e-2)" "unprognostic (7.23e-2)" "unprognostic (1.34e-3)" "unprognostic (4.19e-2)" "unprognostic (7.20e-2)" "unprognostic (8.07e-2)" "prognostic unfavorable (6.69e-4)" CISD3 "Miner2, MiNT" ENSG00000277972 "CDGSH iron sulfur domain 3" P0C7P0 17 38730341-38735605 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal enterocytes: 478.6;Hepatocytes: 722.3;Paneth cells: 364.1;Proximal enterocytes: 751.7;Proximal tubular cells: 471.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053436, HPA054400" Approved NA NA "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" "HPA053436: AB_2682149, HPA054400: AB_2682475" "unprognostic (9.42e-2)" "unprognostic (8.73e-2)" "unprognostic (7.64e-2)" "unprognostic (2.38e-2)" "unprognostic (2.75e-1)" "unprognostic (1.50e-2)" "unprognostic (1.32e-1)" "unprognostic (4.81e-1)" "unprognostic (1.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.76e-1)" "unprognostic (1.95e-1)" "unprognostic (2.88e-2)" "unprognostic (1.31e-2)" "unprognostic (2.12e-2)" "unprognostic (3.34e-1)" "unprognostic (1.42e-1)" CKMT1A CKMT1 ENSG00000223572 "Creatine kinase, mitochondrial 1A" P12532 15 43692886-43699222 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.7;esophagus: 81.5;intestine: 72.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 66.6;Distal enterocytes: 151.6;Enteroendocrine cells: 75.9;Paneth cells: 63.3;Proximal enterocytes: 79.8;Syncytiotrophoblasts: 77.2;Undifferentiated cells: 81.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA043491 Uncertain "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 10 "HPA043491: AB_2678510" "unprognostic (2.04e-2)" "unprognostic (2.53e-2)" "unprognostic (1.17e-1)" "unprognostic (4.02e-3)" "unprognostic (3.80e-1)" "unprognostic (7.44e-2)" "unprognostic (2.21e-1)" "unprognostic (3.10e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.51e-2)" "unprognostic (3.78e-9)" "unprognostic (3.52e-2)" "unprognostic (1.03e-1)" "unprognostic (7.37e-2)" "unprognostic (1.73e-3)" CKMT1B "CKMT, CKMT1, UMTCK" ENSG00000237289 "Creatine kinase, mitochondrial 1B" P12532 15 43593054-43604901 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.7;esophagus: 72.2;intestine: 78.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 109.4;Distal enterocytes: 198.6;Enteroendocrine cells: 79.9;Intestinal goblet cells: 75.9;Paneth cells: 69.9;Proximal enterocytes: 122.2;Syncytiotrophoblasts: 107.6;Undifferentiated cells: 93.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" HPA043491 Uncertain "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 10 "HPA043491: AB_2678510" "unprognostic (3.47e-2)" "unprognostic (9.73e-3)" "unprognostic (3.10e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (1.29e-1)" "unprognostic (1.96e-1)" "unprognostic (5.19e-2)" "unprognostic (2.84e-1)" "unprognostic (3.64e-1)" "unprognostic (5.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-2)" "unprognostic (2.26e-8)" "unprognostic (1.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.43e-2)" "unprognostic (4.36e-2)" CLCN2 "ClC-2, CLC2, EJM6" ENSG00000114859 "Chloride voltage-gated channel 2" P51788 3 184346185-184361650 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 17.2;Distal enterocytes: 76.3;Proximal enterocytes: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009397, HPA014545, HPA024108" Approved Approved Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Cytosol "CAB009397: AB_2079256, HPA014545: AB_1846881, HPA024108: AB_1846883" "unprognostic (1.13e-1)" "unprognostic (4.01e-2)" "unprognostic (6.48e-2)" "unprognostic (5.11e-3)" "unprognostic (1.15e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (4.67e-8)" "unprognostic (1.72e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-1)" "unprognostic (2.10e-1)" "unprognostic (2.50e-3)" "unprognostic (1.19e-1)" "unprognostic (4.40e-2)" "unprognostic (5.88e-2)" "unprognostic (4.60e-2)" "unprognostic (1.35e-1)" CLDN2 ENSG00000165376 "Claudin 2" P57739 X 106900164-106930861 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 194.7;gallbladder: 98.1;kidney: 159.3;seminal vesicle: 87.0" "Cell type enhanced" "Detected in some" "Ductal cells: 75.9;Exocrine glandular cells: 36.3;Hepatocytes: 25.7;Proximal enterocytes: 31.3;Proximal tubular cells: 88.4" "Group enriched" "Detected in many" 5 "colorectal cancer: 53.3;liver cancer: 24.6;pancreatic cancer: 48.5;renal cancer: 87.2;stomach cancer: 30.5" "Region enriched" "Detected in many" 13 "choroid plexus: 243.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 127.7;Kidney cancer: 98.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells" "Group enriched" "Detected in many" 4 "basal ganglia: 4.5;hippocampal formation: 9.5;pons and medulla: 10.3;thalamus: 8.9" "Low region specificity" "Detected in many" "CAB002609, HPA051548" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 16 "Nucleoplasm, Cell Junctions" "CAB002609: , HPA051548: AB_2681530" "unprognostic (2.31e-1)" "unprognostic (2.62e-1)" "unprognostic (3.99e-1)" "unprognostic (1.73e-1)" "unprognostic (1.30e-2)" "unprognostic (1.42e-2)" "unprognostic (6.07e-2)" "unprognostic (7.47e-3)" "unprognostic (2.24e-1)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (8.15e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (2.12e-1)" "prognostic favorable (1.70e-4)" "unprognostic (9.76e-2)" CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.9;stomach 1: 15.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 337.6;Gastric mucus-secreting cells: 61.9;Paneth cells: 183.6;Proximal enterocytes: 99.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 4 "choroid plexus: 4.6" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 5: Enterocytes - Absorption" 1 Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" CLDN3 "C7orf1, CPE-R2, CPETR2, HRVP1, RVP1" ENSG00000165215 "Claudin 3" O15551 7 73768997-73770270 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 255.8;thyroid gland: 112.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3382.2;Enteroendocrine cells: 1232.2;Glandular and luminal cells: 1710.6;Intestinal goblet cells: 1891.4;Paneth cells: 2536.5;Proximal enterocytes: 3236.9;Undifferentiated cells: 1191.8" "Cancer enhanced" "Detected in many" "ovarian cancer: 529.2" "Region enriched" "Detected in all" 8 "choroid plexus: 81.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 169.1" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric enteroendocrine cells, Testis - Sertoli cells" "Region enhanced" "Detected in single" "basal ganglia: 1.5" HPA014361 Enhanced Supported "Cell Junctions" NA NA "Cluster 45: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Cell Junctions" "HPA014361: AB_2668982" "unprognostic (1.84e-1)" "unprognostic (4.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.27e-2)" "unprognostic (2.61e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (8.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.28e-3)" "unprognostic (1.42e-1)" "prognostic favorable (3.39e-5)" "unprognostic (1.46e-2)" "unprognostic (1.87e-1)" "unprognostic (5.18e-2)" "unprognostic (6.72e-2)" CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 296.4;urinary bladder: 291.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2807.8;Glandular and luminal cells: 2344.4;Ionocytes: 1646.0;Paneth cells: 2199.5;Proximal enterocytes: 1639.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 992.2" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 14 "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 331.7;intestine: 331.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1489.3;Intestinal goblet cells: 761.2;Paneth cells: 878.8;Proximal enterocytes: 1331.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 61 Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" CLIC5 DFNB102 ENSG00000112782 "Chloride intracellular channel 5" Q9NZA1 6 45880827-46080348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Hearing, Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel, Voltage-gated channel" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 99.1;skeletal muscle: 279.4;tongue: 94.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 397.8;Cardiomyocytes: 248.7;Distal enterocytes: 93.6;Late spermatids: 105.5;Proximal enterocytes: 114.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 5.1" "Lineage enriched" "Detected in single" 17 "T-cells: 5.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.2;ovarian cancer: 13.8" "Breast - Endothelial cells, Kidney - Podocytes, Lung - Alveolar cells type 1, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074371 Supported "Nuclear speckles,Plasma membrane" NA NA 400000 "Cluster 1: T-cells - Unknown function" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" "Plasma membrane" "Nuclear speckles" "HPA074371: " "unprognostic (4.95e-2)" "unprognostic (1.59e-2)" "unprognostic (8.84e-2)" "unprognostic (5.05e-2)" "unprognostic (2.44e-1)" "unprognostic (6.73e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (6.46e-2)" "unprognostic (5.50e-2)" "unprognostic (3.65e-1)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.99e-1)" "unprognostic (8.26e-2)" "unprognostic (1.01e-1)" CMBL FLJ23617 ENSG00000164237 "Carboxymethylenebutenolidase homolog" Q96DG6 5 10275875-10307902 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 162.1;liver: 166.8;skeletal muscle: 158.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 245.8;Hepatocytes: 197.3;Proximal enterocytes: 765.0;Proximal tubular cells: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036571 Uncertain NA NA 580000 "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" "HPA036571: AB_10670114" "unprognostic (1.81e-2)" "unprognostic (2.55e-1)" "unprognostic (8.10e-3)" "unprognostic (2.53e-2)" "unprognostic (2.01e-1)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.20e-1)" "unprognostic (8.64e-2)" "prognostic favorable (1.99e-4)" "unprognostic (1.76e-1)" "unprognostic (4.44e-2)" "unprognostic (1.29e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.52e-1)" "unprognostic (2.44e-1)" CNDP2 "CN2, CPGL, FLJ10830, HsT2298, PEPA" ENSG00000133313 "Carnosine dipeptidase 2" Q96KP4 18 74495816-74523454 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 330.3;Proximal enterocytes: 618.8;Proximal tubular cells: 436.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026196, HPA036898, HPA036899" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 2600000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Kidney - Transmembrane transport" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoplasm, Cytosol" "CAB026196: , HPA036898: AB_2675370, HPA036899: AB_2675371" "unprognostic (2.81e-2)" "unprognostic (9.96e-2)" "unprognostic (3.28e-1)" "unprognostic (1.19e-3)" "unprognostic (2.57e-2)" "unprognostic (5.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.49e-1)" "unprognostic (9.31e-2)" "unprognostic (1.56e-3)" "unprognostic (1.15e-1)" "prognostic favorable (3.50e-6)" "unprognostic (2.37e-3)" "unprognostic (4.65e-3)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" COMTD1 FLJ23841 ENSG00000165644 "Catechol-O-methyltransferase domain containing 1" Q86VU5 10 75233641-75236030 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 124.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 276.9;Proximal enterocytes: 431.5;Squamous epithelial cells: 283.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042165 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA042165: AB_10794042" "unprognostic (2.53e-2)" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (9.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (3.23e-2)" "unprognostic (8.08e-3)" "unprognostic (9.35e-2)" "unprognostic (6.74e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.12e-1)" "unprognostic (2.35e-1)" COQ4 CGI-92 ENSG00000167113 "Coenzyme Q4" Q9Y3A0 9 128322544-128334072 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 198.6;Proximal tubular cells: 194.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021406, HPA042945" Supported Supported Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 17: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 22: Proximal enterocytes - Digestion" 7 Mitochondria "HPA021406: AB_2670691, HPA042945: AB_10961047" "unprognostic (9.15e-2)" "prognostic favorable (2.97e-5)" "unprognostic (2.29e-1)" "prognostic favorable (4.93e-6)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (7.51e-2)" "unprognostic (2.11e-1)" "unprognostic (1.31e-3)" "unprognostic (2.89e-2)" "prognostic favorable (5.76e-6)" "unprognostic (6.21e-3)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (5.14e-3)" CORO1B coronin-2 ENSG00000172725 "Coronin 1B" Q9BR76 11 67435510-67443821 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 294.1;Extravillous trophoblasts: 260.9;Proximal enterocytes: 267.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 222.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Lung - Macrophages, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017616, HPA040113, HPA070456" Enhanced Supported "Plasma membrane,Cytosol" NA NA 960000 "Cluster 40: Monocytes - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" 6 "Plasma membrane, Cytosol" "CAB017616: AB_2087018, HPA040113: AB_2676850, HPA070456: AB_2686268" "unprognostic (1.94e-1)" "unprognostic (2.40e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.65e-4)" "unprognostic (1.02e-1)" "unprognostic (8.23e-3)" "unprognostic (1.49e-3)" "unprognostic (7.22e-2)" "unprognostic (1.86e-1)" "unprognostic (4.86e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-2)" "unprognostic (8.58e-3)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (1.21e-2)" "unprognostic (6.64e-3)" CORO2A "IR10, WDR2" ENSG00000106789 "Coronin 2A" Q92828 9 98120975-98192637 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 48.2;Club cells: 48.2;Distal enterocytes: 79.2;Ionocytes: 48.6;Proximal enterocytes: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 11.4;monocytes: 7.8;T-cells: 11.9" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041161, HPA041302" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 45: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 3 "Plasma membrane, Cytosol" "HPA041161: AB_10795537, HPA041302: AB_10794195" "unprognostic (4.49e-3)" "unprognostic (3.44e-2)" "unprognostic (3.14e-1)" "unprognostic (1.78e-1)" "unprognostic (3.39e-3)" "unprognostic (1.64e-1)" "unprognostic (3.73e-2)" "unprognostic (5.73e-2)" "unprognostic (2.79e-1)" "unprognostic (1.52e-1)" "unprognostic (4.50e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" "unprognostic (6.40e-3)" COX5B ENSG00000135940 "Cytochrome c oxidase subunit 5B" P10606 2 97646062-97648383 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1114.8;skeletal muscle: 1286.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 6557.4;Distal enterocytes: 3170.5;Distal tubular cells: 3405.4;Proximal enterocytes: 2823.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034517 Supported Enhanced Mitochondria NA NA 230000 "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 39: Non-specific - Basic cellular processes" 29 Mitochondria "HPA034517: AB_10603561" "unprognostic (4.61e-2)" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-2)" "unprognostic (2.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (3.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.73e-4)" COX6A1 "COX6A, COX6AL" ENSG00000111775 "Cytochrome c oxidase subunit 6A1" P12074 12 120438090-120440737 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1660.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 2004.4;Proximal enterocytes: 1967.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062394 Approved Supported Mitochondria NA NA 85000 "Cluster 13: Non-specific - Mitochondria" "Cluster 33: Brain - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 2 Mitochondria "HPA062394: AB_2684749" "unprognostic (1.18e-1)" "unprognostic (1.03e-2)" "unprognostic (5.10e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-1)" "unprognostic (8.78e-2)" "unprognostic (3.33e-1)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (1.13e-2)" "unprognostic (3.22e-2)" "unprognostic (2.82e-1)" "prognostic favorable (6.50e-7)" "unprognostic (2.53e-1)" "unprognostic (1.31e-1)" "unprognostic (5.48e-2)" "unprognostic (2.63e-2)" CPTP "GLTPD1, MGC10334" ENSG00000224051 "Ceramide-1-phosphate transfer protein" Q5TA50 1 1324756-1328896 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 98.7;Early spermatids: 75.7;Late spermatids: 150.5;Proximal enterocytes: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA056832 Approved Approved Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 5: Enterocytes - Absorption" Cytosol "HPA056832: AB_2683251" "unprognostic (9.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (7.01e-2)" "unprognostic (1.94e-2)" "unprognostic (1.37e-1)" "unprognostic (1.90e-1)" "unprognostic (3.35e-1)" "unprognostic (1.52e-2)" "unprognostic (1.32e-2)" "unprognostic (2.79e-1)" "prognostic favorable (1.75e-4)" "unprognostic (1.27e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-2)" "unprognostic (5.27e-2)" CRAT CAT1 ENSG00000095321 "Carnitine O-acetyltransferase" P43155 9 129094142-129111189 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 219.5;tongue: 193.6" "Cell type enhanced" "Detected in many" "Early spermatids: 164.2;Late spermatids: 497.3;Proximal enterocytes: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019230, HPA020260, HPA022815" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 8100 "Cluster 33: Non-specific - ATP binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" "Golgi apparatus, Cytosol" "HPA019230: AB_1847212, HPA020260: AB_1847210, HPA022815: AB_2732427" "unprognostic (5.13e-2)" "unprognostic (9.79e-3)" "unprognostic (1.99e-2)" "prognostic favorable (2.36e-4)" "unprognostic (2.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-2)" "unprognostic (2.18e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-2)" "unprognostic (3.13e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.38e-1)" "unprognostic (9.27e-2)" "unprognostic (1.26e-2)" "unprognostic (7.65e-2)" CRIP1 CRIP ENSG00000213145 "Cysteine rich protein 1" P50238 14 105486317-105488947 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 1900.0;Proximal enterocytes: 2239.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042462 Approved Approved "Nuclear speckles,Plasma membrane,Centrosome,Cytosol" NA NA 29000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" "Nuclear speckles, Cytosol" "Plasma membrane, Centrosome" "HPA042462: AB_10794277" "unprognostic (2.97e-3)" "unprognostic (1.27e-3)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.39e-1)" "unprognostic (2.93e-3)" "unprognostic (4.33e-1)" "unprognostic (3.33e-1)" "unprognostic (3.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.87e-1)" "unprognostic (9.16e-2)" "unprognostic (3.26e-3)" "unprognostic (5.10e-2)" "unprognostic (2.66e-1)" "unprognostic (7.51e-3)" "unprognostic (2.14e-1)" CRYL1 "GDH, lambda-CRY, MGC149525, MGC149526" ENSG00000165475 "Crystallin lambda 1" Q9Y2S2 13 20403666-20525873 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 317.6;liver: 246.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 316.6;Hepatocytes: 334.2;Paneth cells: 265.7;Proximal enterocytes: 572.9;Proximal tubular cells: 736.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040403, HPA058848" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA 690000 "Cluster 33: Non-specific - ATP binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Nucleoplasm, Nucleoli" "Golgi apparatus, Plasma membrane" "HPA040403: AB_10795632, HPA058848: " "unprognostic (1.84e-1)" "unprognostic (1.25e-1)" "unprognostic (3.25e-2)" "prognostic favorable (1.76e-5)" "unprognostic (3.10e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-3)" "unprognostic (4.75e-3)" "unprognostic (1.19e-1)" "unprognostic (4.09e-2)" "unprognostic (2.12e-2)" "unprognostic (8.80e-2)" "prognostic favorable (2.30e-9)" "unprognostic (9.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (3.11e-1)" CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 356.8" "Cell type enhanced" "Detected in all" "Distal enterocytes: 353.1;Hofbauer cells: 295.6;Proximal enterocytes: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" Enzyme NA NA 28000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 57: Platelets - Hemostasis" 2 Vesicles "CAB024930: , HPA031068: AB_10601205, HPA072487: " "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" CTSD "CLN10, CPSD" ENSG00000117984 "Cathepsin D" P07339 11 1752752-1764573 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Aspartyl protease, Hydrolase, Protease" "Alzheimer disease, Cancer-related genes, Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1368.7;Hofbauer cells: 3533.1;Macrophages: 1286.5;Proximal enterocytes: 1589.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000109, HPA003001" Supported "Secreted to blood" Enzyme NA NA 370000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" 22 "CAB000109: , HPA003001: AB_1078404" "unprognostic (9.95e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (2.46e-4)" "unprognostic (1.09e-1)" "unprognostic (1.71e-3)" "unprognostic (2.65e-2)" "unprognostic (9.40e-3)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (1.12e-3)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.93e-5)" "unprognostic (8.98e-2)" "unprognostic (3.39e-2)" "unprognostic (2.13e-2)" "unprognostic (1.60e-1)" CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 51.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 235.9;Proximal enterocytes: 218.0;Suprabasal keratinocytes: 220.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Secreted - unknown location" Receptor NA NA 18000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 12: Squamous epithelial cells - Keratinization" 2 "Plasma membrane, Cell Junctions" Nucleoplasm "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2392.7" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 2106.5;Distal tubular cells: 1512.1;Hepatocytes: 3946.9;Proximal enterocytes: 1904.2;Proximal tubular cells: 2759.2" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skeletal muscle - Fibroblasts, Skin - Sebaceous gland cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 34: B-cells - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 43: Hepatocytes - Metabolism" 3 "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 229.2;Leydig cells: 193.7;Peritubular cells: 215.1;Proximal enterocytes: 691.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.8;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.8" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 19 "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 99.8;liver: 191.1;stomach 1: 65.5" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 61.9;Hepatocytes: 109.4;Proximal enterocytes: 54.2;Squamous epithelial cells: 27.9;Suprabasal keratinocytes: 62.5" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 13.3;liver cancer: 4.0" "Colon - Colon enterocytes, Liver - Hepatocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 59: Suprabasal keratinocytes - Cornification" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 172.8;liver: 269.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 396.8;Distal enterocytes: 264.5;Gastric mucus-secreting cells: 525.3;Hepatocytes: 410.7;Proximal enterocytes: 1064.2" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Colon - Colon enterocytes, Liver - Hepatocytes, Stomach - Gastric mucous cells" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" CYP4F11 ENSG00000171903 "Cytochrome P450 family 4 subfamily F member 11" Q9HBI6 19 15912367-15934867 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.1;liver: 70.5" "Cell type enhanced" "Detected in many" "Ductal cells: 15.0;Hepatocytes: 56.3;Proximal enterocytes: 13.5" "Cancer enhanced" "Detected in many" "liver cancer: 25.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 217.7" "Liver - Hepatocytes" "HPA017265, CAB033648, HPA058960" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 1 "CAB033648: AB_2088410, HPA017265: AB_1847451, HPA058960: AB_2683862" "prognostic favorable (4.05e-4)" "unprognostic (4.12e-2)" "unprognostic (1.79e-1)" "unprognostic (5.99e-2)" "unprognostic (5.92e-3)" "unprognostic (1.06e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-1)" "unprognostic (2.33e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (9.28e-4)" "unprognostic (4.44e-2)" "unprognostic (9.50e-3)" "unprognostic (2.14e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-2)" "unprognostic (4.64e-2)" CYP4F12 ENSG00000186204 "Cytochrome P450 family 4 subfamily F member 12" Q9HCS2 19 15673018-15697174 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 40.4;liver: 39.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.5;Gastric mucus-secreting cells: 57.8;Paneth cells: 45.3;Proximal enterocytes: 113.7;Suprabasal keratinocytes: 40.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 54 "basophil: 6.2;eosinophil: 14.9" "Lineage enriched" "Detected in single" 88 "granulocytes: 14.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 5.0;Gastric cancer: 5.6" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Urothelial cells, Thyroid - Fibroblasts" HPA058960 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA058960: AB_2683862" "unprognostic (4.30e-4)" "prognostic favorable (1.21e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-2)" "unprognostic (5.32e-3)" "unprognostic (1.84e-3)" "unprognostic (9.13e-2)" "unprognostic (9.11e-2)" "unprognostic (2.50e-1)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-3)" "unprognostic (6.20e-2)" "unprognostic (5.45e-2)" "unprognostic (3.17e-1)" "prognostic favorable (2.33e-4)" DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 48.4;thyroid gland: 40.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 91.4;Late spermatids: 111.3;Oligodendrocytes: 92.9;Proximal enterocytes: 53.4" "Cancer enriched" "Detected in many" 15 "thyroid cancer: 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "basophil: 64.8;eosinophil: 138.6;neutrophil: 39.2" "Lineage enriched" "Detected in many" 26 "granulocytes: 138.6" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 63: Late spermatids - Spermatogenesis" 1 "Golgi apparatus, Vesicles" "HPA071581: AB_2686421" "unprognostic (3.20e-2)" "unprognostic (4.07e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-3)" "unprognostic (2.88e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "prognostic favorable (5.63e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (8.51e-2)" "unprognostic (4.77e-7)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-3)" "unprognostic (9.07e-2)" DCAF11 "GL014, PRO2389, WDR23" ENSG00000100897 "DDB1 and CUL4 associated factor 11" Q8TEB1 14 24114195-24125242 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 125.0;Hepatocytes: 147.4;Proximal enterocytes: 142.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003583, HPA031157" Approved Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 1: Erythroid cells - Oxygen transport" 9 Nucleoplasm "HPA003583: AB_2667001, HPA031157: AB_10603002" "unprognostic (1.50e-1)" "unprognostic (4.72e-2)" "unprognostic (3.22e-1)" "unprognostic (8.45e-2)" "unprognostic (1.01e-1)" "unprognostic (9.58e-2)" "unprognostic (1.91e-3)" "unprognostic (1.48e-3)" "unprognostic (3.23e-2)" "unprognostic (4.08e-1)" "unprognostic (1.19e-1)" "unprognostic (2.01e-1)" "prognostic favorable (3.50e-13)" "unprognostic (2.58e-1)" "unprognostic (3.48e-1)" "unprognostic (6.80e-2)" "unprognostic (1.68e-1)" DDO "DASOX, DASPO" ENSG00000203797 "D-aspartate oxidase" Q99489 6 110391771-110415575 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 17.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 19.3;Muller glia cells: 7.6;Oligodendrocytes: 12.3;Proximal enterocytes: 8.8;Proximal tubular cells: 9.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 3.3;myeloid DC: 4.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Rhabdoid: 5.8" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037525, HPA037526" Enhanced Enhanced Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Macrophages - Innate immune response" Cytosol "HPA037525: AB_2675523, HPA037526: AB_10672352" "unprognostic (1.37e-1)" "unprognostic (1.54e-1)" "unprognostic (6.51e-2)" "unprognostic (1.30e-2)" "unprognostic (2.00e-1)" "unprognostic (3.28e-2)" "unprognostic (3.71e-2)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (2.91e-1)" "unprognostic (6.97e-2)" "unprognostic (1.43e-1)" "prognostic favorable (8.69e-5)" "unprognostic (3.51e-4)" "unprognostic (3.36e-3)" "unprognostic (1.27e-3)" "unprognostic (9.06e-2)" DDT "D-DT, DDCT, MIF-2, MIF2" ENSG00000099977 "D-dopachrome tautomerase" P30046 22 23970542-23980525 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Melanin biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 815.7" "Cell type enhanced" "Detected in all" "Distal enterocytes: 259.1;Hepatocytes: 394.8;Proximal enterocytes: 400.6;Proximal tubular cells: 202.2;Undifferentiated cells: 211.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "HPA049871, HPA074115" Enhanced Approved Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 43: Hepatocytes - Metabolism" Mitochondria "HPA049871: AB_2680926, HPA074115: " "unprognostic (1.77e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (8.09e-2)" "unprognostic (4.00e-3)" "unprognostic (2.02e-3)" "unprognostic (6.58e-2)" "unprognostic (4.66e-2)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-3)" "unprognostic (1.12e-1)" "unprognostic (7.34e-2)" "unprognostic (3.30e-1)" "unprognostic (3.81e-1)" "unprognostic (2.61e-3)" DDTL ENSG00000099974 "D-dopachrome tautomerase like" A6NHG4 22 23966888-23972556 "Predicted intracellular proteins" Lyase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 57.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 6.4;Proximal enterocytes: 7.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "basophil: 1.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.0" "Low cancer specificity" "Detected in some" HPA074115 Approved NA NA "Cluster 83: Liver - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 49: Non-specific - Transcription" "HPA074115: " "unprognostic (6.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.91e-1)" "unprognostic (6.34e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "prognostic favorable (5.98e-4)" "unprognostic (2.65e-2)" "unprognostic (2.26e-2)" "unprognostic (1.60e-1)" "unprognostic (1.77e-2)" "unprognostic (2.18e-1)" "unprognostic (5.74e-2)" "unprognostic (2.05e-2)" "unprognostic (1.46e-1)" "unprognostic (3.70e-2)" "unprognostic (3.58e-3)" DEGS2 "C14orf66, DES2, FADS8" ENSG00000168350 "Delta 4-desaturase, sphingolipid 2" Q6QHC5 14 100143957-100159645 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.0;intestine: 33.8;skin 1: 52.4" "Cell type enhanced" "Detected in many" "Oocytes: 95.6;Proximal enterocytes: 315.6;Squamous epithelial cells: 104.6;Suprabasal keratinocytes: 137.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 3.5;eosinophil: 6.7;memory B-cell: 10.9;naive B-cell: 6.9" "Group enriched" "Detected in many" 5 "B-cells: 10.9;granulocytes: 6.7" "Cancer enhanced" "Detected in many" "breast cancer: 20.5;colorectal cancer: 11.3;Gastric cancer: 11.7" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046644 Approved Nucleoplasm,Nucleoli NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 45: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoplasm, Nucleoli" "HPA046644: AB_2797231" "unprognostic (8.18e-2)" "unprognostic (3.83e-3)" "unprognostic (2.33e-1)" "unprognostic (1.32e-2)" "unprognostic (3.55e-1)" "unprognostic (4.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.13e-2)" "unprognostic (2.43e-1)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.94e-7)" "unprognostic (1.03e-3)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "prognostic favorable (1.66e-4)" DERA "CGI-26, DEOC" ENSG00000023697 "Deoxyribose-phosphate aldolase" Q9Y315 12 15911302-16037381 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 101.4" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 142.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055897 Supported Nucleoplasm NA NA 320000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 57: Platelets - Hemostasis" 2 Nucleoplasm "HPA055897: AB_2682963" "unprognostic (3.05e-1)" "unprognostic (1.26e-1)" "unprognostic (1.06e-2)" "unprognostic (7.26e-2)" "unprognostic (8.12e-2)" "unprognostic (7.74e-2)" "unprognostic (1.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (8.74e-2)" "unprognostic (2.17e-2)" "prognostic favorable (3.64e-5)" "unprognostic (3.66e-2)" DGKA "DAGK, DAGK1, DGK-alpha" ENSG00000065357 "Diacylglycerol kinase alpha" P23743 12 55927319-55954027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 98.6;lymphoid tissue: 193.0" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 42.9;Squamous epithelial cells: 43.1;T-cells: 49.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "T-cells: 87.0" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041645, HPA045462" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" Vesicles "Nucleoplasm, Mitochondria" "HPA041645: AB_2677595, HPA045462: AB_2679335" "unprognostic (1.12e-3)" "unprognostic (1.43e-2)" "unprognostic (1.62e-2)" "unprognostic (2.63e-2)" "unprognostic (5.23e-2)" "unprognostic (2.04e-1)" "unprognostic (3.62e-1)" "unprognostic (3.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.66e-5)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (1.47e-1)" "unprognostic (7.02e-2)" DGKQ "DAGK, DAGK4, DAGK7" ENSG00000145214 "Diacylglycerol kinase theta" P52824 4 958887-986895 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 30.6;Intestinal goblet cells: 25.6;Paneth cells: 24.0;Proximal enterocytes: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026797, CAB033835" Uncertain Approved Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 80: Non-specific - Endocytosis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 16: Intestinal goblet cells - Mucin production" 1 Nucleoli "CAB033835: AB_2091307, HPA026797: AB_10600902" "unprognostic (7.39e-2)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.64e-2)" "unprognostic (1.14e-1)" "unprognostic (5.08e-2)" "unprognostic (3.37e-1)" "unprognostic (6.39e-2)" "unprognostic (2.90e-2)" "unprognostic (1.06e-1)" "unprognostic (6.45e-2)" "unprognostic (1.06e-2)" "unprognostic (9.77e-2)" "unprognostic (3.08e-3)" "unprognostic (4.38e-2)" "unprognostic (2.65e-2)" "unprognostic (1.65e-3)" DHRS1 "FLJ25430, MGC20204, SDR19C1" ENSG00000157379 "Dehydrogenase/reductase 1" Q96LJ7 14 24290598-24299780 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 66.9;liver: 59.4" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 175.7;Suprabasal keratinocytes: 161.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000599, HPA076886" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 25 Nucleoplasm "Centrosome, Cytosol" "HPA000599: AB_1078655, HPA076886: " "unprognostic (2.08e-3)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (2.75e-1)" "unprognostic (3.57e-1)" "unprognostic (6.57e-2)" "prognostic favorable (1.18e-5)" "prognostic favorable (6.83e-4)" "unprognostic (3.66e-1)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (9.88e-2)" "unprognostic (2.25e-3)" "unprognostic (1.32e-2)" "unprognostic (1.58e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-1)" DHRS4L2 SDR25C3 ENSG00000187630 "Dehydrogenase/reductase 4 like 2" Q6PKH6 14 23969874-24006408 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 102.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 203.7;Proximal enterocytes: 335.6;Proximal tubular cells: 460.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Secreted - unknown location" Enzyme NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (1.41e-2)" "unprognostic (2.83e-3)" "unprognostic (1.25e-1)" "unprognostic (2.68e-2)" "unprognostic (1.47e-1)" "unprognostic (2.53e-1)" "unprognostic (6.02e-2)" "unprognostic (3.97e-3)" "unprognostic (7.34e-2)" "prognostic favorable (3.21e-4)" "unprognostic (1.57e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-3)" "unprognostic (6.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (3.65e-2)" DHRS7 "retDSR4, SDR34C1" ENSG00000100612 "Dehydrogenase/reductase 7" Q9Y394 14 60144119-60169856 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 594.0" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 1021.8;Proximal enterocytes: 836.1;Serous glandular cells: 508.0" "Cancer enriched" "Detected in all" 5 "prostate cancer: 199.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Macrophages, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031121, HPA078401" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 2 "Nucleoplasm, Mitochondria" "HPA031121: AB_10600803, HPA078401: " "prognostic favorable (6.42e-4)" "unprognostic (5.20e-2)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (4.65e-2)" "unprognostic (4.31e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.92e-10)" "unprognostic (8.35e-3)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" DMAC2 "ATP5SL, FLJ10241" ENSG00000105341 "Distal membrane arm assembly component 2" Q9NW81 19 41431318-41440717 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041427 Approved Approved Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "HPA041427: AB_2677473" "unprognostic (1.42e-3)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.20e-1)" "unprognostic (6.88e-3)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.77e-4)" "unprognostic (4.37e-1)" "unprognostic (3.83e-2)" "unprognostic (1.18e-2)" "unprognostic (1.52e-2)" "unprognostic (2.10e-1)" "prognostic favorable (4.07e-5)" "unprognostic (5.20e-2)" "unprognostic (2.48e-1)" "unprognostic (6.60e-2)" "unprognostic (7.29e-3)" DNPEP "ASPEP, DAP" ENSG00000123992 "Aspartyl aminopeptidase" Q9ULA0 2 219372043-219400022 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 299.0;Late spermatids: 497.7;Proximal enterocytes: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036398, HPA044860" Enhanced Supported Cytosol NA NA 2700000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 11: Late spermatids - Unknown function" 2 Cytosol "HPA036398: AB_10970915, HPA044860: AB_10961275" "unprognostic (3.71e-1)" "unprognostic (6.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.75e-1)" "unprognostic (2.54e-3)" "unprognostic (3.34e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" "unprognostic (1.61e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-1)" "unprognostic (5.63e-3)" "unprognostic (3.49e-1)" "unprognostic (2.50e-1)" "unprognostic (1.85e-3)" DNPH1 "C6orf108, dJ330M21.3, rcl" ENSG00000112667 "2'-deoxynucleoside 5'-phosphate N-hydrolase 1" O43598 6 43225629-43229481 "Predicted intracellular proteins" "Nucleotide metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 831.7;Proximal tubular cells: 1006.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029675, HPA029676" Enhanced Approved Nucleoplasm,Cytosol No No 540000 "Cluster 33: Non-specific - ATP binding" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 22: Proximal enterocytes - Digestion" 5 Nucleoplasm Cytosol "HPA029675: AB_10599998, HPA029676: AB_10599424" "unprognostic (1.12e-2)" "unprognostic (1.38e-1)" "unprognostic (4.03e-3)" "unprognostic (8.24e-3)" "unprognostic (1.69e-1)" "unprognostic (3.53e-2)" "unprognostic (2.61e-1)" "unprognostic (7.72e-2)" "unprognostic (2.43e-1)" "unprognostic (2.33e-3)" "unprognostic (2.25e-2)" "unprognostic (1.49e-1)" "unprognostic (1.74e-1)" "unprognostic (5.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.77e-2)" "unprognostic (5.10e-2)" DOK4 FLJ10488 ENSG00000125170 "Docking protein 4" Q8TEW6 16 57471922-57487327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 98.3;Paneth cells: 70.4;Proximal enterocytes: 88.3;Proximal tubular cells: 43.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Neuroblastoma: 186.7" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008348, HPA055849" Supported Approved Cytosol NA No "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 5: Enterocytes - Absorption" 8 Cytosol "HPA008348: , HPA055849: AB_2682942" "unprognostic (3.44e-2)" "unprognostic (2.04e-2)" "unprognostic (1.17e-1)" "unprognostic (4.73e-2)" "unprognostic (3.66e-1)" "unprognostic (9.71e-2)" "unprognostic (5.35e-2)" "unprognostic (1.39e-1)" "unprognostic (1.13e-2)" "unprognostic (3.00e-2)" "unprognostic (2.27e-2)" "unprognostic (1.53e-1)" "unprognostic (2.58e-3)" "unprognostic (4.30e-2)" "unprognostic (2.21e-1)" "unprognostic (4.42e-3)" "unprognostic (1.18e-3)" DOLPP1 LSFR2 ENSG00000167130 "Dolichyldiphosphatase 1" Q86YN1 9 129081111-129090438 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019179 Approved Approved "Vesicles,Intermediate filaments" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" Vesicles "Intermediate filaments" "HPA019179: AB_1847827" "unprognostic (1.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.89e-1)" "unprognostic (6.12e-3)" "unprognostic (3.11e-1)" "unprognostic (2.63e-2)" "unprognostic (3.18e-1)" "unprognostic (3.10e-2)" "unprognostic (6.96e-2)" "unprognostic (7.12e-2)" "unprognostic (1.65e-1)" "unprognostic (4.37e-3)" "unprognostic (7.59e-3)" "unprognostic (2.38e-2)" "unprognostic (1.35e-1)" "unprognostic (4.69e-2)" "unprognostic (5.34e-2)" DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992245-162074394 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 134.2;parathyroid gland: 151.0;placenta: 129.7;prostate: 103.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 135.0;Prostatic glandular cells: 195.7;Proximal enterocytes: 277.2;Serous glandular cells: 142.3;Syncytiotrophoblasts: 167.3" "Cancer enhanced" "Detected in all" "prostate cancer: 55.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 52.4" "Lineage enriched" "Detected in many" 10 "T-cells: 52.4" "Cancer enhanced" "Detected in many" "Kidney cancer: 54.4" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Fibroblast_2, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045970, HPA068778, HPA071236" Enhanced "Secreted to blood" Receptor NA NA 190000000 "Cluster 1: T-cells - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" 6 "CAB045970: AB_11140529, HPA068778: , HPA071236: " "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.98e-4)" "prognostic favorable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favorable (4.99e-4)" "unprognostic (1.21e-2)" DYNC2I2 "bA216B9.3, CFAP133, DIC5, FAP133, MGC20486, WDR34" ENSG00000119333 "Dynein 2 intermediate chain 2" Q96EX3 9 128633653-128656847 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 217.8;Proximal enterocytes: 157.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 35.9;naive B-cell: 53.2" "Lineage enriched" "Detected in all" 5 "B-cells: 53.2" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040764, HPA041091" Approved Approved Cytosol NA Yes "Cluster 17: B-cells - Immunoglobulins" "Cluster 78: Testis - Transcription" "Cluster 3: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium assembly" 11 Cytosol "HPA040764: AB_10795625, HPA041091: AB_10796237" "unprognostic (1.45e-1)" "prognostic favorable (1.63e-4)" "unprognostic (2.55e-1)" "prognostic favorable (7.01e-5)" "unprognostic (2.27e-1)" "unprognostic (7.00e-3)" "prognostic unfavorable (8.79e-4)" "unprognostic (6.04e-2)" "unprognostic (4.39e-1)" "unprognostic (3.65e-1)" "unprognostic (8.55e-2)" "unprognostic (1.04e-1)" "unprognostic (3.57e-3)" "unprognostic (2.06e-2)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" EDF1 "CFAP280, EDF-1" ENSG00000107223 "Endothelial differentiation related factor 1" O60869 9 136862119-136866308 "Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Activator, Calmodulin-binding, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 2669.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035642 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" 6 "Nucleoplasm, Cytosol" "HPA035642: AB_10611959" "unprognostic (2.07e-1)" "unprognostic (1.25e-2)" "unprognostic (3.97e-2)" "unprognostic (3.58e-3)" "unprognostic (4.49e-2)" "unprognostic (2.32e-1)" "unprognostic (9.05e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (4.03e-2)" "unprognostic (2.65e-2)" "unprognostic (9.76e-2)" "unprognostic (1.83e-1)" "unprognostic (2.08e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" EDN2 ET2 ENSG00000127129 "Endothelin 2" P20800 1 41478775-41484683 "Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 25.4;esophagus: 20.2;vagina: 31.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 143.6;Club cells: 135.7;Collecting duct cells: 72.0;Ionocytes: 104.2;Proximal enterocytes: 83.1;Secretory cells: 57.5" "Cancer enhanced" "Detected in many" "cervical cancer: 24.0" "Region enriched" "Detected in single" 7 "choroid plexus: 2.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 30.6;Uterine cancer: 24.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA028459 Uncertain Approved Cytosol "Secreted to blood" Other NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" Cytosol "HPA028459: AB_10602490" "unprognostic (2.71e-2)" "unprognostic (5.64e-2)" "unprognostic (8.39e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.47e-2)" "unprognostic (3.87e-1)" "unprognostic (2.66e-2)" "unprognostic (1.04e-1)" "unprognostic (5.44e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (5.81e-4)" "unprognostic (5.59e-2)" "unprognostic (1.28e-2)" "unprognostic (8.47e-2)" "unprognostic (1.76e-1)" "unprognostic (6.14e-2)" "unprognostic (3.85e-1)" EDN3 ET3 ENSG00000124205 "Endothelin 3" P14138 20 59300443-59325992 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Deafness, Disease variant, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 51.7;salivary gland: 66.3;vagina: 103.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 86.4;Distal enterocytes: 72.0;Paneth cells: 69.9;Proximal enterocytes: 91.7;Squamous epithelial cells: 64.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 19.1;Uterine cancer: 25.7" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" Other NA NA 30900 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 19: Astrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 5: Enterocytes - Absorption" "unprognostic (4.64e-3)" "unprognostic (7.87e-2)" "unprognostic (7.49e-2)" "unprognostic (2.88e-3)" "prognostic favorable (1.73e-4)" "unprognostic (1.58e-1)" "unprognostic (1.78e-2)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (4.01e-2)" "unprognostic (4.08e-2)" "unprognostic (4.48e-1)" "unprognostic (6.11e-2)" "unprognostic (1.55e-1)" "unprognostic (6.40e-2)" EFHD2 MGC4342 ENSG00000142634 "EF-hand domain family member D2" Q96C19 1 15409888-15430339 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 444.7;NK-cells: 481.5;Proximal enterocytes: 290.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 133.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Macrophages, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048961 Enhanced Approved Cytosol No No 220000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Cytosol "HPA048961: AB_2680572" "unprognostic (1.37e-3)" "unprognostic (3.69e-1)" "unprognostic (7.83e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (9.11e-2)" "unprognostic (9.61e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "prognostic unfavorable (6.31e-9)" "unprognostic (2.71e-2)" "unprognostic (9.71e-2)" "prognostic favorable (2.70e-4)" "prognostic favorable (3.60e-5)" EIF4EBP3 4E-BP3 ENSG00000243056 "Eukaryotic translation initiation factor 4E binding protein 3" O60516 5 140547662-140549576 "Metabolic proteins, Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 59.6;Exocrine glandular cells: 18.8;Gastric mucus-secreting cells: 27.1;Proximal enterocytes: 25.1;Squamous epithelial cells: 36.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "prostate cancer: 38.6" "Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045537 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 49: Non-specific - Transcription" 2 "HPA045537: AB_10965796" "unprognostic (7.29e-2)" "unprognostic (4.20e-2)" "unprognostic (1.14e-1)" "unprognostic (2.44e-1)" "unprognostic (6.64e-2)" "unprognostic (4.84e-3)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (2.57e-1)" "unprognostic (8.36e-2)" "unprognostic (4.87e-3)" "unprognostic (2.17e-1)" "prognostic favorable (3.10e-4)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (8.82e-2)" "unprognostic (3.75e-1)" ELF3 "EPR-1, ERT, ESE-1, ESX" ENSG00000163435 "E74 like ETS transcription factor 3" P78545 1 202007945-202017183 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Inflammatory response, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 230.3" "Cell type enhanced" "Detected in many" "Club cells: 1496.5;Distal enterocytes: 1895.7;Gastric mucus-secreting cells: 1279.3;Intestinal goblet cells: 1476.0;Ionocytes: 2338.8;Paneth cells: 1327.5;Proximal enterocytes: 1397.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "HPA003316, HPA003479" Enhanced Enhanced Nucleoplasm NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 2 Nucleoplasm "HPA003316: AB_1078757, HPA003479: AB_1078756" "unprognostic (9.90e-3)" "unprognostic (1.72e-1)" "unprognostic (7.50e-2)" "unprognostic (1.12e-1)" "unprognostic (2.96e-3)" "unprognostic (3.88e-2)" "unprognostic (1.38e-2)" "unprognostic (1.83e-1)" "unprognostic (1.69e-1)" "unprognostic (5.05e-3)" "unprognostic (7.67e-3)" "unprognostic (7.07e-2)" "unprognostic (9.92e-3)" "unprognostic (4.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.85e-1)" "unprognostic (3.37e-3)" ELMO3 "CED-12, CED12, ELMO-3, FLJ13824" ENSG00000102890 "Engulfment and cell motility 3" Q96BJ8 16 67199111-67204029 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 74.9;Proximal enterocytes: 95.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021484 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane, Cell Junctions" "HPA021484: AB_1848129" "unprognostic (4.49e-3)" "unprognostic (2.04e-1)" "unprognostic (1.10e-2)" "unprognostic (8.08e-2)" "unprognostic (1.39e-1)" "unprognostic (6.16e-3)" "unprognostic (3.14e-1)" "unprognostic (8.17e-3)" "unprognostic (1.73e-1)" "unprognostic (8.06e-2)" "unprognostic (3.40e-2)" "unprognostic (6.95e-3)" "prognostic favorable (2.77e-5)" "unprognostic (3.47e-1)" "unprognostic (2.66e-1)" "unprognostic (1.84e-1)" "unprognostic (1.97e-2)" EMB MGC71745 ENSG00000170571 Embigin Q6PCB8 5 50396192-50443248 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 168.7" "Cell type enhanced" "Detected in many" "dendritic cells: 114.9;Macrophages: 110.8;Mesothelial cells: 104.7;NK-cells: 156.8;Proximal enterocytes: 127.0;T-cells: 160.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Heart muscle - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "unprognostic (1.01e-3)" "unprognostic (8.65e-2)" "unprognostic (1.66e-2)" "unprognostic (1.15e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-2)" "unprognostic (8.31e-2)" "unprognostic (2.71e-1)" "unprognostic (1.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.49e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (2.76e-5)" "unprognostic (4.96e-3)" "unprognostic (1.79e-1)" "unprognostic (1.22e-2)" "unprognostic (8.86e-3)" ENSG00000249141 ENSG00000249141 "Novel protein" 6 166858094-166956124 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "pancreas: 3.4" "Cell type enhanced" "Detected in some" "dendritic cells: 6.0;Distal enterocytes: 3.9;Hofbauer cells: 4.9;monocytes: 4.8;Paneth cells: 3.1;Proximal enterocytes: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 68: Non-specific - Protein processing" "Cluster 33: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 28: Dendritic cells - Antigen presentation" "unprognostic (1.22e-1)" "unprognostic (1.22e-1)" "unprognostic (7.52e-2)" "unprognostic (7.60e-2)" "unprognostic (1.51e-2)" "unprognostic (4.47e-2)" "unprognostic (7.13e-3)" "unprognostic (1.87e-1)" "unprognostic (2.27e-2)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (2.90e-3)" "unprognostic (1.76e-10)" "unprognostic (2.10e-1)" "unprognostic (1.24e-3)" "unprognostic (1.52e-1)" "unprognostic (9.28e-3)" ENSG00000276345 ENSG00000276345 Unmapped 2585-11802 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "choroid plexus: 34.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 64.5;Extravillous trophoblasts: 27.9;Proximal enterocytes: 52.6;Proximal tubular cells: 84.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA050406 Uncertain Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Nucleoli fibrillar center, Mitochondria" "HPA050406: AB_2681116" ENSG00000282988 ENSG00000282988 "Novel protein" 6 26195595-26199293 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 3.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.3;Paneth cells: 25.1;Prostatic glandular cells: 31.1;Proximal enterocytes: 29.7;Sertoli cells: 24.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 17.0;neutrophil: 30.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 30.6" "Low cancer specificity" "Detected in many" HPA041189 Uncertain Approved Nucleoplasm NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 61: Plasma cells - Immunoglobulins & histones" Nucleoplasm "HPA041189: AB_2677357" ENSG00000284976 ENSG00000284976 "Novel RING finger protein" 9 137217494-137219361 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 12.1;stomach 1: 12.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 39.6;Gastric mucus-secreting cells: 44.8;Intestinal goblet cells: 29.9;Proximal enterocytes: 40.3;Suprabasal keratinocytes: 43.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" ENSG00000285585 ENSG00000285585 "Novel protein" 3 119703076-119807570 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal enterocytes: 1.1;Proximal enterocytes: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA074084 Uncertain NA NA "Cluster 20: Myeloma - Immune response" "Cluster 45: Non-specific - Mixed function" "HPA074084: " ENTPD2 "CD39L1, NTPDase-2" ENSG00000054179 "Ectonucleoside triphosphate diphosphohydrolase 2" Q9Y5L3 9 137048107-137054061 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 197.4;Peritubular cells: 91.6;Proximal enterocytes: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 15.3" "Adipose subcutaneous - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017676 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "HPA017676: AB_1848179" "unprognostic (1.64e-1)" "unprognostic (3.35e-2)" "unprognostic (1.76e-1)" "unprognostic (3.33e-2)" "unprognostic (2.15e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.71e-2)" "unprognostic (4.97e-2)" "unprognostic (3.23e-1)" "unprognostic (2.99e-1)" "unprognostic (1.89e-1)" "prognostic favorable (3.51e-6)" "prognostic favorable (1.38e-4)" "unprognostic (2.51e-1)" "unprognostic (8.43e-2)" "unprognostic (1.12e-3)" ENTPD5 "CD39L4, NTPDase-5, PCPH" ENSG00000187097 "Ectonucleoside triphosphate diphosphohydrolase 5 (inactive)" O75356 14 73958010-74019399 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 103.8;kidney: 91.8;liver: 255.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 190.4;Hepatocytes: 115.5;Intestinal goblet cells: 86.4;Prostatic glandular cells: 78.6;Proximal enterocytes: 79.9" "Group enriched" "Detected in all" 5 "liver cancer: 18.2;prostate cancer: 39.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 18.4;eosinophil: 9.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 18.4" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002927 Enhanced "Secreted to blood" Enzyme NA NA 5900000 "Cluster 46: Basophils - Proteolysis" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 2 "HPA002927: AB_1078744" "unprognostic (4.19e-1)" "unprognostic (9.63e-3)" "unprognostic (3.11e-2)" "unprognostic (2.06e-2)" "unprognostic (1.98e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" "unprognostic (6.01e-2)" "unprognostic (6.20e-2)" "unprognostic (2.55e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.25e-1)" "unprognostic (5.06e-2)" "unprognostic (1.76e-1)" "unprognostic (6.92e-3)" EPB41L4B "EHM2, LULU2" ENSG00000095203 "Erythrocyte membrane protein band 4.1 like 4B" Q9H329 9 109171974-109321059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 86.2;pancreas: 144.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 134.2;Excitatory neurons: 77.0;Hepatocytes: 123.4;Proximal enterocytes: 73.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Stomach - Chief cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042862 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Plasma membrane, Cytosol" "HPA042862: AB_10794534" "prognostic unfavorable (1.02e-4)" "unprognostic (6.58e-2)" "unprognostic (2.33e-2)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-2)" "unprognostic (6.19e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (3.60e-1)" "unprognostic (6.20e-2)" "unprognostic (8.82e-4)" "unprognostic (1.46e-3)" "unprognostic (1.43e-1)" "unprognostic (4.65e-2)" "unprognostic (1.29e-1)" EPCAM "17-1A, 323/A3, Ber-Ep4, BerEp4, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC-31, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 780.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2590.4;Intestinal goblet cells: 1370.3;Paneth cells: 2221.3;Proximal enterocytes: 2597.5;Undifferentiated cells: 1520.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 762.9" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 5 "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" EPHX2 "ABHD20, sEH" ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490781-27545564 "Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 322.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 136.6;Proximal enterocytes: 401.7;Proximal tubular cells: 221.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 35.1;naive CD4 T-cell: 107.0;naive CD8 T-cell: 50.6;T-reg: 29.7" "Lineage enriched" "Detected in many" 23 "T-cells: 107.0" "Cancer enhanced" "Detected in all" "prostate cancer: 37.9" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 1100000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favorable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favorable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" EPN1 ENSG00000063245 "Epsin 1" Q9Y6I3 19 55675226-55709858 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 381.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009729, HPA061136, HPA071503" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 25: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" 5 "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB009729: AB_2277865, HPA061136: AB_2684436, HPA071503: " "unprognostic (6.93e-2)" "unprognostic (2.47e-1)" "unprognostic (5.30e-2)" "unprognostic (1.32e-1)" "unprognostic (7.94e-2)" "unprognostic (8.76e-2)" "unprognostic (1.23e-2)" "unprognostic (7.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (6.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (3.86e-3)" "unprognostic (1.57e-1)" "unprognostic (2.78e-3)" "unprognostic (7.92e-3)" EPS8L2 "FLJ21935, FLJ22171, MGC3088" ENSG00000177106 "EPS8 like 2" Q9H6S3 11 694438-727727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 183.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 164.6;Distal enterocytes: 140.0;Proximal enterocytes: 212.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Lung - Alveolar cells type 1, Skeletal muscle - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 10 "cerebellum: 12.2" HPA041143 Approved Supported Centrosome,Cytosol NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 5 "Centrosome, Cytosol" "HPA041143: AB_10794985" "unprognostic (1.39e-2)" "unprognostic (1.07e-1)" "unprognostic (7.58e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.87e-2)" "unprognostic (3.27e-2)" "unprognostic (1.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (2.54e-1)" "unprognostic (1.92e-1)" "unprognostic (3.25e-2)" "unprognostic (2.51e-2)" "unprognostic (4.19e-1)" "unprognostic (2.79e-1)" "unprognostic (5.03e-2)" EPSTI1 "BRESI1, MGC29634" ENSG00000133106 "Epithelial stromal interaction 1" Q96J88 13 42886388-42992271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 125.5;Extravillous trophoblasts: 188.8;Hofbauer cells: 88.4;Oocytes: 127.2;Proximal enterocytes: 105.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017362 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" "HPA017362: AB_1848226" "unprognostic (2.06e-1)" "unprognostic (3.51e-1)" "unprognostic (1.80e-1)" "unprognostic (3.59e-2)" "unprognostic (2.35e-1)" "unprognostic (9.55e-2)" "unprognostic (2.31e-1)" "unprognostic (2.49e-2)" "unprognostic (1.02e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.02e-5)" "unprognostic (7.90e-2)" "unprognostic (3.91e-2)" "unprognostic (1.05e-3)" "unprognostic (8.13e-2)" ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 207.6;Schwann cells: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" Receptor NA NA 450000 "Cluster 48: Stomach - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" 19 "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293638 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.4;esophagus: 15.0;lymphoid tissue: 10.4" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 18.7;Squamous epithelial cells: 8.1;Suprabasal keratinocytes: 11.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Mitotic cells (Lung), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 38: Non-specific - Transcription" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.01e-5)" "prognostic unfavorable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favorable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" ESPN DFNB36 ENSG00000187017 Espin B1AK53 1 6424776-6461367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing Actin-binding "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 125.7;retina: 114.4;testis: 140.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 176.1;Late spermatids: 476.6;Muller glia cells: 239.5;Paneth cells: 138.6;Proximal enterocytes: 514.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 29.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 92.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 4.0" "HPA028674, HPA060220" Enhanced Approved Vesicles NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA028674: AB_10601316, HPA060220: AB_2684224" "unprognostic (5.06e-2)" "unprognostic (1.18e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-1)" "unprognostic (2.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (2.28e-1)" "unprognostic (1.16e-1)" "unprognostic (5.71e-2)" "unprognostic (7.48e-3)" "unprognostic (5.53e-2)" "unprognostic (6.26e-3)" "unprognostic (5.51e-2)" "unprognostic (1.16e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-2)" ESRRA "ERR1, ERRa, ERRalpha, ESRL1, NR3B1" ENSG00000173153 "Estrogen related receptor alpha" P11474 11 64305497-64316743 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 188.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 162.0;Hepatocytes: 249.3;Kupffer cells: 167.7;Proximal enterocytes: 181.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053785, HPA077297" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Cytokinetic bridge" Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 35: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 62: Hepatocytes - Metabolism" 7 "Nucleoplasm, Nucleoli fibrillar center, Microtubules" "Cytokinetic bridge" "HPA053785: AB_2682260, HPA077297: " "unprognostic (7.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-1)" "unprognostic (1.28e-2)" "unprognostic (3.08e-1)" "unprognostic (7.24e-2)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.98e-1)" "unprognostic (3.52e-2)" "unprognostic (2.50e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.34e-7)" "unprognostic (3.43e-3)" "unprognostic (3.19e-2)" "unprognostic (2.38e-2)" "unprognostic (7.20e-2)" ETFB ENSG00000105379 "Electron transfer flavoprotein subunit beta" P38117 19 51345169-51366388 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 481.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 1214.9;Proximal enterocytes: 714.3;Proximal tubular cells: 972.0" "Cancer enhanced" "Detected in all" "liver cancer: 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018910, HPA018921, HPA018923" Supported Enhanced Mitochondria NA NA 170000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 2 Mitochondria "HPA018910: AB_1848280, HPA018921: AB_1848281, HPA018923: AB_1848282" "unprognostic (1.44e-1)" "prognostic favorable (6.45e-4)" "unprognostic (8.66e-2)" "unprognostic (3.08e-1)" "unprognostic (1.77e-1)" "unprognostic (3.94e-2)" "unprognostic (3.20e-1)" "unprognostic (6.93e-3)" "unprognostic (2.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.23e-1)" "unprognostic (4.75e-1)" "prognostic favorable (6.45e-5)" "unprognostic (2.19e-1)" "unprognostic (2.54e-1)" "unprognostic (4.83e-1)" "unprognostic (1.99e-1)" ETHE1 "HSCO, YF13H12" ENSG00000105755 "ETHE1 persulfide dioxygenase" O95571 19 43506719-43527230 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 247.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1734.4;Paneth cells: 661.4;Proximal enterocytes: 390.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028360, HPA029028, HPA029029" Enhanced Enhanced Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 45: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 3 Mitochondria "HPA028360: AB_10599297, HPA029028: AB_10602092, HPA029029: AB_10601998" "unprognostic (8.04e-2)" "unprognostic (3.33e-1)" "unprognostic (1.50e-2)" "unprognostic (2.45e-1)" "unprognostic (8.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.58e-1)" "prognostic unfavorable (9.58e-4)" "unprognostic (7.75e-2)" "unprognostic (2.28e-1)" "unprognostic (5.47e-2)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (5.27e-2)" "unprognostic (1.75e-1)" "unprognostic (9.72e-3)" "unprognostic (2.73e-2)" ETV7 "TEL-2, TEL2" ENSG00000010030 "ETS variant transcription factor 7" Q9Y603 6 36354091-36387800 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.5;skin 1: 15.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.1;Exocrine glandular cells: 18.6;Proximal enterocytes: 22.6;Spermatogonia: 26.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 18.9;T-reg: 16.4" "Group enriched" "Detected in many" 4 "granulocytes: 18.9;monocytes: 5.7;T-cells: 16.4" "Low cancer specificity" "Detected in many" "Breast - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in all" HPA029033 Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 Nucleoplasm "HPA029033: AB_10601375" "unprognostic (1.67e-2)" "prognostic favorable (5.16e-4)" "unprognostic (9.48e-2)" "unprognostic (1.57e-2)" "unprognostic (1.51e-1)" "unprognostic (2.62e-3)" "unprognostic (9.08e-2)" "unprognostic (4.11e-2)" "unprognostic (2.08e-2)" "prognostic favorable (5.32e-4)" "unprognostic (6.81e-3)" "unprognostic (1.11e-1)" "unprognostic (1.69e-3)" "unprognostic (5.54e-2)" "unprognostic (4.93e-1)" "unprognostic (1.27e-2)" "prognostic favorable (2.95e-6)" F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 57.4;stomach 1: 42.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 74.3;Distal enterocytes: 85.0;Gastric mucus-secreting cells: 74.3;Glandular and luminal cells: 66.8;Intestinal goblet cells: 51.9;Proximal enterocytes: 56.1;Suprabasal keratinocytes: 97.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 18.1" "Immune cell enhanced" "Detected in many" "neutrophil: 42.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.2" "Cancer enhanced" "Detected in many" "Bile duct cancer: 184.1" "Colon - Colon enterocytes, Heart muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Glandular & Luminal cells - Unknown function" 7 "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" FAAH FAAH-1 ENSG00000117480 "Fatty acid amide hydrolase" O00519 1 46394317-46413848 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 119.2;Proximal enterocytes: 83.9;Spermatocytes: 78.6" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 29.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "prostate cancer: 32.7" "Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007425 Approved Approved Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 30: White matter - Myelination" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 1 Cytosol "HPA007425: AB_1078820" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.51e-2)" "prognostic favorable (1.51e-4)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (4.39e-3)" "unprognostic (9.86e-2)" "prognostic favorable (4.25e-5)" "prognostic favorable (3.63e-5)" "unprognostic (2.66e-1)" "unprognostic (9.97e-2)" "unprognostic (5.00e-3)" FAHD1 "C16orf36, DKFZP566J2046" ENSG00000180185 "Fumarylacetoacetate hydrolase domain containing 1" Q6P587 16 1826967-1840207 "Enzymes, Predicted intracellular proteins" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 71.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 110.9;Proximal tubular cells: 174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025530, HPA043226, HPA043534" Enhanced Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria Nucleoplasm "CAB025530: , HPA043226: AB_2678370, HPA043534: AB_2678535" "unprognostic (3.71e-1)" "unprognostic (1.25e-2)" "prognostic favorable (8.27e-4)" "unprognostic (1.99e-1)" "unprognostic (6.74e-2)" "unprognostic (1.01e-3)" "unprognostic (2.89e-2)" "unprognostic (4.32e-1)" "unprognostic (1.13e-1)" "unprognostic (5.36e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "prognostic favorable (2.80e-14)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (3.31e-2)" FAHD2A CGI-105 ENSG00000115042 "Fumarylacetoacetate hydrolase domain containing 2A" Q96GK7 2 95402708-95416616 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 112.0" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 68.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042145, HPA044987, CAB045971, CAB045972" Enhanced NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 83: Liver - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 3 "CAB045971: AB_11126570, CAB045972: AB_11140511, HPA042145: AB_2677873, HPA044987: AB_2679170" "unprognostic (6.52e-2)" "unprognostic (1.25e-3)" "unprognostic (9.36e-2)" "unprognostic (1.27e-2)" "unprognostic (7.77e-3)" "unprognostic (6.82e-2)" "unprognostic (2.80e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (4.58e-2)" "unprognostic (7.30e-2)" "unprognostic (3.24e-2)" "unprognostic (1.17e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-2)" "unprognostic (1.55e-2)" FAM102A "bA203J24.7, C9orf132, Eeig1, SYM-3A" ENSG00000167106 "Family with sequence similarity 102 member A" Q5T9C2 9 127940582-127980989 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036030 Approved Cytosol NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 Cytosol "HPA036030: AB_10670675" "unprognostic (3.27e-1)" "unprognostic (1.66e-3)" "unprognostic (1.06e-3)" "unprognostic (4.69e-3)" "unprognostic (2.32e-1)" "unprognostic (1.21e-2)" "unprognostic (8.50e-2)" "unprognostic (2.97e-1)" "unprognostic (8.36e-2)" "unprognostic (1.01e-2)" "unprognostic (9.28e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (8.28e-3)" "unprognostic (6.98e-2)" FAM234A "C16orf9, DKFZP761D0211, FLJ32603, ITFG3" ENSG00000167930 "Family with sequence similarity 234 member A" Q9H0X4 16 234521-272183 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 180.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011651, HPA071871" Uncertain Approved Nucleoplasm,Mitochondria NA NA 5300000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 54: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria Nucleoplasm "HPA011651: , HPA071871: AB_2732188" "unprognostic (1.00e-1)" "unprognostic (1.85e-2)" "unprognostic (3.49e-1)" "unprognostic (4.80e-2)" "unprognostic (5.51e-2)" "unprognostic (2.03e-1)" "unprognostic (1.54e-2)" "unprognostic (2.55e-1)" "unprognostic (1.93e-1)" "unprognostic (2.21e-2)" "unprognostic (7.52e-2)" "unprognostic (1.16e-1)" "unprognostic (3.28e-2)" "unprognostic (2.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.25e-1)" "unprognostic (3.68e-1)" FAM3A "2-19, DXS560S, XAP-7" ENSG00000071889 "FAM3 metabolism regulating signaling molecule A" P98173 X 154506159-154516242 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 113.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025016, HPA035268, HPA056991" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" "Secreted to blood" "No annotated function" Yes No 15000 "Cluster 41: Basophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 16: Intestinal goblet cells - Mucin production" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "CAB025016: , HPA035268: , HPA056991: AB_2683303" "unprognostic (1.60e-1)" "unprognostic (2.72e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (3.19e-2)" "unprognostic (4.73e-2)" "unprognostic (5.19e-2)" "unprognostic (2.54e-2)" "unprognostic (2.57e-2)" "unprognostic (2.53e-1)" "unprognostic (6.27e-2)" "unprognostic (3.42e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (2.74e-1)" "unprognostic (1.41e-1)" "unprognostic (4.04e-1)" "unprognostic (9.71e-2)" FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 138.6;pancreas: 206.1;salivary gland: 116.0;stomach 1: 111.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 311.2;Exocrine glandular cells: 293.7;Proximal enterocytes: 846.1;Serous glandular cells: 260.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Region enriched" "Detected in single" 9 "choroid plexus: 2.3" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cancer enhanced" "Detected in many" "breast cancer: 12.3;colorectal cancer: 8.6;lung cancer: 7.7" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells (progenitors), Liver - Cholangiocyte, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" Cytokine NA NA 2080000 250000 "Cluster 48: Stomach - Proteolysis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 3 Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" FAM3C "GS3876, ILEI" ENSG00000196937 "FAM3 metabolism regulating signaling molecule C" Q92520 7 121348878-121396364 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 303.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "memory B-cell: 22.6;naive B-cell: 20.1" "Lineage enriched" "Detected in many" 7 "B-cells: 22.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043376, HPA050548" Enhanced Enhanced "Golgi apparatus" "Secreted in other tissues" "Developmental protein" NA NA 48000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 45 "Golgi apparatus" "HPA043376: AB_2678452, HPA050548: AB_2681169" "unprognostic (9.44e-2)" "unprognostic (3.91e-1)" "unprognostic (1.75e-1)" "unprognostic (8.11e-3)" "unprognostic (1.26e-2)" "unprognostic (3.09e-3)" "unprognostic (3.38e-3)" "unprognostic (2.44e-1)" "unprognostic (2.95e-1)" "unprognostic (1.22e-2)" "unprognostic (2.15e-3)" "unprognostic (1.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.48e-1)" "unprognostic (9.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.06e-2)" FAM83F ENSG00000133477 "Family with sequence similarity 83 member F" Q8NEG4 22 39994954-40043534 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 19.7;testis: 39.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 45.2;Late spermatids: 64.9;Proximal enterocytes: 36.1;Suprabasal keratinocytes: 37.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA051207, HPA064657" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 21: Testis - Unknown function" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 1 Mitochondria Nucleoplasm "HPA051207: AB_2681388, HPA064657: AB_2685313" "unprognostic (2.78e-2)" "unprognostic (3.91e-2)" "prognostic favorable (1.73e-4)" "unprognostic (5.36e-2)" "unprognostic (1.48e-5)" "unprognostic (1.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (4.79e-1)" "unprognostic (2.48e-1)" "prognostic favorable (9.40e-4)" "unprognostic (3.25e-1)" "unprognostic (1.10e-7)" "unprognostic (2.93e-1)" "unprognostic (2.37e-1)" "unprognostic (2.98e-2)" "unprognostic (8.32e-2)" FAM98C FLJ44669 ENSG00000130244 "Family with sequence similarity 98 member C" Q17RN3 19 38403093-38409088 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 94.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040930, HPA041730" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 45: Eosinophils - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" 9 "Nucleoplasm, Nucleoli" Cytosol "HPA040930: AB_10795484, HPA041730: AB_10804114" "unprognostic (3.01e-2)" "unprognostic (6.44e-3)" "unprognostic (5.15e-2)" "unprognostic (1.94e-1)" "unprognostic (3.18e-1)" "unprognostic (8.10e-3)" "unprognostic (3.06e-1)" "unprognostic (2.15e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (8.51e-5)" "unprognostic (2.82e-2)" "unprognostic (8.91e-3)" "unprognostic (1.01e-1)" "unprognostic (2.37e-3)" "unprognostic (2.43e-1)" "unprognostic (2.96e-1)" "prognostic favorable (5.53e-4)" FBLIM1 "CAL, FBLP-1, migfilin" ENSG00000162458 "Filamin binding LIM protein 1" Q8WUP2 1 15756607-15786594 "Predicted intracellular proteins" "Cell adhesion, Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 168.5;Extravillous trophoblasts: 131.2;Gastric mucus-secreting cells: 126.2;Peritubular cells: 179.2;Proximal enterocytes: 133.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Lung - Smooth muscle cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025287, HPA072750" Approved Enhanced "Nucleoli fibrillar center,Cell Junctions,Focal adhesion sites" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Smooth muscle cells - Muscle contraction" 14 "Cell Junctions, Focal adhesion sites" "Nucleoli fibrillar center" "HPA025287: AB_1848443, HPA072750: AB_2686554" "unprognostic (4.10e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (2.26e-1)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.33e-2)" "unprognostic (8.77e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (2.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.33e-2)" "unprognostic (3.01e-1)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 298.7;kidney: 284.7;liver: 849.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 590.8;Macrophages: 270.0;Proximal enterocytes: 1060.4;Proximal tubular cells: 628.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 403.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "breast cancer: 70.7" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Macrophages, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005857, HPA012513, CAB033869" Enhanced Approved Mitochondria NA NA 21000000 "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" 6 Mitochondria "CAB033869: AB_1121520, HPA005857: AB_1848445, HPA012513: AB_1848446" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.40e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.13e-2)" "unprognostic (1.37e-1)" "prognostic favorable (1.79e-4)" "unprognostic (6.94e-3)" "unprognostic (4.52e-2)" "unprognostic (7.79e-2)" "unprognostic (7.59e-2)" "unprognostic (1.12e-1)" "prognostic favorable (6.86e-7)" "unprognostic (6.91e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.64e-5)" FBXL15 "Fbl15, FBXO37, MGC11279" ENSG00000107872 "F-box and leucine rich repeat protein 15" Q9H469 10 102419189-102423136 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Distal tubular cells: 159.8;Proximal enterocytes: 165.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" 2 "unprognostic (1.08e-1)" "unprognostic (3.96e-1)" "unprognostic (7.35e-2)" "unprognostic (1.19e-2)" "unprognostic (1.91e-1)" "unprognostic (8.39e-2)" "unprognostic (3.65e-2)" "unprognostic (1.70e-1)" "unprognostic (3.17e-2)" "unprognostic (2.33e-2)" "unprognostic (1.38e-3)" "unprognostic (1.72e-1)" "prognostic favorable (7.82e-4)" "unprognostic (3.99e-2)" "unprognostic (2.62e-1)" "unprognostic (9.97e-2)" "prognostic favorable (7.92e-4)" FBXL6 FBL6 ENSG00000182325 "F-box and leucine rich repeat protein 6" Q8N531 8 144355431-144359376 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 43.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008867 Approved Nucleoplasm,Vesicles Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 1 Nucleoplasm Vesicles "HPA008867: AB_2668161" "unprognostic (2.97e-2)" "unprognostic (3.30e-2)" "unprognostic (1.13e-3)" "unprognostic (3.13e-1)" "unprognostic (9.88e-2)" "unprognostic (1.68e-1)" "unprognostic (6.29e-3)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.43e-2)" "unprognostic (9.04e-2)" "unprognostic (9.73e-2)" "prognostic unfavorable (4.49e-10)" "unprognostic (3.93e-2)" "unprognostic (1.44e-1)" "unprognostic (3.53e-1)" "unprognostic (2.00e-1)" FBXW5 "DKFZP434B205, Fbw5, MGC20962" ENSG00000159069 "F-box and WD repeat domain containing 5" Q969U6 9 136940435-136944738 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 244.8" "Cell type enhanced" "Detected in all" "Early spermatids: 480.6;Late spermatids: 1839.1;Proximal enterocytes: 428.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046615 Approved Approved Mitochondria No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 36: Late spermatids - Unknown function" 21 Mitochondria "HPA046615: AB_10965648" "unprognostic (1.11e-1)" "unprognostic (1.10e-2)" "unprognostic (1.56e-2)" "prognostic favorable (1.02e-4)" "unprognostic (4.26e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-2)" "unprognostic (7.16e-3)" "unprognostic (2.64e-2)" "unprognostic (7.05e-2)" "unprognostic (3.51e-3)" "unprognostic (3.23e-2)" "prognostic favorable (4.74e-4)" "unprognostic (1.73e-2)" "unprognostic (3.64e-1)" "unprognostic (2.32e-1)" "unprognostic (2.13e-1)" FCGRT "FcgammaRn, FcRn" ENSG00000104870 "Fc gamma receptor and transporter" P55899 19 49506816-49526428 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1392.0;Paneth cells: 775.0;Proximal enterocytes: 1822.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 2360.0" "Group enriched" "Detected in all" 17 "dendritic cells: 924.4;granulocytes: 2360.0;monocytes: 1367.7" "Cancer enhanced" "Detected in all" "Bone cancer: 261.3" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012122, HPA015130" Enhanced NA NA 24000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Liver - Plasma proteins" "Cluster 8: Immune cells - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 58: Macrophages - Innate immune response" 5 "HPA012122: AB_1848474, HPA015130: AB_1848475" "unprognostic (2.19e-3)" "unprognostic (2.05e-2)" "unprognostic (1.89e-1)" "unprognostic (1.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.26e-1)" "unprognostic (8.58e-2)" "unprognostic (3.87e-3)" "unprognostic (2.81e-1)" "unprognostic (3.49e-2)" "unprognostic (2.00e-3)" "unprognostic (3.64e-1)" "unprognostic (3.67e-3)" "unprognostic (3.40e-1)" "unprognostic (1.40e-1)" "unprognostic (1.29e-2)" "unprognostic (2.18e-3)" FLVCR1 "AXPC1, FLVCR, MFSD7B, PCA, SLC49A1" ENSG00000162769 "FLVCR heme transporter 1" Q9Y5Y0 1 212858275-212899363 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Erythrocyte maturation, Transport" Receptor "Disease variant, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.8" "Cell type enhanced" "Detected in all" "Enteroendocrine cells: 48.3;Proximal enterocytes: 55.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046646 Approved Approved "Cell Junctions" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Small intestine - Absorption" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" "Cell Junctions" "HPA046646: AB_2679735" "unprognostic (2.09e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.01e-1)" "unprognostic (2.83e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (1.03e-1)" "unprognostic (1.21e-1)" "unprognostic (3.88e-2)" "prognostic favorable (3.50e-4)" "unprognostic (1.89e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (7.15e-2)" "unprognostic (2.25e-1)" "unprognostic (3.91e-2)" "unprognostic (7.29e-3)" FLVCR2 "C14orf58, CCT, FLJ20371, MFSD7C, SLC49A2" ENSG00000119686 "FLVCR heme transporter 2" Q9UPI3 14 75578620-75663214 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 29.3" "Cell type enhanced" "Detected in many" "Early spermatids: 73.3;Kupffer cells: 41.1;Late spermatids: 139.4;Microglial cells: 39.4;Proximal enterocytes: 41.4;Syncytiotrophoblasts: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 14.1;intermediate monocyte: 14.6;myeloid DC: 7.6;non-classical monocyte: 11.9" "Group enriched" "Detected in many" 7 "dendritic cells: 7.6;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037984 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA037984: AB_10672733" "unprognostic (2.42e-1)" "unprognostic (4.85e-2)" "unprognostic (4.19e-2)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "unprognostic (4.44e-2)" "unprognostic (8.72e-2)" "unprognostic (2.78e-1)" "unprognostic (3.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.22e-1)" "unprognostic (4.80e-2)" "prognostic favorable (2.53e-5)" "unprognostic (6.69e-2)" "unprognostic (9.94e-2)" "unprognostic (9.38e-2)" "unprognostic (1.16e-1)" FOXD1 "FKHL8, FREAC4" ENSG00000251493 "Forkhead box D1" Q16676 5 73444827-73448777 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.4;Microglial cells: 8.9;Muller glia cells: 17.3;Proximal enterocytes: 5.3;Smooth muscle cells: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "spinal cord: 12.7" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Smooth muscle cells - Muscle contraction" "unprognostic (7.06e-4)" "unprognostic (1.02e-3)" "unprognostic (3.00e-5)" "unprognostic (1.48e-4)" "unprognostic (1.09e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (1.11e-2)" "unprognostic (2.24e-2)" "unprognostic (2.26e-1)" "unprognostic (7.92e-2)" "unprognostic (2.06e-2)" "unprognostic (6.18e-2)" "unprognostic (2.61e-10)" "unprognostic (3.64e-2)" "unprognostic (2.75e-1)" "unprognostic (1.29e-2)" "prognostic unfavorable (9.65e-4)" FRK "GTK, PTK5, RAK" ENSG00000111816 "Fyn related Src family tyrosine kinase" P42685 6 115931149-116060891 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 100.5;Oligodendrocytes: 91.0;Proximal enterocytes: 47.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025217, HPA030479, HPA072590" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Oligodendrocytes - Unknown function" 5 Nucleoplasm Cytosol "CAB025217: , HPA030479: AB_2732457, HPA072590: " "unprognostic (7.70e-3)" "unprognostic (1.99e-2)" "unprognostic (1.11e-1)" "unprognostic (4.68e-3)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (4.23e-2)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (7.54e-2)" "prognostic favorable (9.66e-7)" "unprognostic (1.52e-2)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.10e-1)" FRMD1 "bA164L23.1, DKFZp434O0117, FLJ00181, FLJ22615, FLJ40260" ENSG00000153303 "FERM domain containing 1" Q8N878 6 168053095-168101511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.5;kidney: 4.5;lymphoid tissue: 10.0;stomach 1: 5.6;testis: 4.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 56.1;Late spermatids: 19.2;Paneth cells: 124.6;Proximal enterocytes: 20.1;Proximal tubular cells: 25.6" "Cancer enriched" "Detected in single" 6 "colorectal cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Skin - Adipocytes (Skin), Stomach - Parietal cells" "Low region specificity" "Detected in many" HPA030347 Enhanced Uncertain "Actin filaments" NA NA "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: Neuronal - Sensory perception" "Cluster 5: Enterocytes - Absorption" 1 "Actin filaments" "HPA030347: AB_10600207" "unprognostic (2.43e-2)" "unprognostic (2.74e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (2.58e-4)" "unprognostic (8.63e-2)" "unprognostic (2.62e-1)" "unprognostic (7.51e-2)" "unprognostic (9.12e-2)" "unprognostic (8.23e-2)" "unprognostic (1.71e-2)" "unprognostic (1.01e-1)" "unprognostic (9.11e-3)" FTH1 "FHC, FTH, FTHL6, PIG15, PLIF" ENSG00000167996 "Ferritin heavy chain 1" P02794 11 61959718-61967634 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Iron storage" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 53887.5;monocytes: 46189.2;Proximal enterocytes: 29978.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008623 Approved NA NA 5600000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 7: Non-specific - Ribosome" "Cluster 7: Liver cancer - Metabolism" "Cluster 14: Langerhans cells - Innate immune response" 8 "CAB008623: " "unprognostic (7.15e-2)" "unprognostic (1.52e-2)" "unprognostic (2.27e-1)" "unprognostic (2.00e-2)" "unprognostic (2.53e-1)" "prognostic unfavorable (7.56e-5)" "prognostic unfavorable (6.18e-4)" "unprognostic (3.08e-2)" "unprognostic (2.48e-2)" "unprognostic (6.65e-2)" "unprognostic (2.44e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (5.20e-5)" "unprognostic (2.99e-1)" "unprognostic (4.89e-2)" "unprognostic (3.44e-1)" "unprognostic (5.83e-2)" FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 182.1;Distal enterocytes: 193.9;Paneth cells: 181.1;Proximal enterocytes: 220.7;Syncytiotrophoblasts: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Lung - Macrophages, Pancreas - Macrophages, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" Enzyme NA NA 60000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" 3 Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" FUT2 "SE, Se2, SEC2, sej" ENSG00000176920 "Fucosyltransferase 2" Q10981 19 48695971-48705951 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.2;salivary gland: 64.3;stomach 1: 28.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 87.2;Gastric mucus-secreting cells: 69.0;Ionocytes: 145.1;Mucus glandular cells: 141.4;Proximal enterocytes: 187.9;Salivary duct cells: 110.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.9;Gastric cancer: 18.6" "Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Region enhanced" "Detected in some" "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA014402 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" 3 "Plasma membrane" Cytosol "HPA014402: AB_1849194" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (2.80e-3)" "unprognostic (4.63e-3)" "unprognostic (2.63e-1)" "prognostic favorable (5.83e-4)" "unprognostic (6.30e-3)" "unprognostic (6.55e-3)" "unprognostic (1.58e-1)" "unprognostic (8.44e-2)" "unprognostic (7.89e-2)" "unprognostic (5.11e-1)" "unprognostic (4.04e-2)" "unprognostic (6.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" FUT3 "CD174, LE" ENSG00000171124 "Fucosyltransferase 3 (Lewis blood group)" P21217 19 5842888-5851471 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 154.2;intestine: 70.3;retina: 79.6;salivary gland: 81.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 116.5;Ductal cells: 44.3;Enteroendocrine cells: 39.7;Intestinal goblet cells: 83.2;Ionocytes: 55.6;Paneth cells: 49.4;Proximal enterocytes: 79.6;Undifferentiated cells: 42.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 42.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" HPA046966 Supported NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "HPA046966: AB_2679879" "prognostic unfavorable (6.86e-4)" "unprognostic (2.59e-1)" "unprognostic (1.06e-1)" "unprognostic (9.12e-2)" "unprognostic (8.58e-3)" "unprognostic (1.63e-3)" "unprognostic (3.88e-2)" "unprognostic (2.03e-2)" "unprognostic (4.02e-2)" "unprognostic (3.98e-2)" "unprognostic (4.21e-2)" "unprognostic (2.99e-1)" "prognostic favorable (8.22e-7)" "unprognostic (5.66e-3)" "unprognostic (9.56e-2)" "unprognostic (4.30e-2)" "unprognostic (1.07e-1)" FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830408-5839722 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 77.2;kidney: 35.1;salivary gland: 44.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 49.2;Intestinal goblet cells: 72.0;Ionocytes: 40.1;Paneth cells: 32.8;Proximal enterocytes: 118.6;Proximal tubular cells: 57.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.8" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "colorectal cancer: 7.9;Gastric cancer: 4.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA 51000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "Golgi apparatus" "HPA043707: AB_2678628, HPA046966: AB_2679879" "unprognostic (3.65e-2)" "unprognostic (3.00e-3)" "unprognostic (2.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.12e-4)" "unprognostic (8.02e-2)" "unprognostic (6.68e-3)" "unprognostic (4.01e-2)" "unprognostic (8.53e-2)" "unprognostic (2.62e-2)" "unprognostic (4.94e-2)" "prognostic favorable (3.17e-8)" "unprognostic (1.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" GALK1 GALK ENSG00000108479 "Galactokinase 1" P51570 17 75751594-75765236 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Galactose metabolism" "Kinase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 123.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 119.4;Hepatocytes: 123.8;Proximal enterocytes: 139.1" "Cancer enhanced" "Detected in all" "liver cancer: 42.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007094, HPA016960" Approved Approved "Golgi apparatus,Cytosol" NA NA 57000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 83: Liver - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 1 Cytosol "Golgi apparatus" "HPA007094: AB_1078939, HPA016960: AB_1849430" "unprognostic (1.16e-1)" "unprognostic (1.33e-2)" "unprognostic (1.81e-2)" "unprognostic (2.94e-2)" "unprognostic (1.00e-1)" "unprognostic (2.21e-1)" "unprognostic (1.29e-1)" "unprognostic (7.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.04e-2)" "unprognostic (1.06e-1)" "unprognostic (2.35e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (3.04e-1)" "unprognostic (1.71e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.62e-5)" GALM ENSG00000143891 "Galactose mutarotase" Q96C23 2 38666081-38741237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 83.8;kidney: 115.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 112.5;Peritubular cells: 99.2;Proximal enterocytes: 171.3;Proximal tubular cells: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 68.5" "Group enriched" "Detected in all" 5 "granulocytes: 39.2;T-cells: 68.5" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035472, HPA035473, HPA064835" Enhanced Uncertain Nucleoplasm NA NA 620000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Nucleoplasm "HPA035472: AB_10669906, HPA035473: AB_2674642, HPA064835: AB_2732723" "unprognostic (5.02e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (9.20e-2)" "unprognostic (1.88e-2)" "unprognostic (9.99e-3)" "unprognostic (1.63e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (6.65e-2)" "unprognostic (6.45e-2)" "prognostic favorable (9.06e-5)" "unprognostic (1.70e-2)" "unprognostic (1.62e-1)" "unprognostic (4.34e-1)" "prognostic favorable (1.32e-4)" GALNT14 "FLJ12691, GalNac-T10, GalNac-T14" ENSG00000158089 "Polypeptide N-acetylgalactosaminyltransferase 14" Q96FL9 2 30910467-31155202 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 39.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 27.9;Inhibitory neurons: 75.8;Oocytes: 17.6;Proximal enterocytes: 19.2;Proximal tubular cells: 34.6" "Cancer enriched" "Detected in many" 7 "renal cancer: 45.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "neutrophil: 8.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.5" "Cancer enriched" "Detected in many" 5 "Kidney cancer: 123.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030138 Approved "Nucleoplasm,Golgi apparatus" NA NA 27000 "Cluster 20: Non-specific - DNA binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" Nucleoplasm "HPA030138: AB_2673332" "unprognostic (5.69e-2)" "unprognostic (1.35e-1)" "unprognostic (2.05e-2)" "unprognostic (2.82e-3)" "unprognostic (3.85e-2)" "unprognostic (2.10e-2)" "unprognostic (3.32e-1)" "unprognostic (7.58e-2)" "unprognostic (1.96e-1)" "unprognostic (2.80e-1)" "unprognostic (1.22e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (5.18e-3)" "unprognostic (2.67e-2)" "unprognostic (2.56e-1)" "unprognostic (9.51e-3)" GATA5 "bB379O24.1, GATAS" ENSG00000130700 "GATA binding protein 5" Q9BWX5 20 62463497-62475995 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.9;testis: 11.2;urinary bladder: 14.9" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 24.8;Mesothelial cells: 13.8;Proximal enterocytes: 37.3;Sertoli cells: 19.0" "Cancer enhanced" "Detected in many" "stomach cancer: 5.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.8" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA067583 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 22: Proximal enterocytes - Digestion" 7 Nucleoplasm Cytosol "HPA067583: AB_2685867" "unprognostic (2.21e-1)" "unprognostic (2.28e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-2)" "unprognostic (2.66e-1)" "unprognostic (2.39e-1)" "unprognostic (2.62e-1)" "unprognostic (8.34e-2)" "unprognostic (1.69e-2)" "unprognostic (5.70e-2)" "unprognostic (1.27e-2)" "unprognostic (7.96e-3)" "unprognostic (2.00e-2)" "unprognostic (1.04e-1)" "unprognostic (2.36e-2)" "unprognostic (5.39e-3)" GBA2 "AD035, DKFZp762K054, KIAA1605, SPG46" ENSG00000070610 "Glucosylceramidase beta 2" Q9HCG7 9 35736866-35749228 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 80.3;Rod photoreceptor cells: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024026 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Nucleoplasm, Golgi apparatus" Cytosol "HPA024026: AB_1849530" "unprognostic (3.34e-2)" "unprognostic (2.90e-1)" "unprognostic (2.99e-1)" "unprognostic (1.06e-2)" "unprognostic (1.41e-1)" "unprognostic (5.83e-3)" "unprognostic (2.20e-2)" "unprognostic (2.09e-2)" "unprognostic (3.99e-2)" "unprognostic (8.69e-2)" "prognostic favorable (6.00e-4)" "unprognostic (9.01e-3)" "prognostic favorable (1.24e-11)" "unprognostic (7.62e-3)" "unprognostic (2.94e-1)" "unprognostic (7.69e-2)" "prognostic favorable (6.60e-4)" GBP3 FLJ10961 ENSG00000117226 "Guanylate binding protein 3" Q9H0R5 1 89006679-89022894 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 92.5;Ductal cells: 56.1;Proximal enterocytes: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA045657 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Non-specific - Mixed function" 4 "HPA045657: AB_10961631" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (6.30e-2)" "unprognostic (1.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.02e-1)" "unprognostic (2.18e-1)" "unprognostic (4.39e-2)" "unprognostic (3.47e-1)" "unprognostic (7.44e-2)" "unprognostic (4.42e-2)" "unprognostic (1.98e-1)" "unprognostic (1.86e-2)" "unprognostic (1.66e-2)" "unprognostic (9.70e-3)" "unprognostic (3.06e-2)" "unprognostic (5.06e-3)" GCNT3 "C2/4GnT, C2GnT-M, C2GnT2" ENSG00000140297 "Glucosaminyl (N-acetyl) transferase 3, mucin type" O95395 15 59594875-59640239 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 73.0;intestine: 138.1;salivary gland: 54.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 105.0;Distal enterocytes: 215.7;Ductal cells: 97.2;Glandular and luminal cells: 76.4;Oocytes: 61.0;Proximal enterocytes: 86.0" "Group enriched" "Detected in many" 4 "colorectal cancer: 16.4;pancreatic cancer: 29.8;stomach cancer: 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 52.0;pancreatic cancer: 51.3" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA011154 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Golgi apparatus" Vesicles "HPA011154: AB_1078961" "unprognostic (5.09e-2)" "unprognostic (2.39e-1)" "unprognostic (5.92e-2)" "prognostic favorable (1.78e-4)" "unprognostic (3.99e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (6.49e-5)" "unprognostic (1.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.34e-1)" "unprognostic (1.64e-2)" "unprognostic (1.63e-1)" "unprognostic (4.02e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-2)" "unprognostic (4.65e-2)" "unprognostic (2.43e-1)" GCNT4 "C2GNT3, LINC01336" ENSG00000176928 "Glucosaminyl (N-acetyl) transferase 4" Q9P109 5 75025346-75052558 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.4;lymphoid tissue: 15.0;stomach 1: 18.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.5;Cytotrophoblasts: 37.1;Gastric mucus-secreting cells: 16.5;granulocytes: 17.1;Pancreatic endocrine cells: 17.0;Proximal enterocytes: 24.9;Syncytiotrophoblasts: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 22.5" "Group enriched" "Detected in many" 54 "granulocytes: 22.5;T-cells: 18.2" "Cancer enhanced" "Detected in many" "Rhabdoid: 8.7;testis cancer: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037431 Approved Supported "Nucleoplasm,Golgi apparatus" No NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Small intestine - Absorption" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus" Nucleoplasm "HPA037431: AB_10670382" "unprognostic (1.88e-2)" "unprognostic (5.63e-2)" "unprognostic (6.05e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-1)" "unprognostic (4.98e-2)" "unprognostic (4.11e-3)" "unprognostic (1.63e-2)" "unprognostic (3.47e-1)" "unprognostic (2.20e-2)" "unprognostic (4.49e-3)" "unprognostic (6.04e-2)" "prognostic favorable (1.93e-7)" "unprognostic (8.39e-2)" "unprognostic (1.93e-1)" "unprognostic (6.06e-2)" "unprognostic (5.82e-2)" GFER "ALR, ERV1, HERV1, HPO1, HPO2, HSS" ENSG00000127554 "Growth factor, augmenter of liver regeneration" P55789 16 1984193-1987749 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Oxidoreductase" "Cataract, Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 170.5;Late spermatids: 156.0;Proximal enterocytes: 393.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041227, HPA063553" Approved Enhanced Mitochondria,Cytosol "Secreted to blood" "Growth factor" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 5 Cytosol Mitochondria "HPA041227: AB_10795538, HPA063553: AB_2685038" "unprognostic (5.35e-2)" "unprognostic (2.11e-2)" "unprognostic (3.08e-1)" "unprognostic (4.42e-2)" "unprognostic (3.15e-1)" "unprognostic (2.63e-1)" "unprognostic (1.27e-2)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.56e-1)" "unprognostic (5.93e-2)" "prognostic favorable (4.06e-4)" "unprognostic (4.93e-2)" "unprognostic (3.64e-1)" "unprognostic (3.56e-1)" "unprognostic (1.09e-2)" GGT6 FLJ90165 ENSG00000167741 "Gamma-glutamyltransferase 6" Q6P531 17 4556927-4560818 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 52.3;intestine: 51.6;salivary gland: 54.2;skin 1: 54.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 215.6;Intestinal goblet cells: 65.0;Paneth cells: 114.7;Proximal enterocytes: 128.6;Suprabasal keratinocytes: 65.1;Undifferentiated cells: 63.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 14.1;colorectal cancer: 19.1;Gallbladder cancer: 13.9" "Colon - Colon enterocytes, Liver - Cholangiocyte" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023362, HPA027213" Approved NA NA 72000 "Cluster 48: Stomach - Proteolysis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 6 "HPA023362: AB_1848955, HPA027213: AB_10601326" "unprognostic (2.23e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-3)" "unprognostic (4.51e-2)" "unprognostic (9.71e-2)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "prognostic favorable (4.35e-4)" "unprognostic (2.10e-1)" "unprognostic (2.33e-1)" "unprognostic (3.07e-2)" "unprognostic (5.06e-2)" "prognostic favorable (9.42e-7)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (9.17e-2)" "unprognostic (8.07e-3)" GIPC2 "FLJ20075, SEMCAP-2" ENSG00000137960 "GIPC PDZ domain containing family member 2" Q8TF65 1 77979542-78138444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.9;kidney: 39.9;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 117.4;Proximal tubular cells: 273.5;Undifferentiated cells: 58.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bile duct cancer: 6.6;colorectal cancer: 8.4;Gastric cancer: 6.4;liver cancer: 4.0;pancreatic cancer: 2.5" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA051212, HPA062684" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 6 Nucleoplasm Cytosol "HPA051212: , HPA062684: AB_2684833" "unprognostic (1.72e-2)" "unprognostic (9.37e-2)" "prognostic favorable (5.49e-4)" "unprognostic (1.09e-2)" "unprognostic (1.43e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" "unprognostic (2.35e-1)" "unprognostic (7.63e-2)" "unprognostic (2.22e-1)" "unprognostic (5.91e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.11e-6)" "unprognostic (6.55e-2)" "unprognostic (1.78e-1)" "unprognostic (4.18e-2)" "unprognostic (1.29e-1)" GK "GK1, GKD" ENSG00000198814 "Glycerol kinase" P32189 X 30653359-30731462 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 85.0;kidney: 101.6;liver: 69.4" "Cell type enhanced" "Detected in many" "Langerhans cells: 167.7;Macrophages: 115.5;monocytes: 392.2;Proximal enterocytes: 138.9;Proximal tubular cells: 131.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "neutrophil: 160.1" "Lineage enriched" "Detected in all" 8 "granulocytes: 160.1" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA060687 Supported NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA060687: AB_2684343" "unprognostic (8.78e-3)" "unprognostic (8.41e-3)" "unprognostic (1.28e-2)" "unprognostic (3.77e-2)" "unprognostic (3.15e-1)" "unprognostic (4.15e-3)" "unprognostic (5.52e-2)" "unprognostic (1.42e-2)" "unprognostic (3.85e-1)" "unprognostic (8.56e-3)" "unprognostic (1.30e-2)" "unprognostic (1.58e-2)" "prognostic favorable (3.24e-9)" "unprognostic (1.59e-1)" "unprognostic (9.35e-2)" "unprognostic (4.57e-3)" "unprognostic (4.11e-3)" GLRX "GRX, GRX1" ENSG00000173221 Glutaredoxin P35754 5 95751319-95822726 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 749.7" "Cell type enhanced" "Detected in many" "Distal tubular cells: 620.8;Extravillous trophoblasts: 899.4;Oocytes: 773.5;Proximal enterocytes: 995.4;Proximal tubular cells: 977.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008634, HPA046431, CAB069419" Approved Supported "Plasma membrane,Cytosol" NA NA 6300000 "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 1 "Plasma membrane, Cytosol" "CAB008634: AB_1616672, CAB069419: AB_1616670, HPA046431: AB_2679663" "unprognostic (1.69e-1)" "unprognostic (1.32e-1)" "unprognostic (1.94e-2)" "unprognostic (4.81e-2)" "unprognostic (2.01e-2)" "unprognostic (2.22e-2)" "unprognostic (8.62e-3)" "unprognostic (9.31e-3)" "unprognostic (1.99e-2)" "unprognostic (1.65e-2)" "unprognostic (2.34e-1)" "unprognostic (1.82e-1)" "unprognostic (8.11e-2)" "unprognostic (2.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" "unprognostic (2.61e-1)" GMDS "GMD, SDR3E1" ENSG00000112699 "GDP-mannose 4,6-dehydratase" O60547 6 1623806-2245605 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 103.0;salivary gland: 102.5;stomach 1: 94.6" "Cell type enhanced" "Detected in all" "Excitatory neurons: 201.6;Gastric mucus-secreting cells: 270.6;Intestinal goblet cells: 296.1;Proximal enterocytes: 202.4;Serous glandular cells: 200.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031528 Enhanced NA NA 72000 "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "HPA031528: AB_10601016" "unprognostic (5.94e-2)" "unprognostic (3.92e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.89e-4)" "unprognostic (4.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.10e-3)" "unprognostic (7.15e-2)" "unprognostic (2.29e-1)" "unprognostic (8.02e-2)" "unprognostic (2.38e-1)" "unprognostic (4.41e-1)" "prognostic favorable (5.93e-4)" "unprognostic (2.45e-1)" "unprognostic (2.84e-1)" "unprognostic (6.68e-2)" "unprognostic (1.12e-1)" GNA11 "FBH, FBH2, FHH2, HHC2" ENSG00000088256 "G protein subunit alpha 11" P29992 19 3094362-3123999 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 208.1;Proximal enterocytes: 300.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048886 Approved NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" "HPA048886: AB_2680544" "unprognostic (4.64e-3)" "unprognostic (2.21e-1)" "unprognostic (3.12e-1)" "unprognostic (2.23e-2)" "unprognostic (1.30e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (4.86e-4)" "unprognostic (2.56e-2)" "unprognostic (1.40e-1)" "unprognostic (6.26e-2)" "unprognostic (7.85e-3)" "unprognostic (2.43e-1)" "prognostic favorable (1.48e-11)" "unprognostic (1.05e-2)" "unprognostic (1.01e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-1)" GNG12 ENSG00000172380 "G protein subunit gamma 12" Q9UBI6 1 67701475-67833467 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057790, HPA062208" Enhanced Supported Approved Mitochondria NA NA 550000 "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 32: Smooth muscle cells - Muscle contraction" 1 Mitochondria "HPA057790: AB_2683527, HPA062208: AB_2684711" "unprognostic (5.18e-2)" "unprognostic (1.76e-3)" "unprognostic (4.46e-3)" "unprognostic (7.77e-2)" "unprognostic (1.06e-1)" "unprognostic (4.71e-2)" "unprognostic (5.29e-2)" "unprognostic (5.84e-3)" "unprognostic (5.50e-2)" "unprognostic (3.41e-2)" "unprognostic (4.46e-3)" "unprognostic (8.13e-2)" "unprognostic (4.12e-3)" "unprognostic (2.33e-2)" "unprognostic (9.33e-2)" "unprognostic (7.78e-2)" "unprognostic (2.14e-3)" GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 106.8;parathyroid gland: 209.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 183.5;Paneth cells: 131.8;Proximal enterocytes: 348.1;Proximal tubular cells: 138.5;Undifferentiated cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 2 "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" GPR35 ENSG00000178623 "G protein-coupled receptor 35" Q9HC97 2 240605430-240633159 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 45.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 74.8;Intestinal goblet cells: 27.5;Langerhans cells: 42.6;monocytes: 55.1;Paneth cells: 31.5;Proximal enterocytes: 90.4" "Group enriched" "Detected in many" 4 "colorectal cancer: 20.7;pancreatic cancer: 6.9;stomach cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "classical monocyte: 31.0;eosinophil: 32.6;intermediate monocyte: 44.7;myeloid DC: 27.6;non-classical monocyte: 12.3" "Group enriched" "Detected in many" 16 "dendritic cells: 27.6;granulocytes: 32.6;monocytes: 44.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 32.8;colorectal cancer: 59.8;Gastric cancer: 38.3" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "unprognostic (1.05e-1)" "unprognostic (2.89e-2)" "unprognostic (4.35e-2)" "unprognostic (1.53e-1)" "unprognostic (5.99e-2)" "unprognostic (3.94e-3)" "unprognostic (2.71e-2)" "prognostic unfavorable (5.86e-4)" "unprognostic (2.01e-1)" "unprognostic (2.07e-1)" "unprognostic (7.98e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (2.59e-5)" "unprognostic (7.03e-3)" "unprognostic (1.30e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-3)" GPRIN2 "KIAA0514, MGC15171" ENSG00000204175 "G protein regulated inducer of neurite outgrowth 2" O60269 10 46541736-46556658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.2;skin 1: 16.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.7;Distal enterocytes: 17.6;Intestinal goblet cells: 47.8;Late spermatids: 20.3;Proximal enterocytes: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 6.0;prostate cancer: 8.1" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "HPA038129, HPA070760" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 16: Intestinal goblet cells - Mucin production" 3 "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA038129: AB_2675846, HPA070760: " "unprognostic (1.00e-2)" "unprognostic (1.91e-1)" "unprognostic (1.77e-2)" "prognostic unfavorable (8.60e-8)" "unprognostic (5.77e-2)" "prognostic favorable (3.47e-4)" "unprognostic (2.23e-1)" "unprognostic (2.67e-2)" "unprognostic (2.54e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "unprognostic (1.98e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.67e-3)" GPT "ALT, ALT1, GPT1, SGPT" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 175.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.3;Hepatocytes: 191.0;Paneth cells: 63.6;Proximal enterocytes: 135.0;Proximal tubular cells: 151.6" "Cancer enriched" "Detected in many" 7 "liver cancer: 38.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced NA NA 17000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "CAB032997: AB_2261949, CAB032999: AB_2095427, HPA031059: AB_10600214, HPA031060: AB_10602178" "unprognostic (8.22e-3)" "unprognostic (2.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-5)" "unprognostic (9.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.41e-1)" "unprognostic (9.22e-2)" "prognostic favorable (2.19e-4)" "unprognostic (2.83e-2)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" GRTP1 "FLJ22474, TBC1D6" ENSG00000139835 "Growth hormone regulated TBC protein 1" Q5TC63 13 113324163-113364148 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 81.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 69.7;Distal enterocytes: 61.1;Proximal enterocytes: 67.0;Rod photoreceptor cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046201 Enhanced NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "HPA046201: AB_2679584" "unprognostic (5.31e-2)" "unprognostic (2.27e-3)" "unprognostic (1.94e-1)" "unprognostic (1.89e-1)" "unprognostic (4.42e-2)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (6.05e-2)" "unprognostic (1.30e-2)" "unprognostic (3.07e-3)" "prognostic favorable (1.50e-5)" "unprognostic (4.41e-3)" "unprognostic (5.55e-2)" "unprognostic (8.56e-2)" "unprognostic (4.50e-3)" GSDMB "GSDML, PRO2521" ENSG00000073605 "Gasdermin B" Q8TAX9 17 39904595-39919854 "Predicted intracellular proteins, Transporters" "Cytolysis, Necrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.1;liver: 51.6;stomach 1: 46.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.3;Gastric mucus-secreting cells: 60.1;Intestinal goblet cells: 43.6;Paneth cells: 39.4;Proximal enterocytes: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "CAB013681, HPA023925, HPA052407" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm Cytosol "CAB013681: , HPA023925: AB_1850383, HPA052407: AB_2681819" "unprognostic (5.78e-2)" "prognostic favorable (3.41e-5)" "unprognostic (1.27e-1)" "unprognostic (5.70e-2)" "unprognostic (6.85e-2)" "unprognostic (2.81e-1)" "unprognostic (1.10e-1)" "unprognostic (6.44e-2)" "unprognostic (3.81e-1)" "unprognostic (8.72e-2)" "unprognostic (2.34e-2)" "unprognostic (1.71e-2)" "prognostic unfavorable (5.13e-11)" "unprognostic (1.88e-1)" "unprognostic (1.99e-1)" "unprognostic (8.91e-2)" "prognostic favorable (5.91e-9)" GSDMD "DF5L, FLJ12150, GSDMDC1" ENSG00000104518 "Gasdermin D" P57764 8 143553207-143563062 "Predicted intracellular proteins, Transporters" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 181.0;Proximal enterocytes: 283.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004656, HPA044487" Uncertain Supported Nucleoplasm "Intracellular and membrane" Immunity NA NA 11000 "Cluster 33: Non-specific - ATP binding" "Cluster 47: Spleen - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 7 Nucleoplasm "CAB004656: AB_426076, HPA044487: AB_2678957" "unprognostic (1.11e-2)" "unprognostic (8.44e-2)" "unprognostic (6.72e-2)" "unprognostic (4.00e-2)" "unprognostic (4.38e-2)" "unprognostic (1.10e-1)" "unprognostic (1.66e-1)" "unprognostic (2.65e-1)" "unprognostic (7.20e-2)" "unprognostic (6.36e-2)" "unprognostic (4.66e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (1.43e-4)" "unprognostic (8.51e-3)" "unprognostic (1.60e-1)" "unprognostic (1.96e-1)" "unprognostic (6.77e-3)" GSTK1 GST13 ENSG00000197448 "Glutathione S-transferase kappa 1" Q9Y2Q3 7 143244093-143270854 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1141.9;Proximal enterocytes: 668.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006311, HPA022904" Supported Supported Peroxisomes NA NA 110000 "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 36: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 11: Late spermatids - Unknown function" 2 Peroxisomes "HPA006311: AB_1849786, HPA022904: AB_1849787" "prognostic favorable (4.41e-6)" "unprognostic (2.40e-1)" "unprognostic (6.53e-2)" "unprognostic (4.49e-3)" "unprognostic (2.92e-2)" "unprognostic (1.15e-2)" "unprognostic (1.37e-1)" "unprognostic (2.99e-1)" "unprognostic (1.43e-1)" "unprognostic (3.76e-3)" "unprognostic (1.99e-2)" "unprognostic (7.27e-2)" "prognostic favorable (2.10e-6)" "unprognostic (2.66e-2)" "unprognostic (2.94e-1)" "unprognostic (9.13e-2)" "unprognostic (2.15e-2)" GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109665496 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 132.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 406.9;Proximal tubular cells: 106.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 343.9" "Lineage enriched" "Detected in all" 9 "granulocytes: 343.9" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048652, HPA055972, HPA055973" Approved Approved "Cytokinetic bridge,Cytosol" Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" 3 Cytosol "Cytokinetic bridge" "HPA048652: AB_2680478, HPA055972: AB_2682992, HPA055973: AB_2682993" "prognostic favorable (9.96e-5)" "unprognostic (1.96e-3)" "unprognostic (7.49e-2)" "unprognostic (9.92e-3)" "unprognostic (1.48e-1)" "unprognostic (1.08e-2)" "unprognostic (8.47e-2)" "unprognostic (3.48e-2)" "unprognostic (1.20e-1)" "unprognostic (4.76e-2)" "unprognostic (3.73e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-1)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" GUCD1 "C22orf13, LLN4, MGC1842" ENSG00000138867 "Guanylyl cyclase domain containing 1" Q96NT3 22 24540423-24555935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 162.7;Proximal enterocytes: 147.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022786 Approved Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 43: Hepatocytes - Metabolism" 6 Nucleoplasm "HPA022786: AB_1845711" "unprognostic (1.58e-1)" "prognostic favorable (6.84e-4)" "unprognostic (2.83e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.51e-2)" "unprognostic (1.61e-1)" "unprognostic (3.96e-2)" "unprognostic (1.89e-1)" "prognostic favorable (7.26e-4)" "unprognostic (1.28e-1)" "unprognostic (3.55e-2)" "unprognostic (1.76e-2)" "unprognostic (4.36e-2)" "unprognostic (8.63e-2)" "unprognostic (1.59e-1)" "unprognostic (3.01e-2)" H2AC8 "H2A.1, H2A/a, H2AFA, HIST1H2AE" ENSG00000277075 "H2A clustered histone 8" P04908 6 26216921-26217437 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 38.4" "Cell type enhanced" "Detected in many" "Plasma cells: 35.9;Prostatic glandular cells: 33.7;Proximal enterocytes: 23.9" "Cancer enhanced" "Detected in all" "prostate cancer: 40.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "CAB012242, HPA041189" Supported Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 57: Platelets - Hemostasis" 27 Nucleoplasm "CAB012242: AB_470265, HPA041189: AB_2677357" "unprognostic (4.26e-2)" "unprognostic (1.55e-2)" "unprognostic (4.66e-2)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (1.50e-1)" "unprognostic (2.48e-2)" "unprognostic (7.22e-2)" "unprognostic (1.24e-2)" "unprognostic (6.99e-2)" "unprognostic (1.21e-3)" "unprognostic (1.30e-2)" "unprognostic (7.64e-2)" "unprognostic (1.15e-1)" "unprognostic (2.41e-1)" "unprognostic (2.20e-1)" "unprognostic (9.36e-2)" H2BC15 "H2B/d, H2BFD, HIST1H2BN" ENSG00000233822 "H2B clustered histone 15" Q99877 6 27838545-27855709 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Plasma cells: 34.2;Proximal enterocytes: 36.6;Rod photoreceptor cells: 29.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 61: Plasma cells - Immunoglobulins & histones" Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (2.29e-1)" "unprognostic (2.82e-2)" "unprognostic (1.33e-1)" "unprognostic (3.25e-2)" "unprognostic (3.22e-2)" "unprognostic (6.66e-2)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-1)" "unprognostic (4.41e-2)" "unprognostic (2.95e-3)" "unprognostic (2.05e-3)" "unprognostic (1.14e-4)" "unprognostic (9.62e-2)" "unprognostic (3.91e-1)" "unprognostic (9.62e-2)" "unprognostic (2.22e-2)" H2BC8 "H2B.1A, H2B/a, H2BFA, HIST1H2BG" ENSG00000273802 "H2B clustered histone 8" P62807 6 26216200-26216688 "Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 29.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 104.0;Plasma cells: 55.4;Prostatic glandular cells: 77.3;Proximal enterocytes: 62.7" "Cancer enhanced" "Detected in all" "prostate cancer: 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 5: Enterocytes - Absorption" 9 Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (1.40e-2)" "unprognostic (1.34e-2)" "unprognostic (4.55e-2)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (4.19e-2)" "unprognostic (1.63e-2)" "unprognostic (8.54e-2)" "unprognostic (6.69e-2)" "unprognostic (1.55e-1)" "unprognostic (2.36e-2)" "unprognostic (2.79e-2)" "prognostic unfavorable (1.70e-8)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.97e-2)" H2BC9 "H2B/j, H2BFJ, HIST1H2BH" ENSG00000275713 "H2B clustered histone 9" Q93079 6 26251614-26252075 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.0;lymphoid tissue: 11.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.0;Extravillous trophoblasts: 31.6;Paneth cells: 16.4;Plasma cells: 23.4;Proximal enterocytes: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 18.4;neutrophil: 14.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "HPA042205, HPA043013, HPA048671" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 67: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 61: Plasma cells - Immunoglobulins & histones" 2 Nucleoplasm Cytosol "HPA042205: AB_2677900, HPA043013: AB_2678269, HPA048671: AB_2680488" "unprognostic (5.83e-2)" "unprognostic (6.27e-3)" "unprognostic (4.50e-2)" "unprognostic (9.18e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.06e-3)" "unprognostic (3.08e-3)" "unprognostic (1.58e-2)" "unprognostic (2.75e-2)" "unprognostic (1.86e-1)" "unprognostic (3.22e-1)" "unprognostic (2.96e-8)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (2.40e-2)" "unprognostic (1.95e-3)" H3C6 "H3.1, H3/d, H3FD, HIST1H3E" ENSG00000274750 "H3 clustered histone 6" P68431 6 26224199-26227473 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 9.0;Distal enterocytes: 5.5;Prostatic glandular cells: 5.6;Proximal enterocytes: 5.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" "HPA042570, HPA050968, HPA064058" Approved Supported Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 5: Enterocytes - Absorption" 52 Nucleoplasm "HPA042570: AB_2678056, HPA050968: , HPA064058: " "unprognostic (2.42e-2)" "unprognostic (1.78e-1)" "unprognostic (1.78e-3)" "unprognostic (9.07e-2)" "unprognostic (1.34e-1)" "unprognostic (3.65e-1)" "unprognostic (1.23e-1)" "unprognostic (3.90e-1)" "unprognostic (1.83e-1)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (2.39e-2)" "unprognostic (1.76e-2)" "unprognostic (1.42e-1)" "unprognostic (4.88e-2)" "unprognostic (1.07e-1)" "unprognostic (7.66e-2)" H4C11 "H4/e, H4F2iv, H4FE, HIST1H4J" ENSG00000197238 "H4 clustered histone 11" P62805 6 27824092-27824480 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.5;Enteroendocrine cells: 20.9;Intestinal goblet cells: 9.9;Paneth cells: 15.7;Proximal enterocytes: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 6 "basophil: 81.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 81.5" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.3;lymphoma: 1.8" "Low region specificity" "Detected in some" HPA042201 Supported NA NA 25000000 "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" 54 "HPA042201: AB_2677898" "unprognostic (3.79e-2)" "unprognostic (2.05e-2)" "unprognostic (7.65e-2)" "unprognostic (8.35e-2)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" "unprognostic (2.99e-1)" "unprognostic (7.30e-2)" "unprognostic (3.77e-1)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "unprognostic (4.18e-2)" "unprognostic (1.79e-3)" "unprognostic (3.50e-1)" "unprognostic (2.77e-1)" "unprognostic (2.08e-1)" "unprognostic (4.24e-3)" H4C14 "H4/n, H4F2, H4FN, HIST2H4, HIST2H4A" ENSG00000270882 "H4 clustered histone 14" P62805 1 149832657-149839767 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.3;Gastric mucus-secreting cells: 1.2;Prostatic glandular cells: 5.3;Proximal enterocytes: 1.2;Proximal tubular cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA042201 Approved NA NA 25000000 "Cluster 24: Non-specific - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 40: Prostatic glandular cells - Transcription" 54 "HPA042201: AB_2677898" "unprognostic (1.90e-1)" "unprognostic (6.29e-2)" "unprognostic (1.50e-2)" "unprognostic (6.68e-2)" "unprognostic (3.65e-2)" "unprognostic (1.99e-2)" "unprognostic (6.99e-2)" "unprognostic (8.36e-2)" "unprognostic (4.66e-2)" "unprognostic (3.44e-1)" "unprognostic (4.91e-2)" "unprognostic (8.70e-2)" "unprognostic (6.78e-4)" "unprognostic (6.15e-2)" "unprognostic (3.63e-3)" "unprognostic (1.62e-2)" "unprognostic (5.99e-2)" H4C15 "H4/o, HIST2H4B" ENSG00000270276 "H4 clustered histone 15" P62805 1 149854045-149861159 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal enterocytes: 2.2;Gastric mucus-secreting cells: 3.5;Granulosa cells: 2.5;Plasma cells: 3.7;Proximal enterocytes: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA042201 Supported NA Yes 25000000 "Cluster 24: Non-specific - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 61: Plasma cells - Immunoglobulins & histones" 54 "HPA042201: AB_2677898" "unprognostic (8.20e-2)" "unprognostic (2.69e-1)" "unprognostic (1.77e-1)" H4C16 "H4-16, HIST4H4, MGC24116" ENSG00000197837 "H4 histone 16" P62805 12 14767999-14771131 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 32.4;Plasma cells: 13.5;Proximal enterocytes: 12.8;Rod photoreceptor cells: 23.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "CAB011503, CAB037279, HPA042201" Supported Supported Nucleoplasm NA NA 25000000 "Cluster 18: Non-specific - Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 61: Plasma cells - Immunoglobulins & histones" 54 Nucleoplasm "CAB011503: AB_873863, CAB037279: AB_1079064, HPA042201: AB_2677898" "unprognostic (1.87e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-2)" "unprognostic (6.89e-2)" "unprognostic (2.16e-2)" "unprognostic (4.86e-2)" "unprognostic (3.67e-2)" "unprognostic (9.69e-3)" "unprognostic (4.54e-2)" "unprognostic (3.25e-2)" "unprognostic (5.35e-2)" "unprognostic (6.62e-3)" "unprognostic (4.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.33e-3)" "unprognostic (2.01e-1)" "unprognostic (1.28e-3)" H4C5 "H4/j, H4FJ, HIST1H4E" ENSG00000276966 "H4 clustered histone 5" P62805 6 26204610-26205021 "Disease related genes, Predicted intracellular proteins" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells" HPA042201 Supported NA NA 25000000 "Cluster 24: Non-specific - Transcription" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 61: Plasma cells - Immunoglobulins & histones" 54 "HPA042201: AB_2677898" "unprognostic (8.62e-2)" "unprognostic (4.86e-2)" "unprognostic (5.71e-3)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.57e-1)" "unprognostic (5.08e-3)" "unprognostic (7.99e-2)" "unprognostic (1.21e-1)" "unprognostic (6.57e-2)" "unprognostic (2.34e-3)" "unprognostic (4.34e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (1.28e-2)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035241 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 288.6;Hepatocytes: 310.8;Proximal enterocytes: 386.9;Proximal tubular cells: 250.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "HPA039588: AB_10673425, HPA043888: AB_2678716" "unprognostic (1.73e-1)" "unprognostic (3.32e-3)" "unprognostic (3.05e-3)" "unprognostic (8.86e-3)" "unprognostic (1.83e-1)" "unprognostic (6.83e-2)" "unprognostic (9.26e-3)" "unprognostic (1.55e-2)" "unprognostic (9.22e-2)" "unprognostic (3.24e-2)" "unprognostic (2.96e-1)" "unprognostic (1.18e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.67e-1)" "unprognostic (4.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.88e-2)" HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 484.7" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 500.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 5: Enterocytes - Absorption" 8 Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" HDHD3 "C9orf158, MGC12904" ENSG00000119431 "Haloacid dehalogenase like hydrolase domain containing 3" Q9BSH5 9 113373419-113376986 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 151.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 217.9;Paneth cells: 152.2;Proximal enterocytes: 250.2;Proximal tubular cells: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020427, HPA024158, HPA024585" Enhanced Enhanced Nucleoli,Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 11 Nucleoli Vesicles "HPA020427: AB_1850561, HPA024158: AB_1850563, HPA024585: AB_1850565" "unprognostic (1.30e-1)" "prognostic favorable (2.72e-4)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (8.24e-3)" "unprognostic (1.57e-2)" "unprognostic (6.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (5.87e-2)" "prognostic favorable (3.54e-7)" "unprognostic (2.16e-2)" "unprognostic (1.84e-1)" "unprognostic (4.68e-1)" "unprognostic (1.19e-3)" HECTD3 FLJ21156 ENSG00000126107 "HECT domain E3 ubiquitin protein ligase 3" Q5T447 1 45002540-45011324 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.6;Proximal enterocytes: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027467 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 5: Enterocytes - Absorption" 1 "HPA027467: AB_10600710" "unprognostic (1.86e-1)" "unprognostic (1.19e-2)" "unprognostic (2.39e-1)" "unprognostic (1.58e-1)" "unprognostic (1.18e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.14e-5)" "unprognostic (1.74e-2)" "unprognostic (2.92e-2)" "unprognostic (7.42e-2)" "unprognostic (2.47e-1)" "unprognostic (8.39e-2)" "unprognostic (2.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.35e-1)" "prognostic favorable (1.85e-6)" "unprognostic (3.19e-1)" HEPH "CPL, KIAA0698" ENSG00000089472 Hephaestin Q9BQS7 X 66162671-66268867 "Metabolic proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.8;smooth muscle: 53.0" "Cell type enhanced" "Detected in many" "Astrocytes: 74.0;Distal enterocytes: 148.7;Enteroendocrine cells: 48.9;Intestinal goblet cells: 106.1;Paneth cells: 67.8;Proximal enterocytes: 123.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 37.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 19.2;testis cancer: 40.2" "Adipose visceral - Adipose progenitor cells, Colon - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005824 Approved NA NA 3700000 "Cluster 45: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA005824: AB_1850603" "unprognostic (3.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.25e-2)" "unprognostic (4.25e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (4.94e-2)" "unprognostic (6.17e-2)" "unprognostic (1.40e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (3.08e-2)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" HID1 "C17orf28, DMC1, HID-1" ENSG00000167861 "HID1 domain containing" Q8IV36 17 74950742-74973166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 150.8;pancreas: 108.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 66.0;Intestinal goblet cells: 92.8;Paneth cells: 96.4;Proximal enterocytes: 106.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.6" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "breast cancer: 86.5" "Breast - Breast glandular cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031406 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 9 "Golgi apparatus, Cytosol" "HPA031406: AB_2673866" "unprognostic (7.41e-2)" "unprognostic (1.96e-1)" "unprognostic (2.69e-1)" "unprognostic (2.22e-3)" "unprognostic (4.47e-3)" "unprognostic (6.79e-3)" "unprognostic (4.00e-2)" "unprognostic (1.11e-1)" "unprognostic (2.78e-1)" "unprognostic (3.90e-1)" "unprognostic (1.54e-3)" "unprognostic (1.37e-1)" "prognostic favorable (3.13e-5)" "unprognostic (1.17e-1)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.34e-4)" HKDC1 "FLJ22761, FLJ37767" ENSG00000156510 "Hexokinase domain containing 1" Q2TB90 10 69220332-69267552 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 52.0;retina: 45.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 32.4;Ductal cells: 33.0;Glandular and luminal cells: 47.0;Muller glia cells: 105.5;Proximal enterocytes: 51.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 5.8;naive CD8 T-cell: 2.3;T-reg: 5.4" "Lineage enriched" "Detected in single" 23 "T-cells: 5.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 68.7;Kidney cancer: 74.7" "Colon - Colon enterocytes" "Region enhanced" "Detected in many" "cerebral cortex: 11.9" "Low region specificity" "Detected in all" "HPA064198, HPA064230" Enhanced Enhanced Mitochondria No No "Cluster 11: T-cells - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Muller glia cells - Visual perception" Mitochondria "HPA064198: AB_2685210, HPA064230: AB_2685219" "unprognostic (1.29e-2)" "unprognostic (2.26e-2)" "unprognostic (1.86e-1)" "unprognostic (8.47e-2)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (6.31e-3)" "unprognostic (5.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (3.11e-1)" "unprognostic (1.04e-3)" "unprognostic (1.35e-1)" "unprognostic (2.24e-1)" "unprognostic (2.10e-3)" "unprognostic (2.19e-1)" HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29949572 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Ductal cells: 3710.2;Proximal enterocytes: 5253.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid - T-cells" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 4 "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" HLA-B AS ENSG00000234745 "Major histocompatibility complex, class I, B" P01889 6 31353872-31367067 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2389.7" "Cell type enhanced" "Detected in all" "monocytes: 4080.4;NK-cells: 5111.3;Proximal enterocytes: 4325.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Thyroid - T-cells" CAB015418 Enhanced NA NA 190000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 14: Langerhans cells - Innate immune response" 5 "CAB015418: AB_831547" "unprognostic (2.87e-2)" "unprognostic (1.49e-1)" "unprognostic (4.90e-2)" "unprognostic (2.65e-2)" "unprognostic (1.86e-1)" "unprognostic (1.81e-1)" "unprognostic (5.16e-3)" "unprognostic (8.51e-2)" "prognostic favorable (2.90e-4)" "unprognostic (2.69e-3)" "unprognostic (3.05e-2)" "unprognostic (1.59e-1)" "unprognostic (9.28e-3)" "unprognostic (3.27e-1)" "unprognostic (7.83e-2)" "unprognostic (8.24e-3)" "unprognostic (3.67e-2)" HLA-DMB "D6S221E, RING7" ENSG00000242574 "Major histocompatibility complex, class II, DM beta" P28068 6 32934629-32941028 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.6;lymphoid tissue: 99.1" "Cell type enhanced" "Detected in many" "B-cells: 242.4;dendritic cells: 307.0;Hofbauer cells: 312.7;Kupffer cells: 162.0;Langerhans cells: 576.8;Macrophages: 252.7;Proximal enterocytes: 278.8;Schwann cells: 142.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 129.1;dendritic cells: 85.5;monocytes: 73.9" "Cancer enhanced" "Detected in many" "lymphoma: 16.0;prostate cancer: 10.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Lung - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA012298, HPA077524" Supported Supported Vesicles NA NA "Cluster 47: Spleen - Immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" 1 Vesicles "HPA012298: AB_1853927, HPA077524: " "unprognostic (5.34e-2)" "unprognostic (1.63e-2)" "unprognostic (2.45e-2)" "prognostic favorable (3.89e-5)" "unprognostic (3.07e-1)" "unprognostic (7.64e-3)" "unprognostic (4.00e-1)" "unprognostic (3.46e-3)" "unprognostic (6.99e-2)" "unprognostic (8.76e-2)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (6.82e-3)" "unprognostic (2.03e-1)" "unprognostic (4.14e-2)" "unprognostic (8.35e-2)" "unprognostic (5.60e-2)" HLA-DRB5 ENSG00000198502 "Major histocompatibility complex, class II, DR beta 5" Q30154 6 32517353-32530287 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 344.6;lymphoid tissue: 413.0" "Cell type enhanced" "Detected in many" "B-cells: 669.7;Langerhans cells: 2064.3;Macrophages: 825.9;Proximal enterocytes: 707.4;Schwann cells: 1302.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 62.3" "Group enriched" "Detected in all" 10 "B-cells: 26.2;dendritic cells: 62.3;monocytes: 35.2" "Cancer enhanced" "Detected in many" "lymphoma: 116.2;skin cancer: 63.3" HPA043151 Supported NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA043151: AB_2678342" "unprognostic (1.97e-3)" "unprognostic (4.74e-2)" "unprognostic (3.30e-2)" "prognostic favorable (7.89e-4)" "unprognostic (2.28e-2)" "unprognostic (4.68e-3)" "unprognostic (9.09e-3)" "unprognostic (2.08e-3)" "unprognostic (1.06e-2)" "unprognostic (5.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.87e-1)" "unprognostic (2.89e-2)" "unprognostic (1.45e-1)" "unprognostic (7.60e-3)" "unprognostic (9.72e-2)" "unprognostic (5.48e-2)" HLA-F ENSG00000204642 "Major histocompatibility complex, class I, F" P30511 6 29722775-29738528 "Plasma proteins, Predicted membrane proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.8" "Cell type enhanced" "Detected in many" "monocytes: 256.5;NK-cells: 376.4;Proximal enterocytes: 320.9;T-cells: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" NA NA 15000000 "Cluster 47: Spleen - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 3 "unprognostic (3.07e-3)" "unprognostic (5.16e-2)" "unprognostic (3.05e-1)" "unprognostic (9.32e-2)" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (4.99e-2)" "unprognostic (2.68e-1)" "unprognostic (4.21e-3)" "unprognostic (2.43e-3)" "unprognostic (3.21e-2)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (1.26e-1)" "unprognostic (2.95e-2)" "unprognostic (4.13e-2)" "unprognostic (1.30e-2)" HMCN2 "DKFZp434P0216, FLJ23816" ENSG00000148357 "Hemicentin 2" Q8NDA2 9 130265760-130434123 "Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 32.8;intestine: 49.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 12.6;Early spermatids: 13.9;Fibroblasts: 17.9;Late spermatids: 12.8;Proximal enterocytes: 34.9;Skeletal myocytes: 21.5;Smooth muscle cells: 9.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 9.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.4;Sarcoma: 3.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053903, HPA070647" Enhanced Approved Vesicles "Secreted to extracellular matrix" Other NA NA 27000000 "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 53: Fibroblasts - ECM organization" Vesicles "HPA053903: AB_2682301, HPA070647: AB_2686290" "unprognostic (1.61e-1)" "unprognostic (8.05e-3)" "unprognostic (1.69e-1)" "unprognostic (5.53e-4)" "unprognostic (1.05e-1)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "unprognostic (8.78e-3)" "unprognostic (3.23e-1)" "unprognostic (3.97e-4)" "unprognostic (3.36e-2)" "unprognostic (3.93e-1)" "unprognostic (1.04e-3)" "unprognostic (1.53e-2)" "unprognostic (3.62e-2)" "unprognostic (8.96e-3)" "unprognostic (8.63e-2)" HOOK2 HK2 ENSG00000095066 "Hook microtubule tethering protein 2" Q96ED9 19 12763003-12872740 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 254.8;Proximal enterocytes: 269.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043519, HPA050351" Approved Supported Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 68: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" 11 "Vesicles, Cytosol" "HPA043519: AB_2678525, HPA050351: AB_2681102" "unprognostic (4.26e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-3)" "unprognostic (1.16e-1)" "unprognostic (4.57e-1)" "unprognostic (1.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.25e-3)" "unprognostic (3.06e-2)" "unprognostic (2.52e-2)" "unprognostic (1.75e-3)" "prognostic unfavorable (7.59e-5)" "prognostic favorable (3.28e-4)" "unprognostic (3.27e-3)" "unprognostic (5.74e-2)" "unprognostic (1.54e-1)" "unprognostic (2.91e-2)" HOXC11 HOX3H ENSG00000123388 "Homeobox C11" O43248 12 53973126-53977643 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.8;skin 1: 4.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.1;Langerhans cells: 1.4;Proximal enterocytes: 3.4;Spermatocytes: 3.4;Suprabasal keratinocytes: 2.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 15.8;breast cancer: 14.9" "Breast - Breast glandular cells (progenitors), Testis - Spermatocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 14 "spinal cord: 1.4" HPA038291 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Skin - Cornification" "Cluster 65: Non-specific - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 4 Nucleoplasm Cytosol "HPA038291: AB_10674552" "unprognostic (1.50e-3)" "unprognostic (1.93e-2)" "unprognostic (1.14e-2)" "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (1.17e-2)" "unprognostic (6.90e-3)" "unprognostic (1.32e-2)" "unprognostic (7.41e-3)" "unprognostic (4.46e-3)" "unprognostic (2.25e-1)" "unprognostic (3.26e-3)" "unprognostic (3.99e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" HOXD1 "HOX4, HOX4G" ENSG00000128645 "Homeobox D1" Q9GZZ0 2 176188668-176190907 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.5;epididymis: 7.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 19.1;Distal enterocytes: 27.8;Distal tubular cells: 21.5;Intestinal goblet cells: 21.6;Oligodendrocytes: 26.1;Oocytes: 19.1;Paneth cells: 19.4;Proximal enterocytes: 21.5;Undifferentiated cells: 27.2" "Cancer enriched" "Detected in many" 5 "ovarian cancer: 6.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.8" "Lung - Alveolar cells type 2" "Region enriched" "Detected in single" 5 "pons and medulla: 1.1" "Low region specificity" "Detected in many" "HPA040062, HPA056900" Enhanced Nucleoplasm NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm "HPA040062: AB_2676826, HPA056900: AB_2683270" "unprognostic (8.78e-2)" "unprognostic (9.97e-2)" "unprognostic (7.11e-3)" "unprognostic (1.06e-3)" "unprognostic (2.70e-1)" "unprognostic (3.19e-2)" "unprognostic (7.33e-2)" "unprognostic (4.10e-2)" "unprognostic (2.85e-1)" "unprognostic (2.44e-1)" "unprognostic (9.64e-2)" "unprognostic (4.02e-1)" "unprognostic (1.54e-5)" "unprognostic (4.33e-3)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.32e-1)" HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 229.1;urinary bladder: 363.3" "Cell type enhanced" "Detected in many" "Club cells: 296.3;Distal enterocytes: 340.0;Extravillous trophoblasts: 883.5;granulocytes: 945.1;Hepatocytes: 277.8;Proximal enterocytes: 470.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 52.4" "Region enhanced" "Detected in many" "choroid plexus: 17.4" "Group enriched" "Detected in many" 5 "basophil: 123.8;T-reg: 45.1" "Group enriched" "Detected in many" 73 "granulocytes: 123.8;T-cells: 45.1" "Cancer enhanced" "Detected in many" "testis cancer: 111.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 20000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 30: Granulocytes - Unknown function" Cytosol Nucleoplasm "HPA004919: AB_1079081, HPA005679: AB_1079080" "unprognostic (1.23e-3)" "unprognostic (1.61e-1)" "unprognostic (5.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.28e-2)" "unprognostic (3.54e-3)" "unprognostic (2.34e-2)" "prognostic favorable (3.20e-4)" "unprognostic (2.44e-1)" "unprognostic (2.59e-1)" "unprognostic (1.37e-4)" "unprognostic (2.33e-2)" HRCT1 "LGLL338, PRO537, UNQ338" ENSG00000196196 "Histidine rich carboxyl terminus 1" Q6UXD1 9 35906202-35907136 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 28.5;breast: 24.1" "Cell type enhanced" "Detected in many" "Adipocytes: 78.4;Distal enterocytes: 253.5;Intestinal goblet cells: 53.6;Paneth cells: 245.0;Proximal enterocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 23.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA067038 Approved Nucleoplasm NA NA "Cluster 45: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 5: Enterocytes - Absorption" Nucleoplasm "HPA067038: AB_2685767" "unprognostic (2.48e-2)" "unprognostic (4.88e-2)" "unprognostic (2.43e-2)" "unprognostic (2.49e-1)" "unprognostic (5.69e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.63e-2)" "unprognostic (2.53e-2)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.80e-1)" "unprognostic (1.18e-1)" "unprognostic (2.00e-1)" "unprognostic (9.41e-2)" "unprognostic (2.80e-1)" "unprognostic (9.43e-2)" HSD17B11 "17-BETA-HSD11, 17-BETA-HSDXI, DHRS8, PAN1B, RetSDR2, SDR16C2" ENSG00000198189 "Hydroxysteroid 17-beta dehydrogenase 11" Q8NBQ5 4 87336515-87391188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 280.6;liver: 234.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 360.6;Distal enterocytes: 353.9;Paneth cells: 458.7;Proximal enterocytes: 1083.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 772.2" "Group enriched" "Detected in all" 4 "granulocytes: 772.2;monocytes: 202.3" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021608 Enhanced Supported "Lipid droplets" "Intracellular and membrane" Enzyme NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 5: Enterocytes - Absorption" 54 "Lipid droplets" "HPA021608: AB_1847660" "unprognostic (4.53e-2)" "unprognostic (1.61e-1)" "unprognostic (2.35e-2)" "unprognostic (4.14e-2)" "unprognostic (9.68e-2)" "unprognostic (1.92e-1)" "unprognostic (3.35e-1)" "unprognostic (3.70e-2)" "unprognostic (1.78e-1)" "unprognostic (8.53e-2)" "unprognostic (1.24e-3)" "unprognostic (1.83e-1)" "unprognostic (2.65e-3)" "unprognostic (5.53e-2)" "unprognostic (2.13e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-2)" HTATIP2 "CC3, FLJ26963, SDR44U1, TIP30" ENSG00000109854 "HIV-1 Tat interactive protein 2" Q9BUP3 11 20363685-20383782 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Differentiation, Host-virus interaction" "Developmental protein, Oxidoreductase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 263.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006417, HPA024321" Approved Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 1 Cytosol "HPA006417: AB_1079091, HPA024321: AB_1851288" "unprognostic (8.05e-3)" "unprognostic (2.13e-1)" "unprognostic (9.31e-2)" "unprognostic (3.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.79e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.20e-3)" "unprognostic (1.05e-1)" "unprognostic (4.93e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.20e-1)" "unprognostic (9.42e-2)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" HYI HT036 ENSG00000178922 "Hydroxypyruvate isomerase (putative)" Q5T013 1 43450989-43453989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 185.1;Proximal enterocytes: 204.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 30.0" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Adrenocortical cancer: 190.2" "Low region specificity" "Detected in all" HPA040092 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 3: Basal prostatic cells - Lipid metabolism" 2 "Plasma membrane, Cytosol" "Golgi apparatus" "HPA040092: AB_10795374" "prognostic favorable (9.18e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.68e-2)" "unprognostic (3.86e-1)" "unprognostic (4.40e-2)" "prognostic unfavorable (5.55e-4)" "unprognostic (2.75e-2)" "unprognostic (1.42e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (2.75e-5)" "unprognostic (5.10e-2)" "unprognostic (7.93e-2)" "unprognostic (3.58e-2)" "prognostic favorable (2.72e-5)" HYKK "AGPHD1, LOC123688" ENSG00000188266 "Hydroxylysine kinase" A2RU49 15 78507564-78537372 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 31.6;Proximal enterocytes: 36.8;Proximal tubular cells: 30.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.0" "Lineage enriched" "Detected in single" 7 "T-cells: 3.0" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040706 Approved Approved Nucleoplasm,Vesicles,Aggresome,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoplasm, Vesicles, Aggresome, Cytosol" "HPA040706: AB_10795528" "unprognostic (9.26e-2)" "unprognostic (1.98e-4)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (2.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.00e-3)" "unprognostic (2.73e-1)" "unprognostic (5.16e-2)" "unprognostic (6.24e-3)" "unprognostic (6.37e-2)" "unprognostic (3.44e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (3.11e-3)" "unprognostic (3.90e-2)" IDNK "bA522I20.2, C9orf103, hGntK" ENSG00000148057 "IDNK gluconokinase" Q5T6J7 9 83623049-83644130 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 68.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 52.2;Hepatocytes: 55.3;Proximal enterocytes: 87.8;Proximal tubular cells: 174.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020378, HPA058429" Approved Approved Mitochondria,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 52: Kidney - Transmembrane transport" "Cluster 54: Immune cells - T cell receptor" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "Mitochondria, Cytosol" "HPA020378: AB_1845794, HPA058429: AB_2683716" "unprognostic (1.49e-3)" "unprognostic (7.94e-2)" "unprognostic (3.30e-1)" "prognostic favorable (1.10e-6)" "unprognostic (1.39e-1)" "unprognostic (1.56e-1)" "unprognostic (5.41e-3)" "unprognostic (1.81e-2)" "unprognostic (6.08e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-2)" "unprognostic (3.00e-1)" "unprognostic (5.86e-3)" "unprognostic (7.32e-2)" "unprognostic (1.07e-1)" "unprognostic (2.55e-1)" "unprognostic (3.11e-2)" IFI27 "FAM14D, ISG12, P27" ENSG00000165949 "Interferon alpha inducible protein 27" P40305 14 94104836-94116695 "Plasma proteins, Predicted membrane proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 3514.8;Distal enterocytes: 4034.6;Endothelial cells: 1661.3;Intestinal goblet cells: 2206.2;Paneth cells: 1871.2;Proximal enterocytes: 3099.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 8.2" "Group enriched" "Detected in many" 5 "monocytes: 8.2;T-cells: 3.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 766.6" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells" HPA028875 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 5: Enterocytes - Absorption" "HPA028875: AB_10601434" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (2.43e-2)" "unprognostic (6.68e-2)" "unprognostic (4.74e-2)" "unprognostic (1.59e-2)" "unprognostic (6.78e-3)" "unprognostic (5.26e-2)" "unprognostic (2.10e-1)" "prognostic favorable (8.80e-4)" "unprognostic (1.13e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" IFI35 IFP35 ENSG00000068079 "Interferon induced protein 35" P80217 17 43006740-43014456 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 132.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003283, HPA045946, HPA075580" Approved Supported Nucleoplasm,Nucleoli,Cytosol "Secreted to blood" Immunity NA NA 120000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 47: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 1 "Nucleoplasm, Cytosol" Nucleoli "HPA003283: , HPA045946: AB_2679509, HPA075580: " "prognostic favorable (1.41e-4)" "unprognostic (1.14e-2)" "unprognostic (1.82e-1)" "unprognostic (2.16e-1)" "unprognostic (1.32e-1)" "unprognostic (3.26e-1)" "unprognostic (3.90e-3)" "unprognostic (1.14e-1)" "unprognostic (6.92e-2)" "unprognostic (9.78e-3)" "unprognostic (6.51e-3)" "unprognostic (1.22e-1)" "prognostic unfavorable (4.03e-5)" "unprognostic (3.55e-1)" "unprognostic (3.62e-2)" "unprognostic (1.34e-2)" "unprognostic (1.49e-1)" IFNLR1 "CRF2/12, IFNLR, IL-28R1, IL28RA" ENSG00000185436 "Interferon lambda receptor 1" Q8IU57 1 24154168-24187959 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 13.3;dendritic cells: 14.7;Proximal enterocytes: 16.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 4.9;naive B-cell: 5.9;plasmacytoid DC: 11.4" "Group enriched" "Detected in many" 5 "B-cells: 5.9;dendritic cells: 11.4" "Cancer enhanced" "Detected in many" "lymphoma: 20.0" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017319 Uncertain Approved Cytosol "Intracellular and membrane" Receptor NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 28: Dendritic cells - Antigen presentation" 2 Cytosol "HPA017319: AB_1851708" "prognostic favorable (5.12e-4)" "unprognostic (7.16e-2)" "unprognostic (8.61e-3)" "unprognostic (8.48e-2)" "unprognostic (8.09e-2)" "unprognostic (1.22e-2)" "unprognostic (7.28e-3)" "unprognostic (2.33e-1)" "unprognostic (5.10e-2)" "unprognostic (1.93e-1)" "unprognostic (5.51e-2)" "unprognostic (4.50e-1)" "unprognostic (3.66e-3)" "unprognostic (5.15e-2)" "unprognostic (1.69e-1)" "unprognostic (2.69e-1)" "unprognostic (1.10e-1)" IGBP1 "alpha4, IBP1" ENSG00000089289 "Immunoglobulin binding protein 1" P78318 X 70133447-70166324 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" Chaperone "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 331.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000634, HPA001004, CAB034139" Approved Supported Cytosol NA NA 48000 "Cluster 31: T-cells - T-cell receptor" "Cluster 18: Non-specific - Ribosome" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 64: Non-specific - Ribosome" 8 Cytosol "CAB034139: AB_2295670, HPA000634: AB_1079102, HPA001004: AB_1079104" "unprognostic (3.59e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (5.35e-3)" "unprognostic (1.22e-2)" "unprognostic (1.11e-2)" "unprognostic (4.84e-3)" "unprognostic (2.21e-2)" "unprognostic (1.50e-1)" "unprognostic (2.22e-1)" "unprognostic (1.74e-1)" "unprognostic (3.00e-1)" "unprognostic (2.67e-2)" "unprognostic (1.46e-1)" "unprognostic (5.86e-2)" "unprognostic (1.42e-2)" "unprognostic (4.10e-3)" IHH "BDA1, HHG2" ENSG00000163501 "Indian hedgehog signaling molecule" Q14623 2 219054424-219060921 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 13.6;intestine: 21.7;stomach 1: 14.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 40.8;Enteroendocrine cells: 49.3;Gastric mucus-secreting cells: 12.4;Intestinal goblet cells: 40.6;Paneth cells: 13.9;Prostatic glandular cells: 17.1;Proximal enterocytes: 18.1;Undifferentiated cells: 18.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.8;endometrial cancer: 30.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 13.8;Gastric cancer: 11.1;liver cancer: 7.1" "Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" "Developmental protein" NA NA 23000000 "Cluster 45: Intestine - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.63e-2)" "prognostic favorable (3.67e-6)" "unprognostic (4.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.28e-1)" "unprognostic (1.06e-1)" "unprognostic (5.86e-2)" "unprognostic (2.74e-1)" "unprognostic (6.31e-2)" "unprognostic (3.33e-3)" "unprognostic (1.81e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-1)" "unprognostic (1.51e-2)" "unprognostic (2.91e-2)" IL10RB "CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2" ENSG00000243646 "Interleukin 10 receptor subunit beta" Q08334 21 33266367-33311420 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiviral defense" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 47.6;Paneth cells: 43.6;Proximal enterocytes: 54.4;Syncytiotrophoblasts: 52.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020670, HPA047550" Approved Approved Cytosol NA NA 1600000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 49: Non-specific - Transcription" 2 Cytosol "CAB020670: , HPA047550: AB_2680086" "unprognostic (8.43e-2)" "unprognostic (6.50e-2)" "unprognostic (5.88e-2)" "unprognostic (1.77e-1)" "unprognostic (1.48e-2)" "unprognostic (7.78e-2)" "unprognostic (1.97e-3)" "unprognostic (1.26e-1)" "unprognostic (5.69e-3)" "unprognostic (1.31e-1)" "unprognostic (1.19e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (5.62e-9)" "unprognostic (3.09e-1)" "unprognostic (2.76e-1)" "unprognostic (1.29e-2)" "unprognostic (1.05e-1)" IL17RC IL17-RL ENSG00000163702 "Interleukin 17 receptor C" Q8NAC3 3 9917074-9933630 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "HPA019885, CAB026255" Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 17: Breast glandular cells - Lactation" "CAB026255: , HPA019885: AB_1851664" "unprognostic (2.07e-1)" "unprognostic (2.02e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.38e-4)" "unprognostic (2.58e-2)" "unprognostic (1.45e-3)" "unprognostic (8.60e-2)" "unprognostic (7.11e-2)" "unprognostic (1.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.30e-2)" "unprognostic (5.98e-2)" "unprognostic (9.35e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "unprognostic (1.48e-1)" "unprognostic (2.83e-1)" IL17RE FLJ23658 ENSG00000163701 "Interleukin 17 receptor E" Q8NFR9 3 9902612-9916402 "Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.2;skin 1: 30.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 74.7;Enteroendocrine cells: 36.9;Gastric mucus-secreting cells: 49.5;Intestinal goblet cells: 63.4;Paneth cells: 41.7;Proximal enterocytes: 67.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 2.9;cerebellum: 4.0;hypothalamus: 1.3;medulla oblongata: 1.4;pons: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Alveolar cells type 1" "Region enhanced" "Detected in single" "cerebellum: 1.5" HPA019011 Uncertain "Intracellular and membrane" Receptor NA NA "Cluster 45: Intestine - Digestion" "Cluster 37: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA019011: AB_1851667" "unprognostic (1.08e-2)" "unprognostic (7.58e-2)" "unprognostic (2.06e-1)" "unprognostic (1.43e-3)" "unprognostic (1.09e-1)" "unprognostic (9.81e-2)" "unprognostic (1.50e-1)" "unprognostic (8.43e-2)" "unprognostic (6.69e-2)" "unprognostic (6.31e-2)" "unprognostic (3.55e-3)" "unprognostic (4.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.10e-1)" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-2)" IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 112.7;lymphoid tissue: 332.3" "Cell type enhanced" "Detected in many" "B-cells: 111.4;dendritic cells: 92.3;Distal enterocytes: 97.2;Langerhans cells: 150.0;NK-cells: 280.1;Plasma cells: 127.0;Proximal enterocytes: 79.5;T-cells: 192.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Leukemia: 207.1;lymphoma: 145.1;Myeloma: 354.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA046641, CAB080341" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA 13000 "Cluster 1: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" 6 "Nucleoplasm, Plasma membrane" "Endoplasmic reticulum" "CAB080341: , HPA046641: AB_2679733" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" IL32 "NK4, TAIF, TAIFb, TAIFd" ENSG00000008517 "Interleukin 32" P24001 16 3065297-3082192 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 808.7;pancreas: 654.9" "Cell type enhanced" "Detected in many" "Ductal cells: 1395.6;Exocrine glandular cells: 3125.9;Pancreatic endocrine cells: 3246.5;Proximal enterocytes: 4806.7;Proximal tubular cells: 5236.5;T-cells: 1635.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 4640.3" "Lineage enriched" "Detected in all" 8 "T-cells: 4640.3" "Cancer enhanced" "Detected in all" "Kidney cancer: 674.0" "HPA029397, CAB030029" Uncertain "Secreted to blood" Interleukin NA NA 46100 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Non-specific - Mixed function" "CAB030029: AB_1089175, HPA029397: AB_10612120" "unprognostic (2.00e-2)" "unprognostic (2.89e-2)" "unprognostic (2.86e-1)" "prognostic favorable (1.33e-4)" "unprognostic (2.95e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-2)" "unprognostic (2.58e-2)" "unprognostic (1.73e-3)" "unprognostic (2.19e-2)" "unprognostic (3.32e-3)" "unprognostic (3.51e-1)" "unprognostic (3.30e-2)" "unprognostic (8.08e-2)" "unprognostic (3.86e-2)" "unprognostic (3.16e-2)" "unprognostic (4.29e-3)" INAVA "C1orf106, FLJ10901" ENSG00000163362 "Innate immunity activator" Q3KP66 1 200891048-200915742 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.9;intestine: 53.9;skin 1: 45.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 109.7;Gastric mucus-secreting cells: 62.5;Intestinal goblet cells: 99.7;Paneth cells: 72.1;Proximal enterocytes: 150.4;Suprabasal keratinocytes: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA027499, HPA027511, HPA079622" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 4 Nucleoplasm "Nuclear bodies" "HPA027499: AB_10599708, HPA027511: AB_10600334, HPA079622: " "unprognostic (3.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.78e-5)" "unprognostic (4.56e-2)" "unprognostic (2.18e-1)" "unprognostic (2.74e-2)" "unprognostic (6.62e-3)" "unprognostic (2.84e-2)" "unprognostic (9.38e-2)" "unprognostic (2.52e-2)" "unprognostic (2.81e-1)" "unprognostic (3.23e-3)" "unprognostic (1.67e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.73e-2)" INPP5J "INPP5, PIB5PA, PIPP" ENSG00000185133 "Inositol polyphosphate-5-phosphatase J" Q15735 22 31122731-31134697 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 118.9;thyroid gland: 198.0" "Cell type enhanced" "Detected in many" "Collecting duct cells: 17.5;Distal enterocytes: 36.3;Inhibitory neurons: 18.8;Muller glia cells: 21.7;Paneth cells: 17.0;Proximal enterocytes: 60.0" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 63.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 12.3" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells" "Region enhanced" "Detected in all" "olfactory bulb: 131.0" "Low region specificity" "Detected in all" HPA034539 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 15 Cytosol "Nucleoli fibrillar center" "HPA034539: AB_10670974" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-2)" "unprognostic (2.21e-3)" "prognostic favorable (1.47e-5)" "unprognostic (6.81e-2)" "unprognostic (1.86e-2)" "unprognostic (4.29e-4)" "unprognostic (1.47e-1)" "prognostic favorable (1.12e-7)" "unprognostic (2.79e-3)" "unprognostic (3.65e-2)" "unprognostic (2.14e-1)" "unprognostic (1.39e-2)" IQSEC2 "BRAG1, IQ-ArfGEF, KIAA0522, MRX1, MRX18, MRX78" ENSG00000124313 "IQ motif and Sec7 domain ArfGEF 2" Q5JU85 X 53225828-53321350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 56.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 52.2;Late spermatids: 66.2;Proximal enterocytes: 43.7;Proximal tubular cells: 48.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 10.4;plasmacytoid DC: 10.6" "Group enriched" "Detected in many" 17 "dendritic cells: 10.6;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003973, HPA076533" Approved "Vesicles,Lipid droplets" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 34: Neurons - Neuronal signaling" "Vesicles, Lipid droplets" "HPA003973: AB_2280343, HPA076533: " "unprognostic (1.85e-1)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (1.32e-1)" "unprognostic (4.66e-3)" "unprognostic (6.02e-2)" "unprognostic (2.80e-1)" "unprognostic (3.78e-2)" "unprognostic (2.82e-1)" "unprognostic (9.05e-2)" "unprognostic (1.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.56e-2)" "unprognostic (1.75e-1)" "unprognostic (4.30e-2)" "prognostic favorable (2.38e-4)" ISG15 "G1P2, IFI15, UCRP" ENSG00000187608 "ISG15 ubiquitin like modifier" P05161 1 1001138-1014540 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 311.4" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 622.0;Hofbauer cells: 392.5;Lymphatic endothelial cells: 349.7;Proximal enterocytes: 533.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004627 Approved "Secreted to blood" Immunity NA NA 5000000 "Cluster 19: Eosinophils - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 5 "HPA004627: AB_1079152" "unprognostic (3.65e-1)" "unprognostic (1.06e-1)" "unprognostic (1.12e-2)" "unprognostic (4.62e-2)" "unprognostic (3.96e-3)" "unprognostic (1.38e-1)" "unprognostic (4.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.48e-2)" "unprognostic (3.78e-3)" "unprognostic (2.07e-3)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.11e-10)" "unprognostic (4.55e-2)" "unprognostic (4.13e-2)" "unprognostic (1.12e-2)" "unprognostic (7.46e-2)" ITPK1 ENSG00000100605 "Inositol-tetrakisphosphate 1-kinase" Q13572 14 92936914-93116320 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Isomerase, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 194.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 99.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 43.1" "Group enriched" "Detected in all" 5 "granulocytes: 43.1;monocytes: 26.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055230 Approved Approved Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Macrophages - Innate immune response" Mitochondria "HPA055230: AB_2682748" "unprognostic (1.93e-3)" "unprognostic (2.50e-1)" "unprognostic (2.15e-1)" "prognostic favorable (8.56e-4)" "unprognostic (4.27e-1)" "unprognostic (2.04e-2)" "unprognostic (6.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.24e-2)" "unprognostic (2.86e-2)" "unprognostic (8.14e-2)" "unprognostic (2.27e-1)" "unprognostic (1.37e-3)" "unprognostic (2.39e-1)" "unprognostic (2.02e-1)" "unprognostic (4.20e-1)" "unprognostic (7.25e-3)" ITPKA "IP3-3KA, IP3KA" ENSG00000137825 "Inositol-trisphosphate 3-kinase A" P23677 15 41493393-41503551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.5;intestine: 17.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 59.0;Early spermatids: 43.8;Excitatory neurons: 22.9;Gastric mucus-secreting cells: 30.1;Late spermatids: 165.8;Proximal enterocytes: 33.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 11 "T-cells: 1.4" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "amygdala: 11.2;basal ganglia: 44.1;cerebral cortex: 33.5;hippocampal formation: 29.2" HPA040454 Enhanced Approved Approved "Vesicles,Plasma membrane" No No "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 63: Late spermatids - Spermatogenesis" Vesicles "Plasma membrane" "HPA040454: AB_10672897" "unprognostic (5.91e-2)" "unprognostic (2.16e-3)" "unprognostic (4.19e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.77e-4)" "unprognostic (2.25e-2)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.76e-9)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-3)" "unprognostic (2.10e-2)" KAZALD1 "FKSG28, FKSG40" ENSG00000107821 "Kazal type serine peptidase inhibitor domain 1" Q96I82 10 101061989-101068131 "Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.9;Gastric mucus-secreting cells: 33.6;Intestinal goblet cells: 63.8;Proximal enterocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 28.7" "Kidney - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011800 Uncertain "Secreted to extracellular matrix" "Developmental protein" NA NA 65000 "Cluster 47: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA011800: AB_1852082" "unprognostic (3.34e-1)" "unprognostic (8.86e-3)" "unprognostic (1.16e-2)" "unprognostic (4.43e-3)" "unprognostic (4.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.35e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (3.44e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (2.11e-1)" KBTBD11 "KIAA0711, KLHDC7C" ENSG00000176595 "Kelch repeat and BTB domain containing 11" O94819 8 1973677-2006936 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 34.0;Distal enterocytes: 33.7;Lymphatic endothelial cells: 76.8;Proximal enterocytes: 60.7" "Cancer enhanced" "Detected in many" "renal cancer: 14.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051159 Uncertain Approved "Intermediate filaments" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Intermediate filaments" "HPA051159: AB_2681367" "unprognostic (1.19e-1)" "unprognostic (2.27e-1)" "unprognostic (1.20e-3)" "unprognostic (2.70e-2)" "unprognostic (2.03e-1)" "unprognostic (6.84e-2)" "unprognostic (2.76e-4)" "unprognostic (2.50e-2)" "unprognostic (1.06e-1)" "unprognostic (5.68e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (4.75e-2)" "unprognostic (9.53e-2)" "unprognostic (3.52e-2)" "unprognostic (1.75e-1)" "unprognostic (1.04e-2)" KCNH6 "erg2, HERG2, Kv11.2" ENSG00000173826 "Potassium voltage-gated channel subfamily H member 6" Q9H252 17 63523334-63548977 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.7;kidney: 6.8;pituitary gland: 5.2;prostate: 3.8;retina: 4.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 42.1;Cone photoreceptor cells: 11.9;Enteroendocrine cells: 27.3;Horizontal cells: 11.3;Prostatic glandular cells: 24.5;Proximal enterocytes: 40.9" "Cancer enhanced" "Detected in some" "prostate cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 6.2;lung cancer: 9.7;prostate cancer: 5.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.4;olfactory bulb: 3.2;spinal cord: 3.2" HPA061704 Approved NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" "HPA061704: " "unprognostic (8.00e-2)" "unprognostic (1.80e-1)" "unprognostic (5.46e-2)" "unprognostic (5.68e-2)" "unprognostic (5.98e-5)" "unprognostic (3.39e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-1)" "unprognostic (1.28e-2)" "unprognostic (3.25e-1)" "unprognostic (1.74e-3)" "unprognostic (3.95e-1)" "unprognostic (1.19e-1)" "unprognostic (9.80e-2)" "unprognostic (3.66e-1)" "unprognostic (8.05e-2)" "unprognostic (9.15e-2)" KCNK5 "K2p5.1, TASK-2, TASK2" ENSG00000164626 "Potassium two pore domain channel subfamily K member 5" O95279 6 39188971-39229475 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.4;kidney: 36.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 53.4;Cytotrophoblasts: 28.2;Distal enterocytes: 43.4;Proximal enterocytes: 55.6;Salivary duct cells: 34.9;Syncytiotrophoblasts: 40.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059148 Uncertain Approved Nucleoplasm NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 24 Nucleoplasm "HPA059148: AB_2683929" "unprognostic (1.46e-1)" "prognostic favorable (3.29e-4)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (8.09e-4)" "unprognostic (3.97e-2)" "unprognostic (2.33e-1)" "unprognostic (9.57e-3)" "unprognostic (7.14e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (2.98e-1)" "prognostic favorable (4.98e-7)" "unprognostic (2.34e-1)" "unprognostic (7.13e-2)" "unprognostic (1.03e-2)" "prognostic favorable (4.45e-4)" KIAA2013 "MGC33867, RP5-1077B9.1" ENSG00000116685 KIAA2013 Q8IYS2 1 11919591-11926428 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052677, HPA060536" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 22: Proximal enterocytes - Digestion" 2 "Golgi apparatus" Cytosol "HPA052677: AB_2681911, HPA060536: AB_2684313" "unprognostic (3.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.63e-2)" "unprognostic (1.48e-1)" "unprognostic (2.02e-2)" "unprognostic (1.87e-2)" "unprognostic (5.51e-3)" "unprognostic (8.60e-2)" "unprognostic (5.26e-2)" "unprognostic (2.92e-1)" "unprognostic (1.10e-2)" "unprognostic (5.04e-2)" "unprognostic (6.05e-2)" "unprognostic (2.04e-2)" "unprognostic (2.94e-2)" "unprognostic (8.24e-3)" "unprognostic (3.74e-3)" KIF12 ENSG00000136883 "Kinesin family member 12" 9 114086126-114099292 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 147.2;pancreas: 79.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 118.3;Collecting duct cells: 66.1;Distal tubular cells: 76.8;Ductal cells: 50.3;Enteroendocrine cells: 76.5;Proximal enterocytes: 42.0;Proximal tubular cells: 73.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 23.3;liver cancer: 14.7" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020192, HPA024127" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Golgi apparatus, Plasma membrane" "HPA020192: AB_1852467, HPA024127: AB_1852469" "unprognostic (5.29e-2)" "unprognostic (5.03e-2)" "unprognostic (3.34e-1)" "unprognostic (1.84e-2)" "unprognostic (5.80e-2)" "unprognostic (8.38e-2)" "unprognostic (9.81e-2)" "unprognostic (4.41e-2)" "unprognostic (1.90e-1)" "unprognostic (3.98e-2)" "unprognostic (1.69e-2)" "unprognostic (3.33e-2)" "unprognostic (1.10e-2)" "unprognostic (4.51e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" KLC4 "bA387M24.3, KNSL8" ENSG00000137171 "Kinesin light chain 4" Q9NSK0 6 43040777-43075095 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 84.1;Hepatocytes: 62.1;Paneth cells: 68.0;Proximal enterocytes: 133.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030168, HPA030169" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 18 Mitochondria Cytosol "HPA030168: AB_10599285, HPA030169: AB_10601105" "unprognostic (2.96e-2)" "unprognostic (6.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.08e-2)" "unprognostic (3.67e-2)" "unprognostic (5.63e-3)" "unprognostic (6.36e-3)" "unprognostic (1.19e-2)" "unprognostic (4.67e-2)" "unprognostic (1.30e-1)" "unprognostic (1.47e-2)" "unprognostic (9.22e-2)" "prognostic favorable (6.99e-6)" "unprognostic (2.08e-1)" "unprognostic (3.93e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" KRT12 K12 ENSG00000187242 "Keratin 12" Q99456 17 40861303-40867223 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal enterocytes: 5.4;Intestinal goblet cells: 1.5;Late spermatids: 1.8;Paneth cells: 8.5;Proximal enterocytes: 1.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.0" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055217, HPA055835" Enhanced NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 5: Enterocytes - Absorption" "HPA055217: AB_2682742, HPA055835: AB_2682935" "unprognostic (1.89e-1)" "unprognostic (2.40e-2)" "unprognostic (1.01e-1)" "unprognostic (4.82e-1)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.74e-2)" "unprognostic (5.52e-2)" "unprognostic (9.41e-3)" "unprognostic (3.49e-1)" "unprognostic (1.73e-1)" "unprognostic (3.94e-3)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (2.60e-4)" "unprognostic (6.31e-3)" KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 864.1;salivary gland: 786.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 6850.6;Club cells: 5440.4;Distal enterocytes: 7654.8;Extravillous trophoblasts: 8032.7;Proximal enterocytes: 8878.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 13.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 4070.4" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 62.5" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 300000000 "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 65 "Intermediate filaments" "CAB000031: AB_2234418, HPA002465: AB_1079179" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.86e-2)" "unprognostic (1.59e-2)" "unprognostic (2.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (3.14e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.82e-5)" "unprognostic (1.90e-2)" "prognostic unfavorable (2.98e-5)" "unprognostic (3.52e-2)" "unprognostic (2.14e-1)" "unprognostic (3.08e-2)" "unprognostic (2.35e-2)" KRT8 "CARD2, CK-8, CK8, CYK8, K2C8, K8, KO" ENSG00000170421 "Keratin 8" P05787 12 52897187-52949954 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1323.0;stomach 1: 793.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 12319.1;Ductal cells: 5203.4;Extravillous trophoblasts: 6075.3;Paneth cells: 8520.4;Proximal enterocytes: 7547.1;Syncytiotrophoblasts: 5966.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 12 "spinal cord: 64.6" "CAB000131, CAB001696, HPA049866" Enhanced Supported "Intermediate filaments" NA NA 1700000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 20 "Intermediate filaments" "CAB000131: AB_2281144, CAB001696: , HPA049866: AB_2680923" "unprognostic (5.72e-2)" "unprognostic (2.29e-1)" "unprognostic (2.49e-2)" "unprognostic (1.52e-1)" "unprognostic (2.76e-2)" "unprognostic (4.86e-3)" "unprognostic (3.10e-2)" "unprognostic (2.52e-2)" "unprognostic (1.92e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (8.99e-2)" "unprognostic (2.08e-2)" "unprognostic (2.83e-2)" "unprognostic (3.18e-1)" "unprognostic (3.68e-1)" "unprognostic (1.19e-2)" KRTCAP3 KCP3 ENSG00000157992 "Keratinocyte associated protein 3" Q53RY4 2 27442366-27446481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 153.5;Proximal enterocytes: 170.2;Undifferentiated cells: 179.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "MAIT T-cell: 6.8;memory B-cell: 4.5;memory CD4 T-cell: 5.7;memory CD8 T-cell: 2.6;naive B-cell: 6.5;naive CD4 T-cell: 6.6;naive CD8 T-cell: 2.7;T-reg: 4.4" "Group enriched" "Detected in many" 13 "B-cells: 6.5;T-cells: 6.8" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA047136, HPA060203" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "Nucleoplasm, Cytosol" "HPA047136: AB_2679949, HPA060203: AB_2684221" "prognostic favorable (2.67e-5)" "unprognostic (5.93e-2)" "unprognostic (5.03e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-1)" "unprognostic (7.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (9.43e-2)" "unprognostic (1.60e-2)" "unprognostic (1.44e-2)" "unprognostic (4.63e-2)" "unprognostic (1.04e-1)" "unprognostic (3.73e-3)" "unprognostic (3.79e-2)" "unprognostic (8.21e-2)" "unprognostic (9.42e-3)" LAD1 ENSG00000159166 "Ladinin 1" O00515 1 201380833-201399915 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 352.0;skin 1: 208.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 151.4;Distal enterocytes: 143.5;Ductal cells: 156.4;Oocytes: 146.3;Proximal enterocytes: 232.2;Squamous epithelial cells: 213.2;Suprabasal keratinocytes: 354.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 257.9" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA007256, HPA028732" Enhanced Enhanced "Actin filaments" "Secreted to extracellular matrix" "No annotated function" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" "Actin filaments" "HPA007256: AB_1852681, HPA028732: AB_10602916" "unprognostic (4.95e-2)" "unprognostic (2.05e-1)" "unprognostic (3.82e-1)" "unprognostic (7.55e-3)" "unprognostic (4.66e-2)" "unprognostic (7.41e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.71e-2)" "unprognostic (9.11e-2)" "unprognostic (2.31e-2)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (6.40e-2)" "unprognostic (3.28e-1)" LAMA1 LAMA ENSG00000101680 "Laminin subunit alpha 1" P25391 18 6941742-7117797 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.2;testis: 5.7" "Cell type enhanced" "Detected in many" "Astrocytes: 86.1;Distal enterocytes: 151.5;Granulosa cells: 27.5;Intestinal goblet cells: 43.2;Paneth cells: 38.4;Proximal enterocytes: 44.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 34.9" "Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010179 Enhanced "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 19: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" "CAB010179: AB_2133741" "unprognostic (2.75e-1)" "unprognostic (3.66e-4)" "unprognostic (2.08e-1)" "unprognostic (3.56e-1)" "unprognostic (4.97e-3)" "unprognostic (3.66e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (2.23e-2)" "unprognostic (3.43e-2)" "unprognostic (3.02e-1)" "unprognostic (6.80e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-2)" "unprognostic (4.85e-1)" "unprognostic (3.47e-2)" "unprognostic (7.34e-3)" LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 588.6;Proximal enterocytes: 277.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 9400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" 21 "Plasma membrane, Cytosol" "Focal adhesion sites" "CAB022049: , HPA012072: AB_1852714" "unprognostic (1.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-1)" "unprognostic (9.60e-2)" "unprognostic (9.87e-3)" "unprognostic (1.01e-1)" "unprognostic (9.65e-3)" "unprognostic (1.29e-3)" "unprognostic (3.95e-2)" "unprognostic (1.60e-3)" "unprognostic (4.53e-2)" LENG9 ENSG00000275183 "Leukocyte receptor cluster member 9" 19 54461732-54463778 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 28.0" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 39.7;Proximal enterocytes: 56.6;Rod photoreceptor cells: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051671, HPA053556" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 68: Non-specific - Protein processing" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoli fibrillar center" "HPA051671: AB_2681568, HPA053556: AB_2682187" "unprognostic (8.38e-2)" "unprognostic (8.60e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.99e-5)" "unprognostic (2.43e-2)" "unprognostic (2.21e-3)" "unprognostic (1.09e-1)" "unprognostic (4.88e-2)" "unprognostic (5.73e-2)" "unprognostic (1.94e-1)" "unprognostic (7.40e-2)" "unprognostic (2.04e-1)" "unprognostic (1.10e-3)" "unprognostic (1.63e-3)" "unprognostic (2.96e-1)" "unprognostic (9.12e-2)" "unprognostic (2.76e-2)" LGALS2 HL14 ENSG00000100079 "Galectin 2" P05162 22 37570248-37582616 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 324.0;intestine: 192.3;kidney: 146.8;pancreas: 204.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 889.1;Distal enterocytes: 888.5;Langerhans cells: 1119.4;Proximal enterocytes: 2780.2;Proximal tubular cells: 1672.8" "Cancer enhanced" "Detected in all" "renal cancer: 54.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 27 "classical monocyte: 1470.6;intermediate monocyte: 555.0;myeloid DC: 1211.4" "Group enriched" "Detected in all" 50 "dendritic cells: 1211.4;monocytes: 1470.6" "Cancer enhanced" "Detected in many" "Gastric cancer: 36.8;liver cancer: 20.7" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Exocrine glandular cells, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003536, CAB025198" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 48: Stomach - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" 4 Mitochondria Nucleoplasm "CAB025198: , HPA003536: AB_1078936" "unprognostic (1.37e-3)" "unprognostic (4.11e-3)" "unprognostic (1.32e-3)" "unprognostic (4.32e-2)" "unprognostic (1.74e-1)" "unprognostic (2.91e-3)" "unprognostic (3.19e-1)" "unprognostic (9.92e-2)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.15e-2)" "unprognostic (5.19e-1)" "unprognostic (2.33e-3)" "unprognostic (1.80e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (1.21e-1)" LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1154.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 8373.5;Paneth cells: 4392.4;Proximal enterocytes: 4885.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 652.7;intermediate monocyte: 545.4;myeloid DC: 398.3;non-classical monocyte: 443.7;T-reg: 252.7" "Group enriched" "Detected in all" 13 "dendritic cells: 398.3;monocytes: 652.7;T-cells: 252.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA NA 1900000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 13 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: AB_2136784, HPA003162: AB_1078937, HPA076528: " "unprognostic (1.42e-1)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.73e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-3)" "unprognostic (5.97e-2)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.96e-2)" "unprognostic (2.65e-3)" "unprognostic (7.60e-3)" LGALS3BP "90K, BTBD17B, CyCAP, gp90, M2BP, MAC-2-BP, TANGO10B" ENSG00000108679 "Galectin 3 binding protein" Q08380 17 78971238-78979947 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 533.0;Proximal enterocytes: 869.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "monocytes: 27.2;T-cells: 68.6" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000410, HPA000554" Uncertain "Secreted to blood" "Cell adhesion" NA NA 7100000000 "Cluster 11: T-cells - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 5: Enterocytes - Absorption" 6 "HPA000410: , HPA000554: AB_1079246" "unprognostic (1.23e-2)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.63e-3)" "unprognostic (1.62e-2)" "unprognostic (1.68e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (1.57e-2)" "unprognostic (4.55e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (1.58e-1)" "unprognostic (1.65e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-2)" LIPH "LPDLR, mPA-PLA1, mPA-PLA1alpha, PLA1B" ENSG00000163898 "Lipase H" Q8WWY8 3 185506262-185552588 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.5;stomach 1: 47.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 152.9;Gastric mucus-secreting cells: 172.1;Granulosa cells: 101.5;Intestinal goblet cells: 159.8;Ionocytes: 397.6;Proximal enterocytes: 138.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 39.7;pancreatic cancer: 33.3" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Pancreas - Ductal cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA049079 Approved "Secreted to blood" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA049079: AB_2680623" "unprognostic (4.50e-3)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (3.38e-1)" "unprognostic (1.01e-1)" "unprognostic (8.59e-2)" "unprognostic (1.44e-1)" "unprognostic (8.67e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (7.88e-2)" "prognostic favorable (9.20e-5)" "unprognostic (1.84e-1)" "unprognostic (1.97e-1)" "prognostic favorable (4.21e-4)" "unprognostic (1.15e-1)" LPCAT3 "C3F, LPLAT12, MBOAT5, nessy, OACT5" ENSG00000111684 "Lysophosphatidylcholine acyltransferase 3" Q6P1A2 12 6976185-7018477 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 101.6;Proximal enterocytes: 121.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 2, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "unprognostic (1.74e-1)" "unprognostic (3.33e-2)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (6.72e-2)" "unprognostic (3.86e-1)" "unprognostic (2.40e-2)" "unprognostic (6.90e-2)" "unprognostic (1.88e-1)" "unprognostic (5.00e-3)" "unprognostic (2.06e-1)" "unprognostic (2.58e-2)" "prognostic favorable (4.89e-5)" "unprognostic (1.13e-1)" "unprognostic (2.21e-1)" "unprognostic (6.49e-3)" "unprognostic (1.23e-1)" LPIN3 "LIPN3L, SMP2" ENSG00000132793 "Lipin 3" Q9BQK8 20 41340821-41360582 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 205.4;Proximal enterocytes: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA051466, HPA052667, HPA070640" Approved Supported Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Late spermatids - Spermatogenesis" Cytosol "HPA051466: , HPA052667: AB_2681908, HPA070640: AB_2686288" "unprognostic (2.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (9.74e-4)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (6.91e-3)" "unprognostic (4.26e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.74e-4)" "unprognostic (4.29e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (5.60e-3)" "unprognostic (2.02e-1)" "unprognostic (1.35e-1)" "unprognostic (3.37e-3)" LRRC66 ENSG00000188993 "Leucine rich repeat containing 66" Q68CR7 4 51993652-52020363 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 21.4;skeletal muscle: 7.6" "Cell type enhanced" "Detected in some" "Astrocytes: 5.6;Distal enterocytes: 9.2;Excitatory neurons: 9.1;Inhibitory neurons: 7.1;Oligodendrocyte precursor cells: 7.5;Oligodendrocytes: 8.1;Paneth cells: 5.3;Proximal enterocytes: 19.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014549, HPA027839" Uncertain NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA014549: AB_1853062, HPA027839: AB_10602705" "unprognostic (1.10e-1)" "unprognostic (4.87e-2)" "unprognostic (8.62e-2)" "unprognostic (2.34e-1)" "unprognostic (1.41e-1)" "unprognostic (1.87e-1)" "unprognostic (2.57e-2)" "unprognostic (4.83e-3)" "unprognostic (2.93e-1)" "unprognostic (4.09e-3)" "unprognostic (1.61e-2)" "unprognostic (1.89e-1)" "unprognostic (6.31e-3)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (3.05e-1)" "unprognostic (4.06e-1)" LRRC75B "C22orf36, FAM211B, MGC131773" ENSG00000178026 "Leucine rich repeat containing 75B" Q2VPJ9 22 24585620-24593208 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 8.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.4;Muller glia cells: 34.3;Proximal enterocytes: 45.8;Proximal tubular cells: 37.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002540 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoplasm, Cytosol" "HPA002540: AB_1079263" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.47e-1)" "unprognostic (2.34e-1)" "unprognostic (2.74e-2)" "unprognostic (5.21e-2)" "unprognostic (4.52e-2)" "unprognostic (2.48e-2)" "unprognostic (2.49e-1)" "unprognostic (2.48e-2)" "unprognostic (2.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (7.40e-2)" "unprognostic (9.69e-2)" MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Intellectual disability, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 255.8;Inhibitory neurons: 363.0;Kupffer cells: 382.8;Lymphatic endothelial cells: 281.1;Proximal enterocytes: 279.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Cancer enriched" "Detected in many" 7 "Myeloma: 58.6" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "Nucleoplasm, Nuclear bodies" Vesicles "CAB010296: AB_638562, HPA028289: AB_10602024" "unprognostic (6.76e-2)" "unprognostic (1.74e-2)" "unprognostic (6.45e-2)" "unprognostic (7.65e-2)" "unprognostic (7.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (2.33e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (4.54e-2)" "unprognostic (7.83e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" MALL BENE ENSG00000144063 "Mal, T cell differentiation protein like" Q13021 2 110083870-110116022 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 358.1;intestine: 228.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.3;Alveolar cells type 2: 238.9;Distal enterocytes: 653.1;Ductal cells: 277.7;Paneth cells: 207.2;Proximal enterocytes: 768.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 8.2;neutrophil: 2.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051410 Uncertain NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 51 "HPA051410: AB_2681474" "unprognostic (5.17e-1)" "unprognostic (4.15e-2)" "unprognostic (2.92e-1)" "unprognostic (3.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (4.46e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (2.37e-1)" "unprognostic (7.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.84e-1)" "unprognostic (2.80e-1)" "unprognostic (6.50e-3)" MAMDC4 "AEGP, DKFZp434M1411, EDTB" ENSG00000177943 "MAM domain containing 4" Q6UXC1 9 136850943-136860799 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.5;liver: 29.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 28.7;Hepatocytes: 20.4;Intestinal goblet cells: 23.3;Proximal enterocytes: 23.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Low region specificity" "Detected in all" "CAB026377, HPA059977" Approved Nucleoplasm,Cytosol NA Yes "Cluster 69: Liver - Oxidoreductase activity" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm Cytosol "CAB026377: , HPA059977: AB_2684186" "unprognostic (2.79e-1)" "unprognostic (7.90e-2)" "unprognostic (4.09e-3)" "unprognostic (6.86e-2)" "unprognostic (8.33e-2)" "unprognostic (2.66e-4)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (7.37e-2)" "prognostic favorable (1.88e-6)" "unprognostic (8.22e-3)" "unprognostic (1.58e-2)" "unprognostic (1.22e-3)" "unprognostic (9.22e-2)" "unprognostic (2.18e-1)" "unprognostic (1.08e-2)" MAOA ENSG00000189221 "Monoamine oxidase A" P21397 X 43654907-43746817 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" Oxidoreductase "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 213.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 309.6;Proximal enterocytes: 817.1;Proximal tubular cells: 517.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 47.6;prostate cancer: 69.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009437, HPA054807, HPA059299" Enhanced Supported Mitochondria,Cytosol No No "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 50: Lymphoma - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 Mitochondria Cytosol "CAB009437: AB_2137260, HPA054807: AB_2682607, HPA059299: AB_2683970" "unprognostic (9.54e-3)" "unprognostic (1.63e-1)" "unprognostic (7.99e-2)" "unprognostic (3.07e-1)" "unprognostic (6.75e-2)" "unprognostic (3.32e-1)" "unprognostic (9.51e-2)" "unprognostic (6.89e-3)" "unprognostic (2.21e-1)" "unprognostic (4.29e-2)" "unprognostic (3.94e-1)" "unprognostic (3.54e-1)" "unprognostic (1.45e-3)" "unprognostic (1.16e-2)" "unprognostic (1.47e-1)" "unprognostic (4.04e-2)" "unprognostic (2.98e-3)" MAOB ENSG00000069535 "Monoamine oxidase B" P27338 X 43766610-43882450 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 308.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 130.1;granulocytes: 213.3;Hepatocytes: 210.6;Ovarian stromal cells: 154.7;Proximal enterocytes: 179.7;Proximal tubular cells: 142.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 36.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002328, CAB037200" Enhanced NA NA 110000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 6: Ovarian stromal cells - Transcription" 14 "CAB037200: AB_1841012, HPA002328: AB_1854062" "unprognostic (1.19e-2)" "unprognostic (1.36e-1)" "unprognostic (5.16e-2)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.69e-2)" "unprognostic (5.61e-2)" "unprognostic (4.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (9.74e-2)" "unprognostic (5.35e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (1.90e-3)" MAPK13 "p38delta, PRKM13, SAPK4" ENSG00000156711 "Mitogen-activated protein kinase 13" O15264 6 36127809-36144524 "Enzymes, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 99.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 145.1;Late spermatids: 277.2;Proximal enterocytes: 180.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Region enriched" "Detected in all" 14 "cerebellum: 41.0" "HPA007667, CAB025854" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 17: Breast glandular cells - Lactation" 2 "Nucleoplasm, Nucleoli, Nucleoli rim, Cytosol" "CAB025854: , HPA007667: AB_1079867" "unprognostic (6.36e-2)" "unprognostic (6.88e-2)" "unprognostic (2.93e-1)" "unprognostic (6.64e-3)" "unprognostic (1.13e-2)" "unprognostic (4.80e-2)" "unprognostic (4.30e-3)" "unprognostic (5.28e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-1)" "unprognostic (7.21e-2)" "prognostic favorable (9.00e-4)" "unprognostic (3.12e-2)" "unprognostic (1.70e-1)" "unprognostic (2.21e-2)" "unprognostic (1.41e-1)" MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 313.7;Late spermatids: 263.1;Proximal enterocytes: 227.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 49.2;neutrophil: 21.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 49.2" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Supported Nucleoplasm NA NA 46000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 17 Nucleoplasm "CAB002683: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (5.03e-2)" "unprognostic (4.62e-2)" "unprognostic (3.46e-2)" "unprognostic (1.60e-1)" "unprognostic (4.70e-3)" "unprognostic (2.75e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (2.09e-2)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (3.51e-2)" "unprognostic (8.78e-2)" "unprognostic (1.45e-1)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (1.19e-2)" MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 99.3;Intestinal goblet cells: 61.6;Paneth cells: 92.8;Proximal enterocytes: 197.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Outer root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "Intermediate filaments" "HPA043514: AB_10959475, HPA045471: " "unprognostic (1.18e-1)" "unprognostic (3.92e-1)" "unprognostic (9.92e-2)" "unprognostic (5.56e-2)" "unprognostic (1.03e-1)" "unprognostic (6.16e-3)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (2.54e-1)" "unprognostic (8.75e-3)" "unprognostic (3.29e-1)" "unprognostic (5.16e-2)" "prognostic favorable (6.80e-10)" "unprognostic (2.63e-3)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "unprognostic (2.43e-1)" MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 113.8;Late spermatids: 106.7;Peritubular cells: 252.9;Proximal enterocytes: 109.1;Schwann cells: 270.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" "No annotated function" NA NA 1500000 "Cluster 1: T-cells - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 2 "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" MCRIP2 "C16orf14, FAM195A, MGC15416" ENSG00000172366 "MAPK regulated corepressor interacting protein 2" Q9BUT9 16 636817-648474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 46.5;liver: 54.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 279.6;Late spermatids: 523.4;Proximal enterocytes: 278.4;Proximal tubular cells: 271.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060363 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "HPA060363: AB_2684263" "unprognostic (7.14e-2)" "unprognostic (3.85e-2)" "unprognostic (8.25e-2)" "unprognostic (2.49e-2)" "unprognostic (2.72e-1)" "unprognostic (4.18e-2)" "unprognostic (1.60e-1)" "unprognostic (2.96e-3)" "unprognostic (7.82e-2)" "unprognostic (3.14e-1)" "unprognostic (2.19e-2)" "unprognostic (1.10e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.06e-2)" "unprognostic (4.00e-2)" "unprognostic (2.10e-2)" "prognostic favorable (7.23e-4)" MDK "FLJ27379, MK, NEGF2" ENSG00000110492 Midkine P21741 11 46380756-46383837 "Cancer-related genes, Predicted secreted proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 588.2" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 656.5;Granulosa cells: 739.5;Ovarian stromal cells: 1036.0;Paneth cells: 1087.7;Proximal enterocytes: 793.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.8;neutrophil: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010055, HPA057126" Uncertain Approved Vesicles "Secreted to blood" "Growth factor" NA NA 158000 960000 "Cluster 62: Connective tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 9 Vesicles "CAB010055: AB_627949, HPA057126: AB_2683344" "unprognostic (8.87e-3)" "unprognostic (6.65e-2)" "unprognostic (4.02e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.90e-1)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.11e-2)" "unprognostic (4.01e-2)" "unprognostic (4.15e-1)" "prognostic unfavorable (3.06e-6)" "unprognostic (8.78e-2)" "unprognostic (1.31e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" METTL7B "ALDI, MGC17301" ENSG00000170439 "Methyltransferase like 7B" Q6UX53 12 55681736-55684611 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 130.4;heart muscle: 119.9;liver: 277.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 29.8;Distal enterocytes: 40.3;Hepatocytes: 73.8;Hofbauer cells: 65.1;Proximal enterocytes: 197.3;Proximal tubular cells: 32.3" "Cancer enhanced" "Detected in many" "glioma: 97.9;liver cancer: 97.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 4.5;myeloid DC: 7.0;naive B-cell: 1.7;non-classical monocyte: 3.3" "Group enriched" "Detected in many" 44 "B-cells: 1.7;dendritic cells: 7.0;monocytes: 4.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 44.0" "Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038644 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" Microtubules Vesicles "HPA038644: AB_2676130" "unprognostic (7.54e-2)" "unprognostic (7.15e-2)" "unprognostic (5.55e-2)" "unprognostic (3.07e-3)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-2)" "unprognostic (5.33e-2)" "unprognostic (2.64e-1)" "unprognostic (2.76e-2)" "unprognostic (7.10e-2)" "prognostic favorable (2.37e-4)" "unprognostic (2.43e-1)" MFSD2A "FLJ14490, MFSD2, SLC59A1" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 95.3;liver: 158.0;skin 1: 85.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 297.1;Basal prostatic cells: 213.4;Hepatocytes: 290.7;Proximal enterocytes: 201.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.4" "Group enriched" "Detected in many" 12 "dendritic cells: 24.4;monocytes: 13.2" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 3: Basal prostatic cells - Lipid metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" MGAT3 GNT-III ENSG00000128268 "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase" Q09327 22 39457012-39492194 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.2;intestine: 27.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 28.3;Excitatory neurons: 24.3;Horizontal cells: 27.7;Inhibitory neurons: 26.2;Late spermatids: 26.4;Oligodendrocyte precursor cells: 20.3;Oligodendrocytes: 42.5;Proximal enterocytes: 32.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4;eosinophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Myeloma: 58.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017598 Approved "Intracellular and membrane" Enzyme NA NA 170000 "Cluster 22: Eosinophils - Transcription" "Cluster 65: Cerebellum - Nervous system development" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA017598: AB_1853853" "unprognostic (1.41e-3)" "unprognostic (5.98e-3)" "unprognostic (4.79e-2)" "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (5.71e-3)" "unprognostic (8.92e-2)" "unprognostic (2.17e-1)" "unprognostic (4.35e-3)" "unprognostic (6.77e-2)" "unprognostic (8.12e-3)" "unprognostic (8.74e-2)" "prognostic unfavorable (5.04e-8)" "unprognostic (6.73e-2)" "unprognostic (1.46e-1)" "unprognostic (5.89e-2)" "unprognostic (4.92e-2)" MGAT4A "GnT-4a, GnT-Iva" ENSG00000071073 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A" Q9UM21 2 98619106-98731132 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 94.8" "Cell type enhanced" "Detected in all" "Microglial cells: 167.3;NK-cells: 141.3;Proximal enterocytes: 129.1;T-cells: 116.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007608 Enhanced Approved "Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 11: T-cells - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Golgi apparatus" "HPA007608: AB_10602008" "prognostic unfavorable (4.30e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.48e-8)" "unprognostic (1.35e-1)" "unprognostic (2.28e-2)" "unprognostic (3.82e-3)" "unprognostic (1.89e-1)" "unprognostic (3.76e-1)" "unprognostic (3.58e-1)" "unprognostic (2.80e-2)" "unprognostic (2.32e-2)" "unprognostic (4.17e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.04e-2)" "unprognostic (2.04e-1)" MGAT4B GnT-Ivb ENSG00000161013 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B" Q9UQ53 5 179797597-179806952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 270.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 209.2;Proximal enterocytes: 212.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 5.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.5" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012804, HPA052134" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA 19000 "Cluster 19: Eosinophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 2 Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA012804: , HPA052134: AB_2681741" "unprognostic (2.01e-2)" "unprognostic (8.68e-3)" "unprognostic (1.40e-1)" "unprognostic (3.83e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (3.61e-3)" "unprognostic (7.57e-3)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (5.13e-2)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "prognostic favorable (5.78e-4)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.42e-1)" MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 380.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 453.5;Proximal enterocytes: 443.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 195.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010690, HPA010707" Enhanced Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 12: Squamous epithelial cells - Keratinization" 22 Cytosol "Endoplasmic reticulum" "HPA010690: , HPA010707: AB_1853922" "unprognostic (9.35e-2)" "unprognostic (6.13e-2)" "unprognostic (4.33e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.58e-1)" "unprognostic (8.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (4.38e-2)" "unprognostic (2.77e-2)" "unprognostic (8.78e-2)" "unprognostic (6.41e-2)" "prognostic favorable (3.22e-9)" "unprognostic (4.10e-1)" "unprognostic (9.91e-2)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" MICALL2 "FLJ23471, JRAB, MGC46023, MICAL-L2" ENSG00000164877 "MICAL like 2" Q8IY33 7 1428465-1459470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 97.8;Distal enterocytes: 65.0;Gastric mucus-secreting cells: 153.9;Oocytes: 88.2;Proximal enterocytes: 59.8;Schwann cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 33.8" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA025695 Enhanced NA NA "Cluster 47: Spleen - Immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 67: Non-specific - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 6 "HPA025695: AB_10610140" "unprognostic (2.46e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-2)" "unprognostic (6.01e-3)" "unprognostic (2.23e-3)" "unprognostic (3.51e-2)" "unprognostic (9.02e-3)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (6.40e-2)" "unprognostic (1.03e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (6.53e-9)" "unprognostic (1.95e-1)" "unprognostic (4.63e-2)" "unprognostic (1.46e-1)" "unprognostic (3.84e-2)" MKRN2OS "C3orf83, MKRN2-AS1" ENSG00000225526 "MKRN2 opposite strand" H3BPM6 3 12514934-12561059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 6.9;intestine: 6.9" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 13.4;Paneth cells: 14.6;Proximal enterocytes: 23.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 6.3" "Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA065586, HPA065753" Uncertain Approved "Golgi apparatus" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" "Golgi apparatus" "HPA065586: AB_2685514, HPA065753: AB_2685553" "unprognostic (2.53e-2)" "unprognostic (1.01e-2)" "unprognostic (3.89e-3)" "unprognostic (2.03e-3)" "unprognostic (3.81e-1)" "unprognostic (8.45e-2)" "unprognostic (2.24e-1)" "unprognostic (2.29e-1)" "unprognostic (5.26e-2)" "unprognostic (3.86e-2)" "unprognostic (1.58e-2)" "unprognostic (4.29e-3)" "unprognostic (2.53e-5)" "unprognostic (1.02e-1)" "unprognostic (2.48e-1)" "unprognostic (8.50e-3)" "unprognostic (3.17e-3)" MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 324.3;kidney: 292.0" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 76.6;Cytotrophoblasts: 78.8;Endometrial stromal cells: 269.5;Prostatic glandular cells: 119.5;Proximal enterocytes: 322.6;Syncytiotrophoblasts: 127.2" "Cancer enhanced" "Detected in many" "prostate cancer: 17.6" "Region enhanced" "Detected in all" "basal ganglia: 37.9" "Immune cell enriched" "Detected in some" 123 "neutrophil: 139.9" "Lineage enriched" "Detected in many" 123 "granulocytes: 139.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Fibroblasts, Kidney - Podocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Region enhanced" "Detected in all" "basal ganglia: 43.8" "CAB000013, HPA052583, HPA056072" Enhanced NA NA 320000 "Cluster 35: Neutrophils - Protein binding" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 74: Neutrophils - Degranulation" 3 "CAB000013: AB_563478, HPA052583: AB_2681872, HPA056072: AB_2683027" "unprognostic (1.36e-1)" "unprognostic (1.02e-3)" "unprognostic (8.52e-2)" "unprognostic (2.95e-1)" "unprognostic (2.78e-2)" "unprognostic (6.52e-3)" "unprognostic (1.20e-1)" "unprognostic (1.67e-2)" "unprognostic (8.67e-2)" "unprognostic (1.96e-1)" "unprognostic (7.30e-3)" "unprognostic (1.31e-1)" "unprognostic (2.71e-3)" "unprognostic (1.50e-1)" "unprognostic (7.29e-2)" "unprognostic (1.06e-2)" "unprognostic (1.37e-2)" MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 51.5;Distal enterocytes: 88.5;Extravillous trophoblasts: 53.6;Proximal enterocytes: 59.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 5: Enterocytes - Absorption" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: AB_2676956" "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favorable (3.08e-4)" MMP28 "EPILYSIN, MM28, MMP-25, MMP-28" ENSG00000271447 "Matrix metallopeptidase 28" Q9H239 17 35756249-35795707 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 92.0;Alveolar cells type 2: 76.4;Distal enterocytes: 146.7;Paneth cells: 58.3;Proximal enterocytes: 77.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "naive CD4 T-cell: 6.3;naive CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 6.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 55.6" "Breast - Adipocytes (Breast), Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 21: Testis - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 1 "unprognostic (7.99e-3)" "unprognostic (3.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (6.90e-2)" "unprognostic (1.09e-2)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.28e-6)" "unprognostic (9.37e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (3.27e-3)" MOCOS "FLJ20733, HMCS, MOS" ENSG00000075643 "Molybdenum cofactor sulfurase" Q96EN8 18 36187497-36272157 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 9.9;liver: 15.6" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 19.4;Hepatocytes: 33.7;Proximal enterocytes: 22.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039412, HPA047958" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 2 Mitochondria Cytosol "HPA039412: AB_2676496, HPA047958: AB_2680225" "unprognostic (3.07e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (3.18e-3)" "unprognostic (2.55e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.84e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.91e-2)" "prognostic unfavorable (3.03e-12)" "unprognostic (8.98e-2)" "unprognostic (2.37e-1)" "unprognostic (4.09e-1)" "unprognostic (6.35e-2)" MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 73.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 350000 "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 5: Enterocytes - Absorption" Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" MPND FLJ14981 ENSG00000008382 "MPN domain containing" Q8N594 19 4343527-4360086 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 73.3;Proximal enterocytes: 49.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043274, HPA045475" Approved Approved "Nucleoplasm,Nucleoli rim" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 37: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 58: Macrophages - Innate immune response" 15 "Nucleoli rim" Nucleoplasm "HPA043274: AB_2678403, HPA045475: AB_2679339" "unprognostic (3.16e-2)" "prognostic favorable (2.99e-4)" "unprognostic (4.85e-2)" "prognostic favorable (6.12e-4)" "unprognostic (8.60e-2)" "unprognostic (5.37e-3)" "unprognostic (3.16e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.23e-1)" "unprognostic (2.87e-2)" "unprognostic (3.94e-3)" "unprognostic (5.18e-2)" "prognostic favorable (7.04e-4)" "unprognostic (2.22e-3)" "unprognostic (3.22e-1)" "unprognostic (5.44e-2)" "unprognostic (9.04e-2)" MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029821 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 381.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 609.4;Hepatocytes: 610.0;Paneth cells: 516.0;Proximal enterocytes: 1316.9;Proximal tubular cells: 460.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001240 Enhanced Approved Mitochondria,Cytosol NA NA 2900000 "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 25: Non-specific - Ribosome" "Cluster 5: Enterocytes - Absorption" 1 Mitochondria Cytosol "HPA001240: AB_1079408" "unprognostic (7.18e-3)" "unprognostic (4.45e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-3)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (7.07e-2)" "unprognostic (2.15e-1)" "unprognostic (2.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-3)" "unprognostic (3.98e-2)" "unprognostic (3.51e-1)" "unprognostic (2.52e-1)" "prognostic favorable (5.89e-4)" MRO "B29, C18orf3, FLJ30140" ENSG00000134042 Maestro Q9BYG7 18 50795120-50825402 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 29.8;kidney: 23.2;testis: 28.1" "Cell type enhanced" "Detected in some" "Astrocytes: 28.5;Kupffer cells: 12.2;Proximal enterocytes: 22.2;Proximal tubular cells: 9.3;Sertoli cells: 35.4" "Cancer enriched" "Detected in some" 7 "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.9" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022011 Approved NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA022011: AB_2670880" "unprognostic (9.21e-5)" "unprognostic (5.22e-2)" "unprognostic (7.87e-3)" "unprognostic (1.45e-2)" "unprognostic (2.47e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-2)" "unprognostic (5.11e-2)" "unprognostic (3.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.32e-1)" "unprognostic (4.71e-1)" "unprognostic (5.15e-3)" "unprognostic (1.14e-1)" "unprognostic (3.99e-3)" "unprognostic (6.06e-4)" MST1R "CD136, CDw136, PTK8, RON, SEA" ENSG00000164078 "Macrophage stimulating 1 receptor" Q04912 3 49887002-49903873 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.8;skin 1: 31.1;stomach 1: 26.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.7;Distal enterocytes: 32.8;Gastric mucus-secreting cells: 92.0;Intestinal goblet cells: 25.9;Proximal enterocytes: 21.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 49.5" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007657, HPA008180, CAB008972" Enhanced Approved Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Gastric mucus-secreting cells - Digestion" 3 Cytosol "CAB008972: , HPA007657: AB_1079292, HPA008180: AB_1079291" "unprognostic (3.84e-3)" "unprognostic (3.86e-1)" "unprognostic (1.92e-1)" "unprognostic (7.33e-3)" "unprognostic (3.82e-2)" "unprognostic (2.32e-1)" "unprognostic (8.07e-3)" "unprognostic (1.54e-2)" "unprognostic (4.12e-2)" "unprognostic (2.15e-1)" "unprognostic (1.24e-3)" "unprognostic (2.28e-1)" "unprognostic (8.08e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-1)" "unprognostic (8.00e-3)" "prognostic favorable (2.33e-5)" MT-CO1 "COI, COX1, MTCO1" ENSG00000198804 "Mitochondrially encoded cytochrome c oxidase I" P00395 MT 5904-7445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Deafness, Disease variant, Leber hereditary optic neuropathy, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 247736.1;tongue: 177371.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 66649.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016241, HPA069328" Enhanced Supported Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 Mitochondria "CAB016241: AB_2229888, HPA069328: AB_2686122" "unprognostic (4.39e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (2.21e-1)" "unprognostic (1.59e-1)" "unprognostic (3.31e-1)" "prognostic favorable (2.29e-4)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.56e-3)" "unprognostic (1.20e-2)" "unprognostic (6.60e-2)" "unprognostic (2.83e-2)" "unprognostic (5.06e-3)" "unprognostic (4.50e-2)" "unprognostic (2.15e-2)" "unprognostic (2.44e-2)" MT-ND2 "MTND2, NAD2, ND2" ENSG00000198763 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2" P03891 MT 4470-5511 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Alzheimer disease, Amyloidosis, Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 110717.6;heart muscle: 126601.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 32821.9;Proximal enterocytes: 18329.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 16897.8" "Lineage enriched" "Detected in all" 10 "granulocytes: 16897.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 68: Cardiomyocytes - Muscle contraction" "unprognostic (5.82e-3)" "unprognostic (1.58e-2)" "unprognostic (1.53e-2)" "unprognostic (1.36e-1)" "unprognostic (4.77e-1)" "unprognostic (4.79e-2)" "unprognostic (9.56e-3)" "unprognostic (3.74e-2)" "unprognostic (2.18e-1)" "unprognostic (3.38e-3)" "unprognostic (4.55e-3)" "unprognostic (3.79e-2)" "unprognostic (4.35e-2)" "unprognostic (3.94e-2)" "unprognostic (2.11e-1)" "unprognostic (5.92e-2)" "unprognostic (4.35e-2)" MT1E "MT1, MTD" ENSG00000169715 "Metallothionein 1E" P04732 16 56625475-56627112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1743.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3045.1;Hepatocytes: 4440.6;Paneth cells: 5072.2;Proximal enterocytes: 6171.7;Proximal tubular cells: 10127.9;Undifferentiated cells: 2644.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 5.9;T-cells: 21.1" "Low cancer specificity" "Detected in many" HPA041152 Approved Approved Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Nucleoplasm "HPA041152: AB_2732490" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.77e-2)" "unprognostic (1.19e-2)" "unprognostic (3.63e-1)" "unprognostic (9.80e-2)" "unprognostic (7.85e-2)" "unprognostic (3.45e-2)" "unprognostic (2.78e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (5.06e-5)" "unprognostic (1.86e-1)" "unprognostic (9.53e-2)" "unprognostic (1.97e-1)" "unprognostic (3.78e-2)" MT1M "MT1, MT1K" ENSG00000205364 "Metallothionein 1M" Q8N339 16 56632659-56633981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 386.1;liver: 548.4" "Cell type enhanced" "Detected in many" "Adipocytes: 1286.1;Distal enterocytes: 954.3;Glandular and luminal cells: 1266.0;Hepatocytes: 1814.8;Paneth cells: 1358.9;Proximal enterocytes: 1153.7;Smooth muscle cells: 678.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 25.3;ovarian cancer: 27.8" "Colon - Neutrophils, Skin - Macrophages" NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" 6 "unprognostic (1.83e-2)" "unprognostic (2.49e-1)" "unprognostic (2.10e-2)" "unprognostic (3.10e-2)" "unprognostic (4.19e-3)" "unprognostic (7.73e-2)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.13e-4)" "unprognostic (4.67e-2)" "unprognostic (3.10e-1)" "unprognostic (3.55e-1)" "unprognostic (3.68e-2)" "unprognostic (1.25e-1)" "unprognostic (3.50e-2)" "unprognostic (1.34e-2)" "unprognostic (4.71e-2)" MT1X "MT-1l, MT1" ENSG00000187193 "Metallothionein 1X" P80297 16 56682470-56684196 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 3931.5;skeletal muscle: 5884.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 9865.2;Paneth cells: 3112.6;Proximal enterocytes: 3597.3;Proximal tubular cells: 13083.1;Skeletal myocytes: 3156.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 2 "unprognostic (8.15e-2)" "unprognostic (9.02e-2)" "unprognostic (8.27e-2)" "unprognostic (1.18e-3)" "unprognostic (7.05e-3)" "unprognostic (7.26e-3)" "unprognostic (9.49e-3)" "unprognostic (9.69e-2)" "unprognostic (1.35e-1)" "unprognostic (4.40e-2)" "unprognostic (4.85e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-10)" "unprognostic (1.56e-1)" "unprognostic (4.25e-2)" "unprognostic (4.11e-1)" "unprognostic (1.37e-3)" MT2A MT2 ENSG00000125148 "Metallothionein 2A" P02795 16 56608584-56609497 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 5644.8" "Cell type enhanced" "Detected in many" "Adipocytes: 8176.2;Hepatocytes: 22593.0;monocytes: 15392.9;Paneth cells: 8229.8;Proximal enterocytes: 10323.3;Proximal tubular cells: 20157.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 83: Liver - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 13 "unprognostic (1.14e-1)" "unprognostic (8.90e-2)" "unprognostic (2.11e-1)" "unprognostic (1.65e-1)" "unprognostic (1.76e-1)" "unprognostic (4.89e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (5.74e-5)" "unprognostic (5.69e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (9.52e-4)" "unprognostic (8.59e-2)" "prognostic unfavorable (2.92e-9)" "unprognostic (4.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.42e-1)" "unprognostic (1.03e-2)" MTARC2 "FLJ20605, MARC2, MOSC2" ENSG00000117791 "Mitochondrial amidoxime reducing component 2" Q969Z3 1 220748225-220784815 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 127.2;liver: 216.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.5;Proximal enterocytes: 61.9" "Cancer enhanced" "Detected in all" "liver cancer: 35.9" "Region enriched" "Detected in all" 5 "choroid plexus: 109.4" "Immune cell enriched" "Detected in some" 6 "basophil: 14.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 14.2" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015085, HPA017572" Enhanced NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "HPA015085: AB_1848780, HPA017572: AB_1848778" "unprognostic (8.17e-2)" "unprognostic (1.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.40e-10)" "unprognostic (4.78e-2)" "unprognostic (2.67e-2)" "unprognostic (2.78e-1)" "unprognostic (1.90e-1)" "unprognostic (2.05e-2)" "prognostic favorable (3.09e-4)" "unprognostic (1.45e-1)" "unprognostic (1.81e-1)" "unprognostic (2.39e-2)" "unprognostic (6.23e-2)" MTMR11 CRA ENSG00000014914 "Myotubularin related protein 11" A4FU01 1 149928651-149936879 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 119.3;Enteroendocrine cells: 44.2;Intestinal goblet cells: 100.3;Paneth cells: 77.1;Proximal enterocytes: 103.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.3;myeloid DC: 1.7;non-classical monocyte: 1.3" "Group enriched" "Detected in many" 16 "dendritic cells: 1.7;monocytes: 1.3" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030351, HPA072906" Enhanced Approved Centrosome NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 45: Non-specific - Mixed function" Centrosome "HPA030351: AB_10602185, HPA072906: " "unprognostic (1.14e-1)" "unprognostic (3.01e-3)" "unprognostic (1.42e-1)" "unprognostic (1.22e-2)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.37e-2)" "unprognostic (5.81e-2)" "unprognostic (7.94e-2)" "unprognostic (2.98e-1)" "unprognostic (2.88e-2)" "unprognostic (1.22e-1)" "unprognostic (5.83e-2)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (1.80e-2)" "unprognostic (9.12e-2)" MUC3A MUC3 ENSG00000169894 "Mucin 3A, cell surface associated" Q02505 7 100949534-100968347 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 13.4;intestine: 40.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 179.2;Intestinal goblet cells: 179.0;Paneth cells: 140.9;Proximal enterocytes: 383.1;Undifferentiated cells: 115.8" "Group enriched" "Detected in many" 5 "colorectal cancer: 16.4;pancreatic cancer: 14.0;stomach cancer: 29.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 8.3;Gastric cancer: 3.8" "Region enriched" "Detected in many" 7 "cerebellum: 16.5" "HPA010871, HPA047868" Uncertain Uncertain "Cell Junctions" "Intracellular and membrane" "No annotated function" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 1: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "Cell Junctions" "HPA010871: AB_1854201, HPA047868: " "unprognostic (1.12e-2)" "unprognostic (3.78e-2)" "unprognostic (1.75e-1)" "unprognostic (4.22e-3)" "unprognostic (2.91e-1)" "unprognostic (5.16e-2)" "unprognostic (2.06e-1)" "unprognostic (5.29e-3)" "unprognostic (2.87e-1)" "unprognostic (1.33e-1)" "unprognostic (7.01e-2)" "unprognostic (2.99e-1)" "unprognostic (6.50e-3)" "unprognostic (8.73e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (4.51e-2)" MVP "LRP, VAULT1" ENSG00000013364 "Major vault protein" Q14764 16 29820394-29848039 "Cancer-related genes, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" Ribonucleoprotein "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 534.1;Proximal enterocytes: 512.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002321, CAB002752, CAB022717, HPA064740" Enhanced Supported Cytosol NA NA 110000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 4 Cytosol "CAB002752: , CAB022717: , HPA002321: AB_1079277, HPA064740: AB_2685342" "prognostic favorable (4.51e-4)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (8.17e-2)" "unprognostic (3.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.22e-2)" "unprognostic (6.03e-3)" "unprognostic (2.19e-1)" "unprognostic (6.85e-3)" "unprognostic (2.86e-1)" "prognostic favorable (5.49e-5)" "unprognostic (2.22e-1)" "unprognostic (5.19e-2)" "unprognostic (5.69e-3)" "unprognostic (2.65e-2)" MYH14 "DFNA4, FLJ13881, KIAA2034, MHC16, MYH17" ENSG00000105357 "Myosin heavy chain 14" Q7Z406 19 50188186-50310542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 72.6;skeletal muscle: 100.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 370.2;Paneth cells: 206.2;Proximal enterocytes: 357.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062391, HPA067889, HPA070260" Enhanced Approved Nucleoplasm NA NA 9600000 "Cluster 19: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 1 Nucleoplasm "HPA062391: AB_2684748, HPA067889: AB_2685917, HPA070260: AB_2686243" "unprognostic (2.52e-1)" "unprognostic (5.81e-2)" "unprognostic (9.63e-2)" "unprognostic (3.73e-3)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.71e-1)" "unprognostic (3.48e-2)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "prognostic favorable (3.97e-8)" "prognostic favorable (7.83e-4)" "unprognostic (8.50e-2)" "unprognostic (3.12e-1)" "unprognostic (2.77e-1)" MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195164 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 60.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 79.2;Distal enterocytes: 129.6;Inhibitory neurons: 87.2;Proximal enterocytes: 176.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 3 "Plasma membrane" "HPA040593: AB_10795525, HPA040902: AB_10796230, HPA069773: AB_2686194" "unprognostic (2.51e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-2)" "unprognostic (6.17e-3)" "unprognostic (2.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.26e-5)" "unprognostic (4.48e-2)" "prognostic favorable (1.45e-11)" "unprognostic (2.17e-3)" "unprognostic (1.50e-1)" "unprognostic (6.56e-2)" "unprognostic (3.28e-1)" MYORG "KIAA1161, NET37" ENSG00000164976 "Myogenesis regulating glycosidase (putative)" Q6NSJ0 9 34366666-34376898 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.1" "Cell type enhanced" "Detected in many" "Astrocytes: 39.0;Cholangiocytes: 26.7;Cytotrophoblasts: 55.3;Distal enterocytes: 47.9;Hepatocytes: 45.9;Paneth cells: 28.7;Proximal enterocytes: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060533, HPA067487" Enhanced Approved Mitochondria NA NA "Cluster 19: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Cytotrophoblasts - Mitochondria" Mitochondria "HPA060533: AB_2684311, HPA067487: AB_2685848" "unprognostic (6.56e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (2.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.68e-3)" "unprognostic (1.91e-3)" "unprognostic (3.20e-1)" "prognostic favorable (1.20e-13)" "unprognostic (4.08e-3)" "unprognostic (3.68e-1)" "unprognostic (3.09e-1)" "unprognostic (1.00e-3)" NAAA ASAHL ENSG00000138744 "N-acylethanolamine acid amidase" Q02083 4 75913660-75941013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 204.2;Prostatic glandular cells: 147.2;Proximal enterocytes: 149.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 31.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 671.9;non-classical monocyte: 585.2" "Lineage enriched" "Detected in all" 5 "monocytes: 671.9" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB026135 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" "CAB026135: " "unprognostic (5.30e-3)" "unprognostic (1.23e-2)" "unprognostic (1.41e-2)" "prognostic favorable (1.93e-4)" "unprognostic (1.10e-1)" "unprognostic (2.17e-2)" "unprognostic (2.92e-2)" "unprognostic (2.34e-2)" "unprognostic (2.24e-1)" "unprognostic (2.87e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.63e-1)" "unprognostic (2.15e-2)" "unprognostic (2.54e-1)" "unprognostic (3.20e-2)" "unprognostic (3.42e-3)" "unprognostic (6.21e-2)" NAPRT "NAPRT1, PP3856" ENSG00000147813 "Nicotinate phosphoribosyltransferase" Q6XQN6 8 143574785-143578649 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.5" "Cell type enhanced" "Detected in all" "Distal enterocytes: 338.9;Proximal enterocytes: 632.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023739, HPA024017, CAB068206, CAB068207" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 2300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB068206: AB_2665644, CAB068207: AB_2665681, HPA023739: AB_1854308, HPA024017: AB_1854309" "unprognostic (7.08e-2)" "unprognostic (1.55e-1)" "unprognostic (5.76e-3)" "unprognostic (2.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.30e-1)" "unprognostic (7.65e-2)" "unprognostic (2.19e-1)" "unprognostic (2.84e-1)" "unprognostic (1.08e-2)" "unprognostic (1.75e-1)" "unprognostic (4.13e-2)" "prognostic favorable (6.28e-4)" "unprognostic (6.02e-2)" "unprognostic (3.97e-1)" "unprognostic (2.28e-2)" "unprognostic (1.61e-2)" NBL1 "D1S1733E, DAN, DAND1, NB, NO3" ENSG00000158747 "NBL1, DAN family BMP antagonist" P41271 1 19596979-19658456 "Predicted intracellular proteins, Predicted secreted proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 654.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 342.1;Leydig cells: 405.4;Ovarian stromal cells: 526.2;Peritubular cells: 374.8;Proximal enterocytes: 407.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Vascular Endothelial cells, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007394, CAB026132" Uncertain "Secreted in other tissues" "No annotated function" NA NA 8100000 "Cluster 11: T-cells - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 6: Ovarian stromal cells - Transcription" 2 "CAB026132: , HPA007394: AB_10601272" "unprognostic (1.65e-1)" "unprognostic (1.65e-2)" "unprognostic (9.03e-2)" "unprognostic (2.85e-1)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (3.92e-1)" "unprognostic (7.88e-2)" "unprognostic (3.10e-2)" "unprognostic (1.92e-2)" "unprognostic (1.39e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (6.21e-2)" "unprognostic (2.26e-2)" NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 528.2;Proximal enterocytes: 388.6;Suprabasal keratinocytes: 755.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 414.2" "Colon - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported Microtubules,Cytosol NA NA 200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" 12 Cytosol Microtubules "HPA006881: AB_1078392" "unprognostic (6.96e-3)" "unprognostic (3.31e-3)" "unprognostic (8.53e-2)" "unprognostic (1.41e-3)" "unprognostic (1.54e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.04e-3)" "unprognostic (5.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.09e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.13e-4)" "unprognostic (7.27e-2)" "unprognostic (1.91e-1)" "unprognostic (2.47e-3)" "unprognostic (4.28e-2)" NDUFA13 "B16.6, CDA016, CGI-39, GRIM-19, GRIM19" ENSG00000186010 "NADH:ubiquinone oxidoreductase subunit A13" Q9P0J0 19 19515736-19529054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Electron transport, Host-virus interaction, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1119.9;Late spermatids: 2382.4;Proximal enterocytes: 1111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041213 Supported Supported Mitochondria NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" 3 Mitochondria "HPA041213: AB_10794988" "unprognostic (2.87e-1)" "unprognostic (2.88e-3)" "unprognostic (9.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.36e-2)" "unprognostic (5.78e-2)" "unprognostic (6.00e-2)" "unprognostic (3.30e-2)" "unprognostic (2.81e-1)" "unprognostic (1.83e-3)" "unprognostic (1.26e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-2)" "unprognostic (1.33e-1)" "unprognostic (2.37e-1)" "unprognostic (2.15e-2)" "unprognostic (2.15e-2)" NDUFA7 B14.5a ENSG00000267855 "NADH:ubiquinone oxidoreductase subunit A7" O95182 19 8308768-8321375 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 167.6;Distal tubular cells: 172.1;Pancreatic endocrine cells: 157.9;Proximal enterocytes: 186.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059251, HPA071866" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 16: Intestinal goblet cells - Mucin production" 4 Mitochondria "HPA059251: AB_2683960, HPA071866: AB_2686465" "unprognostic (6.55e-2)" "unprognostic (1.02e-3)" "unprognostic (1.11e-1)" "unprognostic (3.85e-1)" "unprognostic (2.18e-1)" "unprognostic (5.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.43e-2)" "unprognostic (3.40e-1)" "unprognostic (1.13e-3)" "unprognostic (1.81e-2)" "unprognostic (1.43e-1)" "unprognostic (1.09e-2)" "unprognostic (5.53e-2)" "unprognostic (1.29e-2)" "unprognostic (2.59e-2)" "unprognostic (9.35e-3)" NEURL1B "DKFZP761M1511, Neur2, RNF67B" ENSG00000214357 "Neuralized E3 ubiquitin protein ligase 1B" A8MQ27 5 172641263-172691540 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 76.2;Distal enterocytes: 57.4;Endothelial cells: 48.6;Leydig cells: 54.7;Paneth cells: 37.2;Proximal enterocytes: 50.8;Smooth muscle cells: 50.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037612 Approved Supported "Actin filaments,Cytosol" NA Yes "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 48: Smooth muscle cells - Signal transduction" Cytosol "Actin filaments" "HPA037612: AB_10795573" "unprognostic (3.56e-2)" "unprognostic (8.46e-2)" "unprognostic (6.72e-3)" "unprognostic (2.70e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-1)" "unprognostic (6.58e-2)" "unprognostic (2.95e-1)" "unprognostic (2.86e-1)" "unprognostic (1.09e-1)" "unprognostic (7.13e-3)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.00e-6)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (4.67e-2)" "unprognostic (3.22e-3)" NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 54.5;brain: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.1;Excitatory neurons: 102.4;Proximal enterocytes: 57.7" "Cancer enhanced" "Detected in many" "testis cancer: 22.5" "Group enriched" "Detected in all" 4 "basal ganglia: 380.4;cerebral cortex: 233.6;white matter: 165.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 219.2;cerebral cortex: 173.3;hippocampal formation: 95.4" HPA008160 Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Neurons - Neuronal signaling" 8 "Plasma membrane, Cytosol" "HPA008160: AB_1854450" "unprognostic (3.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-3)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-3)" "unprognostic (5.41e-3)" "unprognostic (2.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-1)" NIT1 ENSG00000158793 "Nitrilase 1" Q86X76 1 161118086-161125445 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 102.0;Proximal tubular cells: 104.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006656, HPA006657" Approved Approved Mitochondria,Cytosol NA NA 89000 "Cluster 29: Non-specific - Unknown function" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 22: Proximal enterocytes - Digestion" "Mitochondria, Cytosol" "HPA006656: , HPA006657: AB_1079485" "unprognostic (3.66e-2)" "unprognostic (1.15e-1)" "unprognostic (7.16e-2)" "unprognostic (1.39e-1)" "unprognostic (1.47e-1)" "unprognostic (1.10e-2)" "unprognostic (1.55e-1)" "unprognostic (2.16e-1)" "unprognostic (4.70e-2)" "unprognostic (2.52e-3)" "unprognostic (2.18e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (4.21e-4)" "unprognostic (2.00e-1)" "unprognostic (1.76e-1)" "unprognostic (2.52e-2)" "unprognostic (2.94e-2)" NOXA1 "FLJ25475, NY-CO-31, SDCCAG31" ENSG00000188747 "NADPH oxidase activator 1" Q86UR1 9 137423350-137434406 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 36.7;Gastric mucus-secreting cells: 52.5;Proximal enterocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 44.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044781 Uncertain Approved Vesicles NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 Vesicles "HPA044781: AB_10960532" "unprognostic (2.15e-1)" "unprognostic (2.86e-1)" "unprognostic (1.55e-3)" "unprognostic (1.42e-3)" "unprognostic (4.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.79e-1)" "unprognostic (3.99e-3)" "unprognostic (2.72e-1)" "unprognostic (1.69e-1)" "unprognostic (5.45e-3)" "unprognostic (1.97e-3)" "prognostic favorable (2.65e-4)" "unprognostic (4.97e-3)" "unprognostic (2.67e-1)" "unprognostic (1.74e-1)" "unprognostic (3.10e-2)" NR0B2 SHP ENSG00000131910 "Nuclear receptor subfamily 0 group B member 2" Q15466 1 26911489-26913975 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Receptor, Repressor" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.6;liver: 139.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 83.9;Ductal cells: 33.5;Exocrine glandular cells: 32.7;Gastric mucus-secreting cells: 99.0;Hepatocytes: 208.0;Proximal enterocytes: 39.6" "Cancer enriched" "Detected in many" 5 "liver cancer: 52.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 11.0;liver cancer: 16.0" "Kidney - Intercalated cells, Lung - Alveolar cells type 2" "Region enriched" "Detected in single" 6 "cerebellum: 1.7" "Not detected" "Not detected" HPA003983 Supported Nucleoplasm,Vesicles NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Hepatocytes - Metabolism" 8 Nucleoplasm Vesicles "HPA003983: " "unprognostic (2.99e-2)" "unprognostic (1.86e-1)" "unprognostic (1.95e-3)" "unprognostic (4.68e-3)" "unprognostic (9.21e-2)" "unprognostic (8.22e-2)" "unprognostic (3.97e-2)" "unprognostic (2.44e-2)" "unprognostic (1.83e-1)" "unprognostic (3.09e-1)" "unprognostic (2.11e-2)" "unprognostic (6.74e-3)" "unprognostic (1.04e-1)" "unprognostic (2.03e-1)" "unprognostic (4.12e-3)" "unprognostic (1.10e-2)" NR1H3 "LXR-a, LXRa, RLD-1" ENSG00000025434 "Nuclear receptor subfamily 1 group H member 3" Q13133 11 47248300-47269033 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 58.2;Kupffer cells: 76.3;Late spermatids: 47.4;Proximal enterocytes: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 13.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036443, CAB037109" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 11: Liver - Plasma proteins" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 58: Macrophages - Innate immune response" 10 Nucleoplasm Cytosol "CAB037109: AB_1840991, HPA036443: AB_10966142" "unprognostic (2.95e-3)" "unprognostic (5.31e-3)" "unprognostic (5.19e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.19e-1)" "unprognostic (2.65e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.51e-1)" "unprognostic (1.76e-1)" "unprognostic (7.73e-2)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (3.56e-1)" "unprognostic (4.42e-2)" "unprognostic (2.84e-1)" "prognostic favorable (3.40e-4)" NR1H4 "FXR, HRR-1, HRR1, RIP14" ENSG00000012504 "Nuclear receptor subfamily 1 group H member 4" Q96RI1 12 100473708-100564414 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.1;liver: 116.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 89.7;Granulosa cells: 87.5;Hepatocytes: 109.1;Oocytes: 59.6;Proximal enterocytes: 336.8;Proximal tubular cells: 149.8" "Group enriched" "Detected in some" 11 "liver cancer: 18.7;renal cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 3.8;Kidney cancer: 14.8;liver cancer: 12.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047699 Approved Nucleoplasm NA NA "Cluster 83: Liver - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 2 Nucleoplasm "HPA047699: AB_10965320" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (6.68e-2)" "unprognostic (2.49e-1)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (2.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.16e-1)" "unprognostic (2.43e-1)" "unprognostic (3.77e-3)" NUCB1 "Calnuc, NUC" ENSG00000104805 "Nucleobindin 1" Q02818 19 48900050-48923473 "Plasma proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 458.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008176 Supported Supported "Golgi apparatus,Microtubules" "Secreted to blood" Other NA NA 27000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Proximal enterocytes - Digestion" 1 "Golgi apparatus" Microtubules "HPA008176: AB_1845923" "unprognostic (2.13e-1)" "unprognostic (2.83e-1)" "unprognostic (4.36e-3)" "unprognostic (6.28e-2)" "unprognostic (1.06e-2)" "unprognostic (2.95e-1)" "unprognostic (6.86e-2)" "unprognostic (1.98e-1)" "unprognostic (9.51e-2)" "unprognostic (8.14e-3)" "unprognostic (2.34e-3)" "unprognostic (9.89e-2)" "unprognostic (5.04e-3)" "unprognostic (1.19e-1)" "unprognostic (1.39e-1)" "unprognostic (8.90e-3)" "unprognostic (3.41e-1)" NUDT14 UGPP ENSG00000183828 "Nudix hydrolase 14" O95848 14 105172938-105181323 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 213.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046755, HPA058759" Approved Approved Nucleoli,Microtubules NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 22: Proximal enterocytes - Digestion" 8 Microtubules Nucleoli "HPA046755: AB_10963433, HPA058759: AB_2683809" "unprognostic (1.05e-2)" "unprognostic (6.01e-2)" "unprognostic (1.89e-1)" "unprognostic (2.44e-1)" "unprognostic (1.91e-1)" "unprognostic (3.55e-1)" "unprognostic (1.05e-3)" "unprognostic (9.17e-3)" "unprognostic (2.02e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.16e-3)" "unprognostic (3.13e-1)" "prognostic favorable (1.18e-5)" "unprognostic (1.89e-1)" "unprognostic (1.02e-1)" "unprognostic (7.21e-3)" "unprognostic (2.38e-1)" NUDT16 FLJ31265 ENSG00000198585 "Nudix hydrolase 16" Q96DE0 3 131381671-131388830 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 178.1;monocytes: 185.8;Proximal enterocytes: 315.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 41.7;eosinophil: 47.1;intermediate monocyte: 54.6;myeloid DC: 32.5;neutrophil: 34.1;non-classical monocyte: 63.7" "Group enriched" "Detected in all" 4 "dendritic cells: 32.5;granulocytes: 47.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060452, HPA062492" Uncertain Supported Nucleoplasm,Nucleoli NA NA 38000 "Cluster 25: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Proximal enterocytes - Digestion" "Nucleoplasm, Nucleoli" "HPA060452: AB_2684279, HPA062492: AB_2684781" "unprognostic (4.85e-3)" "prognostic favorable (9.39e-5)" "unprognostic (3.19e-3)" "unprognostic (9.21e-2)" "unprognostic (2.49e-1)" "unprognostic (1.22e-2)" "unprognostic (9.96e-2)" "unprognostic (1.15e-1)" "unprognostic (5.16e-2)" "unprognostic (1.94e-1)" "unprognostic (1.77e-1)" "unprognostic (5.88e-2)" "prognostic favorable (1.05e-7)" "unprognostic (3.29e-1)" "unprognostic (1.62e-1)" "unprognostic (2.00e-2)" "unprognostic (9.44e-2)" NUDT18 "FLJ22494, MTH3" ENSG00000275074 "Nudix hydrolase 18" Q6ZVK8 8 22106874-22109419 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028581, HPA030125" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 15 Nucleoplasm "Golgi apparatus" "HPA028581: AB_10601381, HPA030125: AB_2673324" "unprognostic (9.90e-3)" "prognostic favorable (1.43e-4)" "unprognostic (4.88e-3)" "prognostic favorable (2.49e-6)" "unprognostic (1.29e-2)" "unprognostic (6.82e-3)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (5.30e-2)" "unprognostic (1.67e-1)" "prognostic favorable (2.47e-4)" "unprognostic (1.43e-1)" "prognostic favorable (8.30e-4)" "unprognostic (3.59e-3)" "unprognostic (1.05e-1)" "unprognostic (6.84e-2)" "unprognostic (2.32e-1)" NUDT8 FLJ41567 ENSG00000167799 "Nudix hydrolase 8" Q8WV74 11 67627938-67629937 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 76.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 224.6;Proximal enterocytes: 157.8;Proximal tubular cells: 220.1;Squamous epithelial cells: 145.0;Suprabasal keratinocytes: 177.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "HPA041252, HPA041466" Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" Nucleoli Cytosol "HPA041252: AB_10794551, HPA041466: AB_10793967" "unprognostic (8.31e-2)" "unprognostic (7.26e-3)" "unprognostic (7.31e-2)" "unprognostic (7.32e-2)" "unprognostic (2.87e-1)" "unprognostic (2.36e-3)" "unprognostic (2.69e-1)" "unprognostic (4.12e-2)" "unprognostic (8.28e-2)" "unprognostic (2.69e-2)" "unprognostic (3.11e-2)" "unprognostic (2.74e-1)" "prognostic favorable (3.70e-4)" "unprognostic (4.70e-2)" "unprognostic (2.29e-1)" "unprognostic (3.50e-1)" "unprognostic (2.19e-1)" OAT HOGA ENSG00000065154 "Ornithine aminotransferase" P04181 10 124397303-124418976 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 760.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 1114.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033576, HPA040098, HPA064742" Enhanced Supported Nucleoplasm,Mitochondria NA NA 12000 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" 1 Mitochondria Nucleoplasm "CAB033576: AB_2298892, HPA040098: AB_10793955, HPA064742: AB_2685343" "unprognostic (1.61e-2)" "unprognostic (1.70e-2)" "unprognostic (9.96e-2)" "unprognostic (1.02e-2)" "unprognostic (1.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.03e-1)" "unprognostic (4.43e-3)" "unprognostic (1.65e-1)" "unprognostic (2.37e-2)" "unprognostic (2.45e-1)" "unprognostic (7.62e-2)" "unprognostic (1.70e-2)" "unprognostic (2.21e-1)" "unprognostic (2.19e-1)" "unprognostic (2.72e-2)" "unprognostic (2.00e-2)" OCEL1 FLJ22709 ENSG00000099330 "Occludin/ELL domain containing 1" Q9H607 19 17226213-17229219 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 73.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 108.8;Proximal enterocytes: 129.4;Proximal tubular cells: 134.0;Syncytiotrophoblasts: 120.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042070, HPA043223" Uncertain Approved "Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" "Golgi apparatus" "HPA042070: AB_2677830, HPA043223: " "unprognostic (6.34e-2)" "unprognostic (6.28e-2)" "unprognostic (3.13e-1)" "unprognostic (3.00e-3)" "unprognostic (6.40e-2)" "unprognostic (2.06e-2)" "unprognostic (4.33e-3)" "unprognostic (2.02e-1)" "unprognostic (1.16e-1)" "unprognostic (1.67e-1)" "unprognostic (7.73e-2)" "unprognostic (4.64e-1)" "unprognostic (1.34e-1)" "unprognostic (2.52e-1)" "unprognostic (2.88e-1)" "unprognostic (9.19e-2)" "unprognostic (1.18e-3)" OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 149.6" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 640.1;Proximal enterocytes: 708.4;Proximal tubular cells: 1226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA040979: AB_10795497, HPA041090: AB_10796236" "unprognostic (4.29e-1)" "unprognostic (2.69e-1)" "unprognostic (3.76e-2)" "prognostic favorable (7.37e-4)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (9.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-1)" "prognostic favorable (6.56e-4)" "prognostic unfavorable (6.89e-4)" "unprognostic (1.38e-1)" "prognostic favorable (2.67e-5)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (8.24e-3)" "prognostic favorable (2.34e-4)" OGG1 "HMMH, HOGG1, MUTM, OGH1" ENSG00000114026 "8-oxoguanine DNA glycosylase" O15527 3 9749944-9788219 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 46.9;Proximal tubular cells: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027514, CAB047301" Approved Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 47: Spleen - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Nucleoplasm "CAB047301: , HPA027514: AB_10602189" "unprognostic (6.95e-2)" "unprognostic (7.82e-3)" "unprognostic (7.19e-2)" "unprognostic (1.24e-3)" "unprognostic (9.69e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (5.77e-5)" "unprognostic (7.83e-2)" "unprognostic (2.45e-2)" "unprognostic (3.43e-3)" "unprognostic (9.66e-3)" "unprognostic (4.23e-2)" "prognostic favorable (2.65e-4)" "unprognostic (2.06e-2)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.59e-1)" OSBPL7 "MGC71150, ORP7" ENSG00000006025 "Oxysterol binding protein like 7" Q9BZF2 17 47807372-47821834 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 36.9;Gastric mucus-secreting cells: 109.1;Intestinal goblet cells: 25.6;Paneth cells: 26.3;Proximal enterocytes: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036076, HPA053083, HPA073967" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 46: Gastric mucus-secreting cells - Digestion" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036076: AB_10601042, HPA053083: AB_2682038, HPA073967: " "unprognostic (3.88e-2)" "unprognostic (2.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.55e-3)" "unprognostic (2.05e-3)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (3.33e-1)" "unprognostic (1.97e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.17e-1)" "unprognostic (1.36e-1)" "unprognostic (3.08e-1)" "prognostic favorable (1.19e-5)" P2RX4 P2X4 ENSG00000135124 "Purinergic receptor P2X 4" Q99571 12 121210065-121234106 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 135.4;Hofbauer cells: 118.5;Intestinal goblet cells: 100.8;Proximal enterocytes: 94.8;Syncytiotrophoblasts: 157.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039494 Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 24: Cytotrophoblasts - Mitochondria" 6 "HPA039494: AB_10969132" "unprognostic (4.02e-3)" "unprognostic (1.06e-1)" "unprognostic (5.43e-2)" "prognostic favorable (6.30e-10)" "unprognostic (2.98e-2)" "unprognostic (2.52e-1)" "unprognostic (2.06e-3)" "unprognostic (1.68e-1)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (7.71e-2)" "unprognostic (2.18e-1)" "unprognostic (1.81e-2)" "unprognostic (1.13e-1)" "unprognostic (6.06e-2)" "unprognostic (1.42e-2)" "unprognostic (4.76e-3)" P2RY2 P2U ENSG00000175591 "Purinergic receptor P2Y2" P41231 11 73218281-73242427 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 28.9;skeletal muscle: 48.4;tongue: 29.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.3;Proximal enterocytes: 15.0;Squamous epithelial cells: 15.4;Suprabasal keratinocytes: 13.7;Syncytiotrophoblasts: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 57.7" "Group enriched" "Detected in many" 12 "granulocytes: 57.7;monocytes: 20.2" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB022642 Uncertain Uncertain Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 Cytosol "CAB022642: " "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (6.50e-4)" "unprognostic (2.04e-2)" "unprognostic (4.66e-3)" "unprognostic (8.93e-2)" "unprognostic (2.87e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (9.69e-2)" "unprognostic (4.92e-4)" "unprognostic (1.34e-1)" "unprognostic (2.82e-1)" "unprognostic (1.05e-1)" "unprognostic (8.57e-3)" PAFAH2 HSD-PLA2 ENSG00000158006 "Platelet activating factor acetylhydrolase 2" Q99487 1 25959767-25998117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 47.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 44.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018157 Approved NA Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 49: HMC-1 - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" "HPA018157: AB_1854928" "unprognostic (9.89e-2)" "unprognostic (2.60e-1)" "unprognostic (3.63e-3)" "prognostic favorable (3.28e-6)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (4.46e-2)" "unprognostic (2.62e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.15e-2)" "unprognostic (8.17e-2)" "unprognostic (1.59e-2)" "unprognostic (7.27e-2)" PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 131.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 317.9;Distal enterocytes: 182.0;monocytes: 464.6;Proximal enterocytes: 167.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Heart muscle - Endothelial cells, Liver - Hepatocytes, Prostate - Fibroblasts, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 16000 "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Liver - Plasma proteins" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 29: Monocytes - Innate immune response" 3 Mitochondria "HPA071224: AB_2686366, HPA075267: " "unprognostic (3.98e-3)" "unprognostic (7.06e-2)" "unprognostic (4.95e-3)" "unprognostic (1.02e-1)" "unprognostic (2.67e-1)" "unprognostic (1.61e-2)" "unprognostic (4.96e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (3.50e-2)" "prognostic favorable (6.58e-4)" "unprognostic (1.14e-1)" "unprognostic (4.90e-2)" "unprognostic (6.72e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.21e-5)" "unprognostic (3.46e-3)" PAQR8 "C6orf33, LMPB1, MPRB" ENSG00000170915 "Progestin and adipoQ receptor family member 8" Q8TEZ7 6 52361421-52407777 "Predicted membrane proteins, Transporters" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 141.3" "Cell type enhanced" "Detected in many" "Astrocytes: 159.8;Distal enterocytes: 128.9;Microglial cells: 70.7;Oligodendrocytes: 277.5;Paneth cells: 81.2;Proximal enterocytes: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 31.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064625 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 3 "Plasma membrane" "Golgi apparatus" "HPA064625: AB_2685304" "prognostic favorable (4.61e-4)" "unprognostic (7.39e-3)" "unprognostic (2.77e-3)" "unprognostic (8.23e-2)" "unprognostic (4.33e-1)" "unprognostic (4.08e-3)" "unprognostic (2.66e-2)" "unprognostic (5.67e-2)" "unprognostic (6.37e-2)" "unprognostic (4.30e-3)" "unprognostic (2.10e-1)" "unprognostic (5.55e-2)" "unprognostic (8.82e-3)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (3.14e-2)" "prognostic favorable (6.40e-4)" PARP3 "ADPRT3, ADPRTL3, ARTD3, hPARP-3, IRT1, pADPRT-3" ENSG00000041880 "Poly(ADP-ribose) polymerase family member 3" Q9Y6F1 3 51942345-51948867 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 33.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020984, HPA067657" Supported Supported "Nucleoplasm,Nuclear bodies" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 22: Proximal enterocytes - Digestion" 3 "Nucleoplasm, Nuclear bodies" "HPA020984: , HPA067657: AB_2685881" "prognostic favorable (6.39e-5)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (2.85e-2)" "unprognostic (7.31e-2)" "unprognostic (1.56e-1)" "unprognostic (4.13e-1)" "unprognostic (3.53e-2)" "unprognostic (2.26e-1)" "unprognostic (2.01e-1)" "unprognostic (7.44e-3)" "unprognostic (4.30e-1)" "prognostic favorable (1.25e-8)" "unprognostic (5.63e-2)" "unprognostic (1.77e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-3)" PCK1 PEPCK-C ENSG00000124253 "Phosphoenolpyruvate carboxykinase 1" P35558 20 57561080-57568121 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Gluconeogenesis "Decarboxylase, Kinase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 416.9;liver: 664.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 790.0;Distal tubular cells: 387.3;Hepatocytes: 1050.8;Proximal enterocytes: 1934.7;Proximal tubular cells: 2045.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 99.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "colorectal cancer: 6.2;Gastric cancer: 3.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Adipocytes (Skin)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006277, HPA006507, CAB017027" Approved NA NA 840000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "CAB017027: , HPA006277: AB_1079579, HPA006507: AB_1079578" "unprognostic (3.50e-2)" "unprognostic (5.60e-2)" "unprognostic (4.60e-2)" "unprognostic (8.62e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.84e-1)" "unprognostic (2.37e-1)" "unprognostic (1.64e-1)" "prognostic favorable (1.47e-5)" "unprognostic (1.03e-1)" "unprognostic (6.40e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-1)" PCSK5 "PC5, PC6, SPC6" ENSG00000099139 "Proprotein convertase subtilisin/kexin type 5" Q92824 9 75890644-76362975 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Pregnancy "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 25.2" "Cell type enhanced" "Detected in many" "Astrocytes: 179.9;Inhibitory neurons: 78.0;Oligodendrocyte precursor cells: 140.1;Proximal enterocytes: 149.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 4.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031072 Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA 290000 "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 10 "Golgi apparatus" "HPA031072: AB_10602190" "unprognostic (3.28e-2)" "unprognostic (1.44e-1)" "unprognostic (4.13e-4)" "unprognostic (4.08e-2)" "unprognostic (7.43e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-3)" "unprognostic (9.39e-2)" "unprognostic (1.15e-1)" "unprognostic (5.92e-2)" "unprognostic (2.81e-2)" "unprognostic (6.80e-2)" "prognostic unfavorable (9.61e-5)" "unprognostic (2.99e-1)" "unprognostic (3.21e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-5)" PDCD6 "ALG-2, PEF1B" ENSG00000249915 "Programmed cell death 6" O75340 5 271621-314974 "Plasma proteins, Predicted intracellular proteins, Transporters" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 95.3;Proximal enterocytes: 77.0;Undifferentiated cells: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047221 Supported Nucleoplasm,Cytosol No No 1800000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 80: Non-specific - Endocytosis" "Cluster 27: Non-specific - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 12 Cytosol Nucleoplasm "HPA047221: " "unprognostic (1.32e-1)" "unprognostic (5.01e-2)" "unprognostic (2.10e-2)" "unprognostic (4.41e-3)" "unprognostic (4.94e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (5.47e-5)" "unprognostic (1.56e-1)" "unprognostic (1.27e-2)" "unprognostic (4.37e-2)" "unprognostic (1.14e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (5.16e-6)" "unprognostic (7.97e-2)" "unprognostic (1.48e-1)" "unprognostic (2.67e-1)" "prognostic favorable (2.19e-4)" PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653621-42775509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 72.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 75.7;Oocytes: 197.8;Paneth cells: 72.0;Prostatic glandular cells: 108.8;Proximal enterocytes: 213.7" "Cancer enriched" "Detected in all" 5 "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "prostate cancer: 40.8" "Adipose subcutaneous - Endothelial cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011380, HPA011978" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 45: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 14 Cytosol "Nucleoplasm, Plasma membrane" "HPA011380: AB_1855132, HPA011978: " "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 208.6;tongue: 273.6" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 115.7;Proximal tubular cells: 111.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "Nucleoplasm, Mitochondria" "HPA008287: AB_1079589" "unprognostic (2.74e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.16e-1)" "unprognostic (2.43e-3)" "unprognostic (1.22e-1)" "unprognostic (9.63e-3)" "unprognostic (9.80e-3)" "unprognostic (8.39e-3)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "prognostic favorable (9.59e-5)" "unprognostic (3.81e-1)" "unprognostic (2.54e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" PDLIM1 "CLIM1, CLP-36, CLP36, hCLIM1" ENSG00000107438 "PDZ and LIM domain 1" O00151 10 95237572-95291012 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 651.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 703.7;Paneth cells: 692.8;Proximal enterocytes: 1075.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 190.2;memory B-cell: 224.6;naive B-cell: 213.9" "Group enriched" "Detected in all" 7 "B-cells: 224.6;granulocytes: 190.2" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017010, CAB072838, CAB072840" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 93000000 "Cluster 22: Eosinophils - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 57: Platelets - Hemostasis" 2 "Actin filaments" "Plasma membrane, Cell Junctions" "CAB072838: , CAB072840: , HPA017010: AB_1855147" "unprognostic (1.61e-1)" "unprognostic (2.87e-2)" "unprognostic (2.58e-2)" "prognostic favorable (1.14e-5)" "unprognostic (3.18e-2)" "unprognostic (7.54e-2)" "unprognostic (2.07e-1)" "unprognostic (8.99e-2)" "unprognostic (2.26e-1)" "unprognostic (2.82e-3)" "unprognostic (5.77e-2)" "unprognostic (6.56e-2)" "unprognostic (1.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-1)" "unprognostic (4.21e-3)" "unprognostic (1.11e-1)" PDSS1 "COQ1, COQ1A, TPRT, TPT" ENSG00000148459 "Decaprenyl diphosphate synthase subunit 1" Q5T2R2 10 26697701-26746798 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Lipid metabolism, Ubiquinone biosynthesis" Transferase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 13.4" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 31.1;Proximal enterocytes: 28.9;Undifferentiated cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038032, HPA042741" Uncertain Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 45: Intestine - Digestion" "Cluster 2: Neurons - Nucleosome" "Cluster 52: Non-specific - Mitochondria" "Cluster 65: Neurons - Synaptic function" Cytosol "HPA038032: AB_10670650, HPA042741: AB_2678139" "unprognostic (1.41e-2)" "unprognostic (3.92e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (1.66e-4)" "unprognostic (6.79e-3)" "unprognostic (5.43e-2)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.47e-2)" "unprognostic (9.43e-2)" "unprognostic (2.33e-2)" "unprognostic (2.20e-1)" "unprognostic (4.11e-2)" "unprognostic (2.99e-3)" "unprognostic (2.93e-3)" "unprognostic (8.85e-2)" "unprognostic (9.83e-2)" "unprognostic (6.36e-2)" PEBP1 "HCNP, PBP, PEBP, RKIP" ENSG00000089220 "Phosphatidylethanolamine binding protein 1" P30086 12 118136124-118145584 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2019.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 2259.0;Hepatocytes: 2612.9;Proximal enterocytes: 2320.9;Proximal tubular cells: 3732.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "HPA008819, CAB009906, CAB013493, HPA063904, CAB080063" Enhanced Approved "Plasma membrane,Cytosol" NA NA 51000000 "Cluster 18: Non-specific - Translation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 5 "Plasma membrane, Cytosol" "CAB009906: AB_2163173, CAB013493: AB_2533305, CAB080063: , HPA008819: AB_1855173, HPA063904: AB_2732708" "unprognostic (4.57e-1)" "unprognostic (1.03e-3)" "unprognostic (3.28e-2)" "unprognostic (3.39e-3)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" "unprognostic (1.24e-2)" "unprognostic (7.35e-3)" "unprognostic (5.67e-2)" "unprognostic (3.55e-2)" "prognostic favorable (1.52e-4)" "unprognostic (1.63e-1)" "prognostic favorable (2.15e-13)" "unprognostic (2.17e-1)" "unprognostic (7.72e-2)" "unprognostic (7.96e-2)" "unprognostic (8.80e-2)" PEX11G PEX11gamma ENSG00000104883 "Peroxisomal biogenesis factor 11 gamma" Q96HA9 19 7476875-7497449 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 25.8;testis: 28.2" "Cell type enhanced" "Detected in many" "Early spermatids: 93.7;Hepatocytes: 43.7;Late spermatids: 72.5;Proximal enterocytes: 36.9;Proximal tubular cells: 37.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA069817 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 5 "HPA069817: AB_2686207" "unprognostic (2.26e-2)" "unprognostic (6.44e-2)" "unprognostic (1.47e-2)" "prognostic favorable (3.60e-4)" "unprognostic (1.01e-1)" "unprognostic (4.09e-3)" "prognostic favorable (3.27e-4)" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "unprognostic (3.16e-1)" "unprognostic (2.32e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.83e-9)" "unprognostic (1.21e-3)" "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (1.19e-2)" PEX26 FLJ20695 ENSG00000215193 "Peroxisomal biogenesis factor 26" Q7Z412 22 18077923-18105396 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 107.9;Proximal enterocytes: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB070429 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Small intestine - Absorption" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 5: Enterocytes - Absorption" 28 "CAB070429: AB_11154363" "unprognostic (2.25e-1)" "unprognostic (5.75e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.77e-3)" "unprognostic (5.46e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.10e-4)" "unprognostic (1.59e-2)" "unprognostic (5.34e-2)" "unprognostic (8.19e-2)" "unprognostic (1.88e-2)" "unprognostic (1.96e-1)" "prognostic favorable (1.38e-4)" "unprognostic (3.17e-3)" "unprognostic (4.53e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" PFKFB4 ENSG00000114268 "6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4" Q16877 3 48517684-48562015 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Kinase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 23.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 44.9;Intestinal goblet cells: 17.5;Proximal enterocytes: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 12.6;eosinophil: 22.0;intermediate monocyte: 13.8;neutrophil: 40.6;non-classical monocyte: 25.2" "Group enriched" "Detected in many" 6 "granulocytes: 40.6;monocytes: 25.2" "Cancer enhanced" "Detected in all" "skin cancer: 60.4" "Lung - Neutrophil_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047719, HPA066058" Uncertain Approved Nucleoli NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 39: Retina & Testis - Cilium" "Cluster 6: Non-specific - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 4 Nucleoli "HPA047719: AB_2680129, HPA066058: AB_2685606" "unprognostic (7.60e-2)" "prognostic unfavorable (3.04e-4)" "unprognostic (1.01e-1)" "unprognostic (1.19e-1)" "unprognostic (3.90e-3)" "unprognostic (7.96e-2)" "unprognostic (1.72e-6)" "unprognostic (1.65e-1)" "unprognostic (3.75e-2)" "unprognostic (6.78e-2)" "unprognostic (3.78e-2)" "unprognostic (7.13e-2)" "prognostic unfavorable (3.91e-8)" "unprognostic (2.04e-1)" "unprognostic (6.28e-2)" "unprognostic (2.43e-3)" "unprognostic (3.35e-2)" PFKL ENSG00000141959 "Phosphofructokinase, liver type" P17858 21 44300051-44327376 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 249.1;Proximal enterocytes: 329.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030047 Approved Uncertain Nucleoli,Mitochondria NA NA 1100000 "Cluster 33: Non-specific - ATP binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 4 "Nucleoli, Mitochondria" "HPA030047: AB_10602815" "unprognostic (6.21e-3)" "unprognostic (2.93e-1)" "unprognostic (4.46e-2)" "unprognostic (1.23e-2)" "unprognostic (1.87e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "unprognostic (6.98e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (4.41e-4)" "unprognostic (5.69e-2)" "unprognostic (5.40e-2)" "unprognostic (1.55e-1)" "unprognostic (4.99e-1)" "unprognostic (2.49e-1)" "unprognostic (8.06e-2)" "unprognostic (3.01e-2)" PGPEP1 "Pcp, PGP, PGP-I, PGPI" ENSG00000130517 "Pyroglutamyl-peptidase I" Q9NXJ5 19 18340598-18369950 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 69.2;Proximal enterocytes: 73.7;Proximal tubular cells: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 28.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 28.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035368, HPA055277" Approved Approved "Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 44: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 38: Proximal tubular cells - Transmembrane transport" "Golgi apparatus" "HPA035368: AB_10601388, HPA055277: AB_2682770" "unprognostic (9.52e-3)" "unprognostic (1.37e-2)" "unprognostic (6.95e-2)" "unprognostic (5.74e-3)" "unprognostic (5.29e-2)" "unprognostic (6.60e-2)" "unprognostic (1.96e-2)" "unprognostic (2.11e-3)" "prognostic favorable (6.80e-4)" "unprognostic (2.79e-2)" "prognostic favorable (1.71e-4)" "unprognostic (4.81e-3)" "prognostic favorable (3.71e-8)" "unprognostic (1.12e-2)" "unprognostic (1.66e-1)" "unprognostic (1.51e-1)" "unprognostic (1.20e-3)" PHETA1 "FAM109A, FLJ32356, IPIP27A, SES1" ENSG00000198324 "PH domain containing endocytic trafficking adaptor 1" Q8N4B1 12 111360651-111369121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 41.8;Proximal enterocytes: 50.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 1 "unprognostic (2.26e-1)" "unprognostic (6.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.05e-1)" "unprognostic (6.02e-2)" "unprognostic (1.15e-3)" "unprognostic (6.18e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (5.51e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.95e-1)" "unprognostic (1.31e-1)" "unprognostic (4.90e-2)" "unprognostic (2.80e-3)" PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 21.3;retina: 31.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.4;Distal enterocytes: 52.3;Excitatory neurons: 67.2;Proximal enterocytes: 63.3;Rod photoreceptor cells: 77.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040761, HPA041837, HPA048598" Approved Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No "Cluster 39: Retina & Testis - Cilium" "Cluster 1: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 5: Enterocytes - Absorption" 10 Cytosol "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA040761: , HPA041837: , HPA048598: AB_2680459" "unprognostic (5.67e-2)" "unprognostic (2.00e-1)" "unprognostic (2.29e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.22e-1)" "unprognostic (3.43e-1)" "unprognostic (1.97e-4)" "unprognostic (3.08e-2)" "unprognostic (8.85e-3)" "unprognostic (6.41e-2)" "unprognostic (4.92e-2)" "unprognostic (8.46e-3)" "unprognostic (8.27e-2)" PIGR ENSG00000162896 "Polymeric immunoglobulin receptor" P01833 1 206928522-206946466 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2560.5;salivary gland: 1591.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 9136.7;Enteroendocrine cells: 1484.9;Intestinal goblet cells: 1895.6;Paneth cells: 2797.4;Proximal enterocytes: 1597.7;Serous glandular cells: 1581.6;Undifferentiated cells: 3247.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 731.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bile duct cancer: 29.7;colorectal cancer: 30.9;Gastric cancer: 55.5" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA006154, CAB009454, HPA012012" Enhanced "Secreted to digestive system" "No annotated function" NA NA 1300000000 "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "CAB009454: AB_2164819, HPA006154: AB_1855370, HPA012012: AB_1855371" "prognostic favorable (1.22e-5)" "unprognostic (7.42e-2)" "unprognostic (4.78e-3)" "prognostic favorable (2.57e-4)" "unprognostic (2.31e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (3.07e-2)" "unprognostic (6.45e-2)" "unprognostic (1.19e-1)" "unprognostic (5.23e-2)" "unprognostic (2.13e-1)" "prognostic favorable (5.08e-5)" "unprognostic (1.83e-1)" "unprognostic (1.41e-1)" "unprognostic (6.92e-3)" "unprognostic (3.39e-2)" PIK3R2 "p85, P85B" ENSG00000105647 "Phosphoinositide-3-kinase regulatory subunit 2" O00459 19 18153163-18170532 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Stress response, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 13.1;Undifferentiated cells: 14.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069291 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 16: Intestinal goblet cells - Mucin production" 21 "HPA069291: AB_2686109" "unprognostic (2.50e-1)" "unprognostic (1.90e-3)" "unprognostic (1.68e-2)" "unprognostic (1.87e-1)" "unprognostic (2.00e-2)" "unprognostic (9.65e-3)" "unprognostic (1.69e-3)" "unprognostic (2.36e-3)" "unprognostic (9.24e-2)" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (3.36e-1)" "unprognostic (1.69e-2)" "unprognostic (2.02e-1)" "unprognostic (6.35e-3)" "unprognostic (8.63e-2)" "unprognostic (2.00e-2)" PITX2 "ARP1, Brx1, IGDS, IHG2, IRID2, Otlx2, RGS, RIEG, RIEG1, RS" ENSG00000164093 "Paired like homeodomain 2" Q99697 4 110617423-110642123 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 40.6;skeletal muscle: 41.6;tongue: 27.0;urinary bladder: 28.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 28.8;Cardiomyocytes: 18.5;Paneth cells: 27.1;Proximal enterocytes: 39.6;Skeletal myocytes: 70.3;Smooth muscle cells: 38.2;Suprabasal keratinocytes: 36.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "hypothalamus: 29.9;thalamus: 10.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 23 "hypothalamus: 8.6;midbrain: 2.3" "HPA050074, HPA062728" Enhanced Nucleoplasm NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 1 Nucleoplasm "HPA050074: AB_2681005, HPA062728: AB_2684851" "unprognostic (1.08e-1)" "unprognostic (1.23e-2)" "unprognostic (9.29e-2)" "unprognostic (9.24e-2)" "unprognostic (1.68e-1)" "unprognostic (1.14e-2)" "unprognostic (9.61e-4)" "unprognostic (3.22e-2)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.16e-1)" "unprognostic (2.77e-1)" "unprognostic (1.11e-15)" "unprognostic (6.97e-3)" "unprognostic (1.43e-1)" "unprognostic (5.98e-2)" "unprognostic (9.91e-2)" PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 286.1;skin 1: 215.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 144.7;Distal enterocytes: 292.7;Extravillous trophoblasts: 188.1;Proximal enterocytes: 181.7;Suprabasal keratinocytes: 353.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Endothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 59: Suprabasal keratinocytes - Cornification" 3 "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" PLAAT4 "HRASLS4, PLAAT-4, RARRES3, RIG1, TIG3" ENSG00000133321 "Phospholipase A and acyltransferase 4" Q9UL19 11 63536808-63546462 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 377.2;Proximal enterocytes: 545.4;Proximal tubular cells: 1123.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "pancreatic cancer: 137.3" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 2 "prognostic favorable (1.35e-5)" "prognostic favorable (4.00e-4)" "unprognostic (4.12e-2)" "unprognostic (1.37e-1)" "unprognostic (3.30e-1)" "unprognostic (2.45e-2)" "unprognostic (2.11e-1)" "unprognostic (6.91e-2)" "unprognostic (1.78e-1)" "unprognostic (2.92e-2)" "prognostic unfavorable (6.26e-6)" "unprognostic (8.50e-2)" "unprognostic (1.59e-1)" "unprognostic (3.42e-1)" "unprognostic (2.11e-1)" "unprognostic (9.36e-3)" "unprognostic (2.64e-1)" PLCB3 ENSG00000149782 "Phospholipase C beta 3" Q01970 11 64251530-64269150 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 110.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 46.9;Proximal enterocytes: 139.4;Undifferentiated cells: 53.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009257, HPA039279, HPA043907" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 210000 "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" 2 Nucleoplasm "Golgi apparatus" "CAB009257: AB_654079, HPA039279: AB_2676425, HPA043907: AB_2678726" "unprognostic (1.30e-1)" "unprognostic (1.21e-2)" "unprognostic (2.86e-1)" "unprognostic (2.35e-1)" "unprognostic (9.35e-2)" "unprognostic (6.23e-3)" "prognostic unfavorable (1.39e-4)" "unprognostic (2.44e-2)" "unprognostic (6.61e-2)" "unprognostic (1.26e-1)" "unprognostic (8.07e-3)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.31e-5)" "unprognostic (5.04e-3)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (3.88e-2)" PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 49.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 90.2;Basal respiratory cells: 60.5;Intestinal goblet cells: 57.5;Langerhans cells: 66.3;Proximal enterocytes: 49.1;Suprabasal keratinocytes: 58.3;Undifferentiated cells: 54.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Leydig cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 53: Non-specific - Glycosylation" "Cluster 15: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 45: Non-specific - Mixed function" Vesicles Cytosol "HPA001208: AB_1079631" "unprognostic (4.41e-3)" "unprognostic (3.77e-1)" "unprognostic (1.15e-1)" "unprognostic (6.23e-2)" "unprognostic (6.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.97e-1)" "unprognostic (9.21e-3)" "prognostic unfavorable (8.26e-5)" "unprognostic (1.06e-1)" "unprognostic (3.09e-3)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (8.98e-2)" "unprognostic (4.59e-2)" PLEKHG6 "FLJ10665, MYOGEF" ENSG00000008323 "Pleckstrin homology and RhoGEF domain containing G6" Q3KR16 12 6310436-6328506 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.0;intestine: 38.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 93.2;Extravillous trophoblasts: 61.0;Paneth cells: 45.1;Proximal enterocytes: 60.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041459, HPA058230" Uncertain Supported "Cell Junctions,Centrosome" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 19: Astrocytes - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 1 "Cell Junctions" Centrosome "HPA041459: AB_10794518, HPA058230: AB_2683645" "unprognostic (1.67e-1)" "unprognostic (9.93e-3)" "unprognostic (1.44e-1)" "unprognostic (8.03e-3)" "unprognostic (5.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.20e-2)" "unprognostic (1.22e-1)" "unprognostic (3.13e-1)" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (6.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (4.18e-2)" "unprognostic (5.73e-2)" PLEKHJ1 FLJ10297 ENSG00000104886 "Pleckstrin homology domain containing J1" Q9NW61 19 2230084-2237704 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 351.1;Proximal enterocytes: 350.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048989 Approved Approved Mitochondria No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 5 Mitochondria "HPA048989: AB_2680590" "unprognostic (5.11e-1)" "unprognostic (4.84e-3)" "unprognostic (2.33e-1)" "unprognostic (9.82e-2)" "unprognostic (1.38e-1)" "unprognostic (7.83e-2)" "unprognostic (2.03e-3)" "unprognostic (2.89e-3)" "unprognostic (1.51e-1)" "unprognostic (1.71e-1)" "unprognostic (9.03e-3)" "unprognostic (3.49e-2)" "prognostic favorable (1.10e-5)" "prognostic favorable (6.99e-4)" "unprognostic (5.67e-2)" "unprognostic (1.15e-1)" "unprognostic (6.26e-3)" PLGRKT "AD025, C9orf46, FLJ14688, MDS030, Plg-RKT" ENSG00000107020 "Plasminogen receptor with a C-terminal lysine" Q9HBL7 9 5357971-5437925 "Predicted intracellular proteins" "Chemotaxis, Inflammatory response, Plasminogen activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 184.7;Proximal enterocytes: 221.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 245.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008214, HPA011144" Supported Uncertain Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 5: Enterocytes - Absorption" Mitochondria "HPA008214: AB_1078363, HPA011144: AB_1078364" "prognostic favorable (5.56e-4)" "unprognostic (5.31e-2)" "unprognostic (2.96e-2)" "unprognostic (9.67e-2)" "unprognostic (1.05e-1)" "unprognostic (2.12e-2)" "unprognostic (1.72e-1)" "unprognostic (1.89e-2)" "unprognostic (3.85e-2)" "unprognostic (5.45e-3)" "unprognostic (2.19e-2)" "unprognostic (1.84e-1)" "prognostic favorable (5.09e-5)" "unprognostic (1.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" PLIN3 "M6PRBP1, PP17, TIP47" ENSG00000105355 "Perilipin 3" O60664 19 4838341-4867694 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 280.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006427, HPA066538" Uncertain Supported "Lipid droplets,Cytosol" NA Yes 11000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 5: Enterocytes - Absorption" 22 "Lipid droplets" Cytosol "HPA006427: AB_1079289, HPA066538: AB_2685687" "unprognostic (1.18e-1)" "unprognostic (4.86e-2)" "unprognostic (1.55e-2)" "prognostic favorable (2.62e-4)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.27e-5)" "prognostic unfavorable (7.67e-6)" "unprognostic (2.27e-1)" "unprognostic (1.28e-1)" "unprognostic (4.34e-2)" "unprognostic (8.24e-2)" "prognostic unfavorable (9.15e-7)" "unprognostic (2.62e-1)" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (2.39e-2)" PLLP "PMLP, TM4SF11" ENSG00000102934 Plasmolipin Q9Y342 16 57248547-57284672 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 200.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 163.1;Cholangiocytes: 166.0;Glandular and luminal cells: 144.8;Oligodendrocyte precursor cells: 131.6;Oligodendrocytes: 180.0;Proximal enterocytes: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "naive CD4 T-cell: 14.5;naive CD8 T-cell: 5.7" "Lineage enriched" "Detected in many" 8 "T-cells: 14.5" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 47.5" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041862 Enhanced NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 18: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Glandular & Luminal cells - Unknown function" 33 "HPA041862: AB_2677712" "unprognostic (7.96e-2)" "unprognostic (2.07e-3)" "unprognostic (3.86e-2)" "prognostic favorable (2.80e-4)" "unprognostic (3.19e-1)" "unprognostic (1.42e-1)" "unprognostic (9.56e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (5.64e-2)" "unprognostic (6.99e-3)" "unprognostic (2.83e-2)" "prognostic favorable (6.21e-9)" "unprognostic (2.06e-2)" "unprognostic (9.06e-3)" "unprognostic (3.86e-1)" "unprognostic (3.32e-2)" PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 102.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 221.3;Ciliated cells: 211.6;Club cells: 236.1;Ductal cells: 340.4;Ionocytes: 251.4;Proximal enterocytes: 205.6;Rod photoreceptor cells: 242.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.3;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 40 "T-cells: 6.6" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576900-41589871 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 154.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 5: Enterocytes - Absorption" 2 Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favorable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favorable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favorable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" PMP22 "CMT1A, GAS3, HMSNIA, HNPP, Sp110" ENSG00000109099 "Peripheral myelin protein 22" Q01453 17 15229773-15272292 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes, Charcot-Marie-Tooth disease, Deafness, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 347.6;Hofbauer cells: 498.1;Leydig cells: 336.5;Melanocytes: 566.9;Proximal enterocytes: 708.2;Schwann cells: 1057.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 32.3;eosinophil: 43.1;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 22 "dendritic cells: 23.9;granulocytes: 43.1" "Group enriched" "Detected in many" 5 "Adrenocortical cancer: 276.5;Brain cancer: 135.3;Rhabdoid: 121.6;skin cancer: 209.0;testis cancer: 307.6" "Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 1023.1" "Intracellular and membrane" "No annotated function" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 34: Non-specific - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 52 "unprognostic (3.00e-1)" "unprognostic (1.65e-1)" "unprognostic (2.21e-1)" "unprognostic (4.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.28e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-1)" "unprognostic (4.33e-2)" "unprognostic (7.70e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.83e-2)" "unprognostic (5.45e-2)" "unprognostic (2.88e-1)" "unprognostic (1.08e-2)" POF1B "FLJ22792, POF" ENSG00000124429 "POF1B actin binding protein" Q8WVV4 X 85277396-85379717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 52.5;skin 1: 120.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 130.2;Gastric mucus-secreting cells: 45.4;Intestinal goblet cells: 64.9;Paneth cells: 58.6;Proximal enterocytes: 60.3;Squamous epithelial cells: 40.3;Suprabasal keratinocytes: 66.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 44.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.9;naive B-cell: 2.2" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 60.1;Gastric cancer: 41.4" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002033, HPA050027" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 200000 "Cluster 14: Non-specific - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 59: Suprabasal keratinocytes - Cornification" "Golgi apparatus" Nucleoplasm "HPA002033: AB_1079650, HPA050027: " "unprognostic (2.23e-1)" "unprognostic (1.05e-1)" "unprognostic (2.54e-3)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.97e-1)" "unprognostic (3.39e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (1.86e-1)" "unprognostic (1.72e-1)" "unprognostic (1.30e-1)" "unprognostic (1.17e-2)" "unprognostic (2.50e-1)" "unprognostic (4.42e-2)" "unprognostic (1.07e-2)" "unprognostic (1.81e-1)" "unprognostic (5.57e-4)" "unprognostic (1.01e-2)" POLD4 "p12, POLDS" ENSG00000175482 "DNA polymerase delta 4, accessory subunit" Q9HCU8 11 67350772-67356972 "Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 265.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 405.6;Gastric mucus-secreting cells: 171.6;Intestinal goblet cells: 203.4;Paneth cells: 296.9;Proximal enterocytes: 366.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078008 Approved "Centriolar satellite" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 5: Enterocytes - Absorption" 4 "Centriolar satellite" "HPA078008: " "unprognostic (7.55e-3)" "unprognostic (2.71e-1)" "unprognostic (3.93e-2)" "unprognostic (2.75e-1)" "unprognostic (1.19e-2)" "unprognostic (1.03e-1)" "unprognostic (8.25e-2)" "unprognostic (1.43e-2)" "unprognostic (4.82e-1)" "unprognostic (2.02e-1)" "unprognostic (3.19e-2)" "unprognostic (2.53e-1)" "unprognostic (2.39e-3)" "unprognostic (1.70e-1)" "unprognostic (4.11e-2)" "unprognostic (1.95e-1)" "unprognostic (9.36e-2)" POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 303.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 416.2;Ionocytes: 315.1;Proximal enterocytes: 277.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 12000 "Cluster 35: Neutrophils - Protein binding" "Cluster 83: Liver - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 39: Non-specific - Transcription" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 Vesicles "Nucleoplasm, Cytosol" "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243755 "FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 40.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 105.9;Hepatocytes: 125.1;Proximal enterocytes: 87.3;Rod photoreceptor cells: 144.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 9.8;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 5 "dendritic cells: 2.9;granulocytes: 9.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058901, HPA067049, CAB075701" Supported Enhanced Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 35: Non-specific - Mitochondria" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 66: Photoreceptor cells - Visual perception" 18 Nucleoplasm "CAB075701: , HPA058901: AB_2683849, HPA067049: AB_2685770" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (3.94e-3)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (2.95e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" "unprognostic (1.01e-1)" "prognostic favorable (4.39e-9)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" PPP1R16A "MGC14333, MYPT3" ENSG00000160972 "Protein phosphatase 1 regulatory subunit 16A" Q96I34 8 144477969-144502121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 229.3;Proximal enterocytes: 441.4;Proximal tubular cells: 377.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" HPA023755 Uncertain Approved "Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 78: Testis - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 35 "Plasma membrane" "HPA023755: AB_1854268" "unprognostic (9.63e-2)" "unprognostic (4.51e-2)" "unprognostic (5.45e-3)" "unprognostic (3.11e-1)" "unprognostic (5.60e-2)" "unprognostic (3.75e-2)" "unprognostic (4.64e-3)" "unprognostic (2.65e-1)" "unprognostic (3.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" "unprognostic (1.29e-2)" "unprognostic (1.03e-1)" "unprognostic (9.45e-2)" "unprognostic (2.79e-2)" PRELID1 "CGI-106, PRELI, PX19" ENSG00000169230 "PRELI domain containing 1" Q9Y255 5 177303799-177306949 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 935.3;Syncytiotrophoblasts: 947.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005701 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Mixed function" Mitochondria Nucleoplasm "HPA005701: AB_1079721" "unprognostic (1.27e-1)" "unprognostic (8.99e-2)" "unprognostic (3.18e-2)" "unprognostic (2.09e-3)" "unprognostic (2.19e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (7.63e-3)" "unprognostic (1.49e-1)" "unprognostic (8.90e-3)" "unprognostic (1.71e-1)" "unprognostic (6.97e-2)" "prognostic unfavorable (2.89e-7)" "unprognostic (3.59e-2)" "unprognostic (1.15e-1)" "unprognostic (1.89e-1)" "unprognostic (2.21e-1)" PRELID2 "FLJ38376, MGC21644" ENSG00000186314 "PRELI domain containing 2" Q8N945 5 145471799-145835369 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.3;retina: 15.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 178.4;Inhibitory neurons: 402.6;Oligodendrocytes: 84.4;Proximal enterocytes: 116.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 24.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA042486 Uncertain Approved Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 65: Neurons - Synaptic function" Nucleoplasm "HPA042486: AB_10797498" "unprognostic (9.45e-3)" "unprognostic (1.95e-1)" "unprognostic (7.58e-3)" "unprognostic (2.71e-5)" "unprognostic (1.96e-3)" "unprognostic (6.53e-4)" "unprognostic (6.62e-5)" "unprognostic (2.27e-1)" "unprognostic (4.21e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (3.83e-1)" "prognostic unfavorable (9.65e-6)" "unprognostic (2.65e-1)" "unprognostic (1.29e-1)" "unprognostic (7.83e-4)" "unprognostic (6.42e-3)" PRKG2 "cGKII, PKG2, PRKGR2" ENSG00000138669 "Protein kinase cGMP-dependent 2" Q13237 4 81087370-81215222 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.3;prostate: 9.6" "Cell type enhanced" "Detected in some" "Excitatory neurons: 31.6;Inhibitory neurons: 63.1;Oligodendrocyte precursor cells: 100.0;Prostatic glandular cells: 25.7;Proximal enterocytes: 18.4" "Group enriched" "Detected in some" 4 "melanoma: 4.1;prostate cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007386, CAB018739" Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 15: Non-specific - Mixed function" "CAB018739: AB_2284387, HPA007386: AB_1079678" "unprognostic (6.14e-2)" "unprognostic (2.77e-1)" "unprognostic (2.14e-1)" "unprognostic (5.01e-4)" "unprognostic (4.33e-2)" "unprognostic (6.85e-2)" "unprognostic (1.13e-1)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.58e-1)" "unprognostic (4.00e-3)" "unprognostic (1.06e-1)" PRR13 "DKFZP564J157, FLJ23818" ENSG00000205352 "Proline rich 13" Q9NZ81 12 53441678-53446645 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 944.1;Distal tubular cells: 925.1;Proximal enterocytes: 1520.9;Proximal tubular cells: 829.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Lung - Neutrophil_2, Testis - Leydig cells" "Low region specificity" "Detected in all" "HPA039396, HPA046219" Uncertain Supported Nucleoplasm,Cytosol NA Yes "Cluster 7: Non-specific - Innate immune response" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 38: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 37 Nucleoplasm Cytosol "HPA039396: AB_2676484, HPA046219: AB_10963936" "unprognostic (1.09e-1)" "prognostic favorable (9.08e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-1)" "unprognostic (8.97e-3)" "unprognostic (4.88e-3)" "unprognostic (1.86e-3)" "unprognostic (7.23e-2)" "unprognostic (1.23e-1)" "unprognostic (3.49e-1)" "unprognostic (1.41e-2)" "unprognostic (5.41e-2)" "unprognostic (6.81e-3)" "unprognostic (1.81e-1)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "prognostic favorable (7.55e-4)" PRR15 ENSG00000176532 "Proline rich 15" Q8IV56 7 29563835-29567293 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 60.3;intestine: 78.6;stomach 1: 48.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 215.5;Granulosa cells: 134.7;Oocytes: 95.6;Proximal enterocytes: 117.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 75.5" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA040996, HPA048121" Enhanced Uncertain "Vesicles,Cell Junctions" NA NA "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 Vesicles "Cell Junctions" "HPA040996: AB_2677241, HPA048121: AB_2680271" "unprognostic (5.46e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "prognostic favorable (6.37e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (3.69e-3)" "unprognostic (1.25e-1)" "prognostic favorable (1.83e-6)" "unprognostic (1.30e-2)" "unprognostic (5.71e-2)" "unprognostic (2.33e-3)" "unprognostic (1.58e-2)" PRR15L "ATAD4, MGC11242" ENSG00000167183 "Proline rich 15 like" Q9BU68 17 47951967-47957883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 173.3;pancreas: 100.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 95.4;Distal enterocytes: 196.8;Enteroendocrine cells: 85.3;Intestinal goblet cells: 128.3;Paneth cells: 252.9;Proximal enterocytes: 248.9;Undifferentiated cells: 89.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 8 "choroid plexus: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 50.6;colorectal cancer: 47.9;Gastric cancer: 39.1" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 15.9" HPA022918 Approved Approved Cytosol No NA "Cluster 45: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" Cytosol "HPA022918: AB_2060743" "unprognostic (9.91e-2)" "unprognostic (4.77e-2)" "unprognostic (8.18e-2)" "unprognostic (5.75e-3)" "unprognostic (1.83e-1)" "unprognostic (2.31e-2)" "unprognostic (2.48e-1)" "unprognostic (5.22e-2)" "unprognostic (2.86e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (8.32e-2)" "prognostic favorable (6.29e-13)" "prognostic favorable (1.69e-5)" "unprognostic (1.36e-1)" "unprognostic (8.26e-2)" "unprognostic (3.34e-2)" PRRG2 PRGP2 ENSG00000126460 "Proline rich and Gla domain 2" O14669 19 49580646-49591004 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 27.4" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010702 Approved Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 2 "Nucleoplasm, Nucleoli" Cytosol "HPA010702: AB_1079693" "unprognostic (2.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (1.04e-2)" "unprognostic (1.04e-1)" "unprognostic (7.55e-2)" "unprognostic (5.60e-1)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (1.67e-1)" "prognostic favorable (3.82e-9)" "unprognostic (4.89e-2)" "unprognostic (1.46e-1)" "unprognostic (6.58e-3)" "unprognostic (3.68e-2)" PRSS36 FLJ90661 ENSG00000178226 "Serine protease 36" Q5K4E3 16 31138926-31150083 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 2.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.0;Hofbauer cells: 16.8;Proximal enterocytes: 48.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 2.0" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA036079 Uncertain "Secreted to extracellular matrix" Enzyme NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 45: Intestine - Digestion" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" "HPA036079: AB_10602290" "unprognostic (3.74e-2)" "prognostic favorable (2.97e-7)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (4.26e-3)" "unprognostic (1.31e-5)" "unprognostic (4.18e-2)" "unprognostic (5.05e-2)" "unprognostic (2.65e-2)" "unprognostic (8.03e-2)" "unprognostic (2.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (9.86e-2)" "unprognostic (1.23e-1)" "unprognostic (3.13e-1)" PRSS8 CAP1 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 238.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 303.3;Extravillous trophoblasts: 770.7;Proximal enterocytes: 331.5;Syncytiotrophoblasts: 632.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "cerebellum: 5.0;choroid plexus: 14.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in some" HPA030436 Uncertain "Secreted - unknown location" Enzyme NA NA 4400000 "Cluster 48: Stomach - Proteolysis" "Cluster 5: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" PRXL2B "C1orf93, FAM213B, MGC26818" ENSG00000157870 "Peroxiredoxin like 2B" Q8TBF2 1 2586491-2591469 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.4" "Cell type enhanced" "Detected in many" "Paneth cells: 46.7;Proximal enterocytes: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006403 Approved Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 2 Cytosol Nucleoplasm "HPA006403: AB_1853870" "unprognostic (1.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.03e-1)" "unprognostic (2.83e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.20e-1)" "unprognostic (8.76e-2)" "unprognostic (3.09e-2)" "unprognostic (1.24e-3)" "unprognostic (2.76e-1)" "prognostic favorable (1.28e-4)" "unprognostic (5.22e-3)" "unprognostic (2.03e-1)" "unprognostic (7.91e-3)" "unprognostic (2.20e-2)" PSMB10 "beta2i, LMP10, MECL1, MGC1665" ENSG00000205220 "Proteasome 20S subunit beta 10" P40306 16 67934506-67936864 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 119.4" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 145.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030224, HPA030225, CAB034384, CAB080377" Enhanced Approved Vesicles,Cytosol NA NA 1400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 7: T-cells - T-cell receptor" 7 "Vesicles, Cytosol" "CAB034384: AB_2171876, CAB080377: , HPA030224: AB_2673382, HPA030225: AB_10603231" "unprognostic (1.18e-2)" "unprognostic (1.90e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-3)" "unprognostic (2.00e-1)" "unprognostic (1.85e-2)" "unprognostic (7.22e-2)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-1)" "unprognostic (8.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.32e-2)" "unprognostic (2.97e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-2)" "prognostic favorable (5.44e-4)" PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome 20S subunit beta 8" P28062 6 32840717-32844679 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 335.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No 2700000 "Cluster 25: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" Vesicles "Cytokinetic bridge" "HPA046995: AB_2679896, HPA050327: AB_2681088" "prognostic favorable (5.08e-4)" "unprognostic (4.22e-2)" "unprognostic (2.39e-2)" "prognostic favorable (7.16e-4)" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (7.78e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-3)" "unprognostic (7.11e-3)" PSMB9 "beta1i, LMP2, PSMB6i, RING12" ENSG00000240065 "Proteasome 20S subunit beta 9" P28065 6 32844136-32859851 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 157.0" "Cell type enhanced" "Detected in many" "NK-cells: 326.2;Proximal enterocytes: 354.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015180, HPA042818, HPA053280" Enhanced Supported Cytosol NA NA 340000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 47: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 7 Cytosol "CAB015180: AB_2172368, HPA042818: AB_2678186, HPA053280: AB_2682098" "unprognostic (1.09e-2)" "unprognostic (1.68e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-3)" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (5.68e-2)" "unprognostic (6.67e-2)" "unprognostic (1.56e-2)" "unprognostic (6.50e-3)" "unprognostic (1.87e-3)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (2.65e-1)" "unprognostic (1.09e-1)" "unprognostic (4.96e-3)" "unprognostic (5.99e-2)" PSMD9 "p27, Rpn4" ENSG00000110801 "Proteasome 26S subunit, non-ATPase 9" O00233 12 121888732-121918297 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040512, HPA044220" Enhanced Supported "Plasma membrane,Cytosol" NA NA 500000 "Cluster 29: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 13 Cytosol "Plasma membrane" "HPA040512: AB_2677014, HPA044220: AB_2678860" "unprognostic (2.24e-1)" "unprognostic (2.48e-3)" "unprognostic (2.12e-1)" "unprognostic (3.36e-1)" "unprognostic (1.20e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.86e-1)" "unprognostic (6.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (9.64e-3)" "unprognostic (3.17e-2)" "unprognostic (5.73e-2)" "unprognostic (6.19e-2)" "unprognostic (8.63e-2)" PSME2 PA28beta ENSG00000100911 "Proteasome activator subunit 2" Q9UL46 14 24143362-24147570 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 738.0;Proximal enterocytes: 1085.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062661 Approved Nucleoplasm NA NA 5900000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 47: Spleen - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 15: Non-specific - Mixed function" 5 Nucleoplasm "HPA062661: AB_2684825" "prognostic favorable (1.27e-4)" "unprognostic (7.55e-3)" "unprognostic (2.84e-1)" "unprognostic (8.72e-2)" "unprognostic (2.69e-1)" "unprognostic (1.50e-1)" "unprognostic (3.71e-1)" "unprognostic (1.02e-1)" "unprognostic (2.30e-2)" "unprognostic (2.90e-3)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.47e-5)" "unprognostic (3.09e-2)" "unprognostic (3.00e-1)" "unprognostic (6.43e-3)" "unprognostic (3.07e-3)" PTGR1 "LTB4DH, ZADH3" ENSG00000106853 "Prostaglandin reductase 1" Q14914 9 111549722-111599893 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 271.0;liver: 576.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 419.1;Hepatocytes: 977.8;Proximal enterocytes: 1232.0;Proximal tubular cells: 457.0;Suprabasal keratinocytes: 857.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 6.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 6.0" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036724 Enhanced NA NA 2400000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "HPA036724: AB_10670239" "unprognostic (1.54e-1)" "unprognostic (2.23e-1)" "unprognostic (1.10e-2)" "unprognostic (3.02e-3)" "unprognostic (8.46e-2)" "unprognostic (1.02e-3)" "unprognostic (1.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (3.48e-1)" "prognostic favorable (5.53e-4)" "unprognostic (2.25e-1)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (5.22e-2)" PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 106.3;skin 1: 52.2;vagina: 41.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.7;Gastric mucus-secreting cells: 50.7;Intestinal goblet cells: 44.7;Paneth cells: 86.3;Proximal enterocytes: 73.9;Squamous epithelial cells: 55.5;Suprabasal keratinocytes: 81.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 34.3" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" 22 Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" PTPRH SAP-1 ENSG00000080031 "Protein tyrosine phosphatase receptor type H" Q9HD43 19 55181247-55209506 "Enzymes, Predicted membrane proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 23.4;intestine: 66.7;stomach 1: 23.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 74.7;Gastric mucus-secreting cells: 56.6;Intestinal goblet cells: 28.3;Paneth cells: 35.3;Proximal enterocytes: 106.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA008708 Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 30: White matter - Myelination" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 5: Enterocytes - Absorption" 4 "Nuclear speckles, Cytosol" "Plasma membrane" "HPA008708: " "unprognostic (1.87e-1)" "unprognostic (1.10e-1)" "unprognostic (2.59e-1)" "unprognostic (7.57e-3)" "unprognostic (5.01e-3)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (1.96e-3)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (9.96e-2)" "unprognostic (6.16e-2)" "unprognostic (1.47e-11)" "unprognostic (4.08e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-2)" "unprognostic (1.57e-1)" PXMP2 "MPV17L3, PMP22" ENSG00000176894 "Peroxisomal membrane protein 2" Q9NR77 12 132687587-132704985 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 304.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 232.8;Hepatocytes: 623.0;Proximal enterocytes: 352.5;Proximal tubular cells: 256.0" "Cancer enhanced" "Detected in all" "liver cancer: 43.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 43: Hepatocytes - Metabolism" 3 "unprognostic (1.12e-2)" "unprognostic (7.96e-2)" "unprognostic (4.70e-3)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (7.39e-3)" "unprognostic (2.83e-1)" "unprognostic (2.44e-2)" "unprognostic (3.02e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.75e-4)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.71e-3)" "unprognostic (3.04e-1)" PYCARD "ASC, CARD5, TMS-1" ENSG00000103490 "PYD and CARD domain containing" Q9ULZ3 16 31201486-31203450 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 82.7;skin 1: 87.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 534.9;Kupffer cells: 424.6;Macrophages: 349.1;Paneth cells: 407.9;Proximal enterocytes: 528.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 588.9;classical monocyte: 1101.6;eosinophil: 950.8;intermediate monocyte: 1140.1;myeloid DC: 830.8;neutrophil: 1647.4;non-classical monocyte: 1158.7;plasmacytoid DC: 771.2" "Group enriched" "Detected in all" 6 "dendritic cells: 830.8;granulocytes: 1647.4;monocytes: 1158.7" "Low cancer specificity" "Detected in many" "Lung - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006853, CAB015948, HPA049074, HPA054496" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol NA NA 640000 "Cluster 7: Non-specific - Innate immune response" "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 11 Nucleoplasm "Nucleoli, Cytosol" "CAB006853: , CAB015948: , HPA049074: AB_2680621, HPA054496: AB_2682506" "unprognostic (1.00e-3)" "unprognostic (2.62e-2)" "unprognostic (2.40e-1)" "unprognostic (4.67e-3)" "unprognostic (3.34e-1)" "unprognostic (1.87e-1)" "unprognostic (5.29e-2)" "unprognostic (2.88e-2)" "unprognostic (3.12e-1)" "unprognostic (2.33e-1)" "unprognostic (6.52e-3)" "unprognostic (3.88e-2)" "prognostic unfavorable (6.09e-7)" "unprognostic (4.45e-3)" "unprognostic (2.51e-1)" "unprognostic (3.61e-2)" "unprognostic (6.97e-2)" QTRT1 TGT ENSG00000213339 "Queuine tRNA-ribosyltransferase catalytic subunit 1" Q9BXR0 19 10701430-10713437 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 220.1;Intestinal goblet cells: 179.2;Paneth cells: 215.4;Proximal enterocytes: 256.8;Undifferentiated cells: 225.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042695, HPA048651, HPA049440" Approved Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 16: Intestinal goblet cells - Mucin production" 1 Mitochondria "HPA042695: AB_2678119, HPA048651: AB_2680477, HPA049440: AB_2680767" "unprognostic (6.19e-2)" "prognostic favorable (7.63e-5)" "unprognostic (2.90e-2)" "unprognostic (3.05e-1)" "unprognostic (4.90e-2)" "prognostic favorable (4.90e-4)" "unprognostic (2.52e-1)" "unprognostic (8.76e-3)" "unprognostic (3.88e-1)" "unprognostic (4.81e-3)" "prognostic favorable (2.13e-4)" "unprognostic (1.14e-2)" "prognostic unfavorable (1.13e-6)" "unprognostic (2.04e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" RAB17 ENSG00000124839 "RAB17, member RAS oncogene family" Q9H0T7 2 237574322-237601614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 74.1;intestine: 74.4;liver: 104.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 74.8;Distal tubular cells: 76.8;Hepatocytes: 113.0;Proximal enterocytes: 212.0;Proximal tubular cells: 142.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 14 "choroid plexus: 54.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA035176 Approved NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 22: Proximal enterocytes - Digestion" 4 "HPA035176: AB_10696368" "unprognostic (8.66e-2)" "unprognostic (1.13e-1)" "unprognostic (1.44e-3)" "unprognostic (9.14e-2)" "unprognostic (2.48e-3)" "unprognostic (1.26e-3)" "unprognostic (1.33e-1)" "unprognostic (5.36e-2)" "unprognostic (3.49e-2)" "unprognostic (2.68e-2)" "prognostic favorable (4.14e-4)" "unprognostic (5.87e-2)" "prognostic favorable (3.33e-13)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (3.44e-1)" "prognostic favorable (2.51e-4)" RAVER1 KIAA1978 ENSG00000161847 "Ribonucleoprotein, PTB binding 1" 19 10316212-10333529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 15.0;Enteroendocrine cells: 12.8;Erythroid cells: 17.2;Plasma cells: 12.6;Proximal enterocytes: 13.0;Undifferentiated cells: 12.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043575, HPA049457" Enhanced Supported Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" Nucleoplasm "HPA043575: AB_2678562, HPA049457: AB_2680774" "unprognostic (2.04e-1)" "unprognostic (3.15e-2)" "unprognostic (1.54e-1)" "unprognostic (2.34e-2)" "unprognostic (2.36e-1)" "unprognostic (1.80e-2)" "unprognostic (1.59e-1)" "unprognostic (4.22e-2)" "unprognostic (2.01e-2)" "unprognostic (7.20e-2)" "unprognostic (2.64e-2)" "unprognostic (3.22e-2)" "unprognostic (3.40e-2)" "unprognostic (1.14e-2)" "unprognostic (1.53e-1)" "unprognostic (8.98e-2)" "unprognostic (2.97e-1)" RBBP8NL "C20orf151, dJ908M14.3" ENSG00000130701 "RBBP8 N-terminal like" Q8NC74 20 62410237-62427539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 8.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 69.5;Enteroendocrine cells: 57.1;Intestinal goblet cells: 62.1;Paneth cells: 52.8;Proximal enterocytes: 149.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.1" "Colon - Colon enterocytes, Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA042627 Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 7: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 7 "Nucleoplasm, Vesicles" "HPA042627: AB_10797504" "unprognostic (8.99e-2)" "unprognostic (6.95e-3)" "unprognostic (2.71e-1)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (1.27e-3)" "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (2.76e-1)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "unprognostic (7.65e-3)" "prognostic favorable (6.91e-4)" RBKS "DKFZp686G13268, RBSK" ENSG00000171174 Ribokinase Q9H477 2 27781379-27890681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 45.0" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 87.4;Proximal tubular cells: 92.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019725, HPA028285" Enhanced Approved Nucleoplasm,Cytosol No No 11000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" 1 Cytosol Nucleoplasm "HPA019725: AB_1856105, HPA028285: AB_10601480" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" "unprognostic (2.51e-2)" "unprognostic (5.54e-3)" "unprognostic (4.15e-3)" "unprognostic (2.44e-1)" "unprognostic (1.43e-2)" "unprognostic (4.77e-2)" "unprognostic (2.45e-1)" "unprognostic (5.35e-2)" "unprognostic (1.46e-1)" "unprognostic (3.98e-1)" "unprognostic (1.20e-1)" "unprognostic (1.19e-1)" "unprognostic (1.72e-1)" "unprognostic (1.74e-1)" "unprognostic (9.27e-2)" RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 91.2;liver: 57.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 34.0;Proximal enterocytes: 35.7;Rod photoreceptor cells: 72.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 11: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 66: Photoreceptor cells - Visual perception" 1 Vesicles "HPA063345: AB_2684992" "unprognostic (1.04e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.05e-1)" "unprognostic (1.26e-3)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (3.46e-2)" "unprognostic (2.12e-3)" "unprognostic (3.27e-2)" RETSAT FLJ20296 ENSG00000042445 "Retinol saturase" Q6NUM9 2 85341955-85354531 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 238.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 190.4;Proximal enterocytes: 241.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007961 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Cytosol "HPA007961: AB_1079802" "unprognostic (6.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (5.84e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "prognostic favorable (4.23e-4)" "unprognostic (1.89e-1)" "unprognostic (2.16e-1)" "unprognostic (3.59e-2)" "unprognostic (1.77e-2)" "unprognostic (1.59e-1)" "prognostic favorable (1.95e-10)" "unprognostic (2.73e-2)" "unprognostic (5.34e-1)" "unprognostic (8.24e-3)" "unprognostic (9.90e-2)" RHOBTB2 "DBC2, KIAA0717" ENSG00000008853 "Rho related BTB domain containing 2" Q9BYZ6 8 22987417-23020509 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 51.3;lung: 49.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 126.9;Alveolar cells type 2: 159.8;Basal prostatic cells: 43.1;Proximal enterocytes: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060938 Approved Approved "Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 72: Alveolar cells - Lung function" "Plasma membrane" "HPA060938: AB_2684391" "unprognostic (2.67e-3)" "unprognostic (1.64e-1)" "unprognostic (1.64e-1)" "unprognostic (7.94e-2)" "unprognostic (7.83e-3)" "unprognostic (2.13e-2)" "unprognostic (8.13e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-3)" "unprognostic (1.93e-2)" "unprognostic (1.60e-2)" "unprognostic (1.46e-2)" "prognostic favorable (2.98e-4)" "unprognostic (2.01e-1)" "unprognostic (1.09e-1)" "unprognostic (8.89e-3)" "unprognostic (2.43e-1)" RHOC "ARH9, ARHC" ENSG00000155366 "Ras homolog family member C" P08134 1 112701127-112707434 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 961.1;Pancreatic endocrine cells: 842.2;Proximal enterocytes: 939.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1403.4" "Lineage enriched" "Detected in all" 4 "monocytes: 1403.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051461 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Non-specific - Mixed function" 2 "HPA051461: AB_2681493" "unprognostic (2.31e-2)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (1.93e-1)" "unprognostic (8.34e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (2.68e-4)" "unprognostic (2.08e-2)" "unprognostic (9.90e-2)" "unprognostic (1.40e-2)" "unprognostic (6.79e-3)" "unprognostic (3.95e-2)" "prognostic unfavorable (3.65e-5)" "unprognostic (1.26e-1)" "unprognostic (1.76e-1)" "unprognostic (3.08e-2)" "unprognostic (2.51e-3)" RHOF "ARHF, FLJ20247, RIF" ENSG00000139725 "Ras homolog family member F, filopodia associated" Q9HBH0 12 121777754-121803403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 130.2;Distal enterocytes: 148.9;Langerhans cells: 251.9;NK-cells: 122.9;Proximal enterocytes: 101.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045912, HPA076019" Enhanced Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 14: Langerhans cells - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA045912: , HPA076019: AB_2732299" "unprognostic (1.26e-1)" "unprognostic (8.73e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (1.90e-1)" "unprognostic (4.26e-5)" "unprognostic (1.38e-3)" "unprognostic (2.37e-4)" "unprognostic (1.34e-1)" "unprognostic (5.51e-2)" "unprognostic (1.10e-4)" "unprognostic (1.10e-1)" "unprognostic (5.01e-3)" "unprognostic (1.30e-1)" "unprognostic (2.02e-2)" "unprognostic (7.51e-4)" "unprognostic (1.14e-1)" RILP FLJ31193 ENSG00000167705 "Rab interacting lysosomal protein" Q96NA2 17 1646145-1649866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 58.6;skeletal muscle: 46.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 118.0;Proximal enterocytes: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.5;eosinophil: 1.0;intermediate monocyte: 1.2;myeloid DC: 2.4;neutrophil: 3.4;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.4;monocytes: 3.5" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" NA NA 18000 "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 8 "prognostic favorable (7.97e-4)" "unprognostic (7.93e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (4.11e-2)" "unprognostic (1.26e-1)" "unprognostic (1.50e-2)" "unprognostic (8.84e-3)" "unprognostic (1.61e-1)" "unprognostic (2.64e-1)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "prognostic favorable (8.51e-5)" "unprognostic (2.26e-1)" "unprognostic (4.73e-2)" "unprognostic (1.00e-1)" "prognostic favorable (7.12e-4)" RIPK3 RIP3 ENSG00000129465 "Receptor interacting serine/threonine kinase 3" Q9Y572 14 24336025-24340022 "Enzymes, Predicted intracellular proteins, Transporters" "Apoptosis, Host-virus interaction, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.8;Exocrine glandular cells: 23.7;Proximal enterocytes: 22.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.2" "Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 14: Langerhans cells - Innate immune response" 5 "unprognostic (1.85e-2)" "unprognostic (1.66e-1)" "unprognostic (5.16e-3)" "unprognostic (1.12e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-1)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-2)" "unprognostic (1.11e-1)" "unprognostic (5.26e-3)" "unprognostic (9.58e-2)" "unprognostic (5.58e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-2)" RITA1 "C12orf52, FLJ14827, RITA" ENSG00000139405 "RBPJ interacting and tubulin associated 1" Q96K30 12 113185526-113192368 "Predicted intracellular proteins" "Neurogenesis, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 67.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039094, HPA039095, HPA061531" Supported Supported Nucleoplasm No No "Cluster 41: Basophils - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 22: Proximal enterocytes - Digestion" 3 Nucleoplasm "HPA039094: AB_10671037, HPA039095: AB_2676345, HPA061531: AB_2684554" "unprognostic (7.10e-2)" "unprognostic (4.26e-2)" "unprognostic (2.78e-2)" "unprognostic (3.55e-2)" "unprognostic (2.56e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.47e-2)" "unprognostic (2.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" "unprognostic (1.98e-1)" "unprognostic (2.59e-3)" "unprognostic (1.44e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" RNASEK-C17orf49 ENSG00000161939 "RNASEK-C17orf49 readthrough" 17 7012635-7017520 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.1;Ductal cells: 6.4;Exocrine glandular cells: 3.8;Pancreatic endocrine cells: 8.5;Proximal enterocytes: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA022961, HPA024457" Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" Nucleoplasm Cytosol "HPA022961: AB_1845592, HPA024457: AB_1845593" "unprognostic (4.08e-2)" "unprognostic (3.30e-1)" "unprognostic (1.58e-1)" "unprognostic (9.37e-5)" "unprognostic (4.19e-1)" "unprognostic (1.71e-1)" "unprognostic (7.91e-2)" "unprognostic (3.01e-2)" "unprognostic (2.52e-1)" "unprognostic (2.87e-1)" "unprognostic (3.77e-3)" "unprognostic (8.26e-3)" "unprognostic (8.58e-3)" "unprognostic (3.00e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-1)" "unprognostic (1.78e-1)" RNF128 "FLJ23516, GRAIL" ENSG00000133135 "Ring finger protein 128" Q8TEB7 X 106693794-106797016 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 60.3;liver: 120.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 42.0;Distal enterocytes: 41.1;Gastric mucus-secreting cells: 47.2;Hepatocytes: 62.6;Intestinal goblet cells: 40.9;Proximal enterocytes: 73.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Hepatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019675 Uncertain NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 4 "HPA019675: AB_2670225" "unprognostic (1.78e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-3)" "unprognostic (1.92e-4)" "unprognostic (2.14e-3)" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (1.55e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.07e-7)" "unprognostic (1.11e-2)" "unprognostic (7.61e-2)" "unprognostic (6.30e-2)" "unprognostic (5.30e-3)" RNF5 "G16, NG2, RING5, RMA1" ENSG00000204308 "Ring finger protein 5" Q99942 6 32178405-32180793 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 270.6;Proximal tubular cells: 321.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034107, HPA065032" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 22: Proximal enterocytes - Digestion" 44 "Endoplasmic reticulum" "CAB034107: AB_2238618, HPA065032: AB_2685408" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.45e-3)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (4.07e-1)" "prognostic favorable (2.44e-4)" "unprognostic (1.95e-1)" "unprognostic (8.93e-3)" "unprognostic (2.91e-3)" "unprognostic (8.84e-2)" "unprognostic (9.17e-2)" "unprognostic (2.72e-1)" "unprognostic (2.99e-2)" RNPEP APB ENSG00000176393 "Arginyl aminopeptidase" Q9H4A4 1 201982372-202006147 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 196.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 19.8;granulocytes: 23.2;monocytes: 30.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036074, HPA036075, HPA061487" Approved Approved "Golgi apparatus" "Secreted - unknown location" Enzyme NA NA 7800000 "Cluster 25: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 58: Macrophages - Innate immune response" "Golgi apparatus" "HPA036074: AB_2674926, HPA036075: AB_10672999, HPA061487: AB_2684537" "unprognostic (8.57e-2)" "unprognostic (3.43e-2)" "unprognostic (2.81e-1)" "unprognostic (5.45e-2)" "unprognostic (2.68e-1)" "unprognostic (1.74e-2)" "unprognostic (1.95e-2)" "unprognostic (2.87e-2)" "unprognostic (1.93e-3)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (3.50e-3)" "unprognostic (1.91e-1)" "unprognostic (6.00e-2)" "unprognostic (1.97e-2)" "unprognostic (1.68e-1)" RORC "NR1F3, RORG, RZRG, TOR" ENSG00000143365 "RAR related orphan receptor C" P51449 1 151806071-151831845 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 84.1;skeletal muscle: 123.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 33.8;Hepatocytes: 50.4;Proximal enterocytes: 31.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebellum: 4.3;choroid plexus: 8.4;midbrain: 2.5" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 50.2" "Lineage enriched" "Detected in many" 44 "T-cells: 50.2" "Cancer enhanced" "Detected in many" "breast cancer: 4.8;prostate cancer: 4.8" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065620 Supported "Nuclear bodies" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 17: Breast glandular cells - Lactation" 1 "Nuclear bodies" "HPA065620: AB_2685521" "unprognostic (6.51e-2)" "unprognostic (7.78e-2)" "prognostic favorable (1.83e-4)" "unprognostic (9.20e-2)" "unprognostic (3.05e-4)" "unprognostic (6.29e-5)" "unprognostic (1.13e-3)" "unprognostic (8.94e-2)" "unprognostic (1.67e-1)" "unprognostic (7.88e-2)" "unprognostic (3.78e-2)" "unprognostic (2.42e-1)" "prognostic favorable (2.94e-5)" "unprognostic (2.13e-1)" "unprognostic (3.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.80e-2)" RPP25L "bA296L22.5, C9orf23, MGC29635" ENSG00000164967 "Ribonuclease P/MRP subunit p25 like" Q8N5L8 9 34610486-34612104 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 114.2" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 129.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052187, HPA059698" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 5: Enterocytes - Absorption" 5 Nucleoplasm "Nucleoli, Cytosol" "HPA052187: AB_2681755, HPA059698: AB_2684106" "unprognostic (1.56e-1)" "unprognostic (1.43e-2)" "unprognostic (7.44e-2)" "unprognostic (1.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.78e-1)" "unprognostic (4.78e-2)" "unprognostic (2.56e-1)" "unprognostic (1.66e-1)" "unprognostic (2.53e-2)" "unprognostic (3.39e-2)" "unprognostic (2.44e-1)" "prognostic favorable (3.01e-9)" "unprognostic (4.63e-3)" "unprognostic (6.20e-2)" "unprognostic (3.40e-1)" "prognostic favorable (8.21e-4)" RPS27L ENSG00000185088 "Ribosomal protein S27 like" Q71UM5 15 63125872-63158021 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1489.8;Proximal enterocytes: 1520.9;Proximal tubular cells: 2496.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066851 Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 15: Non-specific - Mixed function" 1 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA066851: AB_2685737" "unprognostic (4.62e-2)" "unprognostic (5.81e-2)" "unprognostic (1.38e-1)" "prognostic favorable (9.08e-6)" "unprognostic (1.75e-1)" "unprognostic (7.24e-2)" "unprognostic (1.42e-3)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (1.80e-1)" "unprognostic (2.19e-3)" "unprognostic (2.51e-1)" "unprognostic (1.97e-2)" "unprognostic (5.31e-2)" "unprognostic (1.36e-1)" "unprognostic (1.97e-3)" "unprognostic (5.10e-3)" RPS6KA1 "HU-1, MAPKAPK1, p90Rsk, RSK1" ENSG00000117676 "Ribosomal protein S6 kinase A1" Q15418 1 26529761-26575030 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 69.0;Proximal enterocytes: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003852, HPA007981" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 74: Neutrophils - Degranulation" 7 Cytosol Nucleoplasm "CAB003852: AB_289590, HPA007981: AB_1079850" "unprognostic (1.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.61e-3)" "prognostic favorable (7.20e-7)" "unprognostic (7.35e-2)" "unprognostic (3.69e-1)" "unprognostic (6.93e-3)" "unprognostic (1.12e-2)" "unprognostic (1.09e-1)" "unprognostic (7.51e-3)" "unprognostic (2.37e-2)" "unprognostic (9.64e-2)" "prognostic favorable (1.84e-4)" "prognostic favorable (4.58e-4)" "unprognostic (4.77e-2)" "unprognostic (7.61e-2)" "prognostic favorable (8.33e-4)" SAT2 SSAT2 ENSG00000141504 "Spermidine/spermine N1-acetyltransferase family member 2" Q96F10 17 7626234-7627876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 974.8;Proximal tubular cells: 1197.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022136, HPA057096" Enhanced NA NA 11000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 "HPA022136: AB_1856592, HPA057096: AB_2683334" "unprognostic (2.61e-2)" "unprognostic (1.27e-2)" "unprognostic (3.23e-2)" "prognostic favorable (8.76e-6)" "unprognostic (2.18e-2)" "unprognostic (2.32e-1)" "unprognostic (7.20e-2)" "prognostic favorable (6.71e-4)" "unprognostic (4.14e-2)" "unprognostic (2.75e-1)" "prognostic favorable (6.05e-5)" "unprognostic (1.83e-1)" "unprognostic (6.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (1.50e-1)" "unprognostic (3.12e-2)" SCIN KIAA1905 ENSG00000006747 Scinderin Q9Y6U3 7 12570577-12660182 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 45.1;kidney: 45.4;placenta: 75.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 299.5;Early spermatids: 117.4;Paneth cells: 162.4;Proximal enterocytes: 290.5" "Cancer enhanced" "Detected in many" "renal cancer: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020518, HPA024264" Enhanced Approved "Plasma membrane,Cytosol" No No 2300000 "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane" Cytosol "HPA020518: AB_1856619, HPA024264: AB_1856621" "unprognostic (3.68e-1)" "unprognostic (4.98e-2)" "unprognostic (5.05e-1)" "unprognostic (2.47e-1)" "unprognostic (1.50e-1)" "unprognostic (5.98e-2)" "unprognostic (3.64e-5)" "unprognostic (1.31e-2)" "unprognostic (3.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.24e-1)" "prognostic favorable (4.26e-8)" "unprognostic (3.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.13e-2)" "unprognostic (3.18e-1)" SCP2 ENSG00000116171 "Sterol carrier protein 2" P22307 1 52927276-53051698 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1081.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 1183.6;Proximal enterocytes: 765.5;Proximal tubular cells: 827.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "HPA027101, HPA027135, HPA027317" Supported Supported Nucleoplasm,Peroxisomes NA NA 640000 "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 43: Hepatocytes - Metabolism" 2 Peroxisomes Nucleoplasm "HPA027101: AB_1856634, HPA027135: AB_1856633, HPA027317: AB_10610422" "unprognostic (7.51e-2)" "unprognostic (5.23e-2)" "prognostic favorable (7.05e-5)" "unprognostic (9.68e-2)" "unprognostic (1.53e-2)" "unprognostic (5.53e-2)" "unprognostic (1.87e-3)" "unprognostic (1.22e-2)" "unprognostic (1.62e-2)" "unprognostic (1.59e-1)" "unprognostic (4.53e-2)" "unprognostic (6.16e-2)" "prognostic favorable (7.85e-8)" "unprognostic (1.49e-2)" "unprognostic (1.09e-1)" "unprognostic (8.64e-2)" "unprognostic (1.13e-2)" SDCBP2 "SITAC18, ST-2" ENSG00000125775 "Syndecan binding protein 2" Q9H190 20 1309909-1329139 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 137.9;intestine: 133.0;stomach 1: 99.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 217.8;Distal enterocytes: 700.5;Ionocytes: 269.1;Paneth cells: 640.0;Proximal enterocytes: 476.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gastric cancer: 28.9" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005804, HPA064490" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Non-specific - Mixed function" 49 Nucleoplasm "Golgi apparatus, Cytosol" "HPA005804: , HPA064490: AB_2732713" "unprognostic (1.96e-2)" "unprognostic (5.44e-2)" "unprognostic (2.37e-1)" "unprognostic (5.85e-2)" "unprognostic (2.54e-1)" "unprognostic (2.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (1.01e-1)" "unprognostic (3.78e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (3.17e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.37e-4)" SDF4 Cab45 ENSG00000078808 "Stromal cell derived factor 4" 1 1216931-1232031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 299.5;Proximal enterocytes: 345.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011249, HPA011895, CAB015227" Supported Supported Supported "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" "Golgi apparatus" "CAB015227: , HPA011249: AB_2668468, HPA011895: " "unprognostic (1.98e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (3.63e-1)" "unprognostic (2.38e-3)" "unprognostic (5.88e-2)" "unprognostic (7.95e-3)" "unprognostic (3.73e-3)" "unprognostic (1.06e-1)" "unprognostic (2.01e-1)" "unprognostic (8.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (3.04e-2)" SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218303-257082 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Neurodegeneration, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 554.8;skeletal muscle: 459.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 453.4;Proximal enterocytes: 257.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034929, HPA041981, HPA064582" Enhanced Supported Nucleoli,Mitochondria No No 360000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 68: Cardiomyocytes - Muscle contraction" 5 Mitochondria Nucleoli "CAB034929: AB_2183443, HPA041981: AB_2677779, HPA064582: AB_2685293" "prognostic unfavorable (6.00e-4)" "unprognostic (1.93e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (1.62e-1)" "unprognostic (2.80e-1)" "unprognostic (3.14e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "prognostic favorable (9.53e-8)" "unprognostic (1.11e-2)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (1.79e-1)" SDR42E2 ENSG00000183921 "Short chain dehydrogenase/reductase family 42E, member 2" A6NKP2 16 22162492-22192208 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "fallopian tube: 2.1;testis: 2.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 22.2;Proximal enterocytes: 35.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "neutrophil: 5.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.3" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (8.03e-3)" "unprognostic (2.80e-1)" "unprognostic (2.06e-1)" "unprognostic (1.72e-4)" "unprognostic (1.85e-1)" "unprognostic (7.07e-2)" "unprognostic (8.77e-2)" "unprognostic (3.72e-1)" "unprognostic (4.25e-1)" "unprognostic (1.27e-1)" "unprognostic (6.32e-3)" "unprognostic (2.01e-1)" "unprognostic (7.09e-2)" "unprognostic (4.76e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (6.61e-2)" SEC14L2 "C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1" ENSG00000100003 "SEC14 like lipid binding 2" O76054 22 30396941-30425303 "Predicted intracellular proteins" "Transcription, Transcription regulation, Transport" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 83.9;liver: 236.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 139.2;Muller glia cells: 91.7;Proximal enterocytes: 49.3;Rod photoreceptor cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.8;naive CD8 T-cell: 2.7" "Lineage enriched" "Detected in single" 7 "T-cells: 3.8" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064466 Approved Supported Nucleoplasm,Cytosol NA NA 580000 "Cluster 24: Non-specific - Transcription" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 45: Non-specific - Mixed function" Nucleoplasm Cytosol "HPA064466: AB_2685270" "prognostic favorable (3.05e-4)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (5.59e-3)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.63e-6)" "unprognostic (1.25e-3)" "unprognostic (3.76e-3)" "unprognostic (2.23e-1)" "unprognostic (2.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.63e-3)" "unprognostic (1.17e-3)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-3)" "unprognostic (2.01e-1)" SECTM1 K12 ENSG00000141574 "Secreted and transmembrane 1" Q8WVN6 17 82321024-82334074 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 87.8" "Cell type enhanced" "Detected in many" "Kupffer cells: 86.3;Macrophages: 38.5;monocytes: 126.0;Mucus glandular cells: 48.3;Oocytes: 49.3;Proximal enterocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 155.2" "Group enriched" "Detected in many" 13 "granulocytes: 155.2;monocytes: 58.3" "Low cancer specificity" "Detected in many" "Stomach - Macrophages" "Low region specificity" "Detected in many" HPA051214 Approved "Secreted to blood" "No annotated function" NA NA 16000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 1 "HPA051214: AB_2732565" "unprognostic (2.42e-1)" "unprognostic (2.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.69e-2)" "unprognostic (4.29e-2)" "unprognostic (1.15e-2)" "unprognostic (4.55e-2)" "unprognostic (9.39e-2)" "unprognostic (3.17e-3)" "unprognostic (7.75e-3)" "unprognostic (2.10e-2)" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.43e-1)" "unprognostic (4.31e-3)" "unprognostic (2.84e-1)" "unprognostic (1.01e-1)" SEMA3B "LUCA-1, SemA, sema5, SEMAA, semaV" ENSG00000012171 "Semaphorin 3B" Q13214 3 50267558-50277546 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 169.0;brain: 162.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 177.0;Gastric mucus-secreting cells: 196.3;Oligodendrocytes: 146.9;Proximal enterocytes: 305.7;Schwann cells: 321.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 82.3" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Lung - Alveolar cells type 1, Skin - Fibroblast_1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 36.8" HPA030651 Uncertain "Secreted in other tissues" "Developmental protein" NA NA 790000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" "HPA030651: AB_10602224" "prognostic favorable (1.27e-4)" "unprognostic (6.48e-2)" "unprognostic (5.40e-2)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (4.15e-1)" "unprognostic (1.89e-1)" "unprognostic (2.83e-2)" "unprognostic (2.21e-2)" "unprognostic (2.28e-1)" "unprognostic (1.85e-2)" "unprognostic (4.27e-1)" "unprognostic (7.99e-2)" "unprognostic (7.78e-2)" "unprognostic (3.89e-1)" "unprognostic (8.87e-3)" "unprognostic (1.69e-2)" SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969504-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 59.0;Hepatocytes: 46.1;Intestinal goblet cells: 35.2;Paneth cells: 37.8;Proximal enterocytes: 45.4;Undifferentiated cells: 23.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" "Developmental protein" NA NA 1300000 "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" SEPHS2 "SPS2, SPS2b" ENSG00000179918 "Selenophosphate synthetase 2" Q99611 16 30443631-30445874 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 390.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 390.1;Proximal enterocytes: 386.3;Proximal tubular cells: 325.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Macrophages" "Low region specificity" "Detected in all" HPA047931 Approved Approved Nucleoplasm No No 29000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" Nucleoplasm "HPA047931: AB_2680216" "unprognostic (5.33e-2)" "unprognostic (2.02e-1)" "unprognostic (1.92e-2)" "unprognostic (9.85e-2)" "unprognostic (2.67e-2)" "unprognostic (6.29e-2)" "unprognostic (5.67e-2)" "unprognostic (7.69e-3)" "unprognostic (2.38e-1)" "unprognostic (9.86e-2)" "unprognostic (9.66e-3)" "unprognostic (1.49e-1)" "prognostic favorable (4.35e-8)" "unprognostic (2.24e-2)" "unprognostic (1.35e-1)" "unprognostic (3.25e-2)" "unprognostic (3.62e-2)" SERINC2 "FKSG84, PRO0899, TDE2, TDE2L" ENSG00000168528 "Serine incorporator 2" Q96SA4 1 31409565-31434680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 229.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 358.9;Cytotrophoblasts: 454.0;Distal enterocytes: 545.6;Ductal cells: 715.9;Proximal enterocytes: 402.0;Syncytiotrophoblasts: 404.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 10.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 10.4" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA005974 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" Nucleoplasm "HPA005974: AB_10603239" "unprognostic (1.41e-1)" "unprognostic (3.70e-3)" "unprognostic (8.78e-3)" "prognostic favorable (1.69e-7)" "unprognostic (6.78e-2)" "unprognostic (5.31e-2)" "prognostic unfavorable (2.11e-4)" "prognostic unfavorable (5.70e-4)" "unprognostic (3.12e-2)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.09e-2)" "unprognostic (3.74e-2)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (4.63e-3)" "unprognostic (2.67e-2)" SFXN3 "SFX3, SLC56A3" ENSG00000107819 "Sideroflexin 3" Q9BWM7 10 101031234-101041241 "Metabolic proteins, Predicted membrane proteins" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 189.4;Proximal enterocytes: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008028, HPA048105" Approved Enhanced Mitochondria NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Late spermatids - Spermatogenesis" 16 Mitochondria "HPA008028: AB_1079938, HPA048105: AB_2680265" "unprognostic (2.55e-1)" "unprognostic (3.32e-2)" "unprognostic (4.94e-2)" "unprognostic (2.82e-2)" "unprognostic (4.94e-3)" "prognostic unfavorable (3.79e-4)" "unprognostic (3.84e-3)" "unprognostic (8.46e-2)" "unprognostic (1.05e-2)" "unprognostic (9.09e-3)" "unprognostic (1.04e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (3.56e-1)" "unprognostic (3.05e-2)" "unprognostic (3.70e-2)" "unprognostic (1.71e-1)" SGK1 SGK ENSG00000118515 "Serum/glucocorticoid regulated kinase 1" O00141 6 134169248-134318112 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 972.4" "Cell type enhanced" "Detected in all" "Langerhans cells: 1457.0;Proximal enterocytes: 708.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 43.5;eosinophil: 170.2;neutrophil: 91.8" "Group enriched" "Detected in all" 8 "granulocytes: 170.2;monocytes: 43.5" "Cancer enhanced" "Detected in all" "skin cancer: 215.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022085, CAB025148, HPA051251" Approved Enhanced "Nuclear speckles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 28: Dendritic cells - Antigen presentation" 5 "Nuclear speckles" "CAB022085: , CAB025148: , HPA051251: AB_2681407" "unprognostic (2.05e-2)" "prognostic favorable (5.26e-4)" "unprognostic (1.12e-1)" "unprognostic (5.09e-3)" "unprognostic (2.76e-1)" "unprognostic (4.20e-2)" "unprognostic (4.53e-2)" "unprognostic (5.62e-2)" "unprognostic (4.03e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (2.55e-1)" "unprognostic (5.82e-3)" "unprognostic (9.10e-2)" "unprognostic (3.81e-2)" "unprognostic (1.79e-1)" "unprognostic (6.59e-2)" SGK2 ENSG00000101049 "Serum/glucocorticoid regulated kinase 2" Q9HBY8 20 43558968-43588237 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.4;kidney: 53.8;liver: 63.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 88.3;Distal tubular cells: 67.6;Hepatocytes: 36.3;Oligodendrocytes: 19.3;Proximal enterocytes: 27.5" "Cancer enhanced" "Detected in many" "liver cancer: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 30.0" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Sebaceous gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008859, HPA011387" Uncertain Supported Nucleoplasm NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 Nucleoplasm "HPA008859: AB_2668159, HPA011387: AB_1856744" "unprognostic (1.82e-1)" "unprognostic (1.84e-1)" "unprognostic (4.53e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.98e-4)" "unprognostic (2.05e-2)" "unprognostic (1.35e-1)" "unprognostic (4.30e-2)" "unprognostic (2.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.72e-4)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (2.56e-1)" "unprognostic (3.11e-2)" "prognostic favorable (5.65e-4)" SH3D21 "C1orf113, FLJ22938" ENSG00000214193 "SH3 domain containing 21" A4FU49 1 36306368-36329340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.3;thyroid gland: 26.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 24.5;Late spermatids: 51.9;Proximal enterocytes: 23.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042212, HPA042456, HPA066168" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Late spermatids - Spermatogenesis" 1 "Nucleoplasm, Plasma membrane" "HPA042212: AB_10961180, HPA042456: AB_10959746, HPA066168: AB_2685627" "prognostic favorable (2.60e-4)" "unprognostic (8.35e-3)" "unprognostic (3.86e-3)" "unprognostic (9.01e-2)" "unprognostic (2.07e-3)" "unprognostic (7.32e-3)" "unprognostic (2.04e-4)" "unprognostic (7.47e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.43e-2)" "unprognostic (7.38e-3)" "prognostic unfavorable (1.76e-6)" "unprognostic (8.88e-2)" "unprognostic (2.25e-1)" "unprognostic (7.99e-2)" "unprognostic (8.59e-2)" SHROOM1 "APXL2, KIAA1960" ENSG00000164403 "Shroom family member 1" Q2M3G4 5 132822141-132830659 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 114.0;prostate: 71.6;urinary bladder: 60.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 116.5;Hepatocytes: 58.4;Prostatic glandular cells: 59.7;Proximal enterocytes: 57.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037690, HPA037691" Uncertain Approved Vesicles NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA037690: AB_2675613, HPA037691: AB_2675614" "unprognostic (2.50e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (2.66e-1)" "unprognostic (1.45e-2)" "unprognostic (3.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.33e-2)" "unprognostic (3.74e-1)" "unprognostic (3.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.22e-2)" "unprognostic (2.91e-2)" "unprognostic (2.88e-2)" "unprognostic (2.26e-3)" SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 101.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 110.6;Proximal enterocytes: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" Enzyme NA NA 2200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favorable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favorable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" SLC10A5 ENSG00000253598 "Solute carrier family 10 member 5" Q5PT55 8 81693631-81695058 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 11.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4.3;Gastric mucus-secreting cells: 7.1;Hepatocytes: 3.0;Intestinal goblet cells: 3.8;Ionocytes: 2.6;Paneth cells: 2.8;Proximal enterocytes: 6.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes" "Not detected" "Not detected" HPA025966 Uncertain Approved "Plasma membrane" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 16: Intestinal goblet cells - Mucin production" "Plasma membrane" "HPA025966: AB_1856959" "unprognostic (6.42e-2)" "unprognostic (3.89e-1)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (8.13e-3)" "unprognostic (1.91e-1)" "unprognostic (5.71e-2)" "unprognostic (5.63e-2)" "unprognostic (3.67e-1)" "unprognostic (2.41e-1)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (8.95e-2)" "unprognostic (2.51e-1)" "unprognostic (2.24e-1)" "unprognostic (1.67e-1)" "unprognostic (2.82e-7)" SLC16A5 "MCT5, MCT6" ENSG00000170190 "Solute carrier family 16 member 5" O15375 17 75087727-75106162 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 90.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 45.2;Collecting duct cells: 83.6;Late spermatids: 40.8;Paneth cells: 33.6;Proximal enterocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.2;neutrophil: 35.1" "Group enriched" "Detected in all" 6 "granulocytes: 35.1;monocytes: 13.2" "Low cancer specificity" "Detected in many" "Liver - Vascular Endothelial cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 2 "unprognostic (1.86e-2)" "unprognostic (1.18e-1)" "unprognostic (1.98e-1)" "unprognostic (2.51e-2)" "unprognostic (2.90e-2)" "unprognostic (2.72e-1)" "unprognostic (6.30e-2)" "unprognostic (2.55e-1)" "unprognostic (1.61e-1)" "unprognostic (5.26e-2)" "unprognostic (8.43e-3)" "unprognostic (8.07e-2)" "unprognostic (9.63e-2)" "unprognostic (3.53e-3)" "unprognostic (5.44e-2)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" SLC1A1 "EAAC1, EAAT3, hEAAC1" ENSG00000106688 "Solute carrier family 1 member 1" P43005 9 4490468-4587469 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 43.9;intestine: 62.9;kidney: 49.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 65.3;Excitatory neurons: 46.8;Glandular and luminal cells: 120.6;Hepatocytes: 57.7;Inhibitory neurons: 47.9;Microglial cells: 64.4;Oligodendrocyte precursor cells: 151.4;Proximal enterocytes: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062356 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Glandular & Luminal cells - Unknown function" 8 "HPA062356: " "unprognostic (1.28e-2)" "unprognostic (2.37e-2)" "unprognostic (6.83e-3)" "unprognostic (3.07e-3)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.71e-1)" "unprognostic (1.35e-2)" "unprognostic (1.25e-2)" "prognostic favorable (2.86e-8)" "unprognostic (2.68e-1)" "unprognostic (9.49e-2)" "unprognostic (7.78e-2)" "unprognostic (2.64e-1)" SLC22A18 "BWR1A, BWSCR1A, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5" ENSG00000110628 "Solute carrier family 22 member 18" Q96BI1 11 2899721-2925246 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.9;liver: 44.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 390.5;Late spermatids: 503.2;Paneth cells: 258.5;Proximal enterocytes: 763.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA067812, HPA071461" Enhanced NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 4 "HPA067812: AB_2685902, HPA071461: AB_2686401" "unprognostic (1.10e-1)" "unprognostic (1.14e-1)" "unprognostic (4.80e-1)" "unprognostic (7.75e-2)" "unprognostic (7.92e-3)" "unprognostic (2.67e-1)" "unprognostic (8.25e-2)" "unprognostic (4.21e-1)" "unprognostic (2.56e-2)" "unprognostic (3.48e-2)" "unprognostic (9.35e-2)" "unprognostic (8.60e-2)" "unprognostic (8.36e-2)" "unprognostic (9.51e-2)" "unprognostic (5.97e-3)" "unprognostic (1.55e-1)" "unprognostic (2.82e-1)" SLC22A5 "CDSP, OCTN2, SCD" ENSG00000197375 "Solute carrier family 22 member 5" O76082 5 132369710-132395613 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 54.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 50.9;Proximal enterocytes: 44.8" "Cancer enhanced" "Detected in all" "renal cancer: 8.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA063062 Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 79: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 3 Mitochondria "HPA063062: AB_2684934" "unprognostic (3.88e-1)" "unprognostic (1.69e-1)" "unprognostic (2.19e-2)" "prognostic favorable (2.87e-5)" "unprognostic (5.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.50e-2)" "unprognostic (9.24e-2)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (7.36e-4)" "unprognostic (3.53e-2)" "prognostic favorable (8.36e-4)" "unprognostic (1.12e-2)" "unprognostic (2.98e-2)" "unprognostic (2.17e-2)" "unprognostic (1.17e-2)" SLC25A1 "CTP, SLC20A3" ENSG00000100075 "Solute carrier family 25 member 1" P53007 22 19175581-19178739 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Antiport, Transport" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 192.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 199.4;Proximal enterocytes: 296.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 102.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (2.12e-1)" "unprognostic (3.98e-1)" "unprognostic (8.17e-2)" "unprognostic (1.13e-1)" "unprognostic (9.39e-2)" "unprognostic (2.61e-2)" "unprognostic (3.11e-2)" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (5.74e-2)" "unprognostic (3.90e-2)" "unprognostic (5.72e-2)" "unprognostic (4.52e-2)" "unprognostic (1.84e-1)" "unprognostic (3.46e-2)" "unprognostic (6.14e-2)" "unprognostic (9.03e-2)" SLC25A10 DIC ENSG00000183048 "Solute carrier family 25 member 10" Q9UBX3 17 81712236-81721016 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Lipid transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 178.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 52.7;Late spermatids: 76.3;Proximal enterocytes: 53.3;Proximal tubular cells: 67.5;Undifferentiated cells: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023048 Supported Supported Nucleoplasm,Mitochondria NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 6 Mitochondria Nucleoplasm "HPA023048: AB_2301950" "unprognostic (7.17e-2)" "unprognostic (2.38e-2)" "unprognostic (2.36e-2)" "unprognostic (1.36e-1)" "unprognostic (9.50e-2)" "prognostic favorable (2.56e-4)" "unprognostic (5.66e-2)" "unprognostic (2.11e-1)" "unprognostic (1.78e-2)" "prognostic favorable (8.14e-4)" "unprognostic (6.73e-2)" "unprognostic (1.33e-1)" "unprognostic (6.02e-2)" "unprognostic (6.32e-2)" "unprognostic (2.76e-1)" "unprognostic (2.05e-1)" "prognostic favorable (1.31e-4)" SLC25A20 "CAC, CACT" ENSG00000178537 "Solute carrier family 25 member 20" O43772 3 48856926-48898904 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 143.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 50.7;Distal enterocytes: 34.7;Hepatocytes: 62.0;Proximal enterocytes: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 64.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016862, HPA029863" Approved Approved Mitochondria,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 5: Enterocytes - Absorption" "Mitochondria, Cytosol" "HPA016862: AB_1857028, HPA029863: AB_10602893" "unprognostic (1.02e-1)" "unprognostic (1.84e-1)" "unprognostic (2.20e-1)" "unprognostic (3.46e-2)" "unprognostic (5.18e-2)" "unprognostic (3.97e-2)" "unprognostic (1.03e-1)" "unprognostic (5.96e-3)" "unprognostic (4.06e-1)" "unprognostic (1.73e-1)" "unprognostic (1.36e-2)" "unprognostic (2.51e-1)" "unprognostic (3.71e-3)" "unprognostic (3.34e-1)" "unprognostic (5.12e-1)" "unprognostic (4.22e-2)" "unprognostic (3.49e-2)" SLC25A45 ENSG00000162241 "Solute carrier family 25 member 45" Q8N413 11 65375192-65383701 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 33.2" "Cell type enhanced" "Detected in many" "dendritic cells: 50.7;Granulosa cells: 58.3;NK-cells: 64.8;Proximal enterocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 13.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA042495, HPA050821" Uncertain Approved Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Non-specific - Transcription" Cytosol "HPA042495: , HPA050821: AB_2681249" "unprognostic (3.73e-2)" "unprognostic (2.19e-3)" "unprognostic (8.44e-4)" "unprognostic (6.17e-3)" "unprognostic (2.57e-2)" "unprognostic (2.84e-7)" "unprognostic (7.57e-3)" "unprognostic (4.59e-2)" "unprognostic (1.44e-1)" "unprognostic (4.06e-2)" "prognostic favorable (2.83e-4)" "unprognostic (1.96e-1)" "unprognostic (1.08e-2)" "unprognostic (1.45e-1)" "unprognostic (1.54e-1)" "unprognostic (6.18e-2)" "unprognostic (1.43e-1)" SLC25A48 FLJ44862 ENSG00000145832 "Solute carrier family 25 member 48" Q6ZT89 5 135476913-135889770 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.2;kidney: 7.2;skeletal muscle: 6.5" "Cell type enhanced" "Detected in many" "Astrocytes: 29.4;Oocytes: 10.3;Proximal enterocytes: 13.3;Proximal tubular cells: 34.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.9;Rhabdoid: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014674 Uncertain Approved "Intermediate filaments,Actin filaments" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 4 "Intermediate filaments" "Actin filaments" "HPA014674: AB_1859512" "unprognostic (2.09e-1)" "unprognostic (2.24e-1)" "unprognostic (6.34e-2)" "unprognostic (1.21e-1)" "unprognostic (1.37e-2)" "unprognostic (4.71e-2)" "unprognostic (1.96e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-2)" "unprognostic (5.41e-2)" "unprognostic (3.57e-2)" "unprognostic (1.32e-1)" "unprognostic (8.02e-7)" "unprognostic (9.13e-2)" "unprognostic (1.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" SLC25A5 "2F1, ANT2, T2, T3" ENSG00000005022 "Solute carrier family 25 member 5" P05141 X 119468422-119471396 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Chromosome partition, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 2075.7;Proximal enterocytes: 2855.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 640000 "Cluster 33: Non-specific - ATP binding" "Cluster 48: Stomach - Proteolysis" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 5: Enterocytes - Absorption" 1 Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (1.25e-2)" "prognostic favorable (7.35e-4)" "prognostic favorable (7.47e-4)" "unprognostic (1.48e-1)" "unprognostic (4.58e-2)" "unprognostic (1.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.36e-1)" "unprognostic (6.52e-2)" "unprognostic (2.47e-1)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "prognostic favorable (8.06e-6)" "unprognostic (1.41e-1)" "unprognostic (2.65e-1)" "unprognostic (4.36e-2)" "unprognostic (3.03e-1)" SLC26A1 "EDM4, SAT-1" ENSG00000145217 "Solute carrier family 26 member 1" Q9H2B4 4 979073-993440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 16.4" "Cell type enhanced" "Detected in some" "Astrocytes: 5.9;Excitatory neurons: 4.3;Extravillous trophoblasts: 3.8;Hepatocytes: 9.4;Inhibitory neurons: 4.2;Oligodendrocyte precursor cells: 5.2;Proximal enterocytes: 6.6;Proximal tubular cells: 6.3" "Cancer enhanced" "Detected in many" "liver cancer: 5.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 5.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.4" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041654 Uncertain Approved Microtubules NA NA "Cluster 83: Liver - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" Microtubules "HPA041654: AB_10796350" "unprognostic (1.96e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-1)" "unprognostic (4.91e-2)" "unprognostic (1.74e-1)" "unprognostic (2.67e-4)" "unprognostic (5.13e-2)" "unprognostic (5.82e-2)" "unprognostic (2.16e-1)" "unprognostic (3.88e-2)" "unprognostic (1.53e-3)" "unprognostic (2.92e-2)" "prognostic favorable (1.19e-4)" "unprognostic (1.18e-2)" "unprognostic (2.22e-1)" "unprognostic (1.27e-1)" "unprognostic (1.65e-3)" SLC26A6 DKFZp586E1422 ENSG00000225697 "Solute carrier family 26 member 6" Q9BXS9 3 48625723-48635493 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Chloride channel, Ion channel, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 56.0;Intestinal goblet cells: 35.0;Paneth cells: 37.2;Proximal enterocytes: 36.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048363, HPA072381" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Plasma membrane" Cytosol "HPA048363: AB_2680371, HPA072381: " "unprognostic (1.54e-1)" "unprognostic (4.94e-2)" "unprognostic (3.34e-1)" "unprognostic (3.15e-2)" "unprognostic (2.15e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.92e-4)" "unprognostic (2.39e-1)" "unprognostic (2.35e-1)" "unprognostic (2.04e-1)" "unprognostic (4.09e-1)" "unprognostic (9.66e-3)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.58e-2)" SLC27A2 "ACSVL1, FACVL1, FATP2, hFACVL1, HsT17226, VLACS, VLCS" ENSG00000140284 "Solute carrier family 27 member 2" O14975 15 50182196-50236385 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 152.0;liver: 279.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 54.7;Cytotrophoblasts: 259.6;Hepatocytes: 171.6;Proximal enterocytes: 78.3;Proximal tubular cells: 96.0;Syncytiotrophoblasts: 53.8" "Cancer enhanced" "Detected in many" "liver cancer: 49.2" "Region enhanced" "Detected in all" "choroid plexus: 20.1" "Immune cell enriched" "Detected in some" 30 "basophil: 63.7" "Lineage enriched" "Detected in many" 30 "granulocytes: 63.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026089 Enhanced NA NA "Cluster 41: Basophils - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA026089: AB_1857060" "unprognostic (3.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.10e-2)" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (4.06e-3)" "unprognostic (3.33e-1)" "unprognostic (1.89e-1)" "unprognostic (6.38e-3)" "unprognostic (4.83e-2)" "unprognostic (1.82e-1)" "prognostic favorable (7.48e-6)" "unprognostic (5.01e-3)" "unprognostic (4.08e-1)" "unprognostic (1.22e-2)" "prognostic favorable (6.40e-4)" SLC27A4 "ACSVL4, FATP4" ENSG00000167114 "Solute carrier family 27 member 4" Q6P1M0 9 128340527-128361470 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Proximal enterocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007293, CAB009771" Approved Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 80: Non-specific - Endocytosis" "Cluster 45: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "CAB009771: AB_2270540, HPA007293: AB_1857062" "unprognostic (7.25e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-3)" "unprognostic (3.74e-2)" "unprognostic (2.03e-1)" "unprognostic (1.85e-3)" "unprognostic (1.31e-3)" "unprognostic (4.51e-1)" "unprognostic (4.69e-2)" "unprognostic (7.72e-2)" "unprognostic (5.07e-2)" "prognostic favorable (2.61e-5)" "unprognostic (7.29e-3)" "unprognostic (2.11e-1)" "unprognostic (3.45e-2)" "unprognostic (8.01e-3)" SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.7;intestine: 105.9;skeletal muscle: 76.1;testis: 74.1" "Cell type enhanced" "Detected in many" "Early spermatids: 75.6;Paneth cells: 57.9;Proximal enterocytes: 189.6;Spermatocytes: 70.4" "Group enriched" "Detected in many" 6 "glioma: 11.0;renal cancer: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in many" 8 "Leukemia: 40.5;lymphoma: 53.5;Myeloma: 32.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005449, HPA075145" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 4: Testis - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 22: Proximal enterocytes - Digestion" 8 "Plasma membrane" "HPA005449: AB_1078985, HPA075145: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (8.00e-3)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.47e-2)" "unprognostic (5.35e-2)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.19e-3)" "unprognostic (8.61e-2)" SLC35C1 "FLJ11320, FUCT1" ENSG00000181830 "Solute carrier family 35 member C1" Q96A29 11 45804072-45813016 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 46.6;Proximal enterocytes: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064001 Enhanced Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 83: Liver - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "Golgi apparatus" "HPA064001: AB_2685171" "unprognostic (2.62e-2)" "unprognostic (5.16e-2)" "unprognostic (7.82e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (8.22e-2)" "unprognostic (9.40e-2)" "unprognostic (1.56e-2)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "unprognostic (4.09e-2)" "unprognostic (2.73e-1)" "unprognostic (7.68e-2)" "unprognostic (1.83e-3)" "unprognostic (2.18e-1)" "prognostic favorable (3.64e-4)" "unprognostic (2.30e-2)" SLC35D2 "SQV7L, UGTrel8" ENSG00000130958 "Solute carrier family 35 member D2" Q76EJ3 9 96313444-96383711 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 109.0;Proximal enterocytes: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA064047 Approved Supported "Golgi apparatus" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" "Golgi apparatus" "HPA064047: AB_2685182" "unprognostic (3.67e-1)" "unprognostic (5.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.16e-2)" "unprognostic (3.17e-1)" "unprognostic (8.86e-3)" "unprognostic (4.25e-3)" "unprognostic (2.24e-2)" "unprognostic (4.12e-1)" "unprognostic (5.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-2)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (1.44e-1)" SLC36A1 "LYAAT-1, PAT1, TRAMD3" ENSG00000123643 "Solute carrier family 36 member 1" Q7Z2H8 5 151437046-151492379 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 99.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.1;Early spermatids: 79.9;Excitatory neurons: 89.6;Inhibitory neurons: 59.7;Oligodendrocyte precursor cells: 45.8;Proximal enterocytes: 39.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 199.7" "Group enriched" "Detected in many" 4 "basophil: 21.8;classical monocyte: 8.7;neutrophil: 19.7" "Group enriched" "Detected in many" 5 "granulocytes: 21.8;monocytes: 8.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035937 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA035937: AB_10672995" "unprognostic (5.49e-2)" "unprognostic (4.04e-2)" "unprognostic (1.24e-1)" "unprognostic (8.27e-3)" "unprognostic (1.91e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (6.30e-5)" "unprognostic (1.86e-1)" "unprognostic (2.44e-1)" "unprognostic (1.29e-3)" "unprognostic (5.08e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (1.83e-6)" "unprognostic (2.66e-2)" "unprognostic (1.03e-2)" "unprognostic (2.49e-1)" "unprognostic (1.42e-1)" SLC37A4 "G6PT, G6PT1, G6PT2, G6PT3, GSD1b, GSD1c, GSD1d, SPX4" ENSG00000137700 "Solute carrier family 37 member 4" 11 119023751-119030906 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 136.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 175.5;Hepatocytes: 152.1;Proximal enterocytes: 263.6;Proximal tubular cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038939, HPA038940" Enhanced Approved Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "HPA038939: AB_2676279, HPA038940: AB_2676280" "unprognostic (4.77e-2)" "unprognostic (3.49e-1)" "unprognostic (2.08e-2)" "unprognostic (2.35e-2)" "unprognostic (4.70e-2)" "unprognostic (6.95e-3)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (4.08e-2)" "unprognostic (8.27e-3)" "unprognostic (4.72e-2)" "unprognostic (3.89e-1)" "unprognostic (1.98e-1)" "unprognostic (4.04e-2)" "unprognostic (2.60e-1)" "unprognostic (4.34e-2)" "unprognostic (5.39e-2)" SLC3A1 "ATR1, CSNU1, D2H, NBAT, RBAT" ENSG00000138079 "Solute carrier family 3 member 1" Q07837 2 44275458-44321494 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cystinuria, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 132.3;kidney: 624.8;pancreas: 210.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Glandular and luminal cells: 95.7;Oocytes: 164.7;Proximal enterocytes: 219.5;Proximal tubular cells: 221.2" "Cancer enriched" "Detected in many" 7 "renal cancer: 61.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 15.1;Kidney cancer: 17.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038360, HPA071102" Enhanced Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "Nuclear bodies" "HPA038360: AB_2675975, HPA071102: AB_2732171" "unprognostic (1.67e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (6.14e-2)" "unprognostic (9.45e-2)" "unprognostic (2.76e-2)" "unprognostic (1.34e-1)" "unprognostic (3.90e-1)" "unprognostic (8.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.17e-1)" "prognostic favorable (3.67e-7)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (3.77e-1)" "unprognostic (1.58e-4)" SLC44A4 "C6orf29, CTL4, DFNA72, FLJ14491, NG22, TPPT" ENSG00000204385 "Solute carrier family 44 member 4" Q53GD3 6 31863192-31879046 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 128.3;prostate: 80.5;stomach 1: 81.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 304.9;Club cells: 219.1;Distal enterocytes: 526.0;Gastric mucus-secreting cells: 189.2;Intestinal goblet cells: 253.6;Ionocytes: 213.9;Paneth cells: 184.9;Prostatic glandular cells: 320.8;Proximal enterocytes: 256.6" "Cancer enhanced" "Detected in many" "prostate cancer: 222.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 10.7;Gastric cancer: 10.1;prostate cancer: 27.9" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046977, HPA054176" Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "HPA046977: AB_2679887, HPA054176: AB_2682404" "unprognostic (5.84e-2)" "unprognostic (4.90e-2)" "unprognostic (3.86e-3)" "unprognostic (4.85e-3)" "unprognostic (2.75e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.65e-3)" "unprognostic (2.44e-3)" "unprognostic (3.08e-1)" "unprognostic (2.45e-1)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.06e-6)" "unprognostic (1.37e-2)" "unprognostic (2.48e-1)" "unprognostic (4.54e-2)" "prognostic favorable (6.06e-4)" SLC46A3 "DKFZp686A1775, FLJ42613" ENSG00000139508 "Solute carrier family 46 member 3" Q7Z3Q1 13 28700064-28718970 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 73.9;liver: 93.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 48.5;Proximal enterocytes: 113.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039930 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Plasma membrane, Cytosol" "Actin filaments" "HPA039930: AB_10673263" "unprognostic (5.16e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" "unprognostic (3.88e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "prognostic favorable (7.09e-4)" "unprognostic (3.13e-1)" "unprognostic (3.33e-1)" "unprognostic (1.26e-1)" "unprognostic (5.69e-2)" "unprognostic (7.35e-2)" "unprognostic (1.14e-1)" "unprognostic (5.60e-2)" "unprognostic (9.14e-3)" "unprognostic (6.47e-3)" SLC52A3 "bA371L19.1, C20orf54, hRFT2, RFVT3" ENSG00000101276 "Solute carrier family 52 member 3" Q9NQ40 20 760080-776015 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;testis: 39.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 21.4;Cytotrophoblasts: 32.7;Glandular and luminal cells: 22.4;Proximal enterocytes: 41.6;Syncytiotrophoblasts: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049391, HPA059078" Approved NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 "HPA049391: AB_2680743, HPA059078: AB_2732630" "unprognostic (4.53e-2)" "unprognostic (1.11e-1)" "unprognostic (8.60e-2)" "unprognostic (7.84e-2)" "unprognostic (1.29e-1)" "unprognostic (9.03e-3)" "unprognostic (2.12e-3)" "unprognostic (1.43e-3)" "unprognostic (1.15e-2)" "unprognostic (4.36e-2)" "unprognostic (4.39e-3)" "unprognostic (4.82e-2)" "unprognostic (2.04e-3)" "prognostic favorable (5.51e-6)" "unprognostic (3.04e-1)" "unprognostic (2.21e-1)" "unprognostic (1.44e-1)" SLC6A8 "CRT, CRT-1, CRT1, CRTR, CT1" ENSG00000130821 "Solute carrier family 6 member 8" P48029 X 153687926-153696588 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 120.9;Cone photoreceptor cells: 125.7;Distal enterocytes: 164.4;Ionocytes: 118.2;Proximal enterocytes: 196.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Smooth muscle cells, Testis - Sertoli cells" NA NA "Cluster 23: Non-specific - Cellular respiration" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" "unprognostic (5.80e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (9.98e-2)" "unprognostic (1.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.39e-4)" "unprognostic (2.87e-1)" SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 117.6;kidney: 261.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 247.6;Kupffer cells: 327.7;Macrophages: 131.4;monocytes: 264.1;Proximal enterocytes: 399.8;Proximal tubular cells: 264.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 393.7;non-classical monocyte: 447.3" "Lineage enriched" "Detected in many" 5 "monocytes: 447.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 52: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 342.9" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 562.4;Proximal tubular cells: 378.0;Squamous epithelial cells: 344.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 462.6" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" 16 "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" SLX1B "GIYD2, MGC5178" ENSG00000181625 "SLX1 homolog B, structure-specific endonuclease subunit" Q9BQ83 16 29454533-29458219 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Erythroid cells: 1.1;Proximal enterocytes: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA047038 Uncertain Supported Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 2 Nucleoplasm "HPA047038: AB_2679913" "unprognostic (2.93e-1)" "unprognostic (1.11e-1)" "unprognostic (2.16e-2)" "unprognostic (5.12e-2)" "unprognostic (7.05e-2)" "unprognostic (1.78e-1)" "unprognostic (7.20e-2)" "unprognostic (2.72e-2)" "unprognostic (2.35e-3)" "unprognostic (3.63e-1)" "unprognostic (1.22e-1)" "unprognostic (3.64e-2)" "unprognostic (2.51e-7)" "unprognostic (4.84e-2)" "unprognostic (1.96e-1)" "unprognostic (4.44e-1)" "unprognostic (5.25e-3)" SMCO4 "C11orf75, FN5" ENSG00000166002 "Single-pass membrane protein with coiled-coil domains 4" Q9NRQ5 11 93478472-93543391 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 189.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 202.8;Proximal enterocytes: 189.6;Serous glandular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Prostate - Prostate glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041120 Uncertain NA Yes "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 75: Serous glandular cells - Salivary secretion" 51 "HPA041120: AB_2677309" "unprognostic (7.45e-2)" "unprognostic (1.70e-3)" "unprognostic (2.54e-1)" "unprognostic (1.01e-2)" "unprognostic (1.58e-1)" "unprognostic (6.47e-2)" "unprognostic (8.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.43e-1)" "unprognostic (5.51e-1)" "unprognostic (4.23e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (5.81e-7)" "unprognostic (1.61e-1)" "unprognostic (3.05e-1)" "unprognostic (1.55e-2)" "unprognostic (5.01e-2)" SMIM22 CASIMO1 ENSG00000267795 "Small integral membrane protein 22" K7EJ46 16 4788397-4796491 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 188.3;pancreas: 149.9;salivary gland: 142.9;stomach 1: 196.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2064.5;Enteroendocrine cells: 620.1;Intestinal goblet cells: 1141.8;Paneth cells: 999.8;Proximal enterocytes: 1718.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 142.5;colorectal cancer: 173.2" "Breast - Breast glandular cells, Colon - Colon enterocytes, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077331 Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Stomach - Proteolysis" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Nucleoplasm Cytosol "HPA077331: AB_2686834" "unprognostic (6.55e-2)" "unprognostic (4.12e-2)" "unprognostic (4.84e-2)" "unprognostic (3.69e-3)" "unprognostic (7.82e-2)" "unprognostic (3.84e-2)" "unprognostic (4.63e-2)" "unprognostic (2.67e-2)" "unprognostic (6.20e-2)" "unprognostic (3.27e-1)" "unprognostic (2.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.60e-1)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (1.73e-3)" SMIM31 "h.EPR, LINC01207" ENSG00000248771 "Small integral membrane protein 31" A0A1B0GVY4 4 164754064-164803795 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 7.6;intestine: 23.9;prostate: 10.6" "Cell type enhanced" "Detected in some" "Club cells: 38.2;Distal enterocytes: 75.8;Exocrine glandular cells: 45.8;Intestinal goblet cells: 89.1;Paneth cells: 36.1;Prostatic glandular cells: 53.1;Proximal enterocytes: 124.0" "Cancer enhanced" "Detected in many" "prostate cancer: 8.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.1;Gastric cancer: 6.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Secreted - unknown location" "No annotated function" NA NA "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" "unprognostic (2.84e-1)" "unprognostic (1.18e-1)" "unprognostic (2.47e-2)" "unprognostic (1.87e-4)" "unprognostic (2.95e-2)" "unprognostic (1.78e-1)" "unprognostic (4.17e-2)" "unprognostic (4.82e-1)" "unprognostic (9.47e-2)" "unprognostic (5.63e-3)" SMPD3 NSMASE2 ENSG00000103056 "Sphingomyelin phosphodiesterase 3" Q9NY59 16 68358327-68448508 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Lipid metabolism, Sphingolipid metabolism" "Developmental protein, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.8;lymphoid tissue: 50.7" "Cell type enhanced" "Detected in many" "dendritic cells: 221.5;Gastric mucus-secreting cells: 61.3;Horizontal cells: 71.8;Oocytes: 75.0;Proximal enterocytes: 102.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 139.0" "Lineage enriched" "Detected in many" 7 "dendritic cells: 139.0" "Cancer enhanced" "Detected in many" "Leukemia: 11.1;lymphoma: 12.1;Neuroblastoma: 11.2" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Peritubular cells" "Region enhanced" "Detected in all" "basal ganglia: 115.2" "Region enhanced" "Detected in all" "basal ganglia: 83.7" "CAB033885, HPA065535, HPA069383" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" "Endoplasmic reticulum" "CAB033885: AB_1126788, HPA065535: , HPA069383: " "unprognostic (1.21e-1)" "prognostic favorable (7.72e-4)" "unprognostic (5.61e-3)" "prognostic favorable (3.86e-4)" "unprognostic (2.46e-1)" "unprognostic (5.85e-4)" "unprognostic (7.87e-2)" "unprognostic (8.12e-3)" "unprognostic (2.77e-2)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.81e-1)" "unprognostic (1.04e-3)" "unprognostic (5.02e-3)" "unprognostic (2.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.93e-3)" SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 151.1;Distal enterocytes: 169.7;Proximal enterocytes: 334.3;Syncytiotrophoblasts: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 81.1" "Lineage enriched" "Detected in many" 11 "granulocytes: 81.1" "Cancer enhanced" "Detected in all" "prostate cancer: 39.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" Enzyme No No 26000000 "Cluster 32: Basophils - Transcription" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 5: Enterocytes - Absorption" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: AB_10601591" "unprognostic (2.60e-1)" "unprognostic (1.22e-1)" "prognostic favorable (6.11e-4)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (8.30e-3)" "unprognostic (3.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.53e-1)" "unprognostic (1.39e-1)" "unprognostic (7.72e-2)" "unprognostic (2.27e-2)" "unprognostic (3.44e-2)" "unprognostic (8.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" SMPDL3B ASML3B ENSG00000130768 "Sphingomyelin phosphodiesterase acid like 3B" Q92485 1 27935000-27959157 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.4;pancreas: 47.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 36.2;Distal enterocytes: 50.4;Paneth cells: 55.2;Proximal enterocytes: 37.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.3;myeloid DC: 1.3;neutrophil: 1.7" "Group enriched" "Detected in many" 7 "dendritic cells: 1.3;granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA030561 Approved "Golgi apparatus,Cytosol" "Secreted to blood" Immunity NA NA 400000 "Cluster 22: Eosinophils - Transcription" "Cluster 48: Stomach - Proteolysis" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" Cytosol "Golgi apparatus" "HPA030561: AB_10604095" "unprognostic (1.22e-2)" "unprognostic (4.45e-1)" "unprognostic (4.58e-3)" "unprognostic (3.83e-2)" "unprognostic (3.35e-3)" "unprognostic (2.96e-2)" "unprognostic (1.50e-1)" "unprognostic (2.68e-1)" "unprognostic (3.95e-1)" "unprognostic (6.02e-2)" "unprognostic (1.64e-1)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (2.40e-1)" "unprognostic (1.48e-1)" "unprognostic (4.40e-2)" "unprognostic (3.09e-3)" SNX15 ENSG00000110025 "Sorting nexin 15" Q9NRS6 11 65027439-65040572 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal enterocytes: 2.9;Ductal cells: 2.8;Enteroendocrine cells: 3.1;Exocrine glandular cells: 2.7;Pancreatic endocrine cells: 3.4;Paneth cells: 4.5;Proximal enterocytes: 4.0;Schwann cells: 4.4;Undifferentiated cells: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038955 Approved Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 4 "Nucleoli, Cytosol" "Vesicles, Plasma membrane" "HPA038955: AB_10672834" "unprognostic (2.00e-2)" "unprognostic (4.90e-2)" "unprognostic (3.93e-1)" "unprognostic (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (4.06e-3)" "unprognostic (4.45e-3)" "unprognostic (4.74e-2)" "unprognostic (1.09e-1)" "unprognostic (9.55e-2)" "unprognostic (8.93e-3)" "unprognostic (1.79e-2)" "unprognostic (8.84e-2)" "unprognostic (7.86e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.68e-4)" SOWAHB ANKRD56 ENSG00000186212 "Sosondowah ankyrin repeat domain family member B" A6NEL2 4 76894152-76898144 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 18.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 15.6;Hepatocytes: 13.9;Intestinal goblet cells: 9.5;Paneth cells: 9.1;Proximal enterocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 8.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036809, HPA036810" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Nucleoli fibrillar center" "HPA036809: AB_10672479, HPA036810: AB_2675327" "unprognostic (2.05e-1)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (1.87e-2)" "unprognostic (1.02e-2)" "unprognostic (1.02e-2)" "unprognostic (3.28e-2)" "unprognostic (2.21e-1)" "unprognostic (1.51e-2)" "unprognostic (3.06e-1)" "unprognostic (2.85e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.22e-15)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "unprognostic (2.03e-2)" "unprognostic (3.73e-3)" SOWAHD ANKRD58 ENSG00000187808 "Sosondowah ankyrin repeat domain family member D" A6NJG2 X 119758588-119760202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.0;lymphoid tissue: 6.9;testis: 4.8" "Cell type enhanced" "Detected in some" "B-cells: 10.7;Extravillous trophoblasts: 48.3;Hofbauer cells: 17.5;Proximal enterocytes: 10.9;Syncytiotrophoblasts: 11.1" "Cancer enriched" "Detected in many" 6 "testis cancer: 8.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 5.4" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA065955 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA065955: AB_2685586" "unprognostic (1.78e-2)" "unprognostic (9.37e-2)" "unprognostic (3.10e-2)" "unprognostic (8.88e-2)" "unprognostic (1.67e-1)" "unprognostic (4.38e-2)" "unprognostic (2.03e-1)" "unprognostic (7.20e-2)" "unprognostic (3.45e-2)" "unprognostic (6.07e-2)" "unprognostic (5.80e-2)" "unprognostic (2.41e-2)" "unprognostic (1.04e-5)" "unprognostic (5.82e-2)" "unprognostic (3.14e-2)" "unprognostic (9.22e-2)" "unprognostic (3.74e-3)" SPEGNB ENSG00000286095 "SPEG neighbor" A0A087WV53 2 219496131-219498287 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skeletal muscle: 2.0;tongue: 2.1" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 2.9;Late spermatids: 8.2;Pancreatic endocrine cells: 17.0;Proximal enterocytes: 4.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.9" "Not detected" "Not detected" NA NA "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" SPINT1 "HAI, HAI-1, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 248.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1211.1;Ductal cells: 415.0;Proximal enterocytes: 467.2;Syncytiotrophoblasts: 1698.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" "Enzyme inhibitor" NA NA 7400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 48: Stomach - Proteolysis" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" SPSB1 SSB-1 ENSG00000171621 "SplA/ryanodine receptor domain and SOCS box containing 1" Q96BD6 1 9292894-9369532 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 83.4;Proximal enterocytes: 86.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 62: Connective tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 53: Fibroblasts - ECM organization" 19 "unprognostic (5.23e-2)" "unprognostic (8.91e-2)" "unprognostic (1.56e-1)" "unprognostic (2.85e-1)" "unprognostic (4.18e-2)" "unprognostic (2.88e-1)" "unprognostic (2.02e-2)" "unprognostic (1.24e-1)" "unprognostic (3.84e-2)" "unprognostic (2.54e-2)" "unprognostic (6.86e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.08e-6)" "unprognostic (3.95e-2)" "unprognostic (3.49e-1)" "unprognostic (1.35e-2)" "unprognostic (2.24e-2)" SRI ENSG00000075142 Sorcin P30626 7 88205115-88226993 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 546.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1616.4;Extravillous trophoblasts: 1763.8;Paneth cells: 1637.8;Proximal enterocytes: 1304.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019004, HPA073666" Enhanced Approved Nucleoplasm,Cytosol No No 1100000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 6 "Nucleoplasm, Cytosol" "HPA019004: AB_2670006, HPA073666: AB_2686623" "unprognostic (1.86e-2)" "unprognostic (2.31e-3)" "unprognostic (1.89e-2)" "unprognostic (1.73e-2)" "unprognostic (1.31e-1)" "unprognostic (4.42e-3)" "unprognostic (1.24e-3)" "prognostic favorable (3.08e-4)" "unprognostic (9.87e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.36e-1)" "unprognostic (2.10e-2)" "unprognostic (1.29e-2)" "unprognostic (9.87e-2)" "unprognostic (8.44e-2)" "unprognostic (3.14e-3)" SSTR1 ENSG00000139874 "Somatostatin receptor 1" P30872 14 38207904-38213067 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.2;intestine: 13.4;stomach 1: 21.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 9.0;Enteroendocrine cells: 25.1;Gastric mucus-secreting cells: 18.3;Oligodendrocyte precursor cells: 22.6;Paneth cells: 11.1;Proximal enterocytes: 10.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003207, HPA031506" Approved Uncertain Vesicles NA NA "Cluster 25: Small intestine - Absorption" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 Vesicles "HPA003207: , HPA031506: AB_2673913" "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-1)" "unprognostic (2.50e-3)" "unprognostic (4.34e-2)" "unprognostic (9.90e-2)" "unprognostic (3.66e-3)" "unprognostic (1.91e-1)" "unprognostic (6.16e-3)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (9.19e-2)" "prognostic favorable (4.28e-4)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" "unprognostic (3.28e-2)" SSUH2 "C3orf32, fls485, ssu-2" ENSG00000125046 "Ssu-2 homolog" Q9Y2M2 3 8619386-8745040 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.4;testis: 5.4" "Cell type enhanced" "Detected in some" "Adipocytes: 9.0;Early spermatids: 59.4;Late spermatids: 47.2;Proximal enterocytes: 13.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.8" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA049777 Approved NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 18: Liver cancer - Metabolism" "Cluster 11: Late spermatids - Unknown function" "HPA049777: AB_2680876" "unprognostic (2.49e-1)" "unprognostic (7.62e-2)" "unprognostic (9.65e-2)" "unprognostic (1.68e-1)" "unprognostic (2.46e-1)" "unprognostic (8.86e-2)" "unprognostic (1.46e-3)" "unprognostic (9.79e-2)" "unprognostic (1.53e-1)" "unprognostic (4.09e-1)" "unprognostic (7.97e-3)" "unprognostic (1.52e-1)" "unprognostic (3.15e-3)" "unprognostic (1.31e-1)" "unprognostic (3.65e-2)" "unprognostic (4.96e-2)" "unprognostic (7.50e-2)" ST14 "CAP3, HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 140.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 375.6;Intestinal goblet cells: 175.1;Paneth cells: 164.2;Proximal enterocytes: 201.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 19.4" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Colon enterocytes, Heart muscle - Macrophages, Pancreas - Ductal cells, Skeletal muscle - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "Nucleoplasm, Vesicles" "HPA047014: AB_2679902, HPA056258: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" STAP2 "BKS, STAP-2" ENSG00000178078 "Signal transducing adaptor family member 2" Q9UGK3 19 4324043-4342786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 166.6;Distal enterocytes: 335.5;Paneth cells: 316.8;Proximal enterocytes: 434.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 8.0" "Group enriched" "Detected in many" 6 "dendritic cells: 2.2;NK-cells: 8.0;T-cells: 2.5" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Pancreas - Ductal cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Region enriched" "Detected in many" 13 "cerebellum: 20.5" "Low region specificity" "Detected in some" "HPA002375, HPA027761" Approved NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 9 "HPA002375: AB_1078285, HPA027761: AB_1845364" "unprognostic (1.42e-1)" "prognostic favorable (2.76e-4)" "unprognostic (3.52e-1)" "prognostic favorable (3.03e-5)" "unprognostic (4.35e-2)" "unprognostic (9.35e-3)" "unprognostic (4.52e-1)" "unprognostic (7.81e-2)" "unprognostic (3.43e-1)" "unprognostic (2.00e-2)" "unprognostic (1.93e-2)" "unprognostic (9.05e-2)" "unprognostic (1.43e-3)" "unprognostic (1.38e-2)" "unprognostic (1.72e-1)" "unprognostic (3.00e-2)" "prognostic favorable (4.13e-4)" STBD1 "FLJ41801, GENX-3414" ENSG00000118804 "Starch binding domain 1" O95210 4 76306733-76311130 "Plasma proteins, Predicted intracellular proteins, Transporters" "Autophagy, Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 126.4;skeletal muscle: 239.8;tongue: 148.6" "Cell type enhanced" "Detected in some" "Ductal cells: 5.2;Glandular and luminal cells: 3.9;Plasma cells: 5.0;Proximal enterocytes: 10.5;Skeletal myocytes: 4.9;Smooth muscle cells: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011952, HPA012849" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Smooth muscle cells - Muscle contraction" 5 "Endoplasmic reticulum" "HPA011952: AB_1847461, HPA012849: AB_1847460" "unprognostic (1.46e-1)" "unprognostic (1.02e-3)" "unprognostic (4.29e-2)" "unprognostic (1.95e-1)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (1.35e-2)" "unprognostic (6.84e-2)" "unprognostic (3.06e-1)" "unprognostic (1.03e-1)" "unprognostic (4.96e-3)" "unprognostic (4.42e-2)" "unprognostic (3.52e-2)" "unprognostic (2.93e-1)" "unprognostic (2.00e-1)" "unprognostic (2.84e-1)" "unprognostic (5.74e-2)" STRADB "ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK" ENSG00000082146 "STE20 related adaptor beta" Q9C0K7 2 201387858-201480846 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 201.2;Hepatocytes: 107.6;Proximal enterocytes: 120.9;Proximal tubular cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026549, HPA028520" Approved Uncertain Aggresome,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 1: Erythroid cells - Oxygen transport" 2 Cytosol Aggresome "HPA026549: AB_1844779, HPA028520: AB_10604100" "unprognostic (6.34e-2)" "unprognostic (2.48e-1)" "unprognostic (2.63e-1)" "unprognostic (3.56e-3)" "unprognostic (4.04e-2)" "unprognostic (7.64e-2)" "unprognostic (1.35e-1)" "unprognostic (1.58e-1)" "unprognostic (2.63e-3)" "unprognostic (2.65e-2)" "unprognostic (6.21e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.08e-1)" "unprognostic (7.83e-2)" "prognostic favorable (4.45e-4)" "unprognostic (4.93e-2)" STX19 MGC21382 ENSG00000178750 "Syntaxin 19" Q8N4C7 3 94014365-94028597 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 16.0;intestine: 13.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.6;Glandular and luminal cells: 18.2;Intestinal goblet cells: 36.2;Paneth cells: 35.4;Proximal enterocytes: 19.8;Rod photoreceptor cells: 17.5" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 5.9;prostate cancer: 5.4" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030604 Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 16: Intestinal goblet cells - Mucin production" 16 "Intermediate filaments" Cytosol "HPA030604: AB_10601268" "unprognostic (7.35e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-1)" "unprognostic (5.17e-2)" "unprognostic (2.35e-1)" "unprognostic (1.13e-2)" "unprognostic (1.92e-1)" "unprognostic (1.21e-1)" "unprognostic (9.42e-2)" "unprognostic (9.04e-2)" "unprognostic (1.29e-2)" "unprognostic (4.32e-2)" "unprognostic (7.00e-3)" "unprognostic (1.19e-2)" "unprognostic (1.96e-1)" "unprognostic (2.12e-1)" "unprognostic (4.87e-3)" SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 533.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 771.4;Proximal enterocytes: 644.2;Proximal tubular cells: 3002.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" Enzyme NA NA 350000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" SULT1A1 "P-PST, STP, STP1" ENSG00000196502 "Sulfotransferase family 1A member 1" P50225 16 28605196-28614279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 221.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 297.1;Hepatocytes: 252.1;Proximal enterocytes: 949.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 245.3;intermediate monocyte: 201.2;myeloid DC: 112.3;neutrophil: 227.1;non-classical monocyte: 114.4" "Group enriched" "Detected in all" 24 "dendritic cells: 112.3;granulocytes: 227.1;monocytes: 245.3" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "HPA049500, HPA051051" Supported NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 1 "HPA049500: AB_2680796, HPA051051: AB_2681327" "unprognostic (2.57e-2)" "unprognostic (2.80e-2)" "unprognostic (8.40e-2)" "unprognostic (1.30e-1)" "unprognostic (5.60e-3)" "unprognostic (7.63e-2)" "unprognostic (4.17e-2)" "prognostic favorable (7.02e-4)" "unprognostic (1.30e-1)" "unprognostic (2.40e-1)" "unprognostic (6.71e-2)" "unprognostic (2.07e-1)" "unprognostic (3.70e-3)" "unprognostic (1.49e-1)" "unprognostic (4.10e-2)" "unprognostic (7.39e-2)" "unprognostic (1.89e-2)" SULT1B1 ST1B2 ENSG00000173597 "Sulfotransferase family 1B member 1" O43704 4 69721167-69787961 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 96.3;stomach 1: 43.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 295.5;Enteroendocrine cells: 53.8;Gastric mucus-secreting cells: 56.0;Paneth cells: 112.2;Proximal enterocytes: 223.7" "Group enriched" "Detected in some" 11 "colorectal cancer: 7.6;liver cancer: 2.6;pancreatic cancer: 5.5;stomach cancer: 5.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 10.6;neutrophil: 32.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 32.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Colon - Colon enterocytes, Prostate - Macrophages, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002107 Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 9: Non-specific - Receptor signaling" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 5: Enterocytes - Absorption" 7 "Golgi apparatus" Nucleoplasm "HPA002107: AB_2666542" "unprognostic (9.58e-2)" "unprognostic (4.05e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (2.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "unprognostic (4.77e-2)" "unprognostic (5.14e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-1)" "unprognostic (1.15e-3)" "unprognostic (1.89e-1)" "unprognostic (1.06e-2)" "unprognostic (6.93e-2)" "unprognostic (5.46e-2)" SULT1E1 "EST, STE" ENSG00000109193 "Sulfotransferase family 1E member 1" P49888 4 69841212-69860145 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 26.7;liver: 36.0;skin 1: 18.7;vagina: 29.5" "Cell type enhanced" "Detected in some" "Ciliated cells: 13.5;Glandular and luminal cells: 30.1;Hepatocytes: 46.5;Paneth cells: 54.8;Proximal enterocytes: 18.7;Salivary duct cells: 16.4;Undifferentiated cells: 12.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "choroid plexus: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 4.4" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028213, HPA028728, CAB047344" Enhanced Uncertain "Nuclear membrane,Cytosol" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "Nuclear membrane, Cytosol" "CAB047344: , HPA028213: AB_10599848, HPA028728: AB_10601894" "unprognostic (5.60e-2)" "prognostic favorable (4.06e-4)" "unprognostic (2.48e-1)" "unprognostic (1.07e-3)" "unprognostic (2.42e-1)" "unprognostic (1.95e-1)" "unprognostic (1.70e-1)" "unprognostic (1.72e-1)" "unprognostic (1.41e-1)" "unprognostic (2.89e-1)" "unprognostic (3.22e-3)" "unprognostic (8.62e-2)" "unprognostic (6.48e-5)" "unprognostic (2.48e-1)" "unprognostic (4.11e-2)" "unprognostic (5.55e-2)" TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 67.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 101.6;Proximal enterocytes: 84.9;Proximal tubular cells: 94.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 15 Mitochondria "HPA021626: AB_1846148, HPA021643: AB_1846149, HPA024294: AB_1846150" "unprognostic (1.26e-1)" "unprognostic (2.92e-2)" "unprognostic (4.55e-3)" "unprognostic (9.82e-2)" "unprognostic (1.30e-1)" "unprognostic (9.30e-3)" "unprognostic (2.83e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (7.38e-2)" "prognostic favorable (3.73e-4)" "unprognostic (1.35e-1)" "unprognostic (4.12e-3)" "unprognostic (5.21e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" TAPBPL "FLJ10143, TAPBP-R, TAPBPR" ENSG00000139192 "TAP binding protein like" Q9BX59 12 6451690-6466517 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Plasma cells: 84.1;Proximal enterocytes: 77.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039545 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 77: Plasma cells - Protein processing" 8 "HPA039545: AB_10673360" "prognostic favorable (1.98e-4)" "unprognostic (3.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.30e-1)" "unprognostic (1.32e-1)" "unprognostic (4.61e-2)" "unprognostic (1.91e-1)" "unprognostic (7.64e-2)" "unprognostic (4.07e-2)" "unprognostic (3.18e-1)" "unprognostic (5.66e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.04e-5)" "unprognostic (3.53e-2)" "unprognostic (7.61e-2)" "unprognostic (6.28e-2)" "prognostic favorable (7.86e-4)" TDP2 TTRAP ENSG00000111802 "Tyrosyl-DNA phosphodiesterase 2" O95551 6 24649979-24666930 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" "Hydrolase, Nuclease" "Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 178.2" "Cell type enhanced" "Detected in all" "Distal enterocytes: 604.3;Paneth cells: 462.3;Proximal enterocytes: 607.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 75.8;neutrophil: 229.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 229.6" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB073398, HPA074011" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Enzyme No No "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" 6 "Nucleoplasm, Nuclear bodies" "CAB073398: , HPA074011: AB_2686651" "unprognostic (2.46e-2)" "unprognostic (2.10e-3)" "unprognostic (1.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.58e-1)" "unprognostic (4.66e-3)" "unprognostic (4.13e-3)" "unprognostic (3.24e-1)" "unprognostic (5.78e-3)" "prognostic favorable (2.53e-7)" "unprognostic (1.20e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (1.40e-2)" "unprognostic (1.42e-1)" "unprognostic (9.70e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.47e-5)" TEAD4 "EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1" ENSG00000197905 "TEA domain transcription factor 4" Q15561 12 2959330-3040676 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 122.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 34.3;Cytotrophoblasts: 53.0;Exocrine glandular cells: 29.1;Proximal enterocytes: 38.7" "Cancer enriched" "Detected in all" 5 "testis cancer: 78.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Prostate - Endothelial cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Region enriched" "Detected in single" 5 "cerebellum: 3.1" "Low region specificity" "Detected in all" HPA056896 Uncertain Supported Nucleoplasm NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 12: Non-specific - Vasculature" "Cluster 38: Non-specific - Transcription" "Cluster 24: Cytotrophoblasts - Mitochondria" 30 Nucleoplasm "HPA056896: AB_2683268" "unprognostic (3.68e-1)" "unprognostic (3.98e-1)" "unprognostic (2.17e-1)" "unprognostic (1.55e-3)" "unprognostic (1.33e-1)" "unprognostic (3.68e-1)" "unprognostic (9.20e-3)" "unprognostic (2.21e-3)" "unprognostic (3.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.50e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (9.78e-9)" "unprognostic (5.05e-3)" "unprognostic (8.43e-2)" "unprognostic (2.42e-2)" "unprognostic (1.23e-3)" TFAP4 "AP-4, bHLHc41" ENSG00000090447 "Transcription factor AP-4" Q01664 16 4257186-4273075 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 26.1;Proximal enterocytes: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001912 Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 66: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" 13 "Nucleoplasm, Mitochondria" "HPA001912: AB_1080251" "unprognostic (1.61e-2)" "unprognostic (1.36e-1)" "unprognostic (5.10e-2)" "unprognostic (4.42e-3)" "unprognostic (8.61e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (8.05e-2)" "unprognostic (8.97e-2)" "unprognostic (4.60e-1)" "unprognostic (5.75e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (4.31e-6)" "unprognostic (1.08e-2)" "unprognostic (3.25e-1)" "unprognostic (2.39e-2)" "unprognostic (1.30e-1)" THOP1 ENSG00000172009 "Thimet oligopeptidase 1" P52888 19 2785503-2815807 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 158.1;Paneth cells: 142.6;Proximal enterocytes: 302.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025497, HPA035262" Uncertain Supported Cytosol NA NA 2000000 "Cluster 14: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 5: Enterocytes - Absorption" 1 Cytosol "CAB025497: , HPA035262: AB_2674541" "unprognostic (1.52e-2)" "unprognostic (1.73e-3)" "unprognostic (7.94e-2)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (2.16e-2)" "unprognostic (9.35e-2)" "unprognostic (1.19e-1)" "unprognostic (4.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-3)" "unprognostic (3.00e-2)" "unprognostic (1.39e-1)" "prognostic favorable (5.90e-4)" "unprognostic (1.27e-1)" "unprognostic (2.64e-1)" "unprognostic (5.37e-2)" TIGD3 ENSG00000173825 "Tigger transposable element derived 3" Q6B0B8 11 65354751-65357613 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;testis: 4.9" "Cell type enhanced" "Detected in many" "dendritic cells: 20.2;Granulosa cells: 10.1;Proximal enterocytes: 10.2;Spermatocytes: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 7.8;eosinophil: 10.9;neutrophil: 17.5" "Lineage enriched" "Detected in many" 11 "granulocytes: 17.5" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA040016 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Spermatocytes & Spermatogonia - Spermatogenesis" 1 "Nucleoplasm, Nuclear membrane" "HPA040016: AB_10805600" "unprognostic (1.33e-1)" "unprognostic (1.81e-2)" "unprognostic (1.88e-2)" "unprognostic (1.60e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-3)" "unprognostic (9.04e-4)" "unprognostic (1.48e-4)" "unprognostic (6.97e-2)" "unprognostic (1.47e-1)" "unprognostic (3.94e-3)" "unprognostic (7.40e-2)" "unprognostic (3.20e-2)" "unprognostic (7.55e-3)" "unprognostic (1.01e-1)" "unprognostic (2.11e-1)" "unprognostic (1.75e-3)" TJP3 ZO-3 ENSG00000105289 "Tight junction protein 3" O95049 19 3708362-3750813 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8;stomach 1: 26.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 198.8;Early spermatids: 585.1;Paneth cells: 108.7;Proximal enterocytes: 127.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "choroid plexus: 16.2" "Group enriched" "Detected in many" 5 "gdT-cell: 1.2;MAIT T-cell: 3.9;memory CD4 T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD4 T-cell: 3.3;naive CD8 T-cell: 1.2;T-reg: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB013244, HPA046863, HPA053337" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" 1 "Nucleoplasm, Cell Junctions" "Plasma membrane" "CAB013244: AB_2533257, HPA046863: AB_2679845, HPA053337: AB_2682118" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.83e-6)" "unprognostic (2.78e-1)" "prognostic favorable (9.52e-4)" "unprognostic (1.30e-1)" "unprognostic (1.25e-1)" "unprognostic (2.52e-1)" "unprognostic (6.52e-2)" "unprognostic (2.15e-2)" "unprognostic (1.78e-1)" "prognostic favorable (9.36e-8)" "unprognostic (8.58e-3)" "unprognostic (5.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.62e-3)" TLCD2 ENSG00000185561 "TLC domain containing 2" A6NGC4 17 1702816-1710377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 76.5;Distal enterocytes: 85.6;Proximal enterocytes: 64.8;Skeletal myocytes: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.3;neutrophil: 1.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Sebaceous gland cells" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 18.7" HPA046063 Uncertain Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA046063: AB_2679520" "unprognostic (1.78e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (4.04e-2)" "unprognostic (7.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.36e-5)" "unprognostic (3.77e-2)" "unprognostic (2.82e-1)" "unprognostic (7.79e-2)" "unprognostic (4.44e-2)" TLDC2 "C20orf118, dJ132F21.2" ENSG00000101342 "TBC/LysM-associated domain containing 2" A0PJX2 20 36876121-36894235 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 13.5;Enteroendocrine cells: 9.9;granulocytes: 9.3;Paneth cells: 16.6;Proximal enterocytes: 19.9;Undifferentiated cells: 5.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 4.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.9" "Region enriched" "Detected in many" 4 "cerebellum: 5.7" "Low region specificity" "Detected in all" HPA047468 Enhanced NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "HPA047468: AB_2680059" "unprognostic (9.06e-3)" "unprognostic (3.35e-4)" "unprognostic (4.60e-1)" "unprognostic (1.07e-3)" "unprognostic (1.40e-1)" "unprognostic (6.51e-3)" "unprognostic (1.09e-3)" "unprognostic (5.55e-2)" "unprognostic (1.62e-1)" "unprognostic (2.82e-2)" "unprognostic (3.67e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (9.97e-5)" "unprognostic (7.25e-2)" "unprognostic (6.20e-2)" "unprognostic (5.59e-2)" "unprognostic (4.87e-2)" TMC4 ENSG00000167608 "Transmembrane channel like 4" 19 54160108-54173250 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 44.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 114.5;Distal enterocytes: 144.1;Proximal enterocytes: 214.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA048635 Approved Approved Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Respiratory epithelial cells - Unknown function" Vesicles "HPA048635: AB_2680470" "unprognostic (7.55e-2)" "unprognostic (1.66e-1)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.82e-2)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-3)" "unprognostic (7.59e-2)" "unprognostic (3.09e-1)" "prognostic favorable (1.54e-8)" "unprognostic (6.70e-2)" "unprognostic (2.48e-1)" "unprognostic (8.94e-2)" "unprognostic (1.79e-2)" TMC5 FLJ13593 ENSG00000103534 "Transmembrane channel like 5" Q6UXY8 16 19410496-19499113 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 51.9;stomach 1: 44.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 265.3;Exocrine glandular cells: 179.4;Gastric mucus-secreting cells: 181.6;Ionocytes: 356.7;Oocytes: 204.4;Proximal enterocytes: 351.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 6 "choroid plexus: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 32.0;Gastric cancer: 35.0" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040810, HPA042037" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA040810: AB_10795627, HPA042037: AB_10804126" "unprognostic (2.47e-2)" "unprognostic (3.68e-1)" "unprognostic (3.50e-2)" "unprognostic (2.74e-3)" "unprognostic (1.01e-1)" "unprognostic (3.64e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "unprognostic (9.74e-2)" "unprognostic (3.27e-2)" "unprognostic (3.71e-1)" "unprognostic (2.28e-2)" "unprognostic (2.69e-1)" "unprognostic (7.88e-2)" "unprognostic (8.88e-3)" "unprognostic (1.75e-1)" TMEM106C MGC5576 ENSG00000134291 "Transmembrane protein 106C" Q9BVX2 12 47963569-47968878 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 219.5;Muller glia cells: 267.9;Proximal enterocytes: 388.4;Undifferentiated cells: 227.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047204 Enhanced NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 53: Non-specific - Glycosylation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" 37 "HPA047204: AB_2679982" "unprognostic (1.63e-2)" "unprognostic (5.84e-2)" "unprognostic (1.56e-2)" "unprognostic (2.40e-1)" "unprognostic (3.13e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.27e-8)" "unprognostic (1.05e-1)" "unprognostic (1.90e-2)" "unprognostic (1.52e-3)" "unprognostic (3.60e-1)" "unprognostic (7.29e-2)" "prognostic favorable (4.62e-4)" "unprognostic (1.12e-2)" "unprognostic (1.16e-1)" "unprognostic (2.57e-2)" "unprognostic (1.83e-1)" TMEM120A "NET29, TACAN, TMPIT" ENSG00000189077 "Transmembrane protein 120A" Q9BXJ8 7 75986831-75994656 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 241.8;Late spermatids: 1002.8;Proximal enterocytes: 421.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 223.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 36: Late spermatids - Unknown function" 21 "unprognostic (1.78e-2)" "unprognostic (3.35e-2)" "unprognostic (1.71e-2)" "unprognostic (4.03e-2)" "unprognostic (1.00e-1)" "unprognostic (1.99e-1)" "unprognostic (3.26e-1)" "unprognostic (2.75e-3)" "unprognostic (6.16e-2)" "unprognostic (1.59e-2)" "unprognostic (1.10e-1)" "unprognostic (6.31e-2)" "unprognostic (1.02e-1)" "unprognostic (6.58e-2)" "unprognostic (6.61e-2)" "unprognostic (1.71e-1)" "unprognostic (5.15e-2)" TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 73.4;pancreas: 87.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.1;Alveolar cells type 2: 178.6;Distal enterocytes: 75.1;Proximal enterocytes: 169.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" "Midbody, Cytosol" "HPA015796: AB_1858081" "unprognostic (2.53e-3)" "unprognostic (8.70e-2)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (3.14e-2)" "unprognostic (8.50e-2)" "unprognostic (8.37e-3)" "prognostic favorable (5.11e-5)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (7.76e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (4.04e-1)" "unprognostic (5.16e-2)" TMEM139 FLJ90586 ENSG00000178826 "Transmembrane protein 139" Q8IV31 7 143279957-143288048 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.9;kidney: 31.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 37.3;Collecting duct cells: 50.6;Distal enterocytes: 44.5;Ductal cells: 43.3;Proximal enterocytes: 85.8;Proximal tubular cells: 86.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036982, HPA036983" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" 35 "Plasma membrane" "Focal adhesion sites" "HPA036982: AB_2675413, HPA036983: AB_10672275" "unprognostic (2.58e-1)" "unprognostic (4.38e-1)" "unprognostic (6.62e-3)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (2.16e-3)" "unprognostic (2.83e-2)" "unprognostic (4.90e-2)" "unprognostic (1.60e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (2.89e-1)" "prognostic favorable (3.05e-5)" "unprognostic (1.73e-1)" "unprognostic (1.42e-2)" "unprognostic (2.83e-2)" "unprognostic (9.08e-3)" TMEM141 MGC14141 ENSG00000244187 "Transmembrane protein 141" Q96I45 9 136791344-136793317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 802.8;Paneth cells: 667.8;Proximal enterocytes: 646.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014615, HPA050244" Approved Supported "Cell Junctions,Mitochondria" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 3 Mitochondria "Cell Junctions" "HPA014615: AB_2204756, HPA050244: AB_2681061" "unprognostic (2.05e-1)" "unprognostic (1.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (2.00e-1)" "unprognostic (8.53e-3)" "unprognostic (1.52e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.24e-1)" "unprognostic (8.45e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.49e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" TMEM176A "HCA112, MS4B1" ENSG00000002933 "Transmembrane protein 176A" Q96HP8 7 150800403-150805118 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 363.1;liver: 1133.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 1025.8;Paneth cells: 727.3;Proximal enterocytes: 1314.4;Proximal tubular cells: 874.9" "Cancer enhanced" "Detected in all" "liver cancer: 210.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 146.6;intermediate monocyte: 98.5" "Lineage enriched" "Detected in many" 5 "monocytes: 146.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 42.1;Gastric cancer: 31.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008770 Approved Approved Mitochondria NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 22: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 12 Mitochondria "HPA008770: AB_2256120" "unprognostic (4.70e-2)" "unprognostic (7.71e-2)" "unprognostic (5.71e-3)" "unprognostic (6.09e-2)" "unprognostic (3.96e-3)" "unprognostic (1.44e-2)" "unprognostic (2.51e-1)" "unprognostic (2.32e-1)" "unprognostic (4.19e-2)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (4.37e-2)" "unprognostic (4.79e-1)" "unprognostic (1.23e-2)" "unprognostic (1.98e-2)" "unprognostic (2.64e-1)" "unprognostic (4.91e-2)" TMEM184A "MGC9712, SDMG1" ENSG00000164855 "Transmembrane protein 184A" Q6ZMB5 7 1542235-1560821 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 91.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 54.1;Intestinal goblet cells: 37.4;Proximal enterocytes: 53.1;Suprabasal keratinocytes: 54.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 72.4" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA053790, HPA071312" Uncertain Uncertain Nucleoplasm NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 59: Suprabasal keratinocytes - Cornification" Nucleoplasm "HPA053790: AB_2682263, HPA071312: AB_2686387" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (2.38e-1)" "unprognostic (4.41e-3)" "unprognostic (1.07e-1)" "unprognostic (2.36e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-1)" "unprognostic (1.31e-1)" "unprognostic (6.70e-2)" "unprognostic (2.77e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.94e-4)" "unprognostic (5.47e-2)" TMEM198 "MGC99813, TMEM198A" ENSG00000188760 "Transmembrane protein 198" Q66K66 2 219543663-219550595 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 13.9;Horizontal cells: 18.3;Muller glia cells: 11.5;Proximal enterocytes: 11.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042385, HPA062897" Enhanced Approved Vesicles NA NA "Cluster 66: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" Vesicles "HPA042385: AB_2677972, HPA062897: " "unprognostic (2.59e-2)" "unprognostic (8.51e-2)" "unprognostic (5.97e-3)" "unprognostic (2.77e-1)" "unprognostic (4.43e-2)" "unprognostic (8.09e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (4.28e-1)" "unprognostic (2.06e-1)" "prognostic favorable (6.89e-4)" "unprognostic (6.39e-2)" "unprognostic (7.91e-3)" "unprognostic (3.41e-3)" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" TMEM219 IGFBP-3R ENSG00000149932 "Transmembrane protein 219" Q86XT9 16 29940885-29973050 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 631.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059185 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 7: Non-specific - Ribosome" "Cluster 54: Non-specific - Transcription" "Cluster 22: Proximal enterocytes - Digestion" 2 "HPA059185: AB_2683941" "unprognostic (4.13e-2)" "unprognostic (1.94e-3)" "unprognostic (1.51e-1)" "prognostic favorable (5.79e-4)" "unprognostic (2.62e-1)" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (9.83e-2)" "unprognostic (8.53e-2)" "unprognostic (1.71e-1)" "unprognostic (4.18e-1)" "unprognostic (1.19e-1)" "unprognostic (3.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (1.28e-3)" TMEM220 ENSG00000187824 "Transmembrane protein 220" Q6QAJ8 17 10699015-10730023 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 100.5" "Cell type enhanced" "Detected in many" "Early spermatids: 123.1;Hepatocytes: 184.2;Proximal enterocytes: 559.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 21.2" "Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 2 "unprognostic (1.71e-2)" "unprognostic (4.60e-2)" "unprognostic (6.31e-3)" "unprognostic (4.04e-3)" "unprognostic (1.05e-3)" "unprognostic (1.84e-4)" "prognostic favorable (2.23e-5)" "unprognostic (4.58e-2)" "unprognostic (4.96e-3)" "unprognostic (2.81e-1)" "prognostic favorable (1.72e-4)" "unprognostic (2.97e-1)" "unprognostic (4.34e-3)" "unprognostic (2.25e-1)" "unprognostic (2.63e-2)" "unprognostic (7.80e-3)" "unprognostic (5.97e-2)" TMEM229A ENSG00000234224 "Transmembrane protein 229A" B2RXF0 7 124030921-124033067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.6;intestine: 8.2;testis: 5.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.0;Cytotrophoblasts: 2.8;Horizontal cells: 5.0;Oligodendrocytes: 10.6;Proximal enterocytes: 9.9;Sertoli cells: 2.7" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Bone cancer: 9.8;Neuroblastoma: 11.4" "Colon - Colon enteroendocrine cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056391 Uncertain Approved "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane" "HPA056391: AB_2683114" "unprognostic (2.52e-2)" "unprognostic (3.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.50e-1)" "unprognostic (2.89e-2)" "unprognostic (8.21e-2)" "unprognostic (4.74e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" TMEM229B "C14orf83, FLJ33387" ENSG00000198133 "Transmembrane protein 229B" Q8NBD8 14 67447084-67533739 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.4" "Cell type enhanced" "Detected in many" "Late spermatids: 28.1;Oligodendrocyte precursor cells: 17.9;Proximal enterocytes: 11.9" "Cancer enhanced" "Detected in all" "melanoma: 12.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 19.3" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046562 Approved NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Late spermatids - Unknown function" 34 "HPA046562: AB_10960265" "prognostic favorable (5.38e-4)" "unprognostic (6.55e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.21e-5)" "unprognostic (7.37e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (2.01e-1)" "unprognostic (2.01e-2)" "unprognostic (1.12e-1)" "unprognostic (2.76e-3)" "unprognostic (1.95e-2)" "unprognostic (5.18e-1)" "unprognostic (8.66e-2)" "unprognostic (1.22e-1)" "unprognostic (8.20e-2)" "prognostic favorable (1.79e-5)" TMEM25 FLJ14399 ENSG00000149582 "Transmembrane protein 25" Q86YD3 11 118531041-118547280 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 76.5;Proximal enterocytes: 138.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012163, HPA051562" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" "No annotated function" NA NA 6900000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 80: Non-specific - Endocytosis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 "Golgi apparatus, Vesicles" "HPA012163: AB_1858112, HPA051562: AB_2681535" "unprognostic (1.53e-2)" "unprognostic (7.18e-2)" "unprognostic (2.43e-1)" "unprognostic (6.69e-2)" "unprognostic (3.61e-1)" "unprognostic (6.50e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-3)" "unprognostic (1.58e-1)" "unprognostic (3.42e-1)" "unprognostic (1.66e-2)" "unprognostic (8.19e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.15e-1)" "unprognostic (2.51e-1)" "unprognostic (1.26e-1)" "unprognostic (7.01e-2)" TMEM256 "C17orf61, MGC40107" ENSG00000205544 "Transmembrane protein 256" Q8N2U0 17 7402975-7404097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 607.9;Proximal enterocytes: 977.5;Proximal tubular cells: 818.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062732 Approved Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "HPA062732: AB_2684852" "unprognostic (3.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (2.77e-2)" "unprognostic (1.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.69e-2)" "unprognostic (5.73e-2)" "unprognostic (7.45e-2)" "unprognostic (2.12e-2)" "unprognostic (3.22e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (1.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.19e-2)" TMEM37 "PR, PR1" ENSG00000171227 "Transmembrane protein 37" Q8WXS4 2 119429901-119438504 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 97.4;liver: 97.6;parathyroid gland: 120.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.4;Hepatocytes: 176.6;Muller glia cells: 131.8;Proximal enterocytes: 530.6;Proximal tubular cells: 173.8;Syncytiotrophoblasts: 130.7" "Cancer enhanced" "Detected in all" "renal cancer: 57.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 32.2" "Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA053794 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA053794: AB_2682265" "unprognostic (2.54e-2)" "unprognostic (3.10e-2)" "unprognostic (1.01e-1)" "unprognostic (4.59e-3)" "unprognostic (2.56e-1)" "unprognostic (9.60e-2)" "unprognostic (5.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.36e-1)" "unprognostic (2.83e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-2)" "unprognostic (2.99e-1)" "unprognostic (2.61e-2)" TMEM41A MGC15397 ENSG00000163900 "Transmembrane protein 41A" Q96HV5 3 185476496-185499057 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 189.6;Squamous epithelial cells: 121.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "HPA059101, HPA059790" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Proximal enterocytes - Digestion" 7 Nucleoplasm "Golgi apparatus, Cytosol" "HPA059101: AB_2683905, HPA059790: AB_2684125" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (6.70e-6)" "unprognostic (2.67e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.84e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.63e-2)" "unprognostic (2.56e-2)" "unprognostic (3.73e-1)" "unprognostic (3.68e-1)" "unprognostic (1.46e-2)" "unprognostic (1.02e-2)" TMEM45B "BC016153, FLJ40787" ENSG00000151715 "Transmembrane protein 45B" Q96B21 11 129815848-129860003 "Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 64.6;intestine: 132.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 79.7;Club cells: 79.2;Distal enterocytes: 262.3;Enteroendocrine cells: 79.6;Ionocytes: 92.4;Paneth cells: 125.7;Proximal enterocytes: 291.2;Undifferentiated cells: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 3.6;neutrophil: 11.8" "Group enriched" "Detected in many" 14 "granulocytes: 11.8;T-cells: 3.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 56.4;prostate cancer: 85.3" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA015474, HPA015878" Approved Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 31 Nucleoplasm "HPA015474: , HPA015878: AB_2205046" "unprognostic (4.92e-3)" "unprognostic (7.94e-2)" "unprognostic (5.98e-2)" "unprognostic (1.81e-1)" "unprognostic (5.44e-3)" "unprognostic (7.11e-2)" "unprognostic (1.17e-1)" "unprognostic (6.53e-2)" "unprognostic (1.76e-1)" "unprognostic (1.02e-3)" "unprognostic (1.33e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (1.42e-2)" "unprognostic (2.24e-1)" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" TMEM54 "BCLP, CAC-1" ENSG00000121900 "Transmembrane protein 54" Q969K7 1 32894594-32901438 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 260.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1854.5;Paneth cells: 671.1;Proximal enterocytes: 472.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060864, HPA061992" Approved Approved Vesicles NA NA "Cluster 45: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 19 Vesicles "HPA060864: , HPA061992: AB_2684652" "unprognostic (2.67e-1)" "unprognostic (2.57e-2)" "unprognostic (2.55e-1)" "unprognostic (4.98e-2)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.42e-2)" "unprognostic (3.48e-2)" "unprognostic (9.43e-2)" "unprognostic (6.82e-3)" "unprognostic (2.13e-2)" "unprognostic (9.06e-2)" "unprognostic (3.12e-2)" "unprognostic (3.40e-2)" TMEM74B "C20orf46, FLJ11190" ENSG00000125895 "Transmembrane protein 74B" Q9NUR3 20 1180561-1185415 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;lung: 26.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 20.6;Enteroendocrine cells: 15.0;Horizontal cells: 23.9;Inhibitory neurons: 15.6;Intestinal goblet cells: 20.5;Paneth cells: 16.5;Proximal enterocytes: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045213 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 24: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 65: Neurons - Synaptic function" "Nucleoplasm, Golgi apparatus" "HPA045213: AB_10961999" "unprognostic (1.51e-1)" "unprognostic (4.38e-2)" "unprognostic (2.37e-1)" "unprognostic (2.05e-3)" "unprognostic (5.73e-2)" "unprognostic (1.03e-2)" "unprognostic (6.91e-3)" "unprognostic (1.97e-1)" "unprognostic (1.77e-4)" "unprognostic (9.58e-2)" "prognostic favorable (3.07e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.55e-7)" "unprognostic (1.20e-1)" "unprognostic (9.77e-2)" "unprognostic (8.37e-2)" "unprognostic (5.07e-3)" TMEM82 ENSG00000162460 "Transmembrane protein 82" A0PJX8 1 15742499-15747982 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 23.7;kidney: 11.2;liver: 51.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 68.8;Hepatocytes: 44.8;Paneth cells: 49.0;Proximal enterocytes: 183.5;Proximal tubular cells: 42.9" "Cancer enhanced" "Detected in some" "liver cancer: 10.2;renal cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA060282 Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 5: Enterocytes - Absorption" Nucleoplasm Cytosol "HPA060282: AB_2684241" "unprognostic (2.46e-2)" "unprognostic (7.96e-2)" "unprognostic (4.88e-2)" "unprognostic (1.40e-2)" "unprognostic (6.45e-2)" "unprognostic (6.90e-2)" "unprognostic (4.80e-2)" "prognostic favorable (3.80e-7)" "unprognostic (1.41e-1)" "unprognostic (5.80e-2)" "unprognostic (4.75e-2)" "unprognostic (1.09e-1)" TMEM98 DKFZP564K1964 ENSG00000006042 "Transmembrane protein 98" Q9Y2Y6 17 32927910-32945106 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 404.0" "Cell type enhanced" "Detected in many" "Mesothelial cells: 197.7;Ovarian stromal cells: 241.9;Proximal enterocytes: 249.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 4.0" "Lineage enriched" "Detected in single" 12 "dendritic cells: 4.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040473, HPA053385" Uncertain Supported Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" 6 Nucleoplasm "HPA040473: AB_10794876, HPA053385: AB_2682134" "unprognostic (1.55e-2)" "unprognostic (5.15e-2)" "unprognostic (4.36e-3)" "unprognostic (7.20e-2)" "unprognostic (1.19e-1)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.14e-4)" "prognostic favorable (7.10e-4)" "unprognostic (6.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.41e-1)" "unprognostic (9.18e-3)" "prognostic favorable (3.85e-4)" "unprognostic (5.16e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (2.58e-1)" TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 271.1;stomach 1: 142.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 264.9;Gastric mucus-secreting cells: 171.0;Paneth cells: 147.3;Prostatic glandular cells: 371.1;Proximal enterocytes: 168.4" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 267.6" "Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 5: Enterocytes - Absorption" 2 "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" TMPRSS7 ENSG00000176040 "Transmembrane serine protease 7" Q7RTY8 3 112034736-112081269 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.3" "Cell type enhanced" "Detected in some" "Ciliated cells: 4.6;Early spermatids: 8.3;Excitatory neurons: 3.9;Intestinal goblet cells: 2.1;Proximal enterocytes: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 1.4" HPA040630 Uncertain NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 42: Ciliated cells - Cilium assembly" "HPA040630: AB_10796124" "unprognostic (4.02e-2)" "unprognostic (9.87e-2)" "unprognostic (9.05e-2)" "unprognostic (2.16e-2)" "unprognostic (2.24e-1)" "unprognostic (4.64e-3)" "unprognostic (6.63e-2)" "unprognostic (2.16e-1)" "unprognostic (2.29e-2)" "unprognostic (4.64e-1)" "unprognostic (1.68e-1)" "unprognostic (1.94e-1)" "unprognostic (7.23e-2)" "unprognostic (2.96e-1)" "unprognostic (2.06e-2)" TMUB1 "C7orf21, HOPS, SB144" ENSG00000164897 "Transmembrane and ubiquitin like domain containing 1" Q9BVT8 7 151081085-151083493 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 188.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029429 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" 7 Nucleoplasm Cytosol "HPA029429: AB_10601825" "unprognostic (8.14e-2)" "unprognostic (2.19e-2)" "unprognostic (2.76e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-3)" "unprognostic (7.04e-2)" "unprognostic (2.12e-3)" "unprognostic (7.73e-2)" "unprognostic (1.25e-1)" "unprognostic (2.93e-2)" "unprognostic (1.74e-2)" "unprognostic (2.24e-1)" "unprognostic (1.97e-2)" "unprognostic (2.49e-3)" "unprognostic (2.74e-1)" "unprognostic (1.03e-1)" "unprognostic (3.31e-2)" TNFRSF10C "CD263, DcR1, LIT, TRAILR3, TRID" ENSG00000173535 "TNF receptor superfamily member 10c" O14798 8 23102921-23117445 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.8;lymphoid tissue: 23.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 2.8;Ionocytes: 3.7;Proximal enterocytes: 4.6;Secretory cells: 3.6;Serous glandular cells: 2.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 3204.8" "Lineage enriched" "Detected in many" 120 "granulocytes: 3204.8" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Testis - Sertoli cells" CAB025635 Enhanced NA NA 14600000 "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 34: Testis cancer - Unknown function" "Cluster 74: Neutrophils - Degranulation" 23 "CAB025635: " "unprognostic (2.63e-1)" "unprognostic (4.49e-3)" "unprognostic (7.21e-3)" "unprognostic (2.07e-2)" "unprognostic (3.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.81e-2)" "unprognostic (2.11e-3)" "unprognostic (5.56e-2)" "unprognostic (4.37e-2)" "unprognostic (8.98e-2)" "unprognostic (1.94e-3)" "unprognostic (2.74e-3)" "unprognostic (4.83e-1)" "unprognostic (1.84e-1)" "unprognostic (1.34e-3)" "unprognostic (6.54e-2)" TNFRSF11A "CD265, FEO, LOH18CR1, ODFR, PDB2, RANK, TRANCE-R" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.4;salivary gland: 24.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 32.3;Enteroendocrine cells: 21.9;Lymphatic endothelial cells: 27.9;Paneth cells: 39.1;Proximal enterocytes: 23.4;Serous glandular cells: 36.3;Undifferentiated cells: 33.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 2.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 2.3" "Cancer enhanced" "Detected in many" "Gastric cancer: 9.7" "Adipose subcutaneous - Macrophages, Kidney - Macrophages, Skeletal muscle - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia, Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Receptor NA NA 110000 "Cluster 15: NK-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 50: Lymphoma - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" TNFRSF14 "ATAR, CD270, HVEA, HVEM, LIGHTR, TR2" ENSG00000157873 "TNF receptor superfamily member 14" Q92956 1 2555639-2565382 "Cancer-related genes, CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 170.8;Proximal enterocytes: 210.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 17.5" "HPA006404, CAB026150, CAB030007" Approved NA NA 110000 "Cluster 33: Non-specific - ATP binding" "Cluster 47: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 22: Proximal enterocytes - Digestion" 4 "CAB026150: , CAB030007: AB_2303380, HPA006404: AB_1851348" "prognostic favorable (4.39e-5)" "unprognostic (3.48e-2)" "unprognostic (1.53e-2)" "prognostic favorable (8.01e-6)" "unprognostic (1.11e-2)" "unprognostic (6.83e-3)" "unprognostic (9.62e-3)" "unprognostic (2.32e-1)" "unprognostic (3.25e-1)" "unprognostic (1.62e-1)" "unprognostic (2.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-2)" "unprognostic (2.72e-2)" "unprognostic (1.58e-1)" "prognostic favorable (7.79e-6)" TNIP1 "ABIN-1, KIAA0113, NAF1, VAN" ENSG00000145901 "TNFAIP3 interacting protein 1" Q15025 5 151029945-151093577 "Human disease related genes, Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 260.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037893, HPA037894, HPA071950" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 56: Non-specific - Unknown function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 67 Nucleoplasm Cytosol "HPA037893: AB_10672468, HPA037894: AB_2675723, HPA071950: AB_2686476" "prognostic favorable (5.69e-4)" "unprognostic (1.08e-1)" "unprognostic (1.10e-1)" "prognostic favorable (6.86e-5)" "unprognostic (7.45e-3)" "unprognostic (2.94e-1)" "unprognostic (5.35e-3)" "unprognostic (1.45e-2)" "unprognostic (2.82e-1)" "unprognostic (3.42e-1)" "unprognostic (2.25e-2)" "unprognostic (1.96e-1)" "unprognostic (7.68e-3)" "unprognostic (1.47e-1)" "unprognostic (4.69e-2)" "unprognostic (2.29e-1)" "unprognostic (9.84e-2)" TNIP2 "ABIN-2, FLIP1, KLIP, MGC4289" ENSG00000168884 "TNFAIP3 interacting protein 2" Q8NFZ5 4 2741648-2756342 "Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Inflammatory response, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 163.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020818, HPA049886, HPA063197" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 22: Proximal enterocytes - Digestion" 7 Nucleoplasm Cytosol "CAB020818: , HPA049886: AB_2680934, HPA063197: AB_2684960" "unprognostic (1.22e-1)" "unprognostic (2.09e-1)" "unprognostic (2.44e-1)" "prognostic favorable (1.13e-4)" "unprognostic (3.64e-1)" "unprognostic (9.87e-2)" "unprognostic (4.36e-2)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.77e-1)" "unprognostic (2.47e-2)" "unprognostic (8.34e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.94e-5)" "unprognostic (3.00e-1)" "unprognostic (7.23e-2)" "unprognostic (1.97e-3)" "unprognostic (4.02e-3)" TONSL "IKBR, NFKBIL2" ENSG00000160949 "Tonsoku like, DNA repair protein" Q96HA7 8 144428775-144444440 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair" "Chromatin regulator" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.4" "Cell type enhanced" "Detected in many" "Langerhans cells: 17.9;Proximal enterocytes: 71.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024679, HPA046494" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 77: Bone marrow - Cell proliferation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 2 Nucleoplasm "Nuclear bodies" "HPA024679: AB_1854441, HPA046494: AB_2679673" "unprognostic (6.68e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.88e-2)" "unprognostic (7.35e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.04e-3)" "unprognostic (7.81e-2)" "unprognostic (4.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.62e-7)" "unprognostic (3.24e-2)" "unprognostic (1.78e-1)" "unprognostic (9.11e-3)" "unprognostic (7.96e-2)" TP53I3 PIG3 ENSG00000115129 "Tumor protein p53 inducible protein 3" Q53FA7 2 24077433-24085861 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 115.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.7;Distal enterocytes: 184.0;Late spermatids: 218.2;Proximal enterocytes: 197.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "CAB017479, HPA022012, HPA028742" Enhanced Supported Vesicles NA NA 250000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 5: Enterocytes - Absorption" Vesicles "CAB017479: AB_2303667, HPA022012: AB_1858202, HPA028742: AB_10603456" "unprognostic (3.66e-2)" "unprognostic (1.41e-3)" "unprognostic (5.55e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-3)" "unprognostic (4.47e-1)" "unprognostic (1.09e-2)" "unprognostic (1.53e-3)" "unprognostic (1.17e-1)" "unprognostic (2.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.75e-1)" "unprognostic (9.89e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-1)" "unprognostic (3.67e-2)" "unprognostic (8.57e-3)" TPRN "C9orf75, DFNB79, FLJ90254" ENSG00000176058 Taperin Q4KMQ1 9 137191617-137204193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.1;pancreas: 88.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 53.0;Distal enterocytes: 163.1;Proximal enterocytes: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 48.0" "HPA020899, HPA076667" Approved Approved "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 1 "Plasma membrane" "HPA020899: AB_1845835, HPA076667: " "unprognostic (5.41e-2)" "prognostic favorable (2.13e-4)" "unprognostic (2.94e-1)" "unprognostic (9.28e-2)" "unprognostic (1.68e-1)" "unprognostic (2.61e-2)" "unprognostic (3.59e-3)" "unprognostic (8.20e-2)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.89e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.16e-9)" "unprognostic (1.96e-3)" "unprognostic (6.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.44e-2)" TRIM3 "BERP, HAC1, RNF22, RNF97" ENSG00000110171 "Tripartite motif containing 3" O75382 11 6448613-6474459 "Predicted intracellular proteins" "Protein transport, Transport" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043396, HPA048233" Enhanced Approved Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 12 Mitochondria "HPA043396: AB_2678460, HPA048233: AB_2680321" "unprognostic (1.24e-1)" "unprognostic (1.98e-1)" "unprognostic (2.31e-1)" "prognostic favorable (2.20e-4)" "unprognostic (4.01e-2)" "unprognostic (3.88e-2)" "unprognostic (1.61e-3)" "unprognostic (2.84e-1)" "unprognostic (2.24e-1)" "unprognostic (3.91e-1)" "prognostic favorable (5.49e-5)" "unprognostic (2.01e-1)" "prognostic unfavorable (1.07e-5)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.93e-1)" TSPAN8 "CO-029, TM4SF3" ENSG00000127324 "Tetraspanin 8" P19075 12 71125085-71441898 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 919.6;stomach 1: 614.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 3097.9;Ductal cells: 947.7;Enteroendocrine cells: 836.8;Intestinal goblet cells: 813.6;Paneth cells: 1988.4;Proximal enterocytes: 3369.5;Undifferentiated cells: 1654.2" "Group enriched" "Detected in many" 4 "colorectal cancer: 283.9;pancreatic cancer: 156.9;stomach cancer: 194.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 618.1;Gastric cancer: 461.0" "Colon - Colon enterocytes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA022273, CAB026009, HPA044337" Enhanced Approved Vesicles NA NA "Cluster 45: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" 4 Vesicles "CAB026009: , HPA022273: , HPA044337: AB_2678899" "unprognostic (1.64e-1)" "unprognostic (2.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.40e-2)" "unprognostic (6.81e-2)" "unprognostic (7.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.01e-3)" "unprognostic (2.93e-1)" "prognostic unfavorable (9.66e-5)" "unprognostic (1.88e-2)" "unprognostic (1.00e-1)" "unprognostic (2.97e-2)" "prognostic favorable (7.36e-5)" TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 547.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 654.9;Hepatocytes: 425.1;Paneth cells: 290.1;Proximal enterocytes: 290.1" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.9;monocytes: 17.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" TTC22 FLJ20619 ENSG00000006555 "Tetratricopeptide repeat domain 22" Q5TAA0 1 54779712-54801323 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 106.5;vagina: 46.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 44.9;Intestinal goblet cells: 31.0;Paneth cells: 32.4;Proximal enterocytes: 51.0;Squamous epithelial cells: 22.7;Suprabasal keratinocytes: 37.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" HPA035072 Uncertain NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA035072: AB_10602252" "prognostic favorable (2.06e-4)" "unprognostic (8.52e-2)" "unprognostic (4.84e-2)" "unprognostic (4.98e-2)" "unprognostic (1.01e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.02e-1)" "unprognostic (2.60e-1)" "unprognostic (3.07e-2)" "unprognostic (4.57e-2)" "unprognostic (7.27e-2)" "unprognostic (1.51e-3)" "unprognostic (5.08e-3)" "unprognostic (1.00e-1)" "unprognostic (3.16e-2)" "unprognostic (2.21e-1)" TTC38 FLJ20699 ENSG00000075234 "Tetratricopeptide repeat domain 38" Q5R3I4 22 46267961-46294008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 227.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 80.6;Hepatocytes: 121.8;NK-cells: 126.4;Proximal enterocytes: 140.5;Proximal tubular cells: 127.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 90.7" "Group enriched" "Detected in all" 4 "granulocytes: 30.0;NK-cells: 38.1;T-cells: 90.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029302, HPA075893" Approved Approved Cytosol NA NA 170000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 19: NK-cells - Adaptive immune response" Cytosol "HPA029302: AB_10601704, HPA075893: " "unprognostic (7.78e-2)" "unprognostic (5.85e-2)" "unprognostic (4.92e-3)" "prognostic favorable (3.21e-6)" "unprognostic (8.34e-2)" "unprognostic (6.38e-2)" "unprognostic (8.72e-2)" "unprognostic (3.62e-2)" "unprognostic (9.45e-2)" "unprognostic (7.22e-2)" "unprognostic (1.12e-1)" "unprognostic (5.66e-2)" "unprognostic (7.34e-3)" "unprognostic (9.02e-2)" "unprognostic (4.12e-1)" "unprognostic (4.97e-1)" "unprognostic (8.33e-2)" UBA7 "D8, UBA1B, UBE1L, UBE2" ENSG00000182179 "Ubiquitin like modifier activating enzyme 7" P41226 3 49805209-49813953 "Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 50.7;granulocytes: 47.1;Proximal enterocytes: 45.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 30.9" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB015444, HPA058182" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA 370000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 57: Platelets - Hemostasis" 2 "Nucleoplasm, Vesicles" Cytosol "CAB015444: AB_793598, HPA058182: AB_2683631" "prognostic favorable (1.55e-4)" "unprognostic (7.07e-3)" "unprognostic (1.59e-2)" "unprognostic (1.61e-2)" "unprognostic (3.77e-1)" "unprognostic (2.31e-2)" "unprognostic (5.08e-3)" "unprognostic (3.61e-2)" "unprognostic (6.33e-2)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (9.11e-2)" "unprognostic (3.81e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.48e-4)" UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636448-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 21.2;intestine: 76.9;stomach 1: 31.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.8;Distal enterocytes: 1.9;Gastric mucus-secreting cells: 4.7;Intestinal goblet cells: 1.2;Paneth cells: 1.4;Proximal enterocytes: 3.3;Squamous epithelial cells: 4.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 81.8;Gallbladder cancer: 131.7;pancreatic cancer: 71.6" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" UQCC3 "C11orf83, UNQ655" ENSG00000204922 "Ubiquinol-cytochrome c reductase complex assembly factor 3" Q6UW78 11 62670273-62673686 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 205.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046851 Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Cytosol "HPA046851: AB_2679839" "unprognostic (5.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.60e-1)" "unprognostic (3.42e-2)" "unprognostic (3.91e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (2.18e-1)" "unprognostic (1.67e-1)" "unprognostic (8.70e-3)" "unprognostic (7.84e-2)" "unprognostic (8.96e-2)" "unprognostic (7.07e-2)" "unprognostic (7.21e-3)" "unprognostic (1.48e-1)" "unprognostic (3.20e-1)" "unprognostic (1.36e-1)" UQCR11 "QCR10, UQCR" ENSG00000127540 "Ubiquinol-cytochrome c reductase, complex III subunit XI" O14957 19 1597169-1605473 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 288.2;skeletal muscle: 301.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2328.4;Distal tubular cells: 2581.7;Hepatocytes: 2187.2;Proximal enterocytes: 2128.1;Proximal tubular cells: 2064.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 23: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.90e-1)" "unprognostic (6.67e-3)" "unprognostic (1.78e-1)" "prognostic favorable (1.23e-4)" "unprognostic (5.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.06e-1)" "unprognostic (5.42e-3)" "unprognostic (9.10e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.86e-4)" "unprognostic (1.03e-1)" "prognostic favorable (1.65e-4)" "unprognostic (2.40e-1)" "unprognostic (1.43e-1)" "unprognostic (2.22e-2)" "unprognostic (1.06e-2)" UQCRQ "QCR8, QP-C, UQCR7" ENSG00000164405 "Ubiquinol-cytochrome c reductase complex III subunit VII" O14949 5 132866630-132868847 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1260.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 5162.2;Hepatocytes: 5456.0;Proximal enterocytes: 2568.7;Proximal tubular cells: 3674.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046693, HPA053323" Approved Enhanced Mitochondria NA NA 18000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA046693: AB_10968453, HPA053323: AB_2682112" "unprognostic (3.22e-1)" "unprognostic (1.06e-1)" "unprognostic (4.92e-2)" "prognostic favorable (4.23e-4)" "unprognostic (1.09e-1)" "unprognostic (9.03e-2)" "unprognostic (1.02e-1)" "unprognostic (3.45e-2)" "unprognostic (1.37e-1)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (3.49e-1)" "unprognostic (1.81e-3)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (3.37e-2)" USH1C "AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C" ENSG00000006611 "USH1 protein network component harmonin" Q9Y6N9 11 17493895-17544416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Hearing" "Cancer-related genes, Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 95.1;kidney: 52.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 203.0;Enteroendocrine cells: 95.9;Intestinal goblet cells: 93.0;Muller glia cells: 154.1;Paneth cells: 173.3;Proximal enterocytes: 432.4;Proximal tubular cells: 179.4;Undifferentiated cells: 94.6" "Group enriched" "Detected in many" 7 "colorectal cancer: 34.5;pancreatic cancer: 18.8;renal cancer: 29.4;stomach cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 76.6;Gastric cancer: 40.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Cholangiocyte, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB013690, HPA027398, HPA027492, HPA028033" Enhanced Enhanced Cytosol No NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 4 Cytosol "CAB013690: , HPA027398: AB_10601775, HPA027492: AB_10601898, HPA028033: AB_10601782" "unprognostic (3.60e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-1)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.51e-2)" "unprognostic (9.65e-2)" "prognostic favorable (9.41e-4)" "unprognostic (1.29e-2)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (2.61e-1)" VAMP8 "EDB, VAMP-8" ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1201.5;Proximal enterocytes: 1181.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Breast - Breast glandular cells, Heart muscle - Macrophages, Skeletal muscle - Macrophages, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Non-specific - Mixed function" 3 "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" VIPR1 "HVR1, RDC1, VPAC1, VPAC1R" ENSG00000114812 "Vasoactive intestinal peptide receptor 1" P32241 3 42489299-42537573 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 128.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 39.6;Distal enterocytes: 54.6;Intestinal goblet cells: 52.2;Paneth cells: 89.4;Proximal enterocytes: 45.2" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 22 "dendritic cells: 2.1;monocytes: 1.8;T-cells: 2.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.7" "Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Group enriched" "Detected in many" 4 "amygdala: 6.4;basal ganglia: 4.5;cerebral cortex: 9.6;hippocampal formation: 7.7;white matter: 2.5" "Low region specificity" "Detected in all" HPA026777 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA026777: AB_10604003" "unprognostic (9.02e-2)" "unprognostic (9.34e-3)" "unprognostic (3.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.28e-1)" "unprognostic (1.47e-2)" "unprognostic (8.89e-4)" "unprognostic (4.00e-3)" "unprognostic (1.03e-1)" "unprognostic (2.95e-2)" "unprognostic (1.28e-2)" "unprognostic (2.72e-1)" "unprognostic (1.82e-3)" "unprognostic (7.70e-2)" "unprognostic (1.69e-1)" "unprognostic (1.03e-2)" "unprognostic (1.05e-2)" VSIG10 ENSG00000176834 "V-set and immunoglobulin domain containing 10" Q8N0Z9 12 118063593-118136026 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA062022 Enhanced Approved "Centriolar satellite,Cytosol" NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 22: Proximal enterocytes - Digestion" Cytosol "Centriolar satellite" "HPA062022: AB_2732675" "unprognostic (1.32e-1)" "unprognostic (7.76e-2)" "unprognostic (2.05e-1)" "unprognostic (4.62e-3)" "unprognostic (1.09e-1)" "unprognostic (6.42e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.53e-4)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (2.49e-1)" "unprognostic (1.75e-1)" "unprognostic (2.85e-2)" "unprognostic (1.17e-1)" "unprognostic (1.80e-2)" "unprognostic (1.48e-2)" VWA7 "C6orf27, G7c, NG37" ENSG00000204396 "Von Willebrand factor A domain containing 7" Q9Y334 6 31765590-31777328 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 20.7" "Cell type enhanced" "Detected in some" "Ciliated cells: 3.9;Distal enterocytes: 2.2;Gastric mucus-secreting cells: 7.7;Proximal enterocytes: 4.8;Proximal tubular cells: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Group enriched" "Detected in some" 5 "cerebellum: 7.0;pons and medulla: 3.9" "Low region specificity" "Detected in many" "HPA046954, HPA054262" Approved Approved "Plasma membrane,Cytosol" "Secreted - unknown location" "No annotated function" NA NA 9200 "Cluster 66: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA046954: AB_2679875, HPA054262: AB_2682430" "unprognostic (9.13e-2)" "unprognostic (8.60e-4)" "unprognostic (9.99e-2)" "unprognostic (2.43e-1)" "unprognostic (2.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.38e-2)" "unprognostic (4.40e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-2)" "unprognostic (1.65e-2)" "unprognostic (9.25e-2)" "prognostic favorable (4.35e-8)" "unprognostic (3.75e-2)" "unprognostic (2.37e-1)" "unprognostic (9.48e-2)" "unprognostic (7.66e-2)" XK "Kx, NA, NAC, X1k, XKR1" ENSG00000047597 "X-linked Kx blood group antigen, Kell and VPS13A binding protein" P51811 X 37685791-37732130 "Blood group antigen proteins, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Blood group antigen" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.0;intestine: 11.8;stomach 1: 11.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 25.9;Enteroendocrine cells: 13.7;Erythroid cells: 33.8;Gastric mucus-secreting cells: 17.7;Proximal enterocytes: 19.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 6.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "basophil: 10.2;eosinophil: 5.8" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Cancer enhanced" "Detected in many" "Myeloma: 12.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019036 Approved Approved Nucleoplasm,Vesicles,Mitochondria No No "Cluster 22: Eosinophils - Transcription" "Cluster 25: Small intestine - Absorption" "Cluster 1: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 1: Erythroid cells - Oxygen transport" Mitochondria "Nucleoplasm, Vesicles" "HPA019036: AB_1846286" "unprognostic (2.37e-2)" "unprognostic (7.13e-3)" "unprognostic (5.03e-2)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "unprognostic (4.56e-1)" "unprognostic (3.59e-2)" "unprognostic (4.00e-2)" "unprognostic (4.77e-3)" "unprognostic (5.07e-2)" "unprognostic (6.63e-2)" "unprognostic (5.90e-2)" "unprognostic (4.44e-8)" "unprognostic (1.74e-1)" "unprognostic (4.75e-2)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" ZBTB7B "c-Krox, hcKrox, ZBTB15, ZFP67, ZNF857B" ENSG00000160685 "Zinc finger and BTB domain containing 7B" O15156 1 155002630-155018523 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 118.8;Proximal enterocytes: 141.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006811, HPA025820" Enhanced Enhanced Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 13: Skin - Cornification" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 5: Enterocytes - Absorption" 11 Nucleoplasm "HPA006811: AB_1859046, HPA025820: AB_1859045" "unprognostic (5.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.45e-1)" "unprognostic (4.36e-2)" "unprognostic (2.43e-1)" "unprognostic (4.95e-3)" "unprognostic (9.55e-2)" "unprognostic (1.41e-1)" "unprognostic (3.72e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.46e-2)" "unprognostic (5.35e-2)" "unprognostic (1.11e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" "unprognostic (1.53e-2)" ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type palmitoyltransferase 12" Q96GR4 9 128720870-128724127 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 250.0;Proximal enterocytes: 192.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 22: Eosinophils - Transcription" "Cluster 48: Stomach - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 4: Extravillous trophoblasts - Unknown function" Nucleoplasm "Intermediate filaments" "HPA059339: AB_2683985" "unprognostic (2.05e-1)" "unprognostic (5.81e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-3)" "unprognostic (5.34e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-1)" "unprognostic (6.42e-2)" "unprognostic (9.97e-2)" "unprognostic (9.41e-2)" "unprognostic (1.09e-2)" "unprognostic (8.82e-3)" "unprognostic (2.18e-1)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" ZFAND2B AIRAPL ENSG00000158552 "Zinc finger AN1-type containing 2B" Q8WV99 2 219195237-219209651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 127.6;Proximal enterocytes: 153.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035159, HPA035160" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 5: Enterocytes - Absorption" 2 "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA035159: AB_2674499, HPA035160: AB_10670697" "unprognostic (3.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.77e-3)" "unprognostic (2.59e-1)" "unprognostic (2.97e-1)" "unprognostic (6.85e-3)" "unprognostic (1.40e-2)" "unprognostic (2.27e-1)" "unprognostic (7.36e-2)" "unprognostic (1.20e-1)" "prognostic favorable (9.38e-4)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-3)" "unprognostic (1.32e-1)" "unprognostic (6.21e-2)" "unprognostic (7.02e-2)" ZZEF1 "FLJ10821, KIAA0399, ZZZ4" ENSG00000074755 "Zinc finger ZZ-type and EF-hand domain containing 1" O43149 17 4004445-4143030 "Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 95.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031778, HPA031790" Uncertain Approved Nucleoplasm,Mitochondria NA NA 1100000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" Nucleoplasm Mitochondria "HPA031778: AB_10599831, HPA031790: AB_10600999" "unprognostic (4.48e-2)" "unprognostic (7.59e-2)" "unprognostic (6.75e-2)" "unprognostic (2.39e-2)" "unprognostic (1.43e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.80e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (2.21e-2)" "prognostic favorable (6.08e-4)" "unprognostic (1.54e-1)" "unprognostic (1.38e-3)" "unprognostic (6.09e-3)" "unprognostic (1.80e-1)" "unprognostic (9.43e-2)" "unprognostic (6.46e-2)"