[{"Gene":"ABCC1","Gene synonym":["GS-X","MRP","MRP1"],"Ensembl":"ENSG00000103222","Gene description":"ATP binding cassette subfamily C member 1","Uniprot":["P33527"],"Chromosome":"16","Position":"15949138-16143257","Protein class":["Cancer-related genes","Disease related genes","Enzymes","FDA approved drug targets","Human disease related genes","Metabolic proteins","Plasma proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Hydrolase","Translocase"],"Disease involvement":["Cancer-related genes","Deafness","FDA approved drug targets","Non-syndromic deafness"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"187.9","Ductal cells":"106.7","Renal nephron cells":"100.9"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid gland - Thyroid glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Oocytes":"8662686.5"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"kidney":"9108315.3","salivary gland":"7671122.9"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA002380","HPA076011"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - ECM organization","Brain expression cluster":"Cluster 21: Non-specific - Metabolism","Cell line expression cluster":"Cluster 7: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":26,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Cell Junctions"],"Antibody RRID":{"HPA002380":"AB_1844432","HPA076011":null},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.49e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.68e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.30e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.60e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.27e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.13e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.71e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.96e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.04e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.30e-5"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.17e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.47e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.12e-1"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.51e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.13e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.36e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.77e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.25e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.61e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.51e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.99e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.63e-1"},"Cancer 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.06e-1"}},{"Gene":"ADAMTSL2","Gene synonym":["KIAA0605"],"Ensembl":"ENSG00000197859","Gene description":"ADAMTS like 2","Uniprot":["Q86TH1"],"Chromosome":"9","Position":"133532164-133575519","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Disease variant","Dwarfism"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"heart muscle":"71.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Fibro-adipogenic progenitors":"67.8","Hepatic stellate cells":"139.6","Microglia":"97.6"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Fibro-adipogenic progenitors":"67.8","Glial cells":"97.6","Stellate cells":"139.6"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"4","RNA single nuclei brain specific nCPM":{"Microglia":"106.7"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"4.5"},"RNA tissue cell type enrichment":["Adrenal gland - Fibroblasts","Kidney - Fibroblasts","Liver - Hepatic stellate cells","Spleen - Fibroblasts_2"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in many","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in many","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"1616","Protein cell type specific Intensity":{"Pancreatic islets":"161605.6"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"lymphoid tissue":"320904.8"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA045634","HPA053812"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted in other tissues","Secretome function":"No annotated function","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"43000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 70: Non-specific - Protein processing","Brain expression cluster":"Cluster 49: Hindbrain - Mixed function","Cell line expression cluster":"Cluster 70: DU4475 - Unknown function","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":null,"Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA045634":"AB_2679399","HPA053812":"AB_2682271"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.36e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.81e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.96e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic 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- Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.58e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"3.28e-5"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.20e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.70e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"5.93e-5"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.18e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.43e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"9.13e-4"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.64e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.38e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.44e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.28e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.64e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.49e-2"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.67e-2"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.53e-1"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.66e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.58e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.11e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.72e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.63e-1"}},{"Gene":"ADRB3","Gene synonym":[],"Ensembl":"ENSG00000188778","Gene description":"Adrenoceptor beta 3","Uniprot":["P13945"],"Chromosome":"8","Position":"37962990-37966599","Protein class":["FDA approved drug targets","G-protein coupled receptors","Human disease related genes","Predicted membrane proteins"],"Biological process":null,"Molecular function":["G protein-coupled receptor","Receptor","Transducer"],"Disease involvement":["Diabetes mellitus","FDA approved drug targets","Obesity"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"fallopian tube":"5.3","ovary":"12.8","urinary bladder":"5.2"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Not detected","RNA single cell type group distribution":"Not detected","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Not detected","RNA single nuclei brain distribution":"Not detected","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Domain enhanced","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":{"medulla oblongata":"15.1"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"169","RNA cell line specific nTPM":{"Bone cancer":"17.7"},"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)","Prostate - Fibroblasts","Stomach - Fibroblasts"],"RNA macaque brain regional specificity":"Not detected","RNA macaque brain regional distribution":"Not detected","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Region enhanced","RNA rat brain regional distribution":"Detected in single","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":{"white matter":"1.7"},"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region group enriched","Antibody":["HPA065408"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Basal body"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 75: Ovary - Mixed function","Brain expression cluster":"Cluster 20: Macrophages & Microglia - Immune response","Cell line expression cluster":"Cluster 12: Bone cancer - Neuronal signaling","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":2,"Subcellular main location":["Vesicles","Basal body"],"Subcellular additional location":null,"Antibody RRID":{"HPA065408":null},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (validation)":null,"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":null,"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":null,"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":null,"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":null,"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":null,"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":null,"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":null,"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"AGAP4","Gene synonym":["AGAP8","CTGLF1","CTGLF5","Em:AC012044.1","MRIP2"],"Ensembl":"ENSG00000188234","Gene description":"ArfGAP with GTPase domain, ankyrin repeat and PH domain 4","Uniprot":["Q96P64"],"Chromosome":"10","Position":"45825594-45853875","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ductal cells":"44.0","Renal nephron cells":"53.2","Spermatogenic cell types":"54.4"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons 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specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region group enriched","Antibody":["HPA051482"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol","Cytoplasmic bodies"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: Non-specific - Transcription & Translation","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response","Brain expression cluster":"Cluster 11: White matter - Signal transduction","Cell line expression cluster":"Cluster 35: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":2,"Subcellular 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specificity":"Not detected","RNA brain domain distribution":"Not detected","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional 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nCPM":{"Mural cells":"38.6","Smooth muscle cells":"18.8"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in single","RNA single nuclei brain specificity score":"10","RNA single nuclei brain specific nCPM":{"Vascular smooth muscle cells":"9.7"},"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Domain enhanced","RNA brain domain distribution":"Detected in all","RNA 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brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in some","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enhanced","Antibody":["HPA011338","CAB026172"],"Reliability 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pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Minor Salivary Gland - Minor salivary 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nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Lung - Respiratory ciliated cells","Skeletal muscle - Fibroblasts","Testis - Early spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in many","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in many","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":null,"Protein cell type distribution":null,"Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":null,"Protein tissue distribution":null,"Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region group enriched","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Ciliated tissues - Cilium organization","Brain expression cluster":"Cluster 17: Choroid plexus - Cilium","Cell line expression cluster":"Cluster 20: Myeloma - Immune response","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (validation)":null,"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.32e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.89e-3"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.87e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.62e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":null,"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.93e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.99e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.08e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.85e-2"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":null,"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":null,"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":null,"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.96e-4"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.19e-2"}},{"Gene":"CCDC71L","Gene synonym":["C7orf74","FLJ36031"],"Ensembl":"ENSG00000253276","Gene description":"Coiled-coil domain containing 71 like","Uniprot":["Q8N9Z2"],"Chromosome":"7","Position":"106654360-106661158","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Ductal cells":"4.4","Megakaryocytes":"2.3","Renal nephron cells":"8.8"},"RNA single nuclei brain specificity":"Not detected","RNA single nuclei brain distribution":"Not detected","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons 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regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"B-cells":"446839.5","Neutrophils":"388993.5","T-cells":"378804.4"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"192","Protein tissue specific Intensity":{"lymphoid tissue":"19176.8"},"Spatial region specificity":"Region group enriched","Antibody":["HPA067925"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Actin filaments","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: Non-specific - DNA binding","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - ECM organization","Brain expression cluster":"Cluster 39: Astrocytes - Mixed function","Cell line expression cluster":"Cluster 64: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":6,"Subcellular main location":["Golgi apparatus","Actin filaments"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA067925":"AB_2685925"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.42e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.72e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.16e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.35e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.31e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.95e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.53e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.98e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.51e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.93e-2"}},{"Gene":"CCN4","Gene synonym":["WISP-1","WISP1","WISP1-OT1","WISP1-UT1"],"Ensembl":"ENSG00000104415","Gene description":"Cellular communication network factor 4","Uniprot":["O95388"],"Chromosome":"8","Position":"133191039-133231690","Protein class":["Cancer-related genes","Predicted secreted proteins"],"Biological process":["Cell adhesion","Wnt signaling pathway"],"Molecular function":null,"Disease involvement":["Cancer-related genes","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Fibroblasts":"37.3","Mural cells":"23.7","Stellate cells":"39.9","Stromal cells":"23.1"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Fibroblasts":"66.0"},"RNA single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in some","RNA single nuclei brain neurons specificity 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blood lineage specific nTPM":null,"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"4","RNA cell line specific nTPM":{"Brain cancer":"22.9","thyroid cancer":"12.5"},"RNA tissue cell type enrichment":["Testis - Peritubular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Region enriched","RNA mouse brain regional distribution":"Detected in some","RNA mouse brain regional specificity score":"5","RNA mouse brain regional specific nTPM":{"olfactory bulb":"7.5"},"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in some","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"6.2"},"RNA rat brain regional specificity":"Region enriched","RNA rat brain regional distribution":"Detected in many","RNA rat brain regional specificity score":"6","RNA rat brain regional specific nTPM":{"spinal cord":"21.8"},"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA007121","CAB012205"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":"Secreted to extracellular matrix","Secretome function":"Cell adhesion","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 75: Ovary - Mixed function","Brain expression cluster":"Cluster 51: Neurons - Mixed function","Cell line expression cluster":"Cluster 72: Neuronal - Signal transduction","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":2,"Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB012205":null,"HPA007121":"AB_1858844"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.45e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.91e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic 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Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.15e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.48e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.37e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"5.32e-5"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.05e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.19e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic 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Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.19e-2"}},{"Gene":"CDC42EP5","Gene synonym":["Borg3","CEP5"],"Ensembl":"ENSG00000167617","Gene description":"CDC42 effector protein 5","Uniprot":["Q6NZY7"],"Chromosome":"19","Position":"54465026-54473296","Protein class":["Predicted intracellular proteins"],"Biological process":["Cell shape"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Papillary tip epithelial cells":"35.3"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Renal nephron cells":"35.3"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in many","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Minor Salivary Gland - Minor salivary glandular cells","Pituitary gland - Fibroblasts","Prostate - Prostate glandular 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type specific Intensity":null,"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"ovary":"3279815.6"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA043449"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Primary cilium","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 12: Smooth muscle tissue - ECM organization","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line expression cluster":"Cluster 57: Stomach & Colon cancer - Digestion","Single cell expression cluster":"Cluster 29: Non-specific - Mixed 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.69e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.81e-2"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.39e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.42e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.48e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic 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distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"16.9","Ductal cells":"29.8","Glial cells":"13.5","Renal nephron cells":"33.5"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific 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rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Large ducts":"2533333.5"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"38","Protein tissue specific Intensity":{"fallopian tube":"3896.9","ovary":"3636.9"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA048873"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Microtubules","Cytokinetic bridge"],"Secretome location":null,"Secretome function":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: 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specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer 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all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":"5468","Protein cell type specific Intensity":{"Keratinocytes":"830834.5","Large ducts":"594540.2","Macrophages":"215168.2"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA042931"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood 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single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"T-reg":"3.9"},"RNA blood lineage 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nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA058451"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Golgi apparatus","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Brain expression cluster":"Cluster 53: Neurons - Mixed function","Cell line expression cluster":"Cluster 51: Myeloma - Immunoglobulins","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":82,"Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":["Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA058451":"AB_2683722"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.44e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell 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Carcinoma (validation)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":null,"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.41e-1"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":null,"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":null,"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"EIF4E3","Gene synonym":["MGC39820"],"Ensembl":"ENSG00000163412","Gene description":"Eukaryotic translation initiation factor 4E family member 3","Uniprot":["Q8N5X7"],"Chromosome":"3","Position":"71675414-71754773","Protein class":["Predicted intracellular proteins"],"Biological process":["Protein biosynthesis","Translation regulation"],"Molecular function":["Initiation factor","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ductal cells":"29.9","Renal nephron cells":"37.2"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain 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brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA058649","HPA076465"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: Neutrophils - Unknown function","Tissue expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 51: Neurons - Mixed function","Cell line expression cluster":"Cluster 51: Myeloma - Immunoglobulins","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":10,"Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":null,"Antibody 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specific nTPM":null,"Protein cell type specificity":null,"Protein cell type distribution":null,"Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":null,"Protein tissue distribution":null,"Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA051330","HPA051798"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Primary cilium","Basal body","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Monocytes & Neutrophils - Degranulation","Tissue expression cluster":"Cluster 74: Non-specific - Signal transduction","Brain expression cluster":null,"Cell line 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brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in some","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Gastric mucous cells","Testis - Early spermatids"],"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein 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specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"6.6","Ductal cells":"13.3","Glial cells":"7.9","Renal nephron cells":"12.9"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single 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(validation)":null,"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.60e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.42e-2"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.08e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.54e-1"},"Cancer prognostics - Lung Squamous 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specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enhanced","Antibody":["HPA000750"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 4: Adrenal gland - 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.37e-3"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.38e-1"}},{"Gene":"HOXC4","Gene synonym":["HOX3","HOX3E"],"Ensembl":"ENSG00000198353","Gene description":"Homeobox C4","Uniprot":["P09017"],"Chromosome":"12","Position":"54016931-54056030","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Developmental protein","DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Fallopian tube ciliated cells":"124.7"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"124.7"},"RNA single nuclei brain specificity":"Group enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"5","RNA single nuclei brain specific nCPM":{"Excitatory":"28.2","Inhibitory":"8.7"},"RNA single nuclei brain neurons specificity":"Group enriched","RNA single nuclei brain neurons distribution":"Detected in some","RNA single nuclei brain neurons specificity score":"4","RNA single nuclei brain neurons specific nCPM":{"Brainstem VGLUT2+ 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Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 75: Ovary - Mixed function","Brain expression cluster":"Cluster 49: Hindbrain - Mixed function","Cell line expression cluster":"Cluster 24: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":56,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053910":"AB_2682305"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.13e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.68e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic 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Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.47e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.23e-2"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.25e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.89e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.48e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic 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channel subfamily A regulatory beta subunit 1","Uniprot":["Q14722"],"Chromosome":"3","Position":"156037701-156539138","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Ion transport","Potassium transport","Transport"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"blood vessel":"91.5","brain":"61.2"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Early spermatids":"41.5","Gonadotrophs":"48.8","Oligodendrocytes":"26.5","Pericytes":"40.7","Vascular smooth 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specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Macrophages":"248244.2","Microglia and Neuropil":"314118.0","Neurons":"641327.2"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"cerebral cortex":"2926558.0"},"Spatial region specificity":"Region enriched (niche group)","Antibody":["HPA036110","HPA044550"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood 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cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"9","RNA single cell type specific nCPM":{"Distal convoluted tubule cells":"122.8","Loop of Henle epithelial cells":"98.7","Papillary tip epithelial cells":"62.3","Podocytes":"109.1","Proximal tubule cells":"113.7","Renal collecting duct intercalated cells":"109.4","Renal collecting duct principal cells":"84.8","Renal connecting tubule cells":"93.0"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"10","RNA single cell type group specific nCPM":{"Ductal cells":"109.4","Renal nephron cells":"122.8"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain 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specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Spleen - Endothelial cells","Testis - Spermatocytes"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Capillaries":"2647070.8"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"lung":"295652.1"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA049606"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Non-specific - Cell proliferation","Tissue expression cluster":"Cluster 69: Parathyroid gland - Mixed function","Brain expression cluster":"Cluster 55: Non-specific - Transcription","Cell line expression cluster":"Cluster 39: Non-specific - Transcription","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":24,"Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA049606":"AB_2680832"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.64e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.22e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic 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cells":"2.2","Renal collecting duct principal cells":"1.6","Renal connecting tubule cells":"1.0"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"8","RNA single cell type group specific nCPM":{"Ductal cells":"2.2","Renal nephron cells":"1.6","Spermatogenic cell types":"3.6"},"RNA single nuclei brain specificity":"Not detected","RNA single nuclei brain distribution":"Not detected","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in single","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA 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brain regional specificity":"Not detected","RNA macaque brain regional distribution":"Not detected","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Not detected","RNA rat brain regional distribution":"Not detected","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 57: Testis - Spermatogenesis","Brain expression cluster":"Cluster 10: Cerebellum - Nucleic acid binding","Cell line expression cluster":"Cluster 56: Non-specific - Sensory perception","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":2,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (validation)":null,"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":null,"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":null,"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular 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tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in all","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei 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Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - Proteolysis","Tissue expression cluster":"Cluster 38: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 33: Neurons - Mixed function","Cell line expression cluster":"Cluster 17: Neuroblastoma - Neuronal signaling","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":18,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"CAB004999":null,"HPA003256":"AB_1079356"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"6.41e-5"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.60e-2"},"Cancer prognostics - Breast Invasive Carcinoma 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specificity":"Not detected","RNA single cell type group distribution":"Not detected","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Not detected","RNA single nuclei brain distribution":"Not detected","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Not detected","RNA brain domain distribution":"Not detected","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA macaque brain regional specificity":"Not detected","RNA macaque brain regional distribution":"Not detected","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional 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(IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Brain expression cluster":null,"Cell line expression cluster":"Cluster 51: Myeloma - Immunoglobulins","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":76,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA014940":"AB_2669122"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon 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(TCGA)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":null,"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":null,"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":null,"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":null,"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"MLXIP","Gene synonym":["bHLHe36","KIAA0867","MIR","MONDOA"],"Ensembl":"ENSG00000175727","Gene description":"MLX interacting protein","Uniprot":["Q9HAP2"],"Chromosome":"12","Position":"122078756-122147344","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological 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single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Minor Salivary Gland - Minor salivary glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional 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specific nTPM":{"amygdala":"32.4","basal ganglia":"15.4","cerebral cortex":"18.7","hippocampal formation":"16.3","thalamus":"8.1"},"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in many","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"33","RNA blood cell specific nTPM":{"memory B-cell":"3.1","naive B-cell":"1.7","plasmacytoid DC":"5.1"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"41","RNA blood lineage specific nTPM":{"B-cells":"3.1","dendritic cells":"5.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adrenal gland - Fibroblasts","Colon - Enteric glia cells","Kidney - Fibroblasts","Skeletal muscle - Fibroblasts","Stomach - Fibroblasts","Testis - Early spermatids","Testis - Late spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in many","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in many","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Astrocytes and Neuropil":"2812987.5","Collecting ducts":"2194941.5","Microglia and Neuropil":"3213070.5","Neurons":"1053736.8"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"skin":"8559322.2"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA035740"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Plasmacytoid DCs - Plasma membrane proteins","Tissue expression cluster":"Cluster 75: Ovary - Mixed function","Brain expression cluster":"Cluster 51: Neurons - Mixed function","Cell line expression cluster":"Cluster 64: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":9,"Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035740":"AB_10610141"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.41e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.14e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.39e-1"},"Cancer 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specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enriched (niche group)","Antibody":["HPA043105"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles","Microtubules","Cytokinetic bridge","Primary cilium","Cytosol","Mid piece","Principal piece","End piece"],"Secretome location":null,"Secretome function":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Monocytes 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.06e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.32e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.33e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.18e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.90e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.16e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma 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nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in single","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Not detected","RNA rat brain regional distribution":"Not detected","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Oocytes":"104233295.5"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific 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(IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 22: Epididymis - Mixed function","Brain expression cluster":null,"Cell line expression cluster":"Cluster 51: Myeloma - Immunoglobulins","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":14,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":null,"Cancer prognostics - 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tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in single","RNA single nuclei brain specificity score":"7","RNA single nuclei brain specific nCPM":{"Inhibitory":"4.7"},"RNA single nuclei brain neurons specificity":"Cell type enriched","RNA single nuclei brain neurons distribution":"Detected in single","RNA single nuclei brain neurons specificity score":"20","RNA single 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distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"746","Protein tissue specific Intensity":{"lymphoid tissue":"74609.0"},"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA015022"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: Eosinophils - 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specificity score":null,"RNA tissue specific nTPM":{"placenta":"9.6"},"RNA single cell type specificity":"Not detected","RNA single cell type distribution":"Not detected","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Not detected","RNA single cell type group distribution":"Not detected","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Not detected","RNA single nuclei brain distribution":"Not detected","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Kidney Chromophobe (TCGA)":"4.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in single","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in single","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Rhabdoid":"7.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Prostate - Fibroblasts","Skin - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in many","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in single","RNA rat brain regional specificity score":null,"RNA rat brain regional specific 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Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.26e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.33e-9"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.24e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.46e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":null,"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.76e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma 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cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"4983","Protein tissue specific Intensity":{"cerebral cortex":"498313.3"},"Spatial region specificity":null,"Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 67: Testis - Mixed function","Brain expression cluster":"Cluster 40: Astrocytes - Astrocyte-neuron interactions","Cell line expression cluster":"Cluster 15: Kidney cancer - Membrane components","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":2,"Subcellular main location":null,"Subcellular additional location":null,"Antibody 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nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in many","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Cardiomyocytes":"444000.3"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA047716"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","Secretome function":"No annotated function","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Mitochondrial translation","Tissue expression cluster":"Cluster 76: Non-specific - Metabolism","Brain expression cluster":"Cluster 28: Oligodendrocytes - Mixed function","Cell line expression cluster":"Cluster 62: Non-specific - Plasma proteins","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":6,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA047716":"AB_2680128"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.20e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic 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Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.23e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.65e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.69e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"PLGLB1","Gene synonym":["PLGL","PRP-B"],"Ensembl":"ENSG00000183281","Gene description":"Plasminogen like B1","Uniprot":["Q02325"],"Chromosome":"2","Position":"87002559-87021852","Protein class":["Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human 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lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enhanced","Antibody":["HPA053770"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","Secretome function":"No annotated function","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1500000000","Blood expression cluster":"Cluster 32: Basophils - Transcription","Tissue expression cluster":"Cluster 53: Liver - Plasma proteins","Brain 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- Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.84e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.89e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.31e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":null,"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer 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(TCGA)":null,"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":null,"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"PPIAL4G","Gene synonym":[],"Ensembl":"ENSG00000236334","Gene description":"Peptidylprolyl isomerase A like 4G","Uniprot":["P0DN37"],"Chromosome":"1","Position":"148482548-148483302","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Isomerase","Rotamase"],"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type 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(TCGA)":null,"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"PPP2R3B","Gene synonym":["PPP2R3L","PPP2R3LY","PR48","PR70"],"Ensembl":"ENSG00000167393","Gene description":"Protein phosphatase 2 regulatory subunit B''beta","Uniprot":["Q9Y5P8"],"Chromosome":"X","Position":"333933-386955","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Group enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"heart muscle":"59.2","skeletal muscle":"87.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in 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distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.55e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.36e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.23e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.79e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.75e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic 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specific nCPM":{"Cardiomyocytes":"4.2","Podocytes":"3.1"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Myocytes":"4.2","Renal nephron cells":"3.1"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in single","RNA single nuclei brain specificity score":"7","RNA single nuclei brain specific nCPM":{"Inhibitory":"2.3"},"RNA single nuclei brain neurons specificity":"Cell type enriched","RNA single nuclei brain neurons distribution":"Detected in single","RNA single nuclei brain neurons specificity score":"7","RNA single nuclei brain neurons specific nCPM":{"Cerebellar Purkinje cells":"2.3"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Glioblastoma Multiforme 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single nuclei brain specific nCPM":{"Astrocytes":"455.0","Fibroblasts":"345.2"},"RNA single nuclei brain neurons specificity":"Group enriched","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":"6","RNA single nuclei brain neurons specific nCPM":{"Hypothalamic VGLUT2+ neurons":"29.4","Midbrain derived inhibitory neurons":"84.2"},"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"7","RNA cancer specific pTPM":{"Breast Invasive Carcinoma (TCGA)":"2.9","Glioblastoma Multiforme (TCGA)":"7.1","Kidney Chromophobe (TCGA)":"8.9","Prostate Adenocarcinoma (TCGA)":"9.3"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"prostate cancer":"1.6","Rhabdoid":"1.6"},"RNA tissue cell type enrichment":["Heart muscle - Smooth muscle cells","Liver - Hepatocytes","Stomach - Parietal cells","Testis - Sertoli cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain 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Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.69e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.16e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.75e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.16e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.01e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.28e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.01e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.07e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.02e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.73e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.09e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.67e-3"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.06e-2"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.45e-2"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.91e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.38e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.44e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.58e-2"},"Cancer 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specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nCPM":{"Distal convoluted tubule cells":"2.8","Loop of Henle epithelial cells":"3.9","Papillary tip epithelial cells":"2.6","Podocytes":"2.9","Proximal tubule cells":"3.4","Renal collecting duct intercalated cells":"3.6","Renal collecting duct principal cells":"3.7","Renal connecting tubule cells":"3.2","Thymocytes":"1.1"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"6","RNA single cell type group specific nCPM":{"Ductal cells":"3.7","Renal nephron cells":"3.9","T-cells":"1.1"},"RNA single nuclei brain specificity":"Not detected","RNA single nuclei brain distribution":"Not detected","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific 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specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Neurons":"207009.3"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"4473","Protein tissue specific Intensity":{"lymphoid tissue":"447326.1"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA034817","HPA043037"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":"Intracellular and membrane","Secretome function":"Enzyme","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Mitochondrial translation","Tissue expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 14: Neurons - Synaptic function","Cell line expression cluster":"Cluster 26: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":20,"Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA034817":null,"HPA043037":"AB_2678280"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.89e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.03e-2"},"Cancer 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enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pancreas":"49.6","pituitary gland":"42.4"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ductal cells":"154.3","Renal nephron cells":"92.8"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Pituitary gland - Somatotropes"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in many","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Pancreatic islets":"7108392.7"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA024311"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - DNA binding","Tissue expression cluster":"Cluster 70: Non-specific - Protein processing","Brain expression cluster":"Cluster 49: Hindbrain - Mixed function","Cell line expression cluster":"Cluster 16: Thyroid cancer - Neuronal signaling","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":22,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA024311":"AB_1856429"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.09e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.63e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.52e-3"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic 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Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.22e-4"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.35e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.15e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.04e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.45e-3"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.41e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic 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specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Not detected","RNA single nuclei brain distribution":"Not detected","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - 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Intensity":null,"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"39339.9","lymphoid tissue":"39277.8"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA036194"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: Monocytes & Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 63: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 37: Neurons - Mixed function","Cell line expression cluster":"Cluster 8: Non-specific - Basic cellular processes","Single cell expression 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brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA049022","HPA057259"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear membrane","Nuclear bodies","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 23: B-cells - Immunoglobulins","Tissue expression cluster":"Cluster 12: Smooth muscle tissue - ECM organization","Brain expression cluster":"Cluster 31: Non-specific - Transcription","Cell line expression cluster":"Cluster 51: Myeloma - Immunoglobulins","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":18,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear membrane","Nuclear bodies","Cytosol"],"Antibody 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.92e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.66e-3"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.06e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.35e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.82e-1"}},{"Gene":"SMARCC2","Gene synonym":["BAF170","CRACC2","Rsc8"],"Ensembl":"ENSG00000139613","Gene description":"SWI\/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2","Uniprot":["Q8TAQ2"],"Chromosome":"12","Position":"56162359-56189567","Protein class":["Disease related 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specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in 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regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["CAB004321","HPA021213","HPA061788"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"8900","Blood expression cluster":"Cluster 45: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 64: Non-specific - Transcription","Brain expression cluster":"Cluster 40: Astrocytes - Astrocyte-neuron interactions","Cell line expression cluster":"Cluster 38: Non-specific - Transcription","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":249,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"CAB004321":null,"HPA021213":"AB_1857275","HPA061788":"AB_2684608"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.37e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.14e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.67e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.04e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.58e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic 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macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Neurons":"21901635.8"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"75889777.2"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA046279","HPA049426"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Non-specific - ATP binding","Tissue expression cluster":"Cluster 39: Testis - Nuclear processes","Brain expression cluster":"Cluster 26: Oligodendrocytes - Mixed function","Cell line expression cluster":"Cluster 26: Non-specific - Mitochondria & RNA binding","Single cell expression 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Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.41e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.92e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.69e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.19e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"7.96e-5"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.04e-3"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic 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Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.04e-1"}},{"Gene":"SOCS5","Gene synonym":["CIS6","Cish5","CISH6","KIAA0671","SOCS-5"],"Ensembl":"ENSG00000171150","Gene description":"Suppressor of cytokine signaling 5","Uniprot":["O75159"],"Chromosome":"2","Position":"46698952-46780245","Protein class":["Predicted intracellular proteins"],"Biological process":["Growth regulation","Ubl conjugation pathway"],"Molecular function":["Signal transduction inhibitor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nCPM":{"Distal convoluted tubule cells":"51.5","Loop of Henle epithelial cells":"46.4","Papillary tip epithelial cells":"29.3","Podocytes":"52.5","Proximal tubule cells":"40.4","Renal collecting duct intercalated cells":"41.3","Renal collecting duct principal cells":"32.7","Renal connecting tubule cells":"40.9"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"6","RNA single cell type group specific nCPM":{"Ductal cells":"41.3","Renal nephron cells":"52.5"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in single","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA020884","CAB025510"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Non-specific - Nuclear processes","Tissue expression cluster":"Cluster 61: Non-specific - Transcription","Brain expression cluster":"Cluster 2: Neurons - Nucleosome","Cell line expression cluster":"Cluster 64: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":16,"Subcellular main location":["Cytosol"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"CAB025510":null,"HPA020884":"AB_1857356"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.74e-3"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.85e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.48e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.56e-3"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.04e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.11e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.39e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.23e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.88e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.48e-2"},"Cancer 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Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.06e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.85e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.62e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.13e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.55e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"9.33e-4"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.97e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.39e-1"}},{"Gene":"SPACA5","Gene synonym":["dJ54B20.3","LYC5","LYZL5","PNPK6288","SLLP2","UNQ6288"],"Ensembl":"ENSG00000171489","Gene description":"Sperm acrosome associated 5","Uniprot":["Q96QH8"],"Chromosome":"X","Position":"48004336-48009733","Protein class":["Enzymes","Predicted secreted proteins"],"Biological process":null,"Molecular function":["Glycosidase","Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific 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domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"granulocytes":"1.2"},"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"18.2"},"RNA tissue cell type enrichment":["Breast - Endothelial cells","Pituitary gland - Thyrotropes","Prostate - Fibroblasts","Stomach - Chief cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Astrocytes and Neuropil":"62994.7","Microglia and Neuropil":"153709.7","Neurons":"98376.1","Pancreatic islets":"149158.5"},"Protein tissue specificity":"Tissue enriched","Protein tissue 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distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Uterine Corpus Endometrial 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blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 13: Lung - Secretion","Brain expression cluster":"Cluster 51: Neurons - Mixed function","Cell line expression cluster":"Cluster 27: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":null,"Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA036971":"AB_2675406","HPA036972":"AB_2675407","HPA064559":"AB_2685286"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.64e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon 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nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Large ducts":"6984558.1","Microglia and Neuropil":"3561057.6"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"lymphoid tissue":"1261485.8","skin":"1945822.6"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA038756"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - 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Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.12e-1"}},{"Gene":"TESK2","Gene synonym":[],"Ensembl":"ENSG00000070759","Gene description":"Testis associated actin remodelling kinase 2","Uniprot":["Q96S53"],"Chromosome":"1","Position":"45343883-45491163","Protein class":["Enzymes","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Kinase","Serine\/threonine-protein kinase","Transferase","Tyrosine-protein kinase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in 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enrichment":["Prostate - Prostate glandular cells","Skin - Keratinocyte (other)","Spleen - B-cells (Spleen)","Testis - Early spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Keratinocytes":"472943.6"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"149","Protein tissue specific Intensity":{"cerebral cortex":"10977.1","lymphoid tissue":"18794.3"},"Spatial region specificity":"Region group enriched","Antibody":["HPA027257","HPA063869"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: Non-specific - DNA binding","Tissue expression cluster":"Cluster 68: Non-specific - 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.11e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.56e-1"}},{"Gene":"THOC3","Gene synonym":["MGC5469","TEX1"],"Ensembl":"ENSG00000051596","Gene description":"THO complex subunit 3","Uniprot":["Q96J01"],"Chromosome":"5","Position":"175917873-176034680","Protein class":["Essential proteins","Predicted intracellular proteins"],"Biological process":["mRNA processing","mRNA splicing","mRNA transport","Transport"],"Molecular function":["RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"10","RNA single nuclei brain specific nCPM":{"Excitatory":"160.8"},"RNA single nuclei brain neurons specificity":"Cell type enriched","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":"10","RNA single nuclei brain neurons specific nCPM":{"Dentate gyrus excitatory":"160.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Stomach - Mitotic cells (Stomach)"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA042764","HPA044009","HPA045071"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 43: Non-specific - Transcription & Translation","Tissue expression cluster":"Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation","Brain expression cluster":"Cluster 29: Forebrain - Mixed function","Cell line expression cluster":"Cluster 22: Non-specific - mRNA splicing & Cell cycle","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":74,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA042764":"AB_10965055","HPA044009":"AB_10959603","HPA045071":"AB_10959461"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.51e-4"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.54e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.00e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"3.28e-4"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.24e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.94e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.99e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.23e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.46e-3"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.52e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.27e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.66e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.48e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.64e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.82e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.41e-3"},"Cancer 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.67e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.45e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.16e-1"}},{"Gene":"TIGAR","Gene synonym":["C12orf5"],"Ensembl":"ENSG00000078237","Gene description":"TP53 induced glycolysis regulatory phosphatase","Uniprot":["Q9NQ88"],"Chromosome":"12","Position":"4307763-4360028","Protein class":["Enzymes","Metabolic proteins","Predicted intracellular proteins"],"Biological process":["Apoptosis","Autophagy"],"Molecular function":["Hydrolase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Cardiomyocytes":"5.9","Distal convoluted tubule cells":"13.9","Loop of Henle epithelial cells":"18.1","Papillary tip epithelial cells":"25.6","Podocytes":"14.0","Proximal tubule cells":"16.0","Renal collecting duct intercalated cells":"25.9","Renal collecting duct principal cells":"32.2","Renal connecting tubule cells":"22.8"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Ductal cells":"32.2","Renal nephron cells":"25.6"},"RNA single nuclei brain specificity":"Not detected","RNA single nuclei brain distribution":"Not detected","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"20.2"},"RNA tissue cell type enrichment":["Pituitary gland - Corticotropes","Testis - Spermatocytes"],"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Cardiomyocytes":"7696258.3","Skeletal myofibers":"7286320.2"},"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["CAB034010","HPA040354","HPA044111"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 37: Monocytes & Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 52: Neurons & Synapses - Synaptic function","Cell line expression cluster":"Cluster 34: Testis cancer - Unknown function","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":22,"Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB034010":null,"HPA040354":"AB_2676935","HPA044111":"AB_2678814"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.88e-3"},"Cancer 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Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.38e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.77e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.94e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.34e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.52e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic 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blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"671","Protein cell type specific Intensity":{"Neurons":"67086.8"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Non-specific - Unknown function","Tissue expression cluster":"Cluster 63: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 26: Oligodendrocytes - Mixed function","Cell 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Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.01e-1"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.87e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.60e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.85e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.98e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.99e-1"}},{"Gene":"TLCD2","Gene synonym":[],"Ensembl":"ENSG00000185561","Gene description":"TLC domain containing 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nCPM":{"Ciliated cells":"2.4","Ductal cells":"5.2","Renal nephron cells":"11.2"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"6.0"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain 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macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in single","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"spinal cord":"18.8"},"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in single","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA046063"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: Non-specific - DNA binding","Tissue expression cluster":"Cluster 28: Liver & Adrenal gland - Secretion","Brain expression cluster":"Cluster 6: Non-specific - Immune response","Cell line expression cluster":"Cluster 72: Neuronal - Signal transduction","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":null,"Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.37e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.18e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.81e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.70e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.38e-1"}},{"Gene":"TNXB","Gene synonym":["HXBL","TN-X","TNX","TNXB1","TNXB2","TNXBS","XB","XBS"],"Ensembl":"ENSG00000168477","Gene description":"Tenascin XB","Uniprot":["P22105"],"Chromosome":"6","Position":"32041153-32115334","Protein class":["Disease related genes","Human disease related genes","Plasma 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epithelial cells":"16.9","Endothelial cells":"25.6","Fibro-adipogenic progenitors":"12.7","Fibroblasts":"23.3"},"RNA single nuclei brain specificity":"Group enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"4","RNA single nuclei brain specific nCPM":{"Fibroblasts":"87.5","Vascular endothelial cells":"30.3"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.09e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":null,"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.50e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.08e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.55e-3"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.52e-3"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.08e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.67e-2"}},{"Gene":"UMAD1","Gene synonym":["RPA3-AS1","RPA3OS"],"Ensembl":"ENSG00000219545","Gene description":"UBAP1-MVB12-associated (UMA) domain containing 1","Uniprot":["C9J7I0"],"Chromosome":"7","Position":"7640711-7968020","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA 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group specific nCPM":{"Ductal cells":"381.8","Renal nephron cells":"287.8"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in some","RNA single nuclei brain specificity score":"5","RNA single nuclei brain specific nCPM":{"Schwann cells":"8.8"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in some","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Adrenal cortex cells","Liver - Hepatocytes","Thyroid gland - Thyroid glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Collecting ducts":"126253.8"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"blood vessel":"3648058.0","skin":"2505458.2"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA044806"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: Neutrophils - Unknown function","Tissue expression cluster":"Cluster 38: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 44: Non-specific - Mixed function","Cell line expression cluster":"Cluster 67: Non-specific - Unknown function","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":6,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody 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cells":"8.4"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"15","RNA single cell type group specific nCPM":{"Ductal cells":"10.6","Renal nephron cells":"14.2"},"RNA single nuclei brain specificity":null,"RNA single nuclei brain distribution":null,"RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":null,"RNA single nuclei brain neurons distribution":null,"RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in many","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in some","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"985","Protein cell type specific Intensity":{"Granulosa cells":"98469.0"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":null,"Antibody":["HPA047217","HPA054023"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 68: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 40: Astrocytes - Astrocyte-neuron interactions","Cell line expression cluster":"Cluster 27: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":52,"Subcellular main location":["Nucleoli"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA047217":"AB_2679987","HPA054023":"AB_2682346"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer 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Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.96e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.09e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.31e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.36e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.58e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic 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tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"102","Protein cell type specific Intensity":{"Cardiomyocytes":"10225.2"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA037497","HPA037498"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 75: Ovary - Mixed function","Brain expression cluster":"Cluster 17: Choroid plexus - Cilium","Cell line expression cluster":"Cluster 28: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 29: Non-specific - Mixed 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.90e-3"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.93e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.14e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.75e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"2.10e-4"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.36e-2"},"Cancer prognostics - Kidney Renal Papillary Cell 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.76e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.56e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.91e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.34e-3"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.58e-5"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.27e-2"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic 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16","Uniprot":["Q05516"],"Chromosome":"11","Position":"114059041-114256765","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation","Ubl conjugation pathway"],"Molecular function":["DNA-binding","Repressor"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability","Proto-oncogene"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Prostate Adenocarcinoma (TCGA)":"25.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"gdT-cell":"22.5","MAIT T-cell":"37.5","naive B-cell":"10.8","NK-cell":"10.0"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"B-cells":"10.8","NK-cells":"10.0","T-cells":"37.5"},"RNA cell line specificity":"Group enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Leukemia":"9.3","prostate cancer":"15.7"},"RNA tissue cell type enrichment":["Spleen - Fibroblasts_2","Testis - Endothelial cells","Thyroid gland - Thyroid glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"3646","Protein cell type specific Intensity":{"Neurons":"364554.4"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA001499","CAB004540"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: Non-specific - Transcription","Tissue expression cluster":"Cluster 14: Adipose tissue - Angiogenesis","Brain expression cluster":"Cluster 53: Neurons - Mixed function","Cell line expression 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.93e-3"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.21e-3"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.20e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.48e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"ZC3H11B","Gene synonym":["ZC3HDC11B"],"Ensembl":"ENSG00000215817","Gene description":"Zinc finger CCCH-type containing 11B","Uniprot":["A0A1B0GTU1"],"Chromosome":"1","Position":"219608012-219613105","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease 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distribution":"Detected in some","RNA single cell type group specificity score":"6","RNA single cell type group specific nCPM":{"Ductal cells":"9.5","Renal nephron cells":"14.4","Spermatogenic cell types":"13.5"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in some","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular smooth muscle cells":"1.7"},"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Not detected","RNA cancer distribution":"Not detected","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Not detected","RNA brain domain distribution":"Not detected","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in single","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"skin cancer":"1.4"},"RNA tissue cell type enrichment":["Heart muscle - Cardiomyocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity 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specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"8150","Protein cell type specific Intensity":{"Skeletal myofibers":"814979.2"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 81: Squamous epithelium - Keratinization","Brain expression cluster":"Cluster 18: Non-specific - Mixed function","Cell line expression cluster":"Cluster 23: Non-specific - Transcription","Single cell expression cluster":"Cluster 29: Non-specific - Mixed function","Interactions":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.23e-3"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.64e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.30e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.49e-3"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.20e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.64e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.82e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.86e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.10e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.30e-3"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.61e-2"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.44e-2"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.17e-4"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.31e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.18e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.84e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.72e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.86e-1"}}]