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specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA021408","HPA022869","HPA023714"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear membrane","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 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genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"adrenal gland":"96.1","intestine":"66.6"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Adrenal cortex cells":"766.7","Enterocytes":"646.1","Vascular endothelial cells":"517.1"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Adrenal endocrine cells":"766.7","Endothelial cells":"517.1","Enterocytes":"646.1"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"31","RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"4580.6"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Kidney Renal Papillary Cell Carcinoma (TCGA)":"35.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"27.2","NK-cell":"17.9"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"NK-cells":"17.9","T-cells":"27.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Adrenal cortex cells","Prostate - Endothelial cells","Spleen - NK-cells (Spleen)"],"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"21.7"},"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Proximal tubules":"76568885.3"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"3491920.0"},"Spatial region specificity":"Region enriched (niche group)","Antibody":["CAB001716","HPA002199","HPA074614"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: Non-specific - Transcription","Tissue expression cluster":"Cluster 4: Adrenal gland - Steroid metabolism","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line expression cluster":"Cluster 70: DU4475 - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":20,"Subcellular main location":["Plasma membrane"],"Subcellular additional 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.36e-2"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":null,"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.74e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.12e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.61e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.10e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.54e-1"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.71e-2"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.33e-2"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.21e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.59e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.90e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"ABCG2","Gene synonym":["ABCP","BCRP","CD338","EST157481","MXR"],"Ensembl":"ENSG00000118777","Gene description":"ATP binding cassette subfamily G member 2 (Junior blood group)","Uniprot":["Q9UNQ0"],"Chromosome":"4","Position":"88090150-88231628","Protein class":["Cancer-related genes","CD markers","Enzymes","Human disease related genes","Metabolic proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":["Cancer-related genes"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"intestine":"83.2"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"4","RNA single cell type specific nCPM":{"Breast lactating cells":"325.9","Colonocytes":"107.1","Enterocytes":"273.8","Extravillous trophoblasts":"119.6","Hofbauer cells":"307.0","Vascular endothelial cells":"141.7"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Endothelial cells":"141.7","Enterocytes":"273.8","Mononuclear phagocytes":"307.0","Secretory cells":"325.9","Trophoblast cells":"119.6"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"22","RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"1855.7"},"RNA single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":{"Lower rhombic lip-derived neurons":"10.0","Midbrain\u2013hindbrain inhibitory neurons":"12.8","Monoaminergic":"8.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Glioblastoma Multiforme (TCGA)":"17.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"MAIT T-cell":"2.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes"],"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Astrocytes and Neuropil":"778032.1","Fallopian tube cells":"365190.5","Macrophages":"326234.8","Microglia and Neuropil":"432738.8"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"3450854.1"},"Spatial region specificity":"Region enriched (niche group)","Antibody":["CAB037299","HPA054719"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Unknown function","Tissue expression cluster":"Cluster 77: Intestine - Digestion","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line expression cluster":"Cluster 53: Squamous epithelial cells - Keratinization","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":12,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"CAB037299":null,"HPA054719":null},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.74e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.71e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.98e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"validated prognostic","is_prognostic":true,"p_val":"3.55e-15"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"favorable","prognostic":"validated prognostic","is_prognostic":true,"p_val":"5.94e-5"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.76e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.22e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.56e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.15e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.62e-3"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.20e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.46e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.14e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"710.1"},"RNA single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":{"Dentate gyrus excitatory":"255.8"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Thyroid gland - Thyroid glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"2718","Protein tissue specific Intensity":{"lymphoid tissue":"271814.2"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA007505"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 9: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 75: Ovary - Mixed function","Brain expression cluster":"Cluster 42: Choroid plexus - Mitochondria","Cell line expression cluster":"Cluster 26: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":34,"Subcellular main 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Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.69e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.30e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.03e-3"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.14e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.31e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.39e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic 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Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.28e-3"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.62e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.08e-3"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.35e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.91e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.36e-2"}},{"Gene":"ADCY4","Gene synonym":["AC4"],"Ensembl":"ENSG00000129467","Gene description":"Adenylate cyclase 4","Uniprot":["Q8NFM4"],"Chromosome":"14","Position":"24318349-24335093","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["cAMP biosynthesis"],"Molecular function":["Lyase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"6","RNA single cell type specific nCPM":{"Lymphatic endothelial cells":"33.0","Vascular endothelial cells":"40.4"},"RNA single cell type group specificity":"Cell type enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"7","RNA single cell type group specific nCPM":{"Endothelial cells":"40.4"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"7","RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"106.9"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in some","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in many","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":"9","RNA blood cell specific nTPM":{"basophil":"2.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":"9","RNA blood lineage specific nTPM":{"granulocytes":"2.9"},"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Adrenal gland - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular endothelial cells","Minor Salivary Gland - Endothelial cells","Pancreas - Endothelial cells","Pituitary gland - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Testis - Endothelial cells","Thyroid gland - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in many","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in many","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"496","Protein cell type specific Intensity":{"Neurons":"49554.4"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["CAB005070","HPA048344"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Mitochondria"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 14: Adipose tissue - Angiogenesis","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line expression cluster":"Cluster 64: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":6,"Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoplasm","Plasma membrane"],"Antibody RRID":{"CAB005070":null,"HPA048344":"AB_2680366"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.90e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.31e-3"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.32e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.74e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.37e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.99e-7"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.18e-3"},"Cancer prognostics - Kidney 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synonym":["ACDCR2","PAQR2"],"Ensembl":"ENSG00000006831","Gene description":"Adiponectin receptor 2","Uniprot":["Q86V24"],"Chromosome":"12","Position":"1688574-1788674","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Fatty acid metabolism","Lipid metabolism"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Oligodendrocytes":"466.9","Renal collecting duct intercalated cells":"273.7"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ductal cells":"273.7","Glial cells":"466.9"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"891.1"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected 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cells","Breast - Adipocytes (Breast)","Minor Salivary Gland - Minor salivary gland basal cells","Stomach - Gastric mucous cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA043737"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 45: Eosinophils - Unknown function","Tissue expression cluster":"Cluster 68: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 11: White matter - Signal transduction","Cell line expression cluster":"Cluster 38: Non-specific - Transcription","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":10,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA043737":"AB_10964205"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.71e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.87e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.20e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.32e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic 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Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.34e-1"}},{"Gene":"AFAP1L2","Gene synonym":["Em:AC005383.4","FLJ14564","KIAA1914","XB130"],"Ensembl":"ENSG00000169129","Gene description":"Actin filament associated protein 1 like 2","Uniprot":["Q8N4X5"],"Chromosome":"10","Position":"114294824-114404756","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"60.8","parathyroid gland":"64.6","thyroid gland":"77.0"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ductal cells":"139.0","Glial cells":"218.2","Renal nephron cells":"129.7","Secretory gland support":"271.7"},"RNA single nuclei brain specificity":"Group enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"5","RNA single nuclei brain specific nCPM":{"Oligodendrocyte progenitor cells":"251.5","Pericytes":"120.0","Schwann cells":"203.7","Vascular endothelial cells":"247.4","Vascular smooth muscle cells":"94.5"},"RNA single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":{"Cerebellar granular cells":"36.6","Upper rhombic lip-derived neurons":"29.8"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Thyroid Carcinoma (TCGA)":"82.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"4","RNA blood lineage specific nTPM":{"B-cells":"1.6","T-cells":"1.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Liver - Hepatic stellate cells","Skin - Outer root sheath cells","Spleen - Endothelial cells","Thyroid gland - Thyroid glandular cells"],"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Region enhanced","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":{"cerebellum":"93.0"},"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Collecting ducts":"35812878.6","Glomeruli":"10405873.2"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"lymphoid tissue":"7501440.9"},"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA037843"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: Non-specific - Transcription & Translation","Tissue expression cluster":"Cluster 33: Thyroid gland - Tissue development","Brain expression cluster":"Cluster 15: Non-specific - Transcription","Cell line expression cluster":"Cluster 15: Kidney cancer - Membrane components","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":2,"Subcellular main location":["Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA037843":"AB_10669990"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.63e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.10e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.96e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.77e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.02e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.88e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.18e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.61e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.38e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.30e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.77e-4"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.81e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"3.75e-4"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.28e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.54e-1"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.87e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.04e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.34e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.19e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.70e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.03e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.22e-4"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.38e-2"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.32e-1"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.44e-2"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.60e-2"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.17e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.84e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.82e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.73e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.43e-2"}},{"Gene":"ALG9","Gene synonym":["DIBD1"],"Ensembl":"ENSG00000086848","Gene description":"ALG9 alpha-1,2-mannosyltransferase","Uniprot":["Q9H6U8"],"Chromosome":"11","Position":"111782195-111871581","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Congenital disorder of glycosylation","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Pancreas epithelial cells":"8247145.8","Pancreatic islets":"6851043.0"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"2039590.3","pancreas":"3404970.7","salivary gland":"1694512.3"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA038575"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Endoplasmic reticulum","Primary cilium","Basal body"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Mitochondrial translation","Tissue expression cluster":"Cluster 8: Pancreas - Proteolysis","Brain expression cluster":"Cluster 10: Cerebellum - Nucleic acid binding","Cell line expression cluster":"Cluster 24: Non-specific - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":10,"Subcellular main location":["Endoplasmic reticulum"],"Subcellular additional location":["Primary cilium","Basal body"],"Antibody RRID":{"HPA038575":"AB_10672718"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.30e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.37e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.25e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.05e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"2.86e-5"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.12e-2"},"Cancer prognostics - 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type specific nCPM":{"Astrocytes":"173.8","Bergmann glia":"168.7","Brain excitatory neurons":"130.0","Brain inhibitory neurons":"111.2","Choroid plexus epithelial cells":"205.7","Ependymal cells":"155.3","Microglia":"214.1","Oligodendrocyte progenitor cells":"144.9","Oligodendrocytes":"193.5","Other brain neurons":"92.1"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"6","RNA single cell type group specific nCPM":{"Ciliated cells":"205.7","Glial cells":"214.1","Neuronal cells":"130.0"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons 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cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Smooth muscle cells":"1718034.8"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"bone marrow":"9345948.7"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA008718"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: Eosinophils - 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group specific nCPM":{"Ciliated cells":"141.0","Glial cells":"193.6"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Schwann cells":"425.3"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain 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specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Alveolar cell types":"712166.8","Smooth muscle cells":"905855.8"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity 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Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.83e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.94e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.27e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.10e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.53e-2"}},{"Gene":"ARNT2","Gene synonym":["bHLHe1","KIAA0307"],"Ensembl":"ENSG00000172379","Gene description":"Aryl hydrocarbon receptor nuclear translocator 2","Uniprot":["Q9HBZ2"],"Chromosome":"15","Position":"80404350-80597933","Protein class":["Disease related genes","Human disease related 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brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Glioblastoma Multiforme (TCGA)":"52.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Smooth muscle cells","Adipose visceral - Mesothelial cells","Testis - Sertoli cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Granulosa cells":"6404983.7"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"641","Protein tissue specific Intensity":{"cerebral 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brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Granulosa cells":"263003.7","Neutrophils":"487514.0"},"Protein tissue specificity":"Tissue 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many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"skeletal muscle":"3363428.4"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA059551"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 14: Neurons - Synaptic function","Cell line expression cluster":"Cluster 26: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":98,"Subcellular main location":["Vesicles"],"Subcellular additional 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Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.97e-3"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.53e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.62e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.96e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.72e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.44e-1"}},{"Gene":"ATP10A","Gene synonym":["ATP10C","ATPVA","ATPVC","KIAA0566"],"Ensembl":"ENSG00000206190","Gene description":"ATPase phospholipid transporting 10A (putative)","Uniprot":["O60312"],"Chromosome":"15","Position":"25677273-25865184","Protein class":["Enzymes","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Lipid transport","Transport"],"Molecular function":["Translocase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"blood vessel":"19.1"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nCPM":{"Podocytes":"2496.6"},"RNA single cell type group specificity":"Cell type enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"5","RNA single cell type group specific nCPM":{"Renal nephron cells":"2496.6"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"6","RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"2699.1"},"RNA single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":{"CA4 Excitatory":"57.2","Forebrain Excitatory":"62.9","Thalamic projection neurons":"101.6"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Skin Cutaneous Melanoma (TCGA)":"11.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional 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cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - DNA binding","Tissue expression cluster":"Cluster 14: Adipose tissue - Angiogenesis","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line expression cluster":"Cluster 64: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 85: Non-specific - Mixed 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Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.08e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.30e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.74e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.39e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.10e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.24e-1"},"Cancer prognostics - Liver 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distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Excitatory":"111.6","Vascular endothelial cells":"113.5"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Mesothelial cells","Testis - Late spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Hepatocytes":"384880.7","Large ducts":"187625.7","Pancreas epithelial cells":"181377.3"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"180","Protein tissue specific Intensity":{"liver":"18038.4"},"Spatial region 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.68e-2"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.26e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.33e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.77e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.05e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.20e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic 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glia":"59.5","Brain excitatory neurons":"87.2","Brain inhibitory neurons":"98.0","Choroid plexus epithelial cells":"62.3","Ependymal cells":"33.5","Microglia":"25.4","Oligodendrocyte progenitor cells":"82.5","Oligodendrocytes":"70.9","Other brain neurons":"67.9"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"15","RNA single cell type group specific nCPM":{"Ciliated cells":"62.3","Glial cells":"82.5","Neuronal cells":"98.0"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Spleen - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA050126"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Unknown function","Tissue expression cluster":"Cluster 76: Non-specific - Metabolism","Brain expression cluster":"Cluster 15: Non-specific - 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pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Glomeruli":"330346597.8","Proximal tubules":"492225278.2"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"kidney":"878981665.8"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA040088","HPA040511"],"Reliability (IH)":"Approved","Reliability (Mouse 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single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":{"Dentate gyrus excitatory":"1135.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Thyroid Carcinoma (TCGA)":"4.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Breast - Endothelial cells","Heart muscle - Endothelial cells","Lung - Alveolar cells type 1","Minor Salivary Gland - Endothelial cells","Prostate - Fibroblasts","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Stomach - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Astrocytes and Neuropil":"180051.1","Microglia and Neuropil":"285285.6"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"3487","Protein tissue specific 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Testicular Germ Cell Tumor (TCGA)":null,"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.44e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"CD59","Gene synonym":["16.3A5","EJ16","EJ30","EL32","G344","MIC11","MIN1","MIN2","MIN3","MSK21","p18-20"],"Ensembl":"ENSG00000085063","Gene description":"CD59 molecule (CD59 blood group)","Uniprot":["P13987"],"Chromosome":"11","Position":"33703010-33736479","Protein class":["Cancer-related genes","CD markers","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant","Hereditary hemolytic anemia"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt 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single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Endothelial cells","Minor Salivary Gland - Minor salivary glandular cells"],"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["CAB001448","HPA026494"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":"Intracellular and membrane","Secretome function":"No annotated function","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"33000000","Blood 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Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":null,"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.37e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"CDH23","Gene synonym":["CDHR23","DFNB12","USH1D"],"Ensembl":"ENSG00000107736","Gene description":"Cadherin related 23","Uniprot":["Q9H251"],"Chromosome":"10","Position":"71396920-71815947","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion","Hearing","Sensory transduction","Vision"],"Molecular function":null,"Disease involvement":["Deafness","Disease variant","Non-syndromic deafness","Retinitis pigmentosa","Usher syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.17e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.68e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.75e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.44e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.19e-3"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.65e-2"},"Cancer 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description":"CMT1A duplicated region transcript 4","Uniprot":["Q8N9R6"],"Chromosome":"17","Position":"15436015-15475728","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"pituitary gland":"30.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"20","RNA single cell type specific nCPM":{"Astrocytes":"56.4","Bergmann glia":"45.4","Brain excitatory neurons":"55.4","Brain inhibitory neurons":"62.3","Choroid plexus epithelial cells":"136.1","Early spermatids":"46.1","Ependymal cells":"113.5","Late spermatids":"54.1","Microglia":"51.4","Oligodendrocyte progenitor cells":"76.4","Oligodendrocytes":"62.2","Other brain neurons":"64.0"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"24","RNA single cell type group specific nCPM":{"Ciliated cells":"136.1","Glial cells":"76.4","Neuronal cells":"64.0","Spermatogenic cell types":"54.1"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA 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specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Late spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in many","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in many","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Not detected","RNA rat brain regional distribution":"Not detected","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"392","Protein cell type specific Intensity":{"Oocytes":"39224.3"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA021590"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - Proteolysis","Tissue expression cluster":"Cluster 20: Pituitary gland - Hormone signaling","Brain expression cluster":"Cluster 1: Neurons - Mixed function","Cell line expression cluster":"Cluster 59: Leukemia - T-cell 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Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.65e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.06e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.07e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.04e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.63e-4"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.49e-3"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic 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Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.17e-2"}},{"Gene":"CFH","Gene synonym":["ARMD4","ARMS1","FHL1","HF","HF1","HF2","HUS"],"Ensembl":"ENSG00000000971","Gene description":"Complement factor H","Uniprot":["P08603"],"Chromosome":"1","Position":"196651754-196752476","Protein class":["Cancer-related genes","Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":["Complement alternate pathway","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease involvement":["Age-related macular degeneration","Cancer-related genes","Disease variant","Hemolytic uremic syndrome"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue 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specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"blood vessel":"239181087.9"},"Spatial region specificity":"Region group enriched","Antibody":["CAB016385","CAB016769","HPA038922","HPA049176","HPA053326"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":"Secreted to blood","Secretome function":"Immunity","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":396000000000,"Blood concentration - Conc. blood MS [pg\/L]":"130000000000","Blood expression cluster":"Cluster 1: T-cells - Unknown function","Tissue expression cluster":"Cluster 45: Liver - Metabolism & Coagulation","Brain expression cluster":"Cluster 42: Choroid plexus - Mitochondria","Cell line expression cluster":"Cluster 71: Lymphoma - Inflammatory response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":16,"Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"CAB016385":null,"CAB016769":null,"HPA038922":"AB_2676271","HPA049176":"AB_2680663","HPA053326":"AB_2682113"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.82e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic 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Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.71e-3"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.75e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.36e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.15e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.68e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.99e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic 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Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.50e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.50e-3"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.08e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.29e-2"}},{"Gene":"CHD4","Gene synonym":["Mi-2b","Mi2-BETA"],"Ensembl":"ENSG00000111642","Gene description":"Chromodomain helicase DNA binding protein 4","Uniprot":["Q14839"],"Chromosome":"12","Position":"6570082-6614524","Protein class":["Cancer-related genes","Disease related genes","Enzymes","Essential proteins","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Chromatin regulator","DNA-binding","Hydrolase"],"Disease involvement":["Cancer-related genes","Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Adrenal cortex cells","Testis - Spermatogonia","Thyroid gland - Thyroid glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"lymphoid tissue":"76594226.0"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA012008"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nucleoplasm","Mitotic spindle","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000","Blood expression cluster":"Cluster 30: Non-specific - DNA binding","Tissue expression cluster":"Cluster 80: Thymus - Adaptive immune response","Brain expression cluster":"Cluster 13: Oligodendrocytes - Mixed function","Cell line expression cluster":"Cluster 38: Non-specific - Transcription","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":434,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Mitotic spindle","Cytosol"],"Antibody RRID":{"HPA012008":"AB_1846633"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.29e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.56e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.35e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.08e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.05e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.70e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.57e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.12e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.81e-1"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.64e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.98e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.69e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.85e-1"},"Cancer 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.90e-2"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.44e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.71e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.60e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.39e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.23e-2"}},{"Gene":"CHKB","Gene synonym":["CHETK","CHKL"],"Ensembl":"ENSG00000100288","Gene description":"Choline kinase beta","Uniprot":["Q9Y259"],"Chromosome":"22","Position":"50578959-50601455","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Lipid biosynthesis","Lipid metabolism","Phospholipid biosynthesis","Phospholipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":["Congenital muscular dystrophy","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Ciliated cells":"23.8","Glial cells":"49.3","Neuronal cells":"40.7"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA018797"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Non-specific - Unknown function","Tissue expression cluster":"Cluster 21: Testis - Mixed function","Brain expression cluster":"Cluster 21: Non-specific - Metabolism","Cell line expression cluster":"Cluster 24: Non-specific - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":2,"Subcellular main 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.41e-2"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.27e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.58e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.61e-1"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.72e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.45e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.28e-2"},"Cancer 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neurons":"10.7","Choroid plexus epithelial cells":"5.7","Ependymal cells":"9.9","Microglia":"20.3","Oligodendrocyte progenitor cells":"10.0","Oligodendrocytes":"16.8","Other brain neurons":"11.3"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"7","RNA single cell type group specific nCPM":{"Ciliated cells":"9.9","Glial cells":"20.3","Neuronal cells":"11.7"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA068473"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"360000","Blood expression cluster":"Cluster 42: Non-specific - Vesicular transport","Tissue expression cluster":"Cluster 68: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line expression cluster":"Cluster 30: Non-specific - Gene expression regulation","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":30,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA068473":"AB_2685994"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.19e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.14e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.23e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.18e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.45e-3"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.86e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.99e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.51e-3"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.77e-3"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"7.64e-4"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"3.04e-4"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic 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Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.84e-2"}},{"Gene":"CLEC3B","Gene synonym":["TN","TNA"],"Ensembl":"ENSG00000163815","Gene description":"C-type lectin domain family 3 member B","Uniprot":["P05452"],"Chromosome":"3","Position":"45001548-45036071","Protein class":["Cancer-related genes","Disease related genes","Plasma proteins","Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":["Cancer-related genes","Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"4","RNA single cell type specific nCPM":{"Ependymal cells":"123.9","Fibroblasts":"35.3","Vascular endothelial cells":"47.2"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Ciliated cells":"123.9","Endothelial cells":"47.2","Fibroblasts":"35.3"},"RNA single nuclei brain specificity":"Group enriched","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":"7","RNA single nuclei brain specific nCPM":{"Ependymal cells":"175.0","Vascular endothelial cells":"673.4"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Kidney Chromophobe (TCGA)":"154.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in some","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Sarcoma":"16.1"},"RNA tissue cell type enrichment":["Adrenal gland - Fibroblasts","Colon - Fibroblasts","Liver - Vascular endothelial cells","Minor Salivary Gland - Fibroblasts","Skeletal muscle - Fibroblasts","Skin - Fibroblasts_1","Thyroid gland - Fibroblasts"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Region enriched","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":"25","RNA rat brain regional specific nTPM":{"spinal cord":"138.9"},"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Smooth muscle cells":"57732250.5"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"blood vessel":"110588937.6","skin":"225742455.2"},"Spatial region specificity":"Region group enriched","Antibody":["CAB002582","HPA034794"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","Secretome function":"No annotated function","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":9130000000,"Blood concentration - Conc. blood MS [pg\/L]":"6600000000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 14: Adipose tissue - Angiogenesis","Brain expression cluster":"Cluster 19: Astrocytes - Mixed function","Cell line expression cluster":"Cluster 64: Connective tissue cells - ECM organization","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":2,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"CAB002582":null,"HPA034794":"AB_2674332"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.07e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.68e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.43e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.99e-5"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.93e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.83e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.38e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.30e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic 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Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.46e-3"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.33e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.72e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.00e-2"}},{"Gene":"CLN3","Gene synonym":["BTN1","BTS","JNCL"],"Ensembl":"ENSG00000188603","Gene description":"CLN3 lysosomal\/endosomal transmembrane protein, battenin","Uniprot":["Q13286"],"Chromosome":"16","Position":"28474111-28495575","Protein class":["Disease related genes","Human disease related genes","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":["Disease variant","Neurodegeneration","Neuronal ceroid lipofuscinosis","Retinitis pigmentosa"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Adrenal cortex cells","Breast - Breast glandular cells","Breast - Breast glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Alveolar cell types":"707180.8"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"121","Protein tissue specific Intensity":{"fallopian tube":"10561.3","liver":"11945.3","lung":"13778.2"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA063280"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Non-specific - Unknown function","Tissue expression cluster":"Cluster 60: Stomach - Digestion","Brain expression cluster":"Cluster 20: Macrophages & Microglia - Immune response","Cell line expression cluster":"Cluster 27: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":44,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA063280":"AB_2684975"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.61e-3"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.32e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.62e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.79e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.77e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.60e-1"}},{"Gene":"CMTM1","Gene synonym":["CKLFH","CKLFH1a","CKLFSF1"],"Ensembl":"ENSG00000089505","Gene description":"CKLF like MARVEL transmembrane domain containing 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spermatids":"55.3","Microglia":"30.4","Oligodendrocyte progenitor cells":"17.5","Oligodendrocytes":"11.6","Other brain neurons":"13.9"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Glial cells":"30.4","Neuronal cells":"13.9","Spermatogenic cell types":"80.6"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"4","RNA blood cell specific nTPM":{"basophil":"8.8","eosinophil":"6.2","neutrophil":"7.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"8.8"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids","Testis - Late spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Not detected","RNA rat brain regional distribution":"Not detected","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":null,"Antibody":["HPA013801"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: Neutrophils - Unknown function","Tissue expression cluster":"Cluster 23: Testis - Spermatogenesis","Brain expression cluster":"Cluster 6: Non-specific - Immune response","Cell line expression cluster":"Cluster 68: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA013801":"AB_1846990"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.89e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.97e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.56e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.46e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.80e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.62e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.27e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.98e-5"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.09e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.29e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.50e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.88e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.85e-3"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"5.08e-4"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.54e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.17e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.51e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.28e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.22e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.24e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.21e-3"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.02e-2"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.02e-1"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.79e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.33e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.62e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.33e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.32e-1"}},{"Gene":"CNOT8","Gene synonym":["CAF1","CALIF","hCAF1","POP2"],"Ensembl":"ENSG00000155508","Gene description":"CCR4-NOT transcription complex subunit 8","Uniprot":["Q9UFF9"],"Chromosome":"5","Position":"154857553-154876792","Protein class":["Enzymes","Housekeeping proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["RNA-mediated gene silencing","Transcription","Transcription regulation","Translation regulation"],"Molecular function":["Exonuclease","Hydrolase","Nuclease","Repressor","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in all","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":"4","RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"186.5"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Macrophages":"38681.6","Neurons":"40807.7","T-cells":"118046.6"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"1050","Protein tissue specific Intensity":{"bone marrow":"179220.5","fallopian tube":"88607.5","lymphoid tissue":"47162.0"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA051398"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Vesicular transport","Tissue expression cluster":"Cluster 15: Bone marrow - Innate immune response","Brain expression cluster":"Cluster 8: Immune cells - Immune response","Cell line expression cluster":"Cluster 22: Non-specific - mRNA splicing & Cell cycle","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":82,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051398":"AB_2681468"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.49e-3"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.77e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.63e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.38e-1"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.14e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.49e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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Intensity":{"B-cells":"57279927.5","Macrophages":"163053090.0","Neutrophils":"92782358.9","T-cells":"90621832.2"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"bone marrow":"57835467.0","intestine":"32841358.9","lung":"22649197.1","lymphoid tissue":"76935950.7"},"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"24000","Blood expression cluster":"Cluster 25: Non-specific - Unknown function","Tissue expression cluster":"Cluster 5: Spleen - Immune response","Brain expression cluster":"Cluster 11: White matter - Signal transduction","Cell line expression 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Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.62e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.84e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.66e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.50e-1"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.29e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.16e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic 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distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"263","Protein cell type specific Intensity":{"Granulosa 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Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.03e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.39e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.53e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.46e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.35e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.01e-2"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic 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(IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":null,"Brain expression cluster":null,"Cell line expression cluster":"Cluster 49: HMC-1 - Innate immune response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":["Nucleoplasm","Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA044735":"AB_2679065","HPA044757":"AB_2679075","HPA046872":"AB_2679849","HPA046987":"AB_2679893"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma 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Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"3.08e-4"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.03e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.41e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.47e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.97e-2"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.24e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.51e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.96e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.66e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.40e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.94e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.56e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA014855"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 33: Non-specific - ATP binding","Tissue expression cluster":"Cluster 63: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 21: Non-specific - Metabolism","Cell line expression cluster":"Cluster 38: Non-specific - Transcription","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":38,"Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody RRID":{"HPA014855":"AB_1847567"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.51e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.64e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic 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Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.65e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.23e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.07e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"DEPDC5","Gene synonym":["DEP.5","KIAA0645"],"Ensembl":"ENSG00000100150","Gene description":"DEP domain containing 5, GATOR1 subcomplex subunit","Uniprot":["O75140"],"Chromosome":"22","Position":"31753867-31908033","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["GTPase activation"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nCPM":{"Astrocytes":"34.1","Bergmann glia":"30.8","Brain excitatory neurons":"40.1","Brain inhibitory neurons":"36.6","Choroid plexus epithelial cells":"84.2","Ependymal cells":"30.8","Microglia":"51.6","Oligodendrocyte progenitor cells":"35.0","Oligodendrocytes":"42.6","Other brain neurons":"24.4"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"7","RNA single cell type group specific nCPM":{"Ciliated cells":"84.2","Glial cells":"51.6","Neuronal cells":"40.1"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"34.9"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"34.9"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Spleen - B-cells (Spleen)","Testis - Sertoli cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"3493","Protein tissue specific Intensity":{"cerebral cortex":"182868.0","fallopian tube":"617999.2","lymphoid tissue":"247001.2"},"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: Eosinophils - Transcription","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response","Brain expression cluster":"Cluster 53: Neurons - Mixed function","Cell line expression cluster":"Cluster 66: Non-specific - Mitochondria","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":30,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.17e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.23e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.21e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.08e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.24e-3"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.89e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.67e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.27e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.16e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.63e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"2.22e-5"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.60e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.85e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.51e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.21e-2"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.38e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.33e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.58e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.65e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.90e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.01e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.77e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.96e-3"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.78e-1"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.30e-2"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.84e-2"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.46e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.48e-3"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.48e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.82e-3"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"DGAT1","Gene synonym":["ARGP1","DGAT"],"Ensembl":"ENSG00000185000","Gene description":"Diacylglycerol O-acyltransferase 1","Uniprot":["O75907"],"Chromosome":"8","Position":"144314584-144326910","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted membrane proteins","Transporters"],"Biological process":["Lipid metabolism"],"Molecular function":["Acyltransferase","Transferase"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Adrenal gland - Adrenal cortex cells","Breast - Adipocytes (Breast)","Testis - Early spermatids","Testis - Late spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"2363676.6"},"Spatial region specificity":"Broadly expressed","Antibody":["CAB032853"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli","Nucleoli rim","Endoplasmic reticulum"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Non-specific - Unknown function","Tissue expression cluster":"Cluster 77: Intestine - Digestion","Brain expression cluster":"Cluster 15: Non-specific - Transcription","Cell line expression cluster":"Cluster 40: Non-specific - Unknown function","Single cell expression cluster":"Cluster 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distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain 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specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Hepatocytes":"3133247.6","Pancreas epithelial cells":"1840596.2"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity 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3L","Uniprot":["Q8TDB6"],"Chromosome":"3","Position":"122564338-122575203","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Antiviral defense","DNA damage","DNA repair","Host-virus interaction","Immunity","Innate immunity","Protein transport","Transport","Ubl conjugation pathway"],"Molecular function":["Chromatin regulator","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in some","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Macrophages":"5989100.4"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"bone marrow":"2965910.7","lymphoid tissue":"3290235.8"},"Spatial region specificity":"Region enriched (niche group)","Antibody":["HPA010570"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Neutrophils - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response","Brain expression cluster":"Cluster 43: Hindbrain - Mixed function","Cell line expression cluster":"Cluster 31: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":48,"Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular 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in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Breast - Breast glandular cells","Testis - Spermatocytes"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA041164","HPA043038"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytoplasmic bodies"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"86000","Blood expression cluster":"Cluster 12: Non-specific - Mitochondrial translation","Tissue expression cluster":"Cluster 1: Choroid plexus - Transmembrane transport","Brain expression cluster":"Cluster 34: Non-specific - Mixed function","Cell line expression cluster":"Cluster 68: Non-specific - Cell cycle regulation","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":89,"Subcellular main location":["Cytoplasmic bodies"],"Subcellular additional 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cells":"10.6","Ependymal cells":"13.4","Microglia":"4.9","Oligodendrocyte progenitor cells":"8.7","Oligodendrocytes":"9.7","Other brain neurons":"3.4","Vascular endothelial cells":"3.9"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"9","RNA single cell type group specific nCPM":{"Ciliated cells":"13.4","Endothelial cells":"3.9","Glial cells":"15.3","Neuronal cells":"5.6"},"RNA single nuclei brain specificity":"Group enriched","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":"8","RNA single nuclei brain specific nCPM":{"Schwann cells":"274.6","Vascular endothelial cells":"133.1"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in some","RNA cancer specificity score":"8","RNA cancer specific pTPM":{"Skin Cutaneous Melanoma (TCGA)":"24.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in many","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell 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specificity score":"14","RNA rat brain regional specific nTPM":{"spinal cord":"119.0"},"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"75","Protein tissue specific Intensity":{"intestine":"7469.1"},"Spatial region specificity":"Region enriched (niche group)","Antibody":["HPA061173"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Vesicles"],"Secretome location":"Secreted - unknown location","Secretome function":"No annotated function","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression 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(validation)":null,"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.06e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.37e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.75e-2"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.05e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic 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Adenocarcinoma (validation)":null,"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.41e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":null,"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.79e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"EIF4A1","Gene synonym":["DDX2A","EIF-4A","EIF4A"],"Ensembl":"ENSG00000161960","Gene description":"Eukaryotic translation initiation factor 4A1","Uniprot":["P60842"],"Chromosome":"17","Position":"7572824-7579006","Protein class":["Enzymes","Essential proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Protein biosynthesis"],"Molecular function":["Helicase","Hydrolase","Initiation factor","RNA-binding"],"Disease 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type group specific nCPM":{"Ciliated cells":"37.8","Glial cells":"83.6","Neuronal cells":"55.0"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Adrenal cortex cells","Colon - Neutrophils"],"RNA macaque brain regional specificity":"Not detected","RNA macaque brain regional distribution":"Not detected","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["CAB011689","HPA068286"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6500000","Blood expression cluster":"Cluster 26: Monocytes - Plasma membrane proteins","Tissue expression cluster":"Cluster 44: Bone marrow - Nuclear processes","Brain expression cluster":"Cluster 21: Non-specific - Metabolism","Cell line expression cluster":"Cluster 42: Non-specific - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":264,"Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"CAB011689":null,"HPA068286":"AB_2685968"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.47e-4"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.00e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.82e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.32e-1"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.66e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.92e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.41e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.55e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.96e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.35e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.35e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.01e-1"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.25e-2"},"Cancer prognostics - 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blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat 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Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.66e-1"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.37e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.48e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.83e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.58e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.61e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic 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nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"1392","Protein cell type specific Intensity":{"Neutrophils":"139177.3"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"14713","Protein tissue specific Intensity":{"lymphoid tissue":"1471253.5"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA008867"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 29: Non-specific - Unknown function","Tissue expression cluster":"Cluster 64: Non-specific - Transcription","Brain expression cluster":"Cluster 12: Non-specific - Vasculature","Cell line expression cluster":"Cluster 57: Stomach & Colon cancer - Digestion","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":96,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA008867":"AB_2668161"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.04e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.37e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.34e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic 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Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.32e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.09e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.19e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.29e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.26e-2"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.90e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.39e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.31e-2"}},{"Gene":"FGD6","Gene synonym":["FLJ11183","ZFYVE24"],"Ensembl":"ENSG00000180263","Gene description":"FYVE, RhoGEF and PH domain containing 6","Uniprot":["Q6ZV73"],"Chromosome":"12","Position":"95076749-95217482","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Guanine-nucleotide releasing factor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in all","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Group enriched","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":"4","RNA single nuclei brain specific nCPM":{"Astrocytes":"119.1","Fibroblasts":"439.1","Macrophages & Monocytes":"164.6","Vascular endothelial cells":"335.6"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer 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in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Adrenal cortex cells","Testis - Spermatogonia"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"8076","Protein tissue specific Intensity":{"lung":"807607.2"},"Spatial region specificity":"Region enriched (niche group)","Antibody":["HPA007974"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 38: Monocytes & Neutrophils - Degranulation","Tissue expression cluster":"Cluster 58: Skin - Keratinization","Brain expression cluster":"Cluster 40: Astrocytes - Astrocyte-neuron interactions","Cell line expression cluster":"Cluster 53: Squamous epithelial cells - Keratinization","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":23,"Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA007974":"AB_1848520"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.79e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.99e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.72e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic 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Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.63e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.11e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.40e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.37e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.44e-1"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.92e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic 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specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"65.9"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Group enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"11","RNA single nuclei brain specific nCPM":{"Lymphocytes":"436.6","Macrophages & Monocytes":"821.0","Microglia":"651.7","Vascular endothelial cells":"1386.1"},"RNA single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in some","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":{"Cholinergic":"6.7","Other Neuron":"4.9"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood 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cells":"224.7","Microglia":"239.7","Oligodendrocyte progenitor cells":"174.9","Oligodendrocytes":"484.5","Other brain neurons":"142.7"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"5","RNA single cell type group specific nCPM":{"Ciliated cells":"303.2","Glial cells":"484.5","Neuronal cells":"177.4"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer 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specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Microglia and Neuropil":"657271.2","Neurons":"1001515.0","T-cells":"1436122.9"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"274","Protein tissue specific Intensity":{"cerebral cortex":"52919.9","fallopian tube":"14793.2","lymphoid tissue":"14476.1"},"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA068099","HPA071213"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: Neutrophils - Protein binding","Tissue 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Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.94e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.71e-3"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.10e-1"}},{"Gene":"FPGT","Gene synonym":["GFPP"],"Ensembl":"ENSG00000254685","Gene description":"Fucose-1-phosphate guanylyltransferase","Uniprot":["O14772"],"Chromosome":"1","Position":"74198238-74234086","Protein class":["Enzymes","Metabolic proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Nucleotidyltransferase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Astrocytes":"43.3","Bergmann glia":"70.0","Brain excitatory neurons":"35.6","Brain inhibitory neurons":"29.3","Choroid plexus epithelial cells":"38.2","Ependymal cells":"58.6","Microglia":"49.1","Oligodendrocyte progenitor cells":"50.1","Oligodendrocytes":"65.7","Other brain neurons":"27.7"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"58.6","Glial cells":"70.0","Neuronal cells":"35.6"},"RNA single nuclei brain specificity":"Low cell type 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specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"pancreas":"1909517.4"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA072331"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 10: Non-specific - Membrane trafficking","Tissue expression cluster":"Cluster 61: Non-specific - Transcription","Brain expression cluster":"Cluster 28: Oligodendrocytes - Mixed function","Cell line expression cluster":"Cluster 37: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA072331":null},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.74e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.02e-1"},"Cancer prognostics - Breast 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protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Microglia":"16.8"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"7.7","Glial cells":"16.8","Neuronal cells":"4.1"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA 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specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"8","RNA cell line specific nTPM":{"Leukemia":"27.2"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Macrophages","Skeletal muscle - Macrophages","Stomach - Parietal cells"],"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA051298"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","Secretome function":"Enzyme","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Non-specific - Innate immune response","Tissue expression cluster":"Cluster 1: Choroid plexus - Transmembrane transport","Brain expression cluster":"Cluster 44: Non-specific - Mixed function","Cell line expression cluster":"Cluster 47: Leukemia - Hemostasis","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051298":"AB_2681428"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.57e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.41e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.42e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.28e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.45e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.21e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.82e-3"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.64e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic 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function":["RNA-binding"],"Disease involvement":["Disease variant"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatogonia"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA037392","HPA037393"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear bodies","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000","Blood expression cluster":"Cluster 43: Non-specific - Transcription & Translation","Tissue expression cluster":"Cluster 63: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 55: Non-specific - Transcription","Cell line expression cluster":"Cluster 22: Non-specific - mRNA splicing & Cell cycle","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":130,"Subcellular main location":["Cytosol"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"HPA037392":"AB_2675453","HPA037393":"AB_10672489"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.54e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic 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Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.29e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.41e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.15e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.37e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.53e-1"}},{"Gene":"GIMAP1","Gene synonym":["HIMAP1","IAN2","IMAP1","IMAP38"],"Ensembl":"ENSG00000213203","Gene description":"GTPase, IMAP family member 1","Uniprot":["Q8WWP7"],"Chromosome":"7","Position":"150716606-150724284","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"23.3"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"7","RNA single cell type specific nCPM":{"Microglia":"37.3"},"RNA single cell type group specificity":"Cell type enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"7","RNA single cell type group specific nCPM":{"Glial cells":"37.3"},"RNA single nuclei brain specificity":"Group enriched","RNA single nuclei brain distribution":"Detected in some","RNA single nuclei brain specificity score":"8","RNA single nuclei brain specific nCPM":{"Lymphocytes":"53.0","Macrophages & Monocytes":"22.1","Microglia":"44.1","Vascular endothelial cells":"81.9"},"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in single","RNA cell line specificity score":"17","RNA cell line specific nTPM":{"Leukemia":"3.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Minor Salivary Gland - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Spleen - Macrophages","Testis - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Macrophages":"61677642.3","T-cells":"62482859.0"},"Protein tissue specificity":"Tissue enhanced","Protein tissue 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domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Heart muscle - Macrophages","Testis - Early spermatids","Testis - Late spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"heart muscle":"12313710.8","kidney":"20188577.4"},"Spatial region specificity":"Broadly expressed","Antibody":["CAB017456","HPA048956","HPA054472"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Golgi apparatus"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Non-specific - Cell proliferation","Tissue expression cluster":"Cluster 67: Testis - Mixed function","Brain expression cluster":"Cluster 15: Non-specific - Transcription","Cell line expression cluster":"Cluster 27: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":130,"Subcellular main location":["Nucleoplasm","Golgi apparatus"],"Subcellular additional location":null,"Antibody 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regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"4845613.6","lymphoid tissue":"3018531.4"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA042987"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: Monocytes & Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 15: Bone marrow - Innate immune response","Brain expression cluster":"Cluster 37: Neurons - Mixed function","Cell line expression cluster":"Cluster 55: Lymphoma - Immune response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":5,"Subcellular main 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cells":"90.3","Kupffer cells":"56.7","Late primary spermatocytes":"206.1","Retinal amacrine cells":"63.0","Retinal bipolar cells":"61.6","Retinal horizontal cells":"75.9"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Mononuclear phagocytes":"90.3","Neuronal cells":"75.9","Spermatogenic cell types":"206.1"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"5","RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"576.6"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low 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score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 32: Cerebral cortex - Mixed function","Cell line expression 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.31e-3"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.52e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.40e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.00e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.89e-2"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.66e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.50e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.40e-1"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.57e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.91e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.32e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.71e-2"}},{"Gene":"HEATR5A","Gene synonym":["C14orf125","DKFZP434I1735","p200b"],"Ensembl":"ENSG00000129493","Gene description":"HEAT repeat containing 5A","Uniprot":["Q86XA9"],"Chromosome":"14","Position":"31291788-31420550","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"121.1"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"7","RNA blood lineage specific nTPM":{"granulocytes":"121.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Adrenal cortex cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"1153438.0","lung":"3201945.8","lymphoid tissue":"3613890.3","salivary gland":"1118921.2"},"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Unknown function","Tissue expression cluster":"Cluster 52: Non-specific - Cellular respiration","Brain expression cluster":"Cluster 49: Hindbrain - Mixed function","Cell line expression cluster":"Cluster 30: Non-specific - Gene expression 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- Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.66e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.87e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.04e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.06e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.19e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.14e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic 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brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Fallopian tube cells":"67368.9"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue 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Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.60e-3"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.52e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.95e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.51e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.65e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.07e-1"}},{"Gene":"HILPDA","Gene synonym":["C7orf68","FLJ21076","HIG-2","HIG2"],"Ensembl":"ENSG00000135245","Gene description":"Hypoxia inducible 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single cell type group specific nCPM":{"Adipocytes":"35.1","Glial cells":"30.3"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Astrocytes":"63.0","Vascular endothelial cells":"60.1"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Kidney Renal Clear Cell Carcinoma (TCGA)":"271.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA 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(IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Lipid droplets"],"Secretome location":"Intracellular and membrane","Secretome function":"Other","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: Eosinophils - Transcription","Tissue expression cluster":"Cluster 81: Squamous epithelium - Keratinization","Brain expression cluster":"Cluster 44: Non-specific - Mixed function","Cell line expression cluster":"Cluster 15: Kidney cancer - Membrane components","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":2,"Subcellular main location":["Lipid droplets"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA010515":"AB_1850710"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic 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Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.53e-3"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.54e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.72e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.25e-2"}},{"Gene":"HLA-E","Gene synonym":[],"Ensembl":"ENSG00000204592","Gene description":"Major histocompatibility complex, class I, E","Uniprot":["P13747"],"Chromosome":"6","Position":"30489509-30494194","Protein class":["Plasma proteins","Predicted membrane proteins","Predicted secreted proteins"],"Biological process":["Adaptive immunity","Host-virus interaction","Immunity","Innate immunity"],"Molecular function":null,"Disease 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single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"457.6"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Liver Hepatocellular Carcinoma (TCGA)":"23.7"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain 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specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"166","Protein cell type specific Intensity":{"T-cells":"16569.9"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity 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(validation)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.64e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.17e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.26e-1"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.36e-4"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.09e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic 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distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Astrocytes":"405.6","Bergmann glia":"181.3","Ependymal cells":"358.2","Microglia":"1427.2","Oligodendrocytes":"194.2"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"12","RNA single cell type group specific nCPM":{"Ciliated cells":"358.2","Glial cells":"1427.2"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in many","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"6.9","monocytes":"3.6","T-cells":"3.1"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enriched (niche group)","Antibody":["CAB017451","CAB032815","HPA052504"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Perinuclear theca","Calyx","Flagellar centriole","Annulus"],"Secretome location":"Intracellular and membrane","Secretome function":"Receptor","CCD Protein":"NA","CCD Transcript":"Yes","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"100000000","Blood expression cluster":"Cluster 4: 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distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Cardiomyocytes":"14491.4","Large ducts":"39163.2"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"25366","Protein tissue specific Intensity":{"fallopian tube":"3025456.6","lymphoid tissue":"2047709.2"},"Spatial region specificity":null,"Antibody":["HPA066812","HPA077228"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoli","Mitochondria"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Mitochondrial translation","Tissue expression cluster":"Cluster 30: Skeletal muscle - Striated muscle contraction","Brain expression cluster":"Cluster 31: Non-specific - Transcription","Cell line expression cluster":"Cluster 8: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":["Mitochondria"],"Subcellular additional location":["Nucleoli"],"Antibody RRID":{"HPA066812":"AB_2685727","HPA077228":null},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.88e-1"},"Cancer 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.64e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.03e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.34e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.49e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.60e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.22e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic 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B-cell":"307.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"39","RNA blood lineage specific nTPM":{"B-cells":"320.1","T-cells":"177.5"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Minor Salivary Gland - Endothelial cells","Testis - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low 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nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Fallopian tube cells":"64335.2","Granulosa cells":"117550.8","Macrophages":"187628.3","Pancreas epithelial cells":"121446.2","T-cells":"123648.5"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"lymphoid tissue":"32850.2"},"Spatial region specificity":"Region enriched (niche group)","Antibody":["HPA027148","HPA043858"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome 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function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"salivary gland":"75.8"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Macrophages & Monocytes":"547.9","Vascular endothelial cells":"496.3"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in single","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Colon - Enteric glia cells","Prostate - Fibroblasts","Testis - Peritubular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Region enhanced","RNA rat brain regional distribution":"Detected in single","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":{"spinal cord":"2.9"},"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"74","Protein cell type specific Intensity":{"Macrophages":"7396.3"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region group enriched","Antibody":["HPA053247","HPA060372"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: Monocytes & Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response","Brain expression cluster":"Cluster 43: Hindbrain - Mixed function","Cell line expression cluster":"Cluster 31: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA053247":"AB_2682088","HPA060372":"AB_2684267"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.01e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.55e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.65e-3"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.40e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.35e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"2.65e-8"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic 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specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"108.5"},"RNA tissue cell type enrichment":["Colon - Endothelial cells"],"RNA macaque brain 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Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","Secretome function":"Receptor","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"700000","Blood expression cluster":"Cluster 10: Non-specific - Membrane trafficking","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line expression cluster":"Cluster 51: Myeloma - Immunoglobulins","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":62,"Subcellular main 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Rectum Adenocarcinoma (validation)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"9.75e-4"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.23e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.08e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.02e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.39e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.22e-1"}},{"Gene":"IRF9","Gene synonym":["ISGF3G"],"Ensembl":"ENSG00000213928","Gene description":"Interferon regulatory factor 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cells":"26.8","Microglia":"51.3","Oligodendrocyte progenitor cells":"56.0","Oligodendrocytes":"19.5","Other brain neurons":"17.6"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"26.8","Glial cells":"56.0","Neuronal cells":"17.6","Secretory gland support":"11.8"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Hepatocytes":"9899868.8"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"1845770.8"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA001862"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: Neutrophils - Protein binding","Tissue expression cluster":"Cluster 5: Spleen - Immune response","Brain expression cluster":"Cluster 43: Hindbrain - Mixed 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.13e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.49e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.25e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.50e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.96e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.55e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential 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Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":"1","Protein tissue specific Intensity":{"liver":"9108830.2"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA006312","HPA016995"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Enhanced","Subcellular location":["Nuclear speckles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 41: Basophils - Unknown function","Tissue expression cluster":"Cluster 63: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 15: Non-specific - Transcription","Cell line expression cluster":"Cluster 63: Non-specific - Protein processing","Single cell expression cluster":"Cluster 85: Non-specific - Mixed 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specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Group enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"4","RNA single nuclei brain specific nCPM":{"Fibroblasts":"121.5","Inhibitory":"198.1","Vascular endothelial cells":"424.3"},"RNA single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":{"Medium Spiny Neurons (MSN)":"198.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Kidney cancer":"23.0"},"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Adrenal gland - Fibroblasts","Breast - Endothelial cells","Heart 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brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Granulosa cells":"35071408.4","Oocytes":"28474024.4"},"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA017956"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Cell Junctions"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 14: Adipose tissue - Angiogenesis","Brain expression 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many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Astrocytes":"27.1","Bergmann glia":"27.5","Brain excitatory neurons":"29.1","Brain inhibitory neurons":"32.1","Choroid plexus epithelial cells":"40.0","Ependymal cells":"36.9","Microglia":"31.2","Oligodendrocyte progenitor cells":"29.7","Oligodendrocytes":"35.4","Other brain neurons":"21.4"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Ciliated cells":"40.0","Glial cells":"35.4","Neuronal cells":"32.1","Secretory gland support":"11.8"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Adrenal cortex cells","Thyroid gland - Thyroid glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":"1230","Protein cell type specific Intensity":{"Fallopian tube cells":"70689.2","Granulosa cells":"212581.4","Neurons":"85604.6"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"64444.4"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA007610"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Mitochondrial translation","Tissue expression cluster":"Cluster 77: Intestine - Digestion","Brain expression cluster":"Cluster 31: Non-specific - Transcription","Cell line expression cluster":"Cluster 37: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":68,"Subcellular main location":["Nucleoli fibrillar center"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA007610":"AB_1852006"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.96e-3"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic 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nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood 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specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"cerebral cortex":"88552238.1"},"Spatial region specificity":"Broadly expressed","Antibody":["CAB009798","HPA052450"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol","Acrosome","Equatorial segment"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6900","Blood expression cluster":"Cluster 25: Non-specific - Unknown function","Tissue expression cluster":"Cluster 27: Cerebellum - Synaptic function","Brain expression cluster":"Cluster 24: Neurons - Mixed function","Cell line expression cluster":"Cluster 30: Non-specific - Gene expression regulation","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":73,"Subcellular main location":["Plasma membrane","Acrosome","Equatorial segment"],"Subcellular additional location":["Nucleoplasm","Cytosol"],"Antibody RRID":{"CAB009798":null,"HPA052450":"AB_2681838"},"Cancer prognostics - 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11","Uniprot":["Q86VZ4"],"Chromosome":"6","Position":"149818757-149864359","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"72.9","Ductal cells":"50.7","Glial cells":"27.6","Neuronal cells":"35.9","Renal nephron cells":"86.6","Spermatogenic cell types":"23.0"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Neurons":"798489.9","Pancreas epithelial cells":"739165.2","Pancreatic islets":"1252923.6"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"pancreas":"1762163.0"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA017267","CAB080609"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"740000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 73: Brain - Neuronal signaling","Brain expression cluster":"Cluster 14: Neurons - Synaptic function","Cell line expression cluster":"Cluster 7: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":2,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"CAB080609":null,"HPA017267":null},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.58e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"7.20e-7"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.21e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.37e-3"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.05e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.27e-2"},"Cancer 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Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.42e-1"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.63e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.36e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.27e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.02e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.46e-3"}},{"Gene":"LUC7L2","Gene synonym":["CGI-59","CGI-74","FLJ10657","H_NH0792N18.3","hLuc7B2","LUC7B2"],"Ensembl":"ENSG00000146963","Gene description":"LUC7 like 2, pre-mRNA splicing factor","Uniprot":["Q9Y383"],"Chromosome":"7","Position":"139340359-139423457","Protein class":["Housekeeping proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in all","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"233.2","Glial cells":"321.9","Neuronal cells":"249.0"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"skin":"128494477.1"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA051631"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 3: Non-specific - Nuclear processes","Tissue expression cluster":"Cluster 64: Non-specific - Transcription","Brain expression cluster":"Cluster 4: Non-specific - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 39: Non-specific - Transcription","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":144,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA051631":"AB_2681558"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"5.64e-4"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.47e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.41e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.75e-3"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.36e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.55e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.02e-1"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.78e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.97e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.83e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.58e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.26e-1"}},{"Gene":"LY6G5B","Gene synonym":["C6orf19","G5b"],"Ensembl":"ENSG00000240053","Gene description":"Lymphocyte antigen 6 family member G5B","Uniprot":["Q8NDX9"],"Chromosome":"6","Position":"31669976-31673776","Protein class":["Predicted intracellular proteins","Predicted secreted proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nCPM":{"Astrocytes":"9.0","Bergmann glia":"8.1","Brain excitatory neurons":"6.6","Brain inhibitory neurons":"6.2","Choroid plexus epithelial cells":"10.1","Ependymal cells":"4.3","Microglia":"6.1","Oligodendrocyte progenitor 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specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Not detected","RNA pig brain regional distribution":"Not detected","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Not detected","RNA rat brain regional distribution":"Not detected","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA048307"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","Secretome function":"No annotated function","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Non-specific - Transcription","Brain expression cluster":"Cluster 16: Non-specific - Transcription","Cell line expression cluster":"Cluster 56: Non-specific - Sensory perception","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA048307":"AB_2680348"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.21e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.29e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.41e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.41e-3"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.64e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.94e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.79e-3"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.26e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.51e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.70e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.24e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.08e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.70e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.45e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.99e-3"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"3.36e-4"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.70e-2"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.35e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.01e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.01e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.30e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.91e-3"}},{"Gene":"MANSC1","Gene synonym":["FLJ10298","LOH12CR3"],"Ensembl":"ENSG00000111261","Gene description":"MANSC domain containing 1","Uniprot":["Q9H8J5"],"Chromosome":"12","Position":"12326056-12350242","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"15","RNA blood cell specific nTPM":{"neutrophil":"98.6"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"39","RNA blood lineage specific nTPM":{"granulocytes":"98.6"},"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in many","RNA cell line specificity score":"6","RNA cell line specific nTPM":{"Bile duct cancer":"134.6"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Adipose visceral - Endothelial cells","Adrenal gland - Adrenal cortex cells","Minor Salivary Gland - Minor salivary glandular cells","Pituitary gland - Thyrotropes","Skeletal muscle - Endothelial cells","Spleen - Neutrophils_2"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"salivary gland":"5624174.3"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA007955","HPA007956"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus","Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1600000","Blood expression cluster":"Cluster 4: Neutrophils - Degranulation","Tissue expression cluster":"Cluster 60: Stomach - Digestion","Brain expression cluster":"Cluster 23: Choroid plexus - Mixed function","Cell line expression cluster":"Cluster 57: Stomach & Colon cancer - Digestion","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":12,"Subcellular main location":["Vesicles"],"Subcellular additional location":["Golgi apparatus"],"Antibody RRID":{"HPA007955":"AB_1079306","HPA007956":"AB_1079305"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"3.61e-4"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.28e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.75e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.42e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.81e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.11e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.86e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.05e-3"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.30e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.25e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"2.17e-8"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.27e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.84e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic 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specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Early spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA042603","HPA057952"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 25: Non-specific - Unknown function","Tissue expression cluster":"Cluster 39: 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Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.57e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.26e-2"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.20e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"validated prognostic","is_prognostic":true,"p_val":"1.81e-7"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"unfavorable","prognostic":"validated prognostic","is_prognostic":true,"p_val":"8.13e-5"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.50e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.47e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.48e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.85e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.67e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.61e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.43e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.32e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.93e-3"}},{"Gene":"MSH5","Gene synonym":["G7"],"Ensembl":"ENSG00000204410","Gene description":"MutS homolog 5","Uniprot":["O43196"],"Chromosome":"6","Position":"31739677-31762676","Protein class":["Disease related genes","Human disease related genes","Plasma proteins","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair","Meiosis"],"Molecular function":["DNA-binding"],"Disease involvement":["Disease variant","Premature ovarian failure"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"11.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"28.0","Glial cells":"16.6","Neuronal cells":"6.3"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain 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type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA078319"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli fibrillar center"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 14: Non-specific - Unknown function","Tissue expression cluster":"Cluster 67: Testis - Mixed function","Brain expression cluster":null,"Cell line expression cluster":"Cluster 35: RS4;11 - Unknown 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specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Microglia and Neuropil":"293613.9"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"3761","Protein tissue specific Intensity":{"cerebral cortex":"436357.7","pancreas":"315824.0"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA043678","HPA055314"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 24: Non-specific - Transcription","Brain 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Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.58e-1"}},{"Gene":"NICN1","Gene synonym":["MGC12936"],"Ensembl":"ENSG00000145029","Gene description":"Nicolin 1, tubulin polyglutamylase complex subunit","Uniprot":["Q9BSH3"],"Chromosome":"3","Position":"49422333-49429326","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nCPM":{"Astrocytes":"2.4","Bergmann glia":"3.1","Brain excitatory neurons":"2.8","Brain inhibitory neurons":"2.9","Choroid plexus epithelial cells":"1.8","Ependymal cells":"1.9","Microglia":"2.8","Oligodendrocyte progenitor cells":"2.5","Oligodendrocytes":"1.9","Other brain neurons":"2.3"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"5","RNA single cell type group specific nCPM":{"Ciliated cells":"1.9","Glial cells":"3.1","Neuronal cells":"2.9"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single 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enhanced","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"testis cancer":"20.4"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts","Testis - Early spermatids"],"RNA macaque brain regional specificity":"Not detected","RNA macaque brain regional distribution":"Not detected","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Fallopian tube cells":"291111.7","Microglia and Neuropil":"125731.7"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA058014"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Non-specific - Cell 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specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Collecting ducts":"73660.6","Granulosa cells":"130018.9"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA009150"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Vesicles","Primary cilium","Primary cilium tip","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 7: Non-specific - Innate immune response","Tissue expression cluster":"Cluster 75: Ovary - Mixed function","Brain expression cluster":"Cluster 11: White matter - Signal transduction","Cell line expression cluster":"Cluster 56: Non-specific - Sensory perception","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":13,"Subcellular main location":["Nucleoli","Primary cilium"],"Subcellular additional location":["Nucleoplasm","Vesicles","Primary cilium tip","Cytosol"],"Antibody RRID":{"HPA009150":"AB_1078086"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.29e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.27e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.08e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.08e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.42e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.59e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.06e-1"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.75e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.61e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.89e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.86e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.71e-2"}},{"Gene":"NPIPB3","Gene synonym":["KIAA0220","NPIPL3"],"Ensembl":"ENSG00000169246","Gene description":"Nuclear pore complex interacting 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specific nCPM":{"Ciliated cells":"7.5","Ductal cells":"8.7","Glial cells":"5.3","Neuronal cells":"3.9","Renal nephron cells":"11.8"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"28.8"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain 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specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA053611"],"Reliability (IH)":null,"Reliability (Mouse 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.26e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.06e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.92e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.22e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.24e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.10e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.71e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.11e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.20e-6"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.04e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.90e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.89e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.49e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.23e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.32e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.00e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.28e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.12e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic 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regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA023566"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression 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Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.94e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.33e-2"}},{"Gene":"OAS3","Gene synonym":[],"Ensembl":"ENSG00000111331","Gene description":"2'-5'-oligoadenylate synthetase 3","Uniprot":["Q9Y6K5"],"Chromosome":"12","Position":"112938051-112976460","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Antiviral defense","Immunity","Innate immunity"],"Molecular function":["Nucleotidyltransferase","RNA-binding","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"49.2"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer 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specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"31471240.5","lymphoid tissue":"25987914.3"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA041253","HPA041372"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Plasma membrane","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 37: Monocytes & Neutrophils - Innate immune response","Tissue expression cluster":"Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response","Brain expression cluster":"Cluster 43: Hindbrain - Mixed function","Cell line expression cluster":"Cluster 31: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":21,"Subcellular main location":["Nucleoplasm","Cytosol"],"Subcellular additional location":["Plasma membrane"],"Antibody RRID":{"HPA041253":"AB_10794990","HPA041372":"AB_10795590"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.88e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.29e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.44e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.32e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.54e-2"}},{"Gene":"OR10AC1","Gene synonym":["OR10AC1P"],"Ensembl":"ENSG00000176510","Gene description":"Olfactory receptor family 10 subfamily AC member 1 (gene\/pseudogene)","Uniprot":[],"Chromosome":"7","Position":"143509256-143519469","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":null,"NeXtProt evidence":null,"RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in single","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"lymphoid tissue":"1.7"},"RNA single cell type specificity":"Cell type enriched","RNA single 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Intensity":{"Macrophages":"16291183.8"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"Stomach":"5809434.6"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA066708"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 28: Neutrophils - Unknown function","Tissue expression cluster":"Cluster 66: Lymphoid tissue - Immune response","Brain expression cluster":"Cluster 43: Hindbrain - Mixed function","Cell line expression cluster":"Cluster 31: Non-specific - Antiviral immune response","Single cell expression 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Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.50e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.78e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.32e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.84e-3"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.97e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.02e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic 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specificity score":null,"RNA cell line specific nTPM":{"Neuroblastoma":"10.8"},"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Prostate - Fibroblasts","Spleen - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"282","Protein cell type specific Intensity":{"Microglia and Neuropil":"28174.5"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"9228","Protein tissue specific Intensity":{"cerebral cortex":"922816.2"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA007692"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"31000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 74: Non-specific - Signal 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Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.37e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.33e-2"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.80e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.20e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.27e-2"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.46e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.27e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.00e-2"}},{"Gene":"PCDHGA11","Gene synonym":["PCDH-GAMMA-A11"],"Ensembl":"ENSG00000253873","Gene description":"Protocadherin gamma subfamily A, 11","Uniprot":["Q9Y5H2"],"Chromosome":"5","Position":"141421047-141512975","Protein class":["Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Choroid plexus epithelial cells":"2.4"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Ciliated cells":"2.4","Glial cells":"1.3"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer 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cell type specificity score":"5690","Protein cell type specific Intensity":{"Microglia and Neuropil":"569028.2"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"intestine":"580127.2","skin":"1334881.8"},"Spatial region specificity":"Region group enriched","Antibody":["HPA010580"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane","Cytosol"],"Secretome location":"Intracellular and membrane","Secretome function":"Cell adhesion","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Brain & retina - Neuronal signaling","Brain expression cluster":"Cluster 15: Non-specific - Transcription","Cell line 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.07e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.68e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.74e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.62e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.92e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.61e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic 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specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Spleen - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Fallopian tube cells":"146843.7","Neurons":"122707.8"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA063531"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 64: Non-specific - 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specific nCPM":{"Late spermatids":"45.6","Oligodendrocytes":"38.8"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Glial cells":"38.8","Spermatogenic cell types":"45.6"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Adipocytes (Breast)"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Granulosa cells":"163167.6","Keratinocytes":"278789.9","Large ducts":"320484.8"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"713","Protein tissue specific Intensity":{"heart muscle":"71316.8"},"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA059549"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Endoplasmic reticulum"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Non-specific - Unknown function","Tissue expression cluster":"Cluster 68: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 30: White matter - Myelination","Cell line 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specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region 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protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"16","RNA single cell type specific nCPM":{"Astrocytes":"12.9","Bergmann glia":"11.0","Brain excitatory neurons":"14.0","Brain inhibitory neurons":"14.2","Choroid plexus epithelial cells":"11.6","Ependymal cells":"21.7","Microglia":"9.6","Oligodendrocyte progenitor cells":"18.7","Oligodendrocytes":"11.9","Other brain neurons":"11.9"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"21","RNA single cell type group specific nCPM":{"Ciliated cells":"21.7","Glial cells":"18.7","Neuronal cells":"14.2"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain 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specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"lymphoid tissue":"2277271.6"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA069291"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: Eosinophils - Transcription","Tissue expression cluster":"Cluster 73: Brain - Neuronal signaling","Brain expression cluster":"Cluster 51: Neurons - Mixed function","Cell line expression cluster":"Cluster 23: Non-specific - Transcription","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":142,"Subcellular main 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neurons":"5.3","Choroid plexus epithelial cells":"2.2","Ependymal cells":"3.1","Microglia":"2.1","Oligodendrocyte progenitor cells":"4.7","Oligodendrocytes":"4.1","Other brain neurons":"5.9"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"8","RNA single cell type group specific nCPM":{"Ciliated cells":"3.1","Glial cells":"6.6","Neuronal cells":"5.9"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Adipose visceral - Adipose progenitor cells","Liver - Vascular endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Large ducts":"1228743.4"},"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enhanced","Antibody":["HPA048387","HPA068609"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Mitochondria"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 43: Non-specific - Transcription & Translation","Tissue expression cluster":"Cluster 74: Non-specific - Signal transduction","Brain expression cluster":"Cluster 44: Non-specific - Mixed function","Cell line expression cluster":"Cluster 42: Non-specific - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":56,"Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA048387":"AB_2680381","HPA068609":"AB_2686011"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.93e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.47e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.54e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.09e-3"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.04e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.12e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.02e-3"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.35e-3"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.73e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.06e-2"},"Cancer 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.10e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.43e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.33e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.54e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.83e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.72e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.72e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.23e-2"}},{"Gene":"PMF1","Gene synonym":[],"Ensembl":"ENSG00000160783","Gene description":"Polyamine modulated factor 1","Uniprot":["Q6P1K2"],"Chromosome":"1","Position":"156212993-156240042","Protein class":["Essential proteins","Predicted intracellular proteins"],"Biological process":["Cell cycle","Cell division","Chromosome partition","Mitosis","Transcription","Transcription regulation"],"Molecular function":["Activator"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity 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cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type 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specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA031240","HPA055593"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitotic spindle","Centriolar satellite"],"Secretome location":null,"Secretome function":null,"CCD Protein":"Yes","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 5: Spleen - Immune response","Brain expression cluster":"Cluster 6: Non-specific - Immune response","Cell line expression cluster":"Cluster 57: Stomach & Colon cancer - Digestion","Single cell expression cluster":"Cluster 85: 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.44e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.44e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.47e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.32e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":null,"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.19e-1"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.54e-3"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.04e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.12e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.26e-1"}},{"Gene":"PRORP","Gene synonym":["KIAA0391","MRPP3"],"Ensembl":"ENSG00000100890","Gene description":"Protein only RNase P catalytic subunit","Uniprot":["O15091"],"Chromosome":"14","Position":"35121846-35277622","Protein class":["Disease related 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enrichment":["Adrenal gland - Adrenal cortex cells","Stomach - Mitotic cells (Stomach)","Testis - Spermatocytes"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"pancreas":"1026457.9"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA020459"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Mitochondria"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 39: T-cells - T-cell receptor","Tissue expression cluster":"Cluster 76: Non-specific - Metabolism","Brain expression cluster":"Cluster 50: Non-specific - Nucleic acid 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Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.02e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.60e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.31e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"6.28e-4"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.37e-2"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.12e-1"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic 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synonym":["PRGP1"],"Ensembl":"ENSG00000130962","Gene description":"Proline rich and Gla domain 1","Uniprot":["O14668"],"Chromosome":"X","Position":"37349309-37457292","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"40.4"},"RNA single cell type specificity":"Cell type enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nCPM":{"Oligodendrocytes":"239.5"},"RNA single cell type group specificity":"Cell type enriched","RNA single cell type group 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regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Breast - Endothelial cells","Colon - Endothelial cells","Skin - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Conserved niche marker","Antibody":["HPA078129"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Vesicles","Plasma membrane"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 3: Oligodendrocytes - Myelination","Brain expression cluster":"Cluster 30: White matter - Myelination","Cell line expression cluster":"Cluster 15: Kidney cancer - Membrane components","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":17,"Subcellular main location":["Vesicles","Plasma membrane"],"Subcellular additional location":["Nucleoplasm"],"Antibody 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Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.05e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.89e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.21e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.62e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"9.27e-7"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.29e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic 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cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Bergmann glia":"203.0","Vascular endothelial cells":"278.0"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Testicular Germ Cell Tumor (TCGA)":"4.2"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific 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specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in all","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity 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enrichment":["Prostate - Prostate basal glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Alveolar cell types":"4665700.2"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"fallopian tube":"743646.5"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA020106","HPA047679"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Non-specific - Cell proliferation","Tissue expression cluster":"Cluster 24: Non-specific - Transcription","Brain expression cluster":"Cluster 6: Non-specific - Immune response","Cell line 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.17e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.84e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.62e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.43e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.18e-3"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"2.79e-4"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.34e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.39e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.60e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.03e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.19e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.15e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.68e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.34e-2"}},{"Gene":"PTGR2","Gene synonym":["FLJ39091","ZADH1"],"Ensembl":"ENSG00000140043","Gene description":"Prostaglandin reductase 2","Uniprot":["Q8N8N7"],"Chromosome":"14","Position":"73851831-73885726","Protein class":["Enzymes","Predicted intracellular proteins"],"Biological process":["Lipid metabolism"],"Molecular function":["Oxidoreductase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"37.3","Glial cells":"22.7","Myocytes":"18.6","Neuronal cells":"14.3"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"basophil":"6.2"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Adrenal cortex cells","Heart muscle - Cardiomyocytes","Testis - Spermatocytes","Testis - Spermatogonia","Thyroid gland - Thyroid glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Skeletal myofibers":"20680900.0"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"heart muscle":"69028924.8"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA001125"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"32000","Blood expression cluster":"Cluster 30: Non-specific - DNA binding","Tissue expression cluster":"Cluster 52: Non-specific - Cellular respiration","Brain expression cluster":"Cluster 46: Brainstem - Mixed function","Cell line expression cluster":"Cluster 30: Non-specific - Gene expression regulation","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":6,"Subcellular main location":["Vesicles"],"Subcellular additional location":null,"Antibody RRID":{"HPA001125":"AB_2666207"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.95e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.97e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.05e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.05e-1"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.06e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.28e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.90e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.83e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.33e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic 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mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Granulosa cells":"3752089.3"},"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region 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group distribution":"Detected in some","RNA single cell type group specificity score":"9","RNA single cell type group specific nCPM":{"Ciliated cells":"24.1","Glial cells":"58.8","Neuronal cells":"20.0"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"cerebral cortex":"18941860.0"},"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"1800000","Blood expression cluster":"Cluster 29: Non-specific - Unknown function","Tissue expression cluster":"Cluster 3: Oligodendrocytes - Myelination","Brain expression cluster":"Cluster 27: Non-specific - Mixed function","Cell line expression cluster":"Cluster 35: RS4;11 - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":12,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.52e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.11e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.84e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.31e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.62e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.14e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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1","Uniprot":["Q9UJ41"],"Chromosome":"7","Position":"66682164-66811464","Protein class":["Predicted intracellular proteins","Transporters"],"Biological process":["Endocytosis","Protein transport","Transport","Ubl conjugation pathway"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"bone marrow":"72.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":"5","RNA single cell type specific nCPM":{"Astrocytes":"193.2","Bergmann glia":"182.0","Brain excitatory neurons":"199.9","Brain inhibitory neurons":"213.2","Choroid plexus epithelial cells":"301.0","Ependymal cells":"162.0","Microglia":"149.7","Oligodendrocyte progenitor cells":"174.2","Oligodendrocytes":"335.0","Other brain neurons":"233.3"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"7","RNA single cell type group specific nCPM":{"Ciliated cells":"301.0","Glial cells":"335.0","Neuronal cells":"233.3"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell 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blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"6300","Blood expression cluster":"Cluster 5: Non-specific - Cell proliferation","Tissue expression cluster":"Cluster 74: Non-specific - Signal transduction","Brain expression cluster":"Cluster 9: Non-specific - Receptor signaling","Cell line expression cluster":"Cluster 22: Non-specific - mRNA splicing & Cell cycle","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":139,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies"],"Antibody RRID":{"CAB022103":null,"CAB024979":null,"CAB080379":null,"HPA052291":"AB_2681786"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.57e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.02e-3"},"Cancer prognostics - 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protein","GTPase activation","Guanine-nucleotide releasing factor"],"Disease involvement":["Epilepsy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in all","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enhanced","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":{"neutrophil":"2.3"},"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Spleen - Endothelial cells","Testis - Spermatogonia","Thyroid gland - Thyroid glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Astrocytes and Neuropil":"9918075.5","Capillaries":"5171129.0","Microglia and Neuropil":"11695109.9","Neurons":"8742554.3"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"cerebral cortex":"20055095.0"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA068798"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: Neutrophils - Protein binding","Tissue expression cluster":"Cluster 73: Brain - Neuronal signaling","Brain expression cluster":"Cluster 53: Neurons - Mixed function","Cell line expression cluster":"Cluster 5: Rhabdoid - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":43,"Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA068798":null},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.80e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.27e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.51e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.20e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.12e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.44e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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type enrichment":["Testis - Early spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.61e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.24e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.85e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.62e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.19e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.27e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential 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type specificity score":"7","RNA single cell type specific nCPM":{"Astrocytes":"14.9","Bergmann glia":"14.0","Brain excitatory neurons":"14.2","Brain inhibitory neurons":"14.8","Choroid plexus epithelial cells":"18.2","Ependymal cells":"13.6","Microglia":"13.1","Oligodendrocyte progenitor cells":"15.2","Oligodendrocytes":"15.3","Other brain neurons":"15.4"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"8","RNA single cell type group specific nCPM":{"Ciliated cells":"18.2","Glial cells":"15.3","Neuronal cells":"15.4"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in 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specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA071231"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 61: Non-specific - Transcription","Brain expression cluster":"Cluster 16: 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Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.76e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.39e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.72e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.02e-2"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.46e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.16e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic 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specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Adipose progenitor cells","Minor Salivary Gland - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group 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specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"38.5","Glial cells":"37.9","Neuronal cells":"18.9"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low 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mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Neurons":"9291730.6","T-cells":"8869213.5"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"22499","Protein tissue specific Intensity":{"fallopian tube":"1427026.0","lymphoid tissue":"3072762.3"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA028606"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli","Mitotic chromosome","Basal body"],"Secretome location":null,"Secretome function":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Non-specific - Cell proliferation","Tissue expression cluster":"Cluster 44: Bone marrow - Nuclear processes","Brain expression cluster":"Cluster 26: Oligodendrocytes - Mixed function","Cell line expression cluster":"Cluster 45: Non-specific - Nuclear processes","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":164,"Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm","Mitotic chromosome","Basal 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Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.41e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.22e-3"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.72e-3"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.86e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.03e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.60e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic 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single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific 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specific nCPM":{"Ciliated cells":"1.5","Glial cells":"1.3"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in some","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in some","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in some","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Stomach Adenocarcinoma (TCGA)":"3.8"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":"247","Protein cell type specific Intensity":{"Capillaries":"29348.4","Cardiomyocytes":"11897.0","Skeletal myofibers":"32751.5"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"1758","Protein tissue specific Intensity":{"heart muscle":"175831.2"},"Spatial region specificity":null,"Antibody":["HPA027813","HPA028676"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Golgi apparatus","Vesicles","Plasma membrane","Primary cilium","Primary cilium tip","Basal body"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 15: NK-cells - Unknown function","Tissue expression cluster":"Cluster 16: Liver & Kidney - Metabolism","Brain expression cluster":"Cluster 34: Non-specific - Mixed function","Cell line expression cluster":"Cluster 37: Non-specific - mRNA processing","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":6,"Subcellular main location":["Golgi apparatus","Vesicles","Plasma 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.25e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.46e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.89e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.75e-1"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"7.50e-4"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.29e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.62e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":null},{"Gene":"RTEL1","Gene synonym":["bK3184A7.3","C20orf41","DKFZP434C013","KIAA1088","NHL","RTEL"],"Ensembl":"ENSG00000258366","Gene description":"Regulator of telomere elongation helicase 1","Uniprot":["Q9NZ71"],"Chromosome":"20","Position":"63657810-63696253","Protein class":["Disease related genes","Enzymes","Essential proteins","Human disease related genes","Plasma proteins","Potential drug targets","Predicted intracellular proteins"],"Biological process":["DNA damage","DNA repair"],"Molecular 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nTPM":{"Myeloma":"24.9"},"RNA tissue cell type enrichment":["Skeletal muscle - Fibroblasts"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in many","Protein 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Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.16e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.56e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.10e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.99e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.71e-2"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.94e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.73e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.24e-2"}},{"Gene":"SARNP","Gene synonym":["CIP29","Hcc-1","THO1"],"Ensembl":"ENSG00000205323","Gene description":"SAP domain containing ribonucleoprotein","Uniprot":["P82979"],"Chromosome":"12","Position":"55752463-55817724","Protein class":["Essential proteins","Plasma proteins","Predicted intracellular proteins"],"Biological process":["mRNA transport","Transcription","Transcription regulation","Translation regulation","Transport"],"Molecular function":["DNA-binding","RNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA030902","HPA030903"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nuclear speckles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"11000","Blood expression cluster":"Cluster 42: Non-specific - Vesicular transport","Tissue expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 31: Non-specific - Transcription","Cell line expression cluster":"Cluster 38: Non-specific - Transcription","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":46,"Subcellular main location":["Nuclear speckles"],"Subcellular additional location":null,"Antibody RRID":{"HPA030902":"AB_10669872","HPA030903":"AB_10964180"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.08e-3"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.71e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.91e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.84e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.94e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.01e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.12e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.24e-5"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.10e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.49e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.73e-2"}},{"Gene":"SCARF1","Gene synonym":["KIAA0149","SREC","SREC1"],"Ensembl":"ENSG00000074660","Gene description":"Scavenger receptor class F member 1","Uniprot":["Q14162"],"Chromosome":"17","Position":"1633858-1645744","Protein class":["Predicted membrane proteins"],"Biological process":["Cell adhesion"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"61.5"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in 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brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":"11138","Protein cell type specific Intensity":{"Glomeruli":"878875.6","Macrophages":"1348761.1"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"lymphoid tissue":"310701.3"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA035108","HPA072936"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Golgi apparatus"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"790000","Blood expression cluster":"Cluster 38: Monocytes & Neutrophils - Degranulation","Tissue expression cluster":"Cluster 5: Spleen - Immune response","Brain expression cluster":"Cluster 28: Oligodendrocytes - Mixed function","Cell line expression cluster":"Cluster 48: Adipocytes & Endothelial cells - Angiogenesis","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":36,"Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA035108":"AB_10670289","HPA072936":"AB_2686559"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.93e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.88e-1"},"Cancer 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Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"200000","Blood expression cluster":"Cluster 25: Non-specific - Unknown function","Tissue expression cluster":"Cluster 70: Non-specific - Protein processing","Brain expression cluster":"Cluster 26: Oligodendrocytes - Mixed function","Cell line expression cluster":"Cluster 26: Non-specific - Mitochondria & RNA binding","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":14,"Subcellular main location":["Golgi apparatus"],"Subcellular additional location":null,"Antibody RRID":{"HPA020190":null,"HPA055760":"AB_2682910"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.19e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.58e-2"},"Cancer prognostics - 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protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Astrocytes":"27.7","Bergmann glia":"21.0","Brain excitatory neurons":"13.0","Brain inhibitory neurons":"13.0","Choroid plexus epithelial cells":"19.8","Ependymal cells":"10.4","Microglia":"16.0","Oligodendrocyte progenitor cells":"14.3","Oligodendrocytes":"18.8","Other brain neurons":"11.0"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Ciliated cells":"19.8","Glial cells":"27.7","Neuronal cells":"13.0"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes","Testis - Spermatogonia"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Neurons":"11911195.1"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"bone marrow":"8908925.1","lung":"8999937.3"},"Spatial region specificity":"Region enriched (niche group)","Antibody":["HPA060290"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nucleoli"],"Secretome location":null,"Secretome function":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 65: Brain - Transcription","Brain expression cluster":"Cluster 40: Astrocytes - Astrocyte-neuron interactions","Cell line expression cluster":"Cluster 42: Non-specific - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":206,"Subcellular main location":["Nucleoli"],"Subcellular additional location":["Nucleoplasm"],"Antibody RRID":{"HPA060290":"AB_2684244"},"Cancer prognostics - Bladder Urothelial 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specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region 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Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.66e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.67e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.74e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.16e-2"}},{"Gene":"SGMS1","Gene synonym":["MGC17342","MOB","SMS1","TMEM23"],"Ensembl":"ENSG00000198964","Gene description":"Sphingomyelin synthase 1","Uniprot":["Q86VZ5"],"Chromosome":"10","Position":"50305586-50625163","Protein class":["Enzymes","Housekeeping proteins","Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":["Apoptosis","Lipid metabolism","Sphingolipid metabolism"],"Molecular function":["Kinase","Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in all","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in all","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity 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specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":"643","Protein cell type specific Intensity":{"Collecting ducts":"101709.4","Distal tubules":"26911.8"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"674","Protein tissue specific Intensity":{"salivary gland":"67367.3"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA045191"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli fibrillar center","Golgi apparatus","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 12: Non-specific - Mitochondrial translation","Tissue expression cluster":"Cluster 69: Parathyroid gland - Mixed function","Brain expression cluster":"Cluster 11: White matter - Signal transduction","Cell line expression cluster":"Cluster 59: Leukemia - T-cell receptor","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nucleoli fibrillar center","Golgi apparatus","Cytosol"],"Antibody RRID":{"HPA045191":"AB_10959605"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic 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Rectum Adenocarcinoma (validation)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"9.58e-4"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.47e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.67e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.34e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.85e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.34e-1"}},{"Gene":"SHANK3","Gene synonym":["KIAA1650","prosap2","PSAP2","SPANK-2"],"Ensembl":"ENSG00000251322","Gene 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nCPM":{"Ciliated cells":"41.9","Endothelial cells":"45.7","Glial cells":"61.3","Neuronal cells":"71.5","Renal nephron cells":"37.0"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"296.9"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose visceral - Endothelial cells","Adrenal gland - Endothelial cells","Breast - Endothelial cells","Colon - Endothelial cells","Kidney - Endothelial cells","Liver - Vascular endothelial cells","Minor Salivary Gland - Endothelial cells","Pancreas - Endothelial cells","Prostate - Endothelial cells","Skeletal muscle - Endothelial cells","Skin - Endothelial cells","Spleen - Endothelial cells","Stomach - Endothelial cells","Testis - Endothelial cells"],"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":null,"Protein cell type distribution":null,"Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":null,"Protein tissue distribution":null,"Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA003446"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Plasma membrane"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 5: Spleen - Immune response","Brain expression cluster":"Cluster 51: Neurons - Mixed function","Cell line expression cluster":"Cluster 14: Myeloid leukemia - Innate immune response","Single cell expression 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nCPM":{"Choroid plexus epithelial cells":"63.7","Oligodendrocytes":"80.5"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"63.7","Glial cells":"80.5","Neuronal cells":"19.8","Secretory gland support":"23.6"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA 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Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.63e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.93e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.96e-3"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.82e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"7.84e-4"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.55e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic 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enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"liver":"100.5"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in all","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Colon - Enteric glia cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Neurons":"6270098.4"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"liver":"6278570.6"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA042001"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 3: Non-specific - Nuclear processes","Tissue expression cluster":"Cluster 31: Liver - Metabolism & Coagulation","Brain expression cluster":"Cluster 56: Hypothalamus - Neuropeptide signaling","Cell line expression cluster":"Cluster 31: Non-specific - Antiviral immune response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":53,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA042001":"AB_10794167"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"1.98e-4"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.82e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic 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- Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.02e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.85e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.13e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.50e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.71e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.18e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.11e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.05e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.26e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.23e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.55e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.75e-2"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic 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Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.66e-2"}},{"Gene":"SHROOM2","Gene synonym":["APXL"],"Ensembl":"ENSG00000146950","Gene description":"Shroom family member 2","Uniprot":["Q13796"],"Chromosome":"X","Position":"9786429-9949443","Protein class":["Plasma proteins","Predicted intracellular proteins"],"Biological process":null,"Molecular function":["Actin-binding","Developmental protein"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"retina":"19.3"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"178.4"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Prostate glandular cells","Skeletal muscle - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"cerebral cortex":"4936197.2"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA051646","HPA061435"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Plasma membrane","Cell Junctions","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 46: Brain & retina - Neuronal signaling","Brain expression cluster":"Cluster 53: Neurons - Mixed function","Cell line expression cluster":"Cluster 69: Skin cancer - ECM organization","Single cell expression cluster":"Cluster 85: Non-specific - Mixed 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nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"161.1"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected 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distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Granulosa cells":"39173056.4"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"liver":"41042996.2"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA003324","CAB017489","HPA071055","CAB079035"],"Reliability (IH)":"Enhanced","Reliability (Mouse Brain)":"Supported","Reliability (IF)":"Enhanced","Subcellular location":["Plasma membrane","Cell Junctions"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"15000","Blood expression cluster":"Cluster 9: T-regs - Cell cycle regulation","Tissue expression cluster":"Cluster 52: Non-specific - Cellular respiration","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line expression cluster":"Cluster 34: Testis cancer - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":55,"Subcellular main location":["Plasma membrane","Cell Junctions"],"Subcellular additional location":null,"Antibody RRID":{"CAB017489":null,"CAB079035":null,"HPA003324":"AB_1856982","HPA071055":"AB_2686337"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.30e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.01e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.38e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.28e-3"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.26e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.01e-2"}},{"Gene":"SLC25A51","Gene synonym":["CG7943","MCART1","MGC14836"],"Ensembl":"ENSG00000122696","Gene description":"Solute carrier family 25 member 51","Uniprot":["Q9H1U9"],"Chromosome":"9","Position":"37879400-37904353","Protein class":["Predicted membrane proteins","Transporters"],"Biological process":["Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Astrocytes":"22.6","Bergmann glia":"25.8","Brain excitatory neurons":"28.1","Brain inhibitory neurons":"29.9","Choroid plexus epithelial cells":"28.2","Ependymal cells":"14.1","Megakaryocytes":"11.7","Microglia":"20.7","Oligodendrocyte progenitor cells":"24.2","Oligodendrocytes":"28.4","Other brain neurons":"27.7"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"28.2","Glial cells":"28.4","Megakaryocytes":"11.7","Neuronal cells":"29.9"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"5","RNA blood cell specific nTPM":{"basophil":"16.7"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"5","RNA blood lineage specific nTPM":{"granulocytes":"16.7"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipocytes (Subcutaneous)","Adipose visceral - Adipocytes (Visceral)","Breast - Adipocytes (Breast)","Testis - Early spermatids","Testis - Late spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA046388"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Mitochondria"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Non-specific - Cell proliferation","Tissue expression cluster":"Cluster 44: Bone marrow - Nuclear processes","Brain expression cluster":"Cluster 14: Neurons - Synaptic function","Cell line expression cluster":"Cluster 43: Non-specific - Basic cellular processes","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":6,"Subcellular main location":["Mitochondria"],"Subcellular additional location":null,"Antibody RRID":{"HPA046388":"AB_2679649"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.47e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.64e-1"},"Cancer prognostics - Breast Invasive 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Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.07e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.68e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.73e-3"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.54e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"8.20e-6"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.33e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.67e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.20e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.04e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.98e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.58e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.76e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"3.13e-4"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.29e-1"}},{"Gene":"SLC30A1","Gene synonym":["ZNT1","ZRC1"],"Ensembl":"ENSG00000170385","Gene description":"Solute carrier family 30 member 1","Uniprot":["Q9Y6M5"],"Chromosome":"1","Position":"211571568-211579161","Protein class":["Housekeeping proteins","Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":["Antiport","Calcium transport","Copper transport","Ion transport","Transport","Zinc transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue 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rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"cerebral cortex":"3894854.9"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA015275","HPA049000"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Vesicles","Plasma membrane"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Vesicular 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regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Pancreas epithelial cells":"35973076.1"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"Stomach":"9476219.7"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA042430"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Uncertain","Subcellular location":["Vesicles","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Non-specific - Cell proliferation","Tissue expression cluster":"Cluster 38: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 50: Non-specific - Nucleic acid binding","Cell line expression cluster":"Cluster 63: Non-specific - Protein processing","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":34,"Subcellular main location":["Vesicles","Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA042430":"AB_10806238"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.81e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.37e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.72e-2"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.66e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.53e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.43e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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5","Uniprot":["Q8WUX1"],"Chromosome":"X","Position":"48458537-48470260","Protein class":["Metabolic proteins","Predicted membrane proteins","Transporters"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in many","RNA tissue specificity score":"4","RNA tissue specific nTPM":{"pancreas":"223.8"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Erythrocyte progenitors":"94.9","Pancreatic acinar cells":"124.4","Plasma cells":"88.9"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Acinar cells":"124.4","Erythrocytes":"94.9","Plasma cells":"88.9"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"24","RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"326.1"},"RNA single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in some","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":{"TFAP2B+ Inhibitory":"13.1"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"Myeloma":"246.7"},"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Stomach - Chief cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":"39576","Protein cell type specific Intensity":{"Pancreas epithelial cells":"4993217.9","Pancreatic islets":"2922017.8"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"401686","Protein tissue specific Intensity":{"pancreas":"35955527.9","Stomach":"44381588.8"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA047411"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 5: Non-specific - Cell proliferation","Tissue expression cluster":"Cluster 8: Pancreas - Proteolysis","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line expression cluster":"Cluster 51: Myeloma - Immunoglobulins","Single cell expression cluster":"Cluster 85: Non-specific - Mixed 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.50e-3"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"4.92e-4"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.05e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.21e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"validated prognostic","is_prognostic":true,"p_val":"1.46e-8"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"unfavorable","prognostic":"validated prognostic","is_prognostic":true,"p_val":"3.10e-6"},"Cancer 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tissue specific nTPM":{"esophagus":"52.1"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":"13","RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"1052.0"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer 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all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Adrenal cortex cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"salivary gland":"317715.4"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA039721","HPA077838"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 13: Non-specific - Mitochondria","Tissue expression cluster":"Cluster 11: Esophagus - Basic cellular processes","Brain expression cluster":"Cluster 49: Hindbrain - Mixed function","Cell line expression cluster":"Cluster 13: Non-specific - Mixed function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":210,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA039721":"AB_10672893","HPA077838":null},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.86e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.78e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.10e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.21e-3"},"Cancer 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distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":"22","RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"972.2"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Skin Cutaneous Melanoma (TCGA)":"327.6"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Immune cell enriched","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"plasmacytoid DC":"17.2"},"RNA blood lineage specificity":"Lineage enriched","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":"10","RNA blood lineage specific nTPM":{"dendritic cells":"17.2"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Sertoli cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Astrocytes and Neuropil":"11314260.4","Granulosa cells":"5211110.4","Microglia and Neuropil":"13048352.7","Neurons":"6310997.3"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"cerebral cortex":"9198948.9"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA052673","HPA056077"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Vesicles","Plasma membrane","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"76000","Blood expression cluster":"Cluster 44: Plasmacytoid DCs - Plasma membrane proteins","Tissue expression cluster":"Cluster 3: Oligodendrocytes - Myelination","Brain expression cluster":"Cluster 19: Astrocytes - Mixed function","Cell line expression cluster":"Cluster 53: Squamous epithelial cells - Keratinization","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":45,"Subcellular main location":["Plasma membrane","Cytosol"],"Subcellular additional location":["Vesicles"],"Antibody RRID":{"HPA052673":"AB_2681909","HPA056077":"AB_2683031"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.29e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.70e-3"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.80e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.60e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.42e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.56e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.18e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.40e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.15e-3"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.11e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"validated prognostic","is_prognostic":true,"p_val":"9.58e-9"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"unfavorable","prognostic":"validated prognostic","is_prognostic":true,"p_val":"6.51e-5"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"6.71e-4"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.22e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.87e-1"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.76e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.57e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.18e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.06e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.38e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.81e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.59e-2"},"Cancer 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.05e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.27e-3"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.44e-2"}},{"Gene":"SLCO1A2","Gene synonym":["OATP","OATP-A","OATP1A2","SLC21A3"],"Ensembl":"ENSG00000084453","Gene description":"Solute carrier organic anion transporter family member 1A2","Uniprot":["P46721"],"Chromosome":"12","Position":"21264600-21419594","Protein class":["Metabolic proteins","Plasma proteins","Predicted intracellular proteins","Predicted membrane proteins","Transporters"],"Biological process":["Ion transport","Lipid transport","Transport"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"15.0","choroid plexus":"7.0","liver":"7.5","salivary gland":"14.6"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"8","RNA single cell type specific nCPM":{"Oligodendrocytes":"541.5","Retinal pigment epithelial cells":"232.8"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"10","RNA single cell type group specific nCPM":{"Glial cells":"541.5","Pigment cells":"232.8"},"RNA single nuclei brain specificity":"Group enriched","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":"9","RNA single nuclei brain specific nCPM":{"Oligodendrocytes":"730.6","Vascular endothelial cells":"806.8"},"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Testicular Germ Cell Tumor (TCGA)":"25.5"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in single","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Lung - Alveolar cells type 1","Spleen - B-cells (Spleen)"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Astrocytes and Neuropil":"14870.0","Hepatocytes":"6546.8"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region group enriched","Antibody":["HPA071152"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Plasma membrane"],"Secretome location":null,"Secretome function":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: Neutrophils - Unknown function","Tissue expression cluster":"Cluster 36: Brain & Liver - Signaling","Brain expression cluster":"Cluster 11: White matter - Signal transduction","Cell line expression cluster":"Cluster 56: Non-specific - Sensory perception","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":["Plasma membrane"],"Subcellular additional location":null,"Antibody RRID":{"HPA071152":"AB_2686350"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.27e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.32e-3"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.03e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.78e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.54e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"5.43e-4"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.50e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.28e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.09e-2"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.29e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.31e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.64e-3"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.62e-2"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.77e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.19e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.67e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.11e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.15e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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(TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.61e-1"}},{"Gene":"SLX1A","Gene synonym":["GIYD1"],"Ensembl":"ENSG00000132207","Gene description":"SLX1 homolog A, structure-specific endonuclease subunit","Uniprot":["Q9BQ83"],"Chromosome":"16","Position":"30193875-30197561","Protein class":["Predicted intracellular proteins"],"Biological process":["DNA damage","DNA recombination","DNA repair"],"Molecular function":["Endonuclease","Hydrolase","Nuclease"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Astrocytes":"6.0","Bergmann glia":"4.8","Brain excitatory neurons":"3.4","Brain inhibitory neurons":"2.7","Choroid plexus epithelial cells":"1.5","Ependymal cells":"2.2","Microglia":"7.2","Oligodendrocyte progenitor cells":"6.0","Oligodendrocytes":"8.2","Other brain neurons":"3.8"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"5","RNA single cell type group specific nCPM":{"Ciliated cells":"2.2","Glial cells":"8.2","Neuronal cells":"3.8"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"878","Protein cell type specific Intensity":{"Oocytes":"87774.9"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA047038"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 25: Non-specific - Unknown function","Tissue expression cluster":"Cluster 68: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 6: Non-specific - Immune response","Cell line expression cluster":"Cluster 54: Non-specific - Transcription","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":11,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA047038":"AB_2679913"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.53e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.75e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.54e-3"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.66e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.52e-3"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.27e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":null,"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.45e-1"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.06e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.43e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.51e-2"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.02e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.47e-1"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.39e-1"},"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.95e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.11e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.46e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.55e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.27e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.71e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.17e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.52e-2"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.78e-1"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic 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single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region 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specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA009065"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles","Golgi apparatus"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 11: Esophagus - Basic cellular processes","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line 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cells":"126.4","Oligodendrocytes":"119.9","Other brain neurons":"114.8"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"8","RNA single cell type group specific nCPM":{"Ciliated cells":"249.8","Glial cells":"270.9","Neuronal cells":"147.9"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain 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Spermatocytes","Thyroid gland - Thyroid glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA070614"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Actin filaments"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 42: Non-specific - Vesicular transport","Tissue expression cluster":"Cluster 21: Testis - Mixed function","Brain expression cluster":"Cluster 25: Non-specific - Transcription","Cell line expression cluster":"Cluster 60: Prostate cancer - Unknown 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synonym":["C1orf64","ERRF","MGC24047"],"Ensembl":"ENSG00000183888","Gene description":"Steroid receptor associated and regulated protein","Uniprot":["Q8NEQ6"],"Chromosome":"1","Position":"16004236-16008807","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in some","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"brain":"6.9","breast":"4.8"},"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"5","RNA single cell type specific nCPM":{"Breast hormone-responsive cells":"48.8","Conjunctival goblet cells":"75.7","Epididymal clear cells":"94.2","Respiratory ionocytes":"65.2","Salivary duct cells":"25.5"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"9","RNA single cell type group specific nCPM":{"Ductal cells":"25.5","Goblet cells":"75.7","Ionocytes":"65.2","Luminal cells":"48.8","Reproductive supporting cells":"94.2"},"RNA single nuclei brain specificity":"Cell type enriched","RNA single nuclei brain distribution":"Detected in some","RNA single nuclei brain specificity score":"9","RNA single nuclei brain specific nCPM":{"Vascular endothelial cells":"78.1"},"RNA single nuclei brain neurons specificity":"Not detected","RNA single nuclei brain neurons distribution":"Not detected","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Group enriched","RNA cancer distribution":"Detected in some","RNA cancer 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distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA026676"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: Neutrophils - Protein binding","Tissue expression cluster":"Cluster 3: Oligodendrocytes - Myelination","Brain expression cluster":"Cluster 47: Endothelial cells - Vasculature","Cell line expression cluster":"Cluster 27: Breast cancer - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":8,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA026676":"AB_1853866"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.92e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.97e-2"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.79e-3"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.36e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.51e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":null,"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":null,"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":null,"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":null,"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.51e-1"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.27e-2"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":null,"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":null,"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":null,"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.71e-3"}},{"Gene":"SRCAP","Gene synonym":["DOMO1","KIAA0309","SWR1"],"Ensembl":"ENSG00000080603","Gene description":"Snf2 related CREBBP activator protein","Uniprot":["Q6ZRS2"],"Chromosome":"16","Position":"30698209-30741409","Protein class":["Disease related genes","Essential proteins","Human disease related genes","Predicted intracellular proteins"],"Biological process":["Host-virus interaction","Transcription","Transcription regulation"],"Molecular function":["Activator","Chromatin regulator","DNA-binding","Hydrolase"],"Disease involvement":["Disease variant","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Low cell type specificity","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":null,"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA028929"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Nuclear bodies","Golgi apparatus"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Dendritic cells - Unknown function","Tissue expression cluster":"Cluster 63: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 4: Non-specific - mRNA splicing & Cell cycle","Cell line expression cluster":"Cluster 54: Non-specific - Transcription","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":58,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Nuclear bodies","Golgi apparatus"],"Antibody RRID":{"HPA028929":"AB_10601265"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.91e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.80e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.14e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.99e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.73e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.41e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.28e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.66e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.20e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.58e-3"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential 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Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.30e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.60e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.90e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.16e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.24e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.27e-3"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic 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Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.92e-2"}},{"Gene":"ST3GAL3","Gene synonym":["MRT12","SIAT6"],"Ensembl":"ENSG00000126091","Gene description":"ST3 beta-galactoside alpha-2,3-sialyltransferase 3","Uniprot":["Q11203"],"Chromosome":"1","Position":"43705824-43931165","Protein class":["Disease related genes","Enzymes","Human disease related genes","Metabolic proteins","Potential drug targets","Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":["Glycosyltransferase","Transferase"],"Disease involvement":["Disease variant","Epilepsy","Intellectual disability"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"skeletal muscle":"82.4","tongue":"77.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Astrocytes":"118.1","Bergmann glia":"95.1","Brain excitatory neurons":"133.1","Brain inhibitory neurons":"150.3","Choroid plexus epithelial cells":"180.8","Ependymal cells":"138.1","Microglia":"123.2","Oligodendrocyte progenitor cells":"102.2","Oligodendrocytes":"103.6","Other brain neurons":"134.2"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"4","RNA single cell type group specific nCPM":{"Ciliated cells":"180.8","Glial cells":"123.2","Neuronal cells":"150.3"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Liver - Hepatocytes","Testis - Early spermatids","Testis - Late spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Granulosa cells":"983094.5","Neurons":"1251024.0"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"307","Protein tissue specific Intensity":{"liver":"30736.8"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA051102"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Intracellular and membrane","Secretome function":"Enzyme","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 24: Non-specific - Transcription","Tissue expression cluster":"Cluster 25: Non-specific - Basic cellular processes","Brain expression cluster":"Cluster 38: Sub-cortical - Mixed function","Cell line expression cluster":"Cluster 14: Myeloid leukemia - Innate immune response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":4,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA051102":"AB_2681344"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.12e-3"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.61e-1"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.16e-3"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.79e-1"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.52e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.99e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.39e-2"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic 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brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Neurons":"679585.5"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA051855"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.90e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.88e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.19e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.54e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.47e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.44e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.43e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.20e-1"}},{"Gene":"STRADA","Gene synonym":["LYK5","NY-BR-96","Stlk","STRAD"],"Ensembl":"ENSG00000266173","Gene description":"STE20 related adaptor alpha","Uniprot":["Q7RTN6"],"Chromosome":"17","Position":"63682336-63741986","Protein class":["Disease related genes","Enzymes","Human disease related genes","Potential drug targets","Predicted intracellular proteins"],"Biological process":["Cell cycle"],"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity 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nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Adipose progenitor cells","Testis - Early spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Fallopian tube cells":"1601024.1"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"cerebral cortex":"1296338.0","fallopian tube":"2189900.1","kidney":"700275.6","lymphoid tissue":"2319969.8"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA031637"],"Reliability (IH)":"Approved","Reliability (Mouse 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Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.04e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.20e-3"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.18e-3"},"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.47e-2"},"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.23e-3"},"Cancer prognostics - Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.11e-2"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic 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specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Astrocytes and Neuropil":"5296558.3","Microglia and Neuropil":"4425520.8"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"cerebral cortex":"12358172.0"},"Spatial region specificity":"Region 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process":["Catecholamine metabolism","Lipid metabolism","Steroid metabolism"],"Molecular function":["Transferase"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in all","RNA tissue specificity score":"5","RNA tissue specific nTPM":{"intestine":"225.7"},"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"3.8","Glial cells":"6.6","Neuronal cells":"3.8"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Group enriched","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":"10","RNA blood cell specific nTPM":{"classical monocyte":"64.6","intermediate monocyte":"55.7","myeloid DC":"35.2","non-classical monocyte":"26.8"},"RNA blood lineage specificity":"Group enriched","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":"11","RNA blood lineage specific nTPM":{"dendritic cells":"35.2","monocytes":"64.6"},"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enriched (niche group)","Antibody":["HPA049500","HPA051051"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"270000","Blood expression cluster":"Cluster 26: Monocytes - Plasma membrane proteins","Tissue expression cluster":"Cluster 7: Small intestine - Absorption and Digestion","Brain expression cluster":"Cluster 48: Non-specific - Mixed function","Cell line expression cluster":"Cluster 18: Liver cancer - Metabolism","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":{"HPA049500":"AB_2680796","HPA051051":"AB_2681327"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.45e-3"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.50e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.77e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"2.73e-4"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.44e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.31e-2"},"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.19e-3"},"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.33e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.43e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.66e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.34e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.61e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.58e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential 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level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Glial cells":"19.1","Neuronal cells":"10.5"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adipose subcutaneous - Endothelial cells","Heart muscle - Endothelial cells","Kidney - Endothelial cells","Skeletal muscle - Endothelial cells","Thyroid gland - T-cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"B-cells":"31400640.4","Macrophages":"34778030.2","T-cells":"37450295.7"},"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"lung":"10390490.9","lymphoid tissue":"18766411.3"},"Spatial region specificity":"Broadly 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nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Testis - Spermatocytes"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"heart muscle":"3960923.8"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA038593","HPA038594"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":"26000","Blood expression cluster":null,"Tissue expression cluster":"Cluster 48: Ciliated tissues - Cilium organization","Brain expression cluster":"Cluster 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.53e-2"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.78e-2"}},{"Gene":"TCP10L","Gene synonym":["PRED77"],"Ensembl":"ENSG00000242220","Gene description":"T-complex 10 like","Uniprot":["Q8TDR4"],"Chromosome":"21","Position":"32497967-32587373","Protein class":["Predicted intracellular proteins"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["Repressor"],"Disease involvement":["Tumor suppressor"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"8","RNA tissue specific nTPM":{"testis":"142.6"},"RNA single cell 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pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Prostate - Fibroblasts","Stomach - Fibroblasts"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"145","Protein cell type specific Intensity":{"Macrophages":"14470.8"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"lymphoid tissue":"131421.7"},"Spatial region specificity":"Region enriched (niche group)","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 40: Monocytes - Innate immune response","Tissue expression cluster":"Cluster 5: Spleen - Immune response","Brain expression cluster":"Cluster 19: Astrocytes - Mixed function","Cell line expression cluster":"Cluster 21: Lymphoma - Adaptive immune response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed 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distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Adrenal gland - Fibroblasts","Breast - Endothelial cells","Spleen - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Glomeruli":"310297412.2"},"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in all","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA001636","HPA001637","CAB010822"],"Reliability (IH)":"Enhanced","Reliability (Mouse 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single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"23.8","Erythrocytes":"42.4","Glial cells":"72.5","Myocytes":"32.0","Neuronal cells":"40.9","Pigment cells":"26.3"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":{"Liver Hepatocellular Carcinoma (TCGA)":"19.4"},"RNA brain regional specificity":"Low region 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Salivary Gland - Minor salivary glandular cells","Prostate - Smooth muscle cells","Testis - Sertoli cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Hepatocytes":"1652513.3"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"1989","Protein tissue specific Intensity":{"cerebral cortex":"104793.4","liver":"383920.4","salivary gland":"108000.6"},"Spatial region specificity":"Region enriched (single niche)","Antibody":["HPA046762"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"No","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 45: Liver - Metabolism & Coagulation","Brain expression 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Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.25e-2"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.71e-3"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.16e-1"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.68e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.55e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.87e-1"}},{"Gene":"TMEM265","Gene synonym":[],"Ensembl":"ENSG00000281991","Gene description":"Transmembrane protein 265","Uniprot":["A0A087WTH1"],"Chromosome":"16","Position":"30740642-30745196","Protein class":["Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at transcript level","HPA evidence":"Evidence at transcript level","UniProt evidence":"No human protein\/transcript evidence","NeXtProt evidence":"Evidence at transcript level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Group enriched","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":"17","RNA single cell type specific nCPM":{"Astrocytes":"9.3","Bergmann glia":"7.7","Brain excitatory neurons":"7.4","Brain inhibitory neurons":"7.4","Choroid plexus epithelial cells":"8.7","Ependymal cells":"7.3","Microglia":"11.8","Oligodendrocyte progenitor cells":"5.8","Oligodendrocytes":"10.4","Other brain neurons":"5.7"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"20","RNA single cell type group specific nCPM":{"Ciliated cells":"8.7","Glial cells":"11.8","Neuronal cells":"7.4"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Not detected","RNA brain regional distribution":"Not detected","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Not detected","RNA brain domain distribution":"Not detected","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"head and neck cancer":"27.6"},"RNA tissue cell type enrichment":["Lung - Alveolar cells type 2","Minor Salivary Gland - Minor salivary glandular cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":null,"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 21: Neutrophils - Unknown function","Tissue expression cluster":"Cluster 58: Skin - Keratinization","Brain expression cluster":null,"Cell line expression cluster":"Cluster 53: Squamous epithelial cells - Keratinization","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":null,"Subcellular main location":null,"Subcellular additional location":null,"Antibody RRID":null,"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.82e-1"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.10e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":null,"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.76e-2"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.02e-2"},"Cancer prognostics - Colon Adenocarcinoma (validation)":null,"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":null,"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic 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type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.63e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.28e-3"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.81e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.27e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.38e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"7.12e-4"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":null,"Cancer 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specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"86.7","Glial cells":"54.1","Neuronal cells":"49.2"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.79e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.29e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.66e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.49e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.75e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.54e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.33e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.36e-1"}},{"Gene":"TNFRSF6B","Gene synonym":["DcR3","M68","TR6"],"Ensembl":"ENSG00000243509","Gene description":"TNF receptor superfamily member 6b","Uniprot":["O95407"],"Chromosome":"20","Position":"63696652-63698684","Protein class":["Predicted secreted proteins"],"Biological process":["Apoptosis"],"Molecular function":["Receptor"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type 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rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":null,"Antibody":["HPA047154"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":null,"Subcellular location":null,"Secretome location":"Secreted to blood","Secretome function":"Receptor","CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":406000,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 44: Plasmacytoid DCs - Plasma membrane proteins","Tissue expression cluster":"Cluster 5: 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- Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 2: Dendritic cells - Unknown function","Tissue expression cluster":"Cluster 1: Choroid plexus - Transmembrane transport","Brain expression cluster":"Cluster 44: Non-specific - Mixed function","Cell line expression cluster":"Cluster 55: Lymphoma - Immune response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":4,"Subcellular main location":["Cytosol"],"Subcellular additional location":null,"Antibody RRID":{"HPA035437":"AB_10672092","HPA046721":"AB_2732531"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.95e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.55e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic 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brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"207","Protein cell type specific Intensity":{"Neurons":"20685.8"},"Protein tissue specificity":"Not detected","Protein tissue 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mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enriched","Protein cell type distribution":"Detected in single","Protein cell type specificity score":"26860","Protein cell type specific Intensity":{"Oocytes":"2685997.2"},"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region group 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- Lung Adenocarcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"validated prognostic","is_prognostic":true,"p_val":"1.88e-5"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"unfavorable","prognostic":"validated prognostic","is_prognostic":true,"p_val":"1.41e-6"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.89e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.98e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.96e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.05e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic 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specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type enhanced","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":{"Skeletal 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.65e-1"},"Cancer prognostics - Colon Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.23e-3"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.69e-3"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"4.04e-4"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.54e-3"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.60e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential 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specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in all","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage 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regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in all","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enhanced","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"skin":"9192787.9"},"Spatial region specificity":"Region enriched (niche group)","Antibody":["HPA038701"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood 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specificity":"Group enriched","RNA single nuclei brain neurons distribution":"Detected in some","RNA single nuclei brain neurons specificity score":"5","RNA single nuclei brain neurons specific nCPM":{"Cerebellar Purkinje cells":"7.1","Forebrain projection neurons":"11.3","Other Excitatory neurons":"9.5"},"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enhanced","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":{"colorectal cancer":"10.1"},"RNA tissue cell type enrichment":["Breast - Breast glandular cells","Colon - Enteric glia cells","Lung - Alveolar cells type 2","Testis - Early spermatids","Testis - Late spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Not detected","RNA mouse brain regional distribution":"Not detected","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Not detected","RNA rat brain regional distribution":"Not detected","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":"23329","Protein cell type specific Intensity":{"Alveolar cell types":"1405658.5","Collecting ducts":"2679108.5","Distal tubules":"1392293.1","Fallopian tube cells":"3854429.2"},"Protein tissue specificity":"Group enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":"15374","Protein tissue specific Intensity":{"fallopian tube":"1674726.3","Stomach":"1400047.3"},"Spatial region 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Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.29e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":null,"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)":null,"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)":null,"Cancer prognostics - Lung Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.27e-3"},"Cancer prognostics - Lung Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.04e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.27e-3"},"Cancer 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specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Low tissue specificity","Protein tissue distribution":"Detected in many","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA028490"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 35: Neutrophils - Protein binding","Tissue expression cluster":"Cluster 61: Non-specific - Transcription","Brain expression cluster":"Cluster 6: Non-specific - Immune response","Cell line expression cluster":"Cluster 71: Lymphoma - Inflammatory response","Single cell expression cluster":"Cluster 85: Non-specific - Mixed 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.63e-3"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.08e-1"},"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.85e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.33e-2"},"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"7.31e-4"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"4.16e-4"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic 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synonym":["ZCW2"],"Ensembl":"ENSG00000206559","Gene description":"Zinc finger CW-type and PWWP domain containing 2","Uniprot":["Q504Y3"],"Chromosome":"3","Position":"28348721-28538122","Protein class":["Predicted intracellular proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at transcript level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enhanced","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":{"testis":"9.3"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Astrocytes":"71.1","Bergmann glia":"55.8","Brain excitatory neurons":"48.8","Brain inhibitory neurons":"48.9","Choroid plexus epithelial cells":"60.8","Early spermatids":"42.3","Ependymal cells":"58.4","Late primary spermatocytes":"138.8","Oligodendrocyte progenitor cells":"51.9","Oligodendrocytes":"41.3","Other brain neurons":"40.8"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":"5","RNA single cell type group specific nCPM":{"Ciliated cells":"60.8","Glial cells":"71.1","Neuronal cells":"48.9","Spermatogenic cell types":"138.8"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in many","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in some","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in single","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Not detected","RNA cell line distribution":"Not detected","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Skeletal muscle - Skeletal myocytes","Testis - Early spermatids"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in many","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA035035","HPA039839"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nuclear speckles"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 46: Basophils - Proteolysis","Tissue expression cluster":"Cluster 61: Non-specific - Transcription","Brain expression cluster":"Cluster 9: Non-specific - 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"4.56e-1"},"Cancer prognostics - Glioblastoma Multiforme (TCGA)":null,"Cancer prognostics - Glioblastoma Multiforme (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.48e-1"},"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)":null,"Cancer prognostics - Kidney Chromophobe (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.88e-2"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.63e-1"},"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.56e-1"},"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)":{"prognostic type":"favorable","prognostic":"potential 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single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"11.7","Glial cells":"7.7","Neuronal cells":"5.8"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA047232"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nucleoli","Nucleoli rim","Plasma membrane"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - DNA binding","Tissue expression cluster":"Cluster 64: Non-specific - Transcription","Brain expression cluster":"Cluster 6: Non-specific - Immune response","Cell line expression cluster":"Cluster 40: Non-specific - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":14,"Subcellular main 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Rectum Adenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.01e-1"},"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.14e-2"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"7.59e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.92e-1"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":{"prognostic type":"unfavorable","prognostic":"potential prognostic","is_prognostic":true,"p_val":"4.34e-4"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.93e-1"}},{"Gene":"ZIC1","Gene synonym":["ZIC","ZNF201"],"Ensembl":"ENSG00000152977","Gene description":"Zic family member 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nCPM":{"Bergmann glia":"636.6","Ependymal cells":"293.0"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"293.0","Glial cells":"636.6","Neuronal cells":"147.3"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in all","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":{"Cerebellar granular cells":"537.6","Upper rhombic lip-derived neurons":"495.1"},"RNA cancer specificity":"Cancer enhanced","RNA cancer distribution":"Detected in many","RNA cancer specificity 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line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Region enriched","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":"4","RNA macaque brain regional specific nTPM":{"cerebellum":"442.4"},"RNA mouse brain regional specificity":"Region enhanced","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":{"cerebellum":"293.6"},"RNA pig brain regional specificity":"Region enriched","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":"5","RNA pig brain regional specific nTPM":{"cerebellum":"533.6"},"RNA rat brain regional specificity":"Region enhanced","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":{"cerebellum":"483.3"},"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"139","Protein tissue specific Intensity":{"salivary gland":"13919.3"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA004098"],"Reliability (IH)":"Supported","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 71: Cerebellum - Nervous system development","Brain expression cluster":"Cluster 35: Non-specific - DNA binding","Cell line expression cluster":"Cluster 5: Rhabdoid - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":118,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":null,"Antibody RRID":{"HPA004098":"AB_1859065"},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":null,"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.90e-2"},"Cancer prognostics - Breast Invasive Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.67e-1"},"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.16e-1"},"Cancer prognostics - Colon Adenocarcinoma (TCGA)":null,"Cancer prognostics - Colon Adenocarcinoma (validation)":null,"Cancer prognostics - Glioblastoma Multiforme (TCGA)":{"prognostic 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Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.08e-1"},"Cancer prognostics - Lung Adenocarcinoma (validation)":null,"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.06e-1"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.93e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.80e-1"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.44e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":null,"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":null,"Cancer prognostics - Prostate Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (TCGA)":null,"Cancer prognostics - Rectum Adenocarcinoma (validation)":null,"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.98e-1"},"Cancer prognostics - Stomach Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"6.19e-2"},"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"9.92e-2"},"Cancer prognostics - Thyroid Carcinoma (TCGA)":null,"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"8.96e-2"}},{"Gene":"ZIC3","Gene synonym":["HTX","HTX1","ZNF203"],"Ensembl":"ENSG00000156925","Gene description":"Zic family member 3","Uniprot":["O60481"],"Chromosome":"X","Position":"137566127-137577691","Protein class":["Disease related genes","Human disease related genes","Predicted intracellular proteins","Transcription factors"],"Biological process":["Differentiation","Neurogenesis","Transcription","Transcription regulation"],"Molecular function":["Activator","Developmental protein","DNA-binding"],"Disease involvement":["Disease variant","Heterotaxy"],"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Tissue enriched","RNA tissue distribution":"Detected in some","RNA tissue specificity score":"7","RNA tissue specific nTPM":{"brain":"17.7"},"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Bergmann glia":"24.4"},"RNA single cell type group specificity":"Group enriched","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":"5","RNA single cell type group specific nCPM":{"Glial cells":"24.4","Neuronal cells":"6.7"},"RNA single nuclei brain specificity":"Cell type enhanced","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":{"Bergmann glia":"27.7","Vascular endothelial cells":"27.1"},"RNA single nuclei brain neurons specificity":"Cell type enhanced","RNA single nuclei brain neurons distribution":"Detected in some","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":{"Cerebellar granular cells":"12.2","Cholinergic":"13.3","Upper rhombic lip-derived neurons":"11.4"},"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in single","RNA cancer specificity score":"11","RNA cancer specific pTPM":{"Testicular Germ Cell Tumor (TCGA)":"8.9"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Domain enhanced","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":{"cerebellar cortex":"28.3"},"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Cancer enriched","RNA cell line distribution":"Detected in some","RNA cell line specificity score":"9","RNA cell line specific nTPM":{"testis cancer":"22.8"},"RNA tissue cell type enrichment":["Pituitary gland - Fibroblasts","Testis - Spermatogonia"],"RNA macaque brain regional 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type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA069523"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":null,"Tissue expression cluster":"Cluster 27: Cerebellum - Synaptic function","Brain expression cluster":"Cluster 15: Non-specific - Transcription","Cell line expression cluster":"Cluster 34: Testis cancer - Unknown function","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":2,"Subcellular main 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specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Low cell type specificity","Protein cell type distribution":"Detected in many","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"fallopian tube":"363878.7"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA006672"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Nuclear bodies","Mitochondria"],"Secretome location":null,"Secretome function":null,"CCD Protein":"Yes","CCD Transcript":"No","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 30: Non-specific - DNA binding","Tissue expression 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(validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.65e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.45e-2"},"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.29e-2"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"3.87e-3"},"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"2.80e-1"},"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"5.05e-2"},"Cancer prognostics - Pancreatic Adenocarcinoma (validation)":{"prognostic 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(TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.29e-1"},"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.09e-1"}},{"Gene":"ZMYM6","Gene synonym":["Buster2","KIAA1353","MYM","ZBED7","ZNF198L4","ZNF258"],"Ensembl":"ENSG00000163867","Gene description":"Zinc finger MYM-type containing 6","Uniprot":["O95789"],"Chromosome":"1","Position":"34986165-35031945","Protein class":["Predicted intracellular proteins","Predicted membrane proteins"],"Biological process":null,"Molecular function":null,"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in all","RNA tissue specificity score":null,"RNA tissue specific 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level","UniProt evidence":"Evidence at protein level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Cell type enhanced","RNA single cell type distribution":"Detected in many","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":{"Astrocytes":"14.7","Bergmann glia":"19.8","Brain excitatory neurons":"18.6","Brain inhibitory neurons":"16.1","Choroid plexus epithelial cells":"22.5","Ependymal cells":"14.9","Oligodendrocyte progenitor cells":"18.3","Oligodendrocytes":"19.3","Other brain neurons":"14.8"},"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in many","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"22.5","Glial 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score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Not detected in immune cells","RNA blood cell distribution":"Not detected","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Not detected","RNA blood lineage distribution":"Not detected","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":["Spleen - Endothelial cells"],"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":"5119","Protein cell type specific Intensity":{"Astrocytes and Neuropil":"576518.6","Microglia and Neuropil":"447246.3"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"983","Protein tissue specific Intensity":{"lung":"98273.7"},"Spatial region 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regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Group enriched","Protein cell type distribution":"Detected in some","Protein cell type specificity score":"1267","Protein cell type specific Intensity":{"Fallopian tube cells":"91858.5","Granulosa cells":"76954.2","Neurons":"211382.1"},"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in some","Protein tissue specificity score":null,"Protein tissue specific Intensity":{"ovary":"1743421.9"},"Spatial region specificity":"Broadly expressed","Antibody":["HPA030233"],"Reliability (IH)":"Approved","Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoplasm","Golgi 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specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in all","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Cancer enriched","RNA cancer distribution":"Detected in all","RNA cancer specificity score":"5","RNA cancer specific pTPM":{"Kidney Renal Clear Cell Carcinoma (TCGA)":"158.1"},"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in all","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in all","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":"Low region specificity","RNA macaque brain regional distribution":"Detected in all","RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":"Low region specificity","RNA mouse brain regional distribution":"Detected in all","RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":"Low region specificity","RNA pig brain regional distribution":"Detected in all","RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":"Low region specificity","RNA rat brain regional distribution":"Detected in all","RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Tissue enriched","Protein tissue distribution":"Detected in single","Protein tissue specificity score":"205","Protein tissue specific Intensity":{"intestine":"20489.9"},"Spatial region specificity":"Region enhanced","Antibody":["HPA049382","HPA076275"],"Reliability (IH)":"Uncertain","Reliability (Mouse Brain)":null,"Reliability (IF)":"Supported","Subcellular location":["Nucleoplasm","Cytosol"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 22: Eosinophils - Transcription","Tissue expression cluster":"Cluster 54: Non-specific - Ribosome","Brain expression cluster":"Cluster 39: Astrocytes - Mixed function","Cell line expression cluster":"Cluster 15: Kidney cancer - Membrane components","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":20,"Subcellular main location":["Nucleoplasm"],"Subcellular additional location":["Cytosol"],"Antibody RRID":{"HPA049382":null,"HPA076275":null},"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.03e-2"},"Cancer prognostics - Breast Invasive Carcinoma (TCGA)":{"prognostic type":"","prognostic":"unprognostic","is_prognostic":false,"p_val":"1.25e-1"},"Cancer prognostics - 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443","Uniprot":["Q9Y2A4"],"Chromosome":"19","Position":"12429706-12441021","Protein class":["Predicted intracellular proteins","Transcription factors"],"Biological process":["Transcription","Transcription regulation"],"Molecular function":["DNA-binding"],"Disease involvement":null,"Evidence":"Evidence at protein level","HPA evidence":"Evidence at protein level","UniProt evidence":"Evidence at transcript level","NeXtProt evidence":"Evidence at protein level","RNA tissue specificity":"Low tissue specificity","RNA tissue distribution":"Detected in many","RNA tissue specificity score":null,"RNA tissue specific nTPM":null,"RNA single cell type specificity":"Low cell type specificity","RNA single cell type distribution":"Detected in some","RNA single cell type specificity score":null,"RNA single cell type specific nCPM":null,"RNA single cell type group specificity":"Cell type enhanced","RNA single cell type group distribution":"Detected in some","RNA single cell type group specificity score":null,"RNA single cell type group specific nCPM":{"Ciliated cells":"3.2","Glial cells":"5.4","Megakaryocytes":"2.3","Neuronal cells":"3.0"},"RNA single nuclei brain specificity":"Low cell type specificity","RNA single nuclei brain distribution":"Detected in many","RNA single nuclei brain specificity score":null,"RNA single nuclei brain specific nCPM":null,"RNA single nuclei brain neurons specificity":"Low cell type specificity","RNA single nuclei brain neurons distribution":"Detected in many","RNA single nuclei brain neurons specificity score":null,"RNA single nuclei brain neurons specific nCPM":null,"RNA cancer specificity":"Low cancer specificity","RNA cancer distribution":"Detected in all","RNA cancer specificity score":null,"RNA cancer specific pTPM":null,"RNA brain regional specificity":"Low region specificity","RNA brain regional distribution":"Detected in all","RNA brain regional specificity score":null,"RNA brain regional specific nTPM":null,"RNA brain domain specificity":"Low domain specificity","RNA brain domain distribution":"Detected in all","RNA brain domain specificity score":null,"RNA brain domain specific nTPM":null,"RNA blood cell specificity":"Low immune cell specificity","RNA blood cell distribution":"Detected in many","RNA blood cell specificity score":null,"RNA blood cell specific nTPM":null,"RNA blood lineage specificity":"Low lineage specificity","RNA blood lineage distribution":"Detected in many","RNA blood lineage specificity score":null,"RNA blood lineage specific nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Not detected","Protein cell type distribution":"Not detected","Protein cell type specificity score":null,"Protein cell type specific Intensity":null,"Protein tissue specificity":"Not detected","Protein tissue distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Broadly expressed","Antibody":["HPA003150","HPA018683"],"Reliability (IH)":"Approved","Reliability (Mouse 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nTPM":null,"RNA cell line specificity":"Low cancer specificity","RNA cell line distribution":"Detected in many","RNA cell line specificity score":null,"RNA cell line specific nTPM":null,"RNA tissue cell type enrichment":null,"RNA macaque brain regional specificity":null,"RNA macaque brain regional distribution":null,"RNA macaque brain regional specificity score":null,"RNA macaque brain regional specific nTPM":null,"RNA mouse brain regional specificity":null,"RNA mouse brain regional distribution":null,"RNA mouse brain regional specificity score":null,"RNA mouse brain regional specific nTPM":null,"RNA pig brain regional specificity":null,"RNA pig brain regional distribution":null,"RNA pig brain regional specificity score":null,"RNA pig brain regional specific nTPM":null,"RNA rat brain regional specificity":null,"RNA rat brain regional distribution":null,"RNA rat brain regional specificity score":null,"RNA rat brain regional specific nTPM":null,"Protein cell type specificity":"Cell type 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distribution":"Not detected","Protein tissue specificity score":null,"Protein tissue specific Intensity":null,"Spatial region specificity":"Region enriched (niche group)","Antibody":["HPA062887"],"Reliability (IH)":null,"Reliability (Mouse Brain)":null,"Reliability (IF)":"Approved","Subcellular location":["Nucleoli"],"Secretome location":null,"Secretome function":null,"CCD Protein":"NA","CCD Transcript":"NA","Blood concentration - Conc. blood IM [pg\/L]":null,"Blood concentration - Conc. blood MS [pg\/L]":null,"Blood expression cluster":"Cluster 20: Non-specific - DNA binding","Tissue expression cluster":"Cluster 40: Non-specific - Mixed function","Brain expression cluster":"Cluster 11: White matter - Signal transduction","Cell line expression cluster":"Cluster 10: Ciliated cells - Ion channel activity","Single cell expression cluster":"Cluster 85: Non-specific - Mixed function","Interactions":3,"Subcellular main location":["Nucleoli"],"Subcellular additional location":null,"Antibody 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