Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" CEL "BSSL, MODY8" ENSG00000170835 "Carboxyl ester lipase" P19835 9 133061981-133071861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 545 "pancreas: 107112.3" "Group enriched" "Detected in some" 21 "Breast glandular cells: 371.9;Exocrine glandular cells: 517.2" "Cancer enriched" "Detected in many" 29 "pancreatic cancer: 469.3" "Region enriched" "Detected in all" 4 "choroid plexus: 24.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.1" "Pancreas - Exocrine glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008023, HPA052701" Enhanced "Secreted to digestive system" Enzyme NA NA 110000 "Cluster 15: Pancreas - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA008023: AB_1846509, HPA052701: AB_2681921" "prognostic unfavorable (4.14e-4)" "unprognostic (2.30e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-2)" "unprognostic (2.22e-1)" "unprognostic (2.48e-1)" "unprognostic (1.49e-1)" "unprognostic (6.27e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-2)" "unprognostic (2.51e-1)" "unprognostic (5.55e-2)" "unprognostic (2.26e-3)" "unprognostic (2.98e-1)" "unprognostic (4.41e-1)" "unprognostic (4.37e-2)" "unprognostic (1.02e-1)" LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 388.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 457.6;Kupffer cells: 634.6;Macrophages: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.7;intermediate monocyte: 355.8;myeloid DC: 123.8;non-classical monocyte: 199.7" "Group enriched" "Detected in all" 6 "dendritic cells: 123.8;monocytes: 355.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA 280000 "Cluster 40: Monocytes - Innate immune response" "Cluster 47: Spleen - Immune response" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" SOAT1 "ACAT, ACAT1, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 160.1" "Cell type enhanced" "Detected in many" "monocytes: 99.3;Prostatic glandular cells: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" 4 "Endoplasmic reticulum" "CAB009533: AB_633499, HPA047171: AB_2679967" "unprognostic (3.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.81e-3)" "unprognostic (7.81e-3)" "unprognostic (3.29e-1)" "unprognostic (9.00e-2)" "unprognostic (9.84e-2)" "unprognostic (1.06e-1)" "unprognostic (5.45e-3)" "unprognostic (7.02e-3)" "unprognostic (4.67e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-2)" "unprognostic (1.82e-1)" SOAT2 ACAT2 ENSG00000167780 "Sterol O-acyltransferase 2" O75908 12 53103486-53124535 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 18.9" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 16.9" "Group enriched" "Detected in some" 8 "liver cancer: 5.2;testis cancer: 5.5" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.1" "Lineage enriched" "Detected in single" 6 "T-cells: 1.1" "Cancer enhanced" "Detected in some" "liver cancer: 5.5" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 1 "unprognostic (2.53e-1)" "unprognostic (2.72e-3)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (1.30e-4)" "unprognostic (3.88e-3)" "unprognostic (9.26e-2)" "unprognostic (4.20e-2)" "unprognostic (1.32e-1)" "unprognostic (3.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.53e-1)" "unprognostic (1.83e-2)" "unprognostic (9.05e-2)" "unprognostic (2.37e-1)" "unprognostic (7.58e-3)" "unprognostic (3.28e-1)"