Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" AANAT SNAT ENSG00000129673 "Aralkylamine N-acetyltransferase" Q16613 17 76453351-76470117 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Melatonin biosynthesis" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 10.6;testis: 4.5" "Cell type enriched" "Detected in some" 12 "Bipolar cells: 227.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054321 Supported Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" 3 Cytosol "HPA054321: AB_2682449" "unprognostic (7.89e-2)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-1)" "unprognostic (1.83e-2)" "unprognostic (2.03e-2)" "unprognostic (1.05e-2)" "unprognostic (3.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.61e-1)" "unprognostic (9.30e-2)" "unprognostic (4.19e-1)" "unprognostic (2.81e-7)" "unprognostic (1.04e-1)" "unprognostic (6.00e-2)" "unprognostic (4.47e-2)" "unprognostic (1.34e-2)" ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276369-99291003 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 305 "liver: 2653.7" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 208.0" "Cancer enriched" "Detected in some" 251 "liver cancer: 165.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatocytes" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Plasma membrane,Cytosol" NA NA 38000000 "Cluster 31: Liver - Plasma proteins" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 43: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "CAB009562: AB_2257984, HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.89e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.78e-3)" "unprognostic (4.25e-1)" "unprognostic (4.79e-3)" "unprognostic (6.21e-2)" "unprognostic (9.36e-2)" "unprognostic (3.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-2)" ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1449.1;liver: 5678.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 761.6;Hepatocytes: 4180.2;Mesothelial cells: 1146.2" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Region enhanced" "Detected in many" "choroid plexus: 24.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Testis - Endothelial cells" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 83: Liver - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 43: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 581.0;liver: 1997.6;stomach 1: 555.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 230.3;Enteroendocrine cells: 216.1;Exocrine glandular cells: 344.5;Gastric mucus-secreting cells: 669.1;Hepatocytes: 514.4;Undifferentiated cells: 339.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 53.7" "Liver - Hepatocytes, Stomach - Gastric mucous cells" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" NA NA 31000000 "Cluster 83: Liver - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.55e-4)" "prognostic favorable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" ADH4 ADH-2 ENSG00000198099 "Alcohol dehydrogenase 4 (class II), pi polypeptide" P08319 4 99123657-99157792 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "liver: 4994.3" "Cell type enriched" "Detected in some" 32 "Hepatocytes: 1104.3" "Cancer enriched" "Detected in some" 60 "liver cancer: 230.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.8" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA020525 Enhanced Uncertain Nucleoplasm,Cytosol NA NA 20000000 "Cluster 31: Liver - Plasma proteins" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" "HPA020525: AB_1844609" "unprognostic (2.75e-1)" "unprognostic (1.69e-2)" "unprognostic (1.85e-2)" "unprognostic (5.54e-3)" "unprognostic (2.14e-2)" "unprognostic (1.33e-2)" "prognostic favorable (7.08e-6)" "unprognostic (1.49e-1)" "unprognostic (1.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.88e-1)" "unprognostic (2.34e-2)" "unprognostic (7.16e-3)" "unprognostic (2.20e-1)" "unprognostic (5.89e-3)" ADH5 "ADH-3, ADHX, FDH, GSNOR" ENSG00000197894 "Alcohol dehydrogenase 5 (class III), chi polypeptide" P11766 4 99070978-99088801 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA044578, HPA061919" Approved NA NA 5300000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 32: Smooth muscle cells - Muscle contraction" "HPA044578: AB_2679002, HPA061919: AB_2684638" "unprognostic (1.05e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-3)" "prognostic favorable (9.90e-5)" "unprognostic (2.63e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (9.48e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (1.22e-1)" "prognostic favorable (4.58e-10)" "unprognostic (1.79e-3)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" ADH6 ADH-5 ENSG00000172955 "Alcohol dehydrogenase 6 (class V)" P28332 4 99202638-99219537 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 682.3" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 321.3" "Cancer enriched" "Detected in many" 18 "liver cancer: 46.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 6.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells" "Not detected" "Not detected" "HPA067946, HPA069081" Enhanced NA NA 3400000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" 1 "HPA067946: AB_2732776, HPA069081: AB_2732127" "unprognostic (1.38e-2)" "unprognostic (1.83e-2)" "unprognostic (5.82e-2)" "unprognostic (1.49e-3)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (5.11e-3)" "unprognostic (2.40e-1)" "unprognostic (3.60e-2)" "unprognostic (1.35e-1)" "unprognostic (9.72e-3)" "unprognostic (1.67e-1)" "unprognostic (3.66e-3)" "unprognostic (1.35e-1)" "unprognostic (2.43e-1)" "unprognostic (8.74e-3)" "unprognostic (3.86e-3)" ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435510 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 194.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 113.2;Basal respiratory cells: 76.9;Basal squamous epithelial cells: 58.3;Club cells: 53.1;Squamous epithelial cells: 235.2;Suprabasal keratinocytes: 202.2" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Esophageal cancer: 32.8;Gallbladder cancer: 101.9" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" ADHFE1 FLJ32430 ENSG00000147576 "Alcohol dehydrogenase iron containing 1" Q8IWW8 8 66432492-66468907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 30.4;skeletal muscle: 28.2;tongue: 30.1" "Cell type enhanced" "Detected in many" "Astrocytes: 72.5;Cardiomyocytes: 41.9;Syncytiotrophoblasts: 182.3" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023062 Enhanced NA NA "Cluster 23: Non-specific - Cellular respiration" "Cluster 39: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "HPA023062: AB_1844611" "prognostic favorable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favorable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 167.4;smooth muscle: 123.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 66.8;Extravillous trophoblasts: 50.9;Hepatocytes: 114.7;Pancreatic endocrine cells: 54.3;Proximal tubular cells: 169.8;Undifferentiated cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021037, HPA077080" Enhanced Supported Mitochondria NA NA 500000 "Cluster 33: Non-specific - ATP binding" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 56: Proximal tubular cells - Amino acid metabolism" Mitochondria "HPA021037: AB_1844724, HPA077080: " "unprognostic (4.16e-1)" "unprognostic (1.98e-2)" "unprognostic (5.84e-2)" "unprognostic (1.55e-3)" "unprognostic (2.47e-2)" "unprognostic (4.48e-3)" "unprognostic (2.84e-3)" "unprognostic (2.70e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (1.00e-1)" "prognostic favorable (2.05e-4)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.89e-2)" ALDH2 ENSG00000111275 "Aldehyde dehydrogenase 2 family member" P05091 12 111766887-111817532 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Dwarfism, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 831.4" "Cell type enhanced" "Detected in all" "Hepatocytes: 982.7;Proximal tubular cells: 647.5" "Cancer enhanced" "Detected in all" "liver cancer: 71.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 212.7;myeloid DC: 213.7" "Group enriched" "Detected in many" 4 "dendritic cells: 213.7;monocytes: 212.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051065 Approved NA NA 2200000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 83: Liver - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 58: Macrophages - Innate immune response" 1 "HPA051065: AB_2681332" "unprognostic (9.22e-3)" "unprognostic (1.20e-2)" "unprognostic (4.14e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "prognostic favorable (3.95e-7)" "unprognostic (5.62e-3)" "unprognostic (3.00e-1)" "unprognostic (1.16e-1)" "unprognostic (8.22e-2)" "unprognostic (1.51e-1)" "prognostic favorable (5.24e-6)" "unprognostic (9.70e-2)" "unprognostic (3.40e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (7.71e-4)" ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 279.3" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 246.3;Basal squamous epithelial cells: 281.7;Squamous epithelial cells: 221.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Skin - Keratinocyte (other), Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 32000 "Cluster 33: Non-specific - ATP binding" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: AB_1844728" "unprognostic (1.42e-1)" "unprognostic (7.62e-2)" "unprognostic (7.77e-2)" "unprognostic (2.49e-2)" "unprognostic (4.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-2)" "unprognostic (2.23e-1)" "unprognostic (3.93e-3)" "unprognostic (2.40e-1)" "unprognostic (2.63e-1)" "prognostic favorable (3.85e-8)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-2)" "unprognostic (1.26e-1)" ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 157.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 455.7;Proximal tubular cells: 274.6;Syncytiotrophoblasts: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.3" "Cancer enhanced" "Detected in all" "Rhabdoid: 301.3" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skin - Mitotic cells (Skin), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 430000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" 1 Mitochondria Cytosol "HPA023296: AB_1844738, HPA053675: " "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (2.07e-2)" "unprognostic (2.20e-2)" "unprognostic (4.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.58e-3)" "unprognostic (9.49e-3)" "unprognostic (7.61e-2)" "unprognostic (7.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.33e-1)" "prognostic favorable (3.08e-4)" "unprognostic (1.51e-1)" "unprognostic (3.70e-1)" "unprognostic (3.10e-3)" "unprognostic (4.93e-2)" ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698562 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 282.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA 2000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Breast glandular cells - Lactation" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" AOX1 "AO, AOH1" ENSG00000138356 "Aldehyde oxidase 1" Q06278 2 200586014-200677064 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 291.3;liver: 864.2" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 701.6" "Cancer enriched" "Detected in many" 9 "liver cancer: 122.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA040199, HPA040215" Enhanced NA NA 3300000 "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 62: Hepatocytes - Metabolism" "HPA040199: AB_10795273, HPA040215: AB_10795360" "unprognostic (4.39e-2)" "unprognostic (1.03e-3)" "unprognostic (1.96e-1)" "unprognostic (3.15e-2)" "unprognostic (1.17e-4)" "unprognostic (1.92e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (5.48e-2)" "unprognostic (2.00e-2)" "prognostic favorable (6.05e-5)" "unprognostic (1.33e-2)" "unprognostic (8.16e-3)" "unprognostic (3.38e-2)" "unprognostic (4.99e-3)" ASMT "ASMTY, HIOMT, HIOMTY" ENSG00000196433 "Acetylserotonin O-methyltransferase" P46597 X 1615059-1643081 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Melatonin biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "choroid plexus: 7.4" "Cell type enhanced" "Detected in some" "Early spermatids: 1.2;Excitatory neurons: 1.4;Extravillous trophoblasts: 1.2;Inhibitory neurons: 1.3;Late spermatids: 1.2;Oligodendrocytes: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.1" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "Brain cancer: 2.3;lymphoma: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 61: Plasma cells - Immunoglobulins & histones" "unprognostic (1.84e-2)" "unprognostic (1.63e-3)" "unprognostic (1.89e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-1)" "unprognostic (8.55e-4)" "unprognostic (1.54e-1)" "unprognostic (2.27e-2)" "unprognostic (4.30e-3)" "unprognostic (1.56e-1)" "unprognostic (1.43e-3)" "unprognostic (2.64e-1)" "unprognostic (4.04e-3)" "unprognostic (1.49e-1)" "unprognostic (3.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.79e-3)" CHST10 HNK-1ST ENSG00000115526 "Carbohydrate sulfotransferase 10" O43529 2 100391860-100417668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 20.4;Horizontal cells: 14.5;Muller glia cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012884, HPA051545" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA 680000 "Cluster 24: Non-specific - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" Cytosol "HPA012884: AB_1846710, HPA051545: AB_2681529" "unprognostic (5.40e-3)" "unprognostic (3.62e-2)" "unprognostic (3.44e-2)" "unprognostic (2.03e-1)" "unprognostic (3.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.89e-2)" "unprognostic (1.44e-1)" "unprognostic (1.78e-1)" "unprognostic (4.54e-2)" "prognostic favorable (4.05e-4)" "unprognostic (8.02e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-2)" "unprognostic (3.73e-2)" "unprognostic (3.06e-2)" "unprognostic (3.27e-1)" CHST2 C6ST ENSG00000175040 "Carbohydrate sulfotransferase 2" Q9Y4C5 3 143119771-143124014 "Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.3" "Cell type enhanced" "Detected in many" "monocytes: 109.1;Muller glia cells: 92.5;NK-cells: 145.7;Plasma cells: 78.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.3;NK-cell: 4.9;non-classical monocyte: 11.4" "Group enriched" "Detected in many" 5 "monocytes: 11.4;NK-cells: 4.9" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013620 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 61: Plasma cells - Immunoglobulins & histones" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA013620: AB_2668861" "unprognostic (1.55e-2)" "unprognostic (2.20e-1)" "unprognostic (7.64e-3)" "unprognostic (2.75e-1)" "unprognostic (8.97e-3)" "unprognostic (2.83e-1)" "unprognostic (2.70e-2)" "unprognostic (2.06e-1)" "unprognostic (2.76e-1)" "unprognostic (4.11e-2)" "unprognostic (8.96e-3)" "unprognostic (9.15e-2)" "unprognostic (1.31e-2)" "unprognostic (7.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.58e-3)" "unprognostic (1.34e-1)" CHST4 "HEC-GLCNAC-6-ST, LSST" ENSG00000140835 "Carbohydrate sulfotransferase 4" Q8NCG5 16 71525233-71538748 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "gallbladder: 67.1" "Cell type enriched" "Detected in some" 27 "Cholangiocytes: 173.6" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 10.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 13.1;pancreatic cancer: 6.4" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA021955 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "HPA021955: AB_1846723" "unprognostic (2.22e-3)" "unprognostic (1.41e-1)" "unprognostic (8.87e-2)" "unprognostic (3.35e-2)" "unprognostic (4.76e-3)" "unprognostic (6.86e-2)" "prognostic unfavorable (9.24e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-6)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" CHST5 "FLJ22167, I-GLCNAC-6-ST" ENSG00000135702 "Carbohydrate sulfotransferase 5" Q9GZS9 16 75528530-75536108 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "intestine: 84.9" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4.8;Enteroendocrine cells: 6.2;Excitatory neurons: 2.1;Intestinal goblet cells: 6.1;Paneth cells: 3.2;Proximal enterocytes: 9.8" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.4;stomach cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.4" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells" "HPA043804, HPA068029" Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "HPA043804: AB_10960563, HPA068029: " "unprognostic (6.82e-3)" "unprognostic (2.02e-1)" "unprognostic (1.99e-3)" "unprognostic (1.03e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-2)" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (2.09e-2)" "unprognostic (9.03e-3)" "unprognostic (4.27e-2)" "unprognostic (2.05e-3)" "unprognostic (3.56e-1)" "unprognostic (2.52e-2)" "unprognostic (1.46e-1)" "unprognostic (1.42e-2)" CHST6 MCDC1 ENSG00000183196 "Carbohydrate sulfotransferase 6" Q9GZX3 16 75472052-75495445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.2;brain: 9.1;cervix: 9.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 14.2;Ciliated cells: 65.1;Club cells: 12.5;Ionocytes: 39.0;Oligodendrocytes: 15.8;Serous glandular cells: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 6.8" "Lung - Respiratory ciliated cells" HPA068029 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 42: Ciliated cells - Cilium assembly" "HPA068029: " "unprognostic (2.28e-2)" "unprognostic (2.25e-2)" "unprognostic (1.07e-1)" "unprognostic (3.93e-3)" "unprognostic (3.30e-2)" "unprognostic (4.02e-2)" "unprognostic (7.15e-2)" "unprognostic (1.73e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (3.16e-2)" "unprognostic (1.07e-1)" "unprognostic (1.10e-7)" "unprognostic (1.23e-1)" "unprognostic (1.14e-1)" "unprognostic (5.78e-2)" "unprognostic (2.80e-4)" CHST7 "C6ST-2, C6ST2" ENSG00000147119 "Carbohydrate sulfotransferase 7" Q9NS84 X 46573765-46598496 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 34.1" "Cell type enhanced" "Detected in many" "Langerhans cells: 55.1;monocytes: 97.1;Ovarian stromal cells: 46.2;Peritubular cells: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.6" "Group enriched" "Detected in many" 10 "granulocytes: 10.9;monocytes: 10.3;T-cells: 18.6" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003919, HPA030503" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 9800 "Cluster 33: Non-specific - ATP binding" "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" "Nucleoplasm, Vesicles" "HPA003919: AB_10601258, HPA030503: " "unprognostic (3.16e-1)" "prognostic favorable (7.20e-4)" "unprognostic (1.11e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" "unprognostic (7.85e-2)" "unprognostic (9.82e-3)" "unprognostic (3.52e-2)" "unprognostic (2.61e-1)" "unprognostic (2.81e-1)" "unprognostic (2.39e-3)" "unprognostic (6.71e-2)" "unprognostic (1.19e-1)" "unprognostic (8.85e-3)" "unprognostic (8.28e-2)" "unprognostic (1.50e-1)" "unprognostic (4.39e-2)" CHST8 GALNAC4ST-1 ENSG00000124302 "Carbohydrate sulfotransferase 8" Q9H2A9 19 33621953-33773509 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "brain: 17.7;pituitary gland: 62.2" "Cell type enhanced" "Detected in some" "Early spermatids: 9.3;Excitatory neurons: 11.4;Granulosa cells: 10.8;Horizontal cells: 13.2;Late spermatids: 54.1;Oligodendrocyte precursor cells: 11.3;Pancreatic endocrine cells: 13.6" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;glioma: 4.9;testis cancer: 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 12.0" "Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA016004 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 36: Late spermatids - Unknown function" 2 "HPA016004: AB_1846731" "unprognostic (1.00e-1)" "unprognostic (6.58e-2)" "unprognostic (1.21e-1)" "unprognostic (1.45e-2)" "unprognostic (9.44e-2)" "unprognostic (2.96e-2)" "unprognostic (1.15e-2)" "unprognostic (5.75e-2)" "unprognostic (8.41e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-2)" "unprognostic (1.54e-1)" "unprognostic (6.98e-8)" "unprognostic (9.37e-3)" "unprognostic (2.61e-1)" "unprognostic (3.28e-1)" "unprognostic (3.87e-2)" CHST9 "GALNAC-4-ST2, GALNAC4ST-2" ENSG00000154080 "Carbohydrate sulfotransferase 9" Q7L1S5 18 26906481-27185308 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 13.4" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 60.2;Ciliated cells: 140.9;Club cells: 130.0;Ionocytes: 89.1;Muller glia cells: 57.7;Oligodendrocyte precursor cells: 157.1;Salivary duct cells: 111.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 5.9;liver cancer: 10.6" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA011393 Uncertain "Intracellular and membrane" Enzyme NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA011393: AB_1846733" "unprognostic (9.24e-3)" "unprognostic (1.13e-2)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (4.53e-3)" "unprognostic (9.98e-3)" "unprognostic (9.21e-3)" "unprognostic (7.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.04e-2)" "unprognostic (3.54e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (3.93e-3)" COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941371-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 896.4;Syncytiotrophoblasts: 630.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" NA NA 43000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 39: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 24: Cytotrophoblasts - Mitochondria" 53 Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: AB_1078402" "unprognostic (5.20e-2)" "unprognostic (2.73e-2)" "unprognostic (3.08e-2)" "prognostic favorable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (2.32e-3)" "unprognostic (5.54e-3)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-3)" "prognostic favorable (5.67e-4)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.07e-2)" CYP1A1 "CP11, CYP1, P1-450, P450-C, P450DX" ENSG00000140465 "Cytochrome P450 family 1 subfamily A member 1" P04798 15 74719542-74725536 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 64.1;urinary bladder: 61.4" "Cell type enhanced" "Detected in some" "Adipocytes: 15.2;Ductal cells: 2.5;Endothelial cells: 2.7;Glandular and luminal cells: 5.5;Hepatocytes: 9.8" "Group enriched" "Detected in some" 24 "liver cancer: 18.6;urothelial cancer: 54.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 53.3;Esophageal cancer: 95.1" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB018654 Uncertain NA NA "Cluster 83: Liver - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "CAB018654: AB_2088699" "unprognostic (1.71e-2)" "unprognostic (7.86e-2)" "unprognostic (2.57e-2)" "unprognostic (2.89e-1)" "unprognostic (5.45e-3)" "unprognostic (6.34e-2)" "unprognostic (3.08e-1)" "unprognostic (6.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (4.21e-2)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-1)" "unprognostic (1.28e-1)" CYP1A2 "CP12, P3-450" ENSG00000140505 "Cytochrome P450 family 1 subfamily A member 2" P05177 15 74748845-74756607 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 358 "liver: 495.9" "Cell type enriched" "Detected in some" 56 "Hepatocytes: 535.0" "Group enriched" "Detected in some" 22 "liver cancer: 25.3;urothelial cancer: 6.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.1" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.1" "Low cancer specificity" "Detected in single" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" CAB016531 Enhanced NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 31: Liver - Plasma proteins" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 43: Hepatocytes - Metabolism" 1 "CAB016531: AB_629359" "unprognostic (1.54e-4)" "unprognostic (1.29e-1)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "unprognostic (1.59e-2)" "unprognostic (1.76e-1)" "unprognostic (1.17e-2)" "unprognostic (5.48e-2)" "unprognostic (2.33e-2)" "unprognostic (7.41e-2)" "unprognostic (2.53e-1)" CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 100.6;Fibroblasts: 139.3;Leydig cells: 155.9;Macrophages: 120.3;Peritubular cells: 168.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 157.2" "Lineage enriched" "Detected in many" 24 "monocytes: 157.2" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "midbrain: 16.4;spinal cord: 51.7" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" DDC AADC ENSG00000132437 "Dopa decarboxylase" P20711 7 50458436-50565405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 161.2;kidney: 303.6;retina: 170.3" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 368.3;Proximal enterocytes: 394.0;Proximal tubular cells: 315.4;Rod photoreceptor cells: 478.2" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.5;liver cancer: 13.4;pancreatic cancer: 6.4;renal cancer: 18.7;stomach cancer: 9.9" "Group enriched" "Detected in many" 9 "midbrain: 179.5;pons: 59.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 108.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "midbrain: 97.7;pons: 40.1" HPA017742 Enhanced Approved "Actin filaments" NA NA 120000 "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" 1 "Actin filaments" "HPA017742: AB_1847832" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (2.57e-2)" "unprognostic (3.49e-5)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.15e-2)" "unprognostic (4.69e-2)" "unprognostic (5.44e-2)" "unprognostic (9.36e-3)" "unprognostic (5.24e-2)" "unprognostic (1.76e-3)" "unprognostic (1.60e-1)" "unprognostic (3.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.16e-1)" GAL3ST2 GP3ST ENSG00000154252 "Galactose-3-O-sulfotransferase 2" Q9H3Q3 2 241776822-241804287 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "intestine: 9.1" "Cell type enhanced" "Detected in single" "Mesothelial cells: 1.2" "Group enriched" "Detected in many" 6 "colorectal cancer: 6.7;ovarian cancer: 4.9;stomach cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "colorectal cancer: 7.5" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA071809 Enhanced "Intracellular and membrane" Enzyme NA NA "Cluster 45: Intestine - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 7: T-cells - T-cell receptor" 1 "HPA071809: AB_2686450" "unprognostic (5.22e-3)" "unprognostic (6.52e-2)" "unprognostic (1.85e-2)" "unprognostic (4.04e-3)" "unprognostic (3.04e-4)" "unprognostic (3.45e-2)" "unprognostic (2.48e-2)" "unprognostic (2.87e-1)" "unprognostic (4.13e-2)" "unprognostic (2.25e-3)" "unprognostic (2.58e-1)" "unprognostic (4.99e-2)" "unprognostic (2.87e-11)" "unprognostic (4.32e-2)" "unprognostic (1.55e-1)" "unprognostic (5.99e-3)" "unprognostic (3.49e-1)" GAL3ST3 GAL3ST2 ENSG00000175229 "Galactose-3-O-sulfotransferase 3" Q96A11 11 66040765-66049161 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.0;thyroid gland: 16.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.6;Cardiomyocytes: 3.8;Cone photoreceptor cells: 8.5;Excitatory neurons: 3.5;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 7.1;Rod photoreceptor cells: 21.5" "Group enriched" "Detected in many" 5 "glioma: 4.7;ovarian cancer: 5.5;thyroid cancer: 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.5" "Heart muscle - Cardiomyocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Enzyme NA NA "Cluster 64: Neuronal - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" "prognostic unfavorable (6.53e-6)" "unprognostic (1.24e-1)" "unprognostic (3.30e-1)" "unprognostic (1.57e-2)" "unprognostic (2.62e-1)" "unprognostic (6.08e-2)" "unprognostic (2.01e-3)" "unprognostic (7.26e-2)" "unprognostic (2.07e-2)" "unprognostic (1.40e-1)" "unprognostic (5.29e-1)" GAL3ST4 FLJ12116 ENSG00000197093 "Galactose-3-O-sulfotransferase 4" Q96RP7 7 100159244-100168617 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 33.8;Melanocytes: 13.7;Microglial cells: 22.4;Oligodendrocyte precursor cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 4.5;naive CD4 T-cell: 15.0;naive CD8 T-cell: 4.6;plasmacytoid DC: 4.7" "Group enriched" "Detected in many" 29 "dendritic cells: 4.7;T-cells: 15.0" "Cancer enhanced" "Detected in many" "skin cancer: 9.5" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038137, HPA038138" Uncertain Approved Nucleoplasm,Cytosol NA NA 35000 "Cluster 30: Non-specific - DNA binding" "Cluster 13: Skin - Cornification" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 58: Macrophages - Innate immune response" Nucleoplasm Cytosol "HPA038137: AB_10697239, HPA038138: AB_2675854" "unprognostic (4.22e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.44e-4)" "unprognostic (8.64e-2)" "unprognostic (3.01e-2)" "unprognostic (1.40e-1)" "unprognostic (3.10e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.57e-4)" "unprognostic (2.80e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (4.14e-4)" "unprognostic (3.98e-2)" "unprognostic (9.67e-2)" "unprognostic (1.89e-2)" "unprognostic (5.36e-2)" HS2ST1 KIAA0448 ENSG00000153936 "Heparan sulfate 2-O-sulfotransferase 1" Q7LGA3 1 86914635-87109982 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 152.7;Excitatory neurons: 121.8;Inhibitory neurons: 124.6;Oligodendrocyte precursor cells: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043069, HPA043603, HPA075001" Supported Approved Mitochondria "Intracellular and membrane" Enzyme No No "Cluster 34: B-cells - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 47: Astrocytes - Unknown function" Mitochondria "HPA043069: AB_10964127, HPA043603: AB_10963432, HPA075001: AB_2686726" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (1.28e-3)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (7.20e-2)" "unprognostic (5.34e-2)" "unprognostic (7.70e-2)" "unprognostic (1.70e-3)" "unprognostic (1.45e-1)" "unprognostic (5.80e-2)" "unprognostic (1.63e-2)" "unprognostic (5.07e-2)" "unprognostic (3.24e-1)" "unprognostic (7.58e-2)" HS6ST1 HS6ST ENSG00000136720 "Heparan sulfate 6-O-sulfotransferase 1" O60243 2 128236716-128318868 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 73.1;granulocytes: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044586 Approved Nucleoplasm "Intracellular and membrane" Enzyme NA NA 72000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 30: Granulocytes - Unknown function" 2 Nucleoplasm "HPA044586: AB_10963057" "unprognostic (9.94e-2)" "unprognostic (8.93e-3)" "unprognostic (4.94e-3)" "unprognostic (6.69e-3)" "unprognostic (1.99e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-2)" "unprognostic (3.21e-2)" "unprognostic (2.87e-1)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (4.28e-2)" "unprognostic (1.21e-2)" "unprognostic (2.77e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.66e-2)" HS6ST2 HS6ST-2 ENSG00000171004 "Heparan sulfate 6-O-sulfotransferase 2" Q96MM7 X 132626015-132961395 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.4;kidney: 15.3;ovary: 15.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.8;Excitatory neurons: 36.3;Inhibitory neurons: 42.4;Leydig cells: 60.8;Oligodendrocyte precursor cells: 50.9;Peritubular cells: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Ascending Loop of Henle cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034625 Uncertain Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus" "Plasma membrane" "HPA034625: AB_10612119" "unprognostic (7.62e-3)" "unprognostic (4.89e-2)" "unprognostic (2.89e-1)" "unprognostic (1.41e-1)" "unprognostic (3.24e-1)" "unprognostic (5.54e-2)" "unprognostic (1.44e-1)" "unprognostic (1.71e-2)" "unprognostic (1.14e-2)" "unprognostic (2.13e-1)" "unprognostic (1.06e-1)" "unprognostic (3.57e-1)" "unprognostic (8.39e-5)" "unprognostic (1.36e-3)" "unprognostic (1.44e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.03e-4)" HS6ST3 ENSG00000185352 "Heparan sulfate 6-O-sulfotransferase 3" Q8IZP7 13 96090107-96839562 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 16.7" "Group enriched" "Detected in some" 27 "Excitatory neurons: 1266.4;Inhibitory neurons: 859.7;Oligodendrocyte precursor cells: 908.9" "Cancer enhanced" "Detected in many" "breast cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.2;Neuroblastoma: 3.3" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA078257 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments" "Intracellular and membrane" Enzyme NA NA 24000 "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Nuclear membrane" "Plasma membrane, Actin filaments" "HPA078257: AB_2732374" "unprognostic (2.34e-2)" "unprognostic (1.90e-2)" "unprognostic (2.82e-2)" "unprognostic (1.72e-2)" "unprognostic (4.88e-2)" "unprognostic (2.78e-2)" "unprognostic (1.55e-1)" "unprognostic (3.67e-3)" "unprognostic (8.11e-3)" "unprognostic (1.19e-1)" "prognostic favorable (6.12e-5)" "unprognostic (1.54e-4)" "unprognostic (2.24e-1)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" IDO1 "IDO, INDO" ENSG00000131203 "Indoleamine 2,3-dioxygenase 1" P14902 8 39902275-39928790 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 57.3;placenta: 107.2" "Group enriched" "Detected in many" 5 "Glandular and luminal cells: 295.2;Schwann cells: 323.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 14 "eosinophil: 465.9" "Lineage enriched" "Detected in many" 18 "granulocytes: 465.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 15.4" "Adipose subcutaneous - T-cells, Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in many" 12 "basal ganglia: 34.1" "Low region specificity" "Detected in all" "HPA023072, HPA023149, HPA027772, CAB072820" Enhanced Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 58: Placenta - Pregnancy" "Cluster 23: Choroid plexus - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" "Nucleoplasm, Cytosol" "Vesicles, Mitochondria" "CAB072820: , HPA023072: AB_1846220, HPA023149: AB_1846221, HPA027772: AB_1846222" "unprognostic (1.68e-2)" "unprognostic (1.71e-2)" "unprognostic (4.08e-3)" "unprognostic (7.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.09e-2)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "prognostic favorable (5.27e-4)" "prognostic favorable (3.32e-4)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (1.12e-7)" "unprognostic (4.18e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.97e-2)" IDO2 INDOL1 ENSG00000188676 "Indoleamine 2,3-dioxygenase 2" Q6ZQW0 8 39934614-40016392 "Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "liver: 3.2;placenta: 5.3" "Cell type enhanced" "Detected in some" "Early spermatids: 19.8;Glandular and luminal cells: 45.7;Late spermatids: 11.4;Schwann cells: 9.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054911 Approved Cytosol NA NA "Cluster 11: Liver - Plasma proteins" "Cluster 5: Rhabdoid - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" Cytosol "HPA054911: " "unprognostic (2.00e-3)" "unprognostic (2.34e-5)" "unprognostic (2.22e-3)" "unprognostic (4.41e-3)" "unprognostic (5.37e-2)" "unprognostic (3.69e-5)" "unprognostic (1.19e-1)" "unprognostic (4.73e-3)" "unprognostic (1.20e-2)" "unprognostic (2.78e-1)" "unprognostic (4.11e-3)" "unprognostic (2.25e-1)" "unprognostic (6.47e-7)" "unprognostic (3.25e-2)" "unprognostic (1.96e-3)" "unprognostic (3.35e-2)" "unprognostic (3.08e-3)" INMT ENSG00000241644 "Indolethylamine N-methyltransferase" O95050 7 30697985-30757602 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Detoxification "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 199.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 88.0;Leydig cells: 277.1;Mesothelial cells: 163.1;Peritubular cells: 439.3;Smooth muscle cells: 89.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 22.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Adipose visceral - Mesothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "spinal cord: 35.6" HPA061343 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "Golgi apparatus, Vesicles" "HPA061343: AB_2684483" "unprognostic (1.70e-1)" "unprognostic (4.36e-2)" "unprognostic (5.26e-2)" "unprognostic (6.78e-3)" "unprognostic (1.59e-1)" "unprognostic (3.39e-4)" "prognostic favorable (5.72e-4)" "unprognostic (3.08e-2)" "unprognostic (3.94e-2)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (9.07e-2)" "unprognostic (4.97e-2)" "unprognostic (1.62e-2)" "unprognostic (1.43e-2)" "unprognostic (9.71e-2)" "unprognostic (1.58e-2)" LRRC51 ENSG00000184154 "Leucine rich repeat containing 51" Q96E66 11 72080337-72096895 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 65.2;testis: 109.4" "Cell type enriched" "Detected in many" 5 "Late spermatids: 2162.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039949 Approved Uncertain Microtubules NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" Microtubules "HPA039949: AB_10960708" "unprognostic (2.68e-1)" "unprognostic (6.43e-2)" "unprognostic (1.85e-2)" "prognostic favorable (7.70e-4)" "unprognostic (8.09e-2)" "unprognostic (9.07e-2)" "unprognostic (1.42e-1)" "unprognostic (1.90e-1)" "unprognostic (4.22e-2)" "prognostic favorable (5.36e-4)" "unprognostic (6.12e-2)" "unprognostic (8.43e-2)" "unprognostic (2.64e-2)" "unprognostic (1.58e-1)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (1.44e-1)" MAOA ENSG00000189221 "Monoamine oxidase A" P21397 X 43654907-43746817 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" Oxidoreductase "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 213.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 309.6;Proximal enterocytes: 817.1;Proximal tubular cells: 517.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 47.6;prostate cancer: 69.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009437, HPA054807, HPA059299" Enhanced Supported Mitochondria,Cytosol No No "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 50: Lymphoma - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 1 Mitochondria Cytosol "CAB009437: AB_2137260, HPA054807: AB_2682607, HPA059299: AB_2683970" "unprognostic (9.54e-3)" "unprognostic (1.63e-1)" "unprognostic (7.99e-2)" "unprognostic (3.07e-1)" "unprognostic (6.75e-2)" "unprognostic (3.32e-1)" "unprognostic (9.51e-2)" "unprognostic (6.89e-3)" "unprognostic (2.21e-1)" "unprognostic (4.29e-2)" "unprognostic (3.94e-1)" "unprognostic (3.54e-1)" "unprognostic (1.45e-3)" "unprognostic (1.16e-2)" "unprognostic (1.47e-1)" "unprognostic (4.04e-2)" "unprognostic (2.98e-3)" MAOB ENSG00000069535 "Monoamine oxidase B" P27338 X 43766610-43882450 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 308.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 130.1;granulocytes: 213.3;Hepatocytes: 210.6;Ovarian stromal cells: 154.7;Proximal enterocytes: 179.7;Proximal tubular cells: 142.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 36.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Fibroblast_1, Prostate - Smooth muscle cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002328, CAB037200" Enhanced NA NA 110000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 6: Ovarian stromal cells - Transcription" 14 "CAB037200: AB_1841012, HPA002328: AB_1854062" "unprognostic (1.19e-2)" "unprognostic (1.36e-1)" "unprognostic (5.16e-2)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.69e-2)" "unprognostic (5.61e-2)" "unprognostic (4.37e-2)" "unprognostic (1.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (9.74e-2)" "unprognostic (5.35e-3)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (1.90e-3)" NDST1 "HSST, NST1" ENSG00000070614 "N-deacetylase and N-sulfotransferase 1" P52848 5 150485818-150558211 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Multifunctional enzyme, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 1.4;classical monocyte: 5.5;eosinophil: 3.6;intermediate monocyte: 1.7;myeloid DC: 4.2;neutrophil: 5.4;non-classical monocyte: 4.7" "Group enriched" "Detected in many" 10 "dendritic cells: 4.2;granulocytes: 5.4;monocytes: 5.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060532 Approved NA NA 1400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 27: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 17: Breast glandular cells - Lactation" "HPA060532: AB_2684310" "unprognostic (1.36e-1)" "unprognostic (5.54e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (6.99e-4)" "unprognostic (1.77e-1)" "unprognostic (3.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.47e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.97e-3)" "unprognostic (6.92e-2)" "unprognostic (7.45e-2)" "unprognostic (2.46e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (6.08e-2)" NDST2 "HSST2, NST2" ENSG00000166507 "N-deacetylase and N-sulfotransferase 2" P52849 10 73801911-73811798 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 13.0;granulocytes: 22.6;monocytes: 18.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051515 Approved Approved Cytosol NA NA 130000 "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" Cytosol "HPA051515: AB_2681517" "unprognostic (8.84e-2)" "unprognostic (7.57e-2)" "unprognostic (2.53e-2)" "unprognostic (9.43e-3)" "unprognostic (5.69e-1)" "unprognostic (1.07e-2)" "unprognostic (5.83e-3)" "unprognostic (2.16e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-2)" "unprognostic (2.23e-5)" "unprognostic (1.49e-2)" "unprognostic (4.08e-7)" "unprognostic (3.71e-2)" "unprognostic (3.69e-2)" "unprognostic (5.93e-2)" "unprognostic (9.06e-2)" NDST3 HSST3 ENSG00000164100 "N-deacetylase and N-sulfotransferase 3" O95803 4 118033618-118258634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.3;lymphoid tissue: 2.8;retina: 2.6" "Group enriched" "Detected in some" 7 "Excitatory neurons: 290.2;Inhibitory neurons: 123.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 1.4" "Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056189 Uncertain NA NA "Cluster 28: Neuronal - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 34: Neurons - Neuronal signaling" "HPA056189: AB_2683061" "unprognostic (1.95e-2)" "unprognostic (7.58e-2)" "unprognostic (4.34e-3)" "unprognostic (2.55e-7)" "unprognostic (4.05e-2)" "unprognostic (2.18e-2)" "unprognostic (2.86e-3)" "unprognostic (2.32e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-2)" "unprognostic (7.43e-2)" "unprognostic (1.99e-2)" "unprognostic (1.09e-3)" "unprognostic (1.37e-1)" "unprognostic (4.39e-3)" "unprognostic (6.83e-2)" "unprognostic (8.85e-2)" NDST4 ENSG00000138653 "N-deacetylase and N-sulfotransferase 4" Q9H3R1 4 114827763-115113876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal tubular cells: 6.1;Inhibitory neurons: 28.1;Microglial cells: 4.5;Oligodendrocyte precursor cells: 14.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 19.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 6.4;lymphoma: 2.5;Sarcoma: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011129 Uncertain NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA011129: AB_1079460" "unprognostic (5.58e-2)" "unprognostic (5.90e-2)" "unprognostic (4.82e-1)" "unprognostic (1.71e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.94e-1)" "unprognostic (6.55e-2)" SULT1A3 "STM, TL-PST" ENSG00000261052 "Sulfotransferase family 1A member 3" P0DMM9 16 30199228-30204310 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 232.9" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 22.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 64.6;intermediate monocyte: 55.7;myeloid DC: 35.2;non-classical monocyte: 26.8" "Group enriched" "Detected in all" 11 "dendritic cells: 35.2;monocytes: 64.6" "Low cancer specificity" "Detected in all" "HPA049500, HPA051051" Supported NA NA 160000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Small intestine - Absorption" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" 3 "HPA049500: AB_2680796, HPA051051: AB_2681327" "unprognostic (2.61e-1)" "unprognostic (1.72e-3)" "unprognostic (1.98e-3)" "unprognostic (4.98e-2)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (7.27e-2)" "unprognostic (2.09e-2)" "unprognostic (2.99e-2)" "unprognostic (2.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.18e-8)" "unprognostic (2.34e-2)" "unprognostic (2.51e-1)" "unprognostic (1.66e-1)" "unprognostic (9.48e-5)" SULT1B1 ST1B2 ENSG00000173597 "Sulfotransferase family 1B member 1" O43704 4 69721167-69787961 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 96.3;stomach 1: 43.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 295.5;Enteroendocrine cells: 53.8;Gastric mucus-secreting cells: 56.0;Paneth cells: 112.2;Proximal enterocytes: 223.7" "Group enriched" "Detected in some" 11 "colorectal cancer: 7.6;liver cancer: 2.6;pancreatic cancer: 5.5;stomach cancer: 5.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 10.6;neutrophil: 32.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 32.2" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Colon - Colon enterocytes, Prostate - Macrophages, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002107 Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 9: Non-specific - Receptor signaling" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 5: Enterocytes - Absorption" 7 "Golgi apparatus" Nucleoplasm "HPA002107: AB_2666542" "unprognostic (9.58e-2)" "unprognostic (4.05e-2)" "unprognostic (1.66e-2)" "unprognostic (1.16e-1)" "unprognostic (2.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.50e-1)" "unprognostic (4.77e-2)" "unprognostic (5.14e-2)" "unprognostic (8.78e-2)" "unprognostic (2.81e-2)" "unprognostic (3.27e-1)" "unprognostic (1.15e-3)" "unprognostic (1.89e-1)" "unprognostic (1.06e-2)" "unprognostic (6.93e-2)" "unprognostic (5.46e-2)" SULT1C2 "ST1C1, SULT1C1" ENSG00000198203 "Sulfotransferase family 1C member 2" O00338 2 108288639-108309915 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 68.4;stomach 1: 159.3" "Cell type enriched" "Detected in many" 8 "Gastric mucus-secreting cells: 517.6" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Region enriched" "Detected in many" 6 "choroid plexus: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 49.6;liver cancer: 20.1" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007190 Approved NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 46: Gastric mucus-secreting cells - Digestion" 1 "HPA007190: AB_1857647" "unprognostic (3.31e-2)" "unprognostic (1.63e-2)" "unprognostic (3.41e-1)" "unprognostic (2.14e-2)" "unprognostic (2.55e-1)" "unprognostic (3.33e-2)" "unprognostic (1.17e-3)" "unprognostic (3.61e-2)" "unprognostic (3.78e-1)" "unprognostic (3.62e-2)" "unprognostic (8.74e-2)" "unprognostic (2.76e-1)" "unprognostic (3.19e-2)" "unprognostic (9.27e-2)" "unprognostic (6.28e-2)" "unprognostic (4.63e-2)" "unprognostic (9.96e-5)" SULT1C4 "SULT1C, SULT1C2" ENSG00000198075 "Sulfotransferase family 1C member 4" O75897 2 108377911-108388989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 21.8;Cholangiocytes: 55.3;Endothelial cells: 21.5;Granulosa cells: 20.4;Lymphatic endothelial cells: 35.9;Muller glia cells: 21.2;Ovarian stromal cells: 34.2;Proximal tubular cells: 23.9" "Group enriched" "Detected in many" 6 "glioma: 7.1;renal cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Kidney cancer: 7.6;liver cancer: 21.8;Neuroblastoma: 14.0;testis cancer: 10.7" "Colon - Enteric glia cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Region enhanced" "Detected in all" "spinal cord: 51.1" HPA034530 Approved Cytosol NA NA "Cluster 64: Neuronal - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 6: Ovarian stromal cells - Transcription" Cytosol "HPA034530: AB_10670170" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-1)" "unprognostic (2.89e-1)" "unprognostic (5.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-2)" "unprognostic (5.77e-2)" "unprognostic (1.56e-3)" "unprognostic (1.68e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-3)" "prognostic favorable (9.99e-7)" "unprognostic (1.79e-2)" "unprognostic (2.96e-2)" "unprognostic (1.85e-2)" "unprognostic (1.38e-1)" SULT4A1 "hBR-STL-1, SULTX3" ENSG00000130540 "Sulfotransferase family 4A member 1" Q9BR01 22 43824509-43862513 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "brain: 107.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 19.2;Excitatory neurons: 51.4;Horizontal cells: 66.1;Inhibitory neurons: 52.9;Late spermatids: 34.9" "Cancer enhanced" "Detected in many" "testis cancer: 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Neuroblastoma: 6.4" "Colon - Colon enteroendocrine cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003129 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 4 "HPA003129: AB_1080130" "unprognostic (2.61e-3)" "unprognostic (1.05e-2)" "unprognostic (2.62e-1)" "unprognostic (6.30e-2)" "unprognostic (6.12e-3)" "unprognostic (1.32e-1)" "unprognostic (1.63e-1)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (2.48e-4)" "unprognostic (1.91e-2)" "unprognostic (6.10e-2)" "unprognostic (7.59e-4)" "unprognostic (7.89e-2)" "unprognostic (1.22e-1)" "unprognostic (8.20e-3)" "unprognostic (8.34e-3)" TOMT COMT2 ENSG00000284844 "Transmembrane O-methyltransferase" 11 72105924-72109596 "Metabolic proteins, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 11: Neuronal - Sensory perception" TPH1 "TPH, TPRH" ENSG00000129167 "Tryptophan hydroxylase 1" P17752 11 18017555-18046269 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Serotonin biosynthesis" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 6.6;intestine: 19.2;stomach 1: 14.9" "Cell type enriched" "Detected in many" 133 "Enteroendocrine cells: 1410.3" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.4" "Region enhanced" "Detected in all" "midbrain: 22.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 15.3" "Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB010767, HPA022483" Uncertain Uncertain Cytosol NA NA "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" 3 Cytosol "CAB010767: AB_261587, HPA022483: AB_1858378" "unprognostic (2.14e-4)" "unprognostic (9.97e-2)" "unprognostic (6.92e-2)" "unprognostic (6.78e-2)" "unprognostic (1.55e-1)" "unprognostic (6.26e-5)" "unprognostic (1.73e-1)" "unprognostic (5.33e-2)" "unprognostic (1.60e-1)" "unprognostic (2.12e-2)" "unprognostic (1.19e-4)" "unprognostic (6.72e-2)" "unprognostic (5.40e-8)" "unprognostic (3.76e-2)" "unprognostic (7.42e-2)" "unprognostic (3.10e-1)" "unprognostic (2.46e-5)" TPH2 "FLJ37295, NTPH" ENSG00000139287 "Tryptophan hydroxylase 2" Q8IWU9 12 71938845-72186618 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Serotonin biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Early spermatids: 7.6;Inhibitory neurons: 3.1;Late spermatids: 6.8;Oocytes: 2.2;Spermatogonia: 2.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "midbrain: 631.8;pons: 271.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 2.3" "Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 31 "midbrain: 106.7;pons and medulla: 34.9" "Group enriched" "Detected in some" 5 "midbrain: 63.3;pons: 62.2" CAB078198 Enhanced NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 65: Non-specific - Unknown function" "Cluster 11: Late spermatids - Unknown function" "CAB078198: AB_2665804" "unprognostic (1.19e-1)" "unprognostic (6.01e-1)" "unprognostic (3.46e-2)" "unprognostic (2.31e-1)" "unprognostic (5.91e-2)" "unprognostic (2.02e-1)" "unprognostic (5.01e-2)" "unprognostic (7.32e-2)" "unprognostic (1.34e-1)" UST 2OST ENSG00000111962 "Uronyl 2-sulfotransferase" Q9Y2C2 6 148747030-149076990 "Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 318.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032022 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA032022: AB_10603326" "unprognostic (3.43e-1)" "unprognostic (1.90e-1)" "unprognostic (7.87e-3)" "unprognostic (3.22e-5)" "unprognostic (1.83e-3)" "unprognostic (1.50e-1)" "unprognostic (5.71e-2)" "unprognostic (1.96e-2)" "unprognostic (8.31e-3)" "unprognostic (2.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.11e-1)" "unprognostic (9.25e-3)" "unprognostic (9.48e-2)" "unprognostic (1.07e-1)" "unprognostic (2.51e-2)" "unprognostic (3.02e-2)"