Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABCB10 "EST20237, M-ABC2, MTABC2" ENSG00000135776 "ATP binding cassette subfamily B member 10" Q9NRK6 1 229516582-229558707 "Plasma proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 59.3" "Cell type enriched" "Detected in many" 5 "Erythroid cells: 147.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB044063, CAB044065, HPA055175" Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 6: Bone marrow - Innate immune response" "Cluster 15: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 1: Erythroid cells - Oxygen transport" "CAB044063: AB_353262, CAB044065: AB_2220666, HPA055175: AB_2682727" "unprognostic (1.00e-1)" "unprognostic (1.29e-2)" "unprognostic (5.56e-3)" "unprognostic (5.64e-2)" "unprognostic (2.04e-1)" "unprognostic (8.06e-3)" "unprognostic (9.38e-2)" "unprognostic (2.05e-1)" "unprognostic (4.15e-2)" "unprognostic (5.61e-2)" "unprognostic (2.81e-1)" "unprognostic (3.13e-1)" "unprognostic (8.32e-2)" "unprognostic (2.58e-1)" "unprognostic (3.83e-1)" "unprognostic (5.29e-2)" "unprognostic (3.37e-2)" ABCB7 "ABC7, ASAT, Atm1p, EST140535" ENSG00000131269 "ATP binding cassette subfamily B member 7" O75027 X 75051048-75156732 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034982 Approved Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 35: Non-specific - Mitochondria" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034982: AB_10601010" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (1.49e-2)" "unprognostic (1.83e-3)" "unprognostic (4.44e-3)" "unprognostic (1.33e-2)" "unprognostic (6.31e-2)" "unprognostic (4.39e-2)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" "unprognostic (4.14e-2)" "unprognostic (2.55e-2)" "prognostic favorable (5.31e-6)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" ABCC4 "EST170205, MOAT-B, MOATB, MRP4" ENSG00000125257 "ATP binding cassette subfamily C member 4" O15439 13 95019835-95301475 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 39.8" "Cell type enriched" "Detected in many" 4 "Microglial cells: 194.1" "Cancer enriched" "Detected in all" 8 "prostate cancer: 90.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "prostate cancer: 68.3" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002476 Enhanced Supported "Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 21: Non-specific - Metabolism" "Cluster 49: HMC-1 - Innate immune response" "Cluster 57: Platelets - Hemostasis" 1 "Plasma membrane" "Nucleoli, Golgi apparatus" "HPA002476: AB_1844434" "unprognostic (8.77e-2)" "unprognostic (1.94e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.89e-4)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (7.45e-3)" "unprognostic (2.40e-2)" "unprognostic (9.96e-2)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.55e-2)" "prognostic favorable (2.25e-10)" "unprognostic (7.44e-3)" "unprognostic (1.67e-1)" "unprognostic (5.55e-2)" "unprognostic (2.35e-2)" ABCG2 "ABCP, BCRP, CD338, EST157481, MXR" ENSG00000118777 "ATP binding cassette subfamily G member 2 (Junior blood group)" Q9UNQ0 4 88090150-88231628 "Cancer-related genes, CD markers, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 85.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 198.2;Distal enterocytes: 98.5;Extravillous trophoblasts: 89.8;Hofbauer cells: 125.1;Microglial cells: 177.1;Proximal enterocytes: 212.5" "Cancer enhanced" "Detected in many" "glioma: 9.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037299, HPA054719" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 "Plasma membrane" Nucleoplasm "CAB037299: AB_476804, HPA054719: " "unprognostic (5.04e-1)" "unprognostic (3.05e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-1)" "unprognostic (1.01e-3)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.14e-2)" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (4.52e-2)" "unprognostic (1.67e-3)" "unprognostic (8.82e-3)" "unprognostic (7.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.92e-1)" ABCG5 STSL ENSG00000138075 "ATP binding cassette subfamily G member 5" Q9H222 2 43812472-43838865 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "intestine: 46.4;liver: 60.5" "Group enriched" "Detected in some" 4 "Hepatocytes: 48.1;Paneth cells: 20.8;Proximal enterocytes: 31.4" "Cancer enriched" "Detected in some" 23 "liver cancer: 11.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 43: Hepatocytes - Metabolism" "unprognostic (1.71e-1)" "unprognostic (5.47e-2)" "unprognostic (4.01e-1)" "unprognostic (6.92e-2)" "unprognostic (2.24e-1)" "unprognostic (9.97e-2)" "prognostic favorable (2.60e-5)" "unprognostic (4.59e-2)" "unprognostic (3.10e-1)" "unprognostic (1.38e-3)" "unprognostic (3.07e-4)" "unprognostic (1.86e-1)" "unprognostic (3.07e-1)" "unprognostic (5.52e-3)" "unprognostic (8.29e-2)" "unprognostic (5.31e-2)" "unprognostic (3.08e-2)" ACER3 "APHC, FLJ11238, PHCA" ENSG00000078124 "Alkaline ceramidase 3" Q9NUN7 11 76860859-77026797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 182.8;Oligodendrocyte precursor cells: 149.5;Oligodendrocytes: 311.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070087 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA070087: AB_2732147" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (9.54e-3)" "unprognostic (1.37e-1)" "unprognostic (4.06e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (7.13e-2)" "unprognostic (2.35e-3)" "unprognostic (8.45e-3)" "unprognostic (1.30e-1)" "unprognostic (3.68e-3)" "prognostic unfavorable (2.73e-4)" "unprognostic (5.24e-2)" "unprognostic (3.37e-1)" "unprognostic (9.88e-2)" "unprognostic (7.97e-2)" ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449090 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.0;heart muscle: 102.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 92.9;Horizontal cells: 37.8;Inhibitory neurons: 42.1;Oligodendrocytes: 83.5;Oocytes: 45.6;Paneth cells: 54.4;Peritubular cells: 70.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 8.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in all" 5 "basal ganglia: 388.1" "Region enriched" "Detected in all" 6 "basal ganglia: 206.2" "HPA017730, HPA077682" Uncertain Approved Vesicles NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" Vesicles "HPA017730: AB_1844595, HPA077682: AB_2686851" "unprognostic (3.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.61e-3)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-2)" "unprognostic (1.48e-1)" "unprognostic (7.61e-2)" "unprognostic (2.49e-2)" "unprognostic (2.34e-1)" "unprognostic (7.27e-3)" "unprognostic (2.64e-2)" "prognostic favorable (7.46e-6)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (3.19e-2)" "unprognostic (5.97e-4)" ADCY7 "AC7, KIAA0037" ENSG00000121281 "Adenylate cyclase 7" P51828 16 50246137-50318135 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 42.0;Kupffer cells: 60.4;Langerhans cells: 55.6;Macrophages: 46.7;Microglial cells: 50.1;monocytes: 50.3;NK-cells: 59.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041218, HPA048241" Uncertain Approved "Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "HPA041218: AB_2677365, HPA048241: AB_2680326" "unprognostic (1.98e-1)" "prognostic unfavorable (5.31e-4)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (3.77e-1)" "unprognostic (2.80e-1)" "unprognostic (3.90e-2)" "unprognostic (7.75e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.59e-3)" "unprognostic (7.34e-2)" "unprognostic (2.15e-3)" "unprognostic (2.18e-1)" "unprognostic (9.52e-4)" ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 21.0;liver: 58.3" "Cell type enhanced" "Detected in some" "Astrocytes: 100.0;Early spermatids: 34.5;Inhibitory neurons: 117.6;Late spermatids: 38.2;Oligodendrocyte precursor cells: 107.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Bone cancer: 4.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 3 Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" ADTRP "AIG1L, C6orf105, dJ413H6.1" ENSG00000111863 "Androgen dependent TFPI regulating protein" Q96IZ2 6 11712054-11807046 "Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 100.6;intestine: 95.7;parathyroid gland: 89.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 99.6;Distal tubular cells: 76.8;Early spermatids: 132.7;Late spermatids: 185.1;Paneth cells: 58.0;Proximal enterocytes: 128.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 10 "choroid plexus: 79.3" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 14.8;T-reg: 13.6" "Lineage enriched" "Detected in many" 5 "T-cells: 14.8" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA048113 Uncertain Uncertain Nucleoli NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 5: Enterocytes - Absorption" 2 Nucleoli "HPA048113: AB_2680268" "unprognostic (6.82e-3)" "unprognostic (1.41e-1)" "unprognostic (1.58e-1)" "unprognostic (8.14e-3)" "unprognostic (3.04e-3)" "unprognostic (1.41e-2)" "unprognostic (4.00e-2)" "unprognostic (1.77e-1)" "unprognostic (1.85e-2)" "unprognostic (2.72e-1)" "unprognostic (5.41e-3)" "unprognostic (2.90e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (2.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.95e-2)" "unprognostic (1.26e-1)" ALG9 DIBD1 ENSG00000086848 "ALG9 alpha-1,2-mannosyltransferase" Q9H6U8 11 111782195-111871581 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 25.7;Inhibitory neurons: 30.5;Oligodendrocytes: 29.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038575 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 15: Pancreas - Proteolysis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" "Endoplasmic reticulum" "HPA038575: AB_10672718" "unprognostic (1.48e-1)" "unprognostic (5.39e-2)" "unprognostic (6.22e-2)" "unprognostic (5.34e-3)" "unprognostic (8.72e-2)" "unprognostic (2.90e-1)" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (7.07e-3)" "unprognostic (5.11e-2)" "unprognostic (8.75e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (7.29e-5)" "unprognostic (9.15e-2)" "unprognostic (7.76e-2)" "unprognostic (4.20e-2)" "unprognostic (1.10e-2)" AMFR "gp78, RNF45" ENSG00000159461 "Autocrine motility factor receptor" Q9UKV5 16 56361452-56425545 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ubl conjugation pathway, Wnt signaling pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 155.3;Hepatocytes: 133.9;Late spermatids: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026381, HPA029018, HPA064339, HPA077835" Approved Supported "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 62: Hepatocytes - Metabolism" 12 "Endoplasmic reticulum, Golgi apparatus" "CAB026381: , HPA029018: AB_2672869, HPA064339: , HPA077835: AB_2686856" "unprognostic (1.72e-2)" "unprognostic (1.62e-1)" "unprognostic (1.62e-2)" "unprognostic (2.43e-2)" "unprognostic (3.60e-3)" "unprognostic (6.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-3)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (4.16e-2)" "unprognostic (5.52e-3)" "unprognostic (1.45e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (2.28e-1)" APH1B "APH-1B, DKFZp564D0372, PSFL" ENSG00000138613 "Aph-1 homolog B, gamma-secretase subunit" Q8WW43 15 63276018-63309126 "Predicted membrane proteins, Transporters" "Notch signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 119.4" "Cell type enhanced" "Detected in many" "Early spermatids: 1691.7;Late spermatids: 396.0;Spermatocytes: 693.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 108.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Testis - Spermatogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 2 "unprognostic (9.92e-2)" "unprognostic (1.03e-2)" "unprognostic (1.49e-1)" "unprognostic (1.75e-1)" "unprognostic (3.55e-2)" "unprognostic (3.57e-1)" "unprognostic (7.86e-2)" "unprognostic (1.78e-1)" "unprognostic (3.86e-1)" "unprognostic (4.56e-2)" "prognostic favorable (1.05e-4)" "unprognostic (8.44e-2)" "prognostic favorable (2.25e-4)" "unprognostic (4.29e-3)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" AQP1 "CHIP28, CO" ENSG00000240583 "Aquaporin 1 (Colton blood group)" P29972 7 30911853-30925517 "Blood group antigen proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 786.7" "Group enriched" "Detected in many" 6 "Adipocytes: 881.1;Alveolar cells type 1: 406.1;Alveolar cells type 2: 408.7;Cholangiocytes: 333.9;Endothelial cells: 689.9;Mesothelial cells: 636.1;Proximal tubular cells: 237.1" "Cancer enhanced" "Detected in all" "glioma: 336.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 50.3" "Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Region enriched" "Detected in many" 5 "olfactory bulb: 46.6" "Region enriched" "Detected in many" 4 "spinal cord: 29.0" "CAB001707, HPA019206" Enhanced Supported "Plasma membrane" NA NA 49000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 22: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 106 "Plasma membrane" "CAB001707: , HPA019206: AB_1844965" "unprognostic (4.18e-2)" "unprognostic (7.82e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "prognostic favorable (6.52e-4)" "unprognostic (1.95e-3)" "unprognostic (1.66e-1)" "unprognostic (3.00e-2)" "unprognostic (3.80e-2)" "unprognostic (4.16e-1)" "unprognostic (2.05e-2)" "prognostic favorable (1.32e-8)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (7.21e-2)" AQP10 ENSG00000143595 "Aquaporin 10" Q96PS8 1 154321090-154325325 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 66.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Ciliated cells: 2.7;Erythroid cells: 1.1;granulocytes: 5.0;Sertoli cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 1.5;Neuroblastoma: 1.1" "Testis - Sertoli cells" "Not detected" "Not detected" "HPA062621, HPA065947" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 17 "Plasma membrane" Vesicles "HPA062621: , HPA065947: AB_2685584" "unprognostic (6.84e-2)" "unprognostic (4.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (8.45e-4)" "unprognostic (1.63e-1)" "unprognostic (3.07e-1)" "unprognostic (4.08e-2)" "unprognostic (3.99e-1)" "unprognostic (1.22e-1)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (7.64e-3)" AQP2 ENSG00000167580 "Aquaporin 2" P41181 12 49950737-49958878 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Diabetes insipidus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 91 "kidney: 373.4;seminal vesicle: 205.2" "Cell type enriched" "Detected in some" 17 "Collecting duct cells: 3224.6" "Group enriched" "Detected in some" 6 "renal cancer: 1.7;stomach cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.1;Gastric cancer: 1.2" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA046834 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 3: Basal prostatic cells - Lipid metabolism" 33 "HPA046834: AB_2679830" "unprognostic (2.10e-1)" "unprognostic (3.77e-2)" "unprognostic (6.96e-3)" "unprognostic (4.48e-3)" "unprognostic (3.60e-2)" "unprognostic (9.51e-2)" "unprognostic (2.21e-1)" "unprognostic (1.43e-2)" "unprognostic (2.65e-2)" "unprognostic (7.38e-3)" "unprognostic (5.92e-2)" "unprognostic (4.60e-2)" "unprognostic (2.01e-2)" "unprognostic (1.11e-1)" AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1483.2;skin 1: 563.9;urinary bladder: 662.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1556.2;Basal squamous epithelial cells: 1011.0;Collecting duct cells: 1073.6;Squamous epithelial cells: 2365.1;Suprabasal keratinocytes: 2153.4" "Group enriched" "Detected in all" 5 "cervical cancer: 319.0;head and neck cancer: 283.7;lung cancer: 146.8;urothelial cancer: 221.3" "Region enhanced" "Detected in all" "pons: 47.2" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 182.0;T-reg: 205.9" "Lineage enriched" "Detected in many" 18 "T-cells: 205.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 403.6" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 23 "Plasma membrane" "HPA014924: AB_2669120" "unprognostic (4.29e-2)" "prognostic favorable (5.31e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-2)" "unprognostic (1.11e-2)" "unprognostic (9.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.46e-1)" "unprognostic (9.06e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (4.51e-2)" AQP4 "AQP-4, hAQP4, MIWC" ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 367.2;lung: 111.3" "Group enriched" "Detected in many" 11 "Alveolar cells type 1: 422.7;Alveolar cells type 2: 333.2;Astrocytes: 462.6;Muller glia cells: 197.3" "Cancer enriched" "Detected in some" 22 "glioma: 223.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain cancer: 2.5;Rhabdoid: 1.7" "Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Alveolar cells - Lung function" 2 "Plasma membrane" "Cell Junctions" "CAB005079: AB_2274338, CAB058689: AB_2665579, HPA014784: AB_1844967" "unprognostic (7.23e-5)" "unprognostic (1.55e-1)" "unprognostic (3.19e-8)" "unprognostic (3.68e-1)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.34e-1)" "unprognostic (5.38e-3)" "unprognostic (1.64e-3)" "unprognostic (8.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.10e-2)" AQP5 ENSG00000161798 "Aquaporin 5" P55064 12 49961872-49965682 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 604.8;testis: 215.9" "Group enriched" "Detected in many" 6 "Early spermatids: 1377.0;Late spermatids: 4261.2;Serous glandular cells: 1171.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 87.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 57.1;Gastric cancer: 24.2" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065008 Enhanced Approved "Plasma membrane" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 75: Serous glandular cells - Salivary secretion" 5 "Plasma membrane" "HPA065008: AB_2685401" "unprognostic (4.67e-3)" "unprognostic (5.00e-2)" "unprognostic (3.30e-1)" "unprognostic (6.00e-3)" "unprognostic (1.92e-3)" "prognostic favorable (1.75e-5)" "unprognostic (4.13e-3)" "unprognostic (1.02e-2)" "unprognostic (9.39e-2)" "unprognostic (3.70e-3)" "unprognostic (2.88e-3)" "unprognostic (2.46e-3)" "unprognostic (1.69e-4)" "unprognostic (2.53e-1)" "unprognostic (5.28e-2)" "unprognostic (2.51e-3)" "unprognostic (9.11e-3)" AQP6 AQP2L ENSG00000086159 "Aquaporin 6" Q13520 12 49967194-49977139 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "kidney: 51.2" "Cell type enhanced" "Detected in some" "Astrocytes: 4.0;Club cells: 1.5;Collecting duct cells: 1.9;Distal tubular cells: 3.1;Ionocytes: 5.5;Oligodendrocyte precursor cells: 1.4;Oligodendrocytes: 1.5" "Cancer enriched" "Detected in many" 9 "renal cancer: 9.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells (progenitors), Liver - Hepatocytes, Skin - Eccrine sweat gland cells" "Region enriched" "Detected in some" 7 "cerebellum: 21.0" "Not detected" "Not detected" HPA015278 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 264 "HPA015278: AB_10600982" "unprognostic (1.23e-1)" "unprognostic (1.32e-2)" "unprognostic (9.53e-2)" "unprognostic (2.02e-2)" "unprognostic (6.46e-2)" "unprognostic (4.60e-3)" "unprognostic (3.45e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.74e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.03e-2)" "unprognostic (1.77e-1)" AQP7 "AQP7L, AQP9, AQPap" ENSG00000165269 "Aquaporin 7" O14520 9 33383179-33402682 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 205.9;breast: 101.5;heart muscle: 105.1" "Cell type enhanced" "Detected in many" "Adipocytes: 105.7;Cardiomyocytes: 87.0;Early spermatids: 152.5;Proximal enterocytes: 143.0;Proximal tubular cells: 53.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 1 "unprognostic (3.25e-2)" "unprognostic (3.81e-3)" "unprognostic (1.25e-5)" "unprognostic (7.22e-3)" "unprognostic (1.50e-1)" "unprognostic (3.32e-1)" "unprognostic (4.67e-2)" "unprognostic (3.06e-2)" "unprognostic (9.99e-2)" "unprognostic (4.65e-2)" "unprognostic (8.56e-4)" "unprognostic (1.21e-1)" "prognostic favorable (9.21e-8)" "unprognostic (2.42e-1)" "unprognostic (1.28e-1)" "unprognostic (1.61e-1)" "unprognostic (2.12e-3)" AQP7B ENSG00000259916 "Aquaporin 7B" 2 94587101-94612744 "Metabolic proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 11 "adipose tissue: 30.5" "Group enriched" "Detected in some" 4 "Astrocytes: 4.3;Early spermatids: 2.3;Excitatory neurons: 2.3;Inhibitory neurons: 1.1;Late spermatids: 2.3;Proximal tubular cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (8.07e-3)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.15e-1)" "unprognostic (9.15e-3)" "unprognostic (6.22e-2)" "unprognostic (4.66e-2)" AQP9 "HsT17287, SSC1" ENSG00000103569 "Aquaporin 9" O43315 15 58138169-58185911 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 681.6" "Cell type enhanced" "Detected in some" "Hepatocytes: 277.8;Hofbauer cells: 71.4;Kupffer cells: 51.3;Macrophages: 89.1;monocytes: 342.1" "Cancer enriched" "Detected in many" 30 "liver cancer: 132.4" "Region enhanced" "Detected in many" "cerebral cortex: 28.1" "Immune cell enriched" "Detected in many" 20 "neutrophil: 1165.9" "Lineage enriched" "Detected in many" 20 "granulocytes: 1165.9" "Cancer enriched" "Detected in single" 9 "lymphoma: 9.0" "Adipose subcutaneous - Macrophages, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Hepatocytes, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Skin - Keratinocyte (granular), Stomach - Neutrophils, Thyroid - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA074762, CAB075684" Enhanced NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 18 "CAB075684: , HPA074762: AB_2732267" "unprognostic (1.91e-1)" "unprognostic (1.92e-1)" "unprognostic (7.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.24e-2)" "unprognostic (4.15e-2)" "unprognostic (1.36e-3)" "unprognostic (2.28e-2)" "unprognostic (3.82e-2)" "unprognostic (2.03e-1)" "unprognostic (4.80e-3)" "unprognostic (6.98e-2)" "prognostic unfavorable (5.72e-11)" "unprognostic (8.78e-2)" "unprognostic (1.13e-2)" "unprognostic (1.25e-1)" "unprognostic (8.39e-2)" ARL6IP1 "AIP1, ARL6IP, ARMER, KIAA0069, SPG61" ENSG00000170540 "ADP ribosylation factor like GTPase 6 interacting protein 1" Q15041 16 18791669-18801572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA045307 Uncertain Supported "Endoplasmic reticulum" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 52: Non-specific - Cell proliferation" 60 "Endoplasmic reticulum" "HPA045307: AB_10961042" "unprognostic (2.42e-1)" "unprognostic (3.47e-2)" "unprognostic (4.07e-3)" "unprognostic (1.12e-1)" "unprognostic (1.54e-1)" "unprognostic (2.60e-3)" "unprognostic (2.58e-2)" "unprognostic (1.76e-2)" "unprognostic (3.88e-2)" "unprognostic (6.83e-2)" "unprognostic (1.91e-3)" "unprognostic (3.33e-2)" "unprognostic (1.13e-2)" "unprognostic (7.09e-2)" "unprognostic (4.60e-2)" "unprognostic (6.32e-3)" "unprognostic (5.36e-3)" ATG9A "APG9L1, FLJ22169" ENSG00000198925 "Autophagy related 9A" Q7Z3C6 2 219219380-219229717 "Predicted membrane proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Excitatory neurons: 14.7;Inhibitory neurons: 13.5;Oligodendrocyte precursor cells: 9.0;Oligodendrocytes: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059551 Uncertain Supported Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 79: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 49: Non-specific - Transcription" 11 Vesicles "HPA059551: AB_2684060" "unprognostic (1.53e-2)" "unprognostic (4.03e-1)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (4.80e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (8.99e-3)" "unprognostic (2.07e-1)" "unprognostic (3.55e-3)" "unprognostic (4.67e-2)" "unprognostic (4.21e-1)" "unprognostic (2.23e-2)" "unprognostic (4.84e-2)" "unprognostic (3.15e-1)" "unprognostic (5.61e-2)" "unprognostic (1.95e-2)" ATG9B "APG9L2, FLJ14885, NOS3AS, SONE" ENSG00000181652 "Autophagy related 9B" Q674R7 7 151012209-151024499 "Metabolic proteins, Predicted membrane proteins, Transporters" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 4.0;placenta: 4.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 28.5;Early spermatids: 63.1;Late spermatids: 26.6;Syncytiotrophoblasts: 147.9" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" "unprognostic (1.59e-1)" "unprognostic (2.18e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (1.53e-3)" "unprognostic (1.05e-3)" "unprognostic (2.79e-3)" "unprognostic (6.66e-2)" "unprognostic (2.38e-3)" "unprognostic (6.76e-2)" "unprognostic (2.02e-1)" "unprognostic (5.06e-2)" "unprognostic (2.08e-6)" "unprognostic (2.82e-2)" "unprognostic (2.70e-2)" "unprognostic (6.34e-2)" "unprognostic (2.63e-1)" ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690038-112887168 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Deafness, Disease variant, Leukodystrophy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 207.7;Alveolar cells type 2: 217.0;Cone photoreceptor cells: 107.0;Glandular and luminal cells: 150.6;Oligodendrocytes: 128.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Prostate - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Alveolar cells - Lung function" 1 Vesicles "Golgi apparatus" "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" ATP2B2 PMCA2 ENSG00000157087 "ATPase plasma membrane Ca2+ transporting 2" Q01814 3 10324023-10708007 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.5;choroid plexus: 62.8;salivary gland: 32.2;skeletal muscle: 36.1" "Cell type enhanced" "Detected in many" "Astrocytes: 111.5;Bipolar cells: 80.9;Excitatory neurons: 312.4;Horizontal cells: 87.5;Inhibitory neurons: 221.2;Oligodendrocyte precursor cells: 54.7" "Cancer enhanced" "Detected in some" "liver cancer: 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.7;Neuroblastoma: 3.3" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005606 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 18: Liver cancer - Metabolism" "Cluster 34: Neurons - Neuronal signaling" 1 "CAB005606: AB_2243199" "unprognostic (2.04e-1)" "unprognostic (1.26e-2)" "unprognostic (6.84e-2)" "unprognostic (1.59e-2)" "unprognostic (3.59e-1)" "unprognostic (3.62e-1)" "unprognostic (4.09e-2)" "unprognostic (4.65e-1)" "unprognostic (5.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.32e-4)" "unprognostic (2.70e-1)" "unprognostic (1.46e-3)" "unprognostic (1.08e-3)" "unprognostic (1.33e-2)" "unprognostic (8.34e-2)" "unprognostic (7.95e-3)" ATP7A MNK ENSG00000165240 "ATPase copper transporting alpha" Q04656 X 77910690-78050395 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012887, HPA048107" Approved Supported "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 55: Non-specific - Transcription" 2 "Golgi apparatus" "HPA012887: AB_1845205, HPA048107: AB_2680266" "unprognostic (3.14e-2)" "unprognostic (3.48e-1)" "unprognostic (4.90e-2)" "unprognostic (1.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-3)" "unprognostic (2.59e-2)" "unprognostic (3.17e-2)" "unprognostic (2.47e-1)" "unprognostic (2.30e-2)" "unprognostic (1.14e-1)" "prognostic favorable (8.38e-4)" "unprognostic (1.06e-1)" "unprognostic (2.16e-1)" "unprognostic (3.69e-1)" "unprognostic (2.52e-1)" ATP7B WND ENSG00000123191 "ATPase copper transporting beta" P35670 13 51930436-52012125 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.6;Early spermatids: 43.9;Late spermatids: 84.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009137, HPA013187" Supported Supported "Golgi apparatus" NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 "Golgi apparatus" "HPA009137: AB_2668214, HPA013187: AB_1845206" "unprognostic (1.13e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.01e-4)" "unprognostic (3.49e-1)" "unprognostic (5.51e-2)" "unprognostic (1.55e-2)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (5.77e-2)" "unprognostic (8.29e-2)" "unprognostic (1.17e-1)" "unprognostic (3.26e-3)" "unprognostic (4.66e-2)" "unprognostic (3.54e-1)" "unprognostic (6.21e-3)" "unprognostic (1.40e-1)" AVPR2 "DIR, DIR3, V2R" ENSG00000126895 "Arginine vasopressin receptor 2" P30518 X 153902531-153907166 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes insipidus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.6;kidney: 10.7" "Group enriched" "Detected in some" 7 "Adipocytes: 46.0;Collecting duct cells: 40.8;Endothelial cells: 17.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 9.3" "Group enriched" "Detected in some" 28 "intermediate monocyte: 3.5;non-classical monocyte: 3.2" "Lineage enriched" "Detected in single" 30 "monocytes: 3.5" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 5.3" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 29 "cerebellum: 10.5" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 70: DU4475 - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "unprognostic (3.05e-2)" "unprognostic (5.62e-2)" "unprognostic (1.99e-4)" "unprognostic (2.50e-4)" "unprognostic (2.76e-1)" "unprognostic (7.10e-6)" "unprognostic (3.80e-3)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-2)" "unprognostic (4.21e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-2)" "unprognostic (1.87e-1)" "unprognostic (4.38e-1)" "unprognostic (9.83e-2)" BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96256210-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 22.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 36.0;Basal squamous epithelial cells: 29.9;Mesothelial cells: 25.2;Squamous epithelial cells: 20.4;Suprabasal keratinocytes: 23.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in single" HPA002935 Approved NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA002935: AB_1078274" "unprognostic (6.15e-2)" "unprognostic (2.78e-2)" "unprognostic (9.40e-2)" "unprognostic (3.06e-3)" "unprognostic (6.76e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-2)" "unprognostic (2.34e-3)" "unprognostic (2.23e-2)" "unprognostic (2.96e-2)" "unprognostic (4.80e-3)" "unprognostic (2.36e-1)" "unprognostic (9.96e-6)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-3)" "unprognostic (4.66e-2)" CACNA1A "APCA, CACNL1A4, Cav2.1, EA2, FHM, HPCA, MHP, MHP1, SCA6" ENSG00000141837 "Calcium voltage-gated channel subunit alpha1 A" O00555 19 13206442-13633025 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "brain: 240.4" "Group enriched" "Detected in many" 7 "Bipolar cells: 145.9;Enteroendocrine cells: 228.5;Excitatory neurons: 307.8;Horizontal cells: 429.9;Inhibitory neurons: 356.4;Oligodendrocyte precursor cells: 255.2" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "cerebellum: 218.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.2;lung cancer: 8.4;Rhabdoid: 8.2" "Pancreas - Alpha cells, Pancreas - Beta cells, Skeletal muscle - Smooth muscle cells, Stomach - Gastric enteroendocrine cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064258, HPA068138, HPA071902" Enhanced Supported Uncertain "Endoplasmic reticulum" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 18 "Endoplasmic reticulum" "HPA064258: AB_2685229, HPA068138: , HPA071902: " "unprognostic (1.09e-1)" "unprognostic (3.73e-3)" "unprognostic (2.27e-1)" "unprognostic (2.78e-4)" "unprognostic (4.00e-2)" "unprognostic (2.29e-3)" "unprognostic (5.47e-2)" "unprognostic (3.13e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-2)" "prognostic favorable (4.32e-4)" "unprognostic (5.31e-3)" "unprognostic (5.03e-6)" "unprognostic (6.29e-2)" "unprognostic (1.59e-1)" "unprognostic (2.61e-2)" "unprognostic (6.25e-2)" CACNA1C "CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS" ENSG00000151067 "Calcium voltage-gated channel subunit alpha1 C" Q13936 12 1970772-2697950 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Host-virus interaction, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Brugada syndrome, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 19.5;heart muscle: 20.2;intestine: 28.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 586.4;Inhibitory neurons: 456.6;Oligodendrocyte precursor cells: 182.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.9" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039796, CAB079031" Enhanced Approved NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" 3 "CAB079031: , HPA039796: AB_10673019" "unprognostic (1.76e-1)" "unprognostic (1.19e-1)" "unprognostic (6.29e-2)" "unprognostic (9.35e-2)" "unprognostic (3.71e-2)" "unprognostic (1.60e-2)" "unprognostic (4.68e-2)" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (1.03e-5)" "unprognostic (1.93e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-7)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (6.90e-2)" "unprognostic (3.39e-2)" CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181813262 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 16.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 182.2;Inhibitory neurons: 110.6;Oligodendrocyte precursor cells: 69.3;Oligodendrocytes: 31.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.4;lung cancer: 2.0" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Lung - Neutrophil_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.96e-3)" "unprognostic (1.89e-1)" "unprognostic (1.05e-2)" "unprognostic (1.54e-5)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (9.48e-3)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.85e-7)" "unprognostic (1.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" CATSPER2 ENSG00000166762 "Cation channel sperm associated 2" Q96P56 15 43628503-43668118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.4;testis: 15.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 81.6;Early spermatids: 75.3;Horizontal cells: 40.9;Rod photoreceptor cells: 171.5;Spermatocytes: 65.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 2: Neurons - Nucleosome" "Cluster 56: Non-specific - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" 1 "unprognostic (6.88e-3)" "unprognostic (6.79e-2)" "unprognostic (2.08e-2)" "unprognostic (2.65e-2)" "unprognostic (4.05e-1)" "unprognostic (1.05e-2)" "unprognostic (7.11e-3)" "unprognostic (1.48e-2)" "unprognostic (6.35e-2)" "unprognostic (1.15e-2)" "unprognostic (1.09e-2)" "unprognostic (3.37e-2)" "unprognostic (3.74e-3)" "unprognostic (1.15e-1)" "unprognostic (6.04e-2)" "unprognostic (8.87e-2)" "unprognostic (8.23e-5)" CATSPER4 ENSG00000188782 "Cation channel sperm associated 4" Q7RTX7 1 26190561-26202968 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 53 "testis: 10.9" "Cell type enriched" "Detected in some" 8 "Early spermatids: 90.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA045257 Enhanced NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 18: Early spermatids - Unknown function" 1 "HPA045257: AB_10968995" "unprognostic (7.20e-2)" "unprognostic (2.06e-2)" "unprognostic (4.56e-2)" "unprognostic (2.69e-2)" "unprognostic (3.49e-1)" "unprognostic (3.86e-2)" "unprognostic (1.52e-2)" "unprognostic (2.16e-1)" "unprognostic (3.06e-1)" "unprognostic (6.78e-2)" "unprognostic (6.98e-2)" "unprognostic (6.67e-5)" CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353864-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.8" "Group enriched" "Detected in some" 4 "dendritic cells: 60.6;Kupffer cells: 47.0;Langerhans cells: 16.5;Macrophages: 21.7;Plasma cells: 31.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 557.4" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Myeloma: 29.9" "Breast - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: AB_344889, HPA063255: " "unprognostic (1.09e-2)" "unprognostic (6.28e-4)" "unprognostic (3.49e-2)" "unprognostic (6.35e-4)" "unprognostic (1.89e-2)" "unprognostic (4.16e-4)" "unprognostic (8.06e-2)" "prognostic favorable (5.87e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (4.88e-2)" "unprognostic (4.19e-1)" CERS1 "LAG1, LASS1, UOG1" ENSG00000223802 "Ceramide synthase 1" P27544 19 18868545-18896727 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 166.6" "Cell type enriched" "Detected in some" 8 "Late spermatids: 119.0" "Group enriched" "Detected in many" 5 "glioma: 13.5;melanoma: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Pancreas - Alpha cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" HPA045724 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Late spermatids - Unknown function" "Endoplasmic reticulum" "HPA045724: AB_10969762" "unprognostic (8.25e-2)" "unprognostic (8.91e-2)" "unprognostic (2.12e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-2)" "unprognostic (6.47e-2)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "unprognostic (4.02e-1)" "unprognostic (7.04e-3)" "unprognostic (3.52e-3)" "unprognostic (1.92e-1)" "unprognostic (4.59e-2)" "unprognostic (2.99e-2)" "unprognostic (3.15e-2)" "unprognostic (9.15e-2)" "unprognostic (3.49e-1)" CERS2 "FLJ10243, LASS2, SP260" ENSG00000143418 "Ceramide synthase 2" Q96G23 1 150960583-150975003 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 709.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 167.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027262, HPA078737" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 62: Hepatocytes - Metabolism" 8 "Nuclear membrane, Endoplasmic reticulum" "HPA027262: AB_1852717, HPA078737: " "unprognostic (1.01e-1)" "unprognostic (2.70e-3)" "unprognostic (3.72e-2)" "unprognostic (1.29e-2)" "unprognostic (8.23e-2)" "unprognostic (2.03e-2)" "unprognostic (7.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.34e-1)" "unprognostic (4.05e-2)" "unprognostic (8.17e-3)" "unprognostic (1.11e-1)" "unprognostic (2.63e-2)" "unprognostic (1.56e-1)" "unprognostic (7.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.85e-1)" CERS4 "FLJ12089, LASS4, Trh1" ENSG00000090661 "Ceramide synthase 4" Q9HA82 19 8206736-8262421 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Muller glia cells: 122.6;Suprabasal keratinocytes: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033734, HPA054729" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 17: Breast glandular cells - Lactation" 40 "Nucleoplasm, Vesicles" "CAB033734: AB_2132977, HPA054729: " "unprognostic (5.96e-2)" "prognostic favorable (2.71e-4)" "unprognostic (2.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.30e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.74e-1)" "prognostic favorable (3.45e-5)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.77e-1)" "prognostic favorable (9.63e-5)" "unprognostic (6.08e-3)" "unprognostic (2.69e-2)" "unprognostic (2.91e-2)" "unprognostic (8.08e-3)" CFTR "ABC35, ABCC7, CF, CFTR/MRP, dJ760C5.1, MRP7, TNR-CFTR" ENSG00000001626 "CF transmembrane conductance regulator" P13569 7 117287120-117715971 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Isomerase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 48.4;intestine: 43.6;pancreas: 192.0" "Group enriched" "Detected in many" 4 "Ductal cells: 590.0;Late spermatids: 149.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.9;pancreatic cancer: 28.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 24.2;Gastric cancer: 9.6" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB001951, HPA021939, HPA079652" Enhanced NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Non-specific - Mixed function" 94 "CAB001951: , HPA021939: AB_1846578, HPA079652: " "unprognostic (6.38e-3)" "unprognostic (9.55e-2)" "unprognostic (1.77e-2)" "unprognostic (1.44e-2)" "unprognostic (8.74e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (9.44e-4)" "unprognostic (3.20e-3)" "unprognostic (1.13e-1)" "unprognostic (8.89e-2)" "unprognostic (1.55e-2)" "unprognostic (2.14e-2)" "unprognostic (4.78e-3)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (9.08e-2)" "unprognostic (6.64e-2)" CLCN3 "ClC-3, CLC3" ENSG00000109572 "Chloride voltage-gated channel 3" P51790 4 169612633-169723673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044723 Approved Supported Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Retina & Testis - Cilium" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 57: Platelets - Hemostasis" Vesicles "HPA044723: AB_10959733" "unprognostic (1.92e-1)" "unprognostic (3.92e-2)" "unprognostic (1.95e-3)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.25e-1)" "unprognostic (3.32e-1)" "unprognostic (1.79e-1)" "unprognostic (5.40e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.49e-2)" "unprognostic (2.49e-1)" "unprognostic (1.45e-1)" "unprognostic (6.38e-3)" CLN3 "BTN1, BTS, JNCL" ENSG00000188603 "CLN3 lysosomal/endosomal transmembrane protein, battenin" Q13286 16 28474111-28495575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063280 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: T-cells - T-cell receptor" 3 "HPA063280: AB_2684975" "unprognostic (2.38e-3)" "unprognostic (2.41e-2)" "unprognostic (7.06e-2)" "unprognostic (8.83e-2)" "unprognostic (1.04e-1)" "unprognostic (1.68e-1)" "unprognostic (2.36e-2)" "unprognostic (1.69e-2)" "unprognostic (6.38e-3)" "unprognostic (8.16e-2)" "unprognostic (6.27e-2)" "unprognostic (5.26e-1)" "unprognostic (9.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.45e-2)" "unprognostic (1.62e-1)" "unprognostic (2.05e-2)" CLN8 "C8orf61, EPMR, FLJ39417, TLCD6" ENSG00000182372 "CLN8 transmembrane ER and ERGIC protein" Q9UBY8 8 1755778-1801711 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 352.7;Langerhans cells: 160.1;Syncytiotrophoblasts: 140.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 76.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 76.7" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 28: Dendritic cells - Antigen presentation" "unprognostic (5.86e-2)" "unprognostic (1.95e-2)" "unprognostic (6.40e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (4.05e-3)" "unprognostic (1.21e-1)" "unprognostic (3.45e-1)" "unprognostic (3.03e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-3)" "unprognostic (1.83e-1)" "prognostic favorable (4.36e-8)" "unprognostic (1.36e-1)" "unprognostic (1.70e-1)" "unprognostic (6.24e-2)" "unprognostic (8.38e-2)" CLPTM1 ENSG00000104853 "CLPTM1 regulator of GABA type A receptor forward trafficking" O96005 19 44954585-44993341 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068767 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 4: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 1 "Endoplasmic reticulum" "HPA068767: " "unprognostic (1.40e-1)" "unprognostic (1.32e-1)" "unprognostic (4.07e-1)" "unprognostic (2.19e-1)" "unprognostic (1.81e-1)" "unprognostic (3.25e-1)" "unprognostic (1.94e-1)" "unprognostic (5.93e-2)" "unprognostic (6.60e-3)" "unprognostic (2.67e-2)" "unprognostic (1.46e-3)" "unprognostic (2.62e-1)" "unprognostic (1.02e-2)" "unprognostic (3.30e-1)" "unprognostic (2.56e-1)" "unprognostic (7.46e-2)" "unprognostic (1.59e-1)" CLPTM1L "CRR9, FLJ14400" ENSG00000049656 "CLPTM1 like" Q96KA5 5 1317752-1345099 "Predicted membrane proteins, Transporters" "Apoptosis, Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 246.9;Plasma cells: 206.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014791 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 29: Non-specific - Unknown function" "Cluster 61: Plasma cells - Immunoglobulins & histones" 1 "Endoplasmic reticulum" "HPA014791: AB_1847250" "unprognostic (2.92e-2)" "unprognostic (1.34e-1)" "unprognostic (9.53e-2)" "unprognostic (8.43e-2)" "unprognostic (5.16e-3)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (5.47e-3)" "unprognostic (9.14e-3)" "unprognostic (1.06e-1)" "unprognostic (5.77e-3)" "unprognostic (8.57e-2)" "unprognostic (4.92e-2)" "unprognostic (4.54e-2)" "unprognostic (4.17e-2)" CTNS "CTNS-LSB, PQLC4, SLC66A4" ENSG00000040531 "Cystinosin, lysosomal cystine transporter" O60931 17 3636459-3663103 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Protein transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 30.9;Late spermatids: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.3;granulocytes: 28.2;monocytes: 10.5" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074687 Supported Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 46: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 50: Lymphoma - Unknown function" "Cluster 58: Macrophages - Innate immune response" Vesicles "HPA074687: " "unprognostic (1.64e-1)" "unprognostic (1.70e-1)" "unprognostic (1.21e-1)" "unprognostic (8.25e-2)" "unprognostic (8.39e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.28e-2)" "unprognostic (8.02e-2)" "unprognostic (1.94e-1)" "unprognostic (6.62e-3)" "prognostic favorable (6.39e-5)" "unprognostic (8.40e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-1)" "unprognostic (5.64e-2)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" CYB561 "CYB561A1, FRRS2" ENSG00000008283 "Cytochrome b561" P49447 17 63432304-63446354 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 81.4;Prostatic glandular cells: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014753 Enhanced NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 49 "HPA014753: AB_1847364" "prognostic unfavorable (8.89e-5)" "unprognostic (2.90e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-5)" "unprognostic (1.81e-3)" "unprognostic (3.82e-1)" "unprognostic (1.37e-2)" "unprognostic (8.47e-2)" "unprognostic (2.07e-1)" "unprognostic (3.91e-2)" "unprognostic (8.97e-2)" "unprognostic (6.38e-2)" "unprognostic (8.09e-3)" "unprognostic (1.16e-3)" "unprognostic (8.17e-2)" "unprognostic (1.50e-2)" "unprognostic (2.89e-1)" CYB561A3 CYBASC3 ENSG00000162144 "Cytochrome b561 family member A3" Q8NBI2 11 61348754-61362283 "Enzymes, Predicted membrane proteins" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 243.6" "Group enriched" "Detected in many" 4 "dendritic cells: 285.0;Melanocytes: 536.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "memory B-cell: 315.4;naive B-cell: 387.5;plasmacytoid DC: 843.5" "Group enriched" "Detected in all" 9 "B-cells: 387.5;dendritic cells: 843.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045674, HPA052548" Approved Approved Nucleoli,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 47: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 21 Vesicles Nucleoli "HPA045674: , HPA052548: AB_2681866" "unprognostic (2.61e-1)" "unprognostic (8.78e-2)" "unprognostic (4.16e-1)" "unprognostic (3.62e-2)" "unprognostic (1.37e-1)" "unprognostic (9.41e-3)" "unprognostic (7.41e-3)" "unprognostic (2.48e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" "unprognostic (2.22e-2)" "unprognostic (3.73e-1)" "unprognostic (2.53e-1)" "unprognostic (2.83e-1)" "unprognostic (3.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.80e-3)" CYB561D1 "FLJ39035, FLJ44753" ENSG00000174151 "Cytochrome b561 family member D1" Q8N8Q1 1 109494052-109502932 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 15.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027028 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Skin - Cornification" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 19: NK-cells - Adaptive immune response" 3 "HPA027028: AB_1847365" "unprognostic (2.15e-2)" "unprognostic (3.49e-1)" "unprognostic (1.04e-2)" "unprognostic (1.98e-1)" "unprognostic (2.27e-1)" "prognostic favorable (4.68e-4)" "unprognostic (4.53e-4)" "unprognostic (1.32e-1)" "unprognostic (3.45e-1)" "unprognostic (5.29e-2)" "prognostic favorable (5.16e-6)" "unprognostic (4.30e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.20e-3)" "unprognostic (2.75e-1)" "unprognostic (4.95e-3)" "unprognostic (5.82e-2)" CYB561D2 "101F6, TSP10" ENSG00000114395 "Cytochrome b561 family member D2" O14569 3 50350845-50358460 "Enzymes, Predicted membrane proteins" "Electron transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071862 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 17: Breast glandular cells - Lactation" 16 "HPA071862: " "unprognostic (4.89e-2)" "unprognostic (3.25e-1)" "unprognostic (2.02e-1)" "unprognostic (6.98e-2)" "unprognostic (5.15e-2)" "unprognostic (2.72e-2)" "unprognostic (2.28e-3)" "unprognostic (2.47e-2)" "unprognostic (1.76e-1)" "unprognostic (5.41e-2)" "prognostic favorable (1.86e-4)" "unprognostic (3.26e-1)" "prognostic favorable (6.16e-5)" "unprognostic (4.33e-2)" "unprognostic (1.89e-1)" "unprognostic (2.18e-1)" "unprognostic (7.57e-2)" CYBB "CGD, GP91-PHOX, NOX2" ENSG00000165168 "Cytochrome b-245 beta chain" P04839 X 37780018-37813461 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 157.3;lymphoid tissue: 145.7" "Cell type enhanced" "Detected in many" "dendritic cells: 329.2;Hofbauer cells: 223.4;Kupffer cells: 356.9;Macrophages: 445.8;monocytes: 644.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 318.5" "Group enriched" "Detected in many" 5 "dendritic cells: 80.2;granulocytes: 106.4;monocytes: 318.5" "Group enriched" "Detected in some" 4 "Leukemia: 15.8;lymphoma: 29.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051227 Enhanced NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Monocytes - Innate immune response" 1 "HPA051227: AB_2681395" "unprognostic (5.83e-2)" "unprognostic (1.77e-2)" "unprognostic (2.15e-3)" "unprognostic (1.48e-2)" "unprognostic (1.27e-1)" "unprognostic (5.65e-2)" "unprognostic (2.29e-2)" "unprognostic (4.45e-2)" "unprognostic (9.14e-2)" "unprognostic (2.32e-2)" "unprognostic (5.73e-2)" "unprognostic (5.18e-2)" "unprognostic (5.92e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (9.72e-2)" CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 229.2;Leydig cells: 193.7;Peritubular cells: 215.1;Proximal enterocytes: 691.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.8;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.8" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 22: Proximal enterocytes - Digestion" 19 "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" DAGLA "C11orf11, DAGLALPHA, KIAA0659, NSDDR" ENSG00000134780 "Diacylglycerol lipase alpha" Q9Y4D2 11 61680391-61747001 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Excitatory neurons: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062497, CAB078793" Approved Supported NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 16: Intestinal goblet cells - Mucin production" 9 "CAB078793: , HPA062497: AB_2684784" "unprognostic (2.53e-3)" "unprognostic (1.85e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.13e-7)" "unprognostic (1.23e-1)" "unprognostic (1.70e-1)" "unprognostic (1.14e-4)" "unprognostic (2.22e-2)" "unprognostic (2.29e-3)" "unprognostic (3.99e-3)" "unprognostic (1.55e-1)" "unprognostic (1.09e-1)" "unprognostic (1.11e-3)" "unprognostic (1.53e-1)" "unprognostic (1.52e-1)" "unprognostic (1.08e-1)" "unprognostic (1.14e-2)" DCST1 FLJ32785 ENSG00000163357 "DC-STAMP domain containing 1" Q5T197 1 155033824-155050930 "Enzymes, Predicted membrane proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 2.5;skin 1: 3.0;testis: 6.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 8.5;Early spermatids: 39.5;Late spermatids: 17.6;Rod photoreceptor cells: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA060314 Uncertain NA NA "Cluster 21: Testis - Unknown function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 66: Photoreceptor cells - Visual perception" "HPA060314: AB_2684250" "unprognostic (1.44e-1)" "unprognostic (7.66e-2)" "unprognostic (3.77e-2)" "unprognostic (1.05e-4)" "unprognostic (3.58e-2)" "unprognostic (8.75e-4)" "unprognostic (1.46e-2)" "unprognostic (2.66e-1)" "unprognostic (6.01e-3)" "unprognostic (2.22e-1)" "unprognostic (6.62e-2)" "unprognostic (1.89e-2)" "unprognostic (8.33e-15)" "unprognostic (7.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.38e-1)" "unprognostic (1.23e-1)" DERL2 "CGI-101, derlin-2, F-LAN-1, F-LANa, FLANa" ENSG00000072849 "Derlin 2" Q9GZP9 17 5471254-5486811 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 281.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037287, HPA048957, HPA056551" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 77: Plasma cells - Protein processing" 8 "Endoplasmic reticulum" "CAB037287: AB_1078641, HPA048957: AB_2680570, HPA056551: AB_2683171" "unprognostic (2.54e-1)" "unprognostic (5.30e-2)" "unprognostic (5.83e-2)" "prognostic favorable (7.26e-4)" "unprognostic (1.51e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.63e-1)" "unprognostic (2.17e-1)" "unprognostic (1.12e-3)" "unprognostic (1.73e-3)" "unprognostic (5.23e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (3.73e-1)" "unprognostic (2.91e-2)" DNAJC22 "FLJ13236, wus" ENSG00000178401 "DnaJ heat shock protein family (Hsp40) member C22" Q8N4W6 12 49346888-49357546 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 23.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 42.0;Distal enterocytes: 34.4;Enteroendocrine cells: 32.6;Hepatocytes: 38.1;Intestinal goblet cells: 31.4;Mesothelial cells: 27.6;Paneth cells: 33.6;Proximal enterocytes: 55.9;Undifferentiated cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Region enhanced" "Detected in single" "midbrain: 1.2" "Low region specificity" "Detected in all" HPA039953 Approved Vesicles NA NA "Cluster 83: Liver - Metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" Vesicles "HPA039953: AB_2676770" "unprognostic (5.23e-2)" "unprognostic (1.24e-1)" "unprognostic (9.01e-2)" "prognostic favorable (4.56e-5)" "unprognostic (4.77e-3)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (4.05e-2)" "prognostic unfavorable (7.54e-4)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (3.18e-2)" "unprognostic (9.35e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-2)" DRAM1 "DRAM, FLJ11259" ENSG00000136048 "DNA damage regulated autophagy modulator 1" Q8N682 12 101877580-102012130 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 91.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 187.5;Early spermatids: 142.4;Late spermatids: 98.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 57: Lung - Lung function" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Alveolar cells - Lung function" 6 "unprognostic (8.82e-2)" "unprognostic (1.80e-1)" "unprognostic (7.19e-2)" "prognostic favorable (6.52e-8)" "unprognostic (1.15e-2)" "unprognostic (2.35e-3)" "unprognostic (1.29e-3)" "unprognostic (1.23e-2)" "unprognostic (1.47e-1)" "unprognostic (2.35e-1)" "unprognostic (6.17e-3)" "unprognostic (5.02e-2)" "prognostic unfavorable (3.91e-4)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (3.58e-2)" "unprognostic (2.07e-2)" DRAM2 "MGC54289, PRO180, RP5-1180E21.1, TMEM77, WWFQ154" ENSG00000156171 "DNA damage regulated autophagy modulator 2" Q6UX65 1 111117163-111140203 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 191.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018036, HPA061701" Supported Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 25: Non-specific - Ribosome" "Cluster 73: B-cells - B-cell function" "Golgi apparatus, Vesicles" "HPA018036: AB_1858134, HPA061701: AB_2684590" "unprognostic (9.38e-3)" "unprognostic (1.58e-2)" "unprognostic (2.16e-3)" "unprognostic (5.22e-2)" "unprognostic (1.12e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.57e-3)" "prognostic unfavorable (6.43e-4)" "unprognostic (2.69e-1)" "unprognostic (4.37e-3)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (1.77e-3)" EI24 "EPG4, PIG8, TP53I8" ENSG00000149547 "EI24 autophagy associated transmembrane protein" O14681 11 125569280-125584684 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 447.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 526.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047165, HPA051029" Approved Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 43: Hepatocytes - Metabolism" 8 "Endoplasmic reticulum, Cytosol" "Golgi apparatus" "HPA047165: AB_2679965, HPA051029: AB_2681317" "unprognostic (2.04e-3)" "unprognostic (2.69e-2)" "unprognostic (1.25e-2)" "unprognostic (3.43e-2)" "unprognostic (1.68e-1)" "unprognostic (2.78e-2)" "unprognostic (5.02e-2)" "unprognostic (6.38e-2)" "unprognostic (6.74e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (9.28e-4)" "unprognostic (3.50e-2)" "unprognostic (1.35e-1)" "unprognostic (4.58e-2)" "unprognostic (8.35e-2)" "unprognostic (2.07e-1)" "unprognostic (3.01e-1)" ELOVL1 Ssc1 ENSG00000066322 "ELOVL fatty acid elongase 1" Q9BW60 1 43363398-43368074 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 344.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033426, HPA056557" Enhanced Supported "Endoplasmic reticulum" NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 37: Non-specific - mRNA processing" "Cluster 59: Suprabasal keratinocytes - Cornification" "Endoplasmic reticulum" "CAB033426: AB_2099896, HPA056557: AB_2683173" "unprognostic (5.23e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (8.00e-2)" "unprognostic (8.45e-2)" "unprognostic (7.60e-2)" "unprognostic (7.40e-2)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.74e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "prognostic unfavorable (8.51e-4)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (1.41e-2)" "unprognostic (1.28e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" ENSG00000258881 ENSG00000258881 "Novel protein" 2 70939318-70995336 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "retina: 1.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.8;Cone photoreceptor cells: 3.4;Horizontal cells: 4.4;Lymphatic endothelial cells: 2.8;Rod photoreceptor cells: 17.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 2.9" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 48: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 66: Photoreceptor cells - Visual perception" "unprognostic (1.86e-1)" "unprognostic (2.94e-1)" "unprognostic (7.99e-4)" "unprognostic (1.36e-1)" "unprognostic (9.49e-2)" "unprognostic (1.78e-3)" "unprognostic (2.35e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-1)" "unprognostic (1.95e-2)" "unprognostic (1.52e-1)" "unprognostic (2.93e-1)" "unprognostic (2.53e-9)" "unprognostic (6.54e-2)" "unprognostic (7.86e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" ENSG00000283765 ENSG00000283765 "Novel protein" 3 183815568-183884889 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;skeletal muscle: 5.3" "Group enriched" "Detected in some" 37 "Astrocytes: 17.0;Excitatory neurons: 22.6;Inhibitory neurons: 23.1;Microglial cells: 32.2;Oligodendrocyte precursor cells: 16.0;Oligodendrocytes: 26.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" HPA019545 Uncertain Approved Mitochondria NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 6: Non-specific - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Neurons - Neuronal signaling" Mitochondria "HPA019545: AB_1855796" ENSG00000286235 ENSG00000286235 "Novel protein" 20 5950949-6039856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "HPA045141, HPA066433" Approved Nucleoplasm,Cytosol NA NA "Cluster 15: Kidney cancer - Membrane components" Nucleoplasm Cytosol "HPA045141: AB_2679230, HPA066433: " ENSG00000289258 ENSG00000289258 "Novel protein" 10 86654518-86700020 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039147, HPA048955" Uncertain Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 33: Neurons - Mixed function" "Focal adhesion sites" "Nucleoplasm, Cytosol" "HPA039147: AB_10673304, HPA048955: AB_2680568" FADS3 "CYB5RP, LLCDL3" ENSG00000221968 "Fatty acid desaturase 3" Q9Y5Q0 11 61873519-61892051 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 142.2;Alveolar cells type 1: 209.8;Extravillous trophoblasts: 150.6;Rod photoreceptor cells: 123.3;Schwann cells: 111.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.7;naive B-cell: 8.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045224 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 30: Heart muscle - Heart development" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Nucleoli fibrillar center" "HPA045224: AB_10967570" "unprognostic (4.69e-3)" "unprognostic (1.31e-2)" "unprognostic (5.55e-3)" "unprognostic (1.20e-1)" "unprognostic (2.91e-2)" "prognostic unfavorable (9.54e-5)" "unprognostic (1.76e-3)" "unprognostic (3.46e-1)" "unprognostic (6.45e-2)" "unprognostic (1.49e-1)" "unprognostic (1.28e-3)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.50e-9)" "unprognostic (1.14e-1)" "unprognostic (3.92e-2)" "unprognostic (1.53e-1)" "unprognostic (2.37e-1)" FITM1 FIT1 ENSG00000139914 "Fat storage inducing transmembrane protein 1" A5D6W6 14 24130659-24132849 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "heart muscle: 165.7;skeletal muscle: 216.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 273.2;Skeletal myocytes: 272.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019842 Uncertain NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA019842: AB_1853025" "unprognostic (1.81e-2)" "unprognostic (4.29e-7)" "unprognostic (2.77e-1)" "unprognostic (2.02e-3)" "unprognostic (2.24e-2)" "unprognostic (6.68e-2)" "prognostic favorable (1.00e-3)" "unprognostic (1.20e-4)" "unprognostic (4.57e-1)" "unprognostic (2.12e-2)" "unprognostic (2.84e-2)" "unprognostic (3.68e-2)" "unprognostic (2.47e-1)" "unprognostic (2.86e-2)" "unprognostic (5.62e-1)" "unprognostic (1.96e-1)" "unprognostic (2.12e-3)" FLVCR2 "C14orf58, CCT, FLJ20371, MFSD7C, SLC49A2" ENSG00000119686 "FLVCR heme transporter 2" Q9UPI3 14 75578620-75663214 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 29.3" "Cell type enhanced" "Detected in many" "Early spermatids: 73.3;Kupffer cells: 41.1;Late spermatids: 139.4;Microglial cells: 39.4;Proximal enterocytes: 41.4;Syncytiotrophoblasts: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 14.1;intermediate monocyte: 14.6;myeloid DC: 7.6;non-classical monocyte: 11.9" "Group enriched" "Detected in many" 7 "dendritic cells: 7.6;monocytes: 14.6" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037984 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA037984: AB_10672733" "unprognostic (2.42e-1)" "unprognostic (4.85e-2)" "unprognostic (4.19e-2)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "unprognostic (4.44e-2)" "unprognostic (8.72e-2)" "unprognostic (2.78e-1)" "unprognostic (3.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.22e-1)" "unprognostic (4.80e-2)" "prognostic favorable (2.53e-5)" "unprognostic (6.69e-2)" "unprognostic (9.94e-2)" "unprognostic (9.38e-2)" "unprognostic (1.16e-1)" FRRS1 "SDFR2, SDR2" ENSG00000156869 "Ferric chelate reductase 1" Q6ZNA5 1 99703970-99766635 "Predicted membrane proteins" "Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 27.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.5;Hepatocytes: 45.5;Syncytiotrophoblasts: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "eosinophil: 12.4" "Lineage enriched" "Detected in many" 9 "granulocytes: 12.4" "Cancer enriched" "Detected in all" 8 "Gallbladder cancer: 81.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA017883 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA017883: AB_2294223" "unprognostic (3.97e-2)" "unprognostic (8.02e-2)" "unprognostic (1.25e-1)" "unprognostic (2.07e-2)" "unprognostic (6.63e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (8.54e-3)" "unprognostic (7.00e-2)" "unprognostic (2.64e-1)" "unprognostic (8.25e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (2.65e-2)" "unprognostic (1.83e-2)" "unprognostic (3.56e-2)" "unprognostic (3.54e-2)" G6PC3 UGRP ENSG00000141349 "Glucose-6-phosphatase catalytic subunit 3" Q9BUM1 17 44070620-44082151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067052 Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA067052: AB_2685771" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" "unprognostic (3.61e-1)" "prognostic favorable (1.11e-4)" "unprognostic (1.88e-3)" "unprognostic (3.16e-1)" "prognostic unfavorable (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (2.43e-1)" "unprognostic (1.15e-2)" "unprognostic (2.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.87e-3)" "unprognostic (4.53e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.49e-2)" GCGR GGR ENSG00000215644 "Glucagon receptor" P47871 17 81804132-81814008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "kidney: 48.6;liver: 165.5" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 56.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 10.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071228 Uncertain "Golgi apparatus" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Hepatocytes - Metabolism" "Golgi apparatus" "HPA071228: AB_2686368" "unprognostic (3.28e-4)" "unprognostic (9.30e-2)" "unprognostic (2.20e-1)" "unprognostic (1.53e-4)" "unprognostic (1.11e-1)" "unprognostic (2.30e-3)" "unprognostic (4.38e-2)" "unprognostic (1.79e-3)" "unprognostic (2.18e-1)" "unprognostic (2.77e-1)" "unprognostic (3.09e-1)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (5.99e-3)" "unprognostic (1.71e-1)" "unprognostic (1.17e-3)" "unprognostic (8.36e-3)" GDPD2 "FLJ20207, GDE3, OBDPF" ENSG00000130055 "Glycerophosphodiester phosphodiesterase domain containing 2" Q9HCC8 X 70423031-70433390 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 14.7;intestine: 20.2;lymphoid tissue: 57.7;skin 1: 46.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 38.3;Distal enterocytes: 31.4;Muller glia cells: 28.0;Proximal enterocytes: 94.9" "Cancer enhanced" "Detected in many" "glioma: 10.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 6.2" "Colon - Colon enterocytes, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 13: Skin - Cornification" "Cluster 46: Brainstem - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" "unprognostic (1.53e-3)" "unprognostic (5.79e-2)" "unprognostic (5.37e-2)" "unprognostic (5.00e-7)" "unprognostic (3.15e-3)" "unprognostic (3.65e-2)" "unprognostic (2.86e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-1)" "unprognostic (8.40e-2)" "unprognostic (8.45e-2)" "unprognostic (1.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.41e-2)" "unprognostic (5.52e-2)" "unprognostic (2.22e-1)" "unprognostic (8.91e-2)" GDPD5 "GDE2, PP1665" ENSG00000158555 "Glycerophosphodiester phosphodiesterase domain containing 5" Q8WTR4 11 75434640-75525941 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Neurogenesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 113.8;retina: 80.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 54.8;Cone photoreceptor cells: 112.1;Early spermatids: 39.8;Late spermatids: 167.8;Rod photoreceptor cells: 83.8;Syncytiotrophoblasts: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.7" "Group enriched" "Detected in many" 6 "granulocytes: 7.7;T-cells: 2.0" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Liver - Vascular Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065257, HPA066762, HPA069281" Uncertain Approved "Golgi apparatus" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 63: Late spermatids - Spermatogenesis" 2 "Golgi apparatus" "HPA065257: AB_2685447, HPA066762: AB_2685715, HPA069281: AB_2686107" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (9.97e-3)" "unprognostic (4.05e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-1)" "unprognostic (3.07e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.59e-9)" "unprognostic (8.64e-2)" "unprognostic (1.30e-1)" "unprognostic (4.39e-2)" "unprognostic (1.65e-1)" GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544720-85561532 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 104.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 142.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 83: Liver - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 62: Hepatocytes - Metabolism" "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" GHITM "DERP2, HSPC282, My021, PTD010, TMBIM5" ENSG00000165678 "Growth hormone inducible transmembrane protein" Q9H3K2 10 84139482-84154841 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1011.6;Early spermatids: 958.2;Late spermatids: 2582.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016464, HPA061664" Approved Supported Mitochondria NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 23: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 36: Late spermatids - Unknown function" 7 Mitochondria "HPA016464: AB_1849656, HPA061664: AB_2684579" "unprognostic (6.26e-3)" "unprognostic (1.85e-1)" "unprognostic (2.75e-2)" "unprognostic (1.51e-1)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (5.71e-2)" "unprognostic (4.56e-2)" "unprognostic (1.76e-1)" "unprognostic (1.28e-1)" "unprognostic (8.14e-2)" "unprognostic (5.71e-2)" "prognostic favorable (2.32e-10)" "unprognostic (2.46e-2)" "unprognostic (2.09e-1)" "unprognostic (3.56e-2)" "unprognostic (1.25e-1)" GHSR ENSG00000121853 "Growth hormone secretagogue receptor" Q92847 3 172443291-172448456 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "pituitary gland: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "hypothalamus: 32.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 3.3" "Low region specificity" "Detected in all" NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.27e-1)" "unprognostic (3.31e-2)" GPAA1 "GAA1, hGAA1" ENSG00000197858 "Glycosylphosphatidylinositol anchor attachment 1" O43292 8 144082337-144093149 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077224 Approved Approved "Endoplasmic reticulum,Centrosome,Mitochondria,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 3 "Endoplasmic reticulum, Cytosol" "Centrosome, Mitochondria" "HPA077224: " "unprognostic (2.53e-3)" "unprognostic (1.39e-1)" "unprognostic (3.06e-2)" "unprognostic (2.57e-2)" "unprognostic (2.49e-2)" "unprognostic (4.05e-2)" "unprognostic (1.73e-3)" "unprognostic (2.64e-1)" "unprognostic (8.92e-2)" "unprognostic (1.67e-2)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (3.89e-1)" "unprognostic (1.27e-1)" "unprognostic (2.73e-2)" GPR137 "C11orf4, GPR137A, TM7SF1L1" ENSG00000173264 "G protein-coupled receptor 137" Q96N19 11 64270062-64289500 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 198.2" "Cell type enhanced" "Detected in all" "Early spermatids: 178.8;Late spermatids: 539.9;Spermatocytes: 144.1;Syncytiotrophoblasts: 117.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062871 Uncertain Approved "Nucleoplasm,Nucleoli,Actin filaments" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" "Nucleoplasm, Nucleoli" "Actin filaments" "HPA062871: AB_2684889" "unprognostic (2.25e-1)" "unprognostic (4.21e-2)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.29e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.34e-4)" "unprognostic (5.68e-2)" "unprognostic (1.83e-2)" "unprognostic (7.61e-3)" "prognostic favorable (6.18e-4)" "unprognostic (4.95e-2)" "unprognostic (8.66e-3)" "unprognostic (3.67e-3)" "unprognostic (2.28e-1)" "unprognostic (2.13e-1)" "unprognostic (5.41e-1)" GPR137C "DKFZp762F0713, TM7SF1L2" ENSG00000180998 "G protein-coupled receptor 137C" Q8N3F9 14 52552836-52637713 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 29.9;epididymis: 7.6;retina: 16.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 82.5;Inhibitory neurons: 119.8;Oligodendrocyte precursor cells: 95.3;Oligodendrocytes: 127.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 15 "NK-cells: 1.5;T-cells: 1.4" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003640, HPA030763" Uncertain Approved Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" Vesicles "HPA003640: AB_2667025, HPA030763: AB_10602352" "unprognostic (1.39e-1)" "unprognostic (1.45e-1)" "unprognostic (1.23e-1)" "unprognostic (6.84e-2)" "unprognostic (8.50e-3)" "unprognostic (7.34e-3)" "unprognostic (5.95e-3)" "unprognostic (2.32e-2)" "unprognostic (4.41e-2)" "unprognostic (8.42e-4)" "unprognostic (2.20e-2)" "unprognostic (1.04e-1)" "unprognostic (7.88e-2)" "unprognostic (4.08e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (2.60e-1)" GPR149 "IEDA, PGR10, R35" ENSG00000174948 "G protein-coupled receptor 149" Q86SP6 3 154334943-154430190 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;seminal vesicle: 1.4" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 46.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "prostate cancer: 1.0" "Region enhanced" "Detected in many" "basal ganglia: 15.0" "Low region specificity" "Detected in many" HPA018020 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA018020: AB_1849334" GPR153 PGR1 ENSG00000158292 "G protein-coupled receptor 153" Q6NV75 1 6247353-6261098 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.3;Horizontal cells: 46.6;Intestinal goblet cells: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 36.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007159 Approved NA NA "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA007159: AB_1849268" "unprognostic (1.02e-2)" "unprognostic (2.40e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (5.74e-3)" "unprognostic (3.33e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (8.54e-2)" "unprognostic (1.02e-2)" "unprognostic (1.31e-1)" "unprognostic (1.51e-2)" "unprognostic (1.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.93e-1)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" GPR26 ENSG00000154478 "G protein-coupled receptor 26" Q8NDV2 10 123666355-123697399 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "brain: 2.8" "Group enriched" "Detected in some" 6 "Excitatory neurons: 11.0;Horizontal cells: 8.2" "Cancer enriched" "Detected in single" 13 "breast cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebral cortex: 81.5" HPA062736 Enhanced NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "HPA062736: AB_2684855" "unprognostic (4.15e-2)" "unprognostic (5.75e-2)" "unprognostic (3.42e-1)" "unprognostic (2.12e-1)" "unprognostic (9.09e-2)" "unprognostic (9.98e-2)" "unprognostic (2.12e-2)" "unprognostic (1.16e-2)" "unprognostic (1.12e-1)" GPR31 "12-HETER, HETER1" ENSG00000120436 "G protein-coupled receptor 31" O00270 6 167155247-167157980 "G-protein coupled receptors, Predicted membrane proteins" "Lipid metabolism" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in single" 5 "Schwann cells: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014014, HPA027108" Uncertain NA NA "Cluster 70: Lymphoid tissue - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA014014: AB_1849292, HPA027108: AB_10601474" "unprognostic (9.92e-2)" "unprognostic (1.52e-1)" "unprognostic (1.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.42e-3)" "unprognostic (2.20e-3)" "unprognostic (5.95e-3)" "unprognostic (4.03e-2)" "unprognostic (3.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (8.10e-4)" "unprognostic (2.45e-1)" "unprognostic (6.01e-2)" GPR39 ENSG00000183840 "G protein-coupled receptor 39" O43194 2 132416805-132646582 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.4;Astrocytes: 11.5;Early spermatids: 19.7;Late spermatids: 19.6;Oligodendrocyte precursor cells: 17.5;Oocytes: 22.1;Spermatocytes: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA022111 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "HPA022111: AB_1849298" "unprognostic (4.06e-2)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (1.50e-2)" "unprognostic (5.19e-2)" "unprognostic (1.85e-1)" "unprognostic (8.54e-3)" "unprognostic (3.81e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (2.28e-1)" "unprognostic (1.64e-1)" "unprognostic (3.72e-1)" "unprognostic (4.69e-2)" "unprognostic (1.25e-1)" "unprognostic (6.58e-3)" GPR55 ENSG00000135898 "G protein-coupled receptor 55" Q9Y2T6 2 230907318-230961066 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5;lymphoid tissue: 4.3;testis: 4.5" "Cell type enhanced" "Detected in some" "B-cells: 1.8;dendritic cells: 2.2;Excitatory neurons: 2.2;Intestinal goblet cells: 2.5;Langerhans cells: 4.1;Plasma cells: 2.1;T-cells: 6.0" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 4 "basal ganglia: 9.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.9;lymphoma: 4.7" "Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 33: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 7: T-cells - T-cell receptor" "unprognostic (9.88e-4)" "unprognostic (2.60e-2)" "unprognostic (2.27e-1)" "unprognostic (4.24e-3)" "unprognostic (5.93e-2)" "unprognostic (1.12e-4)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (4.37e-2)" "unprognostic (3.18e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-2)" "unprognostic (4.26e-1)" GPR78 ENSG00000155269 "G protein-coupled receptor 78" Q96P69 4 8558725-8619761 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 1.4;placenta: 2.9" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 20.6" "Cancer enhanced" "Detected in single" "urothelial cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bladder cancer: 5.1;testis cancer: 2.6" HPA013209 Uncertain NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 51: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA013209: AB_10601657" "unprognostic (6.41e-2)" "unprognostic (1.77e-2)" "unprognostic (1.17e-2)" "unprognostic (2.51e-1)" "unprognostic (1.81e-2)" "unprognostic (3.70e-2)" "unprognostic (3.82e-4)" "unprognostic (6.46e-3)" "unprognostic (1.20e-1)" "unprognostic (3.80e-2)" "unprognostic (2.29e-1)" "unprognostic (4.88e-15)" "unprognostic (5.55e-3)" "unprognostic (3.93e-2)" "unprognostic (9.90e-3)" "unprognostic (8.15e-2)" GPR83 GPR72 ENSG00000123901 "G protein-coupled receptor 83" Q9NYM4 11 94377316-94401419 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 15.4" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.1;Early spermatids: 1.0;Excitatory neurons: 2.5;Inhibitory neurons: 4.2" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in many" "basal ganglia: 67.5" "Low region specificity" "Detected in many" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 69: Neurons - Neuronal signaling" "unprognostic (6.74e-2)" "unprognostic (7.78e-3)" "unprognostic (8.58e-2)" "unprognostic (2.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.88e-1)" "unprognostic (6.36e-3)" "unprognostic (6.89e-2)" "unprognostic (6.03e-2)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "unprognostic (6.17e-2)" "unprognostic (1.47e-12)" "unprognostic (3.16e-1)" "unprognostic (1.64e-1)" "unprognostic (1.33e-2)" "unprognostic (8.28e-3)" GRINA "HNRGW, LFG1, NMDARA1, TMBIM3" ENSG00000178719 "Glutamate ionotropic receptor NMDA type subunit associated protein 1" Q7Z429 8 143990056-143993415 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 428.6;monocytes: 329.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036980, HPA036981" Approved Approved "Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 25: Non-specific - Unknown function" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 14: Langerhans cells - Innate immune response" 6 "Nucleoli fibrillar center" Cytosol "HPA036980: AB_10696791, HPA036981: AB_10962980" "unprognostic (2.73e-3)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (7.01e-3)" "unprognostic (3.72e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-2)" "unprognostic (2.32e-1)" "unprognostic (6.70e-2)" "unprognostic (8.19e-2)" "unprognostic (3.13e-3)" "unprognostic (1.01e-3)" "unprognostic (1.55e-1)" "unprognostic (9.43e-2)" "unprognostic (6.75e-2)" "unprognostic (5.72e-2)" GRM7 "GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87" ENSG00000196277 "Glutamate metabotropic receptor 7" Q14831 3 6770001-7741533 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cardiomyopathy, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;parathyroid gland: 4.1" "Group enriched" "Detected in some" 15 "Excitatory neurons: 748.5;Inhibitory neurons: 568.5;Oligodendrocyte precursor cells: 1115.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015964 Uncertain Cytosol NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA015964: " "unprognostic (2.04e-2)" "unprognostic (7.03e-3)" "unprognostic (1.43e-1)" "unprognostic (9.37e-2)" "unprognostic (8.48e-3)" "unprognostic (2.58e-1)" "unprognostic (7.30e-2)" "unprognostic (3.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.46e-2)" "unprognostic (2.54e-1)" "unprognostic (6.84e-6)" "unprognostic (1.45e-1)" "unprognostic (2.82e-2)" "unprognostic (5.43e-2)" "unprognostic (2.59e-2)" HACD2 PTPLB ENSG00000206527 "3-hydroxyacyl-CoA dehydratase 2" Q6Y1H2 3 123490820-123585053 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB019282 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 11: Liver - Plasma proteins" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 15: Non-specific - Mixed function" 8 "CAB019282: " "unprognostic (3.04e-2)" "unprognostic (2.51e-1)" "unprognostic (6.11e-2)" "unprognostic (2.65e-3)" "unprognostic (5.36e-2)" "unprognostic (6.04e-2)" "unprognostic (1.32e-2)" "unprognostic (1.95e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (9.59e-5)" "unprognostic (6.90e-2)" "unprognostic (7.03e-3)" "unprognostic (1.48e-1)" "unprognostic (3.85e-2)" "unprognostic (1.94e-2)" "unprognostic (2.59e-2)" HACD3 "B-ind1, HSPC121, PTPLAD1" ENSG00000074696 "3-hydroxyacyl-CoA dehydratase 3" Q9P035 15 65530418-65578349 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014837, HPA060347" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 58: Non-specific - Nuclear processes" "Cluster 24: Cytotrophoblasts - Mitochondria" "Endoplasmic reticulum" "HPA014837: AB_1855914, HPA060347: AB_2684260" "unprognostic (1.51e-2)" "unprognostic (2.89e-1)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (3.52e-1)" "unprognostic (1.92e-2)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (3.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.57e-1)" "prognostic favorable (3.09e-5)" "unprognostic (3.44e-2)" "unprognostic (5.33e-2)" "unprognostic (1.10e-2)" "unprognostic (2.04e-2)" HCN2 "BCNG-2, BCNG2, HAC-1" ENSG00000099822 "Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2" Q9UL51 19 589881-617159 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Sodium transport, Transport" "Ion channel, Ligand-gated ion channel, Potassium channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 100.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 54.6;Horizontal cells: 27.7;Inhibitory neurons: 18.0;Oligodendrocytes: 57.7;Oocytes: 27.2" "Group enriched" "Detected in many" 6 "glioma: 8.7;melanoma: 5.7;renal cancer: 2.8;testis cancer: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 13.4" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 18: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 25: Bipolar cells - Visual perception" "unprognostic (8.69e-2)" "unprognostic (3.97e-3)" "unprognostic (3.31e-4)" "unprognostic (1.44e-1)" "unprognostic (2.44e-1)" "unprognostic (3.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.97e-2)" "unprognostic (1.55e-1)" "unprognostic (5.32e-2)" "unprognostic (1.19e-3)" "unprognostic (8.00e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.07e-1)" "unprognostic (1.41e-1)" "unprognostic (5.53e-4)" "unprognostic (9.72e-3)" HGSNAT "FLJ32731, HGNAT, TMEM76" ENSG00000165102 "Heparan-alpha-glucosaminide N-acetyltransferase" Q68CP4 8 43140464-43202855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mucopolysaccharidosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029578 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" "HPA029578: AB_10602423" "unprognostic (5.35e-2)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.46e-4)" "unprognostic (3.94e-3)" "unprognostic (1.10e-1)" "unprognostic (6.54e-3)" "unprognostic (5.02e-2)" "prognostic favorable (6.33e-5)" "unprognostic (2.55e-2)" "unprognostic (5.48e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "unprognostic (3.45e-2)" HM13 "dJ324O17.1, H13, IMP1, IMPAS, PSENL3, PSL3, SPP, SPPL1" ENSG00000101294 "Histocompatibility minor 13" Q8TCT9 20 31514410-31577923 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 438.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045089, HPA056062" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 77: Plasma cells - Protein processing" 4 "Endoplasmic reticulum" "HPA045089: AB_10962054, HPA056062: AB_2683022" "unprognostic (8.03e-2)" "unprognostic (2.11e-2)" "unprognostic (5.03e-2)" "unprognostic (1.59e-1)" "unprognostic (2.82e-1)" "unprognostic (5.87e-3)" "prognostic unfavorable (1.95e-5)" "unprognostic (2.66e-2)" "unprognostic (2.14e-2)" "unprognostic (2.55e-1)" "unprognostic (2.30e-1)" "unprognostic (8.10e-2)" "prognostic unfavorable (4.64e-12)" "unprognostic (3.77e-2)" "unprognostic (1.57e-1)" "unprognostic (1.85e-1)" "unprognostic (8.17e-2)" HTT "HD, IT15" ENSG00000197386 Huntingtin P42858 4 3041363-3243957 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002756, HPA026114, HPA051524" Approved Supported Nucleoplasm,Cytosol NA NA 36000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 66: Photoreceptor cells - Visual perception" 665 Nucleoplasm Cytosol "CAB002756: , HPA026114: AB_1851330, HPA051524: " "unprognostic (2.05e-1)" "unprognostic (1.09e-1)" "unprognostic (8.79e-3)" "unprognostic (1.08e-1)" "unprognostic (1.66e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.52e-2)" "unprognostic (8.33e-2)" "unprognostic (8.06e-2)" "unprognostic (2.15e-1)" "unprognostic (1.87e-2)" "unprognostic (6.04e-2)" "prognostic favorable (2.41e-12)" "unprognostic (9.46e-3)" "unprognostic (1.99e-1)" "unprognostic (6.53e-2)" "unprognostic (3.84e-2)" ICMT "HSTE14, PCCMT, PPMT" ENSG00000116237 "Isoprenylcysteine carboxyl methyltransferase" O60725 1 6221193-6235972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 90.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Region enriched" "Detected in all" 5 "cerebellum: 112.8" "Low region specificity" "Detected in all" "HPA032024, HPA032025" Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 54: Immune cells - T cell receptor" "Cluster 37: Non-specific - mRNA processing" "Cluster 4: Extravillous trophoblasts - Unknown function" 7 "HPA032024: AB_2674115, HPA032025: AB_10601819" "unprognostic (1.95e-3)" "unprognostic (3.83e-2)" "unprognostic (7.34e-2)" "unprognostic (4.40e-2)" "unprognostic (5.53e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (2.30e-2)" "unprognostic (7.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.87e-1)" "unprognostic (6.58e-2)" "unprognostic (2.11e-2)" "unprognostic (4.11e-1)" "unprognostic (5.27e-1)" "unprognostic (8.97e-2)" "unprognostic (1.99e-3)" INSIG1 "CL-6, MGC1405" ENSG00000186480 "Insulin induced gene 1" O15503 7 155297776-155310235 "Plasma proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 547.3" "Cell type enriched" "Detected in all" 7 "Langerhans cells: 5100.7" "Cancer enriched" "Detected in all" 5 "liver cancer: 142.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "intermediate monocyte: 273.2;non-classical monocyte: 503.5" "Lineage enriched" "Detected in all" 6 "monocytes: 503.5" "Cancer enhanced" "Detected in all" "Myeloma: 314.2" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071524 Uncertain Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Dendritic cells - Antigen presentation" 2 Vesicles "HPA071524: " "unprognostic (8.11e-2)" "unprognostic (3.22e-1)" "unprognostic (2.91e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (3.83e-2)" "unprognostic (2.05e-2)" "unprognostic (3.06e-1)" "unprognostic (1.60e-2)" "unprognostic (1.52e-1)" "unprognostic (4.64e-2)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.62e-4)" "unprognostic (4.97e-2)" INSIG2 ENSG00000125629 "Insulin induced gene 2" Q9Y5U4 2 118088452-118110997 "Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033861 Uncertain NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" 34 "CAB033861: AB_2249149" "unprognostic (3.84e-3)" "unprognostic (4.54e-3)" "unprognostic (1.84e-1)" "unprognostic (7.00e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-1)" "unprognostic (7.30e-2)" "unprognostic (7.41e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (2.40e-1)" "prognostic unfavorable (4.11e-6)" "unprognostic (1.40e-1)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "unprognostic (3.75e-2)" ITPR1 "ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29" ENSG00000150995 "Inositol 1,4,5-trisphosphate receptor type 1" Q14643 3 4493345-4847506 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 280.6;Inhibitory neurons: 176.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in all" "cerebellum: 697.2" "Region enhanced" "Detected in all" "cerebellum: 273.5" "HPA014765, HPA016487" Approved Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 8: Neurons - Neuronal signaling" 3 Vesicles "HPA014765: AB_1851843, HPA016487: AB_1851842" "unprognostic (1.92e-1)" "unprognostic (5.04e-2)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (2.16e-2)" "unprognostic (3.61e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.92e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.40e-1)" ITPR2 "CFAP48, IP3R2" ENSG00000123104 "Inositol 1,4,5-trisphosphate receptor type 2" Q14571 12 26335352-26833194 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 43.0" "Cell type enhanced" "Detected in many" "Astrocytes: 523.0;Excitatory neurons: 278.0;Microglial cells: 766.7;Oligodendrocyte precursor cells: 414.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059144, HPA062260" Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "Endoplasmic reticulum" Nucleoplasm "HPA059144: AB_2683925, HPA062260: AB_2684728" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.37e-2)" "unprognostic (3.59e-3)" "unprognostic (8.70e-2)" "unprognostic (1.66e-1)" "unprognostic (8.61e-2)" "unprognostic (2.06e-2)" "unprognostic (1.63e-1)" "unprognostic (1.54e-2)" "unprognostic (2.82e-1)" "unprognostic (9.13e-2)" "unprognostic (3.99e-2)" "unprognostic (3.76e-1)" JKAMP "C14orf100, CDA06, HSPC213, HSPC327, JAMP" ENSG00000050130 "JNK1/MAPK8 associated membrane protein" Q9P055 14 59484443-59505410 "Cancer-related genes, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 219.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031172, HPA071650" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 51: Thyroid gland - Unknown function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Mixed function" Vesicles Nucleoplasm "HPA031172: AB_10670563, HPA071650: AB_2686429" "unprognostic (1.48e-1)" "unprognostic (2.19e-2)" "unprognostic (4.95e-2)" "unprognostic (5.88e-2)" "unprognostic (2.54e-1)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.09e-6)" "unprognostic (2.68e-1)" "unprognostic (3.52e-1)" "unprognostic (1.16e-1)" "unprognostic (3.09e-1)" "unprognostic (3.14e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.36e-1)" "unprognostic (1.73e-1)" KCNA1 "AEMK, HUK1, Kv1.1, MBK1, RBK1" ENSG00000111262 "Potassium voltage-gated channel subfamily A member 1" Q09470 12 4909905-4918256 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "brain: 52.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.8;Excitatory neurons: 38.3;Horizontal cells: 21.4;Inhibitory neurons: 17.9;Oligodendrocyte precursor cells: 15.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "lung cancer: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074471 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 13 "HPA074471: " "unprognostic (6.39e-3)" "unprognostic (2.64e-1)" "unprognostic (1.09e-1)" "unprognostic (8.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.79e-2)" "unprognostic (4.69e-3)" "unprognostic (2.48e-1)" "unprognostic (8.77e-5)" "unprognostic (6.30e-2)" "unprognostic (1.08e-4)" KCNA10 Kv1.8 ENSG00000143105 "Potassium voltage-gated channel subfamily A member 10" Q16322 1 110517217-110519175 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Neuronal - Sensory perception" 5 "unprognostic (2.96e-2)" KCNA2 "HK4, Kv1.2" ENSG00000177301 "Potassium voltage-gated channel subfamily A member 2" P16389 1 110519837-110631474 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 32.1;retina: 9.4" "Cell type enhanced" "Detected in some" "Astrocytes: 47.4;Early spermatids: 16.9;Excitatory neurons: 35.5;Horizontal cells: 33.4;Inhibitory neurons: 35.6;Muller glia cells: 15.6;Oligodendrocyte precursor cells: 34.0" "Cancer enhanced" "Detected in some" "glioma: 1.2;testis cancer: 1.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Lineage enriched" "Detected in single" 8 "T-cells: 1.3" "Group enriched" "Detected in some" 5 "Bone cancer: 8.0;Myeloma: 3.0" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB001976 Enhanced NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" 1 "CAB001976: " "unprognostic (1.84e-2)" "unprognostic (9.70e-3)" "unprognostic (1.97e-1)" "unprognostic (2.98e-1)" "unprognostic (7.17e-3)" "unprognostic (6.68e-3)" "unprognostic (5.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.29e-1)" "unprognostic (4.50e-3)" "unprognostic (3.08e-3)" "unprognostic (2.93e-4)" "unprognostic (2.15e-1)" "unprognostic (3.55e-1)" "unprognostic (6.41e-2)" "unprognostic (2.83e-1)" KCNA3 "HLK3, HPCN3, Kv1.3, MK3" ENSG00000177272 "Potassium voltage-gated channel subfamily A member 3" P22001 1 110653560-110674940 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.9;lung: 2.1;lymphoid tissue: 2.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 12.7;Inhibitory neurons: 57.6;Plasma cells: 49.8;T-cells: 24.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 5.6;MAIT T-cell: 5.3;memory CD4 T-cell: 8.5;memory CD8 T-cell: 9.6;naive B-cell: 2.6;naive CD4 T-cell: 5.0;naive CD8 T-cell: 4.6;T-reg: 8.5" "Group enriched" "Detected in many" 6 "B-cells: 2.6;T-cells: 9.6" "Cancer enriched" "Detected in some" 5 "Myeloma: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Colon - T-cells, Skin - T-cells, Testis - Spermatocytes, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016625 Approved NA NA "Cluster 11: T-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: T-cells - T-cell receptor" 2 "HPA016625: AB_2669407" "unprognostic (2.17e-2)" "unprognostic (5.07e-3)" "unprognostic (3.92e-3)" "unprognostic (1.20e-2)" "unprognostic (2.35e-1)" "unprognostic (1.76e-5)" "unprognostic (1.70e-4)" "unprognostic (8.48e-2)" "unprognostic (1.49e-2)" "unprognostic (5.92e-4)" "unprognostic (1.81e-2)" "unprognostic (3.96e-2)" "unprognostic (1.39e-1)" "unprognostic (3.13e-2)" "unprognostic (2.99e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" KCNA4 "HK1, HPCN2, KCNA4L, Kv1.4, PCN2" ENSG00000182255 "Potassium voltage-gated channel subfamily A member 4" P22459 11 30009730-30017030 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cataract, Disease variant, Dystonia, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.9;brain: 7.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.7;Cardiomyocytes: 3.5;Excitatory neurons: 7.9;Horizontal cells: 6.9;Mesothelial cells: 6.8;Muller glia cells: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001977, HPA016422" Approved NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 3 "CAB001977: , HPA016422: AB_1855574" "unprognostic (1.12e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (2.73e-2)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (2.24e-1)" "unprognostic (1.15e-2)" "unprognostic (6.71e-2)" "unprognostic (1.17e-1)" KCNB1 Kv2.1 ENSG00000158445 "Potassium voltage-gated channel subfamily B member 1" Q14721 20 49293394-49484297 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Exocytosis, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "retina: 111.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 134.9;Cone photoreceptor cells: 309.2;Excitatory neurons: 145.6;Inhibitory neurons: 85.9;Rod photoreceptor cells: 352.3" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.5;Rhabdoid: 4.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001979, HPA042434" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "CAB001979: , HPA042434: AB_2677996" "unprognostic (4.51e-1)" "unprognostic (1.72e-1)" "unprognostic (6.54e-3)" "unprognostic (4.87e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-1)" "unprognostic (8.09e-2)" "unprognostic (6.22e-2)" "unprognostic (5.31e-1)" "unprognostic (8.32e-2)" "unprognostic (1.87e-3)" "unprognostic (1.37e-1)" "unprognostic (1.31e-2)" "unprognostic (2.07e-3)" "unprognostic (8.17e-2)" "unprognostic (9.35e-2)" "unprognostic (5.25e-4)" KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.2;lymphoid tissue: 2.2;retina: 4.4" "Group enriched" "Detected in some" 11 "Cone photoreceptor cells: 178.4;Excitatory neurons: 269.5;Inhibitory neurons: 230.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.8" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane" "Nucleoli, Midbody" "HPA065970: AB_2685591" "unprognostic (9.87e-3)" "unprognostic (1.71e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-2)" "unprognostic (2.72e-1)" "unprognostic (6.93e-5)" "unprognostic (5.53e-3)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" KCNC1 Kv3.1 ENSG00000129159 "Potassium voltage-gated channel subfamily C member 1" P48547 11 17734774-17856804 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "brain: 102.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.7;Excitatory neurons: 46.6;Horizontal cells: 272.6;Inhibitory neurons: 115.5" "Group enriched" "Detected in some" 5 "glioma: 1.1;testis cancer: 0.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.3;neutrophil: 1.3" "Lineage enriched" "Detected in single" 7 "granulocytes: 3.3" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.7" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047634, HPA048249" Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 2 "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA047634: AB_2680109, HPA048249: " "unprognostic (1.79e-2)" "unprognostic (2.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.09e-3)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (7.04e-5)" "unprognostic (5.89e-2)" "unprognostic (7.32e-4)" "unprognostic (1.29e-1)" "unprognostic (5.44e-2)" "unprognostic (1.05e-2)" "unprognostic (7.83e-2)" KCNC2 Kv3.2 ENSG00000166006 "Potassium voltage-gated channel subfamily C member 2" Q96PR1 12 75040077-75209839 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 38.8" "Group enriched" "Detected in some" 10 "Excitatory neurons: 377.2;Inhibitory neurons: 1368.9" "Group enriched" "Detected in some" 8 "breast cancer: 1.5;prostate cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.2;Sarcoma: 1.0" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019664, CAB022571" Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" "CAB022571: , HPA019664: AB_1855578" "unprognostic (2.01e-1)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "unprognostic (5.58e-3)" "unprognostic (4.46e-2)" "unprognostic (3.39e-2)" KCNC3 "Kv3.3, SCA13" ENSG00000131398 "Potassium voltage-gated channel subfamily C member 3" Q14003 19 50311937-50333515 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.2;thyroid gland: 50.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 19.4;Excitatory neurons: 15.1;Glandular and luminal cells: 14.9;Inhibitory neurons: 17.6;monocytes: 16.5;Secretory cells: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018041 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" "HPA018041: AB_1855579" "unprognostic (8.05e-2)" "unprognostic (2.34e-2)" "unprognostic (3.01e-4)" "unprognostic (4.41e-2)" "unprognostic (3.84e-2)" "unprognostic (1.91e-2)" "unprognostic (2.79e-2)" "unprognostic (1.12e-2)" "unprognostic (1.46e-1)" "unprognostic (1.59e-1)" "unprognostic (3.94e-3)" "unprognostic (2.10e-5)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.68e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-2)" "unprognostic (1.19e-1)" KCND1 Kv4.1 ENSG00000102057 "Potassium voltage-gated channel subfamily D member 1" Q9NSA2 X 48961378-48971844 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.4;Peritubular cells: 4.0;Rod photoreceptor cells: 4.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000524, HPA001066" Supported Uncertain Nucleoplasm Yes No "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Fibroblasts - ECM organization" Nucleoplasm "HPA000524: AB_2666013, HPA001066: AB_1079662" "unprognostic (6.00e-2)" "unprognostic (2.58e-1)" "unprognostic (1.01e-4)" "unprognostic (2.19e-4)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" "unprognostic (2.79e-1)" "unprognostic (8.13e-3)" "unprognostic (1.13e-2)" "unprognostic (2.41e-3)" "prognostic favorable (2.66e-6)" "unprognostic (2.61e-1)" "unprognostic (4.30e-11)" "unprognostic (3.13e-2)" "unprognostic (3.49e-1)" "unprognostic (7.64e-2)" "unprognostic (2.22e-3)" KCND2 "KIAA1044, Kv4.2, RK5" ENSG00000184408 "Potassium voltage-gated channel subfamily D member 2" Q9NZV8 7 120273175-120750337 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 36.3" "Group enriched" "Detected in some" 11 "Excitatory neurons: 667.4;Inhibitory neurons: 1026.1;Oligodendrocyte precursor cells: 1832.4" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.9" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029068 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA029068: AB_10601436" "unprognostic (4.22e-1)" "unprognostic (2.79e-4)" "unprognostic (3.79e-2)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-3)" "unprognostic (9.07e-3)" "unprognostic (1.03e-1)" "unprognostic (1.14e-1)" "unprognostic (9.77e-3)" "unprognostic (1.51e-1)" "unprognostic (4.51e-4)" "unprognostic (4.07e-5)" "unprognostic (2.71e-2)" "unprognostic (2.92e-2)" "unprognostic (1.83e-3)" KCND3 "KSHIVB, Kv4.3, SCA19, SCA22" ENSG00000171385 "Potassium voltage-gated channel subfamily D member 3" Q9UK17 1 111770662-111989668 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.6;Cardiomyocytes: 36.9;Excitatory neurons: 102.1;Hepatocytes: 32.7;Horizontal cells: 40.9;Inhibitory neurons: 84.6;Late spermatids: 34.4;Oligodendrocyte precursor cells: 42.9" "Cancer enhanced" "Detected in many" "prostate cancer: 8.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.6" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029452 Approved NA NA "Cluster 28: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" 1 "HPA029452: AB_10602239" "unprognostic (1.11e-2)" "unprognostic (1.73e-3)" "unprognostic (1.71e-1)" "unprognostic (2.60e-2)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (1.41e-1)" "unprognostic (9.48e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-2)" "unprognostic (1.40e-1)" "unprognostic (7.44e-2)" "unprognostic (3.64e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-3)" "unprognostic (6.64e-3)" KCNH1 "eag, eag1, h-eag, hEAG, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134165 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 16.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 516.4;Inhibitory neurons: 249.8;Oligodendrocytes: 108.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Adrenocortical cancer: 20.7" "Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014551, HPA019445, HPA076421" Enhanced Supported Vesicles NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 3 Vesicles "HPA014551: AB_2669038, HPA019445: AB_1852118, HPA076421: " "unprognostic (9.12e-2)" "unprognostic (4.82e-3)" "unprognostic (2.63e-1)" "unprognostic (6.70e-2)" "unprognostic (3.56e-1)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (9.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.77e-2)" "unprognostic (1.42e-3)" "unprognostic (1.17e-1)" "unprognostic (8.89e-2)" "unprognostic (1.36e-1)" "unprognostic (9.70e-2)" KCNH3 "BEC1, elk2, Kv12.2" ENSG00000135519 "Potassium voltage-gated channel subfamily H member 3" Q9ULD8 12 49539030-49558337 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 86.9;pituitary gland: 25.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 12.6;Excitatory neurons: 56.3;Inhibitory neurons: 18.5;Late spermatids: 10.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 9.8" "Group enriched" "Detected in all" 6 "amygdala: 74.5;basal ganglia: 55.7;cerebral cortex: 82.6;hippocampal formation: 75.7;white matter: 63.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 5.5" "Lung - Respiratory ciliated cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (5.69e-3)" "unprognostic (1.36e-1)" "unprognostic (8.87e-4)" "unprognostic (8.24e-3)" "unprognostic (7.54e-2)" "unprognostic (2.38e-2)" "unprognostic (3.63e-2)" "unprognostic (2.66e-1)" "unprognostic (9.91e-3)" "unprognostic (5.28e-2)" "unprognostic (6.39e-5)" "unprognostic (1.68e-1)" "unprognostic (1.07e-4)" "unprognostic (5.52e-3)" "unprognostic (2.67e-1)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" KCNH4 "elk1, Kv12.3" ENSG00000089558 "Potassium voltage-gated channel subfamily H member 4" Q9UQ05 17 42156891-42181142 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 7.2" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 6.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basal ganglia: 33.1;cerebral cortex: 9.7;thalamus: 8.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.5;Neuroblastoma: 6.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (3.07e-3)" "unprognostic (1.02e-2)" "unprognostic (4.02e-2)" "unprognostic (1.70e-1)" "unprognostic (9.30e-2)" "unprognostic (2.08e-3)" "unprognostic (4.59e-3)" "unprognostic (1.56e-1)" "unprognostic (2.41e-1)" "unprognostic (9.92e-2)" "unprognostic (4.77e-3)" "unprognostic (1.58e-1)" "unprognostic (1.36e-6)" "unprognostic (9.52e-2)" "unprognostic (2.66e-1)" "unprognostic (6.47e-2)" "unprognostic (1.72e-3)" KCNH5 "eag2, H-EAG2, hEAG2, Kv10.2" ENSG00000140015 "Potassium voltage-gated channel subfamily H member 5" Q8NCM2 14 62699464-63102037 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.3;retina: 4.3" "Group enriched" "Detected in some" 11 "Bipolar cells: 47.3;Excitatory neurons: 178.8;Horizontal cells: 51.0;Inhibitory neurons: 71.0;Oligodendrocyte precursor cells: 61.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.4;cervical cancer: 1.2" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030487, HPA072351" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" Centrosome "Nucleoplasm, Cytosol" "HPA030487: AB_10609995, HPA072351: " "unprognostic (1.16e-1)" "unprognostic (7.23e-2)" "unprognostic (1.25e-1)" "unprognostic (4.23e-2)" "unprognostic (2.70e-1)" "unprognostic (1.12e-1)" "unprognostic (1.50e-1)" "unprognostic (1.76e-2)" "unprognostic (8.45e-2)" "unprognostic (2.66e-1)" "unprognostic (1.70e-3)" "unprognostic (3.11e-1)" KCNH7 "erg3, HERG3, Kv11.3" ENSG00000184611 "Potassium voltage-gated channel subfamily H member 7" Q9NS40 2 162371407-162838767 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4;retina: 1.5" "Group enriched" "Detected in some" 6 "Excitatory neurons: 663.4;Inhibitory neurons: 337.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Lung - Neutrophil_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 5 "amygdala: 21.6;cerebral cortex: 85.1;hippocampal formation: 55.9;olfactory bulb: 53.9" HPA018039 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Neurons - Neuronal signaling" "HPA018039: AB_1852125" "unprognostic (1.80e-1)" "unprognostic (2.68e-1)" "unprognostic (2.66e-1)" "unprognostic (5.55e-2)" "unprognostic (3.05e-2)" "unprognostic (5.51e-2)" "unprognostic (8.12e-3)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.69e-1)" "unprognostic (3.30e-2)" "unprognostic (3.52e-2)" "unprognostic (7.55e-3)" "unprognostic (2.76e-3)" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.68e-2)" KCNH8 "elk3, Kv12.1" ENSG00000183960 "Potassium voltage-gated channel subfamily H member 8" Q96L42 3 19148510-19535642 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.3;pituitary gland: 10.4;retina: 3.3" "Group enriched" "Detected in many" 39 "Oligodendrocyte precursor cells: 311.3;Oligodendrocytes: 921.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.4" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.0;Neuroblastoma: 2.4" "Colon - Enteric glia cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA016586, HPA077537, HPA077773" Approved Supported "Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane" "HPA016586: AB_1852127, HPA077537: , HPA077773: " "unprognostic (6.68e-3)" "unprognostic (1.68e-1)" "unprognostic (2.99e-2)" "unprognostic (8.56e-6)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.88e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (1.69e-1)" "unprognostic (5.04e-3)" "unprognostic (2.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (3.89e-2)" "unprognostic (8.71e-5)" "unprognostic (1.72e-1)" KCNK1 "DPK, K2p1.1, TWIK-1" ENSG00000135750 "Potassium two pore domain channel subfamily K member 1" O00180 1 233614106-233672514 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 106.9;choroid plexus: 72.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 152.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 70 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 70 "dendritic cells: 6.9" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 160.5" "HPA016049, CAB022588" Approved Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 65: Cerebellum - Nervous system development" "Cluster 5: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" 8 Vesicles "CAB022588: , HPA016049: AB_1855571" "unprognostic (7.06e-3)" "unprognostic (1.76e-1)" "unprognostic (4.64e-2)" "unprognostic (7.46e-2)" "unprognostic (9.15e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.84e-4)" "unprognostic (4.32e-2)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (7.29e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" KCNK10 "K2p10.1, PPP1R97, TREK-2, TREK2" ENSG00000100433 "Potassium two pore domain channel subfamily K member 10" P57789 14 88180103-88326907 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;intestine: 4.9;stomach 1: 2.5" "Cell type enhanced" "Detected in some" "dendritic cells: 51.3;Excitatory neurons: 42.4;Inhibitory neurons: 16.3;Oligodendrocyte precursor cells: 35.4;Oligodendrocytes: 11.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 62 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in single" 100 "dendritic cells: 10.0" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.5" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030462 Approved NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "HPA030462: AB_10601919" "unprognostic (9.52e-3)" "unprognostic (1.17e-1)" "unprognostic (1.94e-2)" "unprognostic (1.08e-1)" "unprognostic (8.20e-2)" "unprognostic (1.45e-1)" "unprognostic (1.18e-1)" "unprognostic (2.25e-1)" "unprognostic (4.58e-1)" "unprognostic (1.23e-2)" "unprognostic (2.70e-1)" "unprognostic (2.45e-1)" "unprognostic (6.97e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-1)" "unprognostic (4.26e-3)" KCNK12 "K2p12.1, THIK-2, THIK2" ENSG00000184261 "Potassium two pore domain channel subfamily K member 12" Q9HB15 2 47509290-47570985 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 17.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.9;Excitatory neurons: 18.3;Extravillous trophoblasts: 40.0;Inhibitory neurons: 29.1;Oocytes: 14.7;Rod photoreceptor cells: 12.1" "Cancer enriched" "Detected in single" 12 "testis cancer: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 2.5;lymphoma: 1.7;Myeloma: 1.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 37: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 65: Neurons - Synaptic function" "unprognostic (6.10e-2)" "unprognostic (1.24e-1)" "unprognostic (6.02e-3)" "unprognostic (3.29e-2)" "unprognostic (2.50e-1)" "unprognostic (3.77e-2)" "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (2.54e-2)" "unprognostic (2.14e-1)" "unprognostic (6.55e-3)" "unprognostic (2.12e-1)" "unprognostic (1.12e-6)" "unprognostic (1.36e-1)" "unprognostic (1.34e-1)" "unprognostic (3.06e-2)" "unprognostic (2.25e-1)" KCNK16 "K2p16.1, TALK-1, TALK1" ENSG00000095981 "Potassium two pore domain channel subfamily K member 16" Q96T55 6 39314698-39322968 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pancreas: 22.9;stomach 1: 10.1" "Cell type enriched" "Detected in some" 11 "Pancreatic endocrine cells: 13.6" "Cancer enriched" "Detected in some" 17 "pancreatic cancer: 13.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 10 "basophil: 2.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.1" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 10.8" "Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 "unprognostic (3.29e-2)" "unprognostic (3.48e-1)" KCNK17 "K2p17.1, TALK-2, TALK2, TASK-4, TASK4" ENSG00000124780 "Potassium two pore domain channel subfamily K member 17" Q96T54 6 39299001-39314461 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 7.5;thyroid gland: 6.3" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Microglial cells: 17.0;Pancreatic endocrine cells: 18.7;Smooth muscle cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 63.9" "Lineage enriched" "Detected in many" 34 "dendritic cells: 63.9" "Cancer enhanced" "Detected in some" "Leukemia: 5.6;thyroid cancer: 3.4" "Colon - Colon enteroendocrine cells" "Not detected" "Not detected" HPA043892 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 28: Dendritic cells - Antigen presentation" "Plasma membrane, Cytosol" Nucleoplasm "HPA043892: AB_10962838" "unprognostic (5.33e-3)" "unprognostic (6.42e-2)" "unprognostic (1.33e-1)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "unprognostic (4.09e-2)" "unprognostic (4.95e-1)" "unprognostic (2.35e-1)" "unprognostic (1.71e-2)" "unprognostic (2.54e-1)" "unprognostic (3.77e-11)" "unprognostic (5.89e-2)" "unprognostic (5.36e-1)" "unprognostic (2.82e-1)" "unprognostic (3.86e-3)" KCNK18 "K2p18.1, TRESK, TRESK-2, TRESK2, TRIK" ENSG00000186795 "Potassium two pore domain channel subfamily K member 18" Q7Z418 10 117197489-117210299 "Disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "choroid plexus: 2.9;hypothalamus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044739 Uncertain NA NA "Cluster 36: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 11: Late spermatids - Unknown function" "HPA044739: AB_10795008" KCNK2 "K2p2.1, TREK-1" ENSG00000082482 "Potassium two pore domain channel subfamily K member 2" O95069 1 215005775-215237090 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "adrenal gland: 51.4" "Group enriched" "Detected in some" 10 "Excitatory neurons: 19.0;Inhibitory neurons: 51.6;Microglial cells: 28.6;Oligodendrocyte precursor cells: 42.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 13.3" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "unprognostic (3.43e-2)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (3.81e-4)" "unprognostic (2.58e-1)" "unprognostic (3.58e-2)" "unprognostic (3.48e-3)" "unprognostic (1.26e-1)" "unprognostic (1.49e-2)" "unprognostic (1.82e-1)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (2.98e-6)" "unprognostic (1.63e-2)" "unprognostic (4.37e-2)" "unprognostic (7.69e-3)" "unprognostic (7.46e-3)" KCNK4 "K2p4.1, TRAAK" ENSG00000182450 "Potassium two pore domain channel subfamily K member 4" Q9NYG8 11 64291302-64300031 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 55 "brain: 13.4" "Group enriched" "Detected in some" 5 "Astrocytes: 2.8;Excitatory neurons: 8.7;Inhibitory neurons: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (1.85e-1)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" KCNK5 "K2p5.1, TASK-2, TASK2" ENSG00000164626 "Potassium two pore domain channel subfamily K member 5" O95279 6 39188971-39229475 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 34.4;kidney: 36.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 53.4;Cytotrophoblasts: 28.2;Distal enterocytes: 43.4;Proximal enterocytes: 55.6;Salivary duct cells: 34.9;Syncytiotrophoblasts: 40.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA059148 Uncertain Approved Nucleoplasm NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 24 Nucleoplasm "HPA059148: AB_2683929" "unprognostic (1.46e-1)" "prognostic favorable (3.29e-4)" "unprognostic (1.08e-1)" "unprognostic (2.92e-3)" "unprognostic (8.09e-4)" "unprognostic (3.97e-2)" "unprognostic (2.33e-1)" "unprognostic (9.57e-3)" "unprognostic (7.14e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (2.98e-1)" "prognostic favorable (4.98e-7)" "unprognostic (2.34e-1)" "unprognostic (7.13e-2)" "unprognostic (1.03e-2)" "prognostic favorable (4.45e-4)" KCNMA1 "KCa1.1, mSLO1, SLO" ENSG00000156113 "Potassium calcium-activated channel subfamily M alpha 1" Q12791 10 76869601-77638369 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 134.1" "Cell type enhanced" "Detected in many" "Astrocytes: 446.8;Bipolar cells: 485.5;Excitatory neurons: 989.5;Inhibitory neurons: 610.3;Oligodendrocyte precursor cells: 664.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5;non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054648 Approved NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" "HPA054648: AB_2682556" "unprognostic (1.25e-1)" "unprognostic (2.23e-2)" "unprognostic (1.86e-2)" "unprognostic (5.29e-2)" "unprognostic (9.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" "unprognostic (2.81e-2)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (4.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.26e-2)" "unprognostic (1.42e-2)" "unprognostic (5.19e-2)" "unprognostic (1.42e-2)" "unprognostic (3.99e-3)" KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43780976 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 122.7" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 223.3;Syncytiotrophoblasts: 783.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Stomach - Proteolysis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 7 "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 191.0;stomach 1: 96.2" "Cell type enhanced" "Detected in many" "Microglial cells: 68.0" "Cancer enhanced" "Detected in all" "colorectal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "colorectal cancer: 32.2;Gastric cancer: 20.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Stomach - Parietal cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA048553, HPA071107" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Endoplasmic reticulum" "Plasma membrane" "HPA048553: AB_2680438, HPA071107: " "unprognostic (6.02e-2)" "unprognostic (2.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (8.07e-2)" "unprognostic (8.81e-2)" "unprognostic (1.58e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-3)" "prognostic favorable (9.85e-4)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (5.27e-2)" KCNQ2 "BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, Kv7.2" ENSG00000075043 "Potassium voltage-gated channel subfamily Q member 2" O43526 20 63400208-63472677 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 136.8" "Group enriched" "Detected in some" 5 "Early spermatids: 19.5;Excitatory neurons: 59.7;Horizontal cells: 30.2;Inhibitory neurons: 35.9;Oligodendrocyte precursor cells: 47.6;Spermatogonia: 31.1" "Cancer enriched" "Detected in some" 9 "glioma: 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 18.5;Neuroblastoma: 51.2" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016642, HPA057112" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Endoplasmic reticulum" "HPA016642: AB_1855555, HPA057112: AB_2683339" "unprognostic (2.35e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-4)" "unprognostic (8.21e-6)" "unprognostic (6.18e-2)" "unprognostic (7.58e-2)" "unprognostic (6.06e-2)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (1.92e-1)" "unprognostic (9.96e-2)" "unprognostic (9.39e-2)" "unprognostic (1.43e-5)" "unprognostic (4.36e-2)" "unprognostic (1.02e-1)" "unprognostic (1.81e-1)" "unprognostic (2.70e-2)" KCNQ4 "DFNA2, Kv7.4" ENSG00000117013 "Potassium voltage-gated channel subfamily Q member 4" P56696 1 40783787-40840452 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Hearing, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 5.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.9;Inhibitory neurons: 9.3;Muller glia cells: 3.4;Skeletal myocytes: 5.9;Smooth muscle cells: 3.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018305 Uncertain NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" "HPA018305: AB_1855556" "unprognostic (1.42e-2)" "unprognostic (1.56e-1)" "unprognostic (8.43e-3)" "unprognostic (4.59e-3)" "unprognostic (8.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" "unprognostic (5.86e-2)" "unprognostic (4.34e-2)" "unprognostic (6.64e-2)" "unprognostic (1.20e-1)" "unprognostic (7.40e-2)" "unprognostic (5.18e-4)" "unprognostic (2.68e-1)" "unprognostic (1.22e-1)" "unprognostic (3.17e-2)" "unprognostic (3.44e-2)" KCNS2 Kv9.2 ENSG00000156486 "Potassium voltage-gated channel modifier subfamily S member 2" Q9ULS6 8 98426958-98432853 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 2.9;Excitatory neurons: 4.3;Horizontal cells: 3.1;Inhibitory neurons: 1.6;Leydig cells: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051417 Uncertain NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 9: Endometrial stromal cells - Transcription" 3 "HPA051417: AB_2681478" "unprognostic (7.83e-2)" "unprognostic (9.39e-3)" "unprognostic (5.25e-2)" "unprognostic (2.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (4.27e-2)" "unprognostic (4.58e-2)" "unprognostic (1.47e-1)" "unprognostic (5.30e-5)" "unprognostic (2.43e-2)" "unprognostic (1.42e-2)" "unprognostic (2.31e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-3)" KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 83.0;tongue: 43.8" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 32.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Connective tissue cells - ECM organization" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: AB_1852155" "unprognostic (5.62e-2)" "unprognostic (4.27e-3)" "unprognostic (6.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (3.30e-1)" "unprognostic (9.47e-3)" "unprognostic (9.06e-2)" "unprognostic (8.45e-2)" "unprognostic (5.82e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" KCNT1 "KCa4.1, KIAA1422, SLACK, Slo2.2" ENSG00000107147 "Potassium sodium-activated channel subfamily T member 1" Q5JUK3 9 135702185-135795508 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 44.5;lymphoid tissue: 15.3;skeletal muscle: 12.9" "Group enriched" "Detected in some" 6 "Excitatory neurons: 58.0;Inhibitory neurons: 52.7" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "Neuroblastoma: 5.6" "Heart muscle - Cardiomyocytes, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 56.2" HPA059880 Uncertain NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" "HPA059880: AB_2684149" "unprognostic (1.50e-3)" "unprognostic (1.72e-2)" "unprognostic (2.07e-3)" "unprognostic (2.98e-13)" "unprognostic (9.26e-2)" "unprognostic (7.73e-2)" "unprognostic (9.60e-2)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (1.30e-3)" "unprognostic (9.89e-2)" "unprognostic (6.20e-2)" "unprognostic (4.89e-7)" "unprognostic (9.15e-2)" "unprognostic (2.70e-1)" "unprognostic (2.26e-1)" "unprognostic (1.66e-2)" KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 212.4;Inhibitory neurons: 229.3;Oligodendrocyte precursor cells: 291.5" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.0" "Adipose visceral - Mesothelial cells, Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 83: Liver - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" Vesicles "HPA051218: AB_2681392" "unprognostic (5.06e-2)" "unprognostic (2.94e-2)" "unprognostic (8.01e-2)" "unprognostic (5.10e-6)" "unprognostic (1.22e-3)" "unprognostic (1.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "unprognostic (9.56e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.67e-5)" "unprognostic (3.30e-4)" "unprognostic (2.95e-2)" "unprognostic (4.75e-1)" "unprognostic (1.72e-3)" KCNU1 "KCa5.1, Kcnma3, KCNMC1, Slo3" ENSG00000215262 "Potassium calcium-activated channel subfamily U member 1" A8MYU2 8 36784324-36936125 "Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 6.8" "Group enriched" "Detected in some" 20 "Early spermatids: 68.2;Late spermatids: 25.3" "Cancer enhanced" "Detected in single" "liver cancer: 0.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA063317 Uncertain "Plasma membrane" NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Early spermatids - Unknown function" "Plasma membrane" "HPA063317: " "unprognostic (2.42e-3)" "unprognostic (4.26e-2)" "unprognostic (2.07e-1)" "unprognostic (4.76e-3)" "unprognostic (7.57e-2)" "unprognostic (1.12e-1)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (7.73e-2)" "unprognostic (1.24e-2)" MBOAT7 "BB1, hMBOA-7, LENG4, LPIAT1, LPLAT, LPLAT11" ENSG00000125505 "Membrane bound O-acyltransferase domain containing 7" Q96N66 19 54173412-54189882 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 105.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "basophil: 157.4;eosinophil: 265.9;neutrophil: 239.0" "Lineage enriched" "Detected in all" 11 "granulocytes: 265.9" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055967 Approved Approved Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Neutrophils - Degranulation" 2 Cytosol "HPA055967: AB_2682990" "unprognostic (1.89e-2)" "unprognostic (2.60e-2)" "unprognostic (2.60e-1)" "unprognostic (3.31e-1)" "unprognostic (3.54e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (5.55e-6)" "prognostic unfavorable (5.13e-4)" "unprognostic (5.36e-2)" "unprognostic (2.31e-2)" "unprognostic (1.08e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (6.62e-5)" "unprognostic (1.31e-1)" "unprognostic (4.75e-2)" "unprognostic (3.95e-1)" "prognostic favorable (4.31e-4)" MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin TRP cation channel 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 101.6;Kupffer cells: 88.5;Macrophages: 74.1;monocytes: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 118.2;classical monocyte: 45.3;eosinophil: 106.1;intermediate monocyte: 95.7;neutrophil: 41.4;non-classical monocyte: 105.7" "Group enriched" "Detected in all" 5 "granulocytes: 118.2;monocytes: 105.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031763, CAB032637, HPA069495" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 47: Spleen - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 58: Macrophages - Innate immune response" 2 "Golgi apparatus, Vesicles" Nucleoplasm "CAB032637: AB_2142964, HPA031763: AB_10600822, HPA069495: " "unprognostic (5.51e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.30e-2)" "unprognostic (2.66e-1)" "unprognostic (4.07e-2)" "unprognostic (8.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.36e-1)" "prognostic favorable (5.67e-4)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" MCOLN2 "FLJ36691, TRP-ML2, TRPML2" ENSG00000153898 "Mucolipin TRP cation channel 2" Q8IZK6 1 84925583-84997113 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Innate immunity, Ion transport, Protein transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 8.5;intestine: 14.6;lymphoid tissue: 12.7" "Cell type enhanced" "Detected in many" "B-cells: 40.1;dendritic cells: 79.7;Early spermatids: 67.0;Glandular and luminal cells: 27.3;Langerhans cells: 114.9;Schwann cells: 32.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 29.6" "Group enriched" "Detected in many" 15 "B-cells: 10.3;dendritic cells: 29.6;T-cells: 8.8" "Cancer enriched" "Detected in many" 5 "lymphoma: 27.9" "Adipose subcutaneous - T-cells, Liver - T-cells, Testis - Early spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019114 Uncertain NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA019114: AB_1853645" "unprognostic (3.02e-2)" "unprognostic (5.67e-2)" "unprognostic (3.07e-1)" "unprognostic (1.44e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.38e-1)" "prognostic favorable (2.56e-4)" "unprognostic (8.92e-2)" "unprognostic (1.48e-2)" "unprognostic (6.84e-2)" "unprognostic (2.21e-2)" "unprognostic (3.12e-4)" "unprognostic (3.68e-2)" "unprognostic (4.69e-2)" "unprognostic (1.24e-1)" "unprognostic (4.23e-2)" MCOLN3 "FLJ11006, TRP-ML3, TRPML3" ENSG00000055732 "Mucolipin TRP cation channel 3" Q8TDD5 1 85018082-85048500 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 42.4;epididymis: 13.8;parathyroid gland: 34.1" "Group enriched" "Detected in many" 6 "Enteroendocrine cells: 53.4;Melanocytes: 211.3" "Cancer enriched" "Detected in many" 6 "melanoma: 8.0" "Group enriched" "Detected in many" 5 "cerebral cortex: 8.3;choroid plexus: 7.4;hippocampal formation: 7.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.1" "Lung - Fibroblast_1, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.2" "HPA018106, HPA062137" Enhanced Approved Nucleoli,Cytosol NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 29: Forebrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Nucleoli, Cytosol" "HPA018106: AB_1853647, HPA062137: AB_2684695" "unprognostic (5.91e-2)" "unprognostic (1.24e-1)" "unprognostic (1.49e-2)" "unprognostic (3.21e-5)" "unprognostic (2.25e-1)" "unprognostic (8.80e-3)" "unprognostic (3.97e-3)" "unprognostic (1.13e-1)" "unprognostic (2.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.45e-3)" "unprognostic (3.09e-2)" "unprognostic (7.32e-5)" "unprognostic (6.36e-3)" "unprognostic (2.61e-1)" "unprognostic (6.11e-2)" "unprognostic (6.43e-2)" MFSD8 "CLN7, MGC33302" ENSG00000164073 "Major facilitator superfamily domain containing 8" Q8NHS3 4 127917799-127966034 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044802 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Non-specific - Transcription" Vesicles Nucleoplasm "HPA044802: AB_10963221" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (8.10e-2)" "unprognostic (1.57e-1)" "unprognostic (4.12e-2)" "unprognostic (1.18e-1)" "unprognostic (8.99e-2)" "unprognostic (2.19e-2)" "unprognostic (8.69e-2)" "unprognostic (4.51e-2)" "unprognostic (3.44e-2)" "unprognostic (3.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.61e-3)" "unprognostic (3.14e-1)" "prognostic favorable (2.21e-4)" MIP "AQP0, LIM1, MP26" ENSG00000135517 "Major intrinsic protein of lens fiber" P30301 12 56449502-56469166 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Transport, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA014940 Supported NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Non-specific - Transcription" 35 "HPA014940: AB_2669122" "unprognostic (6.48e-2)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (7.14e-2)" "unprognostic (3.96e-2)" "unprognostic (2.90e-3)" "unprognostic (1.72e-1)" "unprognostic (3.47e-1)" "unprognostic (1.51e-5)" "unprognostic (4.56e-3)" "unprognostic (6.75e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-2)" "unprognostic (3.27e-1)" "unprognostic (2.62e-1)" "unprognostic (8.82e-2)" MT-ATP6 "ATP6, ATPase-6, MTATP6, RP, Su6m" ENSG00000198899 "Mitochondrially encoded ATP synthase membrane subunit 6" P00846 MT 8527-9207 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Cardiomyopathy, Disease variant, Leber hereditary optic neuropathy, Leigh syndrome, Neuropathy, Primary mitochondrial disease, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 233045.7" "Cell type enhanced" "Detected in all" "Bipolar cells: 67222.5;Cardiomyocytes: 48451.6;Cone photoreceptor cells: 41589.9;Horizontal cells: 35882.2;Rod photoreceptor cells: 53785.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 15232.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 15232.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 23: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "unprognostic (2.97e-1)" "unprognostic (4.16e-1)" "unprognostic (1.86e-2)" "unprognostic (4.55e-2)" "unprognostic (8.45e-3)" "unprognostic (1.66e-1)" "prognostic favorable (3.79e-4)" "unprognostic (6.47e-2)" "unprognostic (2.39e-1)" "unprognostic (1.44e-2)" "prognostic favorable (7.64e-4)" "unprognostic (6.01e-2)" "unprognostic (4.64e-2)" "unprognostic (1.46e-1)" "unprognostic (1.37e-1)" "unprognostic (3.56e-1)" "unprognostic (2.52e-3)" MYADM ENSG00000179820 "Myeloid associated differentiation marker" Q96S97 19 53864763-53876435 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 574.0;Lymphatic endothelial cells: 459.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 208.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Spermatocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056301 Approved "Nuclear speckles" NA NA 27000 "Cluster 21: Neutrophils - Unknown function" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Monocytes - Innate immune response" 9 "Nuclear speckles" "HPA056301: " "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (2.94e-1)" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (8.15e-4)" "unprognostic (3.97e-2)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (7.71e-7)" "unprognostic (2.28e-3)" "unprognostic (1.29e-1)" "unprognostic (2.37e-2)" "unprognostic (6.14e-3)" MYMK "MYOMAKER, TMEM226, TMEM8C" ENSG00000187616 "Myomaker, myoblast fusion factor" A6NI61 9 133514586-133528612 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Myogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 43 "Sarcoma: 7.9" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA051846, HPA055785" Uncertain NA NA "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 50: Connective tissue cells - ECM organization" "HPA051846: AB_2681636, HPA055785: AB_2682920" "unprognostic (9.17e-3)" "unprognostic (8.63e-2)" "unprognostic (3.76e-1)" "unprognostic (1.13e-1)" "unprognostic (1.03e-1)" "unprognostic (5.37e-1)" "unprognostic (9.32e-2)" "unprognostic (1.91e-1)" NDC1 "FLJ10407, NET3, TMEM48" ENSG00000058804 "NDC1 transmembrane nucleoporin" Q9BTX1 1 53765478-53838463 "Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069751, HPA070882" Approved Supported "Nuclear membrane,Plasma membrane,Actin filaments" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 15: Non-specific - Mixed function" "Nuclear membrane" "Plasma membrane, Actin filaments" "HPA069751: AB_2686189, HPA070882: AB_2686320" "unprognostic (2.51e-1)" "unprognostic (1.93e-1)" "prognostic favorable (4.48e-5)" "unprognostic (6.96e-3)" "unprognostic (1.31e-1)" "unprognostic (1.36e-3)" "prognostic unfavorable (7.52e-7)" "unprognostic (3.46e-3)" "unprognostic (1.53e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.58e-4)" "unprognostic (9.27e-2)" "unprognostic (6.22e-3)" "unprognostic (3.00e-3)" "unprognostic (4.38e-2)" "unprognostic (9.24e-2)" "unprognostic (6.07e-2)" NIPAL3 "DJ462O23.2, NPAL3, SLC57A5" ENSG00000001461 "NIPA like domain containing 3" Q6P499 1 24415802-24472976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.3" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 98.6;Oligodendrocytes: 85.5;Prostatic glandular cells: 192.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Smooth muscle cells, Prostate - Prostate glandular cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039978 Approved Approved Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Prostatic glandular cells - Transcription" 8 Nucleoplasm "HPA039978: AB_10697712" "unprognostic (9.36e-2)" "unprognostic (7.63e-2)" "unprognostic (2.88e-2)" "unprognostic (1.19e-2)" "unprognostic (5.96e-2)" "unprognostic (5.38e-2)" "unprognostic (3.72e-3)" "unprognostic (3.60e-2)" "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (2.79e-1)" "unprognostic (3.14e-1)" "prognostic favorable (3.03e-7)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (3.95e-4)" "unprognostic (2.85e-1)" NOX1 "GP91-2, MOX1, NOH-1, NOH-1L, NOH1" ENSG00000007952 "NADPH oxidase 1" Q9Y5S8 X 100843324-100874359 "Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 24 "intestine: 69.5" "Group enriched" "Detected in some" 44 "Distal enterocytes: 59.5;Enteroendocrine cells: 34.1;Intestinal goblet cells: 20.8;Paneth cells: 26.9;Undifferentiated cells: 57.7" "Cancer enriched" "Detected in many" 18 "colorectal cancer: 82.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "colorectal cancer: 16.4" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 45: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "unprognostic (8.31e-2)" "unprognostic (2.07e-3)" "prognostic favorable (9.71e-4)" "unprognostic (1.67e-2)" "unprognostic (3.37e-1)" "unprognostic (6.55e-3)" "unprognostic (5.48e-3)" "unprognostic (8.68e-3)" "unprognostic (1.32e-1)" "unprognostic (5.23e-2)" "unprognostic (1.18e-1)" "unprognostic (3.86e-3)" "unprognostic (2.56e-3)" "unprognostic (1.64e-1)" "unprognostic (1.78e-2)" "unprognostic (5.28e-2)" "unprognostic (1.81e-3)" NOX4 "KOX, KOX-1" ENSG00000086991 "NADPH oxidase 4" Q9NPH5 11 89324353-89498187 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 133.1" "Cell type enriched" "Detected in many" 4 "Proximal tubular cells: 132.0" "Cancer enhanced" "Detected in many" "renal cancer: 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 6.5" "Breast - Endothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "unprognostic (2.91e-2)" "unprognostic (1.08e-1)" "unprognostic (1.74e-3)" "unprognostic (6.58e-3)" "unprognostic (1.92e-1)" "unprognostic (2.33e-1)" "unprognostic (8.83e-3)" "unprognostic (8.95e-3)" "unprognostic (3.80e-1)" "unprognostic (6.88e-2)" "unprognostic (1.56e-2)" "unprognostic (1.73e-1)" "prognostic favorable (6.14e-4)" "unprognostic (1.99e-4)" "unprognostic (9.71e-2)" "unprognostic (5.69e-2)" "unprognostic (3.03e-3)" NPC1 SLC65A1 ENSG00000141458 "NPC intracellular cholesterol transporter 1" O15118 18 23506184-23586506 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 169.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 71.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026618, CAB070132, HPA077445" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Alveolar cells - Lung function" 2 "Nucleoplasm, Vesicles" "CAB070132: AB_10001101, HPA026618: AB_1854580, HPA077445: " "unprognostic (1.74e-1)" "unprognostic (1.53e-3)" "unprognostic (2.67e-1)" "unprognostic (1.25e-1)" "unprognostic (3.20e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" "unprognostic (7.36e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-3)" "unprognostic (2.78e-2)" "unprognostic (1.89e-1)" "unprognostic (2.73e-2)" "unprognostic (1.38e-1)" "unprognostic (2.08e-3)" NPC1L1 SLC65A2 ENSG00000015520 "NPC1 like intracellular cholesterol transporter 1" Q9UHC9 7 44512535-44541330 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 52.7;liver: 46.9" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 33.5" "Group enriched" "Detected in many" 5 "liver cancer: 8.5;pancreatic cancer: 7.8;stomach cancer: 4.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Gastric cancer: 9.2;liver cancer: 7.6" "Kidney - Proximal tubular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB070127, CAB070128" Enhanced NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Hepatocytes - Metabolism" "CAB070127: AB_10002744, CAB070128: AB_10000815" "unprognostic (2.96e-2)" "unprognostic (2.23e-1)" "unprognostic (7.57e-3)" "unprognostic (8.43e-2)" "unprognostic (1.62e-1)" "unprognostic (2.07e-1)" "unprognostic (9.40e-2)" "unprognostic (6.75e-2)" "unprognostic (1.44e-1)" "unprognostic (1.96e-2)" "unprognostic (4.51e-2)" "unprognostic (7.59e-2)" "unprognostic (8.08e-10)" "unprognostic (1.64e-2)" "unprognostic (2.83e-1)" "unprognostic (3.62e-2)" "unprognostic (5.83e-2)" OCSTAMP "C20orf123, dJ257E24.3" ENSG00000149635 "Osteoclast stimulatory transmembrane protein" Q9BR26 20 46540946-46550654 "Predicted membrane proteins, Transporters" Differentiation "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Langerhans cells: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Myeloma: 4.7" "Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031116 Uncertain NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Dendritic cells - Antigen presentation" "HPA031116: AB_10600758" "unprognostic (2.77e-1)" "unprognostic (3.04e-1)" "unprognostic (8.80e-2)" "unprognostic (5.02e-2)" "unprognostic (2.42e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "unprognostic (9.59e-2)" "unprognostic (2.08e-1)" OPN4 "melanopsin, MOP" ENSG00000122375 "Opsin 4" Q9UHM6 10 86654518-86666460 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Biological rhythms, Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.9;brain: 2.8;skeletal muscle: 2.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.7;Horizontal cells: 1.3;Inhibitory neurons: 1.8;Smooth muscle cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039147 Approved NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "HPA039147: AB_10673304" "unprognostic (3.67e-3)" "unprognostic (1.40e-2)" "unprognostic (3.02e-2)" "unprognostic (1.62e-1)" "unprognostic (7.03e-3)" "unprognostic (2.89e-2)" "unprognostic (3.26e-1)" "unprognostic (9.54e-2)" "unprognostic (5.68e-2)" "unprognostic (8.88e-3)" "unprognostic (1.93e-6)" "unprognostic (4.10e-2)" "unprognostic (5.58e-2)" "unprognostic (6.76e-2)" OPN5 "dJ402H5.1, neuropsin, TMEM13" ENSG00000124818 "Opsin 5" Q6U736 6 47781982-47832780 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.5" "Group enriched" "Detected in some" 12 "Early spermatids: 31.3;Late spermatids: 25.6;Spermatocytes: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA026084 Supported NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Cluster 36: Late spermatids - Unknown function" "HPA026084: AB_2671807" "unprognostic (1.95e-1)" "unprognostic (6.18e-2)" "unprognostic (4.84e-1)" "unprognostic (1.07e-1)" OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225724-53251637 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;prostate: 1.6;skeletal muscle: 1.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.4;Extravillous trophoblasts: 9.2;Glandular and luminal cells: 8.6;Inhibitory neurons: 9.7;Leydig cells: 5.1;Prostatic glandular cells: 18.3" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.1;prostate cancer: 3.8" "Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: AB_2732770" "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (8.70e-3)" "unprognostic (3.73e-2)" "unprognostic (6.74e-2)" "unprognostic (2.22e-3)" "unprognostic (8.09e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-4)" "unprognostic (1.61e-1)" OPRM1 "MOP, MOR1" ENSG00000112038 "Opioid receptor mu 1" P35372 6 154010496-154246867 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;testis: 2.8" "Cell type enhanced" "Detected in some" "Early spermatids: 36.1;Excitatory neurons: 39.8;Inhibitory neurons: 22.4;Late spermatids: 34.8;Microglial cells: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 4.3" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014509, HPA067435" Enhanced Supported NA NA "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 13 "HPA014509: AB_1854801, HPA067435: " "unprognostic (7.34e-2)" "unprognostic (6.91e-2)" OR10J3 OR10J3P ENSG00000196266 "Olfactory receptor family 10 subfamily J member 3" 1 159313720-159314659 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Lymphoma - Unknown function" OR4K3 OR4K3P ENSG00000176290 "Olfactory receptor family 4 subfamily K member 3 (gene/pseudogene)" 14 19868197-19869143 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA OR4Q2 OR4Q2P ENSG00000196383 "Olfactory receptor family 4 subfamily Q member 2 (gene/pseudogene)" 14 19999913-20004760 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 29: Monocytes - Innate immune response" OR56A5 OR56A5P ENSG00000188691 "Olfactory receptor family 56 subfamily A member 5" P0C7T3 11 5967177-5968494 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 63: Late spermatids - Spermatogenesis" "unprognostic (9.82e-2)" OR5AK3P OR5AK3 ENSG00000181282 "Olfactory receptor family 5 subfamily AK member 3 pseudogene" 11 56971050-56971979 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 22: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" OR5H8 OR5H8P ENSG00000232535 "Olfactory receptor family 5 subfamily H member 8 (gene/pseudogene)" 3 98306752-98312843 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 55: Lymphoma - Immune response" "unprognostic (8.70e-2)" OR9A2 ENSG00000179468 "Olfactory receptor family 9 subfamily A member 2" Q8NGT5 7 143026200-143027132 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 38 "Oligodendrocytes: 71.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 51: Oligodendrocytes - Unknown function" PAQR4 FLJ30002 ENSG00000162073 "Progestin and adipoQ receptor family member 4" Q8N4S7 16 2969270-2973484 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 143.5;retina: 61.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.1;Oligodendrocytes: 57.7;Rod photoreceptor cells: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 3.6" "Lineage enriched" "Detected in single" 9 "monocytes: 3.6" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA068394 Approved Vesicles NA Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 54: Non-specific - Transcription" "Cluster 66: Photoreceptor cells - Visual perception" Vesicles "HPA068394: AB_2685980" "unprognostic (1.93e-1)" "unprognostic (2.75e-1)" "unprognostic (6.73e-2)" "unprognostic (1.30e-3)" "unprognostic (8.39e-2)" "unprognostic (3.00e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (2.62e-2)" "unprognostic (7.59e-2)" "unprognostic (9.65e-3)" "unprognostic (5.21e-2)" "unprognostic (8.59e-2)" "prognostic unfavorable (3.01e-6)" "prognostic favorable (1.70e-4)" "unprognostic (1.36e-1)" "unprognostic (3.79e-2)" "unprognostic (6.06e-3)" PAQR6 "FLJ22672, PRdelta" ENSG00000160781 "Progestin and adipoQ receptor family member 6" Q6TCH4 1 156243320-156248117 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 28 "brain: 1313.0" "Cell type enhanced" "Detected in many" "Astrocytes: 41.8;Muller glia cells: 57.7;Oligodendrocytes: 60.6;Schwann cells: 15.2" "Cancer enriched" "Detected in all" 6 "glioma: 34.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 5.7" "Lineage enriched" "Detected in single" 7 "NK-cells: 5.7" "Cancer enhanced" "Detected in all" "Myeloma: 27.1" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA No "Cluster 15: NK-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 10: Muller glia cells - Visual perception" 3 "unprognostic (1.64e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (7.42e-2)" "unprognostic (5.52e-2)" "unprognostic (4.50e-3)" "unprognostic (4.75e-1)" "unprognostic (2.25e-1)" "unprognostic (2.57e-1)" "unprognostic (3.13e-1)" "unprognostic (4.25e-3)" "prognostic unfavorable (1.99e-4)" "prognostic unfavorable (1.58e-8)" "unprognostic (1.26e-2)" "unprognostic (1.34e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.86e-4)" PCNX4 "C14orf135, PCNXL4" ENSG00000126773 "Pecanex 4" Q63HM2 14 60091911-60169133 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002076, HPA003390" Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 16: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 55: Non-specific - Transcription" 1 Cytosol "HPA002076: AB_1078322, HPA003390: AB_2066703" "unprognostic (2.00e-1)" "unprognostic (1.45e-1)" "unprognostic (1.89e-1)" "unprognostic (9.87e-2)" "unprognostic (2.18e-1)" "unprognostic (2.94e-1)" "unprognostic (3.83e-3)" "unprognostic (2.01e-1)" "unprognostic (1.54e-1)" "unprognostic (3.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.81e-1)" "prognostic favorable (6.84e-5)" "unprognostic (2.13e-1)" "unprognostic (2.08e-1)" "unprognostic (4.14e-2)" "unprognostic (8.59e-2)" PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 41.9" "Cell type enhanced" "Detected in many" "Astrocytes: 93.2;Bipolar cells: 79.2;Cardiomyocytes: 209.8;Horizontal cells: 95.7;Inhibitory neurons: 75.1;Smooth muscle cells: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.4" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.4" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 30: Heart muscle - Heart development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 2 "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" PDE3B HcGIP1 ENSG00000152270 "Phosphodiesterase 3B" Q13370 11 14643804-14872044 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" Angiogenesis Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 62.3" "Cell type enhanced" "Detected in many" "Astrocytes: 162.9;Excitatory neurons: 135.7;Inhibitory neurons: 151.5;Microglial cells: 183.4;Oligodendrocyte precursor cells: 111.3;T-cells: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 3.9;T-cells: 6.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056111 Approved "Endoplasmic reticulum" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 11: Liver - Plasma proteins" "Cluster 35: Non-specific - DNA binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 5 "Endoplasmic reticulum" "HPA056111: AB_2683041" "unprognostic (1.05e-1)" "unprognostic (2.86e-2)" "unprognostic (4.12e-2)" "unprognostic (2.76e-3)" "unprognostic (4.25e-1)" "unprognostic (1.84e-3)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "prognostic favorable (7.91e-4)" "unprognostic (1.77e-1)" "unprognostic (2.33e-2)" "unprognostic (1.39e-2)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (9.03e-3)" PGAP2 "CWH43-N, FRAG1, MRT17, MRT21" ENSG00000148985 "Post-GPI attachment to proteins 2" Q9UHJ9 11 3797724-3826371 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "GPI-anchor biosynthesis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "epididymis: 211.1" "Cell type enhanced" "Detected in many" "Early spermatids: 122.1;Late spermatids: 306.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Fibroblast_1, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063099 Approved Approved Microtubules NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Late spermatids - Unknown function" 2 Microtubules "HPA063099: AB_2684940" "unprognostic (1.94e-1)" "unprognostic (1.14e-1)" "unprognostic (2.19e-1)" "unprognostic (3.18e-2)" "unprognostic (5.13e-2)" "unprognostic (6.06e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (3.07e-1)" "unprognostic (1.11e-1)" "unprognostic (6.44e-2)" "unprognostic (3.85e-2)" "unprognostic (4.66e-3)" "unprognostic (4.13e-2)" "unprognostic (2.17e-2)" "unprognostic (2.67e-2)" PGAP3 "CAB2, MGC9753, PER1, PERLD1, PP1498" ENSG00000161395 "Post-GPI attachment to proteins phospholipase 3" Q96FM1 17 39671122-39696797 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "breast cancer: 77.4;Esophageal cancer: 77.4" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016591 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Protein processing" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Plasma membrane, Cytosol" "HPA016591: AB_1855203" "unprognostic (1.29e-1)" "unprognostic (8.64e-2)" "unprognostic (1.65e-1)" "unprognostic (6.53e-3)" "unprognostic (9.19e-2)" "unprognostic (1.68e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.61e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.57e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.89e-4)" "unprognostic (5.16e-2)" "unprognostic (1.31e-1)" "unprognostic (9.05e-2)" "unprognostic (1.94e-2)" PGAP6 "M83, TMEM6, TMEM8, TMEM8A" ENSG00000129925 "Post-GPI attachment to proteins 6" Q9HCN3 16 370788-387113 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 77.7;Syncytiotrophoblasts: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051281, HPA064673" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 4: Neutrophils - Degranulation" "Cluster 46: Testis - Spermatogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 54: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" 9 Nucleoplasm "Cytokinetic bridge" "HPA051281: AB_2681418, HPA064673: AB_2685317" "unprognostic (5.84e-2)" "unprognostic (6.13e-2)" "unprognostic (3.85e-2)" "unprognostic (3.21e-2)" "unprognostic (5.77e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-3)" "unprognostic (1.56e-2)" "unprognostic (8.89e-2)" "unprognostic (7.73e-2)" "unprognostic (3.43e-1)" "unprognostic (1.38e-2)" "prognostic favorable (1.29e-5)" "unprognostic (4.20e-3)" "unprognostic (3.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.48e-1)" PHTF1 PHTF ENSG00000116793 "Putative homeodomain transcription factor 1" Q9UMS5 1 113696831-113759489 "Plasma proteins, Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 226.1;Excitatory neurons: 90.2;Inhibitory neurons: 98.4;Late spermatids: 125.7;Spermatocytes: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059486 Approved "Nucleoli,Nuclear bodies" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Spermatocytes - Spermatogenesis" "Nuclear bodies" Nucleoli "HPA059486: " "unprognostic (1.52e-1)" "unprognostic (3.33e-1)" "unprognostic (2.58e-2)" "unprognostic (4.54e-2)" "unprognostic (5.92e-2)" "unprognostic (1.62e-2)" "unprognostic (6.55e-2)" "unprognostic (1.30e-1)" "unprognostic (3.30e-3)" "unprognostic (1.70e-3)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.21e-6)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.25e-1)" PIGB ENSG00000069943 "Phosphatidylinositol glycan anchor biosynthesis class B" Q92521 15 55318960-55355648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 33.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039929 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 73: B-cells - B-cell function" "Plasma membrane, Cytosol" "HPA039929: AB_10673539" "unprognostic (1.91e-2)" "unprognostic (7.45e-2)" "unprognostic (3.00e-1)" "unprognostic (2.03e-2)" "unprognostic (2.96e-2)" "unprognostic (4.65e-2)" "unprognostic (2.04e-1)" "unprognostic (3.37e-3)" "unprognostic (7.52e-2)" "unprognostic (3.52e-2)" "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (2.13e-1)" "unprognostic (1.30e-1)" "unprognostic (2.86e-1)" "unprognostic (5.93e-2)" "unprognostic (4.24e-2)" PIGF ENSG00000151665 "Phosphatidylinositol glycan anchor biosynthesis class F" Q07326 2 46580937-46617055 "Disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051389 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 35: Respiratory epithelial cells - Unknown function" 8 "HPA051389: AB_2681464" "unprognostic (3.85e-3)" "unprognostic (5.42e-2)" "unprognostic (1.11e-3)" "unprognostic (8.18e-2)" "unprognostic (2.56e-1)" "unprognostic (4.52e-3)" "prognostic unfavorable (1.39e-5)" "unprognostic (4.97e-2)" "unprognostic (9.29e-3)" "unprognostic (6.08e-2)" "unprognostic (5.89e-2)" "unprognostic (9.40e-2)" "unprognostic (1.02e-1)" "unprognostic (7.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.04e-2)" "unprognostic (6.71e-2)" PIGV FLJ20477 ENSG00000060642 "Phosphatidylinositol glycan anchor biosynthesis class V" Q9NUD9 1 26787054-26800659 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 51.5;Late spermatids: 96.2;Spermatocytes: 73.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054181 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Testis - Spermatid development" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Spermatocytes - Spermatogenesis" 3 Cytosol "Endoplasmic reticulum" "HPA054181: " "unprognostic (2.08e-1)" "unprognostic (6.53e-2)" "unprognostic (1.32e-3)" "unprognostic (1.96e-2)" "unprognostic (2.02e-2)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (8.40e-2)" "unprognostic (4.44e-2)" "prognostic favorable (7.60e-7)" "unprognostic (1.71e-1)" "unprognostic (4.24e-1)" "unprognostic (8.92e-2)" "unprognostic (5.96e-3)" PKD1L2 KIAA1879 ENSG00000166473 "Polycystin 1 like 2 (gene/pseudogene)" Q7Z442 16 81100875-81220370 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 7.7;choroid plexus: 8.4;heart muscle: 7.7" "Cell type enhanced" "Detected in some" "Astrocytes: 7.7;Basal prostatic cells: 28.0;Cardiomyocytes: 7.4;Endometrial stromal cells: 10.3;Fibroblasts: 9.1;Leydig cells: 8.8;Oligodendrocytes: 11.6" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.8" "Region enriched" "Detected in many" 5 "choroid plexus: 32.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Basal prostatic cells - Lipid metabolism" "unprognostic (3.92e-1)" "unprognostic (1.48e-1)" "unprognostic (1.21e-1)" "unprognostic (2.88e-1)" "unprognostic (5.38e-2)" "unprognostic (7.35e-2)" "unprognostic (1.17e-2)" "unprognostic (6.58e-3)" "unprognostic (3.22e-1)" "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (1.90e-1)" "unprognostic (1.11e-6)" "unprognostic (5.91e-3)" "unprognostic (1.59e-1)" "unprognostic (2.30e-1)" "unprognostic (7.23e-2)" PKD2L1 "PCL, PKD2L, PKDL, TRPP3" ENSG00000107593 "Polycystin 2 like 1, transient receptor potential cation channel" Q9P0L9 10 100288149-100330264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.7;retina: 12.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.0;Early spermatids: 10.3;Hofbauer cells: 13.7;Horizontal cells: 19.5;Kupffer cells: 9.7;Late spermatids: 21.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 2.2;Uterine cancer: 1.0" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB022621, HPA070002" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 17: Neuronal - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "Actin filaments, Cytosol" "CAB022621: , HPA070002: " "unprognostic (2.67e-1)" "unprognostic (3.66e-7)" "unprognostic (8.07e-3)" "unprognostic (4.38e-2)" "unprognostic (4.70e-2)" "unprognostic (5.31e-2)" "unprognostic (2.19e-1)" "unprognostic (2.85e-2)" "unprognostic (2.01e-1)" "unprognostic (9.25e-2)" "unprognostic (1.55e-1)" "unprognostic (9.37e-2)" "unprognostic (1.49e-4)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" PKD2L2 TRPP5 ENSG00000078795 "Polycystin 2 like 2, transient receptor potential cation channel" Q9NZM6 5 137887968-137942747 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 7.9" "Group enriched" "Detected in many" 4 "Early spermatids: 58.8;Spermatocytes: 43.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041903, HPA043634" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 78: Testis - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" "Plasma membrane" Cytosol "HPA041903: AB_2677734, HPA043634: AB_2678591" "unprognostic (7.53e-3)" "unprognostic (2.21e-2)" "unprognostic (1.90e-1)" "unprognostic (3.59e-1)" "unprognostic (4.04e-1)" "unprognostic (1.21e-2)" "unprognostic (3.06e-1)" "unprognostic (1.40e-4)" "unprognostic (1.64e-2)" "unprognostic (2.13e-2)" "unprognostic (3.00e-2)" "unprognostic (5.85e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.28e-2)" "unprognostic (1.22e-1)" PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55534969 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 310.9;Leydig cells: 217.4;Prostatic glandular cells: 734.7" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "prostate cancer: 117.5" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 6 "Plasma membrane" "CAB033331: AB_2168044, HPA047815: AB_2680164" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favorable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 102.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 221.3;Ciliated cells: 211.6;Club cells: 236.1;Ductal cells: 340.4;Ionocytes: 251.4;Proximal enterocytes: 205.6;Rod photoreceptor cells: 242.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.3;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 40 "T-cells: 6.6" "Low cancer specificity" "Detected in many" "Liver - Cholangiocyte, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 354.8;Fibroblasts: 410.5;Leydig cells: 864.7;Peritubular cells: 305.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 65.5" "Kidney - Endothelial cells, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 23: B-cells - Immunoglobulins" "Cluster 62: Connective tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" PLPP4 "DPPL2, PPAPDC1, PPAPDC1A" ENSG00000203805 "Phospholipid phosphatase 4" Q5VZY2 10 120457227-120592065 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "brain: 3.8" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 142.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045188 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 76: Oligodendrocyte precursor - Unknown function" 29 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA045188: AB_2679246" "unprognostic (8.19e-2)" "unprognostic (2.94e-2)" "unprognostic (8.86e-2)" "unprognostic (1.90e-3)" "unprognostic (3.45e-1)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (2.26e-3)" "unprognostic (1.55e-1)" "unprognostic (8.62e-3)" "unprognostic (2.70e-3)" "unprognostic (1.89e-1)" "unprognostic (2.40e-3)" "unprognostic (3.49e-2)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (1.21e-3)" PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 288.3;Prostatic glandular cells: 182.3;Serous glandular cells: 193.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 80.7;memory B-cell: 212.7;naive B-cell: 307.0" "Group enriched" "Detected in all" 7 "B-cells: 307.0;granulocytes: 80.7" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055777 Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 1 Vesicles "HPA055777: AB_2682915" "unprognostic (4.54e-2)" "unprognostic (2.51e-3)" "unprognostic (3.66e-2)" "prognostic favorable (1.48e-5)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (5.58e-2)" "prognostic favorable (8.72e-5)" "unprognostic (9.79e-2)" "prognostic favorable (2.42e-5)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "prognostic unfavorable (8.33e-10)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (1.57e-2)" PLPPR1 "FLJ20300, LPPR1, MGC26189, PRG-3" ENSG00000148123 "Phospholipid phosphatase related 1" Q8TBJ4 9 101028727-101325135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 24.7;kidney: 15.1" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 602.8;Oligodendrocytes: 253.7" "Group enriched" "Detected in some" 5 "glioma: 11.1;liver cancer: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.1" "Liver - Hepatocytes, Pancreas - Alpha cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014760, HPA014968, HPA014979" Supported Supported Nucleoplasm NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 76: Oligodendrocyte precursor - Unknown function" 13 Nucleoplasm "HPA014760: AB_2669084, HPA014968: AB_1855702, HPA014979: AB_2669130" "unprognostic (1.08e-2)" "unprognostic (2.79e-1)" "unprognostic (2.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (7.33e-2)" "unprognostic (3.41e-1)" "prognostic favorable (1.37e-4)" "unprognostic (2.09e-1)" "unprognostic (1.14e-1)" "unprognostic (9.86e-4)" "unprognostic (1.44e-1)" "unprognostic (1.65e-6)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (2.85e-1)" "unprognostic (4.83e-2)" PLPPR2 "LPPR2, PRG-4" ENSG00000105520 "Phospholipid phosphatase related 2" Q96GM1 19 11355386-11365698 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 114.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 71.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 71.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048973, HPA077966" Approved Uncertain Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 32: Smooth muscle cells - Muscle contraction" 20 Nucleoplasm "HPA048973: AB_2680580, HPA077966: " "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (7.10e-2)" "unprognostic (1.37e-1)" "unprognostic (9.60e-2)" "unprognostic (1.72e-1)" "prognostic favorable (6.82e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (7.46e-11)" "unprognostic (1.99e-2)" "unprognostic (1.46e-1)" "unprognostic (4.37e-2)" "unprognostic (1.17e-1)" PLPPR3 "FLJ11535, LPPR3, PRG-2, PRG2" ENSG00000129951 "Phospholipid phosphatase related 3" Q6T4P5 19 812488-821955 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 9.7;brain: 40.8;fallopian tube: 10.8" "Cell type enriched" "Detected in some" 7 "Ciliated cells: 50.2" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 29.8;Neuroblastoma: 20.8" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052293, HPA057034" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 42: Ciliated cells - Cilium assembly" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA052293: AB_2681787, HPA057034: AB_2683316" "unprognostic (7.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.33e-2)" "unprognostic (3.66e-3)" "unprognostic (1.00e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.47e-1)" "unprognostic (4.32e-1)" "unprognostic (4.51e-4)" "unprognostic (8.06e-3)" "unprognostic (1.07e-1)" "unprognostic (1.72e-12)" "unprognostic (1.21e-2)" "unprognostic (6.82e-2)" "unprognostic (8.50e-2)" "unprognostic (2.91e-1)" PLPPR4 "KIAA0455, LPPR4, PHP1, PRG-1" ENSG00000117600 "Phospholipid phosphatase related 4" Q7Z2D5 1 99264292-99309590 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 51.8" "Group enriched" "Detected in some" 5 "Excitatory neurons: 113.9;Inhibitory neurons: 158.7;Melanocytes: 67.0;Microglial cells: 45.6;Oligodendrocyte precursor cells: 91.0" "Group enriched" "Detected in many" 4 "glioma: 7.2;melanoma: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Brain cancer: 6.8;Neuroblastoma: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 65: Neurons - Synaptic function" "unprognostic (4.32e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-2)" "unprognostic (1.67e-2)" "unprognostic (2.95e-2)" "unprognostic (1.00e-2)" "unprognostic (1.17e-2)" "unprognostic (9.09e-2)" "unprognostic (9.70e-3)" "unprognostic (3.36e-2)" "unprognostic (2.21e-1)" "unprognostic (7.25e-12)" "unprognostic (1.67e-5)" "unprognostic (3.47e-1)" "unprognostic (1.34e-2)" "unprognostic (1.16e-3)" PLPPR5 "LPPR5, PAP2, PAP2D, PRG5" ENSG00000117598 "Phospholipid phosphatase related 5" Q32ZL2 1 98890245-99227929 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.7;retina: 1.6;testis: 2.0" "Group enriched" "Detected in some" 10 "Excitatory neurons: 54.5;Inhibitory neurons: 131.0;Oligodendrocyte precursor cells: 135.8" "Group enriched" "Detected in some" 13 "glioma: 2.7;renal cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 12.2" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018072, HPA059085" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" Cytosol "HPA018072: AB_1854958, HPA059085: AB_2732631" "unprognostic (2.57e-1)" "unprognostic (1.63e-2)" "unprognostic (1.68e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (3.18e-1)" "unprognostic (1.43e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.22e-4)" "unprognostic (1.81e-2)" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" POMT2 LGMD2N ENSG00000009830 "Protein O-mannosyltransferase 2" Q9UKY4 14 77274956-77320883 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 36.3" "Cell type enhanced" "Detected in many" "Astrocytes: 25.7;Oligodendrocytes: 28.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003663 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 78: Testis - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Oligodendrocytes - Unknown function" 1 Nucleoplasm "Nucleoli, Cytosol" "HPA003663: AB_1079655" "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (7.92e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.40e-4)" "unprognostic (7.10e-3)" "unprognostic (1.17e-1)" "unprognostic (1.68e-1)" "unprognostic (6.89e-3)" "unprognostic (1.94e-3)" "unprognostic (8.50e-3)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.75e-3)" "unprognostic (3.46e-2)" PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361690 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 15.7;bone marrow: 57.0" "Group enriched" "Detected in some" 10 "Horizontal cells: 19.5;Inhibitory neurons: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 27.0;Neuroblastoma: 70.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Neutrophil_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 6: Bone marrow - Innate immune response" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: AB_2679642, HPA052681: AB_2681912" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.36e-3)" "unprognostic (1.20e-4)" "unprognostic (2.60e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-4)" "unprognostic (9.11e-2)" "unprognostic (3.73e-4)" "unprognostic (5.28e-3)" "unprognostic (9.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "monocytes: 186.7;Oligodendrocytes: 368.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006844, HPA030760, HPA067496" Approved Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Oligodendrocytes - Unknown function" 18 "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: AB_10696211, HPA067496: AB_2685853" "unprognostic (1.67e-1)" "unprognostic (4.79e-2)" "unprognostic (7.39e-2)" "unprognostic (8.68e-3)" "unprognostic (3.84e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.65e-1)" "unprognostic (8.99e-2)" "unprognostic (8.45e-2)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "prognostic favorable (1.52e-8)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (7.12e-3)" "unprognostic (1.85e-1)" PSEN2 "AD3L, AD4, PS2, STM2" ENSG00000143801 "Presenilin 2" P49810 1 226870184-226927726 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 5.9;Melanocytes: 10.3;Plasma cells: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 49: Non-specific - Transcription" 41 "unprognostic (3.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.94e-1)" "unprognostic (3.86e-2)" "unprognostic (6.54e-2)" "unprognostic (1.64e-3)" "unprognostic (4.72e-2)" "unprognostic (1.31e-1)" "unprognostic (9.98e-2)" "unprognostic (2.73e-2)" "unprognostic (8.25e-3)" "unprognostic (8.53e-3)" "unprognostic (8.45e-2)" "unprognostic (1.17e-1)" "unprognostic (8.36e-2)" "unprognostic (1.68e-1)" "unprognostic (1.06e-1)" PTGDR "DP, DP1, PTGDR1" ENSG00000168229 "Prostaglandin D2 receptor" Q13258 14 52267698-52276724 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Mast cell degranulation" "G-protein coupled receptor, Receptor, Transducer" "Asthma, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7.6;lymphoid tissue: 6.1" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 16.2;NK-cells: 116.8;T-cells: 29.2;Undifferentiated cells: 30.6" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 68.2;MAIT T-cell: 33.5;memory CD8 T-cell: 40.9;naive CD8 T-cell: 22.6;NK-cell: 90.5" "Group enriched" "Detected in many" 33 "NK-cells: 90.5;T-cells: 68.2" "Cancer enhanced" "Detected in single" "Leukemia: 1.7" "Adipose visceral - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Stomach - Fibroblasts, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA046586, HPA049668" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 17: Choroid plexus - Cilium" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane, Cytosol" "HPA046586: , HPA049668: " "unprognostic (9.32e-3)" "unprognostic (3.31e-2)" "unprognostic (1.00e-2)" "unprognostic (2.04e-3)" "unprognostic (4.80e-2)" "unprognostic (2.70e-2)" "unprognostic (3.11e-3)" "unprognostic (5.00e-2)" "unprognostic (9.38e-3)" "unprognostic (4.94e-2)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (5.60e-8)" "unprognostic (1.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.02e-2)" "unprognostic (5.89e-2)" PTGFR FP ENSG00000122420 "Prostaglandin F receptor" P43088 1 78303884-78540701 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 19.3" "Cell type enhanced" "Detected in some" "Club cells: 21.9;Collecting duct cells: 11.7;Fibroblasts: 27.5;Inhibitory neurons: 9.9;Late spermatids: 10.9;Microglial cells: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 6.9;prostate cancer: 6.4" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "unprognostic (4.14e-2)" "unprognostic (1.35e-2)" "unprognostic (5.89e-3)" "unprognostic (6.03e-2)" "unprognostic (5.63e-2)" "unprognostic (1.45e-3)" "unprognostic (7.61e-2)" "unprognostic (2.25e-1)" "unprognostic (9.90e-2)" "unprognostic (8.46e-4)" "unprognostic (2.21e-1)" "unprognostic (5.34e-2)" "unprognostic (2.16e-4)" "unprognostic (3.21e-4)" "unprognostic (8.48e-2)" "unprognostic (2.16e-2)" "unprognostic (1.21e-3)" PTGIR IP ENSG00000160013 "Prostaglandin I2 receptor" P43119 19 46620468-46625089 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 53.8" "Cell type enriched" "Detected in some" 6 "Langerhans cells: 239.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 10 "classical monocyte: 28.3;intermediate monocyte: 65.3;myeloid DC: 20.9;non-classical monocyte: 38.9" "Group enriched" "Detected in many" 11 "dendritic cells: 20.9;monocytes: 65.3" "Cancer enhanced" "Detected in some" "Leukemia: 6.4;Neuroblastoma: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 14: Langerhans cells - Innate immune response" "unprognostic (3.79e-1)" "unprognostic (1.95e-1)" "unprognostic (2.94e-2)" "unprognostic (2.39e-1)" "unprognostic (1.03e-1)" "unprognostic (3.49e-3)" "unprognostic (4.22e-2)" "unprognostic (6.09e-2)" "unprognostic (2.12e-1)" "unprognostic (7.45e-2)" "unprognostic (4.47e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.09e-8)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.74e-4)" "unprognostic (1.16e-1)" "unprognostic (5.66e-2)" RCE1 "FACE-2, FACE2, hRCE1, RCE1A, RCE1B" ENSG00000173653 "Ras converting CAAX endopeptidase 1" Q9Y256 11 66842835-66846552 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074124 Approved NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Mixed function" 1 "HPA074124: " "unprognostic (1.11e-1)" "unprognostic (7.23e-2)" "unprognostic (1.15e-1)" "unprognostic (8.16e-3)" "unprognostic (3.11e-1)" "unprognostic (6.40e-3)" "unprognostic (1.98e-3)" "unprognostic (7.69e-3)" "unprognostic (1.39e-1)" "unprognostic (9.14e-3)" "unprognostic (2.35e-3)" "unprognostic (5.31e-3)" "unprognostic (1.06e-1)" "unprognostic (4.48e-3)" "unprognostic (2.17e-2)" "unprognostic (1.04e-1)" "unprognostic (4.28e-2)" RNF121 FLJ11099 ENSG00000137522 "Ring finger protein 121" Q9H920 11 71929018-71997597 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046041 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA046041: AB_10965850" "unprognostic (1.36e-2)" "unprognostic (8.84e-2)" "unprognostic (9.72e-2)" "unprognostic (1.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.38e-2)" "unprognostic (1.41e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (6.54e-2)" "unprognostic (1.85e-2)" "unprognostic (1.90e-1)" "prognostic favorable (2.72e-6)" "unprognostic (1.54e-1)" "unprognostic (1.81e-1)" "unprognostic (2.57e-2)" "unprognostic (1.70e-1)" RNF175 FLJ34190 ENSG00000145428 "Ring finger protein 175" Q8N4F7 4 153710160-153760024 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.1" "Group enriched" "Detected in some" 4 "Early spermatids: 92.6;Excitatory neurons: 88.3;Inhibitory neurons: 91.7;Oligodendrocyte precursor cells: 36.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bone cancer: 4.4;skin cancer: 3.9" "Colon - Colon enteroendocrine cells, Kidney - Macrophages, Liver - Neutrophils, Testis - Early spermatids, Testis - Late spermatids" HPA035837 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 8: Neurons - Neuronal signaling" 1 "HPA035837: AB_10601609" "unprognostic (3.23e-2)" "unprognostic (4.12e-2)" "unprognostic (3.34e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (3.11e-4)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-4)" "unprognostic (1.17e-1)" "unprognostic (2.96e-3)" "unprognostic (6.30e-3)" "unprognostic (1.42e-1)" "unprognostic (3.63e-4)" "unprognostic (7.25e-3)" "unprognostic (3.27e-1)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" RYR2 "ARVC2, ARVD2, VTSIP" ENSG00000198626 "Ryanodine receptor 2" Q92736 1 237042184-237833988 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Developmental protein, Ion channel, Ligand-gated ion channel, Receptor" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "heart muscle: 134.4" "Group enriched" "Detected in many" 12 "Cardiomyocytes: 2742.2;Excitatory neurons: 1274.9;Inhibitory neurons: 760.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 4.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020028 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 34: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 68: Cardiomyocytes - Muscle contraction" 2 "Nucleoplasm, Plasma membrane, Cytosol" "HPA020028: AB_1856528" "unprognostic (5.23e-3)" "unprognostic (2.15e-2)" "unprognostic (5.02e-4)" "unprognostic (6.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.99e-3)" "unprognostic (5.28e-2)" "unprognostic (1.45e-3)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (0.00e+0)" "unprognostic (2.36e-2)" "unprognostic (1.42e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" RYR3 ENSG00000198838 "Ryanodine receptor 3" Q15413 15 33310962-33866121 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.1;choroid plexus: 28.7;skeletal muscle: 23.3;tongue: 42.3" "Cell type enriched" "Detected in many" 4 "Astrocytes: 748.1" "Cancer enriched" "Detected in single" 4 "glioma: 1.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 30.4" HPA062004 Approved Vesicles NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA062004: AB_2797267" "unprognostic (5.85e-2)" "unprognostic (1.57e-1)" "unprognostic (5.30e-2)" "unprognostic (1.35e-1)" "unprognostic (1.26e-2)" "unprognostic (8.03e-4)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.85e-2)" "unprognostic (7.10e-2)" "unprognostic (8.25e-3)" "unprognostic (2.36e-1)" "unprognostic (2.48e-2)" "unprognostic (1.86e-2)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" SAMD8 "FLJ25082, SMSr" ENSG00000156671 "Sterile alpha motif domain containing 8" Q96LT4 10 75099586-75182123 "Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 19.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044402 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 55: Non-specific - Transcription" "Endoplasmic reticulum, Cytosol" "HPA044402: " "unprognostic (4.32e-1)" "unprognostic (3.14e-1)" "unprognostic (3.24e-2)" "unprognostic (7.87e-2)" "unprognostic (3.37e-2)" "unprognostic (2.77e-2)" "unprognostic (1.61e-2)" "unprognostic (1.39e-1)" "unprognostic (5.29e-1)" "unprognostic (3.12e-2)" "unprognostic (2.70e-1)" "unprognostic (4.69e-2)" "unprognostic (4.16e-3)" "unprognostic (3.89e-2)" "unprognostic (3.76e-1)" "unprognostic (2.53e-1)" "unprognostic (9.26e-3)" SCN2A "HBSCI, HBSCII, Nav1.2, SCN2A1, SCN2A2" ENSG00000136531 "Sodium voltage-gated channel alpha subunit 2" Q99250 2 165194993-165392310 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "brain: 70.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 425.4;Inhibitory neurons: 349.2;Oligodendrocyte precursor cells: 231.1" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.8" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022567 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "CAB022567: " "unprognostic (1.16e-1)" "unprognostic (3.56e-4)" "unprognostic (5.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.97e-1)" "unprognostic (8.62e-3)" "unprognostic (1.18e-1)" "unprognostic (7.25e-3)" "unprognostic (1.40e-1)" "unprognostic (2.78e-1)" "unprognostic (1.32e-2)" "unprognostic (5.21e-2)" "unprognostic (3.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.05e-1)" "unprognostic (4.88e-2)" "unprognostic (2.14e-1)" SEC61A1 ENSG00000058262 "SEC61 translocon subunit alpha 1" P61619 3 128051641-128071705 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 219.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022076 Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 3 "Endoplasmic reticulum" "CAB022076: " "unprognostic (1.84e-1)" "unprognostic (8.00e-2)" "unprognostic (8.21e-2)" "prognostic favorable (7.82e-4)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (2.84e-2)" "unprognostic (4.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.85e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.84e-9)" "unprognostic (2.73e-2)" "unprognostic (3.18e-2)" "unprognostic (8.33e-2)" "unprognostic (2.51e-2)" SERINC4 FLJ40363 ENSG00000184716 "Serine incorporator 4" A6NH21 15 43794162-43800220 "Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 14.9" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 57.8;Early spermatids: 16.7;Late spermatids: 46.9;Rod photoreceptor cells: 51.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 1: Neuronal - Visual perception" "Cluster 11: Late spermatids - Unknown function" SGMS1 "MGC17342, MOB, SMS1, TMEM23" ENSG00000198964 "Sphingomyelin synthase 1" Q86VZ5 10 50305586-50625163 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 147.9;Microglial cells: 219.2;Oligodendrocyte precursor cells: 293.8;Oligodendrocytes: 392.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Keratinocyte (other), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045191 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 76: Oligodendrocyte precursor - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA045191: AB_10959605" "unprognostic (1.13e-1)" "unprognostic (5.75e-2)" "unprognostic (1.87e-1)" "unprognostic (9.08e-2)" "unprognostic (8.69e-3)" "unprognostic (8.34e-2)" "unprognostic (7.98e-2)" "unprognostic (2.29e-1)" "unprognostic (1.30e-2)" "unprognostic (5.75e-2)" "unprognostic (9.20e-2)" "unprognostic (2.05e-1)" "prognostic favorable (1.95e-7)" "unprognostic (8.38e-2)" "unprognostic (1.95e-1)" "unprognostic (3.31e-1)" "unprognostic (3.05e-1)" SGMS2 "MGC26963, SMS2" ENSG00000164023 "Sphingomyelin synthase 2" Q8NHU3 4 107824563-107915047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 115.3;Alveolar cells type 2: 128.7;Ciliated cells: 104.5;Early spermatids: 94.6;Glandular and luminal cells: 130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 3.7;eosinophil: 2.4;intermediate monocyte: 1.5;myeloid DC: 4.2;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 35 "dendritic cells: 4.2;granulocytes: 2.4;monocytes: 3.7" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015076, HPA015541" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "Golgi apparatus" Nucleoplasm "HPA015076: AB_1857298, HPA015541: " "unprognostic (7.44e-2)" "unprognostic (2.32e-2)" "unprognostic (2.36e-2)" "unprognostic (1.87e-2)" "unprognostic (7.88e-3)" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (1.32e-1)" "unprognostic (4.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.82e-3)" "unprognostic (3.26e-1)" "prognostic favorable (1.37e-4)" "unprognostic (6.18e-2)" "unprognostic (5.63e-2)" "unprognostic (8.71e-2)" "unprognostic (5.22e-3)" SLC10A7 "C4orf13, DKFZp313H0531, DKFZp566M114, DKFZp779O2438, MGC25043" ENSG00000120519 "Solute carrier family 10 member 7" Q0GE19 4 146253975-146522372 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 42.1;Microglial cells: 48.3;Oligodendrocyte precursor cells: 58.5;Oligodendrocytes: 76.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039996 Uncertain NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 53: Non-specific - Glycosylation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA039996: AB_10673266" "unprognostic (9.44e-2)" "unprognostic (4.03e-1)" "unprognostic (3.39e-3)" "unprognostic (5.07e-2)" "unprognostic (1.01e-1)" "unprognostic (9.02e-2)" "unprognostic (7.96e-2)" "unprognostic (2.54e-1)" "unprognostic (3.55e-1)" "unprognostic (8.53e-2)" "unprognostic (2.68e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-2)" "unprognostic (8.99e-2)" "unprognostic (2.79e-1)" "unprognostic (6.69e-2)" "unprognostic (9.57e-2)" SLC12A1 "BSC, BSC-1, BSC1, CCC2, NKCC2" ENSG00000074803 "Solute carrier family 12 member 1" Q13621 15 48178438-48304078 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Bartter syndrome, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 825 "kidney: 687.0" "Group enriched" "Detected in some" 4 "Collecting duct cells: 33.1;Distal tubular cells: 92.2" "Cancer enriched" "Detected in single" 4 "renal cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014967, HPA018107" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles Nucleoplasm "HPA014967: AB_1854503, HPA018107: AB_1854504" "unprognostic (3.52e-2)" "unprognostic (1.30e-2)" "unprognostic (9.65e-2)" "unprognostic (1.74e-2)" "unprognostic (7.77e-2)" "unprognostic (1.04e-1)" "unprognostic (8.72e-2)" "unprognostic (2.06e-1)" "unprognostic (9.85e-3)" "unprognostic (2.81e-4)" "unprognostic (9.75e-2)" "unprognostic (2.61e-1)" "unprognostic (5.47e-2)" "unprognostic (2.03e-1)" "unprognostic (5.20e-4)" "unprognostic (8.52e-2)" SLC12A4 KCC1 ENSG00000124067 "Solute carrier family 12 member 4" Q9UP95 16 67943474-67969601 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 39.7;Syncytiotrophoblasts: 62.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041138 Approved Approved Endosomes NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 8 Endosomes "HPA041138: AB_10794544" "unprognostic (5.07e-2)" "unprognostic (6.18e-2)" "unprognostic (1.25e-1)" "unprognostic (2.68e-2)" "unprognostic (9.28e-2)" "unprognostic (1.48e-2)" "unprognostic (4.28e-2)" "unprognostic (3.26e-3)" "unprognostic (9.58e-2)" "unprognostic (1.55e-1)" "unprognostic (2.01e-2)" "unprognostic (1.81e-2)" "prognostic favorable (2.25e-6)" "unprognostic (6.42e-2)" "unprognostic (1.42e-1)" "unprognostic (7.64e-2)" "unprognostic (2.26e-1)" SLC12A9 CIP1 ENSG00000146828 "Solute carrier family 12 member 9" Q9BXP2 7 100826820-100867010 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 90.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067536 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 57: Lung - Lung function" "Cluster 30: White matter - Myelination" "Cluster 39: Non-specific - Transcription" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA067536: AB_2732768" "unprognostic (6.53e-2)" "unprognostic (3.65e-1)" "unprognostic (8.75e-3)" "unprognostic (3.11e-3)" "unprognostic (3.47e-2)" "unprognostic (2.37e-2)" "unprognostic (8.38e-3)" "prognostic favorable (5.97e-4)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.00e-4)" "unprognostic (2.47e-2)" "unprognostic (1.03e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.52e-2)" "unprognostic (6.00e-2)" "unprognostic (6.74e-3)" "unprognostic (6.38e-2)" SLC14A1 "HsT1341, JK, RACH1, RACH2" ENSG00000141469 "Solute carrier family 14 member 1 (Kidd blood group)" Q13336 18 45687025-45752520 "Blood group antigen proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 55.2;prostate: 75.7;urinary bladder: 87.4" "Group enriched" "Detected in many" 4 "Adipocytes: 93.3;Astrocytes: 216.7" "Group enriched" "Detected in many" 5 "glioma: 5.3;prostate cancer: 8.6;urothelial cancer: 16.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 4.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Brain cancer: 35.3;thyroid cancer: 34.9" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059570, HPA077233" Approved Supported "Plasma membrane" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Plasma membrane" "HPA059570: AB_2684066, HPA077233: " "unprognostic (2.04e-1)" "unprognostic (2.56e-3)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-2)" "unprognostic (1.84e-2)" "unprognostic (1.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.17e-2)" "unprognostic (9.99e-2)" "unprognostic (2.69e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (9.09e-2)" "unprognostic (6.93e-2)" SLC15A3 "hPTR3, PHT2" ENSG00000110446 "Solute carrier family 15 member 3" Q8IY34 11 60937060-60952653 "Metabolic proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 93.6;Kupffer cells: 60.0;Langerhans cells: 54.7;Macrophages: 85.6;monocytes: 134.2;Muller glia cells: 197.9;Schwann cells: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.0;intermediate monocyte: 12.8;memory B-cell: 4.9;myeloid DC: 6.5;neutrophil: 13.4;non-classical monocyte: 6.4;plasmacytoid DC: 10.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047880, HPA057642" Approved Supported Vesicles NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 58: Macrophages - Innate immune response" 5 Vesicles "HPA047880: AB_10959455, HPA057642: AB_2683487" "unprognostic (5.61e-2)" "prognostic favorable (4.07e-5)" "unprognostic (8.79e-2)" "unprognostic (1.67e-2)" "unprognostic (8.48e-2)" "unprognostic (9.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (9.78e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" SLC16A10 "MCT10, TAT1" ENSG00000112394 "Solute carrier family 16 member 10" Q8TF71 6 111087503-111231194 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 28.8;skeletal muscle: 39.6" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 45.8;Macrophages: 39.5;Melanocytes: 67.0;monocytes: 63.7;Skeletal myocytes: 88.8" "Cancer enriched" "Detected in many" 6 "testis cancer: 4.5" "Region enhanced" "Detected in all" "choroid plexus: 86.5" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.7;T-reg: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Stomach - Chief cells, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016860 Approved Supported "Vesicles,Cell Junctions" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 29: Monocytes - Innate immune response" 3 "Vesicles, Cell Junctions" "HPA016860: AB_2189211" "unprognostic (2.03e-1)" "unprognostic (2.08e-1)" "unprognostic (6.11e-2)" "unprognostic (3.56e-4)" "unprognostic (2.24e-1)" "unprognostic (2.15e-1)" "unprognostic (1.64e-1)" "unprognostic (1.89e-1)" "unprognostic (1.86e-3)" "unprognostic (5.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-3)" "unprognostic (2.73e-1)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (1.91e-1)" SLC16A2 "AHDS, DXS128, DXS128E, MCT7, MCT8, MRX22, XPCT" ENSG00000147100 "Solute carrier family 16 member 2" P36021 X 74421493-74533917 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 39.5" "Cell type enhanced" "Detected in many" "Astrocytes: 21.1;Hepatocytes: 52.5;Inhibitory neurons: 20.6;Oligodendrocyte precursor cells: 21.7;Peritubular cells: 20.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 66.9" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072719 Approved "Plasma membrane" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "HPA072719: AB_2686552" "prognostic unfavorable (8.88e-5)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-3)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (1.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (5.67e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (2.15e-2)" "unprognostic (1.89e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (3.16e-4)" SLC16A3 "MCT3, MCT4" ENSG00000141526 "Solute carrier family 16 member 3" O15427 17 82217934-82261129 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 191.2" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 1954.4;Syncytiotrophoblasts: 690.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 110.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophil_2, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017490, HPA021451" Approved Supported "Nuclear membrane,Plasma membrane" NA NA 260000 "Cluster 21: Neutrophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 4: Extravillous trophoblasts - Unknown function" 7 "Plasma membrane" "Nuclear membrane" "CAB017490: AB_2189333, HPA021451: AB_1853663" "unprognostic (2.49e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (4.31e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-3)" "unprognostic (4.26e-3)" "prognostic unfavorable (1.19e-7)" "prognostic unfavorable (2.02e-5)" "unprognostic (2.52e-1)" "unprognostic (2.09e-2)" "unprognostic (4.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.71e-7)" "unprognostic (2.27e-1)" "unprognostic (4.00e-2)" "unprognostic (8.00e-2)" "unprognostic (1.36e-2)" SLC16A5 "MCT5, MCT6" ENSG00000170190 "Solute carrier family 16 member 5" O15375 17 75087727-75106162 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 90.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 45.2;Collecting duct cells: 83.6;Late spermatids: 40.8;Paneth cells: 33.6;Proximal enterocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.2;neutrophil: 35.1" "Group enriched" "Detected in all" 6 "granulocytes: 35.1;monocytes: 13.2" "Low cancer specificity" "Detected in many" "Liver - Vascular Endothelial cells, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 52: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 5: Enterocytes - Absorption" 2 "unprognostic (1.86e-2)" "unprognostic (1.18e-1)" "unprognostic (1.98e-1)" "unprognostic (2.51e-2)" "unprognostic (2.90e-2)" "unprognostic (2.72e-1)" "unprognostic (6.30e-2)" "unprognostic (2.55e-1)" "unprognostic (1.61e-1)" "unprognostic (5.26e-2)" "unprognostic (8.43e-3)" "unprognostic (8.07e-2)" "unprognostic (9.63e-2)" "unprognostic (3.53e-3)" "unprognostic (5.44e-2)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" SLC19A1 "FOLT, RFC1" ENSG00000173638 "Solute carrier family 19 member 1" P41440 21 45493572-45573365 "Cancer-related genes, Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 46.1" "Group enriched" "Detected in many" 8 "Cytotrophoblasts: 151.7;Syncytiotrophoblasts: 343.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 188.5" "Immune cell enriched" "Detected in many" 4 "neutrophil: 103.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 103.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024802 Approved Approved "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Cytotrophoblasts - Mitochondria" "Plasma membrane" "HPA024802: AB_10602892" "unprognostic (4.31e-3)" "prognostic unfavorable (4.15e-4)" "unprognostic (5.23e-2)" "unprognostic (2.02e-1)" "unprognostic (3.11e-1)" "unprognostic (3.04e-2)" "unprognostic (7.34e-2)" "unprognostic (2.87e-3)" "unprognostic (4.04e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.07e-10)" "unprognostic (1.44e-1)" "unprognostic (2.31e-1)" "unprognostic (7.97e-5)" "unprognostic (3.10e-1)" SLC19A2 "ThT1, THTR1, TRMA" ENSG00000117479 "Solute carrier family 19 member 2" O60779 1 169463909-169485944 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Deafness, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 119.8;tongue: 81.8" "Cell type enhanced" "Detected in many" "Skeletal myocytes: 106.4;Syncytiotrophoblasts: 199.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006119, HPA016599" Uncertain Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 53: Fibroblasts - ECM organization" 1 Cytosol "HPA006119: AB_1079996, HPA016599: AB_1857005" "prognostic favorable (8.41e-4)" "unprognostic (8.82e-2)" "unprognostic (1.90e-1)" "unprognostic (3.29e-3)" "prognostic favorable (2.90e-4)" "unprognostic (4.45e-2)" "unprognostic (9.69e-2)" "unprognostic (1.45e-1)" "unprognostic (2.86e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.08e-1)" "unprognostic (2.09e-1)" "unprognostic (3.60e-2)" "unprognostic (2.14e-2)" SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 44.8;breast: 27.5;placenta: 23.3" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 66.3;Syncytiotrophoblasts: 166.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "liver cancer: 10.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 9 Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" SLC1A5 "AAAT, ASCT2, M7V1, RDRC" ENSG00000105281 "Solute carrier family 1 member 5" Q15758 19 46774883-46788594 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Host-virus interaction, Symport, Transport" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 96.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035239, HPA035240" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 49: Hindbrain - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 80: Non-specific - Transcription" 1 "Plasma membrane" "HPA035239: AB_10670587, HPA035240: AB_10604092" "unprognostic (8.26e-3)" "unprognostic (6.38e-2)" "unprognostic (7.24e-2)" "unprognostic (7.94e-2)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.66e-8)" "unprognostic (2.08e-1)" "unprognostic (1.06e-2)" "unprognostic (9.82e-2)" "unprognostic (9.40e-3)" "unprognostic (9.57e-3)" "prognostic unfavorable (1.18e-7)" "unprognostic (1.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.06e-2)" "unprognostic (9.83e-2)" SLC22A15 FLIPT1 ENSG00000163393 "Solute carrier family 22 member 15" Q8IZD6 1 115976513-116070054 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.3" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 232.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.3;non-classical monocyte: 1.2" "Group enriched" "Detected in many" 8 "granulocytes: 1.3;monocytes: 1.2" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019785 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 51: Oligodendrocytes - Unknown function" "HPA019785: AB_1857011" "unprognostic (3.81e-1)" "unprognostic (1.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.01e-3)" "unprognostic (5.62e-2)" "unprognostic (5.22e-2)" "unprognostic (5.85e-5)" "unprognostic (8.91e-3)" "unprognostic (1.81e-1)" "unprognostic (4.97e-2)" "unprognostic (5.15e-2)" "unprognostic (9.06e-2)" "unprognostic (7.29e-3)" "unprognostic (8.78e-3)" "unprognostic (3.44e-1)" "unprognostic (9.97e-4)" "unprognostic (1.30e-1)" SLC22A23 "C6orf85, FLJ22174" ENSG00000137266 "Solute carrier family 22 member 23" A1A5C7 6 3268962-3457050 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 233.7;Oligodendrocytes: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014697 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 60: Prostate cancer - Unknown function" "Cluster 51: Oligodendrocytes - Unknown function" 3 "Nucleoplasm, Vesicles" Cytosol "HPA014697: AB_1844371" "unprognostic (4.58e-2)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.57e-4)" "unprognostic (5.16e-3)" "unprognostic (3.25e-3)" "unprognostic (1.40e-1)" "unprognostic (4.53e-3)" "unprognostic (9.74e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (8.91e-2)" "unprognostic (4.30e-1)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" SLC22A7 "NLT, OAT2" ENSG00000137204 "Solute carrier family 22 member 7" Q9Y694 6 43295694-43305538 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "liver: 417.7" "Group enriched" "Detected in some" 11 "Hepatocytes: 186.3;Proximal tubular cells: 52.6" "Cancer enriched" "Detected in some" 37 "liver cancer: 81.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA030220 Approved NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 56: Proximal tubular cells - Amino acid metabolism" "HPA030220: AB_10603027" "unprognostic (9.17e-2)" "unprognostic (9.73e-4)" "unprognostic (2.13e-1)" "prognostic favorable (5.48e-6)" "unprognostic (1.45e-1)" "unprognostic (1.54e-3)" "unprognostic (1.74e-2)" "prognostic favorable (8.98e-4)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" SLC23A2 "KIAA0238, SLC23A1, SVCT2, YSPL2" ENSG00000089057 "Solute carrier family 23 member 2" Q9UGH3 20 4852356-5010293 "Metabolic proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 96.2;retina: 104.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 200.8;Excitatory neurons: 99.2;Inhibitory neurons: 112.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052825, HPA059314" Approved Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 17: Neuronal - Synaptic function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 69: Skin cancer - ECM organization" "Cluster 25: Bipolar cells - Visual perception" Vesicles "Golgi apparatus" "HPA052825: AB_2681965, HPA059314: AB_2683975" "unprognostic (3.83e-1)" "unprognostic (1.08e-2)" "unprognostic (1.95e-3)" "unprognostic (1.64e-3)" "unprognostic (8.05e-2)" "unprognostic (2.09e-1)" "prognostic favorable (3.35e-4)" "unprognostic (6.22e-3)" "unprognostic (2.08e-1)" "unprognostic (6.36e-3)" "prognostic favorable (7.14e-5)" "unprognostic (1.57e-1)" "unprognostic (1.60e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.08e-5)" SLC25A17 PMP34 ENSG00000100372 "Solute carrier family 25 member 17" O43808 22 40769630-40819399 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052708, HPA060972" Approved Supported Peroxisomes NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 53: Non-specific - Glycosylation" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 6: Ovarian stromal cells - Transcription" 1 Peroxisomes "HPA052708: AB_2681924, HPA060972: AB_2684400" "unprognostic (2.75e-1)" "unprognostic (1.11e-3)" "unprognostic (1.91e-3)" "unprognostic (2.44e-2)" "unprognostic (2.61e-1)" "unprognostic (1.96e-2)" "unprognostic (2.85e-3)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" "unprognostic (1.63e-3)" "unprognostic (8.44e-2)" "unprognostic (2.72e-1)" "unprognostic (5.59e-2)" "unprognostic (8.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" SLC26A7 SUT2 ENSG00000147606 "Solute carrier family 26 member 7" Q8TE54 8 91209494-91398155 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 320.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 9.7;Distal tubular cells: 15.4;Early spermatids: 12.6;Endometrial stromal cells: 18.9;Enteroendocrine cells: 21.1;Glandular and luminal cells: 45.5" "Group enriched" "Detected in some" 11 "renal cancer: 8.7;thyroid cancer: 32.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 11 "Rhabdoid: 21.4" "Kidney - Intercalated cells, Stomach - Parietal cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 11: White matter - Signal transduction" "Cluster 3: Rhabdoid - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (5.84e-2)" "unprognostic (8.04e-3)" "unprognostic (4.15e-3)" "unprognostic (1.51e-1)" "unprognostic (2.39e-3)" "unprognostic (2.94e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.41e-2)" "unprognostic (8.26e-2)" "unprognostic (4.82e-2)" "unprognostic (3.31e-2)" "unprognostic (2.07e-1)" "unprognostic (5.19e-3)" "unprognostic (6.83e-3)" SLC29A1 ENT1 ENSG00000112759 "Solute carrier family 29 member 1 (Augustine blood group)" Q99808 6 44219553-44234142 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 222.2;Extravillous trophoblasts: 243.5;Granulosa cells: 104.4;Oocytes: 224.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 26 "eosinophil: 1049.2" "Lineage enriched" "Detected in all" 26 "granulocytes: 1049.2" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012384 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA012384: AB_1857073" "unprognostic (1.82e-2)" "unprognostic (1.41e-2)" "unprognostic (1.81e-1)" "unprognostic (2.49e-3)" "unprognostic (2.76e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.96e-4)" "unprognostic (1.38e-2)" "unprognostic (4.60e-2)" "unprognostic (9.02e-2)" "unprognostic (1.34e-1)" SLC29A2 "DER12, ENT2, HNP36" ENSG00000174669 "Solute carrier family 29 member 2" Q14542 11 66362521-66372214 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 87.6;tongue: 45.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.9;Skeletal myocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018168 Approved NA Yes "Cluster 11: T-cells - Unknown function" "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA018168: AB_1857077" "unprognostic (3.20e-2)" "unprognostic (4.50e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.37e-1)" "unprognostic (5.08e-2)" "unprognostic (5.64e-2)" "unprognostic (1.60e-1)" "unprognostic (1.96e-1)" "unprognostic (2.09e-1)" "unprognostic (1.76e-1)" "unprognostic (5.28e-2)" "prognostic favorable (2.78e-4)" "unprognostic (2.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-1)" "unprognostic (6.38e-3)" SLC2A8 "GLUT8, GLUTX1" ENSG00000136856 "Solute carrier family 2 member 8" Q9NY64 9 127397138-127408424 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 133.1;Endometrial stromal cells: 85.5;Late spermatids: 317.3;Spermatocytes: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 76.1" "Lineage enriched" "Detected in all" 5 "dendritic cells: 76.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011935 Uncertain Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 44: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 32: Non-specific - Cell proliferation" "Cluster 9: Endometrial stromal cells - Transcription" Vesicles "HPA011935: AB_1849760" "unprognostic (6.49e-2)" "prognostic favorable (2.57e-6)" "unprognostic (9.13e-2)" "unprognostic (1.85e-3)" "unprognostic (4.23e-2)" "unprognostic (9.43e-3)" "unprognostic (2.62e-1)" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.36e-1)" "prognostic favorable (9.86e-6)" "unprognostic (1.70e-1)" "prognostic favorable (6.55e-6)" "unprognostic (4.25e-2)" "unprognostic (3.55e-1)" "unprognostic (1.59e-3)" "unprognostic (2.04e-3)" SLC30A1 "ZNT1, ZRC1" ENSG00000170385 "Solute carrier family 30 member 1" Q9Y6M5 1 211571568-211579161 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 83.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 83.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 79.1" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015275, HPA049000" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 83: Liver - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Glandular & Luminal cells - Unknown function" "Plasma membrane" Vesicles "HPA015275: AB_1857083, HPA049000: AB_2680593" "unprognostic (1.13e-1)" "unprognostic (2.67e-3)" "unprognostic (6.94e-2)" "unprognostic (1.81e-3)" "unprognostic (3.47e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-2)" "unprognostic (1.82e-3)" "unprognostic (4.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.42e-3)" "unprognostic (4.78e-2)" "unprognostic (2.23e-2)" "unprognostic (3.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (4.53e-2)" SLC30A10 "DKFZp547M236, ZnT-10, ZNT8, ZRC1" ENSG00000196660 "Solute carrier family 30 member 10" Q6XR72 1 219685427-219959018 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 23.8;liver: 33.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.5;Early spermatids: 52.3;Hepatocytes: 128.4;Late spermatids: 38.6;Proximal enterocytes: 43.3" "Cancer enriched" "Detected in some" 14 "liver cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.6" "Colon - Colon enterocytes, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064547 Enhanced NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" 3 "HPA064547: AB_2732715" "unprognostic (7.88e-2)" "unprognostic (1.07e-2)" "unprognostic (1.02e-1)" "unprognostic (7.25e-2)" "unprognostic (1.75e-2)" "unprognostic (3.74e-3)" "unprognostic (6.96e-2)" "unprognostic (3.72e-2)" "unprognostic (1.41e-1)" "unprognostic (1.95e-2)" "unprognostic (5.10e-2)" "unprognostic (3.10e-3)" "unprognostic (4.47e-7)" "unprognostic (3.16e-1)" "unprognostic (6.11e-2)" "unprognostic (6.19e-3)" "unprognostic (5.72e-2)" SLC30A2 ZNT2 ENSG00000158014 "Solute carrier family 30 member 2" Q9BRI3 1 26037252-26046118 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 96.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 29.9;Glandular and luminal cells: 93.9;Proximal tubular cells: 26.3;Syncytiotrophoblasts: 88.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 19.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA017979 Approved Vesicles NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 55 Vesicles "HPA017979: AB_1857085" "unprognostic (4.87e-2)" "unprognostic (6.70e-2)" "unprognostic (3.79e-2)" "unprognostic (1.79e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-2)" "unprognostic (2.25e-2)" "unprognostic (2.59e-1)" "unprognostic (3.67e-2)" "unprognostic (1.02e-1)" "unprognostic (6.99e-2)" "unprognostic (1.10e-1)" "prognostic favorable (2.86e-6)" "unprognostic (9.38e-2)" "unprognostic (3.50e-2)" "unprognostic (1.17e-1)" "unprognostic (3.01e-2)" SLC30A3 ZNT3 ENSG00000115194 "Solute carrier family 30 member 3" Q99726 2 27253684-27275817 "Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 28.8;epididymis: 66.8;testis: 34.2" "Cell type enhanced" "Detected in some" "Early spermatids: 15.6;Excitatory neurons: 15.1;Late spermatids: 34.3;Oocytes: 11.0;Peritubular cells: 10.4;Sertoli cells: 13.6;Spermatocytes: 12.8;Spermatogonia: 9.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 6.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Testis - Sertoli cells" "Group enriched" "Detected in all" 4 "amygdala: 130.8;basal ganglia: 48.2;cerebral cortex: 110.9;hippocampal formation: 69.1;white matter: 34.7" "Group enriched" "Detected in many" 7 "amygdala: 24.3;cerebral cortex: 72.0;hippocampal formation: 56.1" "HPA060505, HPA067637, CAB079044" Enhanced Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 63: Testis - Spermatid development" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 22 Vesicles "Nucleoplasm, Nucleoli, Cytosol" "CAB079044: , HPA060505: AB_2684296, HPA067637: AB_2685875" "unprognostic (2.05e-4)" "unprognostic (1.17e-1)" "unprognostic (6.84e-4)" "unprognostic (5.26e-2)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (1.43e-2)" "unprognostic (2.93e-2)" "unprognostic (2.64e-2)" "unprognostic (3.05e-1)" "unprognostic (2.20e-1)" "unprognostic (1.89e-1)" "unprognostic (4.65e-12)" "unprognostic (3.23e-2)" "unprognostic (1.76e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-4)" SLC30A4 ZNT4 ENSG00000104154 "Solute carrier family 30 member 4" O14863 15 45479606-45522755 "Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "prostate: 38.5" "Cell type enhanced" "Detected in many" "Early spermatids: 75.1;Late spermatids: 81.9;Prostatic glandular cells: 210.9;Spermatocytes: 44.3" "Cancer enriched" "Detected in all" 20 "prostate cancer: 34.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 9 "prostate cancer: 28.5" "Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 80: Non-specific - Endocytosis" "Cluster 34: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 14 "unprognostic (1.64e-2)" "unprognostic (1.40e-1)" "unprognostic (3.71e-1)" "unprognostic (9.49e-2)" "unprognostic (1.98e-1)" "unprognostic (3.29e-2)" "unprognostic (6.15e-2)" "unprognostic (9.74e-2)" "unprognostic (7.38e-3)" "unprognostic (1.51e-1)" "prognostic favorable (6.02e-4)" "unprognostic (2.66e-2)" "unprognostic (4.72e-3)" "unprognostic (1.29e-2)" "unprognostic (9.83e-2)" "unprognostic (8.28e-3)" "unprognostic (2.01e-3)" SLC30A6 "FLJ31101, ZNT6" ENSG00000152683 "Solute carrier family 30 member 6" Q6NXT4 2 32165841-32224379 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055032, HPA057328" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 49: Non-specific - Transcription" "Golgi apparatus" "HPA055032: AB_2682677, HPA057328: AB_2683411" "unprognostic (5.61e-2)" "unprognostic (9.11e-3)" "unprognostic (1.05e-3)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (2.98e-1)" "unprognostic (9.47e-2)" "unprognostic (1.88e-1)" "unprognostic (3.30e-3)" "unprognostic (7.05e-2)" "unprognostic (3.06e-2)" "unprognostic (3.51e-1)" "unprognostic (3.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.90e-1)" SLC30A8 "ZnT-8, ZNT8" ENSG00000164756 "Solute carrier family 30 member 8" Q8IWU4 8 116950273-117176714 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport, Zinc transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 50.7" "Cell type enriched" "Detected in some" 20 "Pancreatic endocrine cells: 140.9" "Group enriched" "Detected in some" 28 "breast cancer: 10.6;pancreatic cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 18.5;Sarcoma: 16.7" "Kidney - Proximal tubular cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 5.5" "HPA065953, HPA076165" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" 66 "Vesicles, Plasma membrane" "HPA065953: , HPA076165: AB_2732304" "unprognostic (2.14e-2)" "unprognostic (1.48e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.57e-2)" "unprognostic (4.38e-1)" "unprognostic (3.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.66e-2)" "unprognostic (6.51e-3)" "unprognostic (2.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (9.16e-3)" SLC33A1 "ACATN, AT-1, AT1, SPG42" ENSG00000169359 "Solute carrier family 33 member 1" O00400 3 155821024-155854456 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Cataract, Deafness, Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042430 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 1 "Vesicles, Cytosol" "HPA042430: AB_10806238" "unprognostic (5.12e-3)" "unprognostic (7.78e-2)" "unprognostic (1.13e-2)" "unprognostic (7.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.34e-1)" "unprognostic (2.73e-2)" "unprognostic (9.57e-2)" "unprognostic (5.65e-2)" "unprognostic (6.61e-2)" "unprognostic (4.36e-2)" "unprognostic (1.19e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-2)" "unprognostic (2.92e-1)" "unprognostic (4.73e-2)" "unprognostic (5.74e-2)" SLC35A1 "CMPST, hCST" ENSG00000164414 "Solute carrier family 35 member A1" P78382 6 87470623-87512336 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 99.5;Inhibitory neurons: 83.6;Intestinal goblet cells: 77.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Intestine - Digestion" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" 27 "unprognostic (3.04e-2)" "unprognostic (1.93e-1)" "unprognostic (6.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.82e-1)" "unprognostic (4.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (1.58e-2)" "unprognostic (3.01e-3)" "unprognostic (7.26e-2)" "unprognostic (3.85e-1)" "prognostic unfavorable (2.70e-6)" "unprognostic (2.85e-1)" "unprognostic (8.51e-2)" "unprognostic (5.48e-2)" "unprognostic (1.04e-1)" SLC35A3 ENSG00000117620 "Solute carrier family 35 member A3" Q9Y2D2 1 99969351-100035634 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Sugar transport, Transport" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 188.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Gallbladder cancer: 118.3" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015253 Uncertain NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA015253: AB_1857106" "unprognostic (1.05e-1)" "unprognostic (2.69e-1)" "unprognostic (1.57e-3)" "unprognostic (5.89e-2)" "unprognostic (9.64e-2)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (4.02e-2)" "unprognostic (2.59e-2)" "unprognostic (1.47e-1)" "unprognostic (1.76e-3)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-3)" "unprognostic (2.32e-1)" "unprognostic (2.73e-2)" "unprognostic (9.34e-2)" SLC35B4 "FLJ14697, YEA4" ENSG00000205060 "Solute carrier family 35 member B4" Q969S0 7 134289332-134316930 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 97.9;Syncytiotrophoblasts: 88.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049779 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 28: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 24: Cytotrophoblasts - Mitochondria" 25 "HPA049779: AB_2680878" "unprognostic (1.84e-1)" "unprognostic (1.94e-2)" "unprognostic (7.19e-2)" "unprognostic (2.49e-2)" "unprognostic (1.77e-3)" "unprognostic (3.47e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (1.57e-1)" "unprognostic (3.32e-2)" "unprognostic (6.88e-3)" "unprognostic (1.86e-1)" "unprognostic (2.24e-3)" "unprognostic (3.18e-2)" "unprognostic (2.86e-1)" "unprognostic (9.81e-2)" "unprognostic (1.00e-1)" SLC35D2 "SQV7L, UGTrel8" ENSG00000130958 "Solute carrier family 35 member D2" Q76EJ3 9 96313444-96383711 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 109.0;Proximal enterocytes: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skin - Endothelial cells, Stomach - Gastric mucous cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA064047 Approved Supported "Golgi apparatus" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 5: Enterocytes - Absorption" "Golgi apparatus" "HPA064047: AB_2685182" "unprognostic (3.67e-1)" "unprognostic (5.73e-2)" "unprognostic (2.59e-1)" "unprognostic (1.16e-2)" "unprognostic (3.17e-1)" "unprognostic (8.86e-3)" "unprognostic (4.25e-3)" "unprognostic (2.24e-2)" "unprognostic (4.12e-1)" "unprognostic (5.67e-2)" "unprognostic (1.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.74e-2)" "unprognostic (1.33e-2)" "unprognostic (2.04e-1)" "unprognostic (1.99e-2)" "unprognostic (1.44e-1)" SLC36A4 "FLJ38932, PAT4" ENSG00000180773 "Solute carrier family 36 member 4" Q6YBV0 11 93144174-93197991 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017887 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus, Plasma membrane, Cytosol" "HPA017887: AB_2190238" "unprognostic (1.23e-2)" "unprognostic (1.08e-1)" "unprognostic (2.17e-3)" "unprognostic (1.32e-3)" "unprognostic (3.66e-2)" "unprognostic (8.77e-2)" "unprognostic (1.08e-3)" "unprognostic (7.83e-3)" "unprognostic (3.06e-2)" "unprognostic (7.97e-2)" "unprognostic (2.09e-2)" "unprognostic (8.04e-3)" "unprognostic (7.07e-2)" "unprognostic (4.40e-2)" "unprognostic (1.74e-1)" "unprognostic (9.45e-3)" "unprognostic (4.20e-2)" SLC37A3 "DKFZp761N0624, SPX3" ENSG00000157800 "Solute carrier family 37 member 3" Q8NCC5 7 140293693-140404433 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 9: Endometrial stromal cells - Transcription" "unprognostic (2.39e-1)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.44e-1)" "unprognostic (5.59e-2)" "unprognostic (2.69e-2)" "unprognostic (2.35e-1)" "prognostic unfavorable (4.78e-5)" "unprognostic (1.97e-1)" "unprognostic (2.94e-1)" "unprognostic (3.78e-2)" "unprognostic (2.84e-2)" "unprognostic (1.54e-1)" "unprognostic (2.16e-2)" "unprognostic (3.31e-1)" "unprognostic (3.82e-1)" "unprognostic (1.49e-1)" "unprognostic (5.50e-2)" SLC38A6 NAT-1 ENSG00000139974 "Solute carrier family 38 member 6" Q8IZM9 14 60981114-61114316 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 213.7;Excitatory neurons: 95.5;Hofbauer cells: 91.0;Inhibitory neurons: 74.3;Late spermatids: 120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018508 Approved Approved "Plasma membrane,Cell Junctions,Microtubules" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 51: Thyroid gland - Unknown function" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 34: Neurons - Neuronal signaling" "Cell Junctions" "Plasma membrane, Microtubules" "HPA018508: AB_2190518" "unprognostic (7.08e-2)" "unprognostic (4.14e-2)" "unprognostic (1.75e-1)" "unprognostic (3.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (9.47e-6)" "unprognostic (9.89e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-2)" "unprognostic (2.20e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (1.37e-5)" "unprognostic (1.73e-1)" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-1)" SLC38A8 ENSG00000166558 "Solute carrier family 38 member 8" A6NNN8 16 84009667-84042795 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.7" "Cell type enriched" "Detected in some" 10 "Oocytes: 169.8" "Cancer enriched" "Detected in single" 14 "melanoma: 6.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.0" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 44: Oocytes - Unknown function" "unprognostic (9.69e-2)" "unprognostic (6.16e-2)" "unprognostic (8.00e-3)" "unprognostic (6.40e-2)" "unprognostic (1.03e-1)" "unprognostic (8.20e-3)" "unprognostic (1.89e-1)" "unprognostic (7.70e-2)" "unprognostic (2.59e-1)" "unprognostic (2.16e-2)" "unprognostic (3.54e-2)" "unprognostic (1.37e-1)" "unprognostic (1.45e-1)" SLC39A10 "DKFZp564L2123, FLJ90515, KIAA1265" ENSG00000196950 "Solute carrier family 39 member 10" Q9ULF5 2 195575977-195737702 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.6;thyroid gland: 47.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 165.1;Microglial cells: 346.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036512, HPA036513, HPA066087" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 250000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036512: AB_2675165, HPA036513: AB_10670801, HPA066087: AB_2685613" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (5.33e-2)" "unprognostic (1.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (7.40e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (2.10e-2)" "unprognostic (8.73e-2)" "unprognostic (2.84e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (8.46e-2)" "unprognostic (9.71e-2)" "unprognostic (1.34e-2)" "unprognostic (3.68e-1)" "unprognostic (2.47e-2)" "unprognostic (6.89e-2)" SLC39A13 FLJ25785 ENSG00000165915 "Solute carrier family 39 member 13" Q96H72 11 47407132-47416496 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 939.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043971 Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Late spermatids - Unknown function" 4 "HPA043971: AB_10959744" "unprognostic (7.84e-2)" "unprognostic (1.02e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (1.18e-1)" "unprognostic (8.56e-3)" "unprognostic (3.81e-2)" "unprognostic (7.44e-3)" "unprognostic (1.36e-1)" "unprognostic (5.40e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (1.39e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.96e-4)" "unprognostic (3.16e-1)" "unprognostic (1.73e-1)" "unprognostic (8.61e-2)" "unprognostic (4.12e-1)" SLC39A14 "KIAA0062, NET34, ZIP14" ENSG00000104635 "Solute carrier family 39 member 14" Q15043 8 22367278-22434129 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 537.7;pancreas: 245.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 255.4;Hepatocytes: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016508, HPA056732" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA 1100000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "HPA016508: AB_1857148, HPA056732: " "unprognostic (1.67e-1)" "unprognostic (6.67e-3)" "prognostic favorable (5.00e-5)" "unprognostic (9.83e-3)" "unprognostic (9.21e-3)" "unprognostic (8.99e-3)" "unprognostic (1.99e-1)" "unprognostic (2.91e-2)" "unprognostic (4.95e-2)" "unprognostic (5.66e-2)" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.79e-7)" "unprognostic (4.88e-2)" "unprognostic (8.73e-2)" "unprognostic (1.63e-2)" "unprognostic (1.11e-3)" SLC39A4 "AEZ, AWMS2, ZIP4" ENSG00000147804 "Solute carrier family 39 member 4" Q6P5W5 8 144409742-144416844 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 85.4" "Cell type enhanced" "Detected in many" "Oocytes: 258.8;Proximal enterocytes: 393.6;Proximal tubular cells: 231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (2.59e-1)" "unprognostic (2.35e-3)" "unprognostic (9.16e-2)" "unprognostic (3.84e-2)" "unprognostic (5.63e-3)" "unprognostic (1.46e-1)" "unprognostic (5.40e-2)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (3.28e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "prognostic favorable (9.04e-4)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (9.04e-3)" "unprognostic (1.87e-1)" SLC39A5 ENSG00000139540 "Solute carrier family 39 member 5" Q6ZMH5 12 56230049-56237846 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "intestine: 230.5;kidney: 105.8;liver: 167.0;pancreas: 297.9" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 802.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 30.6;liver cancer: 36.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "colorectal cancer: 20.4;Gastric cancer: 12.0;liver cancer: 22.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA018423 Approved Nucleoplasm,Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" Vesicles Nucleoplasm "HPA018423: AB_1857154" "unprognostic (5.94e-3)" "unprognostic (8.29e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-7)" "unprognostic (1.73e-1)" "unprognostic (7.79e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.93e-3)" "prognostic favorable (5.05e-4)" "unprognostic (2.75e-1)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.96e-4)" SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 272.5;Prostatic glandular cells: 438.2" "Group enriched" "Detected in all" 4 "breast cancer: 361.9;prostate cancer: 127.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 53: Non-specific - Glycosylation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Breast glandular cells - Lactation" Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: AB_2677968" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (5.50e-3)" "unprognostic (2.58e-3)" "unprognostic (1.02e-1)" "unprognostic (4.87e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-1)" "unprognostic (4.50e-2)" "unprognostic (7.63e-3)" "unprognostic (2.16e-1)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" SLC39A7 "D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7" ENSG00000112473 "Solute carrier family 39 member 7" Q92504 6 33200305-33204439 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 185.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053999 Approved Supported "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 68: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 77: Plasma cells - Protein processing" 24 "Endoplasmic reticulum" Nucleoplasm "HPA053999: AB_2682338" "unprognostic (3.63e-2)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (3.24e-2)" "unprognostic (8.95e-2)" "unprognostic (2.51e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (4.87e-2)" "unprognostic (9.92e-2)" "unprognostic (7.20e-3)" "unprognostic (3.29e-1)" "unprognostic (2.40e-1)" "unprognostic (1.99e-2)" "unprognostic (4.80e-1)" "unprognostic (1.50e-1)" "unprognostic (8.22e-3)" "unprognostic (1.12e-2)" SLC39A8 BIGM103 ENSG00000138821 "Solute carrier family 39 member 8" Q9C0K1 4 102251080-102431258 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Symport, Transport, Zinc transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 67.8" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 735.2;Alveolar cells type 2: 629.7;Extravillous trophoblasts: 241.4;Mesothelial cells: 581.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038832, HPA038833" Approved NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Protein processing" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Alveolar cells - Lung function" "HPA038832: AB_2676226, HPA038833: AB_10670910" "prognostic favorable (6.69e-4)" "unprognostic (1.29e-2)" "prognostic favorable (1.34e-4)" "unprognostic (1.91e-2)" "unprognostic (6.50e-2)" "unprognostic (9.59e-2)" "unprognostic (6.07e-2)" "unprognostic (2.74e-1)" "unprognostic (1.20e-3)" "unprognostic (6.32e-2)" "unprognostic (5.46e-3)" "unprognostic (2.78e-2)" "prognostic favorable (6.34e-6)" "unprognostic (3.25e-1)" "unprognostic (6.54e-2)" "unprognostic (6.40e-2)" "unprognostic (7.13e-3)" SLC39A9 FLJ11274 ENSG00000029364 "Solute carrier family 39 member 9" Q9NUM3 14 69398015-69462390 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007921, HPA075390" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 75: Serous glandular cells - Salivary secretion" 30 "Endoplasmic reticulum" "HPA007921: AB_1080007, HPA075390: AB_2686748" "unprognostic (2.37e-1)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (4.35e-2)" "unprognostic (1.10e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-1)" "unprognostic (2.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.20e-1)" "unprognostic (1.83e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" SLC43A1 "PB39, POV1, R00504" ENSG00000149150 "Solute carrier family 43 member 1" O75387 11 57484534-57515780 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 125.5;pancreas: 225.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.4;Erythroid cells: 49.2;Exocrine glandular cells: 34.2;Hepatocytes: 104.9" "Cancer enhanced" "Detected in all" "liver cancer: 45.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018813, HPA018826" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Protein processing" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 1: Erythroid cells - Oxygen transport" 1 "Golgi apparatus, Vesicles, Plasma membrane" "HPA018813: AB_1857164, HPA018826: AB_1857165" "unprognostic (3.04e-1)" "unprognostic (1.15e-1)" "unprognostic (9.19e-2)" "prognostic favorable (3.19e-4)" "unprognostic (2.51e-2)" "unprognostic (5.48e-2)" "unprognostic (2.32e-1)" "unprognostic (6.71e-3)" "unprognostic (1.63e-1)" "unprognostic (3.12e-2)" "unprognostic (6.06e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (2.97e-5)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (7.30e-2)" SLC46A1 "HCP1, hPCFT, HsPCFT, MGC9564, PCFT" ENSG00000076351 "Solute carrier family 46 member 1" Q96NT5 17 28394642-28407197 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 91.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 22.3;Hepatocytes: 26.0;Hofbauer cells: 22.9;Kupffer cells: 23.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011614 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "CAB011614: AB_2270597" "unprognostic (1.10e-1)" "unprognostic (8.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (9.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (3.80e-2)" "unprognostic (1.04e-3)" "unprognostic (6.15e-2)" "unprognostic (2.10e-3)" "unprognostic (2.16e-1)" "unprognostic (2.94e-1)" "unprognostic (2.15e-1)" "unprognostic (1.04e-1)" SLC47A1 "FLJ10847, MATE1" ENSG00000142494 "Solute carrier family 47 member 1" Q96FL8 17 19495385-19579034 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 123.4;kidney: 96.7;liver: 100.6" "Cell type enhanced" "Detected in many" "Early spermatids: 17.9;Hepatocytes: 36.9;Inhibitory neurons: 13.8;Proximal tubular cells: 38.7;Skeletal myocytes: 30.2" "Cancer enhanced" "Detected in many" "renal cancer: 37.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 12.2;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 6 "dendritic cells: 6.6;granulocytes: 12.2" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021987 Enhanced NA NA 18000 "Cluster 29: Non-specific - Unknown function" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Proximal tubular cells - Transmembrane transport" 1 "HPA021987: AB_1857185" "unprognostic (1.17e-2)" "unprognostic (1.94e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.54e-8)" "unprognostic (7.87e-2)" "unprognostic (8.34e-2)" "unprognostic (2.92e-2)" "prognostic favorable (1.88e-5)" "unprognostic (4.84e-2)" "unprognostic (6.89e-2)" "unprognostic (6.75e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.06e-5)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.91e-2)" "unprognostic (9.40e-2)" SLC49A3 "FLJ22269, LP2561, MFSD7" ENSG00000169026 "Solute carrier family 49 member 3" Q6UXD7 4 681829-689271 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 36.8;Extravillous trophoblasts: 39.0;Hofbauer cells: 34.2;Late spermatids: 36.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043593 Uncertain NA NA "Cluster 21: Testis - Unknown function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" "HPA043593: AB_10959611" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (8.77e-2)" "unprognostic (4.70e-2)" "unprognostic (9.40e-2)" "unprognostic (1.84e-3)" "unprognostic (2.22e-1)" "unprognostic (1.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.56e-1)" "unprognostic (9.22e-2)" "unprognostic (2.08e-1)" "prognostic favorable (2.66e-5)" "unprognostic (8.35e-2)" "unprognostic (4.92e-2)" "unprognostic (7.48e-2)" "unprognostic (1.11e-1)" SLC4A8 NBC3 ENSG00000050438 "Solute carrier family 4 member 8" Q2Y0W8 12 51391317-51515763 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 12.6;pituitary gland: 17.4;retina: 10.8;testis: 11.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.2;Cone photoreceptor cells: 62.9;Early spermatids: 56.8;Excitatory neurons: 111.0;Horizontal cells: 107.0;Inhibitory neurons: 122.7;Oligodendrocytes: 231.8;Spermatocytes: 86.3" "Group enriched" "Detected in some" 6 "breast cancer: 1.7;glioma: 2.7;testis cancer: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 24.4" "Lung - Respiratory ciliated cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077895 Approved "Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 28: Neuronal - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane" "HPA077895: " "unprognostic (4.01e-1)" "unprognostic (8.15e-2)" "unprognostic (2.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.96e-2)" "unprognostic (3.46e-2)" "unprognostic (7.72e-4)" "unprognostic (3.13e-2)" "unprognostic (7.03e-3)" "unprognostic (1.07e-4)" "unprognostic (1.70e-1)" "unprognostic (9.60e-6)" "unprognostic (1.35e-1)" "unprognostic (2.57e-1)" "unprognostic (3.21e-2)" "unprognostic (2.47e-1)" SLC66A1 "FLJ20320, LAAT-1, LAAT1, PQLC2" ENSG00000040487 "Solute carrier family 66 member 1" Q6ZP29 1 19312326-19329300 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 33.2;Syncytiotrophoblasts: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057810 Approved Supported Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 27: Syncytiotrophoblasts - Pregnancy" Vesicles "HPA057810: AB_2683535" "unprognostic (7.84e-3)" "unprognostic (6.56e-2)" "unprognostic (6.54e-2)" "prognostic favorable (3.50e-4)" "unprognostic (3.77e-3)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.64e-5)" "unprognostic (2.61e-1)" "unprognostic (4.47e-2)" "unprognostic (1.04e-1)" "unprognostic (1.42e-3)" "unprognostic (3.82e-2)" "unprognostic (4.70e-3)" "unprognostic (8.64e-2)" "unprognostic (2.07e-1)" "unprognostic (6.56e-2)" "unprognostic (4.46e-2)" SLC66A2 "FLJ22378, PQLC1" ENSG00000122490 "Solute carrier family 66 member 2" Q8N2U9 18 79902420-79951657 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 180.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 153.5;Late spermatids: 175.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051666 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 83: Liver - Metabolism" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 28: Dendritic cells - Antigen presentation" 19 Nucleoplasm "HPA051666: AB_2681567" "unprognostic (6.03e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (6.45e-2)" "unprognostic (3.94e-2)" "unprognostic (2.07e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" "unprognostic (4.34e-1)" "unprognostic (1.40e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.70e-2)" SLC6A15 "FLJ10316, hv7-3, NTT73, SBAT1, V7-3" ENSG00000072041 "Solute carrier family 6 member 15" Q9H2J7 12 84859491-84913629 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Neurotransmitter transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.6;retina: 15.2" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 27.3;Bipolar cells: 35.0;Excitatory neurons: 61.7;Horizontal cells: 39.0;Inhibitory neurons: 54.9;Melanocytes: 73.9;Oligodendrocytes: 43.6;Rod photoreceptor cells: 28.1" "Group enriched" "Detected in some" 4 "head and neck cancer: 2.2;melanoma: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 38.9;skin cancer: 33.3" "Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008609 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 5 Nucleoli Vesicles "HPA008609: AB_1857190" "unprognostic (1.01e-4)" "unprognostic (9.02e-2)" "unprognostic (1.27e-1)" "unprognostic (6.65e-6)" "unprognostic (1.25e-2)" "unprognostic (2.92e-1)" "unprognostic (7.65e-3)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (1.51e-1)" "unprognostic (4.05e-2)" "unprognostic (7.69e-4)" "unprognostic (2.57e-2)" "unprognostic (3.80e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-3)" SLC7A5 "CD98, D16S469E, E16, LAT1, MPE16" ENSG00000103257 "Solute carrier family 7 member 5" Q01650 16 87830023-87869507 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 109.2;esophagus: 97.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 163.8;dendritic cells: 327.8;Plasma cells: 133.2;Syncytiotrophoblasts: 132.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 17.2" "Lineage enriched" "Detected in many" 10 "dendritic cells: 17.2" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1339.5" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052673, HPA056077" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 51000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Dendritic cells - Antigen presentation" 1 "Plasma membrane, Cytosol" Vesicles "HPA052673: AB_2681909, HPA056077: AB_2683031" "unprognostic (2.71e-3)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-1)" "unprognostic (3.22e-2)" "unprognostic (2.99e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (6.86e-2)" "unprognostic (4.46e-2)" "unprognostic (1.27e-1)" "unprognostic (3.17e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.93e-2)" "unprognostic (5.52e-3)" "unprognostic (1.64e-2)" "unprognostic (7.19e-3)" SLC7A7 "LPI, y+LAT-1" ENSG00000155465 "Solute carrier family 7 member 7" Q9UM01 14 22773222-22829820 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 117.6;kidney: 261.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 247.6;Kupffer cells: 327.7;Macrophages: 131.4;monocytes: 264.1;Proximal enterocytes: 399.8;Proximal tubular cells: 264.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 393.7;non-classical monocyte: 447.3" "Lineage enriched" "Detected in many" 5 "monocytes: 447.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036227 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 52: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Proximal enterocytes - Digestion" "HPA036227: AB_10696653" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (4.25e-2)" "unprognostic (2.52e-1)" "unprognostic (6.12e-2)" "unprognostic (3.69e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (2.88e-2)" "unprognostic (1.73e-2)" "unprognostic (2.60e-3)" "unprognostic (7.15e-2)" "prognostic unfavorable (6.28e-6)" "unprognostic (2.68e-3)" "unprognostic (1.86e-2)" "unprognostic (2.61e-1)" "unprognostic (1.12e-1)" SLC7A8 "LAT2, LPI-PC1" ENSG00000092068 "Solute carrier family 7 member 8" Q9UHI5 14 23125295-23183674 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 319.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 98.0;Proximal tubular cells: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 8.3;eosinophil: 11.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.8" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046015, HPA051950, HPA060672" Enhanced NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 3: Basal prostatic cells - Lipid metabolism" 25 "CAB046015: AB_2239464, HPA051950: AB_2681670, HPA060672: AB_2684340" "unprognostic (1.50e-1)" "unprognostic (1.52e-1)" "unprognostic (2.88e-1)" "unprognostic (1.03e-2)" "unprognostic (1.12e-2)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.97e-4)" "prognostic favorable (3.15e-4)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (1.39e-3)" "unprognostic (9.44e-2)" "unprognostic (7.00e-2)" "unprognostic (2.96e-2)" "unprognostic (8.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.52e-4)" SLC9B1 "NHA1, NHEDC1" ENSG00000164037 "Solute carrier family 9 member B1" Q4ZJI4 4 102885048-103019719 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Fertilization, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "testis: 39.2" "Group enriched" "Detected in many" 4 "Early spermatids: 201.1;Late spermatids: 97.5;Spermatocytes: 170.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058971, HPA065520" Supported "Centriolar satellite,Mitochondria" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" Mitochondria "Centriolar satellite" "HPA058971: AB_2683865, HPA065520: AB_2685502" "unprognostic (4.87e-3)" "unprognostic (2.38e-1)" "unprognostic (1.18e-1)" "unprognostic (8.26e-4)" "unprognostic (2.53e-1)" "unprognostic (3.39e-1)" "unprognostic (5.06e-4)" "unprognostic (5.85e-2)" "unprognostic (1.35e-1)" "unprognostic (1.54e-1)" "unprognostic (1.07e-3)" "unprognostic (7.68e-2)" "unprognostic (3.03e-2)" "unprognostic (3.33e-1)" "unprognostic (1.85e-1)" "unprognostic (5.66e-5)" "unprognostic (5.78e-2)" SLC9B2 "FLJ23984, NHA2, NHEDC2" ENSG00000164038 "Solute carrier family 9 member B2" Q86UD5 4 103019868-103085829 "Predicted membrane proteins, Transporters" "Antiport, Hydrogen ion transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 37.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 55.9;Exocrine glandular cells: 34.6;Hepatocytes: 37.3;Inhibitory neurons: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.9" "Group enriched" "Detected in many" 5 "B-cells: 5.1;NK-cells: 11.9;T-cells: 6.4" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047008 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Liver - Oxidoreductase activity" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 45: Non-specific - Mixed function" 1 "Nucleoplasm, Cell Junctions" "HPA047008: AB_2679901" "unprognostic (1.85e-1)" "unprognostic (5.43e-2)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.43e-2)" "unprognostic (3.78e-2)" "unprognostic (3.26e-1)" "unprognostic (2.53e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-5)" "unprognostic (2.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-2)" "unprognostic (2.35e-5)" SPNS1 "HSpin1, LAT, nrs, PP2030, SLC63A1, SPIN1, SPINL" ENSG00000169682 "Sphingolipid transporter 1 (putative)" Q9H2V7 16 28974221-28984548 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041995, HPA042988" Enhanced Approved "Nucleoli fibrillar center,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 49: Non-specific - Transcription" 2 Vesicles "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA041995: AB_10959609, HPA042988: AB_10964587" "unprognostic (3.54e-2)" "unprognostic (4.57e-4)" "unprognostic (2.15e-1)" "unprognostic (2.49e-1)" "unprognostic (2.08e-1)" "unprognostic (3.66e-1)" "unprognostic (7.86e-5)" "unprognostic (1.01e-1)" "unprognostic (2.00e-1)" "unprognostic (1.27e-1)" "unprognostic (4.12e-2)" "unprognostic (3.02e-3)" "unprognostic (8.85e-7)" "unprognostic (1.48e-1)" "unprognostic (6.15e-2)" "unprognostic (1.26e-3)" "unprognostic (1.12e-2)" SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 178.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 16: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 12: Squamous epithelial cells - Keratinization" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" STEAP1 "PRSS24, STEAP" ENSG00000164647 "STEAP family member 1" Q9UHE8 7 90154456-90164829 "Cancer-related genes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 81.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 148.3;Club cells: 62.9;Ionocytes: 146.2;Mesothelial cells: 87.3;Prostatic glandular cells: 180.1" "Cancer enriched" "Detected in all" 6 "prostate cancer: 94.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 177.2" "Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" HPA030985 Uncertain NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "HPA030985: AB_2673686" "unprognostic (2.88e-3)" "unprognostic (2.29e-1)" "unprognostic (1.19e-1)" "unprognostic (3.21e-3)" "unprognostic (9.20e-3)" "unprognostic (2.03e-1)" "unprognostic (1.33e-2)" "unprognostic (6.74e-3)" "unprognostic (6.36e-2)" "unprognostic (6.45e-3)" "unprognostic (8.31e-3)" "unprognostic (3.79e-1)" "unprognostic (2.60e-2)" "unprognostic (4.39e-2)" "unprognostic (2.42e-1)" "unprognostic (6.09e-2)" "unprognostic (1.38e-1)" STEAP2 "IPCA-1, PCANAP1, STAMP1, STMP" ENSG00000157214 "STEAP2 metalloreductase" Q8NFT2 7 90167590-90238137 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "prostate: 123.5" "Cell type enriched" "Detected in many" 9 "Prostatic glandular cells: 640.5" "Cancer enriched" "Detected in many" 12 "prostate cancer: 88.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 90.6" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029115, HPA055603" Uncertain Supported Vesicles NA NA "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" Vesicles "HPA029115: AB_10603894, HPA055603: " "unprognostic (6.26e-3)" "unprognostic (2.48e-1)" "unprognostic (2.55e-1)" "unprognostic (1.65e-1)" "unprognostic (8.20e-4)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (3.67e-3)" "unprognostic (7.91e-2)" "unprognostic (1.70e-1)" "unprognostic (9.92e-2)" "unprognostic (1.34e-1)" "unprognostic (2.71e-2)" "unprognostic (9.73e-2)" "unprognostic (6.11e-2)" "unprognostic (9.86e-5)" "unprognostic (3.69e-2)" STEAP3 "dudlin-2, STMP3, TSAP6" ENSG00000115107 "STEAP3 metalloreductase" Q658P3 2 119223831-119265652 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 184.9;parathyroid gland: 76.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 75.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.4;intermediate monocyte: 2.7;myeloid DC: 4.1;NK-cell: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 4.1;monocytes: 2.7;NK-cells: 1.3" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050510 Approved Approved Nucleoli,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Hepatocytes - Metabolism" 1 Cytosol Nucleoli "HPA050510: AB_2681151" "unprognostic (6.51e-2)" "unprognostic (6.48e-2)" "unprognostic (4.89e-2)" "unprognostic (3.45e-2)" "unprognostic (1.94e-3)" "unprognostic (9.07e-2)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (9.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.08e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.82e-1)" "unprognostic (4.45e-1)" "unprognostic (9.37e-2)" "unprognostic (6.82e-2)" STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 109.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 161.5;Club cells: 154.6;Ionocytes: 97.6;Leydig cells: 114.1;Mucus glandular cells: 120.2;Sertoli cells: 204.0;Smooth muscle cells: 296.6" "Cancer enhanced" "Detected in many" "prostate cancer: 45.9" "Region enriched" "Detected in all" 4 "choroid plexus: 39.4" "Immune cell enriched" "Detected in some" 12 "neutrophil: 161.9" "Lineage enriched" "Detected in many" 12 "granulocytes: 161.9" "Cancer enriched" "Detected in many" 6 "cervical cancer: 90.3" "Breast - Endothelial cells, Colon - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Smooth muscle cells - Signal transduction" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "prognostic favorable (2.97e-4)" "unprognostic (7.40e-2)" "unprognostic (3.12e-1)" "unprognostic (4.66e-2)" "unprognostic (4.21e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (4.53e-2)" SVOPL MGC46715 ENSG00000157703 "SVOP like" Q8N434 7 138594285-138701362 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.8" "Group enriched" "Detected in some" 5 "granulocytes: 32.8;Oocytes: 61.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 14 "eosinophil: 2.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.1" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA018035 Uncertain NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Granulocytes - Unknown function" "HPA018035: AB_2197028" "unprognostic (6.70e-5)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (2.49e-1)" "unprognostic (5.24e-2)" "unprognostic (2.38e-1)" "unprognostic (7.69e-3)" "unprognostic (2.59e-3)" "unprognostic (7.16e-2)" "unprognostic (1.64e-1)" "unprognostic (4.46e-3)" "unprognostic (5.03e-3)" "unprognostic (2.22e-4)" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (1.51e-1)" "unprognostic (8.51e-2)" TAP2 "ABCB3, D6S217E, PSF2, RING11" ENSG00000204267 "Transporter 2, ATP binding cassette subfamily B member" Q03519 6 32821833-32838739 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Peptide transport, Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001312 Approved Supported "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 14: Langerhans cells - Innate immune response" 2 "Endoplasmic reticulum" "Nuclear speckles" "HPA001312: AB_1080206" "unprognostic (2.95e-3)" "unprognostic (2.35e-1)" "unprognostic (3.77e-2)" "unprognostic (1.12e-1)" "unprognostic (1.39e-1)" "unprognostic (3.46e-1)" "unprognostic (8.04e-2)" "unprognostic (1.28e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-2)" "prognostic unfavorable (1.51e-4)" "unprognostic (1.90e-1)" "prognostic unfavorable (5.22e-8)" "unprognostic (5.32e-1)" "unprognostic (4.17e-2)" "unprognostic (2.35e-1)" "unprognostic (4.71e-2)" TAPT1 FLJ90013 ENSG00000169762 "Transmembrane anterior posterior transformation 1" Q6NXT6 4 16160505-16227410 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Chondrogenesis, Cilium biogenesis/degradation, Differentiation, Host-virus interaction, Osteogenesis" "Developmental protein, Receptor" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 146.1;Late spermatids: 176.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042567 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 66: Photoreceptor cells - Visual perception" Centrosome "Nucleoplasm, Cytosol" "HPA042567: AB_2678055" "unprognostic (2.34e-1)" "unprognostic (5.84e-2)" "unprognostic (1.41e-2)" "prognostic favorable (9.75e-4)" "unprognostic (2.43e-1)" "unprognostic (2.56e-2)" "unprognostic (2.32e-3)" "unprognostic (3.15e-3)" "unprognostic (1.54e-1)" "unprognostic (6.30e-2)" "prognostic favorable (5.34e-4)" "unprognostic (7.07e-2)" "prognostic favorable (8.52e-4)" "unprognostic (9.00e-2)" "unprognostic (8.52e-2)" "unprognostic (7.25e-3)" "prognostic favorable (4.18e-4)" TEDDM1 "EDDM9, Epdd1, HE9, TMEM45C" ENSG00000203730 "Transmembrane epididymal protein 1" Q5T9Z0 1 182398117-182400667 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 534 "epididymis: 562.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 15: Non-specific - Transcription" "Cluster 10: Muller glia cells - Visual perception" "unprognostic (4.21e-2)" "unprognostic (8.89e-2)" "unprognostic (2.18e-1)" "unprognostic (4.22e-2)" "unprognostic (6.71e-4)" "unprognostic (4.43e-3)" "unprognostic (2.86e-2)" "unprognostic (4.57e-2)" "unprognostic (4.20e-1)" "unprognostic (7.22e-3)" "unprognostic (1.23e-1)" "unprognostic (3.39e-2)" "unprognostic (2.47e-2)" "unprognostic (6.99e-3)" TLCD4-RWDD3 TMEM56-RWDD3 ENSG00000271092 "TLCD4-RWDD3 readthrough" 1 95117923-95247225 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Erythroid cells: 4.2;Excitatory neurons: 3.6;Inhibitory neurons: 4.3;Oligodendrocyte precursor cells: 5.7;Oligodendrocytes: 3.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" NA NA "Cluster 83: Liver - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 76: Oligodendrocyte precursor - Unknown function" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (9.43e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.77e-3)" "unprognostic (4.35e-2)" "unprognostic (7.05e-2)" "unprognostic (1.70e-1)" "unprognostic (4.00e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.29e-2)" "unprognostic (3.42e-1)" "unprognostic (2.72e-1)" "unprognostic (1.99e-1)" "unprognostic (1.42e-2)" TLCD5 "MGC17839, TMEM136" ENSG00000181264 "TLC domain containing 5" Q6ZRR5 11 120325296-120333686 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 50.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 88.4;Rod photoreceptor cells: 87.4;Sertoli cells: 49.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.2" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.2" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074432 Approved Vesicles,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 66: Photoreceptor cells - Visual perception" Vesicles Cytosol "HPA074432: AB_2686689" "unprognostic (1.02e-1)" "unprognostic (6.56e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (1.65e-2)" "unprognostic (3.31e-2)" "unprognostic (6.81e-3)" "unprognostic (1.22e-1)" "unprognostic (1.39e-2)" "unprognostic (2.58e-1)" "unprognostic (2.86e-3)" "unprognostic (2.39e-1)" "unprognostic (2.71e-2)" "unprognostic (2.78e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (7.28e-2)" TM9SF1 "HMP70, MP70" ENSG00000100926 "Transmembrane 9 superfamily member 1" O15321 14 24189149-24195687 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059249 Supported Approved "Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 23: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA059249: AB_2683959" "unprognostic (3.27e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (9.31e-2)" "unprognostic (1.48e-1)" "unprognostic (3.84e-2)" "unprognostic (1.19e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.62e-3)" "unprognostic (2.44e-1)" "unprognostic (4.24e-1)" "unprognostic (2.20e-1)" "unprognostic (4.18e-3)" TMBIM6 "BAXI1, BI-1, TEGT" ENSG00000139644 "Transmembrane BAX inhibitor motif containing 6" P55061 12 49707725-49764934 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1748.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 2131.1;Late spermatids: 2633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017378 Approved NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 77: Plasma cells - Protein processing" 55 "HPA017378: AB_2669604" "prognostic unfavorable (3.54e-4)" "unprognostic (6.25e-2)" "unprognostic (1.90e-2)" "unprognostic (6.52e-2)" "unprognostic (8.46e-3)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (1.22e-2)" "unprognostic (6.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.80e-1)" "prognostic favorable (1.00e-5)" "unprognostic (1.95e-1)" "unprognostic (9.27e-2)" "unprognostic (1.28e-1)" "unprognostic (1.54e-2)" TMEM101 "FLJ23987, MGC4251" ENSG00000091947 "Transmembrane protein 101" Q96IK0 17 44011188-44023946 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Glandular and luminal cells: 544.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Intercalated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039739, HPA075651" Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 51: Thyroid gland - Unknown function" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Glandular & Luminal cells - Unknown function" 11 "Nucleoplasm, Plasma membrane" "HPA039739: AB_2676657, HPA075651: " "unprognostic (1.40e-3)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" "prognostic favorable (4.29e-4)" "unprognostic (5.91e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-2)" "unprognostic (2.43e-1)" "unprognostic (2.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.10e-5)" "unprognostic (1.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" TMEM117 DKFZp434K2435 ENSG00000139173 "Transmembrane protein 117" Q9H0C3 12 43835967-44389762 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 62.2;Excitatory neurons: 212.9;Inhibitory neurons: 182.6;Microglial cells: 76.9;Oligodendrocyte precursor cells: 115.6;Oligodendrocytes: 141.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046223 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 8: Neurons - Neuronal signaling" "HPA046223: AB_10960636" "unprognostic (1.37e-2)" "unprognostic (2.99e-1)" "unprognostic (4.32e-1)" "unprognostic (2.39e-2)" "unprognostic (3.57e-2)" "unprognostic (7.08e-2)" "unprognostic (3.07e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (3.94e-4)" "unprognostic (2.89e-1)" "unprognostic (6.26e-2)" "unprognostic (1.99e-3)" "unprognostic (1.74e-2)" "unprognostic (2.30e-2)" "unprognostic (2.65e-1)" "unprognostic (9.20e-3)" "unprognostic (3.80e-1)" TMEM121 "hole, MGC4659, TMEM121A" ENSG00000184986 "Transmembrane protein 121" Q9BTD3 14 105526583-105530202 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.0" "Cell type enhanced" "Detected in many" "Endothelial cells: 14.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049857 Uncertain Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Neuronal - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 12 Cytosol "HPA049857: AB_2680917" "unprognostic (4.25e-2)" "unprognostic (3.34e-1)" "unprognostic (2.05e-3)" "unprognostic (2.20e-2)" "unprognostic (1.31e-1)" "unprognostic (9.50e-2)" "unprognostic (1.88e-3)" "unprognostic (9.54e-2)" "unprognostic (3.47e-2)" "unprognostic (1.20e-1)" "unprognostic (1.03e-3)" "unprognostic (5.31e-2)" "unprognostic (5.48e-4)" "unprognostic (2.83e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (5.90e-2)" TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.7;prostate: 6.4" "Cell type enhanced" "Detected in some" "Early spermatids: 7.0;Excitatory neurons: 6.6;Hofbauer cells: 3.1;Late spermatids: 11.4;Oligodendrocyte precursor cells: 3.3;Prostatic glandular cells: 7.6" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.7;monocytes: 1.1" "Cancer enhanced" "Detected in some" "Leukemia: 3.8;Neuroblastoma: 4.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Cardiomyocytes, Kidney - Macrophages, Prostate - Prostate glandular cells, Testis - Late spermatids, Thyroid - Macrophages" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 13: Spermatids - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 115.5;Excitatory neurons: 96.2;Inhibitory neurons: 89.8;Oligodendrocyte precursor cells: 115.6;Oligodendrocytes: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Endothelial cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" TMEM145 FLJ90805 ENSG00000167619 "Transmembrane protein 145" Q8NBT3 19 42313309-42325064 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 204.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 49.8;Cone photoreceptor cells: 25.5;Excitatory neurons: 25.6;Horizontal cells: 77.4;Inhibitory neurons: 52.1;Rod photoreceptor cells: 28.2" "Cancer enriched" "Detected in many" 5 "glioma: 8.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 5.0;neutrophil: 13.6" "Lineage enriched" "Detected in many" 11 "granulocytes: 13.6" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.6" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060462 Enhanced Approved Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Vesicles "HPA060462: AB_2684285" "unprognostic (9.56e-3)" "unprognostic (8.61e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-1)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" "unprognostic (6.62e-2)" "unprognostic (2.14e-1)" "unprognostic (4.27e-3)" "unprognostic (1.53e-2)" "unprognostic (9.85e-2)" "unprognostic (4.20e-4)" "unprognostic (7.35e-2)" "unprognostic (7.64e-2)" "unprognostic (2.30e-1)" "unprognostic (6.31e-2)" TMEM150B "DRAM3, TMEM224, TTN2" ENSG00000180061 "Transmembrane protein 150B" A6NC51 19 55312801-55334048 "Predicted membrane proteins, Transporters" Autophagy "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 5 "intestine: 62.2" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 59.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.6" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7" "Group enriched" "Detected in many" 7 "granulocytes: 1.9;monocytes: 5.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 9.3;Gastric cancer: 4.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (3.19e-2)" "unprognostic (1.00e-1)" "unprognostic (5.76e-2)" "unprognostic (4.94e-2)" "unprognostic (5.33e-2)" "unprognostic (6.70e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (5.35e-2)" "unprognostic (4.00e-2)" "unprognostic (4.74e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (6.14e-6)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "unprognostic (1.18e-2)" TMEM150C "FLJ12993, TTN3" ENSG00000249242 "Transmembrane protein 150C" B9EJG8 4 82483170-82562357 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 131.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 85.2;Syncytiotrophoblasts: 113.3" "Cancer enhanced" "Detected in all" "breast cancer: 23.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "prostate cancer: 12.3" "Kidney - Podocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052921 Enhanced NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 24: Cytotrophoblasts - Mitochondria" "HPA052921: AB_2681988" "unprognostic (2.99e-1)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.89e-3)" "unprognostic (1.71e-3)" "prognostic favorable (7.87e-4)" "unprognostic (2.94e-2)" "unprognostic (5.55e-2)" "unprognostic (1.06e-1)" "unprognostic (3.94e-2)" "prognostic favorable (5.68e-4)" "unprognostic (4.57e-2)" "prognostic favorable (4.59e-6)" "unprognostic (4.18e-1)" "unprognostic (2.64e-2)" "unprognostic (1.19e-1)" "unprognostic (3.51e-3)" TMEM161A "FLJ20422, FLJ39645" ENSG00000064545 "Transmembrane protein 161A" Q9NX61 19 19119169-19138513 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043365 Approved Approved Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 9: Endometrial stromal cells - Transcription" 2 Cytosol "HPA043365: AB_10796793" "unprognostic (4.31e-2)" "unprognostic (9.13e-2)" "unprognostic (2.34e-2)" "unprognostic (7.42e-3)" "unprognostic (6.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.12e-2)" "unprognostic (3.51e-2)" "unprognostic (2.04e-1)" "unprognostic (2.74e-1)" "unprognostic (9.42e-2)" "unprognostic (2.46e-1)" "unprognostic (9.15e-2)" "prognostic favorable (2.99e-4)" "unprognostic (4.18e-1)" "unprognostic (2.79e-1)" "unprognostic (4.89e-3)" TMEM163 "DKFZP566N034, SV31" ENSG00000152128 "Transmembrane protein 163" Q8TC26 2 134455759-134719000 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.4;pancreas: 27.0" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 54.1;Excitatory neurons: 60.1;Oligodendrocyte precursor cells: 206.1;Oocytes: 193.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 16.3" "Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007224 Uncertain NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA007224: AB_2667780" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (7.25e-3)" "unprognostic (3.18e-1)" "unprognostic (1.47e-1)" "unprognostic (2.25e-1)" "unprognostic (6.08e-3)" "prognostic favorable (7.94e-4)" "unprognostic (9.05e-2)" "unprognostic (9.62e-2)" "unprognostic (6.02e-2)" "unprognostic (2.04e-1)" "unprognostic (2.60e-2)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" "unprognostic (6.75e-3)" "prognostic favorable (3.15e-4)" TMEM165 "GDT1, SLC64A1, TMPT27, TPARL" ENSG00000134851 "Transmembrane protein 165" Q9HC07 4 55395957-55453397 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 950.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038299, HPA062424" Supported Enhanced "Golgi apparatus" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 34: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 35: Respiratory epithelial cells - Unknown function" "Golgi apparatus" "HPA038299: AB_10675793, HPA062424: AB_2732682" "unprognostic (2.53e-2)" "unprognostic (1.08e-3)" "unprognostic (3.46e-3)" "unprognostic (7.07e-3)" "unprognostic (5.97e-2)" "unprognostic (9.84e-2)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.41e-1)" "unprognostic (1.18e-2)" "unprognostic (8.00e-3)" "unprognostic (1.55e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.18e-8)" "unprognostic (9.05e-2)" "unprognostic (8.96e-2)" "unprognostic (2.72e-1)" "unprognostic (2.18e-2)" TMEM175 MGC4618 ENSG00000127419 "Transmembrane protein 175" Q9BSA9 4 932387-958656 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057160 Approved Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane" "HPA057160: AB_2683356" "unprognostic (3.84e-1)" "unprognostic (4.27e-2)" "unprognostic (1.28e-2)" "unprognostic (9.61e-3)" "unprognostic (2.43e-1)" "unprognostic (2.33e-3)" "unprognostic (1.12e-2)" "unprognostic (3.25e-3)" "unprognostic (1.22e-2)" "unprognostic (1.50e-2)" "prognostic favorable (9.85e-5)" "unprognostic (4.71e-2)" "unprognostic (5.08e-2)" "unprognostic (1.07e-1)" "unprognostic (3.74e-1)" "unprognostic (1.96e-1)" "unprognostic (7.51e-3)" TMEM184B "C22orf5, DKFZP586A1024, FM08, HS5O6A" ENSG00000198792 "Transmembrane protein 184B" Q9Y519 22 38219291-38273010 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 82.4;Oligodendrocytes: 86.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024076 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 47: Astrocytes - Unknown function" 1 "Golgi apparatus, Cytosol" Nucleoplasm "HPA024076: AB_1858106" "unprognostic (1.52e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-1)" "unprognostic (8.96e-2)" "unprognostic (3.82e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (5.94e-6)" "unprognostic (1.14e-2)" "unprognostic (5.18e-2)" "unprognostic (4.52e-2)" "unprognostic (9.20e-2)" "unprognostic (1.77e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.06e-1)" "unprognostic (2.96e-1)" TMEM185A "CXorf13, FAM11A, FRAXF" ENSG00000269556 "Transmembrane protein 185A" Q8NFB2 X 149596556-149631912 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 57: Platelets - Hemostasis" 8 "Endoplasmic reticulum" "HPA048295: AB_2680345, HPA071744: AB_2686441" "unprognostic (9.76e-2)" "unprognostic (2.83e-2)" "unprognostic (7.73e-2)" "unprognostic (2.71e-3)" "unprognostic (4.08e-1)" "unprognostic (1.97e-1)" "unprognostic (4.34e-3)" "unprognostic (1.71e-1)" "unprognostic (1.83e-1)" "unprognostic (1.92e-1)" "unprognostic (2.78e-2)" "unprognostic (2.69e-1)" "unprognostic (3.17e-1)" "unprognostic (1.37e-2)" "unprognostic (1.90e-1)" "unprognostic (1.07e-1)" "unprognostic (1.40e-1)" TMEM187 "CXorf12, DXS9878E, ITBA1" ENSG00000177854 "Transmembrane protein 187" Q14656 X 153972754-153983194 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" HPA038134 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 33: Non-specific - DNA binding" 13 "Nucleoli, Cytosol" "HPA038134: AB_10669517" "unprognostic (1.51e-1)" "unprognostic (4.35e-2)" "unprognostic (1.41e-1)" "unprognostic (1.28e-1)" "unprognostic (3.08e-1)" "unprognostic (7.88e-2)" "unprognostic (8.94e-2)" "unprognostic (2.41e-1)" "unprognostic (3.09e-1)" "unprognostic (4.22e-2)" "unprognostic (5.33e-2)" "unprognostic (7.41e-2)" "prognostic favorable (9.14e-8)" "unprognostic (6.73e-2)" "unprognostic (1.57e-1)" "unprognostic (1.05e-1)" "unprognostic (7.04e-2)" TMEM19 FLJ10936 ENSG00000139291 "Transmembrane protein 19" Q96HH6 12 71686082-71705047 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016830 Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 73: B-cells - B-cell function" 34 "HPA016830: AB_1858107" "unprognostic (8.22e-2)" "unprognostic (3.47e-2)" "unprognostic (6.76e-2)" "unprognostic (1.44e-1)" "unprognostic (4.45e-1)" "unprognostic (3.43e-2)" "unprognostic (7.60e-2)" "unprognostic (5.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-2)" "unprognostic (4.27e-2)" "unprognostic (1.49e-2)" "unprognostic (4.42e-1)" "unprognostic (5.32e-3)" "unprognostic (1.00e-1)" TMEM198 "MGC99813, TMEM198A" ENSG00000188760 "Transmembrane protein 198" Q66K66 2 219543663-219550595 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 13.9;Horizontal cells: 18.3;Muller glia cells: 11.5;Proximal enterocytes: 11.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 19.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042385, HPA062897" Enhanced Approved Vesicles NA NA "Cluster 66: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" Vesicles "HPA042385: AB_2677972, HPA062897: " "unprognostic (2.59e-2)" "unprognostic (8.51e-2)" "unprognostic (5.97e-3)" "unprognostic (2.77e-1)" "unprognostic (4.43e-2)" "unprognostic (8.09e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (4.28e-1)" "unprognostic (2.06e-1)" "prognostic favorable (6.89e-4)" "unprognostic (6.39e-2)" "unprognostic (7.91e-3)" "unprognostic (3.41e-3)" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" TMEM201 "Ima1, NET5, RP13-15M17.2, SAMP1" ENSG00000188807 "Transmembrane protein 201" Q5SNT2 1 9588911-9614877 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 41.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.3;Cone photoreceptor cells: 20.4;Rod photoreceptor cells: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB039039 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 37: Non-specific - mRNA processing" "Cluster 25: Bipolar cells - Visual perception" "Nuclear membrane" Nucleoplasm "CAB039039: " "unprognostic (1.75e-2)" "prognostic favorable (5.36e-4)" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (4.88e-1)" "unprognostic (1.27e-2)" "prognostic unfavorable (9.61e-8)" "unprognostic (2.22e-1)" "unprognostic (3.60e-1)" "unprognostic (3.87e-2)" "unprognostic (5.59e-3)" "unprognostic (1.63e-1)" "unprognostic (9.38e-2)" "unprognostic (3.87e-2)" "unprognostic (6.25e-2)" "unprognostic (7.99e-2)" "unprognostic (1.45e-1)" TMEM229A ENSG00000234224 "Transmembrane protein 229A" B2RXF0 7 124030921-124033067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.6;intestine: 8.2;testis: 5.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.0;Cytotrophoblasts: 2.8;Horizontal cells: 5.0;Oligodendrocytes: 10.6;Proximal enterocytes: 9.9;Sertoli cells: 2.7" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Bone cancer: 9.8;Neuroblastoma: 11.4" "Colon - Colon enteroendocrine cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056391 Uncertain Approved "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 22: Proximal enterocytes - Digestion" "Plasma membrane" "HPA056391: AB_2683114" "unprognostic (2.52e-2)" "unprognostic (3.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.50e-1)" "unprognostic (2.89e-2)" "unprognostic (8.21e-2)" "unprognostic (4.74e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" TMEM236 "bA162I21.2, bA16O1.2, FAM23A, FAM23B" ENSG00000148483 "Transmembrane protein 236" Q5W0B7 10 17752201-17800868 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 32.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 63.4;Enteroendocrine cells: 25.5;Intestinal goblet cells: 32.8;Paneth cells: 29.4;Proximal enterocytes: 91.3" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.7;pancreatic cancer: 0.5;stomach cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 1.3;Rhabdoid: 1.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Macrophages, Prostate - Macrophages, Skin - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045096 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 6: Leukemia - Signal transduction" "Cluster 5: Enterocytes - Absorption" 4 "HPA045096: AB_2732516" "unprognostic (4.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.88e-3)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (3.36e-2)" "unprognostic (2.52e-3)" "unprognostic (1.37e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (5.06e-3)" "unprognostic (1.75e-1)" "unprognostic (1.62e-2)" "unprognostic (1.72e-1)" "unprognostic (3.43e-2)" "unprognostic (3.16e-2)" "unprognostic (1.54e-2)" TMEM241 "C18orf45, FLJ44259, MGC11386" ENSG00000134490 "Transmembrane protein 241" Q24JQ0 18 23197144-23437961 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029489, HPA059922" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 34: Neurons - Neuronal signaling" 1 "Golgi apparatus" Vesicles "HPA029489: AB_2673067, HPA059922: AB_2684164" "unprognostic (1.44e-3)" "unprognostic (1.92e-1)" "unprognostic (7.80e-2)" "unprognostic (1.02e-2)" "unprognostic (1.37e-1)" "unprognostic (6.48e-2)" "unprognostic (1.15e-4)" "unprognostic (7.07e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (1.81e-3)" "unprognostic (9.53e-3)" "unprognostic (1.15e-1)" "unprognostic (1.42e-1)" "unprognostic (2.95e-1)" "unprognostic (4.93e-1)" "prognostic unfavorable (5.80e-4)" TMEM245 "C9orf5, CG-2" ENSG00000106771 "Transmembrane protein 245" Q9H330 9 109015135-109119947 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023892 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 72: Alveolar cells - Lung function" "Plasma membrane, Cytosol" "HPA023892: AB_1845828" "unprognostic (1.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" "unprognostic (9.58e-2)" "unprognostic (1.63e-1)" "unprognostic (6.43e-2)" "unprognostic (1.66e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.05e-1)" "unprognostic (1.85e-1)" "prognostic favorable (4.46e-9)" "unprognostic (6.11e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-1)" "unprognostic (2.24e-2)" TMEM259 "ASBABP1, C19orf6, MBRL, MGC4022" ENSG00000182087 "Transmembrane protein 259" Q4ZIN3 19 1009648-1021179 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042669, HPA054801" Approved Approved "Nuclear speckles,Endoplasmic reticulum" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 33: Non-specific - DNA binding" "Endoplasmic reticulum" "Nuclear speckles" "HPA042669: AB_10794916, HPA054801: AB_2682604" "unprognostic (1.35e-1)" "unprognostic (1.28e-1)" "unprognostic (1.41e-1)" "prognostic favorable (1.01e-4)" "unprognostic (4.12e-2)" "unprognostic (6.87e-3)" "unprognostic (2.77e-2)" "unprognostic (1.23e-1)" "unprognostic (2.20e-1)" "unprognostic (2.74e-1)" "unprognostic (4.85e-3)" "unprognostic (4.07e-2)" "unprognostic (4.81e-2)" "prognostic favorable (8.92e-6)" "unprognostic (2.47e-1)" "unprognostic (2.57e-1)" "unprognostic (4.10e-3)" TMEM26 "Em:AC068892.1, MGC35010" ENSG00000196932 "Transmembrane protein 26" Q6ZUK4 10 61406642-61453381 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 6.4;Early spermatids: 5.0;Endometrial stromal cells: 5.1;Excitatory neurons: 5.1;Inhibitory neurons: 4.6;Kupffer cells: 10.3;Late spermatids: 5.0;Sertoli cells: 5.4" "Group enriched" "Detected in some" 4 "breast cancer: 2.5;endometrial cancer: 1.0;prostate cancer: 1.8;renal cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5;Rhabdoid: 2.0" "Breast - Breast glandular cells, Liver - Kupffer cells" "Region enhanced" "Detected in some" "hypothalamus: 2.3" "Low region specificity" "Detected in all" NA NA "Cluster 47: Spleen - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 17: Breast glandular cells - Lactation" "unprognostic (1.21e-3)" "unprognostic (2.84e-1)" "unprognostic (7.34e-2)" "unprognostic (7.83e-2)" "unprognostic (1.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.56e-2)" "unprognostic (3.69e-2)" "unprognostic (3.13e-1)" "unprognostic (9.41e-2)" "unprognostic (5.38e-2)" "unprognostic (5.24e-2)" "unprognostic (2.29e-5)" "unprognostic (2.55e-2)" "unprognostic (1.51e-2)" "unprognostic (8.53e-2)" "unprognostic (1.95e-1)" TMEM41A MGC15397 ENSG00000163900 "Transmembrane protein 41A" Q96HV5 3 185476496-185499057 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 189.6;Squamous epithelial cells: 121.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "HPA059101, HPA059790" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 22: Proximal enterocytes - Digestion" 7 Nucleoplasm "Golgi apparatus, Cytosol" "HPA059101: AB_2683905, HPA059790: AB_2684125" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (6.70e-6)" "unprognostic (2.67e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (2.84e-1)" "unprognostic (1.39e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.63e-2)" "unprognostic (2.56e-2)" "unprognostic (3.73e-1)" "unprognostic (3.68e-1)" "unprognostic (1.46e-2)" "unprognostic (1.02e-2)" TMEM41B KIAA0033 ENSG00000166471 "Transmembrane protein 41B" Q5BJD5 11 9280654-9314636 "Predicted membrane proteins, Transporters" "Autophagy, Host-virus interaction, Lipid transport, Neurogenesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014946 Uncertain Approved Peroxisomes NA NA "Cluster 24: Non-specific - Transcription" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Alveolar cells - Lung function" 1 Peroxisomes "HPA014946: AB_2205037" "unprognostic (1.21e-1)" "unprognostic (2.19e-1)" "unprognostic (1.35e-1)" "unprognostic (2.75e-3)" "unprognostic (5.78e-3)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.18e-6)" "unprognostic (6.18e-2)" "unprognostic (9.37e-3)" "unprognostic (4.90e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (2.20e-1)" "unprognostic (3.55e-2)" "unprognostic (8.18e-2)" TMEM44 DKFZp686O18124 ENSG00000145014 "Transmembrane protein 44" Q2T9K0 3 194587673-194633689 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 28.2;Endothelial cells: 24.2;granulocytes: 74.2;Intestinal goblet cells: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 3.6;NK-cell: 8.3" "Group enriched" "Detected in many" 9 "granulocytes: 3.6;NK-cells: 8.3" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043718 Uncertain Approved Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 30: Granulocytes - Unknown function" Cytosol "HPA043718: AB_10794662" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (8.31e-3)" "unprognostic (4.53e-2)" "unprognostic (2.78e-3)" "unprognostic (9.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (1.70e-2)" "unprognostic (3.37e-2)" "unprognostic (1.48e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (6.55e-13)" "unprognostic (1.23e-2)" "unprognostic (3.36e-1)" "unprognostic (1.65e-3)" "unprognostic (5.66e-2)" TMEM64 DKFZp762C1112 ENSG00000180694 "Transmembrane protein 64" Q6YI46 8 90621995-90791632 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "epididymis: 141.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 49.8;Leydig cells: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB034221 Uncertain NA NA "Cluster 24: Non-specific - Transcription" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Fibroblasts - ECM organization" "CAB034221: AB_1567653" "unprognostic (3.61e-1)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (3.70e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (2.55e-3)" "unprognostic (4.84e-1)" "unprognostic (2.04e-1)" "unprognostic (1.26e-2)" "unprognostic (3.30e-1)" "unprognostic (2.35e-1)" "unprognostic (2.59e-2)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.17e-2)" "unprognostic (1.97e-1)" TMEM67 "JBTS6, MGC26979, MKS3, NPHP11" ENSG00000164953 "Transmembrane protein 67" Q5HYA8 8 93754844-93819234 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Deafness, Disease variant, Intellectual disability, Joubert syndrome, Meckel syndrome, Nephronophthisis, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 21.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 97.0;Excitatory neurons: 57.8;Rod photoreceptor cells: 82.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Vascular Endothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 17: Choroid plexus - Cilium" "Cluster 69: Skin cancer - ECM organization" "Cluster 42: Ciliated cells - Cilium assembly" "unprognostic (1.57e-3)" "unprognostic (1.22e-1)" "unprognostic (2.45e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (3.08e-1)" "unprognostic (2.25e-5)" "unprognostic (2.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.51e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (8.41e-2)" "unprognostic (2.21e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" TRAM1 "TRAM, TRAMP" ENSG00000067167 "Translocation associated membrane protein 1" Q15629 8 70573218-70608416 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Translocation, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 883.3;Plasma cells: 628.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023929 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 53: Non-specific - Glycosylation" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 77: Plasma cells - Protein processing" 2 "HPA023929: AB_1858239" "unprognostic (3.85e-2)" "prognostic unfavorable (2.06e-4)" "unprognostic (8.34e-3)" "unprognostic (1.31e-1)" "unprognostic (3.52e-2)" "unprognostic (5.93e-2)" "unprognostic (8.94e-2)" "unprognostic (2.21e-2)" "unprognostic (1.86e-1)" "unprognostic (2.12e-1)" "unprognostic (3.39e-3)" "unprognostic (3.61e-2)" "prognostic unfavorable (7.79e-4)" "unprognostic (7.45e-2)" "unprognostic (1.61e-1)" "unprognostic (2.31e-1)" "unprognostic (3.85e-2)" TRPA1 ANKTM1 ENSG00000104321 "Transient receptor potential cation channel subfamily A member 1" O75762 8 72019917-72075584 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.9;stomach 1: 10.0;urinary bladder: 26.8" "Group enriched" "Detected in some" 4 "Early spermatids: 16.0;Intestinal goblet cells: 31.9" "Cancer enhanced" "Detected in many" "breast cancer: 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.2" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" "unprognostic (2.14e-2)" "unprognostic (2.50e-2)" "prognostic favorable (6.57e-4)" "unprognostic (1.28e-2)" "unprognostic (2.34e-1)" "unprognostic (1.95e-1)" "unprognostic (1.37e-2)" "unprognostic (8.11e-3)" "unprognostic (4.22e-2)" "unprognostic (2.47e-1)" "unprognostic (2.78e-3)" "unprognostic (1.49e-1)" "unprognostic (2.16e-4)" "unprognostic (2.37e-1)" "unprognostic (9.67e-2)" "unprognostic (1.57e-1)" "unprognostic (2.90e-1)" TRPC7 ENSG00000069018 "Transient receptor potential cation channel subfamily C member 7" Q9HCX4 5 136212745-136365545 "Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bipolar cells: 5.2;Enteroendocrine cells: 3.4;Inhibitory neurons: 9.7;Oocytes: 6.6;Proximal tubular cells: 5.4;Spermatocytes: 3.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB022592, HPA031126" Uncertain NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 65: Neurons - Synaptic function" "CAB022592: , HPA031126: AB_10603221" "unprognostic (1.49e-1)" "unprognostic (2.08e-1)" "unprognostic (3.03e-2)" "unprognostic (2.89e-5)" "unprognostic (3.26e-1)" "unprognostic (2.75e-1)" "unprognostic (9.99e-2)" "unprognostic (1.77e-1)" "unprognostic (6.78e-2)" TRPM3 "GON-2, KIAA1616, LTRPC3" ENSG00000083067 "Transient receptor potential cation channel subfamily M member 3" Q9HCF6 9 70529060-71446904 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "choroid plexus: 676.9" "Cell type enhanced" "Detected in many" "Astrocytes: 858.3;Excitatory neurons: 376.7;Inhibitory neurons: 179.3;Muller glia cells: 155.8;Oligodendrocyte precursor cells: 99.0" "Cancer enhanced" "Detected in single" "renal cancer: 0.9" "Region enriched" "Detected in all" 15 "choroid plexus: 1433.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 5.1;Rhabdoid: 10.6" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Pancreas - Beta cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072650, HPA074393" Enhanced Approved Vesicles NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Neurons - Neuronal signaling" Vesicles "HPA072650: , HPA074393: " "unprognostic (3.74e-1)" "unprognostic (6.30e-2)" "unprognostic (4.79e-2)" "unprognostic (4.81e-2)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-2)" "unprognostic (1.82e-7)" "unprognostic (3.51e-2)" "unprognostic (5.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.50e-2)" TRPM5 "LTRPC5, MTR1" ENSG00000070985 "Transient receptor potential cation channel subfamily M member 5" Q9NZQ8 11 2404515-2444514 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.7;intestine: 3.2;pancreas: 2.3" "Cell type enriched" "Detected in some" 42 "Oocytes: 76.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Colon - Colon enterocytes, Prostate - Urothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 24: Non-specific - Unknown function" "Cluster 44: Oocytes - Unknown function" 1 "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (6.47e-5)" "unprognostic (6.81e-4)" "unprognostic (7.90e-3)" "unprognostic (1.18e-1)" "unprognostic (1.13e-2)" "unprognostic (2.24e-2)" "unprognostic (4.75e-1)" "unprognostic (1.53e-1)" "unprognostic (2.36e-1)" "unprognostic (3.19e-1)" "unprognostic (5.07e-3)" "unprognostic (2.40e-1)" "unprognostic (5.21e-1)" "unprognostic (5.72e-2)" "unprognostic (4.91e-2)" TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686797 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 105.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "Vesicles, Cytosol" "HPA035522: , HPA052173: AB_2681749" "unprognostic (3.14e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.60e-2)" "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (2.91e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (7.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.97e-1)" TRPV1 VR1 ENSG00000196689 "Transient receptor potential cation channel subfamily V member 1" Q8NER1 17 3565444-3609411 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 24.0" "Cell type enhanced" "Detected in many" "Astrocytes: 19.2;Oligodendrocytes: 17.5;Rod photoreceptor cells: 23.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "unprognostic (3.96e-2)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (1.33e-2)" "unprognostic (6.83e-2)" "unprognostic (3.21e-4)" "unprognostic (9.90e-2)" "unprognostic (2.95e-1)" "unprognostic (2.03e-1)" "unprognostic (2.56e-2)" "unprognostic (3.43e-3)" "unprognostic (6.17e-3)" "unprognostic (6.97e-4)" "unprognostic (4.25e-1)" "unprognostic (4.78e-1)" "unprognostic (3.81e-2)" "unprognostic (5.12e-3)" TRPV2 "VRL, VRL-1, VRL1" ENSG00000187688 "Transient receptor potential cation channel subfamily V member 2" Q9Y5S1 17 16415571-16437003 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 43.6;Hofbauer cells: 48.8;Macrophages: 34.8;Melanocytes: 51.5;NK-cells: 30.6" "Cancer enriched" "Detected in all" 8 "melanoma: 59.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "skin cancer: 81.4" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044993 Uncertain Supported "Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "HPA044993: AB_10960889" "unprognostic (1.57e-1)" "unprognostic (4.34e-3)" "unprognostic (2.05e-2)" "unprognostic (1.58e-2)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" "unprognostic (8.40e-3)" "unprognostic (2.43e-1)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (7.94e-2)" "prognostic unfavorable (5.53e-4)" "unprognostic (8.07e-2)" "unprognostic (1.23e-1)" TRPV3 VRL3 ENSG00000167723 "Transient receptor potential cation channel subfamily V member 3" Q8NET8 17 3510502-3557812 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, FDA approved drug targets, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.1;skeletal muscle: 1.5;skin 1: 4.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 13.2;Plasma cells: 14.2;Proximal enterocytes: 21.8;Schwann cells: 15.1;Skeletal myocytes: 8.8;Suprabasal keratinocytes: 13.4" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA069550 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane" "Centrosome, Cytosol" "HPA069550: AB_2686149" "unprognostic (1.84e-4)" "unprognostic (2.25e-1)" "unprognostic (5.22e-2)" "unprognostic (3.92e-4)" "unprognostic (4.87e-3)" "unprognostic (2.96e-2)" "unprognostic (6.66e-2)" "unprognostic (4.88e-2)" "unprognostic (7.02e-2)" "unprognostic (2.68e-1)" "unprognostic (4.88e-2)" "unprognostic (3.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (8.64e-2)" "unprognostic (2.93e-2)" TRPV4 "CMT2C, OTRPC4, TRP12, VR-OAC, VRL-2, VROAC" ENSG00000111199 "Transient receptor potential cation channel subfamily V member 4" Q9HBA0 12 109783087-109833406 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Charcot-Marie-Tooth disease, Disease variant, Dwarfism, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 71.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.5;Cholangiocytes: 15.3;Ciliated cells: 18.7;Cytotrophoblasts: 19.4;Ionocytes: 19.1;Kupffer cells: 14.6;Salivary duct cells: 15.0;Serous glandular cells: 15.4;Syncytiotrophoblasts: 19.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 12 "choroid plexus: 107.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 10.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" HPA007150 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA007150: AB_1080393" "unprognostic (2.98e-2)" "unprognostic (1.12e-2)" "unprognostic (2.33e-2)" "unprognostic (4.20e-3)" "unprognostic (6.25e-3)" "unprognostic (1.09e-2)" "unprognostic (7.95e-2)" "unprognostic (2.03e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.24e-1)" "unprognostic (1.68e-1)" "prognostic favorable (4.12e-5)" "unprognostic (1.20e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" TRPV5 "CaT2, ECAC1" ENSG00000127412 "Transient receptor potential cation channel subfamily V member 5" Q9NQA5 7 142908101-142933746 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 1.6;kidney: 4.3" "Cell type enriched" "Detected in some" 7 "Oligodendrocytes: 14.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA063175 Uncertain NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 66: Non-specific - Mitochondria" "Cluster 51: Oligodendrocytes - Unknown function" 1 "HPA063175: AB_2684954" "unprognostic (7.44e-2)" "unprognostic (3.93e-2)" "unprognostic (1.22e-2)" "unprognostic (4.20e-2)" "unprognostic (1.98e-1)" "unprognostic (3.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.78e-2)" "unprognostic (1.07e-1)" "unprognostic (7.95e-2)" "unprognostic (7.73e-4)" "unprognostic (4.87e-2)" "unprognostic (3.41e-1)" "unprognostic (4.58e-1)" "unprognostic (7.76e-3)" TRPV6 "CaT1, ECAC2" ENSG00000165125 "Transient receptor potential cation channel subfamily V member 6" Q9H1D0 7 142871208-142885745 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 37.2;prostate: 22.7;salivary gland: 67.4" "Cell type enhanced" "Detected in many" "Ductal cells: 90.1;Exocrine glandular cells: 22.6;Late spermatids: 40.9;Prostatic glandular cells: 53.4;Serous glandular cells: 68.3" "Cancer enriched" "Detected in many" 5 "prostate cancer: 16.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 7.9;prostate cancer: 11.5" "Adipose visceral - Mesothelial cells, Liver - Cholangiocyte, Prostate - Prostate glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA062864 Approved NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 60: Prostate cancer - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 1 "HPA062864: AB_2684885" "unprognostic (9.85e-2)" "unprognostic (1.60e-2)" "unprognostic (6.29e-2)" "unprognostic (8.72e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "unprognostic (7.11e-2)" "unprognostic (5.43e-2)" "unprognostic (3.50e-1)" "unprognostic (4.56e-2)" "unprognostic (3.89e-2)" "unprognostic (3.27e-2)" "unprognostic (8.49e-2)" "unprognostic (9.39e-3)" "unprognostic (1.69e-1)" "unprognostic (7.17e-3)" "unprognostic (3.53e-2)" UNC50 "GMH1, UNCL, URP" ENSG00000115446 "Unc-50 inner nuclear membrane RNA binding protein" Q53HI1 2 98608579-98618515 "Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 205.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027009 Approved NA NA "Cluster 41: Basophils - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 35: Respiratory epithelial cells - Unknown function" 29 "HPA027009: AB_1858620" "prognostic unfavorable (4.79e-4)" "unprognostic (3.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.74e-2)" "unprognostic (5.54e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (4.89e-5)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (5.31e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.14e-1)" "unprognostic (4.38e-1)" "unprognostic (7.12e-3)" "unprognostic (4.82e-3)" VN1R1 "V1RL1, VNR19I1, ZVNH1, ZVNR1" ENSG00000178201 "Vomeronasal 1 receptor 1" Q9GZP7 19 57454790-57457140 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 6.9;retina: 8.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.6;Cone photoreceptor cells: 1.7;dendritic cells: 1.8;Horizontal cells: 4.4;Oligodendrocyte precursor cells: 2.4;Rod photoreceptor cells: 2.5;Skeletal myocytes: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" HPA062209 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 28: Neuronal - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Vesicles Nucleoplasm "HPA062209: " "unprognostic (7.11e-2)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (1.51e-2)" "unprognostic (5.28e-2)" "unprognostic (1.01e-1)" "unprognostic (2.84e-2)" "unprognostic (1.65e-3)" "unprognostic (1.21e-2)" "unprognostic (5.41e-2)" "unprognostic (5.68e-2)" "unprognostic (2.73e-1)" "unprognostic (1.25e-2)" "unprognostic (4.59e-5)" XKR5 ENSG00000275591 "XK related 5" Q6UX68 8 6808517-6835524 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 9: Endometrial stromal cells - Transcription" "unprognostic (8.95e-2)" "unprognostic (1.72e-1)" "unprognostic (2.26e-1)" "unprognostic (2.46e-2)" "unprognostic (1.78e-1)" "unprognostic (6.73e-2)" "unprognostic (9.91e-2)" "unprognostic (2.16e-3)" "unprognostic (1.30e-1)" "unprognostic (7.91e-3)" "unprognostic (3.13e-2)" "unprognostic (9.19e-2)" "unprognostic (1.03e-2)" "unprognostic (1.76e-1)" "unprognostic (2.77e-2)" "unprognostic (4.06e-2)" XKR6 "C8orf21, C8orf5, C8orf7" ENSG00000171044 "XK related 6" Q5GH73 8 10896045-11201833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Astrocytes: 85.5;Excitatory neurons: 404.8;Inhibitory neurons: 325.4;Microglial cells: 102.0;Oligodendrocyte precursor cells: 272.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024828, HPA064769" Approved "Actin filaments" NA NA "Cluster 46: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 8: Neurons - Neuronal signaling" "Actin filaments" "HPA024828: AB_2215165, HPA064769: AB_2732720" "unprognostic (8.63e-3)" "unprognostic (8.45e-2)" "unprognostic (1.50e-1)" "unprognostic (9.92e-6)" "unprognostic (2.09e-1)" "unprognostic (2.51e-2)" "unprognostic (1.18e-1)" "unprognostic (8.75e-3)" "unprognostic (8.65e-2)" "unprognostic (7.09e-2)" "unprognostic (2.87e-1)" "unprognostic (1.31e-1)" "unprognostic (3.78e-2)" "unprognostic (3.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.58e-1)" "unprognostic (3.29e-3)" XKR8 FLJ10307 ENSG00000158156 "XK related 8" Q9H6D3 1 27959588-27968093 "Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "eosinophil: 203.2;neutrophil: 102.0" "Lineage enriched" "Detected in all" 13 "granulocytes: 203.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049984, HPA053529" Uncertain Approved "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus" "HPA049984: AB_2680982, HPA053529: AB_2682179" "prognostic favorable (8.63e-4)" "unprognostic (2.15e-1)" "unprognostic (2.40e-1)" "unprognostic (1.10e-3)" "unprognostic (1.97e-2)" "unprognostic (1.38e-2)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (7.87e-2)" "unprognostic (8.41e-2)" "unprognostic (1.83e-3)" "unprognostic (6.29e-2)" "unprognostic (8.55e-2)" "unprognostic (2.93e-2)" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (4.20e-2)" ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 136.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 21: Early spermatids - Spermatogenesis" Vesicles "Golgi apparatus" "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" ZDHHC17 "HIP14, HYPH, KIAA0946" ENSG00000186908 "Zinc finger DHHC-type palmitoyltransferase 17" Q8IUH5 12 76764103-76853696 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 111.0;Excitatory neurons: 98.8;Inhibitory neurons: 91.1;Oligodendrocytes: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 17.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016807 Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 28: Neuronal - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 28: Dendritic cells - Antigen presentation" 30 "Golgi apparatus" Vesicles "HPA016807: AB_1858999" "unprognostic (1.06e-1)" "unprognostic (2.26e-2)" "unprognostic (2.63e-2)" "unprognostic (3.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-3)" "unprognostic (3.09e-1)" "unprognostic (8.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.56e-3)" "unprognostic (5.42e-2)" "prognostic unfavorable (7.11e-5)" "unprognostic (1.77e-2)" "unprognostic (2.69e-1)" "unprognostic (2.98e-1)" "unprognostic (1.71e-2)"