Gene	"Gene synonym"	Ensembl	"Gene description"	Uniprot	Chromosome	Position	"Protein class"	"Biological process"	"Molecular function"	"Disease involvement"	Evidence	"HPA evidence"	"UniProt evidence"	"NeXtProt evidence"	"RNA tissue specificity"	"RNA tissue distribution"	"RNA tissue specificity score"	"RNA tissue specific nTPM"	"RNA single cell type specificity"	"RNA single cell type distribution"	"RNA single cell type specificity score"	"RNA single cell type specific nCPM"	"RNA single nuclei brain specificity"	"RNA single nuclei brain distribution"	"RNA single nuclei brain specificity score"	"RNA single nuclei brain specific nCPM"	"RNA cancer specificity"	"RNA cancer distribution"	"RNA cancer specificity score"	"RNA cancer specific pTPM"	"RNA brain regional specificity"	"RNA brain regional distribution"	"RNA brain regional specificity score"	"RNA brain regional specific nTPM"	"RNA blood cell specificity"	"RNA blood cell distribution"	"RNA blood cell specificity score"	"RNA blood cell specific nTPM"	"RNA blood lineage specificity"	"RNA blood lineage distribution"	"RNA blood lineage specificity score"	"RNA blood lineage specific nTPM"	"RNA cell line specificity"	"RNA cell line distribution"	"RNA cell line specificity score"	"RNA cell line specific nTPM"	"RNA tissue cell type enrichment"	"RNA mouse brain regional specificity"	"RNA mouse brain regional distribution"	"RNA mouse brain regional specificity score"	"RNA mouse brain regional specific nTPM"	"RNA pig brain regional specificity"	"RNA pig brain regional distribution"	"RNA pig brain regional specificity score"	"RNA pig brain regional specific nTPM"	Antibody	"Reliability (IH)"	"Reliability (Mouse Brain)"	"Reliability (IF)"	"Subcellular location"	"Secretome location"	"Secretome function"	"CCD Protein"	"CCD Transcript"	"Blood concentration - Conc. blood IM [pg/L]"	"Blood concentration - Conc. blood MS [pg/L]"	"Blood expression cluster"	"Tissue expression cluster"	"Brain expression cluster"	"Cell line expression cluster"	"Single cell expression cluster"	Interactions	"Subcellular main location"	"Subcellular additional location"	"Antibody RRID"	"Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)"	"Cancer prognostics - Breast Invasive Carcinoma (TCGA)"	"Cancer prognostics - Breast Invasive Carcinoma (validation)"	"Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)"	"Cancer prognostics - Colon Adenocarcinoma (TCGA)"	"Cancer prognostics - Colon Adenocarcinoma (validation)"	"Cancer prognostics - Glioblastoma Multiforme (TCGA)"	"Cancer prognostics - Glioblastoma Multiforme (validation)"	"Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)"	"Cancer prognostics - Kidney Chromophobe (TCGA)"	"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)"	"Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)"	"Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)"	"Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)"	"Cancer prognostics - Liver Hepatocellular Carcinoma (validation)"	"Cancer prognostics - Lung Adenocarcinoma (TCGA)"	"Cancer prognostics - Lung Adenocarcinoma (validation)"	"Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)"	"Cancer prognostics - Lung Squamous Cell Carcinoma (validation)"	"Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)"	"Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)"	"Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)"	"Cancer prognostics - Pancreatic Adenocarcinoma (validation)"	"Cancer prognostics - Prostate Adenocarcinoma (TCGA)"	"Cancer prognostics - Rectum Adenocarcinoma (TCGA)"	"Cancer prognostics - Rectum Adenocarcinoma (validation)"	"Cancer prognostics - Skin Cutaneous Melanoma (TCGA)"	"Cancer prognostics - Stomach Adenocarcinoma (TCGA)"	"Cancer prognostics - Testicular Germ Cell Tumor (TCGA)"	"Cancer prognostics - Thyroid Carcinoma (TCGA)"	"Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)"
ARHGAP35	"GRF-1, GRLF1, KIAA1722, P190A, p190ARhoGAP, p190RhoGAP"	ENSG00000160007	"Rho GTPase activating protein 35"	Q9NRY4	19	46860997-47005077	"Cancer-related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"DNA-binding, GTPase activation, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	5	"Late spermatids: 1189.7"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in all"			"Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB037311, HPA055184, HPA056470"	Approved		Approved	"Nuclear bodies,Microtubules,Aggresome"			NA	NA			"Cluster 30: Non-specific - DNA binding"	"Cluster 25: Non-specific - Basic cellular processes"	"Cluster 38: Sub-cortical - Mixed function"	"Cluster 4: Non-specific - Transcription"	"Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization"	12	"Nuclear bodies"	"Microtubules, Aggresome"	"CAB037311: , HPA055184: , HPA056470: "	"unprognostic (3.73e-2)"	"unprognostic (1.63e-2)"		"unprognostic (1.29e-3)"	"unprognostic (1.69e-2)"	"unprognostic (4.89e-2)"	"unprognostic (5.11e-3)"	"unprognostic (1.54e-1)"	"unprognostic (3.90e-2)"	"unprognostic (4.69e-1)"	"validated prognostic favorable (8.75e-9)"	"validated prognostic favorable (9.71e-4)"	"unprognostic (3.04e-2)"	"unprognostic (5.91e-3)"	"unprognostic (1.97e-1)"	"unprognostic (8.54e-2)"	"unprognostic (2.53e-1)"	"unprognostic (1.13e-1)"	"unprognostic (2.93e-2)"	"unprognostic (2.98e-2)"	"unprognostic (3.29e-2)"	"unprognostic (5.18e-2)"	"unprognostic (3.09e-1)"	"unprognostic (2.88e-1)"	"unprognostic (1.36e-2)"	"unprognostic (1.70e-1)"	"unprognostic (1.13e-1)"	"unprognostic (2.72e-1)"	"unprognostic (2.21e-1)"	"unprognostic (1.47e-1)"	"unprognostic (1.47e-1)"
ARID1B	"6A3-5, BAF250b, DAN15, ELD/OSA1, KIAA1235, p250R, SMARCF2"	ENSG00000049618	"AT-rich interaction domain 1B"	Q8NFD5	6	156776020-157210779	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Neurogenesis, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA016511, HPA075291"	Approved		Supported	"Nucleoplasm,Plasma membrane,Cytosol"			NA	NA			"Cluster 24: Non-specific - Transcription"	"Cluster 63: Non-specific - Basic cellular processes"	"Cluster 15: Non-specific - Transcription"	"Cluster 28: Non-specific - Nuclear processes"	"Cluster 7: Non-specific - Transcription"	65	Nucleoplasm	"Plasma membrane, Cytosol"	"HPA016511: , HPA075291: "	"unprognostic (7.41e-3)"	"potential prognostic unfavorable (1.01e-5)"	"unprognostic (3.87e-3)"	"unprognostic (5.63e-3)"	"unprognostic (7.64e-2)"	"unprognostic (1.66e-1)"	"unprognostic (9.44e-2)"	"unprognostic (4.95e-2)"	"unprognostic (1.77e-2)"	"unprognostic (6.03e-2)"	"potential prognostic favorable (1.12e-4)"	"unprognostic (1.41e-2)"	"unprognostic (2.37e-2)"	"potential prognostic unfavorable (2.90e-4)"	"unprognostic (4.49e-1)"	"unprognostic (9.38e-2)"	"unprognostic (1.84e-1)"	"unprognostic (1.45e-1)"	"unprognostic (1.29e-1)"	"unprognostic (1.03e-3)"	"unprognostic (1.08e-1)"	"unprognostic (2.08e-1)"	"unprognostic (5.28e-2)"	"unprognostic (1.63e-1)"	"unprognostic (5.47e-3)"	"unprognostic (4.10e-3)"	"unprognostic (1.19e-1)"	"unprognostic (2.90e-1)"	"unprognostic (3.19e-1)"	"unprognostic (3.10e-1)"	"unprognostic (6.47e-2)"
ATP1A1		ENSG00000163399	"ATPase Na+/K+ transporting subunit alpha 1"	P05023	1	116372668-116410261	"Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters"	"Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport"	Translocase	"Cancer-related genes, Charcot-Marie-Tooth disease, Epilepsy, FDA approved drug targets, Intellectual disability, Neurodegeneration, Neuropathy, Primary hypomagnesemia"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"parathyroid gland: 1394.0"	"Cell type enhanced"	"Detected in all"		"Alveolar cells type 1: 1174.7;Distal convoluted tubule cells: 1212.2;Enterocytes: 1869.7;Salivary duct cells: 1630.3;Salivary ionocytes: 1393.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Lung - Alveolar cells type 2, Thyroid gland - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB018702, CAB069993"	Enhanced		Approved	"Vesicles,Plasma membrane"			NA	NA		780000	"Cluster 33: Non-specific - ATP binding"	"Cluster 76: Non-specific - Metabolism"	"Cluster 52: Neurons & Synapses - Synaptic function"	"Cluster 70: DU4475 - Unknown function"	"Cluster 1: Enterocytes - Absorption and Digestion"	68	"Vesicles, Plasma membrane"		"CAB018702: , CAB069993: "	"unprognostic (4.76e-1)"	"unprognostic (3.62e-1)"	"unprognostic (1.57e-1)"	"unprognostic (8.64e-2)"	"unprognostic (2.17e-2)"	"unprognostic (1.14e-1)"	"unprognostic (9.16e-2)"	"unprognostic (1.72e-2)"	"unprognostic (3.44e-1)"	"unprognostic (2.06e-2)"	"potential prognostic favorable (3.15e-6)"	"unprognostic (3.56e-2)"	"unprognostic (4.24e-3)"	"potential prognostic unfavorable (2.62e-4)"	"unprognostic (1.60e-3)"	"unprognostic (1.17e-1)"	"unprognostic (8.11e-2)"	"unprognostic (9.61e-2)"	"unprognostic (1.59e-1)"	"unprognostic (4.77e-2)"	"unprognostic (3.03e-1)"	"unprognostic (1.81e-2)"	"unprognostic (3.56e-1)"	"unprognostic (3.42e-1)"	"unprognostic (2.32e-1)"	"unprognostic (1.23e-1)"	"unprognostic (1.29e-2)"	"unprognostic (8.88e-2)"	"unprognostic (1.04e-1)"	"unprognostic (1.51e-1)"	"unprognostic (3.47e-2)"
ATP2B3	"CFAP39, CLA2, PMCA3, SCAX1"	ENSG00000067842	"ATPase plasma membrane Ca2+ transporting 3"	Q16720	X	153517642-153582939	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Calcium transport, Ion transport, Transport"	"Calmodulin-binding, Translocase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	7	"choroid plexus: 106.2"	"Cell type enriched"	"Detected in some"	6	"Choroid plexus epithelial cells: 197.4"	"Cell type enhanced"	"Detected in many"		"choroid plexus epithelial cell: 159.2"	"Not detected"	"Not detected"			"Region enhanced"	"Detected in all"		"choroid plexus: 503.4"	"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in some"		"Bone cancer: 4.9;Neuroblastoma: 9.1"	"Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Pituitary gland - Gonadotropes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001583, HPA064779"	Enhanced	Supported	Approved	"Nucleoplasm,Plasma membrane"			NA	NA				"Cluster 1: Choroid plexus - Transmembrane transport"	"Cluster 23: Choroid plexus - Mixed function"	"Cluster 1: Neuronal - Visual perception"	"Cluster 101: Choroid plexus epithelial cells - Ion transport"	3	"Nucleoplasm, Plasma membrane"		"HPA001583: , HPA064779: "								"unprognostic (1.63e-2)"																							
BAP1	"hucep-6, KIAA0272, UCHL2"	ENSG00000163930	"BRCA1 associated protein 1"	Q92560	3	52401008-52410008	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins"	"Differentiation, Ubl conjugation pathway"	"Chromatin regulator, Developmental protein, Hydrolase, Protease, Thiol protease"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Early spermatids: 108.8;Late primary spermatocytes: 65.9;Late spermatids: 61.4"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004322, HPA028814, HPA028815, HPA055560"	Approved		Supported	Nucleoplasm,Cytosol			NA	NA			"Cluster 29: Non-specific - Unknown function"	"Cluster 67: Testis - Mixed function"	"Cluster 51: Neurons - Mixed function"	"Cluster 8: Non-specific - Basic cellular processes"	"Cluster 33: Early spermatids - Spermiogenesis: Cap phase"	139	Nucleoplasm	Cytosol	"CAB004322: , HPA028814: , HPA028815: , HPA055560: "	"unprognostic (1.90e-1)"	"unprognostic (3.72e-1)"	"unprognostic (3.09e-1)"	"unprognostic (1.54e-1)"	"unprognostic (2.91e-2)"	"unprognostic (1.32e-1)"	"unprognostic (1.53e-1)"	"unprognostic (1.66e-1)"	"unprognostic (4.46e-2)"	"unprognostic (7.10e-2)"	"unprognostic (2.25e-2)"	"unprognostic (2.01e-2)"	"unprognostic (2.41e-3)"	"unprognostic (2.26e-3)"	"unprognostic (2.68e-2)"	"unprognostic (2.30e-2)"	"unprognostic (2.91e-2)"	"unprognostic (1.29e-2)"	"unprognostic (2.31e-3)"	"unprognostic (5.17e-1)"	"unprognostic (8.68e-2)"	"unprognostic (7.46e-3)"	"unprognostic (9.82e-2)"	"unprognostic (3.93e-3)"	"unprognostic (4.55e-2)"	"unprognostic (3.19e-2)"	"unprognostic (3.58e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.66e-1)"	"unprognostic (5.86e-2)"	"unprognostic (3.20e-2)"
BRAF	"BRAF-1, BRAF1"	ENSG00000157764	"B-Raf proto-oncogene, serine/threonine kinase"	P15056	7	140719327-140924929	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters"		"Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Neutrophils: 2034.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Pancreas - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001328, CAB004552, HPA071048, CAB080447, CAB080451, CAB080452, CAB080531"	Supported		Supported	"Vesicles,Plasma membrane,Primary cilium,Centriolar satellite,Basal body,Cytosol,Mid piece,Principal piece,End piece"			No	No			"Cluster 20: Non-specific - DNA binding"	"Cluster 44: Bone marrow - Nuclear processes"	"Cluster 31: Non-specific - Transcription"	"Cluster 39: Non-specific - Transcription"	"Cluster 31: Neutrophils - Chemotaxis & Apoptosis"	174	"Vesicles, Cytosol"	"Plasma membrane, Primary cilium, Centriolar satellite, Basal body, Mid piece, Principal piece, End piece"	"CAB004552: , CAB080447: , CAB080451: , CAB080452: , CAB080531: , HPA001328: , HPA071048: "	"potential prognostic favorable (4.52e-4)"	"unprognostic (8.04e-3)"	"unprognostic (2.25e-1)"	"unprognostic (1.00e-1)"	"unprognostic (6.81e-2)"	"unprognostic (1.39e-1)"	"unprognostic (1.64e-1)"	"unprognostic (1.79e-2)"	"unprognostic (2.07e-2)"	"unprognostic (4.01e-2)"	"validated prognostic favorable (1.04e-4)"	"validated prognostic favorable (2.24e-4)"	"unprognostic (1.26e-1)"	"unprognostic (3.93e-2)"	"unprognostic (1.48e-1)"	"unprognostic (7.31e-2)"	"unprognostic (7.33e-3)"	"unprognostic (1.95e-1)"	"unprognostic (1.82e-1)"	"unprognostic (7.86e-2)"	"potential prognostic unfavorable (1.29e-4)"	"unprognostic (2.08e-1)"	"unprognostic (2.47e-2)"	"unprognostic (1.21e-1)"	"unprognostic (8.43e-2)"	"unprognostic (2.20e-3)"	"unprognostic (5.50e-2)"	"unprognostic (2.47e-1)"	"unprognostic (1.41e-1)"	"unprognostic (1.77e-2)"	"unprognostic (6.27e-2)"
CBL	"c-Cbl, CBL2, RNF55"	ENSG00000110395	"Cbl proto-oncogene"	P22681	11	119206298-119313926	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Ubl conjugation pathway"	Transferase	"Cancer-related genes, Disease variant, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Neutrophil progenitors: 368.6;Neutrophils: 711.6"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"neutrophil: 8.2"	"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004350, HPA027956"	Enhanced		Supported	"Mitotic spindle,Cytosol,End piece"			Yes	NA		160000	"Cluster 7: Non-specific - Innate immune response"	"Cluster 51: Lymphoid tissue - Adaptive immune response"	"Cluster 19: Astrocytes - Mixed function"	"Cluster 24: Non-specific - Unknown function"	"Cluster 24: Neutrophils - Innate immunity signal integration"	201	Cytosol	"Mitotic spindle, End piece"	"CAB004350: , HPA027956: "	"unprognostic (2.86e-2)"	"unprognostic (9.42e-2)"	"unprognostic (4.42e-1)"	"unprognostic (4.47e-3)"	"unprognostic (3.79e-1)"	"unprognostic (3.63e-2)"	"unprognostic (2.88e-2)"	"unprognostic (1.18e-1)"	"unprognostic (1.83e-1)"	"potential prognostic unfavorable (5.63e-4)"	"validated prognostic favorable (3.43e-4)"	"validated prognostic favorable (7.67e-4)"	"unprognostic (2.75e-2)"	"unprognostic (2.08e-3)"	"unprognostic (2.43e-1)"	"unprognostic (1.49e-1)"	"unprognostic (1.84e-3)"	"unprognostic (1.35e-1)"	"unprognostic (1.68e-1)"	"unprognostic (1.96e-2)"	"unprognostic (1.45e-3)"	"unprognostic (2.46e-2)"	"unprognostic (5.99e-3)"	"unprognostic (5.03e-2)"	"unprognostic (6.24e-2)"	"unprognostic (5.49e-2)"	"unprognostic (3.35e-2)"	"unprognostic (8.38e-2)"	"unprognostic (1.53e-1)"	"unprognostic (8.97e-2)"	"unprognostic (1.35e-1)"
CREBBP	"CBP, KAT3A, RSTS, RTS"	ENSG00000005339	"CREB binding protein"	Q92793	16	3725054-3880713	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins"	"Biological rhythms, Host-virus interaction, Transcription, Transcription regulation"	"Activator, Acyltransferase, Transferase"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Neutrophils: 1399.6"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Spermatocytes, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004212, HPA055861"	Supported		Enhanced	"Nucleoplasm,Nuclear bodies"			No	No			"Cluster 20: Non-specific - DNA binding"	"Cluster 61: Non-specific - Transcription"	"Cluster 15: Non-specific - Transcription"	"Cluster 54: Non-specific - Transcription"	"Cluster 24: Neutrophils - Innate immunity signal integration"	260	"Nucleoplasm, Nuclear bodies"		"CAB004212: , HPA055861: "	"unprognostic (3.44e-3)"	"unprognostic (1.50e-1)"	"unprognostic (2.44e-1)"	"unprognostic (6.42e-2)"	"unprognostic (2.35e-1)"	"unprognostic (2.08e-2)"	"unprognostic (2.99e-1)"	"unprognostic (1.29e-1)"	"unprognostic (7.44e-2)"	"unprognostic (5.48e-2)"	"validated prognostic favorable (1.90e-6)"	"validated prognostic favorable (7.46e-4)"	"unprognostic (2.43e-1)"	"unprognostic (3.46e-3)"	"unprognostic (3.97e-1)"	"unprognostic (2.14e-1)"	"unprognostic (6.45e-2)"	"unprognostic (2.39e-1)"	"unprognostic (4.87e-2)"	"unprognostic (8.24e-2)"	"unprognostic (1.16e-1)"	"unprognostic (1.22e-1)"	"unprognostic (1.20e-3)"	"unprognostic (1.49e-1)"	"unprognostic (2.65e-2)"	"unprognostic (3.10e-2)"	"unprognostic (7.99e-2)"	"unprognostic (7.88e-2)"	"unprognostic (1.67e-1)"	"unprognostic (7.22e-3)"	"unprognostic (8.97e-2)"
CTNNB1	"armadillo, beta-catenin, CTNNB"	ENSG00000168036	"Catenin beta 1"	P35222	3	41194741-41260096	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway"	Activator	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"monocytes: 871.7"	"Cell type enhanced"	"Detected in all"		"endothelial cell: 823.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000108, CAB001950, HPA029159, HPA029160"	Supported		Enhanced	"Plasma membrane,Cell Junctions,Primary cilium,Basal body"			NA	NA		3200000	"Cluster 33: Non-specific - ATP binding"	"Cluster 75: Ovary - Mixed function"	"Cluster 44: Non-specific - Mixed function"	"Cluster 9: Skin cancer - Melanin biosynthesis"	"Cluster 40: Monocytes & Neutrophils - Inflammatory signaling"	443	"Plasma membrane"	"Cell Junctions, Primary cilium, Basal body"	"CAB000108: , CAB001950: , HPA029159: , HPA029160: "	"unprognostic (1.79e-2)"	"unprognostic (8.56e-2)"	"unprognostic (1.15e-1)"	"unprognostic (5.61e-3)"	"unprognostic (3.56e-2)"	"unprognostic (3.47e-1)"	"unprognostic (1.20e-1)"	"unprognostic (5.18e-2)"	"unprognostic (3.77e-2)"	"potential prognostic unfavorable (4.23e-4)"	"validated prognostic favorable (6.88e-8)"	"validated prognostic favorable (1.81e-5)"	"unprognostic (3.52e-2)"	"potential prognostic unfavorable (6.51e-4)"	"unprognostic (1.47e-2)"	"unprognostic (2.35e-1)"	"unprognostic (1.78e-2)"	"unprognostic (1.00e-1)"	"unprognostic (2.01e-1)"	"unprognostic (4.61e-2)"	"unprognostic (8.64e-3)"	"unprognostic (1.26e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.63e-1)"	"unprognostic (3.63e-3)"	"unprognostic (8.27e-2)"	"unprognostic (2.22e-1)"	"unprognostic (7.32e-3)"	"unprognostic (2.73e-1)"	"unprognostic (1.60e-1)"	"unprognostic (4.10e-3)"
CUX1	"CASP, CDP, CDP/Cut, CDP/Cux, CDP1, Clox, CUT, CUTL1, CUX, Cux/CDP, GOLIM6"	ENSG00000257923	"Cut like homeobox 1"	"P39880, Q13948"	7	101815904-102283958	"Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors"	"Transcription, Transcription regulation, Transport"	"Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Neutrophils: 2269.5"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"non-classical monocyte: 35.1"	"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Thyroid gland - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003277, HPA003317"	Approved		Supported	"Nucleoplasm,Golgi apparatus"			NA	NA			"Cluster 10: Non-specific - Membrane trafficking"	"Cluster 41: Striated muscle - Muscle contraction"	"Cluster 2: Neurons - Nucleosome"	"Cluster 39: Non-specific - Transcription"	"Cluster 48: Neutrophils - Phagocytosis & degranulation"	22	"Nucleoplasm, Golgi apparatus"		"HPA003277: , HPA003317: "	"unprognostic (3.37e-1)"	"unprognostic (1.67e-2)"	"unprognostic (3.29e-1)"	"unprognostic (4.11e-3)"	"unprognostic (1.10e-2)"	"unprognostic (1.31e-1)"	"unprognostic (1.64e-2)"	"unprognostic (2.55e-1)"	"unprognostic (5.17e-2)"	"unprognostic (1.40e-2)"	"potential prognostic favorable (4.91e-5)"	"unprognostic (2.35e-1)"	"unprognostic (1.71e-2)"	"unprognostic (4.67e-1)"	"unprognostic (4.14e-1)"	"unprognostic (5.54e-2)"	"unprognostic (5.71e-2)"	"unprognostic (4.48e-2)"	"unprognostic (2.38e-2)"	"unprognostic (1.30e-3)"	"unprognostic (5.74e-2)"	"unprognostic (1.55e-1)"	"unprognostic (1.22e-2)"	"unprognostic (3.52e-1)"	"unprognostic (5.12e-2)"	"unprognostic (3.38e-1)"	"unprognostic (3.02e-1)"	"unprognostic (5.47e-2)"	"unprognostic (2.75e-1)"	"unprognostic (9.33e-3)"	"unprognostic (9.37e-2)"
DNM2	"CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII"	ENSG00000079805	"Dynamin 2"	P50570	19	10718055-10833488	"Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters"	"Endocytosis, Phagocytosis"	"Hydrolase, Motor protein"	"Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Neutrophils: 569.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Stomach - Gastric mucous cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA054246	Supported		Supported	"Golgi apparatus,Cytosol"			NA	NA		150000	"Cluster 29: Non-specific - Unknown function"	"Cluster 63: Non-specific - Basic cellular processes"	"Cluster 30: White matter - Myelination"	"Cluster 23: Non-specific - Transcription"	"Cluster 48: Neutrophils - Phagocytosis & degranulation"	65	"Golgi apparatus, Cytosol"		"HPA054246: "	"unprognostic (3.08e-2)"	"unprognostic (1.48e-1)"	"unprognostic (1.26e-2)"	"unprognostic (1.60e-1)"	"unprognostic (1.74e-1)"	"unprognostic (3.58e-2)"	"unprognostic (2.26e-1)"	"unprognostic (7.90e-2)"	"potential prognostic favorable (5.81e-4)"	"unprognostic (4.66e-3)"	"potential prognostic favorable (1.55e-4)"	"unprognostic (1.27e-1)"	"unprognostic (2.76e-1)"	"unprognostic (3.43e-3)"	"unprognostic (2.15e-2)"	"unprognostic (4.69e-1)"	"unprognostic (6.57e-2)"	"unprognostic (1.80e-1)"	"unprognostic (1.07e-1)"	"unprognostic (1.62e-1)"	"unprognostic (2.35e-1)"	"unprognostic (1.04e-2)"	"unprognostic (9.77e-2)"	"unprognostic (3.82e-2)"	"unprognostic (7.23e-2)"	"unprognostic (1.41e-1)"	"unprognostic (1.56e-1)"	"unprognostic (5.63e-2)"	"unprognostic (5.38e-2)"	"unprognostic (1.71e-1)"	"unprognostic (8.70e-2)"
EGFR	"ERBB, ERBB1, ERRP"	ENSG00000146648	"Epidermal growth factor receptor"	P00533	7	55019017-55211628	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters"	"Host-virus interaction"	"Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"placenta: 61.8"	"Cell type enhanced"	"Detected in many"		"Cytotrophoblasts: 1190.3;Fibro-adipogenic progenitors: 1097.7;Myosatellite cells: 789.2;Respiratory basal cells: 935.5;Syncytiotrophoblasts: 1481.8"	"Cell type enhanced"	"Detected in many"		"astrocyte: 363.8;Bergmann glia: 419.5"	"Cancer enriched"	"Detected in all"	4	"Glioblastoma Multiforme (TCGA): 324.2"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in many"			"Prostate - Prostate basal glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000035, HPA001200, HPA018530, CAB068186, CAB073534, CAB080313, CAB080314, CAB080473, CAB080474, CAB080475, CAB080506, CAB080507, CAB080508, CAB080509, CAB080510, CAB080511, CAB080513"	Enhanced		Supported	"Golgi apparatus,Plasma membrane,Cell Junctions,Primary cilium,Basal body,Mid piece,Principal piece,End piece"	"Secreted to blood"	Receptor	NA	NA	4740000	19000000		"Cluster 11: Esophagus - Basic cellular processes"	"Cluster 19: Astrocytes - Mixed function"	"Cluster 53: Squamous epithelial cells - Keratinization"	"Cluster 108: Fibroblasts - ECM organization"	926	"Golgi apparatus, Plasma membrane"	"Cell Junctions, Primary cilium, Basal body, Mid piece, Principal piece, End piece"	"CAB000035: , CAB068186: , CAB073534: , CAB080313: , CAB080314: , CAB080473: , CAB080474: , CAB080475: , CAB080506: , CAB080507: , CAB080508: , CAB080509: , CAB080510: , CAB080511: , CAB080513: , HPA001200: , HPA018530: "	"unprognostic (7.14e-2)"	"unprognostic (2.28e-2)"	"unprognostic (9.66e-2)"	"unprognostic (2.14e-3)"	"unprognostic (9.48e-2)"	"unprognostic (9.42e-2)"	"unprognostic (1.44e-1)"	"unprognostic (2.07e-2)"	"unprognostic (3.73e-2)"	"unprognostic (2.68e-3)"	"potential prognostic favorable (8.23e-5)"	"unprognostic (1.24e-2)"	"unprognostic (1.11e-1)"	"unprognostic (1.35e-1)"	"unprognostic (1.01e-2)"	"unprognostic (4.78e-2)"	"unprognostic (1.38e-1)"	"unprognostic (6.90e-2)"	"unprognostic (2.25e-1)"	"unprognostic (3.35e-3)"	"unprognostic (2.91e-1)"	"unprognostic (5.73e-3)"	"potential prognostic unfavorable (4.42e-5)"	"unprognostic (1.11e-1)"	"unprognostic (3.51e-2)"	"unprognostic (1.84e-1)"	"unprognostic (1.92e-2)"	"unprognostic (4.08e-2)"	"unprognostic (1.52e-1)"	"unprognostic (4.14e-2)"	"unprognostic (9.81e-2)"
EP300	"KAT3B, p300"	ENSG00000100393	"E1A binding protein p300"	Q09472	22	41092592-41180077	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins"	"Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation"	"Acyltransferase, Transferase"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Neutrophil progenitors: 447.5;Neutrophils: 860.7"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in some"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB000146, HPA003128, HPA004112"	Supported		Supported	Nucleoplasm,Centrosome,Cytosol			NA	NA			"Cluster 20: Non-specific - DNA binding"	"Cluster 63: Non-specific - Basic cellular processes"	"Cluster 16: Non-specific - Transcription"	"Cluster 66: Non-specific - Mitochondria"	"Cluster 29: Neutrophils - Innate immune cellular maintenance"	438	Nucleoplasm	"Centrosome, Cytosol"	"CAB000146: , HPA003128: , HPA004112: "	"unprognostic (7.02e-2)"	"unprognostic (1.18e-1)"	"unprognostic (9.89e-2)"	"unprognostic (4.26e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.02e-3)"	"unprognostic (1.76e-2)"	"unprognostic (2.79e-1)"	"unprognostic (1.92e-1)"	"unprognostic (1.27e-1)"	"validated prognostic favorable (1.07e-5)"	"validated prognostic favorable (1.68e-5)"	"unprognostic (1.22e-1)"	"unprognostic (1.76e-2)"	"unprognostic (3.30e-1)"	"unprognostic (8.42e-2)"	"unprognostic (1.01e-1)"	"unprognostic (7.79e-3)"	"unprognostic (1.30e-3)"	"unprognostic (2.35e-2)"	"unprognostic (7.28e-2)"	"unprognostic (7.45e-2)"	"unprognostic (1.30e-1)"	"unprognostic (1.61e-1)"	"unprognostic (5.65e-3)"	"unprognostic (1.62e-2)"	"unprognostic (1.87e-1)"	"unprognostic (2.89e-1)"	"unprognostic (2.88e-1)"	"unprognostic (3.25e-2)"	"unprognostic (2.50e-2)"
ERBB2	"c-ERB-2, c-ERB2, CD340, HER-2, HER2, MLN-19, NEU, NGL, p185(erbB2)"	ENSG00000141736	"Erb-b2 receptor tyrosine kinase 2"	P04626	17	39687914-39730426	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters"	"Transcription, Transcription regulation"	"Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Esophageal apical cells: 241.3;Prostatic club cells: 178.9"	"Group enriched"	"Detected in many"	4	"astrocyte: 27.0;Bergmann glia: 16.9;choroid plexus epithelial cell: 15.4;ependymal cell: 55.2;fibroblast: 34.0;pericyte: 14.2;vascular associated smooth muscle cell: 20.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"gdT-cell: 5.0"	"Group enriched"	"Detected in many"	5	"granulocytes: 1.2;T-cells: 5.0"	"Group enriched"	"Detected in all"	5	"breast cancer: 705.7;Esophageal cancer: 445.4;Gastric cancer: 199.3"	"Adrenal gland - Fibroblasts, Breast - Breast glandular cells, Lung - Alveolar cells type 1, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Fibroblasts_1"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			"CAB000043, HPA001060, HPA001338, HPA001383, HPA007983, CAB020416, CAB062555"	Enhanced		Enhanced	"Nucleoplasm,Plasma membrane,Cytosol"			NA	NA		360000	"Cluster 24: Non-specific - Transcription"	"Cluster 11: Esophagus - Basic cellular processes"	"Cluster 39: Astrocytes - Mixed function"	"Cluster 27: Breast cancer - Unknown function"	"Cluster 64: Renal epithelial cells - Ion transport & homeostasis"	202	"Plasma membrane"	"Nucleoplasm, Cytosol"	"CAB000043: , CAB020416: , CAB062555: , HPA001060: , HPA001338: , HPA001383: , HPA007983: "	"unprognostic (6.10e-2)"	"unprognostic (5.53e-2)"	"unprognostic (4.02e-2)"	"unprognostic (2.28e-1)"	"unprognostic (5.11e-3)"	"unprognostic (2.48e-1)"	"unprognostic (7.78e-2)"	"potential prognostic unfavorable (7.20e-5)"	"unprognostic (2.40e-2)"	"unprognostic (1.18e-1)"	"potential prognostic favorable (1.76e-8)"	"unprognostic (1.16e-3)"	"unprognostic (5.15e-3)"	"unprognostic (8.44e-2)"	"unprognostic (5.43e-2)"	"unprognostic (3.03e-1)"	"unprognostic (1.06e-2)"	"unprognostic (1.99e-1)"	"unprognostic (1.94e-1)"	"potential prognostic unfavorable (6.98e-4)"	"unprognostic (5.27e-1)"	"potential prognostic unfavorable (6.95e-4)"	"unprognostic (1.50e-1)"	"unprognostic (1.40e-1)"	"unprognostic (1.56e-2)"	"unprognostic (1.78e-1)"	"unprognostic (2.07e-2)"	"unprognostic (8.31e-2)"	"unprognostic (2.00e-1)"	"unprognostic (1.04e-1)"	"unprognostic (1.76e-1)"
FLT3	"CD135, FLK2, STK1"	ENSG00000122025	"Fms related receptor tyrosine kinase 3"	P36888	13	28003274-28100592	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, RAS pathway related proteins"	"Host-virus interaction"	"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in some"		"bone marrow: 5.0;brain: 8.9;lymphoid tissue: 6.1"	"Cell type enhanced"	"Detected in many"		"cDC: 332.1;Hematopoietic stem cells: 850.1;Megakaryocyte-Erythroid progenitors: 150.0;Monocyte progenitors: 515.2;monocytes: 176.2;Neutrophils: 137.9;pDCs: 172.6;Thymocytes: 597.1"	"Cell type enhanced"	"Detected in many"		"lower rhombic lip: 79.5;MGE interneuron: 94.6;upper rhombic lip: 84.5"	"Cancer enhanced"	"Detected in single"		"Breast Invasive Carcinoma (TCGA): 2.5"	"Region enhanced"	"Detected in many"		"cerebellum: 10.7"	"Group enriched"	"Detected in many"	13	"myeloid DC: 68.7;plasmacytoid DC: 26.3"	"Lineage enriched"	"Detected in many"	19	"dendritic cells: 68.7"	"Cancer enriched"	"Detected in single"	67	"Leukemia: 28.4"	"Adrenal gland - Macrophages, Prostate - Macrophages, Spleen - Neutrophils_2, Testis - Late spermatids"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA047539			Approved	"Endoplasmic reticulum"			NA	NA		160000	"Cluster 2: Dendritic cells - Unknown function"	"Cluster 61: Non-specific - Transcription"	"Cluster 25: Non-specific - Transcription"	"Cluster 14: Myeloid leukemia - Innate immune response"	"Cluster 40: Monocytes & Neutrophils - Inflammatory signaling"	12	"Endoplasmic reticulum"		"HPA047539: "		"unprognostic (6.35e-3)"	"unprognostic (1.19e-2)"					"unprognostic (6.61e-2)"																							
GRIN2A	"GluN2A, NMDAR2A"	ENSG00000183454	"Glutamate ionotropic receptor NMDA type subunit 2A"	Q12879	16	9753404-10182928	"Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters"	"Ion transport, Transport"	"Ion channel, Ligand-gated ion channel, Receptor"	"Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enriched"	"Detected in some"	5	"brain: 15.1"	"Cell type enhanced"	"Detected in many"		"Brain excitatory neurons: 785.7;Brain inhibitory neurons: 509.2;Ependymal cells: 474.4;Epicardial cells: 175.1;Müller glia: 113.5;Oligodendrocytes: 136.6;Retinal amacrine cells: 358.5;Retinal ganglion cells: 386.3"	"Low cell type specificity"	"Detected in all"			"Cancer enhanced"	"Detected in some"		"Kidney Renal Clear Cell Carcinoma (TCGA): 2.0;Ovary Serous Cystadenocarcinoma (TCGA): 2.1"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Low cancer specificity"	"Detected in some"			"Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB022725, HPA050216"	Enhanced		Uncertain	"Endoplasmic reticulum,Vesicles"			NA	NA				"Cluster 10: Brain - Synaptic signal transduction"	"Cluster 53: Neurons - Mixed function"	"Cluster 11: Neuronal - Sensory perception"	"Cluster 35: Neurons - Synaptic function & neurogenesis"	15	"Endoplasmic reticulum"	Vesicles	"CAB022725: , HPA050216: "			"unprognostic (1.65e-1)"				"unprognostic (1.02e-1)"	"unprognostic (6.45e-2)"			"unprognostic (2.26e-1)"	"unprognostic (1.98e-2)"								"unprognostic (1.78e-1)"			"unprognostic (1.47e-1)"			"unprognostic (4.28e-2)"					
IL6ST	"CD130, GP130, IL-6RB, sGP130"	ENSG00000134352	"Interleukin 6 cytokine family signal transducer"	P40189	5	55935095-55995022	"Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins"	"Host-virus interaction"	Receptor	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Endometrial glandular cells: 1204.2;Microglia: 759.0;Platelets: 681.9"	"Cell type enhanced"	"Detected in all"		"central nervous system macrophage: 924.1"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"naive CD4 T-cell: 22.8"	"Lineage enriched"	"Detected in many"	5	"T-cells: 22.8"	"Low cancer specificity"	"Detected in all"			"Stomach - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA010558, CAB025784"	Approved		Supported	"Golgi apparatus,Plasma membrane"	"Secreted to blood"	Receptor	NA	NA		48000000	"Cluster 33: Non-specific - ATP binding"	"Cluster 43: Placenta - Pregnancy hormone signaling"	"Cluster 28: Oligodendrocytes - Mixed function"	"Cluster 64: Connective tissue cells - ECM organization"	"Cluster 51: Secretory epithelial cells - Mixed function"	22	"Plasma membrane"	"Golgi apparatus"	"CAB025784: , HPA010558: "	"unprognostic (3.34e-2)"	"unprognostic (9.54e-3)"	"unprognostic (6.35e-2)"	"unprognostic (4.58e-2)"	"unprognostic (3.44e-1)"	"unprognostic (5.93e-3)"	"unprognostic (1.49e-1)"	"potential prognostic unfavorable (3.79e-5)"	"unprognostic (1.62e-2)"	"unprognostic (1.27e-2)"	"potential prognostic favorable (3.47e-5)"	"unprognostic (6.75e-3)"	"unprognostic (1.20e-1)"	"unprognostic (7.66e-2)"	"unprognostic (2.13e-3)"	"unprognostic (4.31e-3)"	"unprognostic (2.61e-1)"	"unprognostic (5.52e-2)"	"unprognostic (2.62e-1)"	"unprognostic (2.74e-1)"	"unprognostic (5.83e-3)"	"unprognostic (1.16e-2)"	"unprognostic (4.67e-2)"	"unprognostic (7.33e-2)"	"unprognostic (6.47e-3)"	"unprognostic (1.68e-1)"	"unprognostic (2.75e-2)"	"unprognostic (5.11e-3)"	"unprognostic (4.99e-1)"	"unprognostic (3.20e-1)"	"unprognostic (1.40e-1)"
IL7R	"CD127, IL7RA, lnc-IL7R"	ENSG00000168685	"Interleukin 7 receptor"	P16871	5	35852695-35879603	"Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins"		Receptor	"Cancer-related genes, Disease variant, SCID"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"lymphoid tissue: 171.2"	"Group enriched"	"Detected in many"	5	"Innate lymphoid cells: 3240.4;T-cells: 1496.2"	"Cell type enriched"	"Detected in some"	115	"leukocyte: 454.7"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	4	"gdT-cell: 102.3;MAIT T-cell: 370.2;memory CD4 T-cell: 214.4;memory CD8 T-cell: 151.1;naive CD4 T-cell: 180.0;naive CD8 T-cell: 125.1;NK-cell: 113.4"	"Group enriched"	"Detected in all"	34	"NK-cells: 113.4;T-cells: 370.2"	"Low cancer specificity"	"Detected in many"			"Adipose subcutaneous - T-cells, Colon - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"CAB010215, HPA067550, CAB080603"	Supported		Supported	"Plasma membrane"	"Intracellular and membrane"	Receptor	NA	NA		290000	"Cluster 27: T-cells - Unknown function"	"Cluster 51: Lymphoid tissue - Adaptive immune response"	"Cluster 48: Non-specific - Mixed function"	"Cluster 6: Leukemia - Signal transduction"	"Cluster 9: T-cells - Adaptive immunity: Regulation"	13	"Plasma membrane"		"CAB010215: , CAB080603: , HPA067550: "	"unprognostic (2.81e-1)"	"unprognostic (5.36e-3)"	"unprognostic (4.45e-2)"	"unprognostic (6.91e-2)"	"unprognostic (9.97e-2)"	"unprognostic (3.73e-1)"	"unprognostic (3.58e-2)"	"unprognostic (1.17e-2)"	"unprognostic (2.53e-1)"	"unprognostic (1.38e-1)"	"unprognostic (1.25e-1)"	"unprognostic (1.04e-2)"	"unprognostic (1.22e-1)"	"unprognostic (6.18e-3)"	"unprognostic (2.22e-2)"	"unprognostic (2.20e-3)"	"unprognostic (6.89e-2)"	"unprognostic (6.82e-2)"	"unprognostic (1.79e-1)"	"unprognostic (8.32e-3)"	"unprognostic (2.31e-1)"	"unprognostic (1.92e-1)"	"unprognostic (1.94e-2)"	"unprognostic (3.92e-1)"	"unprognostic (1.72e-2)"	"unprognostic (2.01e-1)"	"unprognostic (1.22e-1)"	"unprognostic (1.68e-2)"	"unprognostic (2.03e-2)"	"unprognostic (8.41e-2)"	"unprognostic (5.78e-2)"
JAK2	JTK10	ENSG00000096968	"Janus kinase 2"	O60674	9	4984390-5129948	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Adaptive immunity, Immunity, Innate immunity"	"Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Microglia: 371.0;Myonuclei: 421.3;Neutrophil progenitors: 438.8;Neutrophils: 666.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in all"		"basophil: 133.0"	"Lineage enriched"	"Detected in all"	5	"granulocytes: 133.0"	"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB013089, HPA040820, HPA043870"	Approved		Supported	"Nucleoplasm,Plasma membrane,Focal adhesion sites"			No	No			"Cluster 46: Basophils - Proteolysis"	"Cluster 12: Smooth muscle tissue - ECM organization"	"Cluster 53: Neurons - Mixed function"	"Cluster 47: Leukemia - Hemostasis"	"Cluster 48: Neutrophils - Phagocytosis & degranulation"	44	Nucleoplasm	"Plasma membrane, Focal adhesion sites"	"CAB013089: , HPA040820: , HPA043870: "	"unprognostic (2.70e-2)"	"unprognostic (5.40e-3)"	"unprognostic (1.83e-1)"	"unprognostic (2.05e-1)"	"unprognostic (3.78e-2)"	"unprognostic (2.35e-1)"	"unprognostic (1.42e-1)"	"unprognostic (1.00e-1)"	"unprognostic (6.81e-3)"	"unprognostic (2.82e-2)"	"potential prognostic favorable (1.07e-4)"	"unprognostic (1.09e-1)"	"unprognostic (2.43e-3)"	"unprognostic (2.89e-1)"	"unprognostic (3.10e-2)"	"unprognostic (1.21e-2)"	"unprognostic (9.70e-2)"	"unprognostic (9.49e-2)"	"unprognostic (2.15e-1)"	"unprognostic (6.38e-3)"	"unprognostic (7.43e-2)"	"unprognostic (1.49e-1)"	"unprognostic (5.42e-2)"	"unprognostic (3.80e-2)"	"unprognostic (8.10e-3)"	"unprognostic (4.82e-2)"	"unprognostic (5.27e-2)"	"unprognostic (2.30e-2)"	"unprognostic (1.77e-1)"	"unprognostic (5.43e-2)"	"unprognostic (9.78e-3)"
KIT	"C-Kit, CD117, PBT, SCFR"	ENSG00000157404	"KIT proto-oncogene, receptor tyrosine kinase"	P10721	4	54657267-54740783	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"		"Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"breast: 79.2"	"Cell type enhanced"	"Detected in many"		"Breast secretory cells: 230.0;Innate lymphoid cells: 512.9;Mast cells: 1765.7;Melanocytes: 649.5;Renal collecting duct intercalated cells: 569.2;Respiratory ionocytes: 396.2;Salivary ionocytes: 263.8;Tuft cells: 253.6"	"Cell type enhanced"	"Detected in many"		"cerebellar inhibitory: 699.5;CGE interneuron: 325.6;midbrain-derived inhibitory: 571.8"	"Cancer enhanced"	"Detected in many"		"Kidney Chromophobe (TCGA): 143.8"	"Low region specificity"	"Detected in all"			"Group enriched"	"Detected in many"	6	"basophil: 16.1;eosinophil: 9.6;NK-cell: 11.1"	"Group enriched"	"Detected in many"	7	"granulocytes: 16.1;NK-cells: 11.1"	"Cancer enhanced"	"Detected in many"		"Leukemia: 28.3"	"Adipose subcutaneous - Mast cells, Lung - Mast cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB003288, HPA004471, CAB068253, CAB072867, HPA073252"	Enhanced	Supported	Supported	"Nucleoli fibrillar center,Plasma membrane"			NA	NA		33000000	"Cluster 32: Basophils - Transcription"	"Cluster 55: Breast - Lactation"	"Cluster 35: Non-specific - DNA binding"	"Cluster 49: HMC-1 - Innate immune response"	"Cluster 58: Mast cells - Allergic inflammatory responses"	42	"Plasma membrane"	"Nucleoli fibrillar center"	"CAB003288: , CAB068253: , CAB072867: , HPA004471: , HPA073252: "	"unprognostic (7.25e-2)"	"unprognostic (1.24e-2)"	"unprognostic (1.08e-1)"	"unprognostic (3.57e-1)"	"unprognostic (2.82e-1)"	"unprognostic (4.48e-2)"	"unprognostic (1.51e-1)"	"unprognostic (1.08e-1)"	"unprognostic (4.25e-2)"	"unprognostic (1.60e-1)"	"validated prognostic favorable (7.36e-5)"	"validated prognostic favorable (6.08e-5)"	"unprognostic (2.94e-1)"		"unprognostic (7.19e-3)"	"unprognostic (2.19e-3)"	"unprognostic (1.04e-2)"	"unprognostic (3.27e-2)"	"unprognostic (1.38e-1)"			"unprognostic (2.74e-1)"	"unprognostic (1.04e-1)"	"unprognostic (9.24e-2)"	"potential prognostic favorable (3.33e-4)"	"unprognostic (1.39e-2)"	"unprognostic (8.07e-2)"	"unprognostic (2.38e-3)"	"unprognostic (7.41e-2)"	"unprognostic (1.10e-2)"	"unprognostic (3.71e-1)"
KMT2A	"ALL-1, ALL1, CXXC7, HRX, HTRX, HTRX1, MLL, MLL1, MLL1A, TRX1"	ENSG00000118058	"Lysine methyltransferase 2A"	Q03164	11	118436456-118526832	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors"	"Apoptosis, Biological rhythms, Host-virus interaction, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Methyltransferase, Transferase"	"Cancer-related genes, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in many"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB017794, CAB024270, HPA044910"	Enhanced		Supported	Nucleoplasm,Cytosol			NA	NA			"Cluster 24: Non-specific - Transcription"	"Cluster 32: Retina & Lymphoid tissues - Signaling"	"Cluster 16: Non-specific - Transcription"	"Cluster 24: Non-specific - Unknown function"	"Cluster 102: Non-specific - Mixed function"	111	Nucleoplasm	Cytosol	"CAB017794: , CAB024270: , HPA044910: "	"unprognostic (4.14e-2)"	"unprognostic (6.50e-2)"		"unprognostic (2.12e-2)"	"unprognostic (2.79e-1)"	"unprognostic (1.30e-2)"	"unprognostic (3.60e-2)"	"unprognostic (1.95e-3)"	"unprognostic (1.67e-2)"	"unprognostic (1.78e-2)"	"validated prognostic favorable (2.17e-5)"	"validated prognostic favorable (1.46e-4)"	"unprognostic (1.10e-1)"	"unprognostic (2.45e-2)"		"unprognostic (4.63e-1)"	"unprognostic (1.14e-2)"	"unprognostic (3.90e-2)"	"unprognostic (2.35e-1)"	"unprognostic (2.85e-2)"	"unprognostic (1.83e-1)"	"unprognostic (3.07e-1)"	"unprognostic (1.03e-2)"	"unprognostic (3.08e-1)"	"unprognostic (2.74e-3)"	"unprognostic (5.57e-3)"	"unprognostic (2.51e-1)"	"unprognostic (7.33e-2)"	"unprognostic (3.06e-1)"	"unprognostic (4.48e-2)"	"unprognostic (3.83e-1)"
MAP3K1	"MAPKKK1, MEKK, MEKK1"	ENSG00000095015	"Mitogen-activated protein kinase kinase kinase 1"	Q13233	5	56815549-56896152	"Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins"		"Kinase, Serine/threonine-protein kinase, Transferase"	"Cancer-related genes, FDA approved drug targets"	"Evidence at protein level"	"Evidence at transcript level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"B-cells: 303.0;Neutrophils: 414.6"	"Cell type enhanced"	"Detected in all"		"oligodendrocyte precursor cell: 299.8"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Region enriched"	"Detected in all"	6	"olfactory bulb: 18.2"	"Low region specificity"	"Detected in all"			"CAB004500, HPA046509"	Approved		Approved	Cytosol			NA	NA			"Cluster 40: Monocytes - Innate immune response"	"Cluster 40: Non-specific - Mixed function"	"Cluster 42: Choroid plexus - Mitochondria"	"Cluster 6: Leukemia - Signal transduction"	"Cluster 24: Neutrophils - Innate immunity signal integration"	45	Cytosol		"CAB004500: , HPA046509: "	"unprognostic (4.13e-2)"	"unprognostic (9.22e-2)"	"unprognostic (2.94e-1)"	"unprognostic (6.21e-2)"	"unprognostic (1.05e-1)"	"unprognostic (2.73e-3)"	"unprognostic (9.47e-2)"	"unprognostic (2.08e-1)"	"unprognostic (3.11e-3)"	"unprognostic (6.12e-2)"	"validated prognostic favorable (2.68e-8)"	"validated prognostic favorable (6.14e-5)"	"unprognostic (2.05e-1)"	"unprognostic (1.46e-1)"	"unprognostic (2.11e-1)"	"unprognostic (4.01e-2)"	"unprognostic (1.61e-1)"	"unprognostic (5.47e-2)"	"unprognostic (5.97e-2)"	"unprognostic (1.56e-2)"	"unprognostic (1.50e-1)"	"unprognostic (2.11e-2)"	"unprognostic (1.08e-1)"	"unprognostic (1.14e-1)"	"unprognostic (2.93e-2)"	"unprognostic (9.05e-2)"	"unprognostic (2.53e-1)"	"unprognostic (2.05e-1)"	"unprognostic (3.91e-1)"	"unprognostic (3.50e-2)"	"unprognostic (1.58e-1)"
MED12	"ARC240, CAGH45, FGS1, HOPA, KIAA0192, Kto, OKS, OPA1, TNRC11, TRAP230"	ENSG00000184634	"Mediator complex subunit 12"	Q93074	X	71118543-71144103	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Transcription, Transcription regulation"	"Activator, Repressor"	"Cancer-related genes, Disease variant, Intellectual disability"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Neutrophils: 54.6"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003184, HPA003185"	Enhanced		Approved	Nucleoplasm			NA	NA			"Cluster 33: Non-specific - ATP binding"	"Cluster 4: Adrenal gland - Steroid metabolism"	"Cluster 43: Hindbrain - Mixed function"	"Cluster 36: Non-specific - mRNA processing"	"Cluster 48: Neutrophils - Phagocytosis & degranulation"	86	Nucleoplasm		"HPA003184: , HPA003185: "	"unprognostic (5.92e-2)"	"unprognostic (4.88e-3)"	"unprognostic (4.13e-2)"	"unprognostic (6.89e-2)"	"unprognostic (1.00e-1)"	"unprognostic (1.04e-1)"	"unprognostic (3.19e-2)"	"unprognostic (7.55e-2)"	"unprognostic (1.12e-1)"	"unprognostic (2.01e-2)"	"unprognostic (2.93e-1)"	"unprognostic (9.58e-2)"	"unprognostic (1.41e-1)"	"unprognostic (8.16e-3)"	"unprognostic (1.73e-1)"	"unprognostic (2.59e-2)"	"unprognostic (3.92e-3)"	"unprognostic (4.78e-2)"	"unprognostic (1.78e-2)"	"unprognostic (1.54e-1)"	"unprognostic (2.19e-2)"	"unprognostic (2.46e-1)"	"unprognostic (1.39e-1)"	"unprognostic (1.50e-1)"	"unprognostic (3.06e-1)"	"unprognostic (4.41e-3)"	"unprognostic (1.33e-1)"	"unprognostic (2.09e-1)"	"unprognostic (5.36e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.08e-2)"
NCOR1	"hCIT529I10, hN-CoR, KIAA1047, MGC104216, N-CoR, PPP1R109, TRAC1"	ENSG00000141027	"Nuclear receptor corepressor 1"	O75376	17	16029065-16218185	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Biological rhythms, Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Liver - Hepatocytes"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA043246, HPA050288, HPA051168, CAB072830"	Supported		Approved	Nucleoplasm,Cytosol			NA	NA			"Cluster 32: Basophils - Transcription"	"Cluster 76: Non-specific - Metabolism"	"Cluster 16: Non-specific - Transcription"	"Cluster 42: Non-specific - Unknown function"	"Cluster 48: Neutrophils - Phagocytosis & degranulation"	128	Nucleoplasm	Cytosol	"CAB072830: , HPA043246: , HPA050288: , HPA051168: "	"unprognostic (1.08e-1)"	"unprognostic (8.02e-2)"	"unprognostic (1.64e-1)"	"unprognostic (1.13e-1)"	"unprognostic (5.09e-2)"	"unprognostic (3.00e-2)"	"unprognostic (5.02e-2)"	"unprognostic (3.30e-2)"	"unprognostic (4.49e-2)"	"unprognostic (7.67e-3)"	"validated prognostic favorable (7.87e-9)"	"validated prognostic favorable (4.87e-4)"	"unprognostic (1.28e-1)"	"unprognostic (1.34e-1)"	"unprognostic (2.18e-1)"	"unprognostic (1.30e-1)"	"unprognostic (1.52e-1)"	"unprognostic (2.62e-2)"	"unprognostic (4.86e-2)"	"unprognostic (1.82e-1)"	"unprognostic (4.08e-2)"	"unprognostic (6.60e-3)"	"unprognostic (2.60e-2)"	"unprognostic (1.21e-1)"	"unprognostic (3.60e-2)"	"unprognostic (1.89e-1)"	"unprognostic (2.65e-2)"	"unprognostic (1.74e-2)"	"unprognostic (2.60e-1)"	"unprognostic (9.59e-2)"	"unprognostic (1.17e-1)"
NCOR2	"CTG26, SMRT, SMRTE, TNRC14, TRAC-1"	ENSG00000196498	"Nuclear receptor corepressor 2"	Q9Y618	12	124324415-124567612	"Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"DNA-binding, Repressor"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in some"		"basophil: 6.1"	"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA001928	Approved		Supported	Nucleoplasm			NA	NA			"Cluster 22: Eosinophils - Transcription"	"Cluster 24: Non-specific - Transcription"	"Cluster 32: Cerebral cortex - Mixed function"	"Cluster 38: Non-specific - Transcription"	"Cluster 40: Monocytes & Neutrophils - Inflammatory signaling"	100	Nucleoplasm		"HPA001928: "	"unprognostic (8.84e-2)"	"unprognostic (8.65e-2)"	"unprognostic (8.05e-2)"	"potential prognostic unfavorable (3.73e-4)"	"unprognostic (1.84e-1)"	"unprognostic (6.34e-3)"	"unprognostic (9.51e-2)"	"unprognostic (1.62e-1)"	"unprognostic (8.22e-2)"	"unprognostic (4.02e-2)"	"unprognostic (8.99e-2)"	"unprognostic (3.23e-2)"	"unprognostic (3.88e-1)"	"unprognostic (2.28e-2)"	"unprognostic (1.31e-1)"	"unprognostic (5.78e-2)"	"unprognostic (2.22e-2)"	"unprognostic (6.34e-2)"	"unprognostic (2.90e-1)"	"unprognostic (1.02e-3)"	"unprognostic (2.02e-1)"	"unprognostic (7.74e-3)"	"unprognostic (6.10e-3)"	"unprognostic (1.94e-1)"	"unprognostic (4.98e-2)"	"unprognostic (2.89e-3)"	"unprognostic (3.08e-2)"	"unprognostic (2.80e-2)"	"unprognostic (2.65e-1)"	"unprognostic (1.90e-2)"	"unprognostic (1.83e-1)"
NF1		ENSG00000196712	"Neurofibromin 1"	P21359	17	31094927-31382116	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"		"GTPase activation"	"Cancer-related genes, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA045502, HPA075627, CAB080363, CAB080365"	Uncertain		Supported	"Nucleoplasm,Plasma membrane,Microtubules"			NA	No			"Cluster 5: Non-specific - Cell proliferation"	"Cluster 61: Non-specific - Transcription"	"Cluster 34: Non-specific - Mixed function"	"Cluster 27: Breast cancer - Unknown function"	"Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis"	25	"Plasma membrane"	"Nucleoplasm, Microtubules"	"CAB080363: , CAB080365: , HPA045502: , HPA075627: "	"unprognostic (1.75e-1)"	"unprognostic (4.11e-2)"	"unprognostic (2.46e-1)"	"unprognostic (4.14e-3)"	"unprognostic (6.12e-2)"	"unprognostic (1.98e-1)"	"unprognostic (2.38e-2)"	"unprognostic (1.38e-1)"	"unprognostic (5.80e-2)"	"unprognostic (1.44e-2)"	"potential prognostic favorable (2.97e-4)"	"unprognostic (1.54e-2)"	"unprognostic (1.82e-1)"	"unprognostic (1.46e-1)"	"unprognostic (2.67e-2)"	"unprognostic (6.20e-2)"	"unprognostic (4.16e-2)"	"unprognostic (1.35e-1)"	"unprognostic (1.37e-2)"	"unprognostic (1.65e-2)"	"unprognostic (7.41e-2)"	"unprognostic (1.17e-2)"	"unprognostic (2.53e-3)"	"unprognostic (6.64e-2)"	"unprognostic (6.89e-3)"	"unprognostic (5.77e-2)"	"unprognostic (1.63e-1)"	"unprognostic (6.77e-2)"	"unprognostic (1.90e-1)"	"unprognostic (5.34e-2)"	"unprognostic (1.19e-1)"
NF2	"ACN, BANF, merlin, merlin-1, SCH"	ENSG00000186575	"NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor"	P35240	22	29603556-29698598	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins"			"Cancer-related genes, Deafness, Disease variant, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Late spermatids: 176.3"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA003097, CAB005385"	Supported		Enhanced	"Nucleoplasm,Plasma membrane,Cytosol"			NA	NA			"Cluster 33: Non-specific - ATP binding"	"Cluster 52: Non-specific - Cellular respiration"	"Cluster 32: Cerebral cortex - Mixed function"	"Cluster 15: Kidney cancer - Membrane components"	"Cluster 17: Non-specific - RNA processing"	64	"Plasma membrane"	"Nucleoplasm, Cytosol"	"CAB005385: , HPA003097: "	"unprognostic (4.47e-1)"	"unprognostic (1.10e-1)"	"unprognostic (9.08e-2)"	"unprognostic (1.45e-1)"	"unprognostic (1.60e-2)"	"unprognostic (3.34e-1)"	"unprognostic (2.26e-1)"	"unprognostic (1.17e-2)"	"unprognostic (1.60e-1)"	"unprognostic (9.40e-2)"	"potential prognostic favorable (5.60e-4)"	"unprognostic (4.02e-3)"	"potential prognostic favorable (1.21e-4)"	"unprognostic (3.49e-3)"	"unprognostic (4.81e-2)"	"unprognostic (2.10e-1)"	"unprognostic (7.44e-2)"	"unprognostic (1.16e-1)"	"unprognostic (1.47e-2)"	"unprognostic (1.18e-2)"	"unprognostic (2.69e-1)"	"unprognostic (1.91e-2)"	"unprognostic (1.43e-2)"	"unprognostic (4.09e-1)"	"unprognostic (3.27e-2)"	"unprognostic (1.23e-1)"	"unprognostic (1.82e-1)"	"unprognostic (6.50e-2)"	"unprognostic (2.89e-1)"	"unprognostic (5.13e-2)"	"unprognostic (2.83e-1)"
NOTCH1	TAN1	ENSG00000148400	"Notch receptor 1"	P46531	9	136494433-136546048	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters"	"Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation"	"Activator, Developmental protein, Receptor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Astrocytes: 77.3;Lymphatic endothelial cells: 92.8;Müller glia: 83.5;Neutrophils: 213.5;Vascular endothelial cells: 83.3"	"Cell type enhanced"	"Detected in many"		"astrocyte: 88.9;endothelial cell: 116.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in single"		"neutrophil: 2.3"	"Low lineage specificity"	"Detected in single"			"Low cancer specificity"	"Detected in many"			"Adrenal gland - Endothelial cells, Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB008112, CAB022466, HPA067168"	Supported		Approved	Nucleoplasm			NA	NA		9900000	"Cluster 21: Neutrophils - Unknown function"	"Cluster 2: Non-specific - Mixed function"	"Cluster 19: Astrocytes - Mixed function"	"Cluster 59: Leukemia - T-cell receptor"	"Cluster 24: Neutrophils - Innate immunity signal integration"	107	Nucleoplasm		"CAB008112: , CAB022466: , HPA067168: "	"unprognostic (7.30e-2)"	"unprognostic (1.75e-1)"	"unprognostic (2.05e-1)"	"unprognostic (2.39e-2)"	"unprognostic (2.70e-1)"	"unprognostic (1.46e-1)"	"unprognostic (1.50e-1)"	"unprognostic (2.24e-3)"	"unprognostic (1.00e-1)"	"unprognostic (1.44e-1)"	"validated prognostic favorable (9.19e-6)"	"validated prognostic favorable (4.90e-4)"	"potential prognostic unfavorable (2.84e-4)"	"unprognostic (1.74e-1)"	"unprognostic (1.24e-3)"	"unprognostic (1.48e-1)"		"unprognostic (7.15e-3)"	"unprognostic (1.83e-2)"	"unprognostic (4.29e-2)"	"unprognostic (1.90e-1)"	"unprognostic (2.34e-2)"	"unprognostic (2.91e-1)"	"unprognostic (3.86e-2)"	"unprognostic (2.76e-2)"	"unprognostic (7.28e-2)"	"unprognostic (1.32e-1)"	"unprognostic (5.40e-2)"	"unprognostic (9.44e-2)"	"unprognostic (4.00e-3)"	"unprognostic (1.58e-1)"
PBRM1	"BAF180, PB1, SMARCH1"	ENSG00000163939	"Polybromo 1"	Q86U86	3	52545352-52685917	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Chromatin regulator, DNA-binding"	"Cancer-related genes, Tumor suppressor"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"				"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA015629, HPA059373"	Uncertain		Enhanced	Nucleoplasm			NA	NA			"Cluster 22: Eosinophils - Transcription"	"Cluster 61: Non-specific - Transcription"	"Cluster 50: Non-specific - Nucleic acid binding"	"Cluster 8: Non-specific - Basic cellular processes"	"Cluster 7: Non-specific - Transcription"	36	Nucleoplasm		"HPA015629: , HPA059373: "	"unprognostic (7.51e-3)"	"unprognostic (1.60e-1)"	"unprognostic (7.01e-2)"	"unprognostic (6.06e-2)"	"unprognostic (1.77e-1)"	"unprognostic (1.94e-1)"	"unprognostic (8.45e-2)"	"unprognostic (2.81e-2)"	"unprognostic (6.75e-3)"	"unprognostic (1.07e-2)"	"potential prognostic favorable (2.75e-5)"	"unprognostic (2.08e-2)"	"unprognostic (1.16e-1)"	"unprognostic (2.78e-3)"	"unprognostic (5.08e-2)"	"unprognostic (6.94e-2)"	"unprognostic (1.05e-1)"	"unprognostic (1.21e-1)"	"unprognostic (2.30e-1)"	"unprognostic (1.40e-1)"	"unprognostic (3.92e-3)"	"unprognostic (6.22e-2)"	"unprognostic (1.14e-1)"	"unprognostic (1.26e-1)"	"unprognostic (4.57e-3)"	"unprognostic (8.94e-2)"	"unprognostic (6.36e-2)"	"unprognostic (1.24e-1)"	"unprognostic (2.86e-1)"	"unprognostic (1.40e-2)"	"unprognostic (1.81e-1)"
PDGFRA	"CD140a, GAS9, PDGFR2"	ENSG00000134853	"Platelet derived growth factor receptor alpha"	P16234	4	54229280-54298245	"Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins"	"Chemotaxis, Host-virus interaction"	"Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase"	"Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in all"		"ovary: 188.3"	"Group enriched"	"Detected in many"	4	"Decidual stromal cells: 203.7;Endometrial stromal cells: 261.4;Fibroblasts: 245.6;Hepatic stellate cells: 154.9;Leydig cells: 301.5;Oligodendrocyte progenitor cells: 296.2;Ovarian stromal cells: 108.6;Peritubular myoid cells: 333.9"	"Group enriched"	"Detected in some"	13	"fibroblast: 133.8;oligodendrocyte precursor cell: 320.9"	"Cancer enhanced"	"Detected in all"		"Glioblastoma Multiforme (TCGA): 101.1"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Rhabdoid: 78.7;thyroid cancer: 38.5"	"Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Macrophages, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA004947, CAB018143"	Supported		Approved	"Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions,Primary cilium,Cytosol"	"Intracellular and membrane"	Receptor	NA	NA		310000		"Cluster 75: Ovary - Mixed function"	"Cluster 20: Macrophages & Microglia - Immune response"	"Cluster 44: Connective tissue cells - ECM organization"	"Cluster 108: Fibroblasts - ECM organization"	36	"Nucleoplasm, Plasma membrane, Cell Junctions"	"Nuclear bodies, Primary cilium, Cytosol"	"CAB018143: , HPA004947: "	"unprognostic (1.39e-1)"	"unprognostic (2.75e-1)"	"unprognostic (4.29e-1)"	"unprognostic (3.15e-2)"	"unprognostic (5.76e-2)"	"unprognostic (9.07e-2)"	"unprognostic (3.95e-1)"	"unprognostic (8.34e-3)"	"potential prognostic favorable (6.22e-5)"	"unprognostic (2.31e-1)"	"unprognostic (3.55e-2)"	"unprognostic (3.37e-1)"	"unprognostic (1.09e-3)"	"unprognostic (7.37e-2)"	"unprognostic (4.97e-3)"	"unprognostic (1.86e-1)"	"unprognostic (2.27e-1)"	"unprognostic (1.51e-2)"	"unprognostic (1.12e-1)"	"unprognostic (1.17e-2)"	"unprognostic (3.70e-3)"	"unprognostic (9.86e-2)"	"unprognostic (6.95e-2)"	"unprognostic (8.35e-2)"	"unprognostic (2.92e-1)"	"unprognostic (3.93e-2)"	"unprognostic (1.56e-2)"	"unprognostic (6.53e-3)"	"unprognostic (3.89e-2)"	"unprognostic (1.59e-2)"	"unprognostic (3.22e-2)"
PIK3R1	"GRB1, p85, p85-ALPHA"	ENSG00000145675	"Phosphoinositide-3-kinase regulatory subunit 1"	P27986	5	68215740-68301821	"Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins"	"Host-virus interaction, Protein transport, Stress response, Transport"	"GTPase activation"	"Cancer-related genes, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"NK-cells: 628.4;Oligodendrocyte progenitor cells: 578.8;Schwann cells: 570.8;Thymic myoid cells: 775.0"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Adrenal gland - Fibroblasts, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001216, CAB004268"	Approved		Approved	Cytosol			NA	NA			"Cluster 3: Non-specific - Nuclear processes"	"Cluster 63: Non-specific - Basic cellular processes"	"Cluster 53: Neurons - Mixed function"	"Cluster 44: Connective tissue cells - ECM organization"	"Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity"	190	Cytosol		"CAB004268: , HPA001216: "	"unprognostic (5.44e-3)"	"unprognostic (4.41e-2)"	"unprognostic (2.62e-1)"	"unprognostic (7.67e-2)"	"unprognostic (1.39e-1)"	"unprognostic (2.04e-1)"	"unprognostic (2.37e-1)"	"unprognostic (3.12e-2)"	"unprognostic (1.06e-2)"	"unprognostic (7.24e-3)"	"potential prognostic favorable (5.75e-6)"	"unprognostic (2.46e-3)"	"unprognostic (1.16e-1)"	"unprognostic (7.80e-3)"	"potential prognostic favorable (2.14e-4)"	"potential prognostic favorable (2.08e-4)"	"unprognostic (5.59e-2)"	"unprognostic (1.59e-1)"	"unprognostic (1.35e-1)"	"unprognostic (2.26e-1)"	"unprognostic (6.40e-3)"	"unprognostic (8.92e-2)"	"unprognostic (1.32e-1)"	"unprognostic (3.27e-1)"	"unprognostic (1.58e-1)"	"unprognostic (6.19e-2)"	"unprognostic (1.49e-1)"	"unprognostic (3.76e-3)"	"unprognostic (1.29e-1)"	"unprognostic (8.97e-2)"	"unprognostic (7.94e-2)"
RHOA	"ARH12, ARHA, Rho12, RHOH12"	ENSG00000067560	"Ras homolog family member A"	P61586	3	49359139-49412998	"Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins"	"Cell cycle, Cell division, Host-virus interaction"	Hydrolase	"Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in many"		"Cardiomyocytes: 98.6;Choroid plexus epithelial cells: 53.5;Distal convoluted tubule cells: 66.0;Ependymal cells: 58.8;Loop of henle epithelial cells: 78.0;Microglia: 107.5;Oligodendrocytes: 77.0;Other brain neurons: 52.2;Papillary tip epithelial cells: 95.2;Podocytes: 78.2;Proximal tubule cells: 65.3;Renal collecting duct intercalated cells: 84.0;Renal collecting duct principal cells: 77.7;Renal connecting tubule cells: 87.5"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Spleen - Macrophages"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			CAB005052	Approved		Supported	"Plasma membrane,Cytosol"			NA	NA		1600000	"Cluster 38: Monocytes & Neutrophils - Degranulation"	"Cluster 12: Smooth muscle tissue - ECM organization"	"Cluster 28: Oligodendrocytes - Mixed function"	"Cluster 8: Non-specific - Basic cellular processes"	"Cluster 102: Non-specific - Mixed function"	188	"Plasma membrane, Cytosol"		"CAB005052: "	"unprognostic (3.25e-2)"	"unprognostic (9.84e-2)"	"unprognostic (3.95e-1)"	"unprognostic (8.00e-2)"	"unprognostic (2.18e-2)"	"unprognostic (3.32e-1)"	"unprognostic (2.57e-1)"	"unprognostic (6.23e-2)"	"unprognostic (2.10e-1)"	"potential prognostic unfavorable (2.40e-4)"	"potential prognostic favorable (2.75e-7)"	"unprognostic (9.18e-3)"	"potential prognostic favorable (3.33e-4)"	"validated prognostic unfavorable (2.85e-4)"	"validated prognostic unfavorable (2.59e-4)"	"unprognostic (1.05e-1)"	"unprognostic (1.53e-3)"	"unprognostic (8.79e-2)"	"unprognostic (2.55e-2)"	"unprognostic (1.25e-2)"	"unprognostic (1.12e-1)"	"unprognostic (8.62e-3)"	"unprognostic (7.88e-2)"	"unprognostic (1.68e-1)"	"unprognostic (7.61e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.07e-1)"	"unprognostic (7.86e-2)"	"unprognostic (2.56e-1)"	"unprognostic (1.48e-1)"	"unprognostic (1.55e-2)"
SBDS	"CGI-97, FLJ10917, SDO1, SDS, SWDS"	ENSG00000126524	"SBDS ribosome maturation factor"	Q9Y3A5	7	66987680-66995693	"Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins"	"Ribosome biogenesis"		"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Early spermatids: 699.4;Esophageal apical cells: 765.9;Late spermatids: 2814.4"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			HPA028891	Approved		Supported	Nucleoplasm,Cytosol			NA	NA		18000	"Cluster 3: Non-specific - Nuclear processes"	"Cluster 25: Non-specific - Basic cellular processes"	"Cluster 28: Oligodendrocytes - Mixed function"	"Cluster 39: Non-specific - Transcription"	"Cluster 73: Late spermatids - Spermiogenesis: Maturation"	41	Cytosol	Nucleoplasm	"HPA028891: "	"unprognostic (1.53e-1)"	"potential prognostic unfavorable (1.82e-4)"	"unprognostic (1.83e-1)"	"unprognostic (8.71e-2)"	"unprognostic (6.69e-2)"	"unprognostic (9.18e-2)"	"unprognostic (5.26e-2)"	"potential prognostic unfavorable (5.67e-5)"	"unprognostic (3.34e-3)"	"unprognostic (3.14e-2)"	"validated prognostic favorable (7.98e-7)"	"validated prognostic favorable (6.53e-4)"	"unprognostic (1.61e-1)"	"unprognostic (1.66e-1)"	"unprognostic (1.53e-2)"	"unprognostic (9.68e-3)"	"unprognostic (9.82e-2)"	"unprognostic (2.35e-1)"	"unprognostic (5.33e-3)"	"unprognostic (4.36e-3)"	"unprognostic (5.95e-2)"	"unprognostic (9.73e-2)"	"unprognostic (1.60e-1)"	"unprognostic (2.46e-1)"	"unprognostic (9.09e-2)"	"unprognostic (2.14e-1)"	"unprognostic (1.18e-1)"	"unprognostic (2.42e-3)"	"unprognostic (1.41e-1)"	"unprognostic (1.14e-1)"	"unprognostic (9.21e-2)"
SOCS1	"Cish1, JAB, SOCS-1, SSI-1, TIP3"	ENSG00000185338	"Suppressor of cytokine signaling 1"	O15524	16	11254417-11256204	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins"	"Growth regulation, Ubl conjugation pathway"	"Signal transduction inhibitor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in many"			"Cell type enhanced"	"Detected in many"		"Breast lactating cells: 91.1;Early spermatids: 85.6;Epididymal basal cells: 139.7;Innate lymphoid cells: 179.2;Mast cells: 265.4;NK-cells: 133.3;Pancreatic islet cells: 182.5;Syncytiotrophoblasts: 85.1;T-cells: 137.2"	"Cell type enriched"	"Detected in many"	4	"leukocyte: 41.0"	"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Immune cell enhanced"	"Detected in many"		"basophil: 13.8"	"Low lineage specificity"	"Detected in many"			"Cancer enhanced"	"Detected in many"		"lymphoma: 22.6"	"Liver - Neutrophils"	"Not detected"	"Not detected"			"Low region specificity"	"Detected in single"			"CAB010355, HPA074108"	Approved		Supported	Nucleoplasm,Vesicles			NA	NA			"Cluster 22: Eosinophils - Transcription"	"Cluster 66: Lymphoid tissue - Immune response"	"Cluster 25: Non-specific - Transcription"	"Cluster 21: Lymphoma - Adaptive immune response"	"Cluster 20: Non-specific - Transcription regulation"	68	Nucleoplasm	Vesicles	"CAB010355: , HPA074108: "	"unprognostic (2.24e-2)"	"unprognostic (9.35e-3)"	"unprognostic (4.55e-2)"	"unprognostic (2.57e-2)"	"unprognostic (1.54e-1)"	"unprognostic (3.23e-1)"	"unprognostic (6.23e-3)"	"unprognostic (1.09e-3)"	"unprognostic (1.13e-3)"	"unprognostic (1.43e-2)"	"potential prognostic unfavorable (2.56e-6)"	"unprognostic (2.75e-1)"	"unprognostic (7.81e-2)"	"unprognostic (1.34e-2)"	"unprognostic (1.73e-1)"	"unprognostic (8.01e-2)"	"unprognostic (2.00e-1)"	"unprognostic (2.33e-2)"	"unprognostic (2.53e-3)"	"unprognostic (3.05e-1)"	"unprognostic (5.48e-3)"	"unprognostic (1.33e-1)"	"unprognostic (2.25e-2)"	"unprognostic (1.60e-1)"	"unprognostic (1.80e-1)"	"unprognostic (2.61e-1)"	"potential prognostic favorable (6.20e-6)"	"unprognostic (1.57e-1)"	"unprognostic (2.00e-3)"	"unprognostic (4.50e-2)"	"unprognostic (4.09e-1)"
STAT3	APRF	ENSG00000168610	"Signal transducer and activator of transcription 3"	P40763	17	42313324-42388540	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Host-virus interaction, Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Diabetes mellitus, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enhanced"	"Detected in all"		"Neutrophils: 2979.0"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in all"			"Low lineage specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Colon - Neutrophils"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"HPA001671, CAB003859, HPA058603, CAB068241, CAB068242, CAB080518"	Supported		Enhanced	Nucleoplasm,Cytosol			NA	NA		40000	"Cluster 35: Neutrophils - Protein binding"	"Cluster 45: Liver - Metabolism & Coagulation"	"Cluster 44: Non-specific - Mixed function"	"Cluster 55: Lymphoma - Immune response"	"Cluster 31: Neutrophils - Chemotaxis & Apoptosis"	191	"Nucleoplasm, Cytosol"		"CAB003859: , CAB068241: , CAB068242: , CAB080518: , HPA001671: , HPA058603: "	"unprognostic (2.20e-2)"	"unprognostic (1.39e-1)"	"unprognostic (3.00e-1)"	"unprognostic (1.50e-1)"	"unprognostic (3.62e-2)"	"unprognostic (3.87e-3)"	"unprognostic (6.03e-2)"	"unprognostic (1.08e-2)"	"unprognostic (3.90e-2)"	"unprognostic (8.99e-3)"	"potential prognostic favorable (1.54e-4)"	"unprognostic (2.11e-2)"	"unprognostic (1.91e-1)"	"unprognostic (1.46e-1)"	"unprognostic (6.16e-2)"	"unprognostic (1.66e-1)"	"unprognostic (1.57e-1)"	"unprognostic (5.14e-2)"	"unprognostic (1.86e-2)"	"unprognostic (3.69e-2)"	"unprognostic (2.57e-2)"	"unprognostic (2.12e-1)"	"unprognostic (4.13e-1)"	"unprognostic (2.25e-1)"	"unprognostic (1.36e-1)"	"unprognostic (1.44e-1)"	"unprognostic (1.73e-1)"	"unprognostic (9.39e-3)"	"unprognostic (4.97e-2)"	"unprognostic (1.13e-1)"	"unprognostic (1.03e-1)"
STAT5B		ENSG00000173757	"Signal transducer and activator of transcription 5B"	P51692	17	42199176-42288633	"Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Activator, DNA-binding"	"Cancer-related genes, Disease variant, Dwarfism"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Low tissue specificity"	"Detected in all"			"Cell type enriched"	"Detected in many"	5	"Neutrophils: 1497.8"	"Low cell type specificity"	"Detected in all"			"Low cancer specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"Low immune cell specificity"	"Detected in many"			"Low lineage specificity"	"Detected in many"			"Low cancer specificity"	"Detected in all"			"Pancreas - Endothelial cells, Spleen - Neutrophils_2"	"Low region specificity"	"Detected in all"			"Low region specificity"	"Detected in all"			"CAB004298, CAB005418, HPA042128, HPA049883, HPA051156"	Approved		Supported	Cytosol			NA	NA			"Cluster 35: Neutrophils - Protein binding"	"Cluster 24: Non-specific - Transcription"	"Cluster 56: Hypothalamus - Neuropeptide signaling"	"Cluster 59: Leukemia - T-cell receptor"	"Cluster 24: Neutrophils - Innate immunity signal integration"	28	Cytosol		"CAB004298: , CAB005418: , HPA042128: , HPA049883: , HPA051156: "	"unprognostic (3.74e-3)"	"unprognostic (1.93e-1)"	"unprognostic (6.36e-2)"	"unprognostic (5.10e-2)"	"unprognostic (1.18e-1)"	"unprognostic (6.45e-2)"	"unprognostic (3.43e-1)"	"unprognostic (2.49e-3)"	"unprognostic (3.01e-1)"	"unprognostic (5.33e-2)"	"validated prognostic favorable (1.27e-8)"	"validated prognostic favorable (1.44e-5)"	"unprognostic (1.25e-2)"	"unprognostic (2.04e-1)"	"unprognostic (1.11e-1)"	"unprognostic (1.22e-1)"	"unprognostic (1.25e-1)"	"unprognostic (9.15e-2)"	"unprognostic (1.67e-1)"	"unprognostic (1.11e-2)"	"unprognostic (2.10e-1)"	"potential prognostic favorable (8.97e-4)"	"unprognostic (8.23e-2)"	"unprognostic (2.63e-1)"	"unprognostic (4.71e-3)"	"unprognostic (1.43e-3)"	"unprognostic (2.06e-1)"	"unprognostic (1.97e-1)"	"unprognostic (4.20e-1)"	"unprognostic (2.90e-1)"	"unprognostic (1.68e-1)"
TBX3	"TBX3-ISO, UMS, XHL"	ENSG00000135111	"T-box transcription factor 3"	O15119	12	114670255-114684175	"Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors"	"Transcription, Transcription regulation"	"Developmental protein, DNA-binding, Repressor"	"Cancer-related genes, Disease variant"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"adrenal gland: 171.8"	"Cell type enhanced"	"Detected in many"		"Adrenal cortex cells: 654.2;Basal prostatic cells: 211.0;Breast hormone-responsive cells: 236.9;Prostatic club cells: 337.0;Prostatic glandular cells: 411.3;Prostatic hillock cells: 229.0;Syncytiotrophoblasts: 843.3"	"Group enriched"	"Detected in some"	7	"endothelial cell: 84.1;pericyte: 137.8;vascular associated smooth muscle cell: 48.7"	"Cancer enhanced"	"Detected in all"		"Prostate Adenocarcinoma (TCGA): 87.5"	"Low region specificity"	"Detected in all"			"Not detected in immune cells"	"Not detected"			"Not detected"	"Not detected"			"Cancer enhanced"	"Detected in many"		"Neuroblastoma: 85.1;prostate cancer: 73.8"	"Breast - Breast glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells"	"Low region specificity"	"Detected in single"			"Low region specificity"	"Detected in all"			"HPA005799, HPA075876"			Supported	Nucleoplasm,Cytosol			NA	NA				"Cluster 4: Adrenal gland - Steroid metabolism"	"Cluster 19: Astrocytes - Mixed function"	"Cluster 17: Neuroblastoma - Neuronal signaling"	"Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal"	6	Nucleoplasm	Cytosol	"HPA005799: , HPA075876: "	"potential prognostic favorable (7.57e-5)"	"unprognostic (1.98e-1)"	"unprognostic (2.70e-1)"	"unprognostic (1.23e-1)"	"unprognostic (3.57e-1)"	"unprognostic (2.02e-1)"	"unprognostic (4.71e-2)"	"unprognostic (3.05e-1)"	"unprognostic (2.07e-2)"	"unprognostic (1.97e-2)"	"validated prognostic favorable (6.25e-4)"	"validated prognostic favorable (8.84e-4)"	"unprognostic (6.27e-3)"	"unprognostic (2.31e-1)"	"unprognostic (1.25e-1)"	"unprognostic (1.64e-1)"	"unprognostic (1.12e-1)"	"unprognostic (1.38e-1)"	"unprognostic (6.90e-2)"	"unprognostic (1.25e-1)"	"unprognostic (6.99e-2)"	"unprognostic (2.82e-1)"	"unprognostic (3.65e-2)"	"unprognostic (4.11e-2)"	"unprognostic (3.47e-1)"	"unprognostic (4.31e-3)"	"unprognostic (4.99e-2)"	"unprognostic (2.86e-3)"	"unprognostic (8.94e-2)"	"unprognostic (1.99e-1)"	"unprognostic (4.94e-2)"
TENT5C	"FAM46C, FLJ20202"	ENSG00000183508	"Terminal nucleotidyltransferase 5C"	Q5VWP2	1	117606048-117628389	"Cancer-related genes, Enzymes, Predicted intracellular proteins"	"Host-virus interaction"	"Nucleotidyltransferase, RNA-binding, Transferase"	"Cancer-related genes"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Evidence at protein level"	"Tissue enhanced"	"Detected in many"		"bone marrow: 84.0"	"Cell type enhanced"	"Detected in many"		"Early spermatids: 562.7;Erythrocytes: 315.6;Late spermatids: 2755.6;Plasma cells: 737.7;Platelets: 251.4"	"Group enriched"	"Detected in some"	4	"choroid plexus epithelial cell: 57.5;leukocyte: 94.5"	"Low cancer specificity"	"Detected in many"			"Region enriched"	"Detected in all"	14	"choroid plexus: 57.0"	"Immune cell enhanced"	"Detected in many"		"basophil: 29.5"	"Group enriched"	"Detected in many"	17	"B-cells: 13.4;granulocytes: 29.5;T-cells: 13.7"	"Cancer enriched"	"Detected in many"	8	"Myeloma: 126.2"	"Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids"	"Low region specificity"	"Detected in many"			"Low region specificity"	"Detected in all"			HPA054049	Uncertain		Supported	Nucleoplasm			NA	NA			"Cluster 32: Basophils - Transcription"	"Cluster 21: Testis - Mixed function"	"Cluster 36: Choroid plexus - Mixed function"	"Cluster 51: Myeloma - Immunoglobulins"	"Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization"	2	Nucleoplasm		"HPA054049: "	"unprognostic (2.91e-2)"	"unprognostic (2.20e-1)"		"unprognostic (1.86e-2)"	"unprognostic (4.36e-2)"	"unprognostic (1.76e-1)"		"unprognostic (1.51e-1)"	"unprognostic (1.71e-3)"	"unprognostic (4.35e-2)"	"potential prognostic favorable (6.70e-6)"	"unprognostic (1.96e-2)"	"unprognostic (2.41e-2)"	"unprognostic (1.69e-1)"		"potential prognostic favorable (4.84e-5)"	"unprognostic (2.07e-2)"	"unprognostic (3.05e-2)"	"unprognostic (3.75e-1)"	"unprognostic (1.32e-2)"	"unprognostic (2.16e-1)"	"unprognostic (5.24e-3)"	"unprognostic (1.08e-3)"	"unprognostic (5.68e-2)"	"unprognostic (1.01e-2)"	"unprognostic (2.78e-1)"	"unprognostic (1.12e-1)"	"unprognostic (1.08e-1)"	"unprognostic (3.46e-2)"	"unprognostic (3.63e-2)"	"unprognostic (8.65e-2)"