Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ABCA4 "ABCR, ARMD2, CORD3, FFM, RP19, STGD, STGD1" ENSG00000198691 "ATP binding cassette subfamily A member 4" P78363 1 93992834-94121148 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Age-related macular degeneration, Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 43 "choroid plexus: 93.3;retina: 343.6" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 261.7;Rod photoreceptor cells: 517.5" "Cancer enhanced" "Detected in many" "lung cancer: 3.1" "Region enriched" "Detected in many" 17 "choroid plexus: 313.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA064420, HPA078826" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 36: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "Endoplasmic reticulum" "HPA064420: , HPA078826: " "unprognostic (1.25e-1)" "unprognostic (3.93e-1)" "unprognostic (3.29e-2)" "unprognostic (7.17e-4)" "unprognostic (1.28e-1)" "unprognostic (3.00e-1)" "unprognostic (1.38e-2)" "prognostic favorable (2.45e-4)" "unprognostic (3.77e-2)" "unprognostic (5.25e-1)" "unprognostic (3.70e-1)" "unprognostic (5.18e-2)" "unprognostic (1.17e-9)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (2.47e-1)" "prognostic unfavorable (2.72e-4)" ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Calmodulin-binding, Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 257.7;testis: 99.0" "Group enriched" "Detected in many" 20 "Early spermatids: 373.5;Late spermatids: 1317.0;Proximal enterocytes: 1039.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.2" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Fibroblast_1, Testis - Late spermatids, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" Enzyme NA NA 104000000 170000000 "Cluster 14: Non-specific - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 33: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 549.2;skeletal muscle: 637.1;tongue: 669.0" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 14: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mucus glandular cells: 172.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" Enzyme NA NA 740000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 62: Connective tissue - ECM organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" 4 Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "adrenal gland: 516.2" "Cell type enriched" "Detected in many" 11 "Astrocytes: 2093.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 26.4" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 47: Astrocytes - Unknown function" 1 "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 109.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Supported Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 44: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 1 Mitochondria "HPA004479: AB_1078109, HPA004480: AB_1078108" "unprognostic (1.11e-1)" "unprognostic (7.49e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.31e-1)" "unprognostic (5.06e-3)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (5.35e-2)" "unprognostic (1.54e-2)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "prognostic favorable (6.05e-14)" "unprognostic (5.90e-2)" "unprognostic (9.41e-2)" "unprognostic (5.74e-3)" "unprognostic (2.22e-1)" AGBL5 "CCP5, FLJ21839" ENSG00000084693 "AGBL carboxypeptidase 5" Q8NDL9 2 27042364-27070622 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "parathyroid gland: 48.3;testis: 187.3" "Group enriched" "Detected in many" 6 "Early spermatids: 344.6;Late spermatids: 336.1;Spermatocytes: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030981 Uncertain Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 31: Spermatocytes - Spermatogenesis" "Cytokinetic bridge" "Microtubules, Cytosol" "HPA030981: AB_10611673" "unprognostic (1.29e-2)" "unprognostic (8.70e-2)" "unprognostic (2.26e-1)" "unprognostic (3.13e-3)" "unprognostic (1.95e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.86e-1)" "unprognostic (4.34e-1)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (3.41e-2)" "unprognostic (5.56e-2)" "unprognostic (2.05e-1)" "unprognostic (1.69e-2)" "unprognostic (4.50e-2)" AGK "FLJ10842, MULK" ENSG00000006530 "Acylglycerol kinase" Q53H12 7 141551278-141655244 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Cardiomyopathy, Cataract, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 69.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 97.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020959, HPA053471" Supported Supported Vesicles,Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 30: Heart muscle - Heart development" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 19: NK-cells - Adaptive immune response" 1 Mitochondria Vesicles "HPA020959: AB_1854206, HPA053471: AB_2682164" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.28e-2)" "unprognostic (9.47e-3)" "unprognostic (5.43e-2)" "unprognostic (2.15e-2)" "unprognostic (3.68e-2)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (6.24e-3)" "unprognostic (7.90e-2)" "unprognostic (9.29e-2)" "unprognostic (9.65e-2)" "unprognostic (3.30e-1)" "unprognostic (1.18e-1)" AHR bHLHe76 ENSG00000106546 "Aryl hydrocarbon receptor" P35869 7 16916359-17346152 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Cancer-related genes, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 187.3;Langerhans cells: 269.5;monocytes: 146.6;Schwann cells: 255.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005072, HPA029722, HPA029723" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Liver - Plasma proteins" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 29: Monocytes - Innate immune response" 4 Cytosol Nucleoplasm "CAB005072: AB_633731, HPA029722: AB_10599189, HPA029723: AB_10599025" "unprognostic (1.29e-2)" "unprognostic (1.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.39e-2)" "unprognostic (7.28e-2)" "unprognostic (1.22e-1)" "unprognostic (1.44e-1)" "unprognostic (3.39e-1)" "unprognostic (4.32e-2)" "unprognostic (9.98e-2)" "unprognostic (1.24e-3)" "unprognostic (2.89e-1)" "unprognostic (7.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-2)" "unprognostic (9.45e-2)" AIPL1 LCA4 ENSG00000129221 "Aryl hydrocarbon receptor interacting protein like 1" Q9NZN9 17 6393693-6435199 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 218 "retina: 810.0" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 1366.1;Rod photoreceptor cells: 1629.2" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3;Uterine cancer: 6.6" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA026578 Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 76: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 17 Nucleoplasm "Nuclear speckles, Cytosol" "HPA026578: AB_2671905" "unprognostic (2.42e-2)" "unprognostic (1.17e-1)" "unprognostic (2.02e-2)" "unprognostic (1.68e-3)" "unprognostic (3.24e-1)" "unprognostic (1.13e-3)" "unprognostic (3.76e-1)" "unprognostic (5.35e-2)" ARHGEF18 "KIAA0521, MGC15913, P114-RhoGEF, p114RhoGEF" ENSG00000104880 "Rho/Rac guanine nucleotide exchange factor 18" Q6ZSZ5 19 7348937-7472485 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 74.9;monocytes: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042689, HPA049151, HPA071867" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 73: B-cells - B-cell function" Cytosol "Plasma membrane" "HPA042689: AB_10794385, HPA049151: AB_2680654, HPA071867: AB_2686466" "unprognostic (2.55e-1)" "unprognostic (1.31e-2)" "unprognostic (1.57e-1)" "unprognostic (6.01e-2)" "unprognostic (1.65e-2)" "prognostic favorable (4.21e-4)" "unprognostic (1.13e-1)" "unprognostic (1.52e-3)" "unprognostic (3.56e-1)" "unprognostic (2.36e-1)" "unprognostic (1.40e-1)" "unprognostic (8.26e-2)" "prognostic favorable (3.11e-5)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (1.42e-1)" "unprognostic (3.79e-3)" ARL2BP "BART, BART1, RP66" ENSG00000102931 "ADP ribosylation factor like GTPase 2 binding protein" Q9Y2Y0 16 57245259-57253635 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 546.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043066, HPA048440" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 11: Late spermatids - Unknown function" 7 "Nucleoplasm, Cytosol" "HPA043066: AB_2678302, HPA048440: AB_2680393" "unprognostic (1.17e-1)" "unprognostic (4.05e-2)" "unprognostic (3.32e-2)" "unprognostic (1.74e-1)" "unprognostic (3.33e-3)" "unprognostic (1.26e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (9.06e-5)" "unprognostic (2.38e-1)" "unprognostic (3.06e-1)" "unprognostic (2.07e-1)" "unprognostic (4.10e-2)" "unprognostic (2.71e-3)" "unprognostic (1.44e-1)" "unprognostic (1.58e-1)" "unprognostic (1.47e-2)" "unprognostic (6.78e-2)" ARL3 ARFL3 ENSG00000138175 "ADP ribosylation factor like GTPase 3" P36405 10 102673731-102714397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 93.4" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 343.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036292, HPA063596" Approved Supported Nucleoplasm,Centrosome NA NA 44000 "Cluster 4: Neutrophils - Degranulation" "Cluster 76: Retina - Visual perception" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 66: Photoreceptor cells - Visual perception" 11 Centrosome Nucleoplasm "HPA036292: AB_10673618, HPA063596: AB_2685053" "unprognostic (1.36e-1)" "unprognostic (2.89e-3)" "unprognostic (4.19e-2)" "unprognostic (7.58e-2)" "unprognostic (2.98e-2)" "unprognostic (3.24e-2)" "unprognostic (2.45e-2)" "unprognostic (7.69e-2)" "unprognostic (4.00e-2)" "unprognostic (3.21e-1)" "unprognostic (3.99e-3)" "unprognostic (5.58e-2)" "prognostic favorable (1.71e-6)" "unprognostic (5.62e-2)" "unprognostic (3.09e-2)" "unprognostic (4.21e-2)" "unprognostic (1.03e-1)" ARL6 "BBS3, RP55" ENSG00000113966 "ADP ribosylation factor like GTPase 6" Q9H0F7 3 97764521-97801229 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 36.8" "Cell type enhanced" "Detected in many" "Early spermatids: 33.7;Excitatory neurons: 53.2;Inhibitory neurons: 49.4;Rod photoreceptor cells: 54.6;Spermatocytes: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019361 Approved Supported Microtubules NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 4 Microtubules "HPA019361: AB_1845028" "unprognostic (1.31e-1)" "unprognostic (2.82e-2)" "unprognostic (7.12e-2)" "unprognostic (4.66e-2)" "unprognostic (2.08e-1)" "unprognostic (1.02e-1)" "unprognostic (8.78e-3)" "unprognostic (2.88e-2)" "unprognostic (5.55e-3)" "unprognostic (9.43e-2)" "unprognostic (1.19e-1)" "unprognostic (3.31e-1)" "prognostic favorable (2.53e-7)" "unprognostic (9.49e-2)" "unprognostic (1.67e-1)" "unprognostic (2.16e-2)" "unprognostic (2.97e-1)" ARMS2 "ARMD8, LOC387715" ENSG00000254636 "Age-related maculopathy susceptibility 2" P0C7Q2 10 122454653-122457352 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.3;testis: 2.8" "Cell type enriched" "Detected in some" 6 "Late spermatids: 63.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" HPA067225 Enhanced NA NA "Cluster 21: Testis - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 63: Late spermatids - Spermatogenesis" 2 "HPA067225: AB_2685806" "unprognostic (3.05e-1)" "unprognostic (1.50e-1)" "unprognostic (5.69e-3)" "unprognostic (2.29e-1)" "unprognostic (2.61e-2)" "unprognostic (2.84e-2)" "unprognostic (3.49e-2)" "unprognostic (1.98e-2)" "unprognostic (3.47e-3)" "unprognostic (3.60e-2)" "unprognostic (5.29e-5)" "unprognostic (2.53e-2)" "unprognostic (9.46e-3)" "unprognostic (2.68e-2)" "unprognostic (5.25e-2)" ARR3 ARRX ENSG00000120500 "Arrestin 3" P36575 X 70268305-70281840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 183 "retina: 373.6" "Cell type enriched" "Detected in some" 28 "Cone photoreceptor cells: 4930.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA063129 Enhanced Approved "Golgi apparatus" NA NA "Cluster 76: Retina - Visual perception" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 6 "Golgi apparatus" "HPA063129: AB_2732696" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.70e-2)" "unprognostic (5.37e-2)" "unprognostic (2.82e-1)" "unprognostic (1.37e-2)" "unprognostic (2.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.33e-1)" "unprognostic (4.02e-3)" "unprognostic (2.77e-7)" "unprognostic (8.64e-2)" "unprognostic (6.53e-2)" "unprognostic (6.06e-2)" "unprognostic (1.43e-1)" ARSG KIAA1001 ENSG00000141337 "Arylsulfatase G" Q96EG1 17 68259182-68422731 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Hydrolase "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 29.5" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023245, HPA023285" Enhanced "Intracellular and membrane" Enzyme NA NA 4400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 55: Non-specific - Transcription" "HPA023245: AB_1845056, HPA023285: AB_1845057" "unprognostic (3.66e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" "unprognostic (1.61e-1)" "unprognostic (9.02e-2)" "unprognostic (3.67e-3)" "unprognostic (4.11e-1)" "unprognostic (1.14e-3)" "unprognostic (5.18e-2)" "unprognostic (5.47e-2)" "unprognostic (6.11e-7)" "unprognostic (4.24e-3)" "prognostic favorable (7.04e-4)" "unprognostic (1.87e-2)" "unprognostic (3.68e-2)" "unprognostic (3.18e-2)" "unprognostic (1.49e-1)" ASB10 GLC1F ENSG00000146926 "Ankyrin repeat and SOCS box containing 10" Q8WXI3 7 151175698-151187832 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 25.9;skeletal muscle: 75.2;tongue: 13.6" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 39.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA079685 Enhanced NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 35: RS4;11 - Unknown function" "Cluster 2: Skeletal myocytes - Muscle contraction" 1 "HPA079685: " "unprognostic (6.72e-3)" "unprognostic (1.96e-1)" ATF6 ATF6A ENSG00000118217 "Activating transcription factor 6" P18850 1 161766298-161977574 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005935 Approved NA NA 46000000 "Cluster 28: Neutrophils - Unknown function" "Cluster 68: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Monocytes - Innate immune response" 2 "HPA005935: AB_2667472" "unprognostic (1.31e-1)" "unprognostic (5.15e-3)" "unprognostic (3.18e-2)" "unprognostic (8.43e-3)" "unprognostic (1.59e-1)" "unprognostic (5.58e-3)" "unprognostic (1.24e-1)" "unprognostic (5.32e-2)" "unprognostic (3.37e-2)" "unprognostic (3.24e-1)" "unprognostic (6.09e-3)" "unprognostic (3.38e-1)" "unprognostic (7.55e-2)" "unprognostic (2.03e-1)" "unprognostic (2.43e-1)" "unprognostic (1.56e-2)" "unprognostic (7.57e-3)" ATOH7 "bHLHa13, Math5" ENSG00000179774 "Atonal bHLH transcription factor 7" Q8N100 10 68230595-68232113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.1;kidney: 1.1;liver: 3.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.6;Spermatogonia: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.0" "Kidney - Proximal tubular cells" "Region enriched" "Detected in some" 9 "cerebellum: 28.7" "Low region specificity" "Detected in some" HPA027008 Uncertain NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Neurons - Neuronal signaling" "HPA027008: AB_10600783" "unprognostic (7.17e-2)" "unprognostic (2.81e-1)" "unprognostic (7.66e-2)" "unprognostic (1.86e-2)" "unprognostic (2.20e-3)" "unprognostic (7.40e-2)" "unprognostic (7.76e-2)" "unprognostic (6.16e-2)" "unprognostic (2.46e-1)" "unprognostic (9.28e-4)" "unprognostic (4.96e-3)" "unprognostic (1.17e-1)" "unprognostic (5.06e-4)" "unprognostic (1.72e-1)" "unprognostic (2.52e-2)" "unprognostic (1.36e-1)" "unprognostic (7.18e-2)" BBS2 BBS ENSG00000125124 "Bardet-Biedl syndrome 2" Q9BXC9 16 56465640-56582667 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 136.9;Oligodendrocytes: 91.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040961, HPA041315, HPA059900" Approved Approved Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 33: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 47: Astrocytes - Unknown function" 19 Vesicles "HPA040961: , HPA041315: AB_10960892, HPA059900: " "unprognostic (1.43e-1)" "unprognostic (3.13e-3)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (7.58e-2)" "unprognostic (1.51e-2)" "unprognostic (4.22e-2)" "unprognostic (2.79e-2)" "unprognostic (2.11e-1)" "unprognostic (3.29e-2)" "unprognostic (3.76e-3)" "unprognostic (2.68e-1)" "prognostic favorable (2.83e-6)" "unprognostic (2.16e-1)" "unprognostic (1.61e-1)" "unprognostic (2.95e-1)" "unprognostic (2.95e-2)" BEST1 "BEST, BMD, RP50, VMD2" ENSG00000167995 "Bestrophin 1" O76090 11 61950063-61965515 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.0;brain: 32.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.3;Kupffer cells: 32.2;monocytes: 51.4;Oligodendrocytes: 40.1" "Group enriched" "Detected in some" 6 "glioma: 2.0;melanoma: 6.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 37.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 37.8" "Cancer enriched" "Detected in many" 4 "skin cancer: 18.3" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057464 Enhanced NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 74: Neutrophils - Degranulation" "HPA057464: AB_2683444" "unprognostic (2.41e-3)" "unprognostic (3.67e-2)" "unprognostic (5.91e-3)" "unprognostic (1.21e-1)" "unprognostic (1.25e-1)" "unprognostic (2.73e-1)" "unprognostic (1.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.07e-3)" "unprognostic (2.06e-1)" "unprognostic (4.27e-10)" "unprognostic (1.38e-1)" "unprognostic (4.93e-2)" "unprognostic (3.59e-3)" "unprognostic (2.72e-3)" BFSP1 "CP115, CP94, filensin, LIFL-H" ENSG00000125864 "Beaded filament structural protein 1" Q12934 20 17493905-17569220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 6.1;NK-cells: 9.9;Spermatogonia: 14.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.5" "Lineage enhanced" "Detected in single" "T-cells: 2.5" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "amygdala: 3.2;cerebral cortex: 4.0;hippocampal formation: 4.5" "HPA040748, HPA042038" Enhanced Supported "Plasma membrane,Cytosol" No No "Cluster 1: T-cells - Unknown function" "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 67: Spermatogonia - Spermatogenesis" 1 "Plasma membrane, Cytosol" "HPA040748: AB_10963786, HPA042038: AB_10964054" "unprognostic (2.24e-3)" "unprognostic (1.99e-1)" "unprognostic (1.63e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.07e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-6)" "unprognostic (5.11e-2)" "unprognostic (5.53e-1)" "unprognostic (2.10e-4)" "unprognostic (1.75e-1)" "unprognostic (8.81e-2)" "unprognostic (3.35e-4)" "unprognostic (4.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.78e-2)" "unprognostic (7.50e-2)" BFSP2 "CP47, CP49, LIFL-L, phakinin" ENSG00000170819 "Beaded filament structural protein 2" Q13515 3 133400056-133475222 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 4 "Plasma cells: 16.3" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 8 "T-reg: 13.4" "Lineage enriched" "Detected in single" 43 "T-cells: 13.4" "Cancer enhanced" "Detected in single" "lymphoma: 1.2" "Kidney - Intercalated cells, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038464, HPA062959" Enhanced Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" 44 "Plasma membrane, Cytosol" "HPA038464: AB_10672746, HPA062959: AB_2684912" "unprognostic (1.58e-3)" "unprognostic (7.47e-4)" "unprognostic (1.04e-2)" "unprognostic (2.32e-1)" "unprognostic (9.59e-2)" "unprognostic (4.04e-5)" "unprognostic (8.13e-2)" "unprognostic (5.57e-2)" "unprognostic (6.71e-2)" "unprognostic (1.91e-3)" "unprognostic (1.74e-2)" "unprognostic (4.70e-2)" "unprognostic (1.68e-5)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "unprognostic (8.23e-2)" "unprognostic (2.21e-2)" C1QTNF5 "CTRP5, DKFZp586B0621, LORD" ENSG00000223953 "C1q and TNF related 5" Q9BXJ0 11 119338942-119340940 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "choroid plexus: 571.0" "Cell type enhanced" "Detected in some" "Endothelial cells: 1.4;Fibroblasts: 2.9;Gastric mucus-secreting cells: 1.8;Smooth muscle cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 6.7;Sarcoma: 4.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025607, HPA038604" Uncertain "Secreted to blood" "Complement pathway" NA NA 219000000 1500000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 49: Non-specific - Transcription" 5 "CAB025607: , HPA038604: AB_2676110" C2 ENSG00000166278 "Complement C2" P06681 6 31897785-31945673 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 466.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 194.1;Hepatocytes: 323.8;Hofbauer cells: 241.9;Kupffer cells: 141.5" "Cancer enriched" "Detected in all" 9 "liver cancer: 100.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.7;non-classical monocyte: 26.1" "Lineage enriched" "Detected in single" 33 "monocytes: 26.1" "Group enriched" "Detected in many" 4 "liver cancer: 11.4;Myeloma: 14.9;thyroid cancer: 5.1" "Adipose subcutaneous - Macrophages, Liver - Hepatocytes, Skin - Fibroblast_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB016775 Supported "Secreted to blood" "Complement pathway" NA NA 34000000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 62: Hepatocytes - Metabolism" 6 "CAB016775: " "unprognostic (2.05e-1)" "unprognostic (1.22e-1)" "unprognostic (7.68e-2)" "unprognostic (1.49e-3)" "unprognostic (7.40e-2)" "unprognostic (3.34e-2)" "unprognostic (1.36e-2)" "unprognostic (8.88e-3)" "unprognostic (3.02e-1)" "unprognostic (2.59e-3)" "unprognostic (3.27e-2)" "unprognostic (3.15e-3)" "prognostic unfavorable (2.64e-7)" "unprognostic (2.05e-1)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.55e-2)" C3 "ARMD9, C3a, C3b, CPAMD1" ENSG00000125730 "Complement C3" P01024 19 6677704-6730562 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Fatty acid metabolism, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Age-related macular degeneration, Disease variant, FDA approved drug targets, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "liver: 5250.9" "Cell type enhanced" "Detected in many" "Ductal cells: 657.6;Exocrine glandular cells: 845.2;Hepatocytes: 3158.4;Mesothelial cells: 2220.5" "Cancer enriched" "Detected in all" 5 "liver cancer: 1213.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "non-classical monocyte: 14.5" "Lineage enriched" "Detected in many" 5 "monocytes: 14.5" "Cancer enhanced" "Detected in many" "liver cancer: 255.0" "Liver - Hepatocytes, Lung - Fibroblast_2, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003563, CAB004209, HPA020432" Enhanced "Secreted to blood" "Complement pathway" NA NA 1260000000000 200000000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 83: Liver - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Hepatocytes - Metabolism" 9 "CAB004209: AB_627277, HPA003563: AB_1847117, HPA020432: AB_1847118" "unprognostic (3.26e-3)" "unprognostic (3.91e-1)" "unprognostic (3.92e-1)" "unprognostic (5.98e-3)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "prognostic favorable (8.11e-4)" "unprognostic (1.99e-1)" "unprognostic (9.26e-2)" "unprognostic (5.80e-2)" "unprognostic (8.12e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.63e-2)" "unprognostic (2.49e-2)" "unprognostic (6.03e-3)" "unprognostic (3.88e-1)" C9 ENSG00000113600 "Complement C9" P02748 5 39284140-39371324 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Complement pathway, Cytolysis, Immunity, Innate immunity" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 264 "liver: 1268.7" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 1939.7" "Cancer enriched" "Detected in single" 244 "liver cancer: 90.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002151, HPA029577" Uncertain "Secreted to blood" "Complement pathway" NA NA 69600000000 64000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 59: Leukemia - T-cell receptor" "Cluster 62: Hepatocytes - Metabolism" 2 "CAB002151: AB_563670, HPA029577: AB_10603779" "unprognostic (1.00e-1)" "unprognostic (1.57e-1)" "unprognostic (1.50e-1)" "unprognostic (2.01e-1)" "unprognostic (6.58e-2)" "unprognostic (1.30e-1)" "unprognostic (2.91e-1)" "unprognostic (5.49e-3)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (2.19e-2)" "unprognostic (9.43e-5)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "unprognostic (2.04e-1)" CA4 "CAIV, Car4, RP17" ENSG00000167434 "Carbonic anhydrase 4" P22748 17 60149942-60170899 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 254.9" "Cell type enriched" "Detected in many" 5 "Paneth cells: 4309.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.3" "Region enriched" "Detected in all" 5 "cerebellum: 173.8" "Immune cell enriched" "Detected in some" 7 "neutrophil: 100.0" "Lineage enriched" "Detected in single" 1000 "granulocytes: 100.0" "Cancer enhanced" "Detected in some" "Brain cancer: 4.3;liver cancer: 7.8;prostate cancer: 7.4" "Adipose visceral - Endothelial cells, Colon - Colon enterocytes" "Region enriched" "Detected in all" 5 "cerebellum: 300.3" "Low region specificity" "Detected in all" "HPA011089, HPA017258" Enhanced Uncertain Vesicles,Cytosol NA NA 190000 "Cluster 21: Neutrophils - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 5: Enterocytes - Absorption" 1 Cytosol Vesicles "HPA011089: AB_1845996, HPA017258: AB_1845997" "unprognostic (2.07e-2)" "unprognostic (7.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.78e-3)" "unprognostic (8.42e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (5.84e-2)" "unprognostic (7.76e-2)" "unprognostic (9.74e-2)" "unprognostic (1.54e-1)" "unprognostic (1.71e-2)" "unprognostic (2.68e-3)" "unprognostic (8.59e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-2)" CACNA1F "AIED, Cav1.4, CORDX3, CSNB2, CSNB2A, CSNBX2, JM8, JMC8, OA2" ENSG00000102001 "Calcium voltage-gated channel subunit alpha1 F" O60840 X 49205063-49233371 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Sensory transduction, Transport, Vision" "Calcium channel, Ion channel, Voltage-gated channel" "Cone-rod dystrophy, Congenital stationary night blindness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 63 "retina: 121.4" "Group enriched" "Detected in some" 7 "Bipolar cells: 66.4;Cone photoreceptor cells: 73.1;Rod photoreceptor cells: 91.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA068379 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA068379: AB_2732782" "unprognostic (1.20e-3)" "unprognostic (8.62e-2)" "unprognostic (4.25e-3)" "unprognostic (1.56e-2)" "unprognostic (8.46e-2)" "unprognostic (1.84e-1)" "unprognostic (1.23e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (9.04e-2)" "unprognostic (7.36e-2)" "unprognostic (1.59e-1)" "unprognostic (6.08e-7)" "unprognostic (8.03e-2)" "unprognostic (1.09e-1)" "unprognostic (4.65e-2)" "unprognostic (3.77e-3)" CACNA2D4 alpha2delta-4 ENSG00000151062 "Calcium voltage-gated channel auxiliary subunit alpha2delta 4" Q7Z3S7 12 1791963-1918666 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 40 "retina: 19.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.1;Cone photoreceptor cells: 79.9;Hofbauer cells: 32.6;Late spermatids: 125.0;Rod photoreceptor cells: 97.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 2.9;monocytes: 4.4;T-cells: 4.2" "Group enriched" "Detected in some" 4 "Leukemia: 7.5;lymphoma: 3.1;Sarcoma: 2.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA031952 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Retina - Visual perception" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 11: Late spermatids - Unknown function" "HPA031952: AB_10600798" "unprognostic (5.04e-2)" "unprognostic (2.82e-2)" "unprognostic (5.32e-1)" "unprognostic (7.50e-2)" "unprognostic (1.15e-1)" "unprognostic (8.18e-4)" "unprognostic (1.10e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-1)" "unprognostic (3.30e-3)" "unprognostic (1.24e-2)" "unprognostic (1.41e-1)" "unprognostic (1.62e-5)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.04e-1)" "unprognostic (2.13e-1)" CAPN5 "ADNIV, HTRA3, nCL-3, VRNI" ENSG00000149260 "Calpain 5" O15484 11 77066961-77126155 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 59.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 140.1;Gastric mucus-secreting cells: 71.9;Intestinal goblet cells: 104.6;Paneth cells: 68.4;Proximal enterocytes: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Lineage enriched" "Detected in single" 4 "T-cells: 1.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Stomach - Gastric mucous cells, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033237, HPA072319" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" Nucleoplasm Cytosol "CAB033237: AB_2069673, HPA072319: AB_2686512" "unprognostic (6.81e-3)" "unprognostic (1.31e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (3.47e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (5.30e-2)" "unprognostic (2.52e-1)" "unprognostic (2.21e-2)" "unprognostic (5.35e-3)" "unprognostic (4.64e-1)" "unprognostic (3.17e-3)" "unprognostic (8.58e-3)" "unprognostic (3.25e-1)" "unprognostic (2.31e-2)" "unprognostic (2.30e-3)" CDH23 "CDHR23, DFNB12, USH1D" ENSG00000107736 "Cadherin related 23" Q9H251 10 71396920-71815947 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 34.2" "Cell type enhanced" "Detected in many" "Early spermatids: 52.7;Late spermatids: 82.5;Microglial cells: 32.2;monocytes: 75.0;Muller glia cells: 81.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 26.8;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 4 "monocytes: 38.2" "Cancer enhanced" "Detected in many" "Bone cancer: 9.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA017232 Approved NA NA 950000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Neuronal - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 10: Muller glia cells - Visual perception" "HPA017232: AB_1845903" "unprognostic (6.76e-2)" "unprognostic (2.86e-3)" "unprognostic (3.82e-2)" "unprognostic (3.13e-3)" "unprognostic (1.07e-1)" "unprognostic (5.52e-2)" "unprognostic (7.93e-2)" "unprognostic (2.88e-1)" "unprognostic (6.44e-3)" "unprognostic (4.67e-2)" "unprognostic (2.05e-1)" "unprognostic (9.23e-3)" "unprognostic (2.14e-3)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "prognostic favorable (3.40e-4)" CDHR1 "CORD15, KIAA1775, PCDH21, RP65" ENSG00000148600 "Cadherin related family member 1" Q96JP9 10 84194537-84219621 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 304.3;skin 1: 208.5" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 360.2;Rod photoreceptor cells: 214.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 13.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "NK-cell: 7.5" "Lineage enriched" "Detected in single" 12 "NK-cells: 7.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.9" "Adipose visceral - T-cells, Colon - Colon enterocytes, Liver - NK-cells (Liver), Skin - Keratinocyte (other), Stomach - Fibroblasts, Thyroid - T-cells" "Region enriched" "Detected in many" 21 "olfactory bulb: 333.1" "Low region specificity" "Detected in all" "HPA010795, HPA036819" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Receptor NA NA 55000 "Cluster 15: NK-cells - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "Golgi apparatus" "HPA010795: , HPA036819: AB_10671750" "unprognostic (8.91e-4)" "unprognostic (5.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.71e-2)" "unprognostic (2.63e-2)" "unprognostic (3.03e-2)" "unprognostic (6.40e-2)" "unprognostic (7.77e-2)" "unprognostic (1.41e-1)" "unprognostic (2.67e-1)" "unprognostic (6.69e-4)" "unprognostic (1.90e-1)" "unprognostic (5.51e-3)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (4.56e-3)" "unprognostic (5.07e-2)" CEP250 "C-NAP1, CEP2" ENSG00000126001 "Centrosomal protein 250" Q9BV73 20 35455164-35519280 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation" "Cone-rod dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064875 Supported Centrosome NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 78: Testis - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 49: Non-specific - Transcription" 2 Centrosome "HPA064875: AB_2685379" "unprognostic (6.35e-2)" "unprognostic (2.94e-1)" "unprognostic (2.31e-1)" "unprognostic (1.21e-3)" "unprognostic (1.99e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (1.77e-7)" "unprognostic (1.60e-1)" "unprognostic (7.81e-2)" "unprognostic (3.47e-2)" "prognostic favorable (9.27e-6)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.97e-6)" "unprognostic (1.30e-1)" "unprognostic (6.40e-2)" "unprognostic (2.90e-3)" "unprognostic (4.57e-2)" CEP290 "3H11Ag, BBS14, CT87, FLJ13615, JBTS5, KIAA0373, LCA10, MKS4, NPHP6, POC3, rd16, SLSN6" ENSG00000198707 "Centrosomal protein 290" O15078 12 88049016-88142099 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" Activator "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Leber congenital amaurosis, Meckel syndrome, Nephronophthisis, Obesity, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 214.3;Spermatocytes: 158.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB029995, HPA043918, HPA064397" Approved Supported Centrosome NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Neuronal - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 38: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium assembly" 9 Centrosome "CAB029995: , HPA043918: AB_2678730, HPA064397: AB_2685255" "unprognostic (7.42e-2)" "unprognostic (4.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "unprognostic (3.26e-1)" "unprognostic (8.90e-2)" "unprognostic (1.45e-4)" "unprognostic (2.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (2.94e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (3.21e-6)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (2.44e-2)" "unprognostic (3.84e-3)" CEP78 "C9orf81, FLJ12643" ENSG00000148019 "Centrosomal protein 78" Q5JTW2 9 78236062-78279690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Cone-rod dystrophy, Deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 69.7;NK-cells: 213.1;Spermatocytes: 79.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 39.2" "Group enriched" "Detected in many" 5 "NK-cells: 39.2;T-cells: 18.4" "Low cancer specificity" "Detected in all" "Lung - NK-cells (Lung), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048846 Approved NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 19: NK-cells - Adaptive immune response" "HPA048846: AB_2680537" "unprognostic (4.62e-1)" "unprognostic (6.33e-3)" "unprognostic (2.87e-2)" "unprognostic (1.36e-2)" "unprognostic (2.16e-1)" "unprognostic (1.36e-2)" "unprognostic (5.13e-4)" "unprognostic (6.75e-2)" "unprognostic (8.48e-3)" "unprognostic (2.10e-1)" "unprognostic (1.38e-2)" "unprognostic (7.03e-2)" "unprognostic (1.25e-2)" "unprognostic (2.27e-3)" "unprognostic (4.93e-1)" "unprognostic (1.18e-3)" "unprognostic (3.34e-1)" CERKL RP26 ENSG00000188452 "Ceramide kinase like" Q49MI3 2 181535041-181680665 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.7;retina: 20.4" "Cell type enhanced" "Detected in some" "Ciliated cells: 34.3;Cone photoreceptor cells: 18.7;Oocytes: 14.7;Proximal tubular cells: 9.3;Rod photoreceptor cells: 26.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 28.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 5.2" "Adipose visceral - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 18.5" "HPA035443, HPA035444, HPA043203" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Neuronal - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" "Nucleoplasm, Cytosol" "HPA035443: AB_2674625, HPA035444: AB_10672093, HPA043203: " "unprognostic (7.52e-3)" "unprognostic (6.13e-3)" "unprognostic (2.09e-1)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (2.71e-3)" "unprognostic (2.59e-1)" "unprognostic (1.39e-2)" "unprognostic (2.76e-1)" "unprognostic (2.27e-1)" "prognostic favorable (5.25e-4)" "unprognostic (4.54e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.37e-1)" "unprognostic (3.65e-2)" "unprognostic (3.07e-2)" "unprognostic (8.45e-2)" CFAP418 "BBS21, C8orf37, CORD16, FAP418, FLJ30600, MOT25, RP64" ENSG00000156172 "Cilia and flagella associated protein 418" Q96NL8 8 95244913-95269201 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Cone-rod dystrophy, Disease variant, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 10.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024198 Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 40: Prostatic glandular cells - Transcription" 3 Cytosol "Plasma membrane, Cell Junctions" "HPA024198: AB_1845775" "unprognostic (7.90e-2)" "unprognostic (1.98e-2)" "unprognostic (5.68e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (2.72e-3)" "unprognostic (4.20e-3)" "unprognostic (2.04e-2)" "unprognostic (8.94e-2)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (6.11e-3)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (6.72e-3)" "unprognostic (2.02e-1)" "unprognostic (1.33e-2)" "unprognostic (3.29e-1)" CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952086 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 2453.1" "Cell type enhanced" "Detected in many" "Ductal cells: 913.7;Exocrine glandular cells: 569.1;Hepatocytes: 199.3;Mesothelial cells: 453.1;Pancreatic endocrine cells: 368.5" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 34.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Mesothelial cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" Immunity NA NA 879000000 120000000000 "Cluster 83: Liver - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196651754-196752476 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1645.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 355.9;Hepatocytes: 834.8;Leydig cells: 285.2;Mesothelial cells: 388.2;Ovarian stromal cells: 208.2" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Region enhanced" "Detected in all" "choroid plexus: 43.6" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 17.6" "Lineage enriched" "Detected in single" 56 "T-cells: 17.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 59.2" "Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Fibroblast_2" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" Immunity NA NA 396000000000 100000000000 "Cluster 1: T-cells - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 53: Fibroblasts - ECM organization" 6 Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196837159 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 224 "liver: 2010.5" "Cell type enhanced" "Detected in some" "Granulosa cells: 65.7;Hepatocytes: 223.4;Kupffer cells: 55.4" "Cancer enriched" "Detected in single" 798 "liver cancer: 182.4" "Region enhanced" "Detected in single" "midbrain: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.3;thyroid cancer: 7.0" "Liver - Hepatocytes" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" "Complement pathway" NA NA 13000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 62: Hepatocytes - Metabolism" 6 Vesicles "HPA038915: AB_2676269, HPA038922: AB_2676271, HPA040726: AB_2677101" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.88e-2)" "prognostic favorable (8.71e-6)" "unprognostic (3.02e-1)" "unprognostic (3.70e-1)" "unprognostic (2.50e-1)" "unprognostic (8.48e-2)" "unprognostic (7.21e-4)" "unprognostic (7.01e-4)" "unprognostic (1.13e-1)" "unprognostic (6.41e-2)" CFI "C3b-INA, FI, IF, KAF" ENSG00000205403 "Complement factor I" P05156 4 109731008-109802150 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 952.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 108.7;Hepatocytes: 454.5;Muller glia cells: 114.1;Proximal tubular cells: 195.1" "Cancer enhanced" "Detected in all" "liver cancer: 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Colon - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001143, CAB016777, HPA024061" Supported "Secreted to blood" "Complement pathway" NA NA 12000000000 "Cluster 1: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 62: Hepatocytes - Metabolism" 1 "CAB016777: , HPA001143: AB_1078555, HPA024061: AB_1847129" "unprognostic (1.04e-1)" "unprognostic (5.79e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (1.55e-2)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (2.00e-2)" "unprognostic (5.42e-3)" "unprognostic (1.41e-1)" "unprognostic (3.61e-1)" "unprognostic (8.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.06e-4)" CHM "DXS540, REP-1, TCD" ENSG00000188419 "CHM Rab escort protein" P24386 X 85861180-86047561 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003231, CAB016171" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 51: Thyroid gland - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 69: Neurons - Neuronal signaling" 1 Nucleoplasm Cytosol "CAB016171: AB_2229397, HPA003231: AB_1078518" "unprognostic (6.50e-3)" "unprognostic (1.80e-1)" "unprognostic (1.67e-1)" "unprognostic (1.74e-2)" "unprognostic (2.82e-1)" "unprognostic (4.40e-1)" "unprognostic (6.20e-3)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-1)" "unprognostic (2.20e-1)" "unprognostic (1.49e-1)" "unprognostic (1.97e-3)" "unprognostic (4.18e-2)" "unprognostic (6.15e-2)" "unprognostic (2.44e-1)" "unprognostic (7.60e-3)" CHMP4B "C20orf178, dJ553F4.4, Shax1, SNF7-2, VPS32B" ENSG00000101421 "Charged multivesicular body protein 4B" Q9H444 20 33811348-33854366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 489.3;Syncytiotrophoblasts: 470.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041401, HPA051751" Enhanced NA NA 53000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 54: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 45: Non-specific - Mixed function" 14 "HPA041401: AB_10965028, HPA051751: AB_2681591" "unprognostic (2.56e-2)" "unprognostic (6.12e-2)" "unprognostic (1.07e-1)" "unprognostic (9.04e-3)" "unprognostic (9.85e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.49e-1)" "unprognostic (4.37e-2)" "unprognostic (1.24e-2)" "unprognostic (6.44e-3)" "unprognostic (1.31e-1)" "unprognostic (6.09e-2)" "unprognostic (2.31e-1)" "unprognostic (5.50e-2)" "unprognostic (1.20e-2)" "unprognostic (3.33e-2)" CHN1 "ARHGAP2, CHN, DURS2, n-chimerin, RhoGAP2" ENSG00000128656 "Chimerin 1" P15882 2 174798809-175005381 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "brain: 860.2" "Cell type enhanced" "Detected in many" "Astrocytes: 185.2;Excitatory neurons: 576.4;Horizontal cells: 95.0;Inhibitory neurons: 107.0;Microglial cells: 93.0;Oligodendrocyte precursor cells: 140.6" "Cancer enhanced" "Detected in all" "glioma: 18.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 6.8;memory CD8 T-cell: 2.2;T-reg: 8.5" "Lineage enriched" "Detected in single" 19 "T-cells: 8.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Prostate - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036111 Approved Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" 4 Cytosol "HPA036111: AB_10671241" "unprognostic (3.18e-3)" "unprognostic (4.19e-2)" "unprognostic (9.69e-2)" "unprognostic (3.42e-3)" "unprognostic (1.92e-1)" "unprognostic (2.65e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "unprognostic (3.71e-2)" "unprognostic (1.34e-2)" "unprognostic (5.29e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (7.31e-3)" "unprognostic (4.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.46e-2)" CHRDL1 "CHL, MGC1, NRLN1" ENSG00000101938 "Chordin like 1" Q9BU40 X 110673856-110795819 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Neurogenesis, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 216.7" "Cell type enhanced" "Detected in many" "Astrocytes: 47.7;Fibroblasts: 82.7;Leydig cells: 38.5;Lymphatic endothelial cells: 152.5;Mesothelial cells: 48.5;Muller glia cells: 64.5" "Cancer enhanced" "Detected in many" "prostate cancer: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 59.3" "Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000226, HPA000250" Approved "Secreted in other tissues" "Developmental protein" NA NA 610000 "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "HPA000226: AB_1078522, HPA000250: AB_1078521" "unprognostic (5.13e-2)" "unprognostic (6.31e-2)" "unprognostic (8.50e-3)" "unprognostic (2.48e-3)" "unprognostic (1.99e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.42e-2)" "unprognostic (4.89e-2)" "unprognostic (5.54e-2)" "unprognostic (3.43e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (2.36e-4)" "unprognostic (4.75e-3)" "unprognostic (7.91e-2)" "unprognostic (5.01e-2)" "prognostic unfavorable (2.23e-4)" CHST6 MCDC1 ENSG00000183196 "Carbohydrate sulfotransferase 6" Q9GZX3 16 75472052-75495445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.2;brain: 9.1;cervix: 9.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 14.2;Ciliated cells: 65.1;Club cells: 12.5;Ionocytes: 39.0;Oligodendrocytes: 15.8;Serous glandular cells: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 6.8" "Lung - Respiratory ciliated cells" HPA068029 Approved "Intracellular and membrane" Enzyme NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 42: Ciliated cells - Cilium assembly" "HPA068029: " "unprognostic (2.28e-2)" "unprognostic (2.25e-2)" "unprognostic (1.07e-1)" "unprognostic (3.93e-3)" "unprognostic (3.30e-2)" "unprognostic (4.02e-2)" "unprognostic (7.15e-2)" "unprognostic (1.73e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (3.16e-2)" "unprognostic (1.07e-1)" "unprognostic (1.10e-7)" "unprognostic (1.23e-1)" "unprognostic (1.14e-1)" "unprognostic (5.78e-2)" "unprognostic (2.80e-4)" CIB2 "DFNB48, KIP2, USH1J" ENSG00000136425 "Calcium and integrin binding family member 2" O75838 15 78104606-78131535 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 46.2;lymphoid tissue: 46.7" "Cell type enriched" "Detected in many" 4 "Late spermatids: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in single" 48 "dendritic cells: 18.7" "Cancer enhanced" "Detected in all" "testis cancer: 45.5" "Liver - Vascular Endothelial cells, Stomach - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036697 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 11: Neuronal - Sensory perception" "Cluster 36: Late spermatids - Unknown function" "HPA036697: AB_10672475" "unprognostic (5.77e-2)" "unprognostic (1.83e-2)" "unprognostic (2.81e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.46e-1)" "unprognostic (2.57e-1)" "unprognostic (1.11e-2)" "unprognostic (6.73e-3)" "unprognostic (1.66e-1)" "unprognostic (9.94e-3)" "unprognostic (3.18e-1)" "unprognostic (7.49e-2)" "prognostic favorable (6.16e-4)" "unprognostic (9.78e-2)" "unprognostic (1.01e-1)" "unprognostic (1.68e-1)" "unprognostic (7.64e-3)" CLCC1 MCLC ENSG00000121940 "Chloride channel CLIC like 1" Q96S66 1 108881885-108963527 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009087, HPA013210" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Plasma cells - Protein processing" 1 "Endoplasmic reticulum" "HPA009087: AB_1078532, HPA013210: AB_1846895" "unprognostic (2.95e-1)" "unprognostic (1.09e-1)" "prognostic favorable (1.33e-5)" "unprognostic (4.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.48e-1)" "unprognostic (2.40e-2)" "unprognostic (1.45e-1)" "unprognostic (5.30e-2)" "unprognostic (9.23e-2)" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (7.50e-2)" "unprognostic (1.74e-1)" "unprognostic (2.04e-1)" "unprognostic (4.68e-3)" "unprognostic (9.65e-2)" CNGA1 "CNCG, CNCG1, CNG1, RCNC1, RCNCa, RP49" ENSG00000198515 "Cyclic nucleotide gated channel subunit alpha 1" P29973 4 47935977-48016681 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "retina: 256.4" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 908.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA076168 Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 76: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 66: Photoreceptor cells - Visual perception" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA076168: AB_2686781" "unprognostic (2.68e-2)" "unprognostic (4.90e-2)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" "unprognostic (2.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-2)" "unprognostic (3.85e-2)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (3.18e-1)" "unprognostic (2.91e-1)" "unprognostic (5.48e-6)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (4.66e-2)" "unprognostic (8.23e-2)" CNGA3 "ACHM2, CCNC1, CCNCa, CNCG3, CNG3" ENSG00000144191 "Cyclic nucleotide gated channel subunit alpha 3" Q16281 2 98346188-98398601 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.8;intestine: 4.1;pituitary gland: 9.9;retina: 5.7" "Cell type enriched" "Detected in some" 11 "Cone photoreceptor cells: 34.0" "Cancer enriched" "Detected in some" 9 "glioma: 7.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Neuroblastoma: 1.5" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Group enriched" "Detected in some" 6 "basal ganglia: 1.8;hypothalamus: 1.9" "Not detected" "Not detected" "HPA049378, CAB079025" Approved Approved NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 22: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" 1 "CAB079025: , HPA049378: AB_2732551" "unprognostic (2.34e-2)" "unprognostic (1.83e-2)" "unprognostic (4.96e-2)" "unprognostic (4.81e-2)" "unprognostic (1.13e-1)" "unprognostic (2.18e-1)" "unprognostic (4.17e-4)" "unprognostic (4.65e-2)" "unprognostic (1.86e-3)" "unprognostic (2.88e-1)" "unprognostic (3.85e-3)" "unprognostic (8.98e-2)" "unprognostic (5.90e-2)" "unprognostic (3.71e-2)" CNGB1 "CNCG2, CNCG3L, CNGB1B, GAR1, GARP, RCNC2, RCNCb, RP45" ENSG00000070729 "Cyclic nucleotide gated channel subunit beta 1" Q14028 16 57882340-57971128 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Olfaction, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "retina: 581.5" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 348.3;Rod photoreceptor cells: 1033.4" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 11.1" "Colon - Colon enteroendocrine cells, Pancreas - Ductal cells, Skin - Outer root sheath cells" "Region enhanced" "Detected in some" "hypothalamus: 4.5" HPA060355 Approved "Plasma membrane,Cytosol" No NA "Cluster 76: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" Cytosol "Plasma membrane" "HPA060355: " "unprognostic (5.52e-3)" "unprognostic (4.51e-3)" "unprognostic (1.06e-1)" "unprognostic (2.73e-3)" "unprognostic (6.20e-2)" "unprognostic (1.76e-1)" "unprognostic (8.56e-4)" "unprognostic (3.08e-1)" "unprognostic (9.84e-2)" "unprognostic (2.83e-1)" "unprognostic (2.14e-4)" "unprognostic (5.42e-2)" "unprognostic (1.01e-3)" "unprognostic (5.20e-2)" "unprognostic (1.88e-1)" "unprognostic (4.57e-2)" "unprognostic (9.07e-2)" CNGB3 "ACHM1, ACHM3, RMCH" ENSG00000170289 "Cyclic nucleotide gated channel subunit beta 3" Q9NQW8 8 86553977-86743675 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.1;retina: 12.1" "Cell type enriched" "Detected in some" 22 "Cone photoreceptor cells: 249.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA057244 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" "HPA057244: AB_2683380" "unprognostic (5.35e-1)" "unprognostic (1.68e-3)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (3.62e-2)" "unprognostic (2.58e-1)" "unprognostic (6.25e-2)" "unprognostic (1.18e-1)" "unprognostic (2.91e-1)" "unprognostic (2.17e-1)" "unprognostic (3.82e-1)" "unprognostic (9.28e-2)" "unprognostic (2.77e-4)" "unprognostic (1.40e-4)" "unprognostic (1.66e-2)" "unprognostic (8.76e-2)" "unprognostic (1.84e-1)" CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 37.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 95.2;Distal enterocytes: 76.5;Rod photoreceptor cells: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Skeletal muscle - Skeletal myocytes, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 39: Retina & Testis - Cilium" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" COL11A1 "CO11A1, COLL6, DFNA37, STL2" ENSG00000060718 "Collagen type XI alpha 1 chain" P12107 1 102876467-103108872 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 19.5;retina: 9.3" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 523.1" "Cancer enhanced" "Detected in many" "breast cancer: 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 252.9" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058335 Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" No No 640000 "Cluster 34: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Endoplasmic reticulum" "HPA058335: AB_2683682" "unprognostic (2.60e-3)" "unprognostic (6.61e-4)" "unprognostic (9.58e-2)" "unprognostic (5.06e-5)" "unprognostic (2.83e-1)" "unprognostic (2.85e-2)" "unprognostic (6.03e-3)" "unprognostic (2.23e-3)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (1.94e-2)" "unprognostic (3.01e-12)" "unprognostic (1.27e-2)" "unprognostic (3.53e-1)" "unprognostic (3.54e-2)" "unprognostic (2.32e-2)" COL18A1 "KNO, KNO1, KS" ENSG00000182871 "Collagen type XVIII alpha 1 chain" P39060 21 45405165-45513720 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 548.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 371.4;Smooth muscle cells: 244.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Liver - Hepatocytes, Prostate - Endothelial cells, Skin - Fibroblast_1" "Region enriched" "Detected in all" 6 "cerebellum: 22.1" "Low region specificity" "Detected in all" "HPA030933, HPA036104" Supported Approved "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA 290000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 83: Liver - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" "Golgi apparatus" "HPA030933: , HPA036104: AB_2674943" "unprognostic (4.32e-2)" "unprognostic (1.20e-1)" "unprognostic (1.76e-2)" "unprognostic (3.47e-2)" "unprognostic (3.25e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.23e-3)" "unprognostic (9.93e-2)" "unprognostic (3.48e-1)" "unprognostic (2.77e-1)" "unprognostic (5.50e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-2)" "unprognostic (9.44e-2)" "unprognostic (9.10e-3)" "unprognostic (2.25e-3)" COL25A1 ENSG00000188517 "Collagen type XXV alpha 1 chain" Q9BXS0 4 108808725-109302752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 21.3;testis: 15.8" "Cell type enhanced" "Detected in many" "Early spermatids: 105.8;Inhibitory neurons: 262.8;Late spermatids: 53.0;Rod photoreceptor cells: 92.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 4.7" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029107 Approved "Endoplasmic reticulum,Vesicles,Cytosol" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 29: Forebrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 65: Neurons - Synaptic function" "Vesicles, Cytosol" "Endoplasmic reticulum" "HPA029107: AB_10600802" "unprognostic (1.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "unprognostic (8.87e-5)" "unprognostic (2.43e-2)" "unprognostic (3.20e-1)" "unprognostic (7.62e-3)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (3.53e-1)" "unprognostic (1.50e-2)" "unprognostic (1.17e-1)" "unprognostic (5.30e-3)" "unprognostic (2.82e-3)" "unprognostic (9.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" COL2A1 "AOM, SEDC, STL1" ENSG00000139219 "Collagen type II alpha 1 chain" P02458 12 47972967-48004554 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 18.6;pituitary gland: 8.9;retina: 5.4;stomach 1: 12.2" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 6.6;Early spermatids: 11.0;Enteroendocrine cells: 27.4;Granulosa cells: 9.7;Horizontal cells: 24.5;Late spermatids: 11.5;Muller glia cells: 21.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "liver cancer: 78.5" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002214, HPA055753" Approved Approved Nucleoplasm "Secreted to extracellular matrix" "No annotated function" No NA 1400000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 34: Testis cancer - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" Nucleoplasm "CAB002214: AB_563666, HPA055753: AB_2682908" "unprognostic (7.25e-2)" "unprognostic (1.20e-1)" "unprognostic (2.58e-1)" "unprognostic (3.44e-1)" "unprognostic (2.88e-2)" "unprognostic (3.08e-2)" "unprognostic (8.63e-2)" "unprognostic (2.77e-1)" "unprognostic (1.22e-1)" "unprognostic (3.12e-2)" "unprognostic (1.31e-4)" "unprognostic (2.64e-1)" "unprognostic (3.44e-3)" "unprognostic (1.89e-1)" "unprognostic (2.93e-1)" "unprognostic (2.07e-1)" "unprognostic (1.02e-1)" COL8A2 "FECD, FECD1, PPCD, PPCD2" ENSG00000171812 "Collagen type VIII alpha 2 chain" P25067 1 36095239-36125222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 11.6;Fibroblasts: 9.2;Hofbauer cells: 6.2;Macrophages: 7.3;Microglial cells: 8.1;Peritubular cells: 6.0;Smooth muscle cells: 7.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 4.5" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "spinal cord: 4.1" HPA049788 Uncertain Uncertain "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Connective tissue cells - ECM organization" "Golgi apparatus" "HPA049788: AB_2680882" "unprognostic (9.98e-2)" "unprognostic (3.26e-2)" "unprognostic (2.51e-2)" "unprognostic (8.41e-3)" "unprognostic (8.76e-2)" "prognostic favorable (9.44e-4)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (3.50e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.08e-2)" "unprognostic (6.77e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-3)" CPSF1 CPSF160 ENSG00000071894 "Cleavage and polyadenylation specific factor 1" Q10570 8 144393229-144409335 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065167, HPA068906" Supported Nucleoplasm No No "Cluster 33: Non-specific - ATP binding" "Cluster 78: Testis - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 49: Non-specific - Transcription" 9 Nucleoplasm "HPA065167: AB_2685426, HPA068906: AB_2686055" "unprognostic (6.37e-2)" "unprognostic (7.72e-2)" "unprognostic (2.41e-2)" "unprognostic (1.21e-1)" "unprognostic (2.93e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (1.05e-1)" "unprognostic (2.00e-3)" "unprognostic (6.45e-2)" "unprognostic (7.54e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (6.54e-5)" "unprognostic (2.40e-1)" "unprognostic (1.91e-1)" "unprognostic (7.90e-2)" "unprognostic (9.66e-3)" CRB1 "LCA8, RP12" ENSG00000134376 "Crumbs cell polarity complex component 1" P82279 1 197268204-197478455 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "retina: 72.4" "Cell type enhanced" "Detected in some" "Astrocytes: 445.3;Cone photoreceptor cells: 117.2;Inhibitory neurons: 124.5;Oligodendrocyte precursor cells: 262.7;Oligodendrocytes: 98.3;Rod photoreceptor cells: 149.5" "Cancer enriched" "Detected in single" 12 "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 7.8" "Lineage enriched" "Detected in single" 28 "granulocytes: 7.8" "Group enriched" "Detected in some" 5 "cervical cancer: 4.7;Sarcoma: 4.6" "Kidney - Ascending Loop of Henle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA061250, HPA063127" Approved Uncertain Vesicles "Secreted in brain" "No annotated function" NA NA "Cluster 76: Retina - Visual perception" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Astrocytes - Unknown function" 4 Vesicles "HPA061250: AB_2684458, HPA063127: AB_2684944" "unprognostic (1.96e-1)" "unprognostic (5.38e-3)" "unprognostic (2.92e-3)" "unprognostic (1.50e-2)" "unprognostic (5.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.38e-1)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (1.48e-3)" "unprognostic (2.59e-1)" "unprognostic (2.01e-3)" "unprognostic (1.78e-3)" "unprognostic (1.56e-1)" "unprognostic (3.36e-2)" "unprognostic (2.96e-1)" CRX "CORD2, CRD, LCA7, OTX3" ENSG00000105392 "Cone-rod homeobox" O43186 19 47819779-47843330 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding" "Cone-rod dystrophy, Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 124 "retina: 211.4" "Group enriched" "Detected in some" 6 "Bipolar cells: 139.8;Cone photoreceptor cells: 309.2;Rod photoreceptor cells: 415.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.2;Uterine cancer: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036762, HPA036763" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 74 "HPA036762: AB_10673663, HPA036763: AB_10670922" "unprognostic (1.09e-2)" "unprognostic (1.25e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-2)" "unprognostic (3.22e-2)" "unprognostic (2.69e-1)" "unprognostic (2.77e-2)" "unprognostic (3.71e-1)" "unprognostic (3.82e-2)" "unprognostic (1.33e-2)" "unprognostic (1.95e-10)" "unprognostic (9.27e-2)" "unprognostic (1.82e-2)" "unprognostic (8.94e-2)" "unprognostic (1.78e-3)" CRYAA "CRYA1, HSPB4" ENSG00000160202 "Crystallin alpha A" P02489 21 43169008-43172805 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Chaperone, Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "kidney: 83.6;retina: 99.6" "Cell type enhanced" "Detected in single" "Muller glia cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 8 "liver cancer: 3.5" "Region enhanced" "Detected in some" "hippocampal formation: 3.9" "Group enriched" "Detected in some" 16 "cerebral cortex: 51.6;hippocampal formation: 46.6" "HPA037737, HPA038430" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 34: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 10: Muller glia cells - Visual perception" 72 Cytosol Nucleoplasm "HPA037737: AB_2675639, HPA038430: AB_2732478" "unprognostic (3.68e-3)" CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 10335.0;skeletal muscle: 6727.5;tongue: 9029.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 7159.1;Proximal tubular cells: 7075.7;Schwann cells: 1861.7;Skeletal myocytes: 4337.4" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 236.2;ovarian cancer: 273.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA 370000 "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 38: Proximal tubular cells - Transmembrane transport" 18 "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" CRYBA1 CRYB1 ENSG00000108255 "Crystallin beta A1" P05813 17 29246859-29254494 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 1.2;Extravillous trophoblasts: 1.2;Syncytiotrophoblasts: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "hippocampal formation: 2.7;hypothalamus: 1.2;thalamus: 1.2" "Low region specificity" "Detected in all" HPA022016 Supported NA NA "Cluster 6: Non-specific - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 3: Basal prostatic cells - Lipid metabolism" 18 "HPA022016: AB_2732426" "unprognostic (2.89e-2)" "unprognostic (1.57e-1)" "unprognostic (8.75e-2)" "unprognostic (1.37e-1)" "unprognostic (9.62e-2)" "unprognostic (4.27e-3)" "unprognostic (2.08e-1)" "unprognostic (5.60e-2)" "unprognostic (2.52e-2)" "unprognostic (9.90e-2)" "unprognostic (5.85e-3)" "unprognostic (2.83e-1)" "unprognostic (2.09e-6)" "unprognostic (1.18e-1)" "unprognostic (1.86e-2)" "unprognostic (4.31e-2)" "unprognostic (6.84e-3)" CRYBA2 ENSG00000163499 "Crystallin beta A2" P53672 2 218990189-218993422 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 16.1;pituitary gland: 13.4" "Cell type enriched" "Detected in some" 4 "Enteroendocrine cells: 886.3" "Cancer enriched" "Detected in some" 15 "pancreatic cancer: 16.0" "Group enriched" "Detected in many" 6 "midbrain: 23.4;pons: 10.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 4.7;Neuroblastoma: 4.3" "Pancreas - Alpha cells, Prostate - Prostate glandular cells" "Region enhanced" "Detected in some" "pons and medulla: 4.3" "Low region specificity" "Detected in many" HPA062293 Supported NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" 21 "HPA062293: AB_2732680" "unprognostic (5.29e-2)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (4.19e-1)" "unprognostic (6.19e-2)" "unprognostic (1.77e-1)" "unprognostic (2.72e-1)" "unprognostic (1.66e-2)" "unprognostic (3.75e-1)" "prognostic favorable (7.62e-4)" "unprognostic (2.91e-1)" "unprognostic (1.90e-1)" "unprognostic (2.19e-1)" CRYBA4 ENSG00000196431 "Crystallin beta A4" P53673 22 26621963-26630669 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 1.4;testis: 1.1" "Cell type enhanced" "Detected in some" "Early spermatids: 4.9;granulocytes: 1.7;NK-cells: 1.1;Plasma cells: 2.0;Spermatogonia: 4.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.0;testis cancer: 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 4.7;hippocampal formation: 4.3" HPA071178 Supported NA NA "Cluster 63: Testis - Spermatid development" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 77: Plasma cells - Protein processing" 10 "HPA071178: AB_2686354" "unprognostic (6.69e-2)" "unprognostic (3.94e-3)" "unprognostic (5.61e-5)" "unprognostic (1.74e-2)" "unprognostic (5.57e-2)" "unprognostic (2.32e-2)" "unprognostic (2.71e-1)" "unprognostic (7.92e-2)" "unprognostic (3.50e-2)" "unprognostic (1.85e-1)" "unprognostic (9.05e-6)" "unprognostic (2.86e-1)" "unprognostic (1.20e-6)" "unprognostic (1.87e-2)" "unprognostic (7.23e-2)" "unprognostic (7.71e-2)" "unprognostic (3.70e-1)" CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618027 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.4" "Cell type enriched" "Detected in some" 15 "Hofbauer cells: 73.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "intermediate monocyte: 10.3;non-classical monocyte: 7.6" "Lineage enriched" "Detected in many" 7 "monocytes: 10.3" "Cancer enriched" "Detected in some" 6 "Myeloma: 12.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Skeletal muscle - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003448, CAB010058" Supported NA NA 89000 "Cluster 40: Monocytes - Innate immune response" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" 6 "CAB010058: AB_668166, HPA003448: AB_2732396" "unprognostic (1.31e-1)" "unprognostic (5.56e-3)" "unprognostic (1.39e-2)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-3)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-2)" CRYBB2 "CCA2, CRYB2, CRYB2A" ENSG00000244752 "Crystallin beta B2" P43320 22 25212564-25231870 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1" "Cell type enhanced" "Detected in some" "Astrocytes: 1.9;Excitatory neurons: 2.3;Late spermatids: 8.0;Lymphatic endothelial cells: 3.2;Microglial cells: 1.8" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Region enhanced" "Detected in some" "hippocampal formation: 1.7" "Low region specificity" "Detected in many" HPA043749 Supported Approved Nucleoplasm NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 63: Late spermatids - Spermatogenesis" 5 Nucleoplasm "HPA043749: AB_2678652" "unprognostic (1.28e-1)" "unprognostic (2.71e-2)" "unprognostic (4.09e-2)" "unprognostic (1.95e-1)" "unprognostic (5.06e-2)" "unprognostic (7.04e-2)" "unprognostic (8.57e-3)" "unprognostic (9.51e-3)" "unprognostic (8.55e-2)" "unprognostic (2.46e-2)" "unprognostic (4.13e-2)" "unprognostic (2.01e-1)" "unprognostic (1.73e-5)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (9.89e-3)" CRYBB3 CRYB3 ENSG00000100053 "Crystallin beta B3" P26998 22 25199858-25207359 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 4 "Muller glia cells: 3.8;Oocytes: 5.1;Proximal tubular cells: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA055840 Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 5 Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA055840: AB_2682939" "unprognostic (1.36e-2)" "unprognostic (6.27e-4)" "unprognostic (6.30e-3)" "unprognostic (5.34e-2)" "unprognostic (8.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.45e-2)" "unprognostic (2.07e-2)" "unprognostic (4.15e-2)" "unprognostic (8.28e-2)" "unprognostic (2.40e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-3)" CRYGB CRYG2 ENSG00000182187 "Crystallin gamma B" P07316 2 208142573-208146158 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Early spermatids: 1.2" "Group enriched" "Detected in some" 6 "ovarian cancer: 1.1;testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "hippocampal formation: 3.3;hypothalamus: 2.2;thalamus: 2.0" HPA043386 Supported Approved Vesicles,Cytosol NA NA "Cluster 1: Neuronal - Visual perception" "Cluster 21: Early spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA043386: " "unprognostic (6.73e-2)" "unprognostic (1.31e-1)" CRYGC CRYG3 ENSG00000163254 "Crystallin gamma C" P07315 2 208128137-208129828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 1.6" "Group enriched" "Detected in some" 15 "Early spermatids: 2.7;granulocytes: 1.6;Late spermatids: 2.7;Spermatocytes: 1.8;Spermatogonia: 3.1" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.8;ovarian cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "hippocampal formation: 3.2;hypothalamus: 1.5;thalamus: 1.2" "Group enriched" "Detected in some" 17 "cerebral cortex: 1.5;hippocampal formation: 1.7" HPA043386 Supported Approved Vesicles,Cytosol NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 31: Spermatocytes - Spermatogenesis" 4 "Vesicles, Cytosol" "HPA043386: " "unprognostic (1.89e-1)" "unprognostic (2.89e-1)" CRYGD CRYG4 ENSG00000118231 "Crystallin gamma D" P07320 2 208121607-208124524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.1;ovary: 7.6" "Group enriched" "Detected in some" 5 "Early spermatids: 12.3;Muller glia cells: 33.7;Ovarian stromal cells: 35.3" "Cancer enhanced" "Detected in some" "testis cancer: 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 2.5" "Not detected" "Not detected" "HPA041269, HPA043386" Supported Approved Vesicles,Cytosol NA NA "Cluster 64: Neuronal - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 6: Ovarian stromal cells - Transcription" "Vesicles, Cytosol" "HPA041269: AB_2732491, HPA043386: " "unprognostic (4.49e-2)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" CRYGS CRYG8 ENSG00000213139 "Crystallin gamma S" P22914 3 186538441-186546702 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.5" "Cell type enhanced" "Detected in some" "Astrocytes: 5.0;Excitatory neurons: 5.2;Inhibitory neurons: 5.8;Microglial cells: 5.4;Oligodendrocyte precursor cells: 5.7;Oligodendrocytes: 7.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA035103, HPA063539" Supported Uncertain Cytosol NA NA "Cluster 28: Neuronal - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 56: Non-specific - Sensory perception" "Cluster 59: Suprabasal keratinocytes - Cornification" 1 Cytosol "HPA035103: AB_10696367, HPA063539: " "unprognostic (5.52e-4)" "unprognostic (1.29e-3)" "unprognostic (1.44e-2)" "unprognostic (5.45e-2)" "unprognostic (4.90e-2)" "unprognostic (5.85e-2)" "unprognostic (4.79e-2)" "unprognostic (1.73e-2)" "unprognostic (4.76e-2)" "unprognostic (1.12e-1)" "unprognostic (5.84e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.72e-9)" "unprognostic (1.10e-1)" "unprognostic (9.53e-2)" "unprognostic (3.67e-1)" "prognostic favorable (2.73e-4)" CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4419.8;choroid plexus: 4010.9" "Cell type enhanced" "Detected in all" "Langerhans cells: 22281.6;Schwann cells: 10946.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4979.2;intermediate monocyte: 6434.2;myeloid DC: 7977.6;non-classical monocyte: 4321.2;plasmacytoid DC: 4438.0" "Group enriched" "Detected in all" 9 "dendritic cells: 7977.6;monocytes: 6434.2" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skin - Fibroblast_2, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" "Enzyme inhibitor" NA NA 1040000000 2800000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 28: Dendritic cells - Antigen presentation" 1 "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" CTNNA1 CAP102 ENSG00000044115 "Catenin alpha 1" P35221 5 138610967-138935034 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 411.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021089, HPA046119, HPA063535" Supported Supported "Plasma membrane,Cell Junctions" NA NA 57000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 45: Non-specific - Mixed function" 10 "Plasma membrane, Cell Junctions" "CAB021089: AB_10123543, HPA046119: AB_2679547, HPA063535: AB_2685033" "unprognostic (2.25e-3)" "unprognostic (3.32e-2)" "unprognostic (2.82e-3)" "unprognostic (1.80e-1)" "unprognostic (8.40e-2)" "unprognostic (2.35e-1)" "unprognostic (1.66e-3)" "unprognostic (4.83e-2)" "unprognostic (2.28e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.02e-4)" "unprognostic (6.18e-2)" "prognostic favorable (7.34e-7)" "unprognostic (1.54e-1)" "unprognostic (2.31e-1)" "unprognostic (7.62e-2)" "unprognostic (1.04e-1)" CTNNB1 "armadillo, beta-catenin, CTNNB" ENSG00000168036 "Catenin beta 1" P35222 3 41194741-41260096 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway" Activator "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 570.0;Syncytiotrophoblasts: 463.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000108, CAB001950, HPA029159, HPA029160" Supported Enhanced "Plasma membrane" NA NA 2000000 "Cluster 33: Non-specific - ATP binding" "Cluster 62: Connective tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 29: Monocytes - Innate immune response" 81 "Plasma membrane" "CAB000108: , CAB001950: , HPA029159: AB_10599619, HPA029160: AB_10600996" "unprognostic (2.47e-1)" "unprognostic (3.48e-2)" "prognostic favorable (7.54e-4)" "unprognostic (1.61e-1)" "unprognostic (9.55e-2)" "unprognostic (1.05e-2)" "unprognostic (3.20e-3)" "unprognostic (2.79e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-2)" "unprognostic (1.88e-2)" "unprognostic (9.05e-2)" "unprognostic (1.97e-3)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" "unprognostic (2.61e-1)" "unprognostic (9.79e-2)" CX3CR1 "CCRL1, CMKBRL1, CMKDR1, GPR13, V28" ENSG00000168329 "C-X3-C motif chemokine receptor 1" P49238 3 39263495-39281735 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.3" "Cell type enhanced" "Detected in some" "Langerhans cells: 37.8;Macrophages: 46.2;Microglial cells: 169.1;NK-cells: 184.9" "Cancer enriched" "Detected in many" 4 "glioma: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 451.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 6 "Myeloma: 16.7" "Heart muscle - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032478, HPA046587" Approved Supported "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 33: Brain - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane" "CAB032478: AB_638830, HPA046587: AB_2679708" "unprognostic (2.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.65e-1)" "unprognostic (2.42e-2)" "unprognostic (6.52e-2)" "unprognostic (3.01e-3)" "unprognostic (2.64e-1)" "unprognostic (1.16e-2)" "unprognostic (3.98e-2)" "unprognostic (1.57e-3)" "unprognostic (1.13e-2)" "unprognostic (1.04e-1)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (8.59e-2)" "unprognostic (7.71e-3)" "unprognostic (1.12e-1)" CYP4V2 CYP4AH1 ENSG00000145476 "Cytochrome P450 family 4 subfamily V member 2" Q6ZWL3 4 186191567-186213463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Monooxygenase, Oxidoreductase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 110.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029122 Approved Approved "Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 10: Muller glia cells - Visual perception" "Nuclear speckles" "HPA029122: AB_10601806" "unprognostic (1.65e-1)" "unprognostic (5.37e-2)" "unprognostic (2.35e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.66e-2)" "unprognostic (5.84e-2)" "unprognostic (2.05e-1)" "unprognostic (6.49e-2)" "unprognostic (9.89e-2)" "prognostic favorable (1.49e-7)" "unprognostic (3.25e-2)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" DCN "DSPG2, SLRR1B" ENSG00000011465 Decorin P07585 12 91140484-91183217 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Corneal dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 3461.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1244.1;Fibroblasts: 6900.8;Leydig cells: 6252.9;Ovarian stromal cells: 2294.9;Peritubular cells: 1873.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 24.5" "Lineage enriched" "Detected in single" 35 "granulocytes: 24.5" "Cancer enriched" "Detected in many" 5 "Rhabdoid: 724.2" "Breast - Fibroblasts, Colon - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "spinal cord: 718.9" "HPA003315, CAB017118, HPA064736, CAB068930" Enhanced "Secreted to extracellular matrix" "No annotated function" NA NA 1900000 "Cluster 46: Basophils - Proteolysis" "Cluster 62: Connective tissue - ECM organization" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "CAB017118: , CAB068930: AB_425394, HPA003315: AB_1078639, HPA064736: AB_2685340" "unprognostic (1.73e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" "unprognostic (2.68e-1)" "unprognostic (1.98e-1)" "unprognostic (6.12e-2)" "unprognostic (1.65e-1)" "unprognostic (5.15e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (3.06e-3)" "unprognostic (5.37e-2)" "unprognostic (1.59e-3)" "unprognostic (7.56e-3)" DHDDS "DS, FLJ13102, hCIT, HDS, RP59" ENSG00000117682 "Dehydrodolichyl diphosphate synthase subunit" Q86SQ9 1 26432282-26471306 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant, Epilepsy, Intellectual disability, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 125.7;Rod photoreceptor cells: 121.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026721, HPA026727" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 21: Early spermatids - Spermatogenesis" 1 "Plasma membrane" "HPA026721: AB_1847643, HPA026727: AB_1847644" "unprognostic (1.11e-2)" "unprognostic (5.43e-2)" "unprognostic (5.12e-2)" "unprognostic (9.81e-2)" "unprognostic (6.71e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-3)" "unprognostic (3.81e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-2)" "unprognostic (4.51e-2)" "unprognostic (3.40e-2)" "prognostic favorable (4.08e-7)" "unprognostic (9.42e-2)" "unprognostic (2.85e-1)" "unprognostic (2.22e-1)" "unprognostic (2.95e-1)" DHX38 "DDX38, hPrp16, KIAA0224, PRP16, PRPF16" ENSG00000140829 "DEAH-box helicase 38" Q92620 16 72093613-72112912 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041347, HPA041604" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 55: Non-specific - Transcription" 5 Nucleoplasm "HPA041347: AB_10796571, HPA041604: AB_2677577" "unprognostic (2.38e-1)" "unprognostic (1.89e-1)" "unprognostic (1.24e-2)" "unprognostic (3.25e-2)" "unprognostic (1.07e-1)" "unprognostic (1.01e-1)" "unprognostic (6.32e-3)" "unprognostic (8.50e-3)" "unprognostic (6.97e-2)" "unprognostic (1.45e-1)" "unprognostic (7.92e-2)" "unprognostic (1.28e-3)" "unprognostic (4.20e-3)" "unprognostic (2.68e-1)" "unprognostic (9.46e-2)" "unprognostic (2.40e-1)" "unprognostic (2.40e-2)" DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease variant, Dwarfism, Intellectual disability, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 35.3;Excitatory neurons: 13.6;Inhibitory neurons: 14.9;Oligodendrocytes: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.9" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037487, HPA057526" Approved Supported Mitochondria No Yes "Cluster 16: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cell proliferation" Mitochondria "HPA037487: AB_10672493, HPA057526: AB_2683456" "unprognostic (1.79e-1)" "unprognostic (1.35e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-3)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (4.50e-5)" "unprognostic (3.36e-2)" "unprognostic (4.70e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-2)" "unprognostic (3.29e-4)" "unprognostic (1.09e-10)" "unprognostic (3.43e-2)" "unprognostic (1.98e-1)" "unprognostic (9.36e-2)" "unprognostic (1.23e-2)" DNM1L "DRP1, DVLP, DYMPLE, HDYNIV, VPS1" ENSG00000087470 "Dynamin 1 like" O00429 12 32679200-32745650 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Biological rhythms, Endocytosis, Necrosis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009952, HPA039324" Approved Supported Vesicles,Cytosol NA NA 2000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Non-specific - Unknown function" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" 7 Cytosol Vesicles "CAB009952: AB_2093533, HPA039324: AB_2676443" "unprognostic (2.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (5.09e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.27e-6)" "unprognostic (8.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.04e-2)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (7.48e-2)" "unprognostic (1.57e-2)" DNMBP "ARHGEF36, KIAA1010, Tuba" ENSG00000107554 "Dynamin binding protein" Q6XZF7 10 99875577-100009947 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 149.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037878, HPA058216" Uncertain Approved "Nucleoli,Nuclear bodies,Golgi apparatus,Cytosol" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 29: Monocytes - Innate immune response" 1 "Nucleoli, Golgi apparatus, Cytosol" "Nuclear bodies" "HPA037878: AB_10675622, HPA058216: AB_2683640" "unprognostic (3.25e-1)" "unprognostic (8.19e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.95e-6)" "unprognostic (3.92e-2)" "unprognostic (4.13e-1)" "unprognostic (9.79e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.02e-1)" "unprognostic (8.67e-3)" "unprognostic (4.03e-2)" "unprognostic (5.07e-3)" "unprognostic (6.52e-2)" "unprognostic (4.95e-2)" "unprognostic (1.28e-1)" "prognostic favorable (6.15e-4)" DRAM2 "MGC54289, PRO180, RP5-1180E21.1, TMEM77, WWFQ154" ENSG00000156171 "DNA damage regulated autophagy modulator 2" Q6UX65 1 111117163-111140203 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 191.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018036, HPA061701" Supported Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 25: Non-specific - Ribosome" "Cluster 73: B-cells - B-cell function" "Golgi apparatus, Vesicles" "HPA018036: AB_1858134, HPA061701: AB_2684590" "unprognostic (9.38e-3)" "unprognostic (1.58e-2)" "unprognostic (2.16e-3)" "unprognostic (5.22e-2)" "unprognostic (1.12e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.57e-3)" "prognostic unfavorable (6.43e-4)" "unprognostic (2.69e-1)" "unprognostic (4.37e-3)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (1.77e-3)" EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 342.8;Cytotrophoblasts: 1342.6;Fibroblasts: 310.2;Lymphatic endothelial cells: 378.4;Mesothelial cells: 769.6;Syncytiotrophoblasts: 824.5" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 474.4" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblast_2, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" "Growth factor" NA NA 1900000000 "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 46: Brainstem - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 24: Cytotrophoblasts - Mitochondria" 27 Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 143.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 160.7;Club cells: 114.2;Glandular and luminal cells: 167.1;Ionocytes: 159.4;Squamous epithelial cells: 159.9;Suprabasal keratinocytes: 193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Prostate - Urothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 11 "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" EPO EP ENSG00000130427 Erythropoietin P01588 7 100720468-100723700 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Erythrocyte maturation" Hormone "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 46.0" "Group enriched" "Detected in some" 4 "Exocrine glandular cells: 6.4;Extravillous trophoblasts: 16.8;Hepatocytes: 18.5" "Group enriched" "Detected in many" 5 "liver cancer: 2.7;renal cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" CAB010336 Supported "Secreted to blood" Hormone NA NA 12300 "Cluster 83: Liver - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 62: Hepatocytes - Metabolism" 2 "CAB010336: AB_2098408" "unprognostic (2.93e-1)" "unprognostic (1.57e-2)" "unprognostic (1.08e-3)" "unprognostic (7.30e-2)" "unprognostic (1.09e-1)" "unprognostic (1.78e-3)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.52e-2)" "unprognostic (5.16e-2)" "unprognostic (9.70e-2)" "unprognostic (2.44e-3)" "unprognostic (3.31e-1)" "prognostic unfavorable (2.18e-6)" "unprognostic (4.80e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-2)" "unprognostic (3.34e-1)" ERCC6 "ARMD5, CKN2, CSB, RAD26" ENSG00000225830 "ERCC excision repair 6, chromatin remodeling factor" "P0DP91, Q03468" 10 49454168-49539538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Age-related macular degeneration, Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Intellectual disability, Premature ovarian failure, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" HPA071297 Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 16: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 55: Non-specific - Transcription" 2 Nucleoplasm "Nuclear bodies" "HPA071297: AB_2732177" "unprognostic (1.92e-2)" "unprognostic (1.85e-1)" "unprognostic (9.79e-3)" "unprognostic (7.26e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-2)" "unprognostic (3.03e-2)" "unprognostic (2.99e-2)" "unprognostic (1.71e-2)" "unprognostic (1.13e-1)" "unprognostic (1.80e-1)" "unprognostic (4.57e-2)" "unprognostic (1.04e-1)" "unprognostic (8.61e-2)" "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" ESPN DFNB36 ENSG00000187017 Espin B1AK53 1 6424776-6461367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing Actin-binding "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 125.7;retina: 114.4;testis: 140.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 176.1;Late spermatids: 476.6;Muller glia cells: 239.5;Paneth cells: 138.6;Proximal enterocytes: 514.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 29.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 92.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 4.0" "HPA028674, HPA060220" Enhanced Approved Vesicles NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 5: Enterocytes - Absorption" Vesicles "HPA028674: AB_10601316, HPA060220: AB_2684224" "unprognostic (5.06e-2)" "unprognostic (1.18e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-1)" "unprognostic (2.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (2.28e-1)" "unprognostic (1.16e-1)" "unprognostic (5.71e-2)" "unprognostic (7.48e-3)" "unprognostic (5.53e-2)" "unprognostic (6.26e-3)" "unprognostic (5.51e-2)" "unprognostic (1.16e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-2)" FAM161A "FLJ13305, RP28" ENSG00000170264 "FAM161 centrosomal protein A" Q3B820 2 61824848-61854143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 28.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.4;Early spermatids: 204.5;Late spermatids: 300.9;Rod photoreceptor cells: 368.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032119 Approved NA Yes "Cluster 39: Retina & Testis - Cilium" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 66: Photoreceptor cells - Visual perception" 118 "HPA032119: AB_10602806" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (4.23e-2)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "unprognostic (1.56e-5)" "unprognostic (7.62e-2)" "unprognostic (1.72e-1)" "unprognostic (2.14e-2)" "unprognostic (4.35e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (5.33e-2)" "unprognostic (3.93e-1)" "unprognostic (8.08e-3)" "unprognostic (7.04e-2)" FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Fibroblasts: 215.1;Leydig cells: 615.0;Peritubular cells: 773.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.7" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Pancreas - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" NA NA 12000000 "Cluster 41: Basophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 11 "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" FRMD7 "FLJ43346, NYS, NYS1" ENSG00000165694 "FERM domain containing 7" Q6ZUT3 X 132076990-132128020 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Neurogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 2.8;kidney: 2.6;smooth muscle: 2.1" "Cell type enriched" "Detected in single" 20 "Distal tubular cells: 9.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells, Liver - Hepatocytes" "Region enriched" "Detected in many" 28 "olfactory bulb: 65.7" "Region enriched" "Detected in all" 5 "olfactory bulb: 27.6" HPA000886 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 51: Thyroid gland - Unknown function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 1 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA000886: AB_1079269" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" "unprognostic (3.07e-1)" "unprognostic (4.02e-2)" "unprognostic (1.64e-2)" "unprognostic (2.28e-1)" "unprognostic (2.18e-2)" "unprognostic (3.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.00e-1)" FSCN2 "RFSN, RP30" ENSG00000186765 "Fascin actin-bundling protein 2, retinal" O14926 17 81528377-81537130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 4.4;retina: 8.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.1;Cone photoreceptor cells: 22.1;Exocrine glandular cells: 8.9;Rod photoreceptor cells: 22.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA079270 Enhanced NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" 3 "HPA079270: " "unprognostic (3.50e-3)" "unprognostic (6.55e-2)" "unprognostic (2.73e-4)" "unprognostic (1.08e-3)" "unprognostic (1.11e-2)" "unprognostic (2.11e-2)" "unprognostic (6.49e-3)" "unprognostic (3.49e-1)" "unprognostic (1.64e-3)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (3.21e-1)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (1.74e-1)" "unprognostic (2.11e-1)" FTL "MGC71996, NBIA3" ENSG00000087086 "Ferritin light chain" P02792 19 48965309-48966879 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Iron storage" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 14070.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 29778.7;Hofbauer cells: 77810.9;Kupffer cells: 52544.7;Macrophages: 30310.5;monocytes: 24547.4;Proximal tubular cells: 53178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 125828.8;monocytes: 102246.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020769, HPA041602" Enhanced Approved Cytosol NA NA 170000000 "Cluster 29: Non-specific - Unknown function" "Cluster 11: Liver - Plasma proteins" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Macrophages - Innate immune response" 13 Cytosol "CAB020769: , HPA041602: AB_2677575" "unprognostic (2.95e-1)" "unprognostic (2.64e-2)" "unprognostic (1.31e-1)" "unprognostic (1.56e-3)" "unprognostic (7.48e-2)" "unprognostic (5.28e-2)" "unprognostic (2.16e-3)" "unprognostic (6.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.08e-1)" "unprognostic (2.66e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (4.40e-5)" "unprognostic (1.32e-1)" "unprognostic (2.43e-2)" "unprognostic (2.30e-2)" "unprognostic (1.87e-2)" FYCO1 "FLJ13335, ZFYVE7" ENSG00000163820 "FYVE and coiled-coil domain autophagy adaptor 1" Q9BQS8 3 45917903-45995824 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 253.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.8;Skeletal myocytes: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Lung - Fibroblast_1, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035526, HPA057966" Uncertain Enhanced Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 32: Smooth muscle cells - Muscle contraction" 9 Vesicles "HPA035526: AB_10672867, HPA057966: AB_2683567" "unprognostic (2.45e-1)" "unprognostic (6.62e-2)" "unprognostic (6.97e-3)" "unprognostic (1.14e-3)" "unprognostic (7.65e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-2)" "unprognostic (4.53e-3)" "unprognostic (5.85e-2)" "unprognostic (8.85e-2)" "unprognostic (2.36e-1)" "unprognostic (2.98e-1)" "prognostic favorable (3.33e-11)" "unprognostic (2.90e-1)" "unprognostic (1.42e-1)" "unprognostic (2.89e-2)" "unprognostic (6.99e-2)" FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 115.9" "Cell type enhanced" "Detected in many" "Adipocytes: 82.2;Basal prostatic cells: 29.7;Collecting duct cells: 27.2;Endothelial cells: 61.4;Fibroblasts: 32.6;Skeletal myocytes: 28.3;Smooth muscle cells: 27.3" "Cancer enhanced" "Detected in all" "renal cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042328, HPA074833" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "Plasma membrane" Nucleoplasm "HPA042328: AB_10962494, HPA074833: AB_2686716" "unprognostic (6.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.22e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.05e-2)" "unprognostic (9.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.97e-1)" GCNT2 "bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3" ENSG00000111846 "Glucosaminyl (N-acetyl) transferase 2 (I blood group)" Q8N0V5 6 10492223-10629368 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.0" "Cell type enriched" "Detected in many" 7 "Oocytes: 672.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 17.5;testis cancer: 19.4" "Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Stomach - Parietal cells, Testis - Spermatogonia" "Region enriched" "Detected in all" 4 "basal ganglia: 61.2" "Low region specificity" "Detected in many" HPA026776 Approved Approved "Golgi apparatus" No No 750000 "Cluster 29: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 44: Oocytes - Unknown function" "Golgi apparatus" "HPA026776: AB_1849573" "unprognostic (2.47e-1)" "unprognostic (6.87e-3)" "unprognostic (3.12e-1)" "unprognostic (1.42e-2)" "unprognostic (9.31e-2)" "unprognostic (2.51e-1)" "unprognostic (4.11e-2)" "unprognostic (2.39e-1)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (6.28e-4)" "unprognostic (3.96e-2)" "unprognostic (1.58e-3)" "unprognostic (6.54e-2)" "unprognostic (6.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Deafness, Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 3.1;Fibroblasts: 2.2;Mesothelial cells: 2.8;Oligodendrocyte precursor cells: 6.6;Oocytes: 2.2;Pancreatic endocrine cells: 1.7;Spermatogonia: 2.1" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 31.8;Neuroblastoma: 10.7;Sarcoma: 11.2;testis cancer: 14.6" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblast_2, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enriched" "Detected in single" 7 "midbrain: 2.0" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" Cytokine NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" GJA3 "CX46, CZP3" ENSG00000121743 "Gap junction protein alpha 3" Q9Y6H8 13 20138255-20161052 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 7.5;parathyroid gland: 3.9;placenta: 2.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 15.9;Oocytes: 2.9;Sertoli cells: 5.4;Spermatogonia: 3.2" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.3;melanoma: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 5.7" "Kidney - Podocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA014821 Supported NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 5: Rhabdoid - Unknown function" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA014821: AB_2669097" "unprognostic (2.32e-1)" "unprognostic (1.01e-1)" "unprognostic (4.37e-2)" "unprognostic (2.58e-3)" "unprognostic (2.98e-2)" "unprognostic (1.04e-2)" "unprognostic (6.87e-3)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" "unprognostic (7.52e-2)" "unprognostic (7.70e-2)" "unprognostic (4.02e-2)" "unprognostic (9.65e-8)" "unprognostic (2.87e-1)" "unprognostic (1.91e-1)" "unprognostic (2.55e-2)" "unprognostic (8.04e-3)" GJA8 "CAE, CAE1, CX50, CZP1" ENSG00000121634 "Gap junction protein alpha 8" P48165 1 147902795-147909269 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 5.7" "Group enriched" "Detected in some" 4 "Early spermatids: 18.5;Spermatocytes: 33.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014715, HPA062940" Enhanced NA NA "Cluster 42: Testis - Spermatogenesis" "Cluster 15: Kidney cancer - Membrane components" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 105 "HPA014715: AB_2732411, HPA062940: AB_2732693" "unprognostic (3.73e-2)" "unprognostic (2.35e-1)" GNAT1 CSNBAD3 ENSG00000114349 "G protein subunit alpha transducin 1" P11488 3 50191610-50197696 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Transducer "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 902 "retina: 1086.0" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 1787.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in some" 6 "hippocampal formation: 6.5" "Not detected" "Not detected" HPA045393 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA045393: AB_2679310" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "unprognostic (8.56e-3)" "unprognostic (3.32e-2)" "unprognostic (2.13e-1)" "unprognostic (7.72e-2)" "unprognostic (2.82e-3)" "unprognostic (6.10e-2)" "unprognostic (1.07e-1)" "unprognostic (1.87e-1)" "unprognostic (3.02e-1)" "unprognostic (9.48e-3)" GNB3 ENSG00000111664 "G protein subunit beta 3" P16520 12 6839954-6847393 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "retina: 413.5" "Cell type enriched" "Detected in many" 4 "Cone photoreceptor cells: 2390.7" "Cancer enhanced" "Detected in some" "testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 16.7" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 6.9" HPA040736 Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 76: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" "Golgi apparatus" "HPA040736: AB_2677106" "unprognostic (3.86e-2)" "unprognostic (1.58e-1)" "unprognostic (4.96e-2)" "unprognostic (8.75e-2)" "unprognostic (2.53e-2)" "unprognostic (5.74e-3)" "unprognostic (5.98e-2)" "unprognostic (4.43e-3)" "unprognostic (1.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.25e-5)" "unprognostic (3.21e-2)" "unprognostic (4.77e-11)" "unprognostic (2.43e-1)" "unprognostic (6.48e-2)" "unprognostic (1.36e-1)" "unprognostic (1.07e-2)" GPR143 OA1 ENSG00000101850 "G protein-coupled receptor 143" P51810 X 9725346-9786297 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.0" "Cell type enriched" "Detected in many" 4 "Melanocytes: 190.7" "Cancer enriched" "Detected in all" 9 "melanoma: 84.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.1" "Lineage enriched" "Detected in single" 19 "granulocytes: 3.1" "Cancer enriched" "Detected in many" 5 "skin cancer: 74.2" "Adipose visceral - Mesothelial cells, Skin - Melanocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003648 Enhanced NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 "HPA003648: AB_2667028" "unprognostic (4.60e-2)" "prognostic favorable (8.73e-4)" "unprognostic (7.43e-3)" "unprognostic (5.41e-2)" "unprognostic (4.62e-3)" "unprognostic (2.00e-2)" "unprognostic (3.05e-1)" "unprognostic (2.64e-3)" "unprognostic (3.78e-1)" "unprognostic (5.89e-2)" "unprognostic (8.18e-2)" "unprognostic (8.40e-2)" "prognostic favorable (2.45e-5)" "unprognostic (2.75e-1)" "unprognostic (2.07e-1)" "unprognostic (8.76e-2)" "unprognostic (1.59e-2)" GPR179 "CSNB1E, GPR158L1" ENSG00000277399 "G protein-coupled receptor 179" 17 38324571-38343956 "Human disease related genes, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "retina: 13.4" "Cell type enriched" "Detected in some" 29 "Bipolar cells: 75.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA017885 Uncertain NA NA "Cluster 76: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" "HPA017885: AB_2279357" "unprognostic (1.65e-1)" "unprognostic (2.27e-1)" "unprognostic (1.24e-4)" "unprognostic (8.89e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.10e-1)" "unprognostic (3.04e-2)" "unprognostic (4.76e-2)" "unprognostic (2.34e-2)" "unprognostic (6.57e-3)" "unprognostic (5.31e-2)" "unprognostic (5.09e-10)" "unprognostic (6.18e-2)" "unprognostic (2.31e-1)" "unprognostic (1.62e-2)" "unprognostic (3.41e-4)" GRHL2 "BOM, DFNA28, FLJ13782, TFCP2L3" ENSG00000083307 "Grainyhead like transcription factor 2" Q6ISB3 8 101492439-101669726 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 27.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 29.0;Prostatic glandular cells: 52.4;Suprabasal keratinocytes: 28.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Liver - Cholangiocyte, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004820, HPA062839" Uncertain Supported Nucleoplasm NA NA "Cluster 13: Skin - Cornification" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Prostatic glandular cells - Transcription" 4 Nucleoplasm "HPA004820: AB_1857928, HPA062839: AB_2684878" "prognostic unfavorable (6.43e-4)" "unprognostic (2.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.68e-1)" "unprognostic (4.79e-2)" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (2.61e-2)" "unprognostic (8.29e-4)" "unprognostic (4.54e-3)" "unprognostic (2.64e-1)" "unprognostic (1.08e-1)" "unprognostic (1.03e-2)" GRK1 "GPRK1, RHOK, RK" ENSG00000185974 "G protein-coupled receptor kinase 1" Q15835 13 113667219-113737736 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" "Kinase, Serine/threonine-protein kinase, Transferase" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "retina: 41.3" "Group enriched" "Detected in some" 9 "Cone photoreceptor cells: 34.0;Rod photoreceptor cells: 82.4" "Cancer enriched" "Detected in single" 5 "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "prostate cancer: 1.1" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035200, HPA059376" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 60: Prostate cancer - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "HPA035200: AB_2674515, HPA059376: AB_2683996" "unprognostic (7.93e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-1)" "unprognostic (1.24e-5)" "unprognostic (1.76e-3)" "unprognostic (1.53e-1)" "unprognostic (3.59e-2)" "unprognostic (2.21e-2)" "unprognostic (1.84e-3)" "unprognostic (2.00e-2)" "unprognostic (4.02e-2)" "unprognostic (6.91e-2)" "unprognostic (6.18e-2)" "unprognostic (6.11e-2)" GRM6 "CSNB1B, GPRC1F, mGlu6, MGLUR6" ENSG00000113262 "Glutamate metabotropic receptor 6" O15303 5 178977587-178996206 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Receptor, Transducer" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 57 "retina: 41.3" "Cell type enriched" "Detected in some" 35 "Bipolar cells: 482.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Brain cancer: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014511 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" "HPA014511: AB_2669025" "unprognostic (1.85e-1)" "unprognostic (1.54e-1)" "unprognostic (8.41e-2)" "unprognostic (1.27e-1)" "unprognostic (4.16e-1)" "unprognostic (2.25e-3)" "unprognostic (7.72e-2)" "unprognostic (2.32e-2)" "unprognostic (2.12e-3)" "unprognostic (6.27e-2)" "unprognostic (3.34e-4)" "unprognostic (2.58e-1)" "unprognostic (3.36e-4)" "unprognostic (1.23e-1)" "unprognostic (6.45e-2)" "unprognostic (7.59e-3)" "unprognostic (1.97e-1)" GUCA1A "C6orf131, COD3, CORD14, dJ139D8.6, GCAP, GCAP1, GUCA, GUCA1" ENSG00000048545 "Guanylate cyclase activator 1A" P43080 6 42173364-42181338 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 87 "retina: 734.2" "Group enriched" "Detected in some" 21 "Cone photoreceptor cells: 76.5;Rod photoreceptor cells: 83.6" "Cancer enriched" "Detected in single" 9 "testis cancer: 3.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "plasmacytoid DC: 4.9" "Lineage enriched" "Detected in single" 7 "dendritic cells: 4.9" "Cancer enhanced" "Detected in some" "Brain cancer: 1.7;lymphoma: 1.2;Neuroblastoma: 1.7" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA005561, HPA075056" Supported Approved "Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 7 "Plasma membrane" "HPA005561: AB_2667361, HPA075056: " "unprognostic (1.91e-2)" "unprognostic (3.92e-3)" "unprognostic (2.49e-2)" "unprognostic (9.16e-2)" "unprognostic (1.04e-4)" "unprognostic (9.70e-2)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (3.08e-3)" "unprognostic (2.79e-1)" "unprognostic (1.51e-1)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" GUCA1B "GCAP2, RP48" ENSG00000112599 "Guanylate cyclase activator 1B" Q9UMX6 6 42183284-42194956 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 102 "retina: 451.8" "Cell type enriched" "Detected in many" 4 "Cone photoreceptor cells: 2227.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA055479 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "HPA055479: AB_2732598" "unprognostic (1.61e-1)" "unprognostic (3.28e-1)" "unprognostic (1.14e-6)" "unprognostic (5.39e-2)" "unprognostic (1.73e-2)" "unprognostic (2.87e-3)" "unprognostic (6.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.34e-1)" "unprognostic (5.57e-1)" "unprognostic (1.66e-1)" "unprognostic (1.72e-2)" "unprognostic (3.28e-7)" "unprognostic (4.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.76e-2)" "unprognostic (2.59e-3)" HARS1 "HARS, HisRS, USH3B" ENSG00000170445 "Histidyl-tRNA synthetase 1" P12081 5 140673035-140691537 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036539 Approved Enhanced Cytosol NA NA 190000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Basal prostatic cells - Lipid metabolism" 1 Cytosol "HPA036539: AB_10669796" "unprognostic (9.35e-2)" "unprognostic (9.95e-2)" "unprognostic (1.62e-3)" "unprognostic (1.65e-2)" "unprognostic (2.33e-1)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.96e-7)" "unprognostic (6.50e-2)" "unprognostic (1.46e-1)" "unprognostic (3.82e-2)" "unprognostic (1.28e-2)" "unprognostic (2.40e-1)" "unprognostic (3.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.25e-1)" "unprognostic (6.26e-2)" "unprognostic (1.36e-1)" HGSNAT "FLJ32731, HGNAT, TMEM76" ENSG00000165102 "Heparan-alpha-glucosaminide N-acetyltransferase" Q68CP4 8 43140464-43202855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mucopolysaccharidosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029578 Approved NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" "HPA029578: AB_10602423" "unprognostic (5.35e-2)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.46e-4)" "unprognostic (3.94e-3)" "unprognostic (1.10e-1)" "unprognostic (6.54e-3)" "unprognostic (5.02e-2)" "prognostic favorable (6.33e-5)" "unprognostic (2.55e-2)" "unprognostic (5.48e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "unprognostic (3.45e-2)" HK1 ENSG00000156515 "Hexokinase 1" P19367 10 69269984-69401884 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycolysis, Immunity, Inflammatory response, Innate immunity" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Intellectual disability, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 276.7;Late spermatids: 976.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007043, HPA007044, CAB010052" Supported Supported Mitochondria NA NA 560000 "Cluster 40: Monocytes - Innate immune response" "Cluster 3: Non-specific - Unknown function" "Cluster 1: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 36: Late spermatids - Unknown function" 3 Mitochondria "CAB010052: AB_627721, HPA007043: AB_1850652, HPA007044: AB_1079049" "unprognostic (8.80e-2)" "unprognostic (1.78e-1)" "unprognostic (2.03e-1)" "unprognostic (2.00e-3)" "unprognostic (1.15e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (1.23e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (1.16e-1)" "unprognostic (3.93e-3)" "unprognostic (1.12e-1)" "unprognostic (1.37e-3)" "unprognostic (7.25e-2)" "unprognostic (1.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.86e-2)" HMCN1 "ARMD1, FBLN6, FIBL-6, FIBL6" ENSG00000143341 "Hemicentin 1" Q96RW7 1 185734391-186190949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Cell division, Sensory transduction, Vision" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.7" "Cell type enhanced" "Detected in many" "Adipocytes: 37.7;Endothelial cells: 22.1;Fibroblasts: 22.5;Lymphatic endothelial cells: 35.5;Microglial cells: 42.9;Oocytes: 16.9;Salivary duct cells: 17.1;Schwann cells: 22.2" "Cancer enriched" "Detected in many" 6 "melanoma: 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 64.8;skin cancer: 50.9" "Breast - Fibroblasts, Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Fibroblasts" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 13.2" "HPA008220, HPA051677" Uncertain Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" Other NA NA 9200000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 53: Fibroblasts - ECM organization" 1 "Golgi apparatus, Cytosol" "HPA008220: , HPA051677: AB_2681572" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (8.00e-2)" "unprognostic (1.10e-1)" "unprognostic (7.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.96e-1)" "unprognostic (4.36e-2)" "unprognostic (2.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.59e-7)" "unprognostic (1.22e-2)" "unprognostic (5.17e-3)" "unprognostic (3.52e-1)" "unprognostic (2.00e-3)" HSF4 CTM ENSG00000102878 "Heat shock transcription factor 4" Q9ULV5 16 67164681-67169945 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 36.5;Excitatory neurons: 29.9;Horizontal cells: 38.4;Inhibitory neurons: 28.8;Leydig cells: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048584 Supported "Nuclear speckles" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "Nuclear speckles" "HPA048584: AB_2680452" "unprognostic (1.90e-1)" "unprognostic (3.05e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (9.20e-3)" "unprognostic (2.61e-1)" "unprognostic (1.43e-1)" "unprognostic (8.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.06e-2)" "unprognostic (2.45e-1)" "unprognostic (2.85e-2)" "unprognostic (4.26e-3)" "prognostic unfavorable (2.19e-6)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (4.48e-2)" "unprognostic (8.74e-3)" HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 771.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 237.9;Mesothelial cells: 419.8;Muller glia cells: 335.4;Ovarian stromal cells: 227.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Kidney - Podocytes, Lung - Fibroblast_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Skin - Fibroblast_2, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" Enzyme NA NA 24800000 7600000 "Cluster 64: Neuronal - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 2 "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" IDH3A ENSG00000166411 "Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha" P50213 15 78131498-78171945 "Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 95.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 144.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041465, HPA062971" Supported Enhanced Mitochondria No No 110000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 35: Non-specific - Mitochondria" "Cluster 23: Choroid plexus - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 8: Neurons - Neuronal signaling" 2 Mitochondria "HPA041465: AB_10794377, HPA062971: AB_2684913" "unprognostic (2.33e-1)" "unprognostic (1.21e-1)" "unprognostic (5.76e-3)" "unprognostic (2.26e-1)" "unprognostic (1.02e-1)" "unprognostic (4.01e-1)" "unprognostic (2.29e-1)" "unprognostic (6.47e-2)" "unprognostic (1.69e-2)" "unprognostic (2.30e-1)" "unprognostic (3.05e-1)" "unprognostic (1.42e-1)" "prognostic favorable (6.49e-8)" "unprognostic (1.40e-1)" "unprognostic (3.08e-2)" "unprognostic (4.49e-2)" "unprognostic (3.39e-2)" IDH3B RP46 ENSG00000101365 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta" O43837 20 2658395-2664219 "Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 239.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049387, HPA054180" Supported Enhanced Mitochondria NA NA 8300 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA049387: AB_2680740, HPA054180: AB_2682407" "unprognostic (1.19e-1)" "unprognostic (1.47e-1)" "unprognostic (2.12e-1)" "unprognostic (2.43e-2)" "unprognostic (3.24e-2)" "unprognostic (6.83e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.76e-2)" "unprognostic (2.99e-1)" "unprognostic (5.69e-2)" "unprognostic (4.75e-3)" "unprognostic (1.39e-2)" "prognostic favorable (6.78e-8)" "unprognostic (8.89e-2)" "unprognostic (4.02e-2)" "unprognostic (2.79e-1)" "unprognostic (1.16e-1)" IFT140 "gs114, KIAA0590, WDTC2" ENSG00000187535 "Intraflagellar transport 140" Q96RY7 16 1510427-1612072 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 35.9;Late spermatids: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042197 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" 10 "HPA042197: AB_2677895" "unprognostic (1.53e-1)" "unprognostic (1.53e-1)" "unprognostic (1.30e-1)" "unprognostic (5.21e-3)" "unprognostic (2.27e-1)" "unprognostic (2.87e-2)" "unprognostic (5.27e-3)" "unprognostic (3.28e-2)" "unprognostic (2.63e-1)" "unprognostic (4.35e-3)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (2.77e-2)" "unprognostic (7.55e-2)" "unprognostic (8.95e-2)" "unprognostic (2.91e-3)" "unprognostic (6.22e-3)" IFT172 "BBS20, NPHP17, osm-1, SLB, wim" ENSG00000138002 "Intraflagellar transport 172" Q9UG01 2 27444377-27489805 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 310.3;Late spermatids: 759.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044893 Uncertain NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 3: Choroid plexus - Cilium" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 11: Late spermatids - Unknown function" 16 "HPA044893: AB_10795009" "unprognostic (1.05e-3)" "unprognostic (6.52e-2)" "unprognostic (7.04e-2)" "unprognostic (3.57e-3)" "unprognostic (1.95e-1)" "unprognostic (1.29e-2)" "prognostic unfavorable (6.05e-6)" "unprognostic (6.86e-3)" "unprognostic (1.45e-1)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (1.51e-2)" "unprognostic (4.32e-2)" "unprognostic (9.52e-2)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (5.47e-2)" IFT43 "C14orf179, FLJ32173, MGC16028" ENSG00000119650 "Intraflagellar transport 43" Q96FT9 14 75902136-76084585 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ciliated cells: 227.2;Early spermatids: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003438 Approved Supported "Microtubules,Centriolar satellite" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 42: Ciliated cells - Cilium assembly" 8 Microtubules "Centriolar satellite" "HPA003438: AB_1078327" "unprognostic (1.64e-2)" "unprognostic (5.75e-3)" "unprognostic (2.10e-1)" "unprognostic (1.81e-3)" "unprognostic (1.48e-1)" "unprognostic (8.73e-2)" "unprognostic (1.53e-2)" "unprognostic (5.27e-2)" "unprognostic (8.87e-2)" "unprognostic (1.26e-2)" "unprognostic (2.32e-2)" "unprognostic (9.78e-2)" "unprognostic (4.43e-2)" "unprognostic (2.51e-1)" "unprognostic (2.70e-2)" "unprognostic (1.75e-1)" "unprognostic (1.07e-2)" IMPDH1 "LCA11, RP10, sWSS2608" ENSG00000106348 "Inosine monophosphate dehydrogenase 1" P20839 7 128392277-128410252 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" "DNA-binding, Oxidoreductase, RNA-binding" "Disease variant, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 102.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 166.2;Cone photoreceptor cells: 175.0;Rod photoreceptor cells: 186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 89.2;eosinophil: 89.3;intermediate monocyte: 104.6;myeloid DC: 60.0;neutrophil: 198.3;non-classical monocyte: 136.7" "Group enriched" "Detected in all" 5 "dendritic cells: 60.0;granulocytes: 198.3;monocytes: 136.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001400 Approved Supported "Cytosol,Rods & Rings" NA NA 17000 "Cluster 7: Non-specific - Innate immune response" "Cluster 76: Retina - Visual perception" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 66: Photoreceptor cells - Visual perception" Cytosol "Rods & Rings" "HPA001400: AB_1079139" "unprognostic (2.84e-1)" "prognostic unfavorable (3.87e-4)" "unprognostic (2.23e-2)" "unprognostic (6.45e-2)" "prognostic unfavorable (7.31e-5)" "unprognostic (6.03e-2)" "prognostic unfavorable (1.12e-7)" "unprognostic (1.24e-1)" "unprognostic (7.45e-3)" "unprognostic (1.03e-2)" "unprognostic (1.79e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.78e-12)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.72e-5)" IMPG1 "GP147, IPM150, SPACR" ENSG00000112706 "Interphotoreceptor matrix proteoglycan 1" Q17R60 6 75921114-76072678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 99 "retina: 650.2" "Group enriched" "Detected in some" 5 "Cone photoreceptor cells: 863.2;Rod photoreceptor cells: 635.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 2.0" "Region enriched" "Detected in single" 4 "basal ganglia: 3.3" "Low region specificity" "Detected in many" "HPA027142, HPA030332, HPA030333" Enhanced "Secreted in other tissues" Receptor NA NA "Cluster 76: Retina - Visual perception" "Cluster 34: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA027142: AB_2672132, HPA030332: AB_2673432, HPA030333: AB_2673433" "unprognostic (6.65e-2)" "unprognostic (4.13e-2)" "unprognostic (1.20e-1)" "unprognostic (8.69e-2)" "unprognostic (1.22e-1)" "unprognostic (5.49e-3)" "unprognostic (5.97e-2)" "unprognostic (3.56e-3)" "unprognostic (1.89e-2)" "unprognostic (2.20e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-3)" "unprognostic (2.84e-1)" "unprognostic (1.73e-2)" "unprognostic (2.09e-1)" "unprognostic (6.01e-2)" "unprognostic (1.96e-2)" IMPG2 "IPM200, RP56, SPACRCAN" ENSG00000081148 "Interphotoreceptor matrix proteoglycan 2" Q9BZV3 3 101222546-101320575 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Heparin-binding, Receptor" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "retina: 296.1" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 640.6;Rod photoreceptor cells: 334.9" "Cancer enriched" "Detected in single" 12 "ovarian cancer: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Brain cancer: 2.3;lung cancer: 1.2;ovarian cancer: 2.2;Uterine cancer: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008779, HPA015907" Enhanced "Secreted in other tissues" Receptor NA NA "Cluster 76: Retina - Visual perception" "Cluster 44: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA008779: AB_2668138, HPA015907: AB_2669323" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.40e-1)" "unprognostic (9.58e-3)" "unprognostic (1.28e-1)" "unprognostic (4.80e-5)" "unprognostic (6.66e-4)" "unprognostic (1.85e-1)" "unprognostic (1.09e-1)" "unprognostic (6.59e-2)" "unprognostic (7.51e-3)" "unprognostic (1.28e-1)" "unprognostic (4.50e-9)" "unprognostic (7.12e-2)" "unprognostic (2.70e-1)" "unprognostic (2.81e-2)" "unprognostic (6.08e-2)" KCNJ13 "Kir1.4, Kir7.1, LCA16" ENSG00000115474 "Potassium inwardly rectifying channel subfamily J member 13" O60928 2 232765802-232776565 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cataract, Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 170.7;intestine: 88.7" "Cell type enhanced" "Detected in some" "Melanocytes: 29.2;Muller glia cells: 52.0;Proximal enterocytes: 219.0;Undifferentiated cells: 65.7" "Cancer enriched" "Detected in some" 5 "melanoma: 5.9" "Region enriched" "Detected in all" 15 "choroid plexus: 342.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.1" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051609 Approved "Nuclear membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Proximal enterocytes - Digestion" "Nuclear membrane" "HPA051609: " "unprognostic (4.29e-2)" "unprognostic (2.00e-1)" "unprognostic (2.69e-1)" "unprognostic (9.03e-5)" "unprognostic (1.17e-1)" "unprognostic (3.12e-2)" "unprognostic (2.26e-1)" "unprognostic (3.44e-2)" "unprognostic (1.40e-1)" "unprognostic (1.41e-1)" "unprognostic (4.90e-2)" "unprognostic (1.86e-2)" "unprognostic (2.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.82e-2)" "unprognostic (1.11e-2)" KCNV2 Kv8.2 ENSG00000168263 "Potassium voltage-gated channel modifier subfamily V member 2" Q8TDN2 9 2717510-2730037 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "retina: 280.3" "Group enriched" "Detected in some" 10 "Cone photoreceptor cells: 1522.4;Rod photoreceptor cells: 472.1" "Cancer enriched" "Detected in single" 78 "testis cancer: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA031131 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 1 "HPA031131: AB_10609996" "unprognostic (5.06e-2)" "unprognostic (1.47e-3)" "unprognostic (3.45e-3)" "unprognostic (6.41e-2)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "unprognostic (1.12e-3)" "unprognostic (5.38e-2)" "unprognostic (1.39e-2)" "unprognostic (1.69e-1)" "unprognostic (5.21e-2)" "unprognostic (2.35e-1)" "unprognostic (7.96e-8)" "unprognostic (3.01e-1)" "unprognostic (4.90e-2)" "unprognostic (9.90e-2)" "unprognostic (1.06e-2)" KIAA1549 ENSG00000122778 KIAA1549 Q9HCM3 7 138831381-138981389 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 49.8;Excitatory neurons: 89.1;granulocytes: 90.9;Inhibitory neurons: 52.3;Oligodendrocyte precursor cells: 65.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 20.4" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019560 Uncertain Approved "Nuclear membrane,Intermediate filaments" NA NA 14000 "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 30: Granulocytes - Unknown function" "Nuclear membrane" "Intermediate filaments" "HPA019560: AB_1852418" "unprognostic (7.88e-2)" "unprognostic (2.37e-2)" "unprognostic (2.63e-1)" "unprognostic (6.85e-2)" "unprognostic (2.29e-1)" "unprognostic (8.86e-2)" "unprognostic (2.55e-2)" "unprognostic (6.40e-2)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (2.33e-2)" "unprognostic (8.30e-2)" "prognostic favorable (3.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "unprognostic (2.38e-1)" "unprognostic (1.28e-2)" KIF21A "FEOM1, FLJ20052" ENSG00000139116 "Kinesin family member 21A" Q7Z4S6 12 39293228-39443390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 75.2" "Cell type enhanced" "Detected in all" "Bipolar cells: 276.1;Cone photoreceptor cells: 268.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 7.1;MAIT T-cell: 3.4;memory CD4 T-cell: 4.4;memory CD8 T-cell: 7.3;naive CD8 T-cell: 4.8;NK-cell: 3.0;T-reg: 2.2" "Group enriched" "Detected in many" 9 "NK-cells: 3.0;T-cells: 7.3" "Cancer enhanced" "Detected in all" "Neuroblastoma: 113.1" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022079, HPA058432" Enhanced Enhanced Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 45: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" 2 Cytosol "CAB022079: , HPA058432: AB_2683717" "unprognostic (1.08e-3)" "unprognostic (3.40e-1)" "unprognostic (2.06e-2)" "unprognostic (7.67e-2)" "unprognostic (1.13e-1)" "unprognostic (3.09e-1)" "unprognostic (2.24e-3)" "unprognostic (7.77e-2)" "unprognostic (3.17e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (1.73e-2)" "prognostic favorable (8.07e-8)" "unprognostic (4.05e-2)" "unprognostic (1.66e-1)" "unprognostic (2.14e-1)" "unprognostic (2.34e-2)" KIF3B "FLA8, KIAA0359, KLP-11" ENSG00000101350 "Kinesin family member 3B" O15066 20 32277651-32335011 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 89.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007119, HPA066525" Approved Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 62: Non-specific - Plasma proteins" "Cluster 42: Ciliated cells - Cilium assembly" 5 "Plasma membrane, Actin filaments" "HPA007119: AB_1852498, HPA066525: " "unprognostic (1.74e-2)" "unprognostic (2.25e-1)" "unprognostic (5.14e-2)" "unprognostic (1.84e-1)" "unprognostic (2.73e-1)" "unprognostic (2.89e-1)" "unprognostic (1.49e-2)" "unprognostic (2.14e-1)" "unprognostic (9.01e-3)" "unprognostic (9.30e-2)" "unprognostic (1.41e-1)" "unprognostic (1.18e-1)" "prognostic favorable (1.44e-12)" "unprognostic (2.41e-2)" "unprognostic (2.68e-1)" "unprognostic (5.11e-2)" "unprognostic (4.42e-2)" KLC2 FLJ12387 ENSG00000174996 "Kinesin light chain 2" Q9H0B6 11 66257294-66267860 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 48.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040416, HPA040434" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 20: Enteroendocrine cells - Hormone signaling" 4 "Plasma membrane, Cytosol" "Nucleoplasm, Mitochondria" "HPA040416: AB_10795524, HPA040434: AB_10795367" "unprognostic (1.29e-1)" "unprognostic (4.95e-3)" "unprognostic (2.99e-1)" "unprognostic (3.24e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" "unprognostic (6.27e-3)" "unprognostic (1.60e-1)" "unprognostic (3.49e-2)" "unprognostic (1.64e-3)" "unprognostic (4.57e-3)" "unprognostic (1.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.72e-2)" "unprognostic (8.08e-2)" KLHL7 "KLHL6, RP42, SBBI26" ENSG00000122550 "Kelch like family member 7" Q8IXQ5 7 23105758-23177914 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 49.0" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 144.1;Early spermatids: 564.0;Late spermatids: 322.5;Oligodendrocyte precursor cells: 158.5;Oocytes: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029491, HPA029492" Uncertain Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 44: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 67: Non-specific - Unknown function" "Cluster 21: Early spermatids - Spermatogenesis" 1 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029491: AB_10599605, HPA029492: AB_10600881" "unprognostic (1.24e-2)" "unprognostic (4.45e-1)" "unprognostic (1.77e-1)" "unprognostic (4.55e-2)" "unprognostic (1.29e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (3.78e-1)" "unprognostic (6.10e-2)" "unprognostic (6.41e-3)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "prognostic favorable (8.98e-5)" "unprognostic (2.46e-2)" "unprognostic (3.55e-3)" "unprognostic (3.23e-2)" "unprognostic (2.27e-2)" KRT12 K12 ENSG00000187242 "Keratin 12" Q99456 17 40861303-40867223 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Corneal dystrophy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal enterocytes: 5.4;Intestinal goblet cells: 1.5;Late spermatids: 1.8;Paneth cells: 8.5;Proximal enterocytes: 1.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.0" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055217, HPA055835" Enhanced NA NA "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 5: Enterocytes - Absorption" "HPA055217: AB_2682742, HPA055835: AB_2682935" "unprognostic (1.89e-1)" "unprognostic (2.40e-2)" "unprognostic (1.01e-1)" "unprognostic (4.82e-1)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.74e-2)" "unprognostic (5.52e-2)" "unprognostic (9.41e-3)" "unprognostic (3.49e-1)" "unprognostic (1.73e-1)" "unprognostic (3.94e-3)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "unprognostic (2.60e-4)" "unprognostic (6.31e-3)" LCA5 C6orf152 ENSG00000135338 "Lebercilin LCA5" Q86VQ0 6 79484991-79537458 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 71.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029053, HPA029054, HPA029055" Supported Approved "Centriolar satellite" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 17: Choroid plexus - Cilium" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Ciliated cells - Cilium assembly" 9 "Centriolar satellite" "HPA029053: AB_10602020, HPA029054: , HPA029055: AB_2672889" "unprognostic (8.96e-2)" "unprognostic (1.04e-1)" "unprognostic (3.06e-2)" "unprognostic (2.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (6.58e-2)" "unprognostic (1.34e-3)" "unprognostic (6.83e-2)" "unprognostic (2.73e-2)" "unprognostic (4.11e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (7.09e-3)" "unprognostic (1.39e-1)" "unprognostic (5.39e-2)" "unprognostic (3.21e-2)" LEMD2 "dJ482C21.1, LEM2, NET25" ENSG00000161904 "LEM domain nuclear envelope protein 2" Q8NC56 6 33771202-33789130 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017340 Supported Supported "Nuclear membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 28: Non-specific - Nuclear processes" "Cluster 63: Late spermatids - Spermatogenesis" "Nuclear membrane" "HPA017340: AB_2296925" "unprognostic (9.01e-2)" "unprognostic (7.99e-2)" "unprognostic (1.18e-1)" "unprognostic (4.12e-2)" "unprognostic (2.98e-1)" "unprognostic (8.29e-3)" "unprognostic (6.53e-2)" "unprognostic (5.98e-2)" "unprognostic (4.42e-2)" "unprognostic (7.03e-2)" "unprognostic (1.67e-3)" "unprognostic (2.11e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (2.43e-1)" "unprognostic (7.54e-2)" "unprognostic (3.82e-2)" "unprognostic (7.12e-2)" LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753120 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 2.1" "Cell type enhanced" "Detected in many" "Early spermatids: 22.5;Granulosa cells: 31.5;Schwann cells: 48.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Colon - Enteric glia cells, Lung - Alveolar cells type 2, Skin - Outer root sheath cells, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA070726 Uncertain "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 3 "Golgi apparatus" "Endoplasmic reticulum" "HPA070726: " "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (4.75e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.65e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-4)" "unprognostic (4.49e-6)" "unprognostic (6.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" LRIT3 "CSNB1F, FIGLER4, FLJ44691" ENSG00000183423 "Leucine rich repeat, Ig-like and transmembrane domains 3" Q3SXY7 4 109848107-109872315 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "retina: 17.0" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 20.4;Muller glia cells: 8.1;Rod photoreceptor cells: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013454 Enhanced Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" "Nucleoplasm, Mitochondria, Cytosol" "HPA013454: AB_1853277" "unprognostic (5.41e-2)" "unprognostic (6.82e-2)" "unprognostic (4.20e-2)" "unprognostic (6.50e-2)" "unprognostic (3.42e-1)" "unprognostic (7.67e-3)" "unprognostic (1.54e-1)" "unprognostic (5.25e-2)" "unprognostic (3.16e-2)" "unprognostic (4.49e-2)" "unprognostic (6.92e-3)" "unprognostic (3.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (1.14e-2)" LRP5 "BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2" ENSG00000162337 "LDL receptor related protein 5" O75197 11 68312591-68449275 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Wnt signaling pathway" "Developmental protein, Receptor" "Disease variant, Osteogenesis imperfecta, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 126.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 91.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013001, HPA030505" Enhanced NA NA 1500000 "Cluster 83: Liver - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 75: Serous glandular cells - Salivary secretion" 3 "CAB013001: AB_2533267, HPA030505: AB_2673505" "unprognostic (3.67e-1)" "unprognostic (2.98e-2)" "unprognostic (1.11e-1)" "unprognostic (3.13e-2)" "unprognostic (3.33e-1)" "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (2.94e-2)" "unprognostic (9.63e-2)" "unprognostic (2.54e-1)" "unprognostic (2.78e-1)" "unprognostic (6.82e-2)" "prognostic favorable (3.55e-10)" "unprognostic (2.28e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (7.42e-2)" LRPAP1 "A2MRAP, HBP44, RAP" ENSG00000163956 "LDL receptor related protein associated protein 1" P30533 4 3503612-3532446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 598.2;Syncytiotrophoblasts: 752.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008001, CAB025518, HPA073239" Enhanced Supported Enhanced "Endoplasmic reticulum" NA NA 810000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Cytotrophoblasts - Mitochondria" 6 "Endoplasmic reticulum" "CAB025518: , HPA008001: AB_1853292, HPA073239: " "unprognostic (3.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.30e-1)" "unprognostic (2.22e-2)" "unprognostic (1.37e-2)" "unprognostic (9.61e-2)" "unprognostic (1.01e-2)" "unprognostic (3.89e-3)" "unprognostic (8.58e-2)" "unprognostic (6.12e-2)" "unprognostic (2.14e-3)" "unprognostic (2.19e-1)" "prognostic favorable (4.67e-11)" "unprognostic (6.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.58e-1)" "unprognostic (5.61e-2)" LSS OSC ENSG00000160285 "Lanosterol synthase" P48449 21 46188141-46228824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Isomerase "Cataract, Disease variant, Hypotrichosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 127.6;Oligodendrocytes: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032060, HPA032062, CAB034116" Supported NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 62: Hepatocytes - Metabolism" 7 "CAB034116: AB_2138611, HPA032060: AB_10671085, HPA032062: AB_2674134" "unprognostic (2.78e-3)" "unprognostic (8.53e-3)" "unprognostic (6.95e-2)" "unprognostic (2.07e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (2.74e-2)" "unprognostic (1.33e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-2)" "unprognostic (1.68e-2)" "unprognostic (2.02e-2)" "unprognostic (2.34e-2)" "prognostic unfavorable (6.80e-4)" "unprognostic (1.92e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.07e-4)" MAF c-MAF ENSG00000178573 "MAF bZIP transcription factor" O75444 16 79585843-79600737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Intellectual disability, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 255.8;Inhibitory neurons: 363.0;Kupffer cells: 382.8;Lymphatic endothelial cells: 281.1;Proximal enterocytes: 279.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 38.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 38.1" "Cancer enriched" "Detected in many" 7 "Myeloma: 58.6" "Breast - Fibroblasts, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010296, HPA028289" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "Nucleoplasm, Nuclear bodies" Vesicles "CAB010296: AB_638562, HPA028289: AB_10602024" "unprognostic (6.76e-2)" "unprognostic (1.74e-2)" "unprognostic (6.45e-2)" "unprognostic (7.65e-2)" "unprognostic (7.89e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (2.33e-1)" "unprognostic (8.76e-2)" "unprognostic (3.16e-2)" "unprognostic (9.46e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.74e-4)" "unprognostic (4.54e-2)" "unprognostic (7.83e-2)" "unprognostic (1.09e-2)" "unprognostic (4.56e-3)" MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 264.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 399.9;Kupffer cells: 528.6;Macrophages: 538.4;monocytes: 1168.6;Squamous epithelial cells: 370.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.9" "Lineage enriched" "Detected in many" 15 "monocytes: 121.9" "Cancer enhanced" "Detected in many" "Bone cancer: 29.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Fibroblasts, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Podocytes, Lung - Macrophages, Prostate - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 40: Monocytes - Innate immune response" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 58: Macrophages - Innate immune response" 5 Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: AB_1079293" "unprognostic (1.55e-1)" "unprognostic (1.17e-2)" "unprognostic (1.16e-3)" "prognostic unfavorable (5.64e-4)" "unprognostic (9.16e-2)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-1)" "unprognostic (2.57e-2)" "unprognostic (6.09e-2)" "unprognostic (5.45e-3)" "unprognostic (9.92e-2)" "unprognostic (3.95e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-3)" "unprognostic (3.49e-2)" "unprognostic (2.30e-2)" MAPKAPK3 "3pK, MAPKAP3, MK-3, MK3" ENSG00000114738 "MAPK activated protein kinase 3" Q16644 3 50611520-50649291 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 105.2;heart muscle: 248.1;skeletal muscle: 216.2;tongue: 273.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 233.9;Hofbauer cells: 112.4;monocytes: 201.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 142.9;granulocytes: 126.6;monocytes: 343.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058275 Supported Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 3 Nucleoplasm "HPA058275: AB_2683663" "unprognostic (6.46e-3)" "unprognostic (1.84e-1)" "prognostic favorable (8.08e-5)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (9.96e-2)" "unprognostic (8.77e-3)" "unprognostic (7.68e-3)" "unprognostic (1.11e-1)" "unprognostic (5.87e-2)" "unprognostic (2.19e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.90e-8)" "unprognostic (2.15e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898607-112029561 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 92.5" "Cell type enhanced" "Detected in many" "Astrocytes: 154.2;Kupffer cells: 106.1;Macrophages: 62.0;Microglial cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "intermediate monocyte: 8.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 50 "monocytes: 8.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" Yes NA 65000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: AB_2686759" "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favorable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" MIP "AQP0, LIM1, MP26" ENSG00000135517 "Major intrinsic protein of lens fiber" P30301 12 56449502-56469166 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Transport, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA014940 Supported NA NA "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Non-specific - Transcription" 35 "HPA014940: AB_2669122" "unprognostic (6.48e-2)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (7.14e-2)" "unprognostic (3.96e-2)" "unprognostic (2.90e-3)" "unprognostic (1.72e-1)" "unprognostic (3.47e-1)" "unprognostic (1.51e-5)" "unprognostic (4.56e-3)" "unprognostic (6.75e-2)" "unprognostic (1.16e-2)" "unprognostic (2.83e-2)" "unprognostic (3.27e-1)" "unprognostic (2.62e-1)" "unprognostic (8.82e-2)" MYO7A "DFNA11, DFNB2, NSRD2, USH1B" ENSG00000137474 "Myosin VIIA" Q13402 11 77128246-77215241 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Deafness, Disease variant, Leber congenital amaurosis, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 40.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 17.4;Cone photoreceptor cells: 22.1;Cytotrophoblasts: 43.2;Hofbauer cells: 25.6;Kupffer cells: 17.1;Muller glia cells: 15.3;Rod photoreceptor cells: 33.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 108.5" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.6;intermediate monocyte: 1.7" "Lineage enriched" "Detected in single" 4 "monocytes: 2.6" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Kidney - Proximal tubular cells, Skeletal muscle - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB034059 Uncertain NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 24: Cytotrophoblasts - Mitochondria" "CAB034059: AB_2148626" "unprognostic (1.14e-3)" "unprognostic (2.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.61e-1)" "unprognostic (9.66e-2)" "unprognostic (4.02e-3)" "unprognostic (1.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-1)" "unprognostic (1.32e-1)" "unprognostic (3.65e-2)" "unprognostic (6.81e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.31e-1)" "unprognostic (1.14e-1)" "unprognostic (1.10e-2)" "unprognostic (3.03e-2)" MYOC "GLC1A, JOAG1, TIGR" ENSG00000034971 Myocilin Q99972 1 171635417-171652688 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 106.5" "Cell type enriched" "Detected in some" 4 "Fibroblasts: 184.6" "Cancer enriched" "Detected in many" 6 "melanoma: 13.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 45 "Rhabdoid: 209.3" "Colon - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA027364 Uncertain "Secreted to extracellular matrix" "No annotated function" NA NA 25000000 "Cluster 35: Non-specific - Mitochondria" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 4 "HPA027364: AB_10602036" "unprognostic (2.02e-2)" "unprognostic (4.65e-2)" "unprognostic (4.44e-2)" "unprognostic (6.29e-2)" "unprognostic (1.43e-1)" "unprognostic (2.33e-2)" "unprognostic (3.42e-2)" "unprognostic (3.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.54e-1)" "unprognostic (1.94e-4)" "unprognostic (5.35e-2)" "unprognostic (1.87e-1)" "unprognostic (3.87e-2)" "unprognostic (1.24e-1)" NDP "EVR2, norrin" ENSG00000124479 "Norrin cystine knot growth factor NDP" Q00604 X 43948776-43973395 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision, Wnt signaling pathway" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.8;ovary: 32.8" "Cell type enhanced" "Detected in some" "Astrocytes: 27.6;Granulosa cells: 78.9;Muller glia cells: 105.8;Ovarian stromal cells: 55.4" "Cancer enriched" "Detected in many" 5 "glioma: 25.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Brain cancer: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003095 Supported Nucleoplasm,Nucleoli,Vesicles "Secreted to extracellular matrix" Other NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Ovarian stromal cells - Transcription" 1 Vesicles "Nucleoplasm, Nucleoli" "HPA003095: AB_1079457" "unprognostic (1.12e-1)" "unprognostic (7.12e-2)" "unprognostic (2.27e-2)" "unprognostic (2.55e-3)" "unprognostic (6.84e-3)" "unprognostic (1.51e-1)" "unprognostic (9.09e-2)" "unprognostic (2.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 17.5;lymphoid tissue: 18.7;testis: 65.2" "Cell type enhanced" "Detected in many" "Early spermatids: 83.0;Erythroid cells: 42.1;Late spermatids: 38.7;Spermatocytes: 210.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid - Mitotic cells (Thyroid)" "Region enhanced" "Detected in many" "cerebellum: 5.7" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 4: Testis - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 4 "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: AB_2685393" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (9.47e-6)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" NHS ENSG00000188158 "NHS actin remodeling regulator" Q6T4R5 X 17375200-17735994 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Inhibitory neurons: 253.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA031497, HPA076257" Uncertain Supported "Cell Junctions" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 8: Neurons - Neuronal signaling" "Cell Junctions" "HPA031497: AB_10610144, HPA076257: AB_2686789" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (1.17e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.58e-1)" "unprognostic (1.69e-1)" "unprognostic (9.92e-3)" "unprognostic (3.27e-3)" "unprognostic (1.08e-1)" "unprognostic (1.78e-1)" "unprognostic (1.61e-3)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-2)" "unprognostic (1.21e-1)" "unprognostic (8.83e-3)" "unprognostic (1.83e-3)" NMNAT1 "LCA9, NMNAT, PNAT1" ENSG00000173614 "Nicotinamide nucleotide adenylyltransferase 1" Q9HAN9 1 9943428-9985501 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Deafness, Disease variant, Dwarfism, Intellectual disability, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059447 Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 8: Neurons - Neuronal signaling" 11 "Nucleoplasm, Nuclear bodies" "HPA059447: AB_2684022" "unprognostic (1.94e-1)" "unprognostic (3.81e-3)" "unprognostic (7.54e-3)" "unprognostic (1.01e-1)" "unprognostic (3.50e-1)" "unprognostic (1.73e-1)" "unprognostic (1.56e-1)" "unprognostic (2.29e-1)" "unprognostic (4.45e-3)" "unprognostic (4.55e-2)" "unprognostic (1.12e-1)" "unprognostic (3.57e-1)" "prognostic favorable (3.85e-14)" "unprognostic (3.11e-3)" "unprognostic (1.17e-1)" "unprognostic (1.47e-3)" "unprognostic (5.16e-2)" NR2F1 "COUP-TFI, COUPTF1, EAR-3, ERBAL3, SVP44, TCFCOUP1, TFCOUP1" ENSG00000175745 "Nuclear receptor subfamily 2 group F member 1" P10589 5 93583222-93594611 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 324.1;Fibroblasts: 129.8;Lymphatic endothelial cells: 450.2;Mesothelial cells: 171.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 121.0" "Adipose visceral - Mesothelial cells, Kidney - Fibroblasts, Lung - Fibroblast_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019281, HPA058974" Approved Nucleoplasm,Cytosol NA NA "Cluster 64: Neuronal - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" 1 Nucleoplasm Cytosol "CAB019281: , HPA058974: AB_2732629" "unprognostic (8.07e-2)" "unprognostic (1.06e-2)" "unprognostic (3.86e-2)" "unprognostic (2.26e-1)" "unprognostic (4.75e-1)" "unprognostic (7.68e-3)" "unprognostic (3.18e-3)" "unprognostic (3.07e-2)" "unprognostic (2.21e-1)" "unprognostic (2.71e-3)" "unprognostic (5.24e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.32e-2)" "unprognostic (1.61e-1)" "unprognostic (9.28e-2)" "prognostic unfavorable (1.47e-4)" NRL "D14S46E, NRL-MAF, RP27" ENSG00000129535 "Neural retina leucine zipper" P54845 14 24078662-24115010 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 75 "retina: 307.1" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 3363.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Uterine cancer: 10.1" "Testis - Early spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB026066, HPA064599" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Retina - Visual perception" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" Nucleoplasm Cytosol "CAB026066: , HPA064599: AB_2685295" "unprognostic (2.71e-2)" "unprognostic (8.17e-4)" "unprognostic (4.60e-2)" "unprognostic (1.80e-1)" "unprognostic (7.23e-2)" "unprognostic (1.99e-2)" "unprognostic (5.29e-2)" "unprognostic (1.88e-5)" "unprognostic (3.59e-2)" "unprognostic (7.84e-3)" "unprognostic (1.75e-3)" "unprognostic (3.49e-2)" "unprognostic (2.38e-5)" "unprognostic (2.56e-2)" "unprognostic (1.10e-1)" "unprognostic (1.73e-1)" "unprognostic (1.35e-3)" NTF4 "GLC1O, NT-4/5, NTF5" ENSG00000225950 "Neurotrophin 4" P34130 19 49061066-49065076 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Glaucoma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 19.5;skeletal muscle: 13.9;skin 1: 15.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 6.7;Basal respiratory cells: 23.0;Breast myoepithelial cells: 27.7;Club cells: 8.2;Cytotrophoblasts: 13.6;Ionocytes: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.9" "Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049376 Approved "Golgi apparatus" "Secreted in other tissues" "Growth factor" NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 3 "Golgi apparatus" "HPA049376: AB_2680735" "unprognostic (4.15e-2)" "unprognostic (1.07e-1)" "unprognostic (9.27e-4)" "unprognostic (1.76e-4)" "unprognostic (2.36e-1)" "unprognostic (1.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.73e-2)" "unprognostic (4.87e-3)" "unprognostic (3.90e-4)" "unprognostic (2.97e-1)" "unprognostic (1.40e-3)" "unprognostic (3.71e-2)" "unprognostic (2.49e-1)" "unprognostic (1.89e-2)" "unprognostic (2.46e-3)" OFD1 "71-7A, CXorf5, JBTS10, RP23" ENSG00000046651 "OFD1 centriole and centriolar satellite protein" O75665 X 13734743-13777955 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 266.5;Oocytes: 288.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in all" 6 "plasmacytoid DC: 69.8" "Lineage enriched" "Detected in all" 6 "dendritic cells: 69.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031102, HPA031103, HPA031104" Approved Supported Microtubules NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Ribosome" "Cluster 44: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 37: Glandular & Luminal cells - Unknown function" 13 Microtubules "HPA031102: AB_10670836, HPA031103: AB_10602188, HPA031104: AB_10669655" "unprognostic (3.10e-3)" "prognostic favorable (9.62e-4)" "unprognostic (2.83e-1)" "unprognostic (2.68e-2)" "unprognostic (1.10e-1)" "unprognostic (7.42e-3)" "unprognostic (2.20e-3)" "unprognostic (3.03e-3)" "unprognostic (1.82e-2)" "unprognostic (1.43e-3)" "unprognostic (2.82e-1)" "unprognostic (1.50e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (3.32e-2)" "unprognostic (3.90e-2)" "unprognostic (1.04e-2)" "prognostic favorable (2.76e-7)" OPA1 "FLJ12460, KIAA0567, MGM1, NPG, NTG" ENSG00000198836 "OPA1 mitochondrial dynamin like GTPase" O60313 3 193593144-193697811 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Sensory transduction, Vision" Hydrolase "Cardiomyopathy, Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 216.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036926, HPA036927" Supported Supported Nucleoplasm,Mitochondria NA NA 10000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 35: Non-specific - Mitochondria" "Cluster 14: Neurons - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 68: Cardiomyocytes - Muscle contraction" 5 "Nucleoplasm, Mitochondria" "HPA036926: AB_10671247, HPA036927: AB_2675388" "unprognostic (2.10e-2)" "unprognostic (9.23e-3)" "unprognostic (7.98e-2)" "prognostic unfavorable (8.61e-4)" "unprognostic (1.62e-2)" "unprognostic (4.59e-2)" "unprognostic (2.24e-1)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (3.48e-2)" "prognostic favorable (1.84e-4)" "unprognostic (2.92e-1)" "unprognostic (4.75e-1)" "unprognostic (4.50e-3)" "unprognostic (3.21e-1)" OPA3 "FLJ22187, MGA3" ENSG00000125741 "Outer mitochondrial membrane lipid metabolism regulator OPA3" Q9H6K4 19 45527767-45602212 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044881 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mitochondria" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 48: Smooth muscle cells - Signal transduction" Cytosol Nucleoplasm "HPA044881: AB_10964052" "unprognostic (3.37e-1)" "unprognostic (3.89e-2)" "unprognostic (2.66e-1)" "unprognostic (5.71e-3)" "unprognostic (1.24e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (3.14e-3)" "unprognostic (4.53e-2)" "unprognostic (8.06e-3)" "unprognostic (1.72e-3)" "unprognostic (8.73e-2)" "prognostic favorable (9.30e-12)" "unprognostic (5.85e-2)" "unprognostic (1.94e-1)" "unprognostic (3.82e-2)" "unprognostic (1.81e-1)" OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 39.7" "Cell type enriched" "Detected in some" 20 "Cone photoreceptor cells: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 76: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 66: Photoreceptor cells - Visual perception" "Nucleoplasm, Cytosol" "Cytokinetic bridge" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" OPTN "FIP-2, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP" ENSG00000123240 Optineurin Q96CV9 10 13099449-13138308 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Immunity, Innate immunity" "Amyotrophic lateral sclerosis, Disease variant, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 848.4;tongue: 379.4" "Cell type enhanced" "Detected in all" "Late spermatids: 885.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003279, HPA003360, CAB019303" Approved Enhanced Cytosol NA NA 370000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 63: Late spermatids - Spermatogenesis" 127 Cytosol "CAB019303: , HPA003279: AB_1079527, HPA003360: AB_1079528" "unprognostic (2.84e-2)" "unprognostic (3.37e-1)" "unprognostic (3.79e-3)" "unprognostic (6.46e-3)" "unprognostic (5.58e-2)" "unprognostic (3.74e-2)" "unprognostic (5.15e-3)" "unprognostic (3.14e-2)" "unprognostic (2.68e-2)" "unprognostic (2.16e-1)" "unprognostic (1.40e-2)" "unprognostic (6.14e-1)" "prognostic unfavorable (5.81e-5)" "unprognostic (7.62e-2)" "unprognostic (5.67e-2)" "unprognostic (7.93e-2)" "unprognostic (2.09e-2)" OVOL2 "bA504H3.3, CHED, CHED1, HOVO2, ZNF339" ENSG00000125850 "Ovo like zinc finger 2" Q9BRP0 20 17956979-18059188 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Corneal dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 6.9;stomach 1: 7.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 24.3;Spermatocytes: 31.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Group enriched" "Detected in some" 5 "cerebral cortex: 5.3;hippocampal formation: 4.3" HPA038531 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 Nucleoplasm Cytosol "HPA038531: AB_10673012" "unprognostic (2.85e-2)" "unprognostic (5.13e-2)" "unprognostic (2.41e-2)" "unprognostic (7.35e-2)" "unprognostic (2.14e-1)" "unprognostic (5.14e-2)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.40e-1)" "unprognostic (2.61e-1)" "unprognostic (2.63e-2)" "unprognostic (1.62e-1)" "unprognostic (1.84e-4)" "unprognostic (4.77e-3)" "unprognostic (2.92e-1)" "unprognostic (2.57e-2)" "unprognostic (3.76e-2)" P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 72.1;Excitatory neurons: 53.7;Inhibitory neurons: 57.9;Microglial cells: 87.7;Prostatic glandular cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in single" 112 "dendritic cells: 28.9" "Cancer enhanced" "Detected in all" "Kidney cancer: 132.1" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 47: Spleen - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Vesicles, Cytosol" "HPA007890: AB_1852796, HPA013355: AB_1852798, HPA013611: " "unprognostic (4.90e-2)" "unprognostic (1.57e-1)" "unprognostic (3.76e-1)" "unprognostic (4.32e-3)" "unprognostic (1.97e-2)" "unprognostic (7.75e-2)" "unprognostic (9.68e-2)" "unprognostic (2.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-2)" P4HA2 "C-P4Halpha(II), lncRNA-PE" ENSG00000072682 "Prolyl 4-hydroxylase subunit alpha 2" O15460 5 132190147-132295315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 128.3;Basal respiratory cells: 103.4;Endometrial stromal cells: 102.3;Pancreatic endocrine cells: 107.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016997, HPA027824, CAB062557" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme No No 13000 "Cluster 35: Neutrophils - Protein binding" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 3 "Endoplasmic reticulum, Vesicles" "CAB062557: AB_2665641, HPA016997: AB_2669501, HPA027824: AB_2672402" "unprognostic (1.30e-3)" "prognostic unfavorable (1.24e-5)" "unprognostic (2.56e-3)" "unprognostic (1.28e-3)" "unprognostic (2.08e-3)" "unprognostic (1.62e-3)" "unprognostic (1.16e-3)" "unprognostic (1.93e-3)" "unprognostic (2.83e-2)" "unprognostic (1.92e-1)" "unprognostic (8.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (2.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.12e-4)" PANK4 FLJ10782 ENSG00000157881 "Pantothenate kinase 4 (inactive)" Q9NVE7 1 2508537-2526597 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" Hydrolase Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.7" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011723, HPA012036, HPA027961" Uncertain Approved Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 79: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 49: Non-specific - Transcription" Cytosol "HPA011723: AB_2668522, HPA012036: AB_1854952, HPA027961: AB_10602042" "unprognostic (1.23e-1)" "unprognostic (2.31e-1)" "unprognostic (3.36e-1)" "unprognostic (1.13e-1)" "unprognostic (4.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-1)" "unprognostic (6.51e-2)" "unprognostic (1.80e-1)" "unprognostic (1.18e-2)" "unprognostic (3.29e-2)" "prognostic favorable (1.57e-5)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (2.25e-1)" "unprognostic (8.15e-2)" PAX6 "AN, AN1, AN2, D11S812E, WAGR" ENSG00000007372 "Paired box 6" P26367 11 31784779-31817961 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 81.6;retina: 66.8" "Group enriched" "Detected in some" 6 "Horizontal cells: 473.4;Muller glia cells: 408.8" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Region enhanced" "Detected in all" "cerebellum: 96.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Spermatocytes" "Region enhanced" "Detected in all" "cerebellum: 54.3" "Low region specificity" "Detected in all" "HPA030775, CAB034143" Enhanced Supported Enhanced Nucleoplasm NA NA "Cluster 28: Neuronal - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 79 Nucleoplasm "CAB034143: AB_1127044, HPA030775: AB_10601243" "unprognostic (2.89e-1)" "unprognostic (2.98e-2)" "unprognostic (8.34e-2)" "unprognostic (3.85e-2)" "unprognostic (4.42e-2)" "unprognostic (7.82e-2)" "unprognostic (2.76e-1)" "unprognostic (1.91e-1)" "unprognostic (4.24e-3)" "unprognostic (1.68e-1)" "unprognostic (1.20e-2)" "unprognostic (3.91e-1)" "unprognostic (8.96e-2)" "unprognostic (1.32e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (3.42e-3)" PCDH15 "CDHR15, DFNB23, USH1F" ENSG00000150275 "Protocadherin related 15" Q96QU1 10 53802771-55627942 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Hearing" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 18.4;retina: 59.9" "Cell type enriched" "Detected in some" 13 "Oligodendrocyte precursor cells: 2782.3" "Cancer enriched" "Detected in single" 9 "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 6.3" "Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA074437 Supported "Intracellular and membrane" "Cell adhesion" NA NA 22000 "Cluster 76: Retina - Visual perception" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA074437: " "unprognostic (1.38e-1)" "unprognostic (3.39e-1)" "unprognostic (8.15e-5)" "unprognostic (3.07e-3)" "unprognostic (2.79e-1)" "unprognostic (9.15e-4)" "unprognostic (2.02e-1)" "unprognostic (3.89e-2)" "unprognostic (1.12e-3)" "unprognostic (1.31e-3)" "unprognostic (1.19e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-1)" "unprognostic (7.66e-3)" PDE6A "PDEA, RP43" ENSG00000132915 "Phosphodiesterase 6A" P16499 5 149857953-149944793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 66 "retina: 1047.0" "Cell type enriched" "Detected in many" 9 "Rod photoreceptor cells: 2813.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA016970, HPA074677" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA016970: AB_1855125, HPA074677: AB_2732264" "unprognostic (6.85e-2)" "unprognostic (8.84e-2)" "unprognostic (1.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (4.39e-3)" "unprognostic (8.83e-2)" "unprognostic (6.54e-2)" "unprognostic (5.91e-3)" "unprognostic (1.77e-2)" "unprognostic (9.21e-2)" "unprognostic (7.57e-5)" "unprognostic (9.93e-2)" "unprognostic (3.08e-1)" "unprognostic (1.31e-1)" "unprognostic (2.26e-2)" PDE6B "CSNB3, CSNBAD2, PDEB, rd1, RP40" ENSG00000133256 "Phosphodiesterase 6B" P35913 4 625573-670782 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "retina: 373.2" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 434.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054148, HPA059929" Enhanced Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Retina - Visual perception" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" Cytosol "HPA054148: AB_2682401, HPA059929: AB_2684166" "unprognostic (2.43e-2)" "unprognostic (1.33e-4)" "unprognostic (2.45e-4)" "unprognostic (7.18e-3)" "unprognostic (1.88e-2)" "unprognostic (5.04e-3)" "unprognostic (7.32e-3)" "prognostic favorable (5.34e-4)" "unprognostic (9.70e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-2)" "unprognostic (2.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.67e-2)" "unprognostic (2.26e-1)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" PDE6G "PDEG, RP57" ENSG00000185527 "Phosphodiesterase 6G" P18545 17 81650459-81663112 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 99 "retina: 1986.8" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 3542.6" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 6 "basophil: 127.6;NK-cell: 220.8" "Group enriched" "Detected in all" 6 "granulocytes: 127.6;NK-cells: 220.8" "Group enriched" "Detected in some" 5 "Leukemia: 12.6;testis cancer: 5.7" "Thyroid - T-cells" "Region enhanced" "Detected in some" "hippocampal formation: 4.7" "Low region specificity" "Detected in some" HPA045118 Supported Uncertain Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Retina - Visual perception" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Photoreceptor cells - Visual perception" 3 Vesicles "HPA045118: AB_2732517" "unprognostic (6.16e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.51e-3)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "unprognostic (6.33e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (4.85e-2)" "unprognostic (5.01e-2)" "unprognostic (1.94e-2)" "unprognostic (5.71e-2)" "unprognostic (5.44e-2)" "unprognostic (2.73e-1)" "unprognostic (1.14e-1)" PDE6H ENSG00000139053 "Phosphodiesterase 6H" Q13956 12 14973042-14981865 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 82 "retina: 883.2" "Cell type enriched" "Detected in some" 39 "Cone photoreceptor cells: 6935.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 4.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Brain cancer: 2.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA045118 Supported Uncertain Vesicles NA NA "Cluster 76: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 5 Vesicles "HPA045118: AB_2732517" "unprognostic (1.47e-3)" "unprognostic (1.07e-2)" PDZD7 "bA108L7.8, DFNB57, FLJ23209, PDZK7" ENSG00000186862 "PDZ domain containing 7" Q9H5P4 10 101007679-101032295 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 17.3;intestine: 19.4;pituitary gland: 5.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.4;Excitatory neurons: 31.2;Horizontal cells: 25.2;Inhibitory neurons: 15.8;Proximal enterocytes: 60.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074542 Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 80: Non-specific - Endocytosis" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 22: Proximal enterocytes - Digestion" 1 Nucleoplasm "HPA074542: " "unprognostic (1.46e-1)" "unprognostic (2.85e-3)" "unprognostic (3.96e-2)" "unprognostic (2.10e-1)" "unprognostic (2.15e-2)" "unprognostic (2.83e-2)" "unprognostic (1.38e-2)" "unprognostic (5.31e-2)" "unprognostic (2.52e-2)" "unprognostic (2.95e-2)" "unprognostic (2.45e-1)" "unprognostic (1.87e-3)" "unprognostic (3.54e-3)" "unprognostic (3.89e-1)" "unprognostic (1.79e-1)" "unprognostic (3.51e-2)" "unprognostic (2.80e-1)" PHOX2A "ARIX, CFEOM2, FEOM2, PMX2A" ENSG00000165462 "Paired like homeobox 2A" O14813 11 72239077-72245664 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "adrenal gland: 19.3" "Cell type enriched" "Detected in single" 4 "Spermatogonia: 3.4" "Cancer enriched" "Detected in some" 9 "ovarian cancer: 9.3" "Region enriched" "Detected in some" 9 "pons: 38.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 755 "Neuroblastoma: 337.6" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053810, HPA065621, HPA078004" Enhanced Supported Nucleoplasm No NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 10: Muller glia cells - Visual perception" 2 Nucleoplasm "HPA053810: , HPA065621: AB_2685522, HPA078004: AB_2732367" "unprognostic (5.84e-2)" "unprognostic (8.51e-2)" "unprognostic (5.07e-2)" "unprognostic (2.19e-1)" "unprognostic (2.13e-1)" "unprognostic (9.92e-4)" "unprognostic (3.03e-2)" PIKFYVE "FAB1, KIAA0981, MGC40423, p235, PIP5K, PIP5K3, ZFYVE29" ENSG00000115020 "Phosphoinositide kinase, FYVE-type zinc finger containing" Q9Y2I7 2 208266255-208358746 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Lipid metabolism" "Kinase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 75.9;Oligodendrocytes: 76.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042604 Uncertain NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 40: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 73: B-cells - B-cell function" 1 "HPA042604: AB_10796580" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.88e-1)" "unprognostic (3.03e-1)" "unprognostic (2.04e-2)" "prognostic favorable (6.81e-4)" "unprognostic (6.82e-3)" "unprognostic (6.45e-2)" "unprognostic (1.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.77e-1)" "unprognostic (2.10e-2)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (3.29e-1)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" PITPNM3 "ACKR6, CORD5, NIR1, RDGBA3" ENSG00000091622 "PITPNM family member 3" Q9BZ71 17 6451263-6556555 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.4;lymphoid tissue: 59.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 19.8;Inhibitory neurons: 23.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Low cancer specificity" "Detected in many" "Liver - Sinusoid Endothelial cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022432, HPA059005" Enhanced Approved "Plasma membrane" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 6: Ovarian stromal cells - Transcription" 1 "Plasma membrane" "HPA022432: AB_2670936, HPA059005: AB_2683876" "unprognostic (2.97e-2)" "unprognostic (8.60e-3)" "unprognostic (1.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.69e-2)" "prognostic favorable (3.67e-6)" "unprognostic (1.25e-2)" "unprognostic (6.86e-2)" "unprognostic (3.66e-2)" "unprognostic (3.01e-2)" "unprognostic (2.99e-3)" "unprognostic (3.58e-2)" "unprognostic (2.41e-1)" "unprognostic (9.60e-2)" "unprognostic (1.61e-1)" "unprognostic (3.55e-1)" "unprognostic (2.63e-1)" PITX2 "ARP1, Brx1, IGDS, IHG2, IRID2, Otlx2, RGS, RIEG, RIEG1, RS" ENSG00000164093 "Paired like homeodomain 2" Q99697 4 110617423-110642123 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 40.6;skeletal muscle: 41.6;tongue: 27.0;urinary bladder: 28.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 28.8;Cardiomyocytes: 18.5;Paneth cells: 27.1;Proximal enterocytes: 39.6;Skeletal myocytes: 70.3;Smooth muscle cells: 38.2;Suprabasal keratinocytes: 36.9" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "hypothalamus: 29.9;thalamus: 10.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 23 "hypothalamus: 8.6;midbrain: 2.3" "HPA050074, HPA062728" Enhanced Nucleoplasm NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 50: Connective tissue cells - ECM organization" 1 Nucleoplasm "HPA050074: AB_2681005, HPA062728: AB_2684851" "unprognostic (1.08e-1)" "unprognostic (1.23e-2)" "unprognostic (9.29e-2)" "unprognostic (9.24e-2)" "unprognostic (1.68e-1)" "unprognostic (1.14e-2)" "unprognostic (9.61e-4)" "unprognostic (3.22e-2)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.16e-1)" "unprognostic (2.77e-1)" "unprognostic (1.11e-15)" "unprognostic (6.97e-3)" "unprognostic (1.43e-1)" "unprognostic (5.98e-2)" "unprognostic (9.91e-2)" PLA2G5 ENSG00000127472 "Phospholipase A2 group V" P39877 1 20028179-20091911 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism, Phagocytosis, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 57.3;heart muscle: 128.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 87.9;Cone photoreceptor cells: 149.5;Leydig cells: 82.7;Ovarian stromal cells: 52.3;Peritubular cells: 78.1;Sertoli cells: 108.8" "Group enriched" "Detected in many" 5 "glioma: 13.0;prostate cancer: 3.5" "Region enhanced" "Detected in all" "choroid plexus: 32.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA053361 Approved "Secreted in other tissues" Enzyme NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 72: Neuronal - Signal transduction" "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA053361: AB_2682127" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (5.68e-3)" "unprognostic (6.16e-2)" "unprognostic (2.01e-2)" "unprognostic (5.93e-2)" "unprognostic (2.12e-2)" "unprognostic (1.02e-1)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.70e-3)" "unprognostic (6.00e-5)" "unprognostic (2.87e-2)" "unprognostic (3.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.97e-3)" POLG "POLG1, POLGA" ENSG00000140521 "DNA polymerase gamma, catalytic subunit" P54098 15 89305198-89334861 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA replication" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 69.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056821, HPA078482" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 28: Dendritic cells - Antigen presentation" 1 Mitochondria "HPA056821: AB_2683247, HPA078482: " "unprognostic (1.87e-1)" "unprognostic (4.71e-2)" "unprognostic (2.61e-2)" "unprognostic (3.64e-1)" "unprognostic (1.62e-1)" "unprognostic (3.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.63e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.65e-3)" "unprognostic (1.58e-2)" "unprognostic (4.29e-2)" "unprognostic (2.07e-1)" "unprognostic (3.45e-1)" POLG2 "HP55, MTPOLB" ENSG00000256525 "DNA polymerase gamma 2, accessory subunit" Q9UHN1 17 64477785-64497054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017030, HPA023202, HPA078396" Approved Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 18: Non-specific - Translation" "Cluster 78: Testis - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 80: Non-specific - Transcription" 1 Mitochondria "Nuclear bodies" "CAB017030: , HPA023202: AB_1855523, HPA078396: " "unprognostic (1.76e-1)" "unprognostic (2.20e-1)" "unprognostic (1.59e-1)" "unprognostic (7.02e-2)" "unprognostic (6.01e-2)" "unprognostic (2.91e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (4.38e-2)" "unprognostic (8.46e-2)" "unprognostic (3.14e-1)" "unprognostic (5.17e-3)" "prognostic unfavorable (6.59e-4)" "prognostic unfavorable (1.17e-5)" "unprognostic (5.17e-2)" "unprognostic (1.58e-1)" "unprognostic (2.88e-2)" "unprognostic (4.82e-2)" POMGNT1 "FLJ20277, LGMD2O, MEB, MGAT1.2" ENSG00000085998 "Protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)" Q8WZA1 1 46188683-46220305 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044518 Approved NA NA 17000000 "Cluster 25: Non-specific - Unknown function" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Non-specific - Mixed function" 6 "HPA044518: AB_10795985" "unprognostic (4.59e-3)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "unprognostic (3.20e-1)" "prognostic unfavorable (3.52e-4)" "unprognostic (1.82e-1)" "unprognostic (5.74e-2)" "unprognostic (5.37e-2)" "prognostic favorable (4.27e-4)" "unprognostic (5.86e-2)" "unprognostic (4.39e-2)" "unprognostic (4.99e-3)" "unprognostic (1.72e-1)" "unprognostic (2.16e-2)" "unprognostic (2.36e-1)" PON1 "ESA, PON" ENSG00000005421 "Paraoxonase 1" P27169 7 95297676-95324532 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 103 "liver: 516.3" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 428.5" "Cancer enriched" "Detected in some" 78 "liver cancer: 97.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 1.0;prostate cancer: 2.4" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001610 Approved "Secreted to blood" Enzyme NA NA 96000000000 17000000000 "Cluster 31: Liver - Plasma proteins" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 43: Hepatocytes - Metabolism" "HPA001610: AB_1079656" "unprognostic (2.02e-2)" "unprognostic (2.41e-2)" "unprognostic (3.04e-1)" "unprognostic (3.54e-2)" "unprognostic (2.70e-1)" "prognostic favorable (7.24e-7)" "unprognostic (2.24e-1)" "unprognostic (1.95e-1)" "unprognostic (9.02e-3)" "unprognostic (1.76e-3)" "unprognostic (3.97e-2)" "unprognostic (6.74e-9)" "unprognostic (1.09e-3)" "unprognostic (2.29e-2)" "unprognostic (2.07e-1)" "unprognostic (5.54e-3)" PRIMPOL "CCDC111, FLJ33167" ENSG00000164306 "Primase and DNA directed polymerase" Q96LW4 4 184649667-184694963 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 71.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 24.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 24.1" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054372 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 16: Intestinal goblet cells - Mucin production" 4 Cytosol Nucleoplasm "HPA054372: AB_2682466" "unprognostic (1.68e-1)" "unprognostic (1.27e-3)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (2.67e-2)" "unprognostic (4.75e-2)" "unprognostic (2.02e-2)" "unprognostic (3.34e-2)" "unprognostic (3.32e-3)" "unprognostic (5.86e-2)" "unprognostic (2.52e-2)" "unprognostic (5.02e-1)" "unprognostic (3.04e-1)" "unprognostic (3.04e-2)" "unprognostic (3.81e-1)" "unprognostic (1.49e-1)" "unprognostic (1.05e-1)" PROM1 "AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4" ENSG00000007062 "Prominin 1" O43490 4 15963076-16084378 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 264.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 300.7;Mucus glandular cells: 169.5;Rod photoreceptor cells: 329.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine cancer: 32.2" "Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004922, CAB011525, HPA031053, CAB080375, CAB080376" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 47: Endothelial cells - Vasculature" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 66: Photoreceptor cells - Visual perception" 1 "CAB011525: AB_470302, CAB080375: , CAB080376: , HPA004922: AB_1846238, HPA031053: AB_2673713" "unprognostic (6.33e-2)" "unprognostic (2.54e-1)" "unprognostic (1.53e-1)" "unprognostic (3.39e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-1)" "unprognostic (2.39e-1)" "unprognostic (6.64e-2)" "unprognostic (2.18e-2)" "unprognostic (2.17e-1)" "unprognostic (1.21e-2)" "unprognostic (9.06e-2)" "prognostic favorable (2.56e-5)" "unprognostic (2.16e-2)" "unprognostic (1.02e-1)" "unprognostic (9.38e-2)" "unprognostic (1.17e-1)" PRPF3 "hPrp3, Prp3, RP18, SNRNP90" ENSG00000117360 "Pre-mRNA processing factor 3" O43395 1 150321479-150353233 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027226, HPA067116" Approved Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 55: Non-specific - Transcription" 35 Nucleoplasm "HPA027226: AB_1855770, HPA067116: AB_2685783" "unprognostic (2.75e-1)" "unprognostic (3.00e-1)" "unprognostic (2.20e-1)" "unprognostic (2.77e-1)" "unprognostic (1.78e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.59e-5)" "unprognostic (7.89e-2)" "unprognostic (7.13e-3)" "unprognostic (1.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (3.19e-5)" "unprognostic (6.77e-3)" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (7.78e-3)" PRPF31 "hPrp31, NY-BR-99, PRP31, RP11, SNRNP61" ENSG00000105618 "Pre-mRNA processing factor 31" Q8WWY3 19 54115410-54131719 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041939, HPA061873" Supported Supported Nucleoplasm NA NA 13000 "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 39: Non-specific - Basic cellular processes" 118 Nucleoplasm "HPA041939: AB_10793938, HPA061873: AB_2684630" "unprognostic (1.32e-1)" "unprognostic (1.73e-2)" "unprognostic (1.26e-2)" "unprognostic (7.98e-2)" "unprognostic (1.28e-1)" "unprognostic (3.28e-2)" "prognostic unfavorable (7.33e-4)" "unprognostic (9.55e-2)" "unprognostic (2.16e-1)" "unprognostic (1.66e-1)" "unprognostic (5.26e-3)" "unprognostic (1.81e-2)" "unprognostic (2.06e-1)" "unprognostic (2.16e-1)" "unprognostic (5.94e-2)" "unprognostic (2.53e-1)" "unprognostic (7.04e-2)" PRPF4 "HPRP4, HPRP4P, PRP4, Prp4p, SNRNP60" ENSG00000136875 "Pre-mRNA processing factor 4" O43172 9 113275642-113294009 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021794, HPA022248" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mitochondria" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" 15 "Nuclear speckles" "HPA021794: AB_1855772, HPA022248: AB_1855773" "unprognostic (1.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.60e-2)" "unprognostic (1.36e-1)" "unprognostic (1.69e-1)" "unprognostic (3.70e-3)" "prognostic unfavorable (9.35e-4)" "unprognostic (1.95e-2)" "unprognostic (6.57e-2)" "unprognostic (3.14e-2)" "unprognostic (5.00e-2)" "unprognostic (6.76e-3)" "unprognostic (2.18e-3)" "unprognostic (4.43e-2)" "unprognostic (1.29e-1)" "unprognostic (1.42e-1)" "unprognostic (1.57e-2)" PRPF6 "ANT-1, bB152O15.1, C20orf14, hPrp6, Prp6, RP60, SNRNP102, TOM, U5-102K" ENSG00000101161 "Pre-mRNA processing factor 6" O94906 20 63981132-64033100 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047106 Supported Supported "Nuclear speckles" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 79: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 55: Non-specific - Transcription" 16 "Nuclear speckles" "HPA047106: AB_10963084" "unprognostic (1.29e-1)" "unprognostic (9.96e-3)" "unprognostic (7.02e-2)" "unprognostic (9.36e-3)" "unprognostic (1.80e-1)" "unprognostic (2.34e-1)" "unprognostic (1.66e-3)" "unprognostic (3.37e-2)" "unprognostic (1.44e-2)" "unprognostic (1.14e-1)" "unprognostic (5.76e-3)" "unprognostic (2.18e-1)" "unprognostic (3.16e-3)" "unprognostic (6.16e-2)" "unprognostic (8.04e-2)" "unprognostic (7.19e-2)" "unprognostic (5.39e-3)" PRPF8 "hPrp8, Prp8, PRPC8, RP13, SNRNP220" ENSG00000174231 "Pre-mRNA processing factor 8" Q6P2Q9 17 1650629-1684867 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Cancer-related genes, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 290.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009941, CAB015457" Supported Supported Nucleoplasm NA NA 120000 "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" 19 Nucleoplasm "CAB009941: AB_2171185, CAB015457: AB_831685" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-2)" "unprognostic (3.13e-2)" "unprognostic (1.56e-1)" "unprognostic (4.94e-2)" "unprognostic (6.58e-2)" "unprognostic (1.56e-1)" "unprognostic (4.19e-2)" "unprognostic (1.77e-1)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (2.45e-3)" "unprognostic (2.00e-1)" "unprognostic (2.66e-1)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" PRPH2 "CACD2, rd2, RDS, RP7, TSPAN22" ENSG00000112619 "Peripherin 2" P23942 6 42696598-42722597 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "retina: 621.9" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 270.2;Rod photoreceptor cells: 443.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.5;Sarcoma: 1.5" "Prostate - Fibroblasts" "Region enriched" "Detected in single" 7 "hippocampal formation: 2.4" "Not detected" "Not detected" HPA029458 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 2 "HPA029458: AB_10602193" "unprognostic (2.37e-1)" "unprognostic (4.88e-2)" "unprognostic (6.67e-2)" "unprognostic (8.43e-2)" "unprognostic (1.15e-1)" "unprognostic (2.87e-3)" "unprognostic (4.73e-1)" "unprognostic (1.85e-1)" "unprognostic (6.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (3.18e-2)" "unprognostic (7.07e-4)" "unprognostic (1.13e-3)" "unprognostic (1.59e-1)" "unprognostic (8.42e-2)" "unprognostic (8.96e-3)" RAB28 ENSG00000157869 "RAB28, member RAS oncogene family" P51157 4 13361354-13484365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 115.9;Inhibitory neurons: 134.5;Spermatocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044575 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 31: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 65: Neurons - Synaptic function" 6 "HPA044575: AB_10959460" "unprognostic (2.10e-1)" "unprognostic (1.95e-1)" "unprognostic (1.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.17e-1)" "unprognostic (2.46e-2)" "unprognostic (3.90e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-1)" "unprognostic (3.69e-2)" "unprognostic (2.09e-2)" "unprognostic (1.07e-1)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (5.31e-3)" "prognostic favorable (1.61e-4)" RAX2 "ARMD6, CORD11, MGC15631, RAXL1" ENSG00000173976 "Retina and anterior neural fold homeobox 2" Q96IS3 19 3769089-3772228 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" DNA-binding "Age-related macular degeneration, Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "retina: 62.5" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 195.4;Rod photoreceptor cells: 201.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Uterine cancer: 1.9" "Low region specificity" "Detected in all" HPA052533 Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 76: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA052533: AB_2681862" "unprognostic (5.53e-2)" "unprognostic (1.39e-2)" "unprognostic (4.48e-1)" RBP3 "D10S64, D10S65, D10S66, RP66" ENSG00000265203 "Retinol binding protein 3" P10745 10 47348363-47357881 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transport "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 179 "retina: 525.9" "Group enriched" "Detected in some" 11 "Bipolar cells: 444.0;Cone photoreceptor cells: 1364.4;Rod photoreceptor cells: 1741.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Low region specificity" "Detected in many" "HPA041301, HPA044239" Enhanced "Secreted in other tissues" Transport NA NA "Cluster 76: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 9 "HPA041301: AB_2677398, HPA044239: AB_2678868" "unprognostic (3.48e-2)" "unprognostic (4.78e-3)" "unprognostic (1.36e-2)" "unprognostic (4.02e-2)" "unprognostic (1.40e-1)" "unprognostic (1.58e-2)" "unprognostic (5.09e-2)" "unprognostic (5.14e-3)" "unprognostic (7.44e-2)" "unprognostic (1.23e-1)" "unprognostic (4.68e-3)" RD3 "C1orf36, LCA12" ENSG00000198570 "RD3 regulator of GUCY2D" Q7Z3Z2 1 211476522-211492162 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "retina: 45.7" "Group enriched" "Detected in some" 5 "Bipolar cells: 67.1;Cone photoreceptor cells: 144.4;Rod photoreceptor cells: 55.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 5.7;Uterine cancer: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029941, HPA029943" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 5 "HPA029941: AB_2732449, HPA029943: AB_2732450" "unprognostic (1.42e-1)" "unprognostic (2.75e-2)" "unprognostic (1.14e-2)" "unprognostic (6.07e-2)" "unprognostic (2.96e-2)" "unprognostic (2.18e-1)" "unprognostic (9.54e-2)" "unprognostic (7.87e-2)" "unprognostic (1.15e-1)" "unprognostic (4.80e-2)" "unprognostic (4.58e-2)" "unprognostic (2.86e-2)" RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 91.2;liver: 57.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 34.0;Proximal enterocytes: 35.7;Rod photoreceptor cells: 72.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 11: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 66: Photoreceptor cells - Visual perception" 1 Vesicles "HPA063345: AB_2684992" "unprognostic (1.04e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.05e-1)" "unprognostic (1.26e-3)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (3.46e-2)" "unprognostic (2.12e-3)" "unprognostic (3.27e-2)" REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 211.2;liver: 388.3;testis: 276.0" "Group enriched" "Detected in many" 5 "Late spermatids: 3055.8;Proximal enterocytes: 905.4" "Cancer enhanced" "Detected in all" "liver cancer: 114.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Late spermatids" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 46: Testis - Spermatogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 36: Late spermatids - Unknown function" 11 "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA048015: AB_2680233" "unprognostic (1.21e-1)" "unprognostic (1.56e-1)" "unprognostic (7.76e-2)" "unprognostic (1.63e-3)" "unprognostic (3.24e-1)" "unprognostic (2.43e-2)" "unprognostic (1.92e-1)" "unprognostic (6.85e-2)" "unprognostic (7.38e-2)" "unprognostic (4.56e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.40e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (2.83e-1)" "unprognostic (5.38e-2)" RGR RP44 ENSG00000148604 "Retinal G protein coupled receptor" P47804 10 84230666-84259960 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 134.8" "Cell type enriched" "Detected in some" 39 "Muller glia cells: 1357.4" "Cancer enriched" "Detected in single" 4 "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "midbrain: 25.5;olfactory bulb: 55.9;thalamus: 29.6" HPA059149 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 1 Vesicles "Plasma membrane, Cytosol" "HPA059149: " "unprognostic (9.28e-2)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (9.53e-2)" "unprognostic (4.57e-2)" "unprognostic (1.57e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-1)" RGS9 "MGC111763, MGC26458, PERRS, RGS9L" ENSG00000108370 "Regulator of G protein signaling 9" O75916 17 65100812-65227703 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 66.0" "Group enriched" "Detected in many" 9 "Cone photoreceptor cells: 280.4;Rod photoreceptor cells: 484.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 42.2" "Group enriched" "Detected in some" 6 "gdT-cell: 9.8;MAIT T-cell: 2.5;memory CD8 T-cell: 6.8;naive CD8 T-cell: 3.2;NK-cell: 4.0" "Group enriched" "Detected in many" 42 "NK-cells: 4.0;T-cells: 9.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 9 "basal ganglia: 248.2" "Region enriched" "Detected in all" 10 "basal ganglia: 139.6" "HPA013550, HPA014137" Enhanced Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 66: Photoreceptor cells - Visual perception" "Nucleoplasm, Vesicles" "HPA013550: , HPA014137: AB_2668943" "unprognostic (4.43e-3)" "unprognostic (7.49e-3)" "unprognostic (5.12e-2)" "unprognostic (3.09e-5)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.20e-1)" "unprognostic (4.88e-2)" "prognostic favorable (1.35e-4)" "unprognostic (1.07e-1)" "unprognostic (5.07e-2)" "unprognostic (4.94e-2)" "unprognostic (3.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.49e-1)" RGS9BP "FLJ45744, PERRS, R9AP" ENSG00000186326 "Regulator of G protein signaling 9 binding protein" Q6ZS82 19 32675848-32678300 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 12.2;retina: 16.8;skeletal muscle: 8.7" "Group enriched" "Detected in some" 10 "Bipolar cells: 31.3;Cone photoreceptor cells: 91.8;Rod photoreceptor cells: 66.8" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "choroid plexus: 62.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049791 Enhanced Approved "Plasma membrane" NA NA "Cluster 3: Non-specific - Unknown function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" "HPA049791: AB_2680884" "unprognostic (2.82e-2)" "unprognostic (6.99e-3)" "unprognostic (2.44e-3)" "unprognostic (1.20e-7)" "unprognostic (1.49e-1)" "unprognostic (1.21e-2)" "unprognostic (1.17e-2)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (6.71e-2)" "unprognostic (6.74e-2)" "unprognostic (3.89e-2)" "unprognostic (1.63e-3)" "unprognostic (2.29e-1)" "unprognostic (8.22e-2)" "unprognostic (5.23e-2)" "unprognostic (5.34e-2)" RHO "CSNBAD1, OPN2, RP4" ENSG00000163914 Rhodopsin P08100 3 129528639-129535344 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8215 "retina: 3936.5" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 3749.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 4 "hippocampal formation: 9.7" "Region enhanced" "Detected in some" "cerebral cortex: 1.0;hippocampal formation: 1.5" "HPA013440, CAB022486, CAB034887, CAB034888" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 66: Photoreceptor cells - Visual perception" 2 "CAB022486: , CAB034887: AB_785511, CAB034888: AB_785512, HPA013440: AB_2668844" "unprognostic (4.32e-2)" "unprognostic (1.21e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (2.87e-1)" "unprognostic (1.94e-1)" "unprognostic (9.19e-11)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (2.91e-1)" RIMS1 "CORD7, KIAA0340, RAB3IP2, RIM, RIM1" ENSG00000079841 "Regulating synaptic membrane exocytosis 1" Q86UR5 6 71886550-72403150 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 63.6" "Group enriched" "Detected in many" 4 "Excitatory neurons: 630.9;Inhibitory neurons: 547.9;Oligodendrocyte precursor cells: 303.3" "Cancer enhanced" "Detected in single" "prostate cancer: 0.7" "Region enriched" "Detected in all" 7 "cerebellum: 849.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.6;prostate cancer: 3.7" "Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 470.0" HPA076565 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Neurons - Synaptic function" "HPA076565: " "unprognostic (1.34e-3)" "unprognostic (3.47e-1)" "unprognostic (1.48e-1)" "unprognostic (1.63e-3)" "unprognostic (6.62e-2)" "unprognostic (1.16e-1)" "unprognostic (1.73e-2)" "unprognostic (8.57e-2)" "unprognostic (2.85e-1)" "unprognostic (7.76e-4)" "unprognostic (2.42e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-2)" "unprognostic (2.76e-1)" "unprognostic (5.74e-2)" "unprognostic (1.07e-2)" RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500610-104254430 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 46.7;brain: 48.1;retina: 76.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 354.4;Cone photoreceptor cells: 625.3;Excitatory neurons: 1535.6;Inhibitory neurons: 1182.6;Oligodendrocyte precursor cells: 541.5;Rod photoreceptor cells: 1052.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.3" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: AB_2685678" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (4.47e-2)" "unprognostic (5.51e-2)" "unprognostic (2.82e-1)" "unprognostic (7.09e-3)" "unprognostic (2.02e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (8.01e-3)" "unprognostic (1.40e-2)" "unprognostic (6.34e-2)" "unprognostic (1.67e-5)" "unprognostic (8.12e-4)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" RLBP1 CRALBP ENSG00000140522 "Retinaldehyde binding protein 1" P12271 15 89209869-89221614 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Transport, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "retina: 257.5" "Cell type enriched" "Detected in some" 68 "Muller glia cells: 2832.0" "Group enriched" "Detected in some" 30 "glioma: 3.7;melanoma: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Bile duct cancer: 10.4;colorectal cancer: 3.5;skin cancer: 9.4" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042051, HPA044083" Enhanced Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 76: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 10: Muller glia cells - Visual perception" Cytosol "Nucleoplasm, Centrosome" "HPA042051: AB_2732495, HPA044083: AB_2678802" "unprognostic (3.19e-2)" "unprognostic (2.66e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (8.68e-2)" "unprognostic (1.76e-1)" "unprognostic (8.24e-3)" "unprognostic (5.21e-2)" "unprognostic (3.17e-1)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.78e-1)" "unprognostic (1.13e-1)" "unprognostic (8.42e-2)" ROM1 "ROM, TSPAN23" ENSG00000149489 "Retinal outer segment membrane protein 1" Q03395 11 62611722-62615116 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 18 "retina: 1150.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 642.5;Cone photoreceptor cells: 717.0;Muller glia cells: 405.0;Rod photoreceptor cells: 2757.9" "Cancer enriched" "Detected in all" 6 "glioma: 14.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.7" "Group enriched" "Detected in many" 4 "NK-cells: 2.7;T-cells: 1.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028910, HPA073279" Enhanced Approved "Plasma membrane,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 76: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 66: Photoreceptor cells - Visual perception" 3 "Plasma membrane, Cytosol" "HPA028910: AB_2672824, HPA073279: " "unprognostic (1.54e-2)" "unprognostic (1.37e-2)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-1)" "unprognostic (4.05e-1)" "prognostic favorable (2.20e-4)" "unprognostic (2.20e-1)" "unprognostic (9.87e-2)" "unprognostic (7.65e-3)" "unprognostic (3.50e-2)" "prognostic unfavorable (2.85e-6)" "unprognostic (2.61e-1)" "unprognostic (4.65e-1)" "unprognostic (1.02e-1)" "unprognostic (7.24e-2)" RP1 "DCDC4A, ORP1" ENSG00000104237 "RP1 axonemal microtubule associated" P56715 8 54509422-54871720 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "retina: 229.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 163.0;Ciliated cells: 171.6;Cone photoreceptor cells: 392.5;Rod photoreceptor cells: 955.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Stomach - Parietal cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 2.9" HPA042257 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 46: Brainstem - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 66: Photoreceptor cells - Visual perception" "HPA042257: AB_10797385" "unprognostic (3.19e-3)" "unprognostic (2.63e-3)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (1.70e-1)" "unprognostic (9.16e-3)" "unprognostic (6.24e-2)" "unprognostic (4.56e-2)" "unprognostic (4.13e-5)" "unprognostic (2.48e-1)" "unprognostic (2.16e-5)" "unprognostic (8.92e-2)" "unprognostic (6.18e-2)" "unprognostic (1.89e-2)" "unprognostic (8.96e-2)" RP1L1 DCDC4B ENSG00000183638 "RP1 like 1" Q8IWN7 8 10606349-10712187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 114 "retina: 42.8" "Group enriched" "Detected in some" 14 "Cone photoreceptor cells: 124.0;Rod photoreceptor cells: 65.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024686, HPA024744" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" "HPA024686: AB_2671650, HPA024744: AB_2671668" "unprognostic (3.27e-1)" "unprognostic (9.97e-2)" "unprognostic (1.24e-1)" "unprognostic (6.41e-2)" "unprognostic (2.04e-1)" "unprognostic (1.36e-1)" "unprognostic (2.37e-1)" "unprognostic (1.98e-5)" "unprognostic (3.57e-1)" "unprognostic (5.22e-2)" "unprognostic (2.08e-4)" "unprognostic (8.52e-2)" "unprognostic (5.77e-2)" "unprognostic (6.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.02e-2)" "unprognostic (2.82e-1)" RP2 "NM23-H10, NME10, TBCCD2" ENSG00000102218 "RP2 activator of ARL3 GTPase" O75695 X 46837043-46882358 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.9" "Cell type enhanced" "Detected in many" "Kupffer cells: 60.7;Langerhans cells: 86.3;monocytes: 173.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000234, HPA000909" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 22: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Monocytes - Innate immune response" 3 "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA000234: AB_1079831, HPA000909: AB_2666140" "unprognostic (2.26e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-2)" "unprognostic (2.98e-1)" "unprognostic (1.69e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.97e-4)" "unprognostic (2.58e-2)" "unprognostic (9.76e-3)" "unprognostic (3.10e-2)" "unprognostic (3.79e-3)" "unprognostic (9.75e-2)" "unprognostic (6.15e-3)" "unprognostic (2.96e-2)" "unprognostic (9.66e-2)" "unprognostic (1.61e-1)" "unprognostic (4.28e-3)" RP9 PAP-1 ENSG00000164610 "RP9 pre-mRNA splicing factor" Q8TA86 7 33094797-33109405 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031523, HPA050778" Uncertain Enhanced Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 73: B-cells - B-cell function" 6 Nucleoplasm "Vesicles, Cytosol" "HPA031523: AB_10603235, HPA050778: AB_2681233" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (1.07e-2)" "unprognostic (1.82e-1)" "unprognostic (6.65e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.58e-4)" "unprognostic (6.71e-2)" "unprognostic (6.22e-2)" "unprognostic (7.53e-2)" "unprognostic (7.03e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.65e-5)" "unprognostic (4.19e-2)" "unprognostic (2.63e-2)" "unprognostic (2.70e-1)" "unprognostic (1.61e-1)" RPGR "COD1, CORDX1, CRD, RP15, RP3" ENSG00000156313 "Retinitis pigmentosa GTPase regulator" Q92834 X 38269163-38327544 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Guanine-nucleotide releasing factor" "Cancer-related genes, Ciliopathy, Cone-rod dystrophy, Deafness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ciliated cells: 102.7;Endothelial cells: 83.3;Lymphatic endothelial cells: 88.9;Rod photoreceptor cells: 79.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 14.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 14.8" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001593, HPA073455" Approved Supported "Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 36: Non-specific - mRNA processing" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "Golgi apparatus" "HPA001593: AB_1079835, HPA073455: AB_2686603" "unprognostic (3.22e-2)" "unprognostic (1.16e-2)" "unprognostic (5.04e-2)" "unprognostic (1.08e-1)" "unprognostic (3.20e-1)" "unprognostic (9.94e-2)" "unprognostic (3.46e-2)" "unprognostic (6.32e-2)" "unprognostic (2.04e-1)" "unprognostic (1.37e-1)" "unprognostic (1.96e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-6)" "unprognostic (1.93e-1)" "unprognostic (7.59e-2)" "unprognostic (8.96e-3)" "unprognostic (1.61e-3)" RPGRIP1 "CORD13, LCA6, RGI1, RPGRIP" ENSG00000092200 "RPGR interacting protein 1" Q96KN7 14 21280083-21351301 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Cone-rod dystrophy, Disease variant, Glaucoma, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 82 "retina: 179.2;testis: 57.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 127.4;Early spermatids: 179.3;Late spermatids: 122.7;Rod photoreceptor cells: 128.4;Spermatocytes: 43.4" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.0" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 8.8" "Group enriched" "Detected in many" 28 "dendritic cells: 3.2;granulocytes: 8.8;monocytes: 3.6" "Low cancer specificity" "Detected in single" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA042955, HPA060190" Supported Supported NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 6: Non-specific - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 19 "HPA042955: AB_2678239, HPA060190: AB_2684218" "unprognostic (9.02e-4)" "unprognostic (3.64e-2)" "unprognostic (1.89e-1)" "unprognostic (1.86e-1)" "unprognostic (7.35e-2)" "unprognostic (1.82e-2)" "unprognostic (2.99e-2)" "unprognostic (1.14e-1)" "unprognostic (2.92e-1)" "unprognostic (1.99e-1)" "unprognostic (3.94e-3)" "unprognostic (2.33e-1)" "unprognostic (7.31e-3)" "unprognostic (2.86e-2)" "unprognostic (2.87e-1)" "unprognostic (3.13e-1)" "unprognostic (1.83e-2)" RRM2B p53R2 ENSG00000048392 "Ribonucleotide reductase regulatory TP53 inducible subunit M2B" Q7LG56 8 102204502-102238961 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Deoxyribonucleotide synthesis, DNA damage, DNA repair" Oxidoreductase "Deafness, Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006854, HPA028812" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 35: Non-specific - Mitochondria" "Cluster 21: Non-specific - Metabolism" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Neutrophils - Degranulation" 3 "Nucleoplasm, Cytosol" "CAB006854: , HPA028812: AB_10602246" "unprognostic (7.76e-3)" "unprognostic (4.14e-2)" "unprognostic (9.41e-3)" "unprognostic (3.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.28e-1)" "unprognostic (5.51e-2)" "unprognostic (1.35e-2)" "unprognostic (1.66e-1)" "unprognostic (9.40e-2)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-2)" "unprognostic (4.32e-1)" "unprognostic (1.47e-1)" "unprognostic (2.52e-1)" "unprognostic (7.17e-2)" RTN4IP1 NIMP ENSG00000130347 "Reticulon 4 interacting protein 1" Q8WWV3 6 106570771-106629498 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 45.5" "Heart muscle - Cardiomyocytes, Testis - Spermatogonia, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036357 Approved NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" 13 "HPA036357: AB_10673128" "prognostic unfavorable (9.18e-6)" "unprognostic (5.87e-2)" "unprognostic (2.20e-3)" "unprognostic (2.88e-1)" "unprognostic (3.51e-2)" "unprognostic (3.71e-2)" "unprognostic (7.37e-3)" "unprognostic (1.57e-1)" "unprognostic (7.77e-2)" "unprognostic (3.35e-1)" "unprognostic (2.51e-2)" "unprognostic (1.72e-2)" "prognostic favorable (8.55e-6)" "unprognostic (1.62e-1)" "unprognostic (9.82e-2)" "unprognostic (3.71e-1)" "unprognostic (5.76e-2)" SAG "ARRESTIN, RP47" ENSG00000130561 "S-antigen visual arrestin" P10523 2 233307816-233347055 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital stationary night blindness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 379 "retina: 1421.5" "Cell type enriched" "Detected in some" 5 "Rod photoreceptor cells: 5787.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "basal ganglia: 5.2" HPA004946 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 1 "HPA004946: AB_2667304" "unprognostic (4.76e-2)" "unprognostic (1.94e-2)" "unprognostic (4.52e-3)" "unprognostic (3.95e-1)" "unprognostic (8.54e-2)" "unprognostic (2.89e-2)" "unprognostic (3.86e-2)" "unprognostic (2.26e-2)" "unprognostic (1.78e-1)" "unprognostic (4.54e-1)" "unprognostic (4.57e-2)" "unprognostic (3.02e-1)" "unprognostic (1.12e-9)" "unprognostic (2.56e-1)" "unprognostic (1.61e-1)" "unprognostic (2.85e-1)" "unprognostic (1.03e-5)" SCO2 "MYP6, SCO1L" ENSG00000284194 "Synthesis of cytochrome C oxidase 2" O43819 22 50523568-50526461 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Cardiomyopathy, Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046943, HPA056254" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" 1 Mitochondria "HPA046943: AB_2732536, HPA056254: AB_2683080" SEMA4A "CORD10, FLJ12287, SEMAB, SemB" ENSG00000196189 "Semaphorin 4A" Q9H3S1 1 156147366-156177752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Angiogenesis, Differentiation, Immunity, Neurogenesis" "Developmental protein" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 50.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 90.5;Mucus glandular cells: 69.2;Salivary duct cells: 101.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 124.0;eosinophil: 120.5;intermediate monocyte: 132.8;myeloid DC: 183.2;neutrophil: 211.4;non-classical monocyte: 76.6" "Group enriched" "Detected in all" 13 "dendritic cells: 183.2;granulocytes: 211.4;monocytes: 132.8" "Cancer enhanced" "Detected in many" "lymphoma: 47.3;Myeloma: 105.7" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069136 Supported NA NA 3300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" 1 "HPA069136: AB_2686093" "unprognostic (1.90e-1)" "unprognostic (2.39e-2)" "unprognostic (4.24e-1)" "unprognostic (5.20e-2)" "unprognostic (8.04e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (3.51e-1)" "unprognostic (1.60e-2)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (8.20e-4)" "unprognostic (8.77e-2)" "unprognostic (4.63e-2)" "unprognostic (6.06e-2)" "unprognostic (1.28e-2)" SIPA1L3 "KIAA0545, SPAR3" ENSG00000105738 "Signal induced proliferation associated 1 like 3" O60292 19 37907208-38208369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 71.3;Inhibitory neurons: 83.7;Oligodendrocyte precursor cells: 93.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042072, HPA045480, HPA074988" Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA042072: AB_2677832, HPA045480: AB_2679342, HPA074988: " "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.86e-1)" "unprognostic (5.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-2)" "unprognostic (1.31e-2)" "unprognostic (5.48e-2)" "unprognostic (3.11e-1)" "unprognostic (6.05e-2)" "unprognostic (3.15e-1)" "unprognostic (5.43e-2)" "unprognostic (9.26e-3)" "unprognostic (6.45e-2)" "unprognostic (4.94e-2)" "unprognostic (5.36e-2)" "unprognostic (1.96e-2)" SLC24A1 "CSNB1D, HsT17412, KIAA0702, NCKX, NCKX1, RODX" ENSG00000074621 "Solute carrier family 24 member 1" O60721 15 65611366-65660995 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sensory transduction, Symport, Transport, Vision" "Congenital stationary night blindness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 35 "retina: 187.5" "Group enriched" "Detected in many" 4 "Lymphatic endothelial cells: 178.7;Rod photoreceptor cells: 296.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA039370 Enhanced Approved Microtubules NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Retina - Visual perception" "Cluster 15: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 66: Photoreceptor cells - Visual perception" Microtubules "HPA039370: AB_10960279" "unprognostic (9.47e-2)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (3.66e-3)" "unprognostic (6.39e-3)" "unprognostic (4.64e-1)" "unprognostic (8.82e-2)" "unprognostic (1.86e-1)" "unprognostic (4.69e-2)" "unprognostic (3.94e-1)" "unprognostic (2.01e-1)" "unprognostic (9.91e-2)" "prognostic favorable (2.33e-6)" "unprognostic (8.45e-2)" "unprognostic (9.22e-2)" "unprognostic (3.04e-2)" "unprognostic (1.96e-2)" SLC25A4 "AAC1, ANT1, PEO2, PEO3, T1" ENSG00000151729 "Solute carrier family 25 member 4" P12235 4 185143266-185150382 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Host-virus interaction, Transport" "Cardiomyopathy, Disease variant, FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 237.2;skeletal muscle: 184.0;tongue: 333.2" "Cell type enriched" "Detected in all" 6 "Cardiomyocytes: 6374.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046835, HPA071684" Approved Supported Mitochondria NA NA 380000 "Cluster 24: Non-specific - Transcription" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 68: Cardiomyocytes - Muscle contraction" 2 Mitochondria "HPA046835: AB_2679831, HPA071684: AB_2686431" "unprognostic (4.19e-2)" "unprognostic (1.06e-2)" "unprognostic (3.11e-1)" "unprognostic (8.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.90e-3)" "unprognostic (8.25e-2)" "unprognostic (1.26e-2)" "unprognostic (7.87e-2)" "unprognostic (1.60e-1)" "prognostic favorable (3.41e-4)" "unprognostic (2.05e-1)" "prognostic favorable (0.00e+0)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (1.73e-1)" "unprognostic (8.28e-3)" SLC39A5 ENSG00000139540 "Solute carrier family 39 member 5" Q6ZMH5 12 56230049-56237846 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "intestine: 230.5;kidney: 105.8;liver: 167.0;pancreas: 297.9" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 802.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 30.6;liver cancer: 36.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "colorectal cancer: 20.4;Gastric cancer: 12.0;liver cancer: 22.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA018423 Approved Nucleoplasm,Vesicles NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" Vesicles Nucleoplasm "HPA018423: AB_1857154" "unprognostic (5.94e-3)" "unprognostic (8.29e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-7)" "unprognostic (1.73e-1)" "unprognostic (7.79e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.93e-3)" "prognostic favorable (5.05e-4)" "unprognostic (2.75e-1)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.96e-4)" SLC4A11 "BTR1, CDPD1, CHED2, dJ794I6.2, FECD4, NaBC1" ENSG00000088836 "Solute carrier family 4 member 11" Q8NBS3 20 3227417-3239559 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Symport, Transport" "Corneal dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 49.8;salivary gland: 52.4;thyroid gland: 59.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 28.7;Club cells: 28.2;Collecting duct cells: 101.1;Ionocytes: 67.0;Salivary duct cells: 39.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular Endothelial cells, Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018120, HPA058377" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA018120: AB_1857186, HPA058377: " "unprognostic (2.33e-1)" "prognostic favorable (9.03e-4)" "unprognostic (1.18e-2)" "unprognostic (3.05e-2)" "unprognostic (1.00e-1)" "unprognostic (6.52e-2)" "unprognostic (9.66e-3)" "unprognostic (3.73e-2)" "unprognostic (3.10e-3)" "unprognostic (1.52e-3)" "unprognostic (2.94e-1)" "unprognostic (2.64e-1)" "prognostic favorable (6.21e-6)" "unprognostic (7.37e-2)" "unprognostic (4.30e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-3)" SLC7A14 "KIAA1613, PPP1R142" ENSG00000013293 "Solute carrier family 7 member 14" Q8TBB6 3 170459548-170586075 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.5;pituitary gland: 7.1;retina: 5.9" "Group enriched" "Detected in some" 5 "Bipolar cells: 24.1;Excitatory neurons: 59.8;Horizontal cells: 29.6;Inhibitory neurons: 86.6;Oligodendrocytes: 62.7" "Group enriched" "Detected in some" 11 "glioma: 0.8;pancreatic cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 10.1" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045929 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 31 "Vesicles, Cytosol" "Nucleoplasm, Plasma membrane" "HPA045929: AB_2679501" "unprognostic (1.00e-1)" "unprognostic (9.56e-2)" "unprognostic (1.03e-1)" "unprognostic (4.15e-2)" "unprognostic (1.43e-2)" "unprognostic (7.46e-2)" "unprognostic (9.16e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (6.68e-3)" "unprognostic (6.36e-2)" "unprognostic (3.03e-6)" "unprognostic (1.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.71e-2)" "unprognostic (3.24e-3)" SNRNP200 "ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD" ENSG00000144028 "Small nuclear ribonucleoprotein U5 subunit 200" O75643 2 96274338-96321271 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029321 Approved Supported Nucleoplasm NA NA 78000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 12 Nucleoplasm "HPA029321: AB_10604096" "unprognostic (2.63e-2)" "unprognostic (1.45e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (2.48e-3)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "unprognostic (6.46e-2)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (2.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" SPATA7 "HSD3, LCA3" ENSG00000042317 "Spermatogenesis associated 7" Q9P0W8 14 88384924-88470350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 55.3" "Group enriched" "Detected in all" 8 "Early spermatids: 811.4;Late spermatids: 1242.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038082, HPA038083" Enhanced Supported Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 74: Spermatids - Flagellum assembly" "Cluster 16: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 11: Late spermatids - Unknown function" Cytosol "HPA038082: AB_10671738, HPA038083: AB_10671519" "unprognostic (2.09e-2)" "unprognostic (6.72e-2)" "unprognostic (1.10e-1)" "unprognostic (6.50e-3)" "unprognostic (3.22e-2)" "unprognostic (6.75e-2)" "unprognostic (1.29e-3)" "unprognostic (4.70e-2)" "unprognostic (1.70e-1)" "unprognostic (5.45e-3)" "prognostic favorable (4.16e-5)" "unprognostic (2.88e-1)" "prognostic favorable (2.50e-5)" "unprognostic (8.41e-2)" "unprognostic (1.29e-2)" "unprognostic (6.09e-2)" "unprognostic (2.81e-2)" SSBP1 "mtSSB, SSBP" ENSG00000106028 "Single stranded DNA binding protein 1" Q04837 7 141738334-141787922 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002866 Supported Supported Mitochondria NA NA 150000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 35: Non-specific - Mitochondria" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 15: Non-specific - Mixed function" 4 Mitochondria "HPA002866: AB_1080092" "unprognostic (2.95e-1)" "unprognostic (2.99e-1)" "unprognostic (2.49e-2)" "unprognostic (3.62e-2)" "unprognostic (7.36e-3)" "unprognostic (2.86e-2)" "prognostic unfavorable (4.42e-4)" "unprognostic (3.68e-2)" "unprognostic (6.03e-2)" "prognostic favorable (3.40e-4)" "unprognostic (9.23e-3)" "unprognostic (4.02e-1)" "unprognostic (9.65e-3)" "unprognostic (1.62e-1)" "unprognostic (9.38e-2)" "unprognostic (1.25e-2)" "unprognostic (9.58e-2)" TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 961.9;salivary gland: 454.7;skin 1: 425.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1666.8;Basal respiratory cells: 2850.6;Basal squamous epithelial cells: 1785.3;Club cells: 1989.2;Ductal cells: 1987.3;Ionocytes: 2021.5;Squamous epithelial cells: 2760.9;Suprabasal keratinocytes: 2420.8" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "choroid plexus: 3.9;white matter: 1.1" "Immune cell enhanced" "Detected in some" "eosinophil: 15.1" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.1;monocytes: 4.2" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 603.0;head and neck cancer: 792.6" "Liver - Cholangiocyte, Pancreas - Ductal cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" 4 "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: AB_10960710, HPA055067: AB_2682687" "unprognostic (1.80e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (7.91e-2)" "prognostic favorable (3.99e-4)" "unprognostic (7.10e-2)" "unprognostic (2.55e-1)" "unprognostic (6.91e-3)" "unprognostic (2.50e-1)" TCF4 "bHLHb19, E2-2, ITF2, SEF2-1B" ENSG00000196628 "Transcription factor 4" P15884 18 55222185-55664787 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Disease variant, Epilepsy, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 788.5;dendritic cells: 1062.4;Inhibitory neurons: 1126.8;Oligodendrocyte precursor cells: 675.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "memory B-cell: 174.1;naive B-cell: 147.6;plasmacytoid DC: 560.8" "Group enriched" "Detected in many" 33 "B-cells: 174.1;dendritic cells: 560.8" "Cancer enhanced" "Detected in all" "Neuroblastoma: 66.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020722, HPA025958" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 62: Connective tissue - ECM organization" "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 124 "Nucleoplasm, Cytosol" "CAB020722: , HPA025958: AB_1857849" "unprognostic (2.11e-1)" "unprognostic (9.10e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-2)" "unprognostic (8.64e-2)" "unprognostic (1.79e-2)" "unprognostic (3.29e-2)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (1.99e-3)" "unprognostic (2.68e-2)" "unprognostic (2.76e-3)" "prognostic unfavorable (9.95e-4)" TDRD7 PCTAIRE2BP ENSG00000196116 "Tudor domain containing 7" Q8NHU6 9 97412096-97496125 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 61.1" "Cell type enhanced" "Detected in many" "Early spermatids: 44.3;Microglial cells: 32.2;Rod photoreceptor cells: 35.8;Spermatocytes: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020800, HPA022250, HPA024529" Enhanced Supported "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 27: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 66: Photoreceptor cells - Visual perception" 3 "Cytoplasmic bodies" Nucleoplasm "CAB020800: , HPA022250: , HPA024529: AB_1857869" "unprognostic (8.22e-2)" "unprognostic (1.62e-2)" "unprognostic (3.28e-3)" "unprognostic (1.03e-1)" "unprognostic (2.88e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (5.91e-4)" "unprognostic (2.88e-2)" "unprognostic (9.86e-2)" "unprognostic (2.00e-1)" "unprognostic (1.06e-1)" "unprognostic (2.74e-2)" "prognostic favorable (4.76e-5)" "unprognostic (4.03e-2)" "unprognostic (2.90e-1)" "unprognostic (1.17e-2)" "unprognostic (2.67e-1)" TEAD1 "AA, TCF13, TEF-1" ENSG00000187079 "TEA domain transcription factor 1" P28347 11 12674421-12944737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 188.9;Astrocytes: 218.9;Skeletal myocytes: 182.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057339, HPA062471" Enhanced Nucleoplasm NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 Nucleoplasm "HPA057339: AB_2683413, HPA062471: AB_2684773" "unprognostic (1.00e-1)" "unprognostic (2.53e-2)" "unprognostic (8.84e-2)" "unprognostic (9.93e-3)" "unprognostic (2.05e-2)" "unprognostic (4.50e-1)" "unprognostic (1.50e-1)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" "unprognostic (4.40e-3)" "unprognostic (8.39e-2)" "unprognostic (4.76e-2)" "unprognostic (1.41e-2)" "unprognostic (7.08e-3)" "unprognostic (2.52e-1)" "unprognostic (3.14e-1)" "unprognostic (2.18e-2)" TGFBI "BIGH3, CDB1, CDGG1, CSD1, CSD2, CSD3, LCD1" ENSG00000120708 "Transforming growth factor beta induced" Q15582 5 136028988-136063818 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Sensory transduction, Vision" "Amyloidosis, Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 483.5;placenta: 441.9" "Cell type enhanced" "Detected in many" "dendritic cells: 338.1;Fibroblasts: 238.4;Hofbauer cells: 278.0;Kupffer cells: 248.0;Langerhans cells: 259.0;Macrophages: 234.9;Pancreatic endocrine cells: 728.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 7 "choroid plexus: 87.4;thalamus: 150.1" "Group enriched" "Detected in many" 32 "classical monocyte: 252.5;intermediate monocyte: 149.2;myeloid DC: 157.2;non-classical monocyte: 121.9;plasmacytoid DC: 325.2" "Group enriched" "Detected in all" 46 "dendritic cells: 325.2;monocytes: 252.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 2635.3" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008612, HPA017019" Enhanced "Secreted to blood" "Cell adhesion" NA NA 1600000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Connective tissue cells - ECM organization" 4 "HPA008612: AB_1857970, HPA017019: AB_2669511" "unprognostic (1.05e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.38e-3)" "prognostic favorable (1.17e-4)" "unprognostic (5.21e-3)" "unprognostic (5.53e-3)" "unprognostic (4.60e-2)" "unprognostic (8.71e-3)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.42e-3)" "unprognostic (2.26e-1)" "prognostic unfavorable (7.82e-10)" "unprognostic (8.81e-3)" "unprognostic (1.73e-2)" "unprognostic (3.42e-1)" "unprognostic (1.70e-3)" TIMP3 SFD ENSG00000100234 "TIMP metallopeptidase inhibitor 3" P35625 22 32801705-32863041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1559.0;Alveolar cells type 1: 1732.8;Endothelial cells: 924.7;Fibroblasts: 1235.9;Leydig cells: 1359.9;Lymphatic endothelial cells: 1097.0;Peritubular cells: 1870.2;Sertoli cells: 1112.4;Smooth muscle cells: 1255.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 604.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068391 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "Enzyme inhibitor" NA NA 700000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 Vesicles "Golgi apparatus" "HPA068391: " "unprognostic (4.98e-2)" "unprognostic (1.77e-3)" "unprognostic (1.60e-1)" "unprognostic (8.53e-4)" "unprognostic (1.67e-2)" "unprognostic (1.05e-2)" "unprognostic (7.01e-2)" "unprognostic (3.22e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (1.90e-5)" "unprognostic (3.92e-1)" "unprognostic (1.95e-1)" "prognostic favorable (1.50e-4)" "unprognostic (2.66e-3)" "unprognostic (1.44e-2)" "unprognostic (2.55e-3)" "unprognostic (3.11e-2)" TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" Receptor "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Hofbauer cells: 72.9;Kupffer cells: 156.6;Macrophages: 80.4;monocytes: 178.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.9" "Cancer enhanced" "Detected in many" "Brain cancer: 11.7" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophil_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004025, HPA049174" Approved Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Neutrophils - Degranulation" 10 "Golgi apparatus, Plasma membrane" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" TMEM126A "DKFZp586C1924, OPA7" ENSG00000171202 "Transmembrane protein 126A" Q9H061 11 85647967-85656547 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 201.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046648 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 23: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA046648: AB_2679737" "unprognostic (3.79e-2)" "unprognostic (4.75e-3)" "unprognostic (2.08e-3)" "unprognostic (1.08e-3)" "unprognostic (2.08e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (8.60e-5)" "unprognostic (8.25e-2)" "unprognostic (6.00e-3)" "unprognostic (2.66e-2)" "unprognostic (1.02e-2)" "unprognostic (6.93e-2)" "unprognostic (1.25e-1)" "unprognostic (1.87e-2)" "unprognostic (2.70e-1)" "unprognostic (6.94e-2)" "unprognostic (2.17e-1)" TOPORS "LUN, RP31, TP53BPL" ENSG00000197579 "TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase" Q9NS56 9 32540544-32552586 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, Ubl conjugation pathway" Transferase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 158.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 67.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 67.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060640, HPA065661" Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 21: Early spermatids - Spermatogenesis" Nucleoplasm "HPA060640: AB_2684334, HPA065661: AB_2685527" "unprognostic (1.75e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.37e-2)" "unprognostic (9.94e-2)" "prognostic favorable (7.07e-4)" "unprognostic (2.70e-1)" "unprognostic (3.61e-1)" "prognostic favorable (6.64e-6)" "unprognostic (1.22e-1)" "unprognostic (5.95e-2)" "unprognostic (3.13e-1)" "unprognostic (2.92e-1)" TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001065-31161160 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 17.0;skin 1: 4.7" "Group enriched" "Detected in some" 5 "Bipolar cells: 579.2;Melanocytes: 226.8" "Cancer enriched" "Detected in single" 179 "melanoma: 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 248 "skin cancer: 38.0" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Melanocytes, Testis - Early spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 25: Bipolar cells - Visual perception" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: AB_2669090, HPA071139: " "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (9.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-3)" "unprognostic (2.83e-1)" "unprognostic (2.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (7.84e-2)" "unprognostic (6.20e-4)" "unprognostic (1.48e-1)" "unprognostic (2.63e-2)" TSPAN12 "NET-2, TM4SF12" ENSG00000106025 "Tetraspanin 12" O95859 7 120787320-120858402 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 88.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 83.5;Collecting duct cells: 93.4;Distal tubular cells: 141.4;Glandular and luminal cells: 90.9;Proximal tubular cells: 90.7" "Cancer enhanced" "Detected in all" "renal cancer: 44.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Hepatocytes, Skin - Endothelial cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051570, HPA058244" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 3: Basal prostatic cells - Lipid metabolism" 21 Microtubules Vesicles "HPA051570: , HPA058244: AB_2683652" "unprognostic (2.40e-2)" "unprognostic (7.60e-2)" "unprognostic (3.66e-3)" "unprognostic (1.82e-2)" "unprognostic (3.97e-1)" "unprognostic (7.34e-3)" "unprognostic (1.60e-1)" "unprognostic (8.12e-2)" "unprognostic (1.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (9.53e-2)" "unprognostic (7.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.43e-1)" TTLL5 "KIAA0998, STAMP" ENSG00000119685 "Tubulin tyrosine ligase like 5" Q6EMB2 14 75633625-75955079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transcription Ligase "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.7" "Cell type enhanced" "Detected in many" "Early spermatids: 107.7;Excitatory neurons: 129.9;Inhibitory neurons: 109.4;Late spermatids: 95.2;Oligodendrocytes: 226.1;Rod photoreceptor cells: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" HPA032128 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Retina & Testis - Cilium" "Cluster 30: White matter - Myelination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 51: Oligodendrocytes - Unknown function" "Plasma membrane, Cytosol" "HPA032128: AB_10600835" "unprognostic (7.35e-2)" "unprognostic (7.29e-2)" "unprognostic (7.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (5.96e-2)" "unprognostic (7.21e-5)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (7.93e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-1)" "unprognostic (5.67e-3)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (8.97e-2)" "unprognostic (2.15e-2)" TUBA3D H2-ALPHA ENSG00000075886 "Tubulin alpha 3d" P0DPH8 2 131476119-131482934 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "heart muscle: 83.4;testis: 214.1" "Group enriched" "Detected in some" 4 "Early spermatids: 450.1;Spermatocytes: 665.5;Spermatogonia: 218.0" "Cancer enhanced" "Detected in many" "testis cancer: 7.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "CAB004972, HPA039247, HPA043684, HPA063394" Uncertain Supported Microtubules NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 31: Spermatocytes - Spermatogenesis" Microtubules "CAB004972: AB_425727, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "prognostic favorable (4.65e-4)" "unprognostic (6.66e-2)" "unprognostic (1.10e-1)" "unprognostic (2.96e-3)" "unprognostic (1.82e-1)" "unprognostic (1.50e-3)" "unprognostic (2.17e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (2.89e-1)" "unprognostic (1.08e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (4.75e-9)" "unprognostic (4.60e-2)" "unprognostic (2.28e-1)" "unprognostic (9.96e-4)" "unprognostic (2.28e-1)" TUBB3 "beta-4, CFEOM3, CFEOM3A, FEOM3" ENSG00000258947 "Tubulin beta 3 class III" Q13509 16 89921392-89938761 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 330.2" "Cell type enhanced" "Detected in many" "Astrocytes: 19.2;Ductal cells: 21.1;Excitatory neurons: 36.7;Exocrine glandular cells: 26.2;Gastric mucus-secreting cells: 21.2;Inhibitory neurons: 43.2;Late spermatids: 18.5;Oligodendrocyte precursor cells: 15.1;Pancreatic endocrine cells: 23.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 9 "B-cells: 2.5" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA 89000000 "Cluster 33: Brain - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" 4 Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (7.08e-2)" "unprognostic (3.37e-4)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "unprognostic (8.01e-2)" "unprognostic (3.12e-2)" "unprognostic (4.04e-3)" "unprognostic (1.12e-3)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (1.99e-2)" "unprognostic (1.38e-2)" "unprognostic (7.57e-2)" "unprognostic (1.27e-3)" "unprognostic (3.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.91e-2)" TUBB4B "Beta2, TUBB2C" ENSG00000188229 "Tubulin beta 4B class IVb" P68371 9 137241287-137243707 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, FDA approved drug targets, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ciliated cells: 1765.7;Early spermatids: 2123.9;Late spermatids: 2919.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010880, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium assembly" 1 Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010880: AB_609915, HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (2.24e-1)" "unprognostic (1.77e-3)" "unprognostic (1.50e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (9.98e-4)" "unprognostic (9.92e-3)" "unprognostic (2.90e-1)" "unprognostic (3.63e-1)" "unprognostic (2.34e-1)" "unprognostic (4.09e-2)" "unprognostic (2.47e-3)" "unprognostic (6.37e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.36e-6)" "unprognostic (1.69e-1)" TWNK "C10orf2, FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL" ENSG00000107815 "Twinkle mtDNA helicase" Q96RR1 10 100987367-100994403 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA replication" "Helicase, Hydrolase" "Deafness, Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002532 Uncertain NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA002532: AB_1078311" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "unprognostic (1.16e-1)" "unprognostic (2.19e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (7.82e-3)" "unprognostic (7.99e-2)" "unprognostic (1.22e-1)" "unprognostic (7.95e-2)" "unprognostic (7.52e-2)" "unprognostic (1.96e-2)" "unprognostic (9.46e-2)" "unprognostic (9.82e-3)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" "unprognostic (1.45e-1)" UBIAD1 "SCCD, TERE1" ENSG00000120942 "UbiA prenyltransferase domain containing 1" Q9Y5Z9 1 11273198-11296049 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Menaquinone biosynthesis, Ubiquinone biosynthesis" "Prenyltransferase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Sebaceous gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044862 Approved Vesicles NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 49: Non-specific - Transcription" 33 Vesicles "HPA044862: AB_2679117" "unprognostic (1.79e-2)" "unprognostic (2.26e-1)" "unprognostic (5.06e-2)" "unprognostic (1.74e-1)" "unprognostic (7.95e-3)" "unprognostic (7.55e-2)" "unprognostic (1.16e-2)" "unprognostic (2.01e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "prognostic favorable (6.80e-5)" "unprognostic (3.00e-1)" "unprognostic (3.89e-1)" "unprognostic (2.03e-2)" "unprognostic (1.25e-1)" UNC45B "CMYA4, UNC45" ENSG00000141161 "Unc-45 myosin chaperone B" Q8IWX7 17 35147817-35189345 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Myogenesis" "Chaperone, Developmental protein" "Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 59 "heart muscle: 96.8;skeletal muscle: 189.6;tongue: 146.0" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 216.5;Late spermatids: 61.9;Skeletal myocytes: 111.2" "Group enriched" "Detected in some" 5 "head and neck cancer: 0.9;testis cancer: 1.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Lineage enriched" "Detected in single" 10 "T-cells: 1.1" "Cancer enriched" "Detected in single" 17 "Sarcoma: 1.7" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA017861 Approved Cytosol NA NA "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 68: Cardiomyocytes - Muscle contraction" 1 Cytosol "HPA017861: AB_1847012" "unprognostic (7.17e-2)" "unprognostic (6.47e-3)" "unprognostic (9.36e-3)" "unprognostic (2.93e-1)" "unprognostic (1.49e-3)" "unprognostic (5.30e-2)" "unprognostic (3.07e-1)" "unprognostic (1.09e-2)" "unprognostic (5.46e-2)" "unprognostic (2.40e-2)" "unprognostic (8.46e-2)" "unprognostic (6.73e-2)" "unprognostic (1.13e-6)" "unprognostic (6.77e-2)" "unprognostic (5.05e-3)" "unprognostic (2.20e-1)" "unprognostic (2.21e-1)" USH1C "AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C" ENSG00000006611 "USH1 protein network component harmonin" Q9Y6N9 11 17493895-17544416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Hearing" "Cancer-related genes, Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 95.1;kidney: 52.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 203.0;Enteroendocrine cells: 95.9;Intestinal goblet cells: 93.0;Muller glia cells: 154.1;Paneth cells: 173.3;Proximal enterocytes: 432.4;Proximal tubular cells: 179.4;Undifferentiated cells: 94.6" "Group enriched" "Detected in many" 7 "colorectal cancer: 34.5;pancreatic cancer: 18.8;renal cancer: 29.4;stomach cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 76.6;Gastric cancer: 40.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Cholangiocyte, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB013690, HPA027398, HPA027492, HPA028033" Enhanced Enhanced Cytosol No NA "Cluster 55: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 4 Cytosol "CAB013690: , HPA027398: AB_10601775, HPA027492: AB_10601898, HPA028033: AB_10601782" "unprognostic (3.60e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-1)" "unprognostic (3.83e-2)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (2.22e-1)" "unprognostic (2.78e-1)" "unprognostic (1.51e-2)" "unprognostic (9.65e-2)" "prognostic favorable (9.41e-4)" "unprognostic (1.29e-2)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (2.61e-1)" USH1G "ANKS4A, FLJ33924, Sans" ENSG00000182040 "USH1 protein network component sans" Q495M9 17 74916083-74923256 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 7.6;skin 1: 2.7" "Group enriched" "Detected in some" 4 "Early spermatids: 5.4;Late spermatids: 20.0;Muller glia cells: 11.3;Suprabasal keratinocytes: 6.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.6;Gallbladder cancer: 3.8;head and neck cancer: 2.9" "Prostate - Urothelial cells, Testis - Late spermatids" "Region enriched" "Detected in single" 12 "olfactory bulb: 9.9" "Low region specificity" "Detected in single" HPA024360 Uncertain NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Late spermatids - Unknown function" 19 "HPA024360: AB_1858660" "unprognostic (2.95e-1)" "unprognostic (6.17e-2)" "unprognostic (6.34e-4)" "unprognostic (2.92e-2)" "unprognostic (8.74e-2)" "unprognostic (1.74e-1)" "unprognostic (5.59e-4)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (8.64e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (3.10e-4)" "unprognostic (1.57e-1)" "unprognostic (8.48e-2)" "unprognostic (2.25e-1)" "unprognostic (3.35e-2)" USP45 MGC14793 ENSG00000123552 "Ubiquitin specific peptidase 45" Q70EL2 6 99432325-99521728 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.6;Inhibitory neurons: 42.7;Oocytes: 167.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029602, HPA029604" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 39: Retina & Testis - Cilium" "Cluster 35: Non-specific - DNA binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 44: Oocytes - Unknown function" "Nucleoplasm, Cytosol" "HPA029602: AB_10600418, HPA029604: AB_10602283" "unprognostic (7.81e-3)" "unprognostic (3.10e-3)" "unprognostic (1.63e-2)" "unprognostic (6.62e-2)" "unprognostic (1.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.15e-2)" "unprognostic (1.01e-1)" "unprognostic (2.77e-2)" "unprognostic (8.65e-2)" "unprognostic (2.95e-3)" "unprognostic (1.10e-1)" "unprognostic (3.43e-3)" "unprognostic (1.13e-1)" "unprognostic (3.53e-1)" "unprognostic (1.43e-1)" "unprognostic (6.91e-2)" VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 72.9;placenta: 71.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 953.3;Fibroblasts: 344.3;Glandular and luminal cells: 293.1;Kupffer cells: 545.7;Macrophages: 552.5;Oligodendrocyte precursor cells: 1543.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 89.0" "Group enriched" "Detected in many" 20 "dendritic cells: 89.0;monocytes: 240.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 189.1" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" "No annotated function" NA NA 12000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Monocytes - Innate immune response" 2 Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" VEGFA "VEGF, VEGF-A, VPF" ENSG00000112715 "Vascular endothelial growth factor A" P15692 6 43770184-43786487 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 241.3;granulocytes: 274.5;Langerhans cells: 272.3" "Cancer enhanced" "Detected in all" "renal cancer: 79.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005429, CAB039240, HPA069116, CAB069907" Supported "Secreted to blood" "Growth factor" NA NA 562000 57000 "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 29: Monocytes - Innate immune response" 3 "CAB005429: AB_2212984, CAB039240: , CAB069907: AB_10001947, HPA069116: AB_2686089" "unprognostic (1.12e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (2.42e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (4.35e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (2.34e-5)" "unprognostic (5.10e-2)" "unprognostic (5.27e-3)" "unprognostic (2.30e-2)" "unprognostic (1.40e-1)" "unprognostic (1.00e-2)" "prognostic unfavorable (1.76e-5)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.73e-4)" VIM ENSG00000026025 Vimentin P08670 10 17228241-17237593 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 8495.8;Muller glia cells: 8155.4;Ovarian stromal cells: 5786.3;Schwann cells: 8718.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000080, HPA001762, CAB058687" Enhanced Supported "Intermediate filaments" NA NA 35000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 62: Connective tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 33: Non-specific - DNA binding" 86 "Intermediate filaments" "CAB000080: AB_2304493, CAB058687: AB_2665570, HPA001762: AB_1080568" "unprognostic (1.02e-1)" "unprognostic (2.58e-1)" "unprognostic (2.87e-2)" "prognostic favorable (9.75e-6)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "unprognostic (3.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (9.29e-2)" "unprognostic (5.61e-2)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.87e-3)" "unprognostic (7.32e-2)" "unprognostic (1.82e-1)" "unprognostic (9.47e-3)" VSX1 "PPCD, PPCD1, PPD" ENSG00000100987 "Visual system homeobox 1" Q9NZR4 20 25070885-25082141 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "Developmental protein, DNA-binding" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 15.1;retina: 34.4" "Cell type enriched" "Detected in some" 24 "Bipolar cells: 447.0" "Not detected" "Not detected" "Region enriched" "Detected in all" 4 "cerebellum: 29.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA079607 Approved Nucleoli NA NA "Cluster 28: Neuronal - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 25: Bipolar cells - Visual perception" Nucleoli "HPA079607: " "unprognostic (1.93e-1)" "unprognostic (6.63e-2)" "unprognostic (9.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.27e-1)" "unprognostic (1.97e-1)" "unprognostic (4.01e-1)" "unprognostic (8.64e-3)" "unprognostic (2.70e-2)" "unprognostic (1.35e-1)" "unprognostic (2.31e-9)" "unprognostic (1.53e-2)" "unprognostic (2.35e-1)" "unprognostic (3.07e-4)" "unprognostic (2.38e-1)" WDR36 "GLC1G, TA-WDRP, UTP21" ENSG00000134987 "WD repeat domain 36" 5 111092321-111130502 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037796, HPA037797" Supported Supported Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Liver & Kidney - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 12: Squamous epithelial cells - Keratinization" Nucleoli "HPA037796: AB_2675673, HPA037797: AB_10672725" "unprognostic (2.14e-1)" "unprognostic (4.56e-2)" "unprognostic (1.45e-2)" "unprognostic (2.81e-1)" "unprognostic (2.60e-1)" "unprognostic (1.09e-2)" "unprognostic (1.29e-2)" "unprognostic (1.64e-1)" "unprognostic (9.79e-2)" "unprognostic (7.10e-3)" "unprognostic (3.09e-1)" "unprognostic (1.92e-1)" "unprognostic (5.31e-2)" "unprognostic (1.12e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (4.91e-2)" WFS1 "DFNA14, DFNA38, DFNA6, DIDMOAD, WFS" ENSG00000109501 "Wolframin ER transmembrane glycoprotein" O76024 4 6269849-6303265 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cataract, Deafness, Diabetes insipidus, Diabetes mellitus, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 97.1;Extravillous trophoblasts: 130.0;Lymphatic endothelial cells: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Smooth muscle cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029128 Approved NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Neuronal - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 4: Extravillous trophoblasts - Unknown function" 315 "HPA029128: AB_10603460" "unprognostic (4.27e-2)" "unprognostic (5.05e-2)" "unprognostic (1.58e-1)" "prognostic favorable (1.13e-6)" "unprognostic (7.35e-2)" "unprognostic (1.29e-2)" "unprognostic (2.73e-2)" "unprognostic (6.97e-3)" "unprognostic (2.37e-1)" "unprognostic (1.78e-1)" "unprognostic (8.36e-3)" "unprognostic (5.33e-3)" "unprognostic (6.20e-2)" "unprognostic (5.02e-2)" "unprognostic (9.10e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (3.64e-2)" YME1L1 YME1L ENSG00000136758 "YME1 like 1 ATPase" Q96TA2 10 27110111-27155266 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" HPA066953 Approved Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 56: Non-specific - Unknown function" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 80: Non-specific - Transcription" Mitochondria "Nuclear bodies" "HPA066953: AB_2685753" "unprognostic (2.28e-3)" "unprognostic (3.00e-2)" "unprognostic (1.34e-1)" "unprognostic (7.19e-2)" "unprognostic (8.12e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (8.25e-6)" "unprognostic (7.08e-2)" "unprognostic (2.91e-1)" "unprognostic (9.24e-2)" "unprognostic (9.43e-3)" "unprognostic (1.64e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (5.53e-2)" "unprognostic (1.44e-2)" "unprognostic (7.09e-2)" ZEB1 "AREB6, BZP, FECD6, NIL-2-A, PPCD3, TCF8, ZEB, Zfhep, Zfhx1a" ENSG00000148516 "Zinc finger E-box binding homeobox 1" P37275 10 31318495-31529814 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 201.9;Endometrial stromal cells: 276.2;Excitatory neurons: 266.9;Inhibitory neurons: 250.3;Microglial cells: 458.1;Oligodendrocyte precursor cells: 908.9" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027524, CAB058686, CAB079943" Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 12: Heart muscle - Cardiac muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 Nucleoplasm Nucleoli "CAB058686: AB_2665569, CAB079943: , HPA027524: AB_1844977" "unprognostic (1.54e-1)" "unprognostic (3.08e-1)" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (4.85e-2)" "unprognostic (7.40e-2)" "unprognostic (1.34e-2)" "unprognostic (5.59e-2)" "unprognostic (1.30e-1)" "unprognostic (2.96e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (7.34e-6)" "unprognostic (5.59e-3)" "unprognostic (1.19e-1)" "unprognostic (1.62e-2)" "unprognostic (1.66e-2)" ZNF408 FLJ12827 ENSG00000175213 "Zinc finger protein 408" Q9H9D4 11 46701030-46705912 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017892 Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 56: Non-specific - Unknown function" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" 51 "Centriolar satellite, Cytosol" "HPA017892: AB_1859248" "unprognostic (7.54e-2)" "unprognostic (2.41e-1)" "unprognostic (3.02e-3)" "unprognostic (1.20e-1)" "unprognostic (6.87e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (6.59e-5)" "unprognostic (3.01e-2)" "unprognostic (6.89e-2)" "unprognostic (1.42e-1)" "unprognostic (7.13e-3)" "unprognostic (5.77e-2)" "unprognostic (3.38e-2)" "unprognostic (9.99e-3)" "unprognostic (9.24e-2)" "unprognostic (1.19e-1)" "unprognostic (2.09e-2)" ZNF513 "FLJ32203, RP58, Zfp513" ENSG00000163795 "Zinc finger protein 513" Q8N8E2 2 27377235-27380790 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" DNA-binding "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 41.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051493 Uncertain NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 13: Spermatids - Transcription" 3 "HPA051493: AB_2681505" "unprognostic (1.11e-1)" "unprognostic (1.68e-1)" "unprognostic (4.67e-3)" "unprognostic (1.16e-1)" "unprognostic (2.99e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (6.21e-5)" "unprognostic (2.86e-2)" "unprognostic (3.70e-2)" "unprognostic (1.00e-1)" "unprognostic (9.48e-3)" "unprognostic (1.18e-1)" "unprognostic (5.18e-3)" "unprognostic (9.31e-2)" "unprognostic (1.79e-1)" "unprognostic (1.75e-1)" "unprognostic (1.01e-3)" ZNF644 "BM-005, KIAA1221, MGC60165, MGC70410" ENSG00000122482 "Zinc finger protein 644" Q9H582 1 90915298-91022272 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Gallbladder cancer: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057795 Uncertain Uncertain Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Vesicles "HPA057795: AB_2683529" "unprognostic (8.20e-2)" "unprognostic (5.86e-3)" "prognostic favorable (4.27e-4)" "prognostic unfavorable (8.39e-4)" "unprognostic (3.19e-3)" "unprognostic (4.62e-3)" "unprognostic (8.04e-2)" "unprognostic (7.01e-2)" "unprognostic (2.44e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (2.61e-2)" "unprognostic (3.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.03e-1)" "unprognostic (3.07e-1)"