Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ADCYAP1R1 "PAC1, PAC1R, PACAPR" ENSG00000078549 "ADCYAP receptor type I" P41586 7 31052308-31111474 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.0;fallopian tube: 29.2" "Group enriched" "Detected in some" 4 "Astrocytes: 54.2;Inhibitory neurons: 43.7" "Cancer enriched" "Detected in some" 11 "glioma: 45.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Neuroblastoma: 36.1" "Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030739, HPA049877" Enhanced Enhanced Vesicles NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" Vesicles "HPA030739: AB_2732461, HPA049877: AB_2680928" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.16e-2)" "prognostic favorable (5.78e-4)" "unprognostic (2.17e-1)" "unprognostic (8.36e-2)" "unprognostic (4.93e-2)" "unprognostic (5.75e-2)" "unprognostic (3.50e-2)" "unprognostic (3.88e-1)" "unprognostic (1.58e-1)" "unprognostic (6.67e-3)" "unprognostic (6.43e-4)" "unprognostic (1.09e-3)" "unprognostic (9.55e-2)" "unprognostic (3.85e-2)" "unprognostic (2.75e-4)" ADGRA1 "GPR123, KIAA1828" ENSG00000197177 "Adhesion G protein-coupled receptor A1" Q86SQ6 10 133087924-133131675 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 26.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 24.4;Horizontal cells: 23.9;Inhibitory neurons: 23.6;Oligodendrocyte precursor cells: 27.4" "Cancer enriched" "Detected in single" 13 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bone cancer: 6.5" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042773 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "HPA042773: AB_10794764" "unprognostic (8.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (1.09e-2)" "unprognostic (7.51e-3)" "unprognostic (2.48e-2)" "unprognostic (3.33e-1)" "unprognostic (1.66e-1)" ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 29.4;Endometrial stromal cells: 45.0;Fibroblasts: 39.6;Leydig cells: 52.3;Lymphatic endothelial cells: 58.2;Muller glia cells: 26.3;Peritubular cells: 40.6;Smooth muscle cells: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 29.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008984, HPA012393" Uncertain Supported "Vesicles,Plasma membrane" NA NA 270000 "Cluster 62: Connective tissue - ECM organization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Plasma membrane" Vesicles "HPA008984: , HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" ADGRA3 "FLJ38547, GPR125, PGR21" ENSG00000152990 "Adhesion G protein-coupled receptor A3" Q8IWK6 4 22345071-22516066 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.5" "Cell type enhanced" "Detected in many" "Astrocytes: 210.2;Hepatocytes: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008904 Uncertain "Intracellular and membrane" Receptor NA NA 280000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 39: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 47: Astrocytes - Unknown function" "HPA008904: AB_1849258" "unprognostic (3.70e-1)" "unprognostic (9.01e-2)" "unprognostic (5.32e-3)" "unprognostic (8.27e-3)" "unprognostic (4.58e-2)" "unprognostic (1.55e-1)" "unprognostic (8.15e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (3.91e-2)" "unprognostic (8.77e-2)" "unprognostic (1.88e-1)" "unprognostic (1.78e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-3)" ADGRB1 BAI1 ENSG00000181790 "Adhesion G protein-coupled receptor B1" O14514 8 142449430-142545009 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity, Myogenesis, Neurogenesis, Phagocytosis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 46.9" "Cell type enhanced" "Detected in some" "Astrocytes: 55.7;Bipolar cells: 24.0;Excitatory neurons: 45.9;Horizontal cells: 46.6;Inhibitory neurons: 36.4;Oligodendrocyte precursor cells: 66.5" "Cancer enriched" "Detected in many" 5 "glioma: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" Receptor NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 70: DU4475 - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "unprognostic (9.57e-4)" "unprognostic (1.28e-1)" "unprognostic (3.87e-3)" "unprognostic (8.50e-3)" "unprognostic (9.98e-2)" "unprognostic (5.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.14e-2)" "unprognostic (2.76e-1)" "unprognostic (2.55e-1)" "unprognostic (6.48e-2)" "unprognostic (3.43e-1)" "unprognostic (7.30e-11)" "unprognostic (6.27e-2)" "unprognostic (7.42e-2)" "unprognostic (4.52e-3)" "unprognostic (3.29e-2)" ADGRB2 BAI2 ENSG00000121753 "Adhesion G protein-coupled receptor B2" O60241 1 31727117-31764893 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 77.5" "Cell type enhanced" "Detected in many" "Astrocytes: 19.8;Bipolar cells: 12.8;Excitatory neurons: 53.9;Horizontal cells: 27.7;Inhibitory neurons: 13.2;Oligodendrocyte precursor cells: 19.3" "Cancer enriched" "Detected in many" 4 "glioma: 20.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069175 Supported "Plasma membrane" NA NA 32000 "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA069175: " "prognostic favorable (6.46e-4)" "unprognostic (1.74e-1)" "unprognostic (7.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.90e-1)" "unprognostic (2.40e-1)" "unprognostic (8.17e-4)" "prognostic unfavorable (4.02e-5)" "unprognostic (2.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-3)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (1.75e-3)" "unprognostic (7.98e-2)" ADGRB3 "BAI3, KIAA0550" ENSG00000135298 "Adhesion G protein-coupled receptor B3" O60242 6 68635282-69390571 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 29.2;pituitary gland: 23.1" "Group enriched" "Detected in many" 10 "Astrocytes: 1702.7;Excitatory neurons: 3716.2;Inhibitory neurons: 2624.2;Oligodendrocyte precursor cells: 1910.7;Oligodendrocytes: 1127.0" "Cancer enriched" "Detected in single" 10 "glioma: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 12.1" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8600 "Cluster 22: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Neurons - Neuronal signaling" 3 "unprognostic (1.71e-1)" "unprognostic (9.01e-2)" "unprognostic (2.69e-1)" "unprognostic (3.72e-3)" "unprognostic (3.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (5.08e-5)" "unprognostic (4.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-3)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (8.16e-3)" ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 60.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 28.1;Cardiomyocytes: 34.0;Endometrial stromal cells: 45.9;Fibroblasts: 31.6;Mesothelial cells: 75.6;Microglial cells: 24.2;Sertoli cells: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Nuclear speckles,Plasma membrane" NA NA 1400000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Plasma membrane" "Nucleoplasm, Nuclear speckles" "HPA042395: AB_10796906, HPA076279: " "unprognostic (3.21e-1)" "unprognostic (1.49e-4)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.55e-3)" "unprognostic (1.63e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-5)" "unprognostic (1.31e-3)" "unprognostic (4.58e-1)" "unprognostic (2.15e-2)" "unprognostic (1.77e-3)" ADGRE1 "EMR1, TM7LN3" ENSG00000174837 "Adhesion G protein-coupled receptor E1" Q14246 19 6887566-6940459 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.7;lymphoid tissue: 14.4" "Group enriched" "Detected in some" 5 "Kupffer cells: 32.4;monocytes: 87.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 166.6;eosinophil: 325.5" "Group enriched" "Detected in many" 18 "granulocytes: 325.5;monocytes: 105.3" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 13.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA052809 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 29: Monocytes - Innate immune response" "HPA052809: AB_2681959" "unprognostic (2.06e-2)" "unprognostic (3.45e-1)" "unprognostic (1.32e-1)" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (6.93e-5)" "unprognostic (6.77e-2)" "unprognostic (1.18e-1)" "unprognostic (5.75e-2)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-7)" "unprognostic (6.69e-2)" "unprognostic (3.33e-4)" "unprognostic (1.11e-2)" "unprognostic (1.35e-1)" ADGRE2 "CD312, EMR2" ENSG00000127507 "Adhesion G protein-coupled receptor E2" Q9UHX3 19 14732392-14778560 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.8" "Cell type enhanced" "Detected in many" "granulocytes: 72.9;Kupffer cells: 72.1;Macrophages: 72.3;monocytes: 238.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 70.2;eosinophil: 74.8;intermediate monocyte: 46.9;neutrophil: 55.8;non-classical monocyte: 90.2" "Group enriched" "Detected in many" 9 "granulocytes: 74.8;monocytes: 90.2" "Cancer enhanced" "Detected in many" "Leukemia: 7.7" "Lung - Neutrophil_2" "Low region specificity" "Detected in many" HPA055200 Uncertain Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 18 Vesicles Cytosol "HPA055200: " "unprognostic (2.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (9.10e-2)" "unprognostic (3.58e-2)" "unprognostic (2.77e-2)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.32e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.35e-6)" "unprognostic (1.46e-1)" "unprognostic (2.45e-3)" "unprognostic (2.50e-1)" "unprognostic (1.01e-1)" ADGRE3 EMR3 ENSG00000131355 "Adhesion G protein-coupled receptor E3" Q9BY15 19 14619117-14690027 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.1;lymphoid tissue: 5.9" "Cell type enhanced" "Detected in some" "Macrophages: 7.7;Microglial cells: 3.6;monocytes: 21.0;Mucus glandular cells: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Group enriched" "Detected in many" 7 "basophil: 282.8;eosinophil: 510.3;neutrophil: 491.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 510.3" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.0" "Adipose visceral - Neutrophils, Stomach - Neutrophils" "Not detected" "Not detected" HPA015638 Uncertain "Secreted to blood" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "HPA015638: AB_1848039" "unprognostic (2.11e-4)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (5.69e-2)" "unprognostic (5.63e-2)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (8.07e-2)" "unprognostic (9.61e-2)" "unprognostic (9.11e-4)" "unprognostic (4.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.13e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" ADGRE5 "CD97, TM7LN1" ENSG00000123146 "Adhesion G protein-coupled receptor E5" P48960 19 14380501-14408725 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 209.5" "Cell type enhanced" "Detected in many" "dendritic cells: 152.0;monocytes: 445.8;NK-cells: 300.7;T-cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013707 Enhanced Approved Cytosol "Secreted to blood" Receptor NA Yes 10000000 2400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Cytosol "HPA013707: AB_1846345" "unprognostic (3.16e-1)" "unprognostic (1.80e-1)" "unprognostic (5.10e-2)" "unprognostic (2.30e-1)" "unprognostic (2.85e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (7.51e-2)" "unprognostic (6.06e-3)" "unprognostic (3.14e-2)" "unprognostic (1.08e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (2.08e-2)" "unprognostic (4.14e-2)" "unprognostic (2.44e-2)" "unprognostic (6.41e-2)" ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.0;kidney: 19.7;urinary bladder: 41.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 62.2;Ciliated cells: 66.8;Club cells: 124.5;Collecting duct cells: 101.1;Glandular and luminal cells: 55.9;Ionocytes: 157.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 62.2" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" Receptor NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" ADGRF3 "GPR113, hGPCR37, PGR23" ENSG00000173567 "Adhesion G protein-coupled receptor F3" Q8IZF5 2 26308173-26346817 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pancreas: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 10.8;Early spermatids: 6.1;Late spermatids: 29.8;Microglial cells: 5.4;Oligodendrocytes: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044500 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 55: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 11: Late spermatids - Unknown function" "Golgi apparatus" Cytosol "HPA044500: AB_10794290" "unprognostic (9.58e-3)" "unprognostic (2.13e-2)" "unprognostic (4.07e-1)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (6.68e-4)" "unprognostic (8.98e-3)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" "unprognostic (9.66e-4)" "unprognostic (2.29e-1)" "unprognostic (8.09e-2)" "unprognostic (3.53e-2)" "unprognostic (2.58e-1)" "unprognostic (4.08e-2)" "unprognostic (8.70e-5)" ADGRF4 "FLJ38076, GPR115, PGR18" ENSG00000153294 "Adhesion G protein-coupled receptor F4" Q8IZF3 6 47685864-47722021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 17.8;skin 1: 37.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.6;Distal enterocytes: 8.3;Extravillous trophoblasts: 17.3;Squamous epithelial cells: 16.5;Suprabasal keratinocytes: 32.1;Syncytiotrophoblasts: 9.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.2" "Region enriched" "Detected in single" 5 "hypothalamus: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.7" "Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "spinal cord: 2.0" "HPA007131, HPA007158" Enhanced Uncertain Mitochondria NA NA "Cluster 13: Skin - Cornification" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA007131: AB_2667756, HPA007158: AB_1849254" "unprognostic (1.40e-2)" "unprognostic (7.06e-3)" "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (3.79e-2)" "unprognostic (3.77e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-1)" "unprognostic (3.47e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.86e-1)" "unprognostic (1.66e-8)" "unprognostic (1.62e-3)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 102.7" "Cell type enhanced" "Detected in many" "Adipocytes: 393.9;Alveolar cells type 1: 205.3;Alveolar cells type 2: 303.0;Endothelial cells: 214.3;Microglial cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 11.7;pancreatic cancer: 6.7;Sarcoma: 6.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 209.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 220.3;Melanocytes: 140.9;NK-cells: 180.6;Syncytiotrophoblasts: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.5" "Lineage enriched" "Detected in many" 5 "T-cells: 160.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Prostate basal glandular cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" Receptor NA NA 32000 "Cluster 24: Non-specific - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 19: NK-cells - Adaptive immune response" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1198.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 10.6;Mucus glandular cells: 11.4;Oligodendrocyte precursor cells: 9.4;Prostatic glandular cells: 14.5;Secretory cells: 21.7;Serous glandular cells: 29.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 16.6" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 22000000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 75: Serous glandular cells - Salivary secretion" "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" ADGRG3 "GPR97, Pb99, PGR26" ENSG00000182885 "Adhesion G protein-coupled receptor G3" Q86Y34 16 57668277-57689378 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 145.6" "Cell type enriched" "Detected in some" 5 "Lymphatic endothelial cells: 41.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "cerebral cortex: 22.7" "Immune cell enhanced" "Detected in some" "eosinophil: 142.5;neutrophil: 170.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 170.3" "Group enriched" "Detected in some" 9 "Leukemia: 2.4;lymphoma: 3.1" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" HPA040469 Uncertain NA NA 1200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 9 "HPA040469: AB_10794032" "unprognostic (4.41e-3)" "unprognostic (3.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" "unprognostic (8.84e-2)" "unprognostic (1.64e-2)" "unprognostic (1.50e-4)" "unprognostic (5.25e-3)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.67e-3)" "unprognostic (4.75e-2)" "unprognostic (3.77e-1)" "unprognostic (1.00e-1)" "unprognostic (2.90e-1)" ADGRG4 "GPR112, PGR17, RP1-299I16" ENSG00000156920 "Adhesion G protein-coupled receptor G4" Q8IZF6 X 136300963-136416890 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 1.0;intestine: 2.4;retina: 1.1" "Group enriched" "Detected in some" 5 "Enteroendocrine cells: 61.8;Paneth cells: 44.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035324 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 72: Neuronal - Signal transduction" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA035324: AB_10671512" "unprognostic (3.40e-3)" "unprognostic (7.68e-5)" "unprognostic (7.61e-2)" ADGRG5 "GPR114, PGR27" ENSG00000159618 "Adhesion G protein-coupled receptor G5" Q8IZF4 16 57542643-57591681 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 3.8;lymphoid tissue: 10.2" "Cell type enhanced" "Detected in some" "B-cells: 6.2;dendritic cells: 30.0;Microglial cells: 10.7;NK-cells: 27.1;Plasma cells: 16.9;T-cells: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 126.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 11.0;lymphoma: 6.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA007133 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" "Nuclear membrane, Vesicles" Nucleoplasm "HPA007133: AB_1849253" "unprognostic (6.11e-3)" "prognostic favorable (4.25e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (6.14e-2)" "unprognostic (1.14e-2)" "unprognostic (6.43e-2)" "unprognostic (1.42e-2)" "unprognostic (8.09e-4)" "unprognostic (3.80e-3)" "unprognostic (3.02e-3)" "unprognostic (1.91e-1)" "unprognostic (4.37e-3)" "unprognostic (7.69e-3)" "unprognostic (4.52e-1)" "unprognostic (1.62e-3)" "unprognostic (6.32e-3)" ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 69.7;placenta: 45.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 110.5;Suprabasal keratinocytes: 40.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017346 Approved NA NA 110000000 "Cluster 11: Liver - Plasma proteins" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Hepatocytes - Metabolism" "HPA017346: AB_1849260" "unprognostic (1.04e-2)" "unprognostic (2.72e-2)" "unprognostic (7.37e-2)" "unprognostic (3.00e-2)" "unprognostic (8.64e-4)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.46e-1)" "unprognostic (6.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.97e-2)" "unprognostic (4.59e-2)" ADGRG7 "FLJ14454, GPR128" ENSG00000144820 "Adhesion G protein-coupled receptor G7" Q96K78 3 100609601-100695479 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "intestine: 41.7;liver: 24.0" "Cell type enhanced" "Detected in some" "Hepatocytes: 22.4;Intestinal goblet cells: 9.5;Paneth cells: 20.1;Proximal enterocytes: 34.0" "Cancer enhanced" "Detected in some" "stomach cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.8;Brain cancer: 1.3" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056451 Approved "Plasma membrane" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 3 "Plasma membrane" "HPA056451: " "unprognostic (1.65e-1)" "unprognostic (1.10e-1)" "unprognostic (2.79e-1)" "unprognostic (8.46e-3)" "unprognostic (1.26e-1)" "unprognostic (6.71e-2)" "unprognostic (9.37e-3)" "unprognostic (2.84e-5)" "unprognostic (1.17e-1)" "unprognostic (2.16e-1)" "unprognostic (6.77e-2)" ADGRL1 "CIRL1, KIAA0821, LEC2, LPHN1" ENSG00000072071 "Adhesion G protein-coupled receptor L1" O94910 19 14147743-14206187 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.2;Excitatory neurons: 51.0;Horizontal cells: 54.1;Inhibitory neurons: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037974 Uncertain NA NA 180000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "HPA037974: AB_10675623" "unprognostic (5.52e-2)" "unprognostic (3.89e-1)" "unprognostic (1.04e-1)" "unprognostic (5.52e-3)" "unprognostic (6.29e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" "unprognostic (5.39e-2)" "unprognostic (2.73e-1)" "unprognostic (5.68e-2)" "prognostic favorable (1.14e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.45e-4)" "unprognostic (7.65e-3)" "unprognostic (1.32e-1)" "unprognostic (3.06e-2)" "unprognostic (2.18e-1)" ADGRL2 "CIRL2, KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81993932 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Excitatory neurons: 873.5;Inhibitory neurons: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Endothelial cells, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 700000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61200326-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.1" "Group enriched" "Detected in many" 11 "Astrocytes: 553.9;Excitatory neurons: 672.7;Inhibitory neurons: 706.4;Oligodendrocyte precursor cells: 1220.7;Oligodendrocytes: 551.2" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 8.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.8" "Group enriched" "Detected in many" 6 "Adipocytes: 559.4;Endothelial cells: 298.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 12.2;thyroid cancer: 15.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "adrenal gland: 516.2" "Cell type enriched" "Detected in many" 11 "Astrocytes: 2093.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 26.4" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 47: Astrocytes - Unknown function" 1 "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 68.3;lung: 74.4" "Cell type enhanced" "Detected in many" "Adipocytes: 131.7;Endometrial stromal cells: 98.4;Endothelial cells: 262.9;Lymphatic endothelial cells: 297.8;Oligodendrocyte precursor cells: 275.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.7;Sarcoma: 23.1" "Colon - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 30.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 29.1;Basal respiratory cells: 28.6;Ciliated cells: 56.5;Club cells: 31.1;Glandular and luminal cells: 35.4;Ionocytes: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA 280000 "Cluster 34: B-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" CELSR2 "ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3" ENSG00000143126 "Cadherin EGF LAG seven-pass G-type receptor 2" Q9HCU4 1 109249539-109275751 "G-protein coupled receptors, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.2;skin 1: 24.1" "Cell type enhanced" "Detected in many" "Horizontal cells: 50.4;Oligodendrocytes: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013952 Uncertain Approved Cytosol NA NA 1300000 "Cluster 80: Non-specific - Endocytosis" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" Cytosol "HPA013952: AB_1846518" "unprognostic (4.46e-3)" "unprognostic (1.07e-2)" "unprognostic (3.00e-2)" "unprognostic (4.71e-2)" "unprognostic (2.19e-1)" "unprognostic (5.30e-2)" "unprognostic (3.51e-2)" "unprognostic (2.98e-1)" "unprognostic (1.33e-1)" "unprognostic (1.59e-2)" "unprognostic (1.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.94e-2)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-2)" "unprognostic (5.16e-2)" CELSR3 "ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2" ENSG00000008300 "Cadherin EGF LAG seven-pass G-type receptor 3" Q9NYQ7 3 48636463-48662886 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.7;pituitary gland: 7.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.1;Cone photoreceptor cells: 22.1;Excitatory neurons: 9.8;Horizontal cells: 20.8;Inhibitory neurons: 10.3;Rod photoreceptor cells: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062866 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA062866: AB_2684886" "unprognostic (7.80e-2)" "unprognostic (3.80e-2)" "unprognostic (4.89e-1)" "unprognostic (9.12e-4)" "unprognostic (1.51e-1)" "unprognostic (1.59e-6)" "unprognostic (3.61e-6)" "unprognostic (1.86e-1)" "unprognostic (1.46e-3)" "unprognostic (5.07e-2)" "unprognostic (2.13e-3)" "unprognostic (2.87e-3)" "unprognostic (3.26e-3)" "unprognostic (9.53e-2)" "unprognostic (1.42e-1)" "unprognostic (3.86e-2)" "unprognostic (1.73e-1)" CRHR1 "CRF-R, CRF1, CRHR" ENSG00000120088 "Corticotropin releasing hormone receptor 1" P34998 17 45784277-45835828 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 19.5;pituitary gland: 19.8" "Cell type enriched" "Detected in single" 10 "Bipolar cells: 1.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025251 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" 1 "CAB025251: " "unprognostic (4.59e-2)" "unprognostic (1.43e-2)" "unprognostic (2.59e-7)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (3.94e-2)" "unprognostic (2.48e-1)" "unprognostic (4.55e-4)" "unprognostic (1.65e-2)" "unprognostic (2.21e-1)" "unprognostic (3.33e-4)" "unprognostic (2.07e-5)" "unprognostic (3.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.59e-1)" CRHR2 "CRF-RB, CRF2, HM-CRF" ENSG00000106113 "Corticotropin releasing hormone receptor 2" Q13324 7 30651942-30700129 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 21.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 8.0;Horizontal cells: 11.3;Inhibitory neurons: 4.7" "Not detected" "Not detected" "Region enhanced" "Detected in all" "choroid plexus: 48.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 5.5" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Low region specificity" "Detected in many" HPA073345 Supported "Plasma membrane" "Secreted - unknown location" Receptor NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA073345: " "unprognostic (7.14e-2)" "unprognostic (4.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.24e-3)" "unprognostic (5.69e-2)" "unprognostic (8.58e-2)" "unprognostic (6.00e-2)" "unprognostic (1.86e-4)" "unprognostic (2.01e-1)" "unprognostic (3.07e-1)" "unprognostic (5.90e-4)" "unprognostic (4.02e-2)" "unprognostic (8.29e-4)" "unprognostic (3.73e-3)" "unprognostic (2.84e-3)" "unprognostic (1.81e-1)" "unprognostic (3.84e-1)" GCGR GGR ENSG00000215644 "Glucagon receptor" P47871 17 81804132-81814008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "kidney: 48.6;liver: 165.5" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 56.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 10.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071228 Uncertain "Golgi apparatus" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Hepatocytes - Metabolism" "Golgi apparatus" "HPA071228: AB_2686368" "unprognostic (3.28e-4)" "unprognostic (9.30e-2)" "unprognostic (2.20e-1)" "unprognostic (1.53e-4)" "unprognostic (1.11e-1)" "unprognostic (2.30e-3)" "unprognostic (4.38e-2)" "unprognostic (1.79e-3)" "unprognostic (2.18e-1)" "unprognostic (2.77e-1)" "unprognostic (3.09e-1)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (5.99e-3)" "unprognostic (1.71e-1)" "unprognostic (1.17e-3)" "unprognostic (8.36e-3)" GHRHR ENSG00000106128 "Growth hormone releasing hormone receptor" Q02643 7 30938669-30993254 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 351 "pituitary gland: 206.1" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Spermatocytes: 1.6;Spermatogonia: 2.6" "Cancer enhanced" "Detected in single" "liver cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "prostate cancer: 2.1" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Receptor NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 67: Spermatogonia - Spermatogenesis" "unprognostic (8.32e-2)" "unprognostic (1.45e-1)" "unprognostic (9.30e-2)" "unprognostic (1.39e-1)" "unprognostic (7.23e-2)" "unprognostic (4.15e-1)" "unprognostic (2.28e-2)" "unprognostic (1.54e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (1.43e-2)" "unprognostic (1.47e-1)" "unprognostic (5.87e-3)" GIPR ENSG00000010310 "Gastric inhibitory polypeptide receptor" P48546 19 45668221-45683722 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 22.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 30.8;Enteroendocrine cells: 17.7;Gastric mucus-secreting cells: 34.2;Rod photoreceptor cells: 18.5" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 4.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB022710, HPA068054" Uncertain Uncertain Vesicles NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" 2 Vesicles "CAB022710: , HPA068054: " "unprognostic (2.40e-2)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (3.70e-4)" "unprognostic (1.82e-2)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.85e-3)" "unprognostic (2.78e-1)" "unprognostic (1.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-2)" "unprognostic (2.59e-2)" GLP1R GLP-1R ENSG00000112164 "Glucagon like peptide 1 receptor" P43220 6 39048781-39091303 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 2.6;pancreas: 6.8;salivary gland: 2.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.0;Cardiomyocytes: 5.2;Exocrine glandular cells: 1.7;Inhibitory neurons: 1.2;Melanocytes: 1.7;Pancreatic endocrine cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.9" "Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells" "Region enriched" "Detected in many" 4 "basal ganglia: 20.7" "Low region specificity" "Detected in some" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 68: Cardiomyocytes - Muscle contraction" 10 "unprognostic (4.06e-3)" "unprognostic (5.38e-6)" "unprognostic (1.80e-2)" "unprognostic (4.16e-2)" "unprognostic (4.98e-2)" "unprognostic (3.55e-1)" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (9.76e-2)" "unprognostic (3.29e-1)" "unprognostic (1.73e-1)" "unprognostic (8.60e-3)" "unprognostic (2.47e-1)" "unprognostic (1.15e-2)" "unprognostic (1.42e-2)" GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 11.8;intestine: 13.0;urinary bladder: 11.4" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 26.6" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 17.9;liver cancer: 9.1;Rhabdoid: 8.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" GPR157 FLJ12132 ENSG00000180758 "G protein-coupled receptor 157" Q5UAW9 1 9100305-9129102 "G-protein coupled receptors, Predicted membrane proteins" Differentiation "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 57.4" "Group enriched" "Detected in many" 4 "Langerhans cells: 315.3;Schwann cells: 117.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 23.9" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA028697, HPA054948" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Dendritic cells - Antigen presentation" Cytosol "Plasma membrane" "HPA028697: AB_10601810, HPA054948: " "unprognostic (2.83e-3)" "unprognostic (1.13e-2)" "unprognostic (5.91e-2)" "unprognostic (5.42e-2)" "unprognostic (2.13e-4)" "unprognostic (7.11e-2)" "unprognostic (7.52e-3)" "unprognostic (3.60e-2)" "unprognostic (9.20e-2)" "unprognostic (1.26e-1)" "unprognostic (9.13e-3)" "unprognostic (1.42e-1)" "unprognostic (1.02e-2)" "unprognostic (1.70e-2)" "unprognostic (1.21e-1)" "unprognostic (4.30e-2)" "unprognostic (3.04e-3)" PTH1R "PTHR, PTHR1" ENSG00000160801 "Parathyroid hormone 1 receptor" Q03431 3 46877721-46903799 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 570.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Distal tubular cells: 49.2;Extravillous trophoblasts: 72.7;Late spermatids: 31.5;Proximal tubular cells: 214.6;Sertoli cells: 57.1" "Group enriched" "Detected in many" 4 "renal cancer: 18.8;testis cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 4.8" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075879 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 9 "HPA075879: " "unprognostic (1.26e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-5)" "unprognostic (7.46e-2)" "unprognostic (3.46e-1)" "unprognostic (5.02e-2)" "unprognostic (3.84e-3)" "unprognostic (5.47e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (7.51e-2)" "unprognostic (8.44e-2)" "prognostic favorable (6.79e-6)" "unprognostic (4.22e-3)" "unprognostic (1.50e-1)" "unprognostic (1.35e-4)" "unprognostic (6.62e-3)" PTH2R PTHR2 ENSG00000144407 "Parathyroid hormone 2 receptor" P49190 2 208359714-208854503 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 15.9" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 11.9;Excitatory neurons: 15.4;Proximal tubular cells: 14.6;Rod photoreceptor cells: 24.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA010655 Approved NA NA "Cluster 76: Retina - Visual perception" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" 2 "HPA010655: AB_2668333" "unprognostic (4.76e-3)" "unprognostic (1.39e-3)" "unprognostic (1.64e-1)" "unprognostic (5.78e-2)" "unprognostic (3.77e-1)" "unprognostic (8.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (3.45e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-1)" "unprognostic (1.09e-3)" "unprognostic (2.54e-3)" "unprognostic (6.87e-2)" "unprognostic (1.30e-2)" "unprognostic (1.37e-2)" SCTR ENSG00000080293 "Secretin receptor" P47872 2 119439843-119525301 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 25.8;pancreas: 66.0" "Group enriched" "Detected in some" 5 "Alveolar cells type 2: 29.6;Ductal cells: 96.2;Exocrine glandular cells: 95.2;Pancreatic endocrine cells: 28.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007269 Uncertain NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "HPA007269: AB_1856640" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (4.99e-2)" "unprognostic (5.82e-2)" "unprognostic (1.71e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (9.08e-2)" "unprognostic (7.35e-2)" "unprognostic (2.38e-2)" "unprognostic (6.11e-3)" "unprognostic (1.65e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-1)" "unprognostic (4.38e-2)" VIPR1 "HVR1, RDC1, VPAC1, VPAC1R" ENSG00000114812 "Vasoactive intestinal peptide receptor 1" P32241 3 42489299-42537573 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 128.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 39.6;Distal enterocytes: 54.6;Intestinal goblet cells: 52.2;Paneth cells: 89.4;Proximal enterocytes: 45.2" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 22 "dendritic cells: 2.1;monocytes: 1.8;T-cells: 2.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.7" "Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Group enriched" "Detected in many" 4 "amygdala: 6.4;basal ganglia: 4.5;cerebral cortex: 9.6;hippocampal formation: 7.7;white matter: 2.5" "Low region specificity" "Detected in all" HPA026777 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA026777: AB_10604003" "unprognostic (9.02e-2)" "unprognostic (9.34e-3)" "unprognostic (3.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.28e-1)" "unprognostic (1.47e-2)" "unprognostic (8.89e-4)" "unprognostic (4.00e-3)" "unprognostic (1.03e-1)" "unprognostic (2.95e-2)" "unprognostic (1.28e-2)" "unprognostic (2.72e-1)" "unprognostic (1.82e-3)" "unprognostic (7.70e-2)" "unprognostic (1.69e-1)" "unprognostic (1.03e-2)" "unprognostic (1.05e-2)" VIPR2 "VPAC2, VPAC2R" ENSG00000106018 "Vasoactive intestinal peptide receptor 2" P41587 7 159028175-159144867 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 65.6;Mesothelial cells: 96.5;Muller glia cells: 32.2;Oligodendrocyte precursor cells: 46.7;Rod photoreceptor cells: 43.1" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "plasmacytoid DC: 12.3" "Lineage enriched" "Detected in single" 17 "dendritic cells: 12.3" "Cancer enhanced" "Detected in some" "Leukemia: 5.2;Rhabdoid: 3.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Region enhanced" "Detected in many" "olfactory bulb: 27.0" "Low region specificity" "Detected in many" HPA062707 Approved Approved "Focal adhesion sites" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 28: Dendritic cells - Antigen presentation" "Focal adhesion sites" "HPA062707: AB_2684842" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (4.26e-2)" "unprognostic (2.04e-2)" "unprognostic (6.31e-2)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (8.58e-2)" "unprognostic (2.32e-2)" "unprognostic (1.02e-1)" "unprognostic (9.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (8.89e-2)"